Fig. 4. PPS mean crestal bone level change plotted against time (mean, 95 % CI)
Fig. 4. PPS mean crestal bone level change plotted against time (mean, 95 % CI)
Fig. 3. Participant flow diagram
Fig. 3. Participant flow diagram
Fig. 2. Restorative flow diagram
Fig. 2. Restorative flow diagram
Fig. 1. Clinical pictures in each procedure. a Before implant placement. b After abutment connection. c Temporary prosthesis. d Final prosthesis
Fig. 1. Clinical pictures in each procedure. a Before implant placement. b After abutment connection. c Temporary prosthesis. d Final prosthesis
Indicator
Prosthetic comforta
Appearanceb
Ability to chewc
Ability to tasted
Fittinge
General satisfactionf
Treatment arm
...
Treatment arm
Summary statistics
Baseline
6 months
Change from baseline to 6 months
...
Characteristics
Early loading arm
Conventional loading arm
Total
(N = 38)
(N =...
Loading criteria 1
Loading criteria 2
• Sufficient oral hygiene
• At least 1 mm bone volume around the implanta
• No major dehiscence (
Inclusion criteria
Age over 20 Patient who have missing teeth in premolar or molar site Good oral hygiene Predicted implant site has 1–3 quality of bone densityand enough quantity of bone Extraction socket in predicted implant site is completely healed (16 weeks or more)
...
Dard, M., Shiota, M., Sanda, M. et al. A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps.
Int J Implant Dent 2, 10 (2016). https://doi.org/10.1186/s40729-016-0040-8
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Received: 25 September 2015
Accepted: 23 March 2016
Published: 04 April 2016
DOI: https://d...
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...
Michel Dard, Makoto Shiota, Minoru Sanda, Yasutomo Yajima, Hideshi Sekine, and Shohei Kasugai state that there are no conflicts of interest.
MD mainly prepared the manuscript and figures. MS arranged this study, participated in its design and coordination, and helped to draft the manuscript. YY, HS, and SK managed the data collection from each centers of Tokyo Dental College Chiba Hospital (TDCC)...
College of Dentistry, New York University, New York, NY, USA
Michel Dard
Tokyo Medical and Dental University, Tokyo, Japan
Makoto Shiota, Minoru Sanda & Shohei Kasugai
Suidobashi Hospital, Tokyo Dental College, Tokyo, Japan
Yasutomo Yajima
School of Dentistry, Ohu University, Fukushima, Japan
Hideshi Sekine
Department of Oral Implantology and Regenerative Dental Medicine, Tokyo Medical ...
This trial was sponsored by Straumann Japan KK. The authors would like to acknowledge the assistance of Eusaku Watanabe and Nariyuki Maezawa (both Straumann Japan KK) for their contributions to the study.
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In conclusion, this study demonstrated that early implant loading was non-inferior to conventional implant loading in terms of crestal bone level change in a Japanese patient population in short follow-up period and single tooth gaps in molar regions. High implant survival and patient satisfaction rates, and a good safety profile, were also achieved.
Early loading of the implants showed a good safety profile, with a similar incidence in AEs between the early and conventional loading groups. The benefits to the patient for the early loading procedure were demonstrated by the patient satisfaction question “What does the patient think about the time taken until occlusal loading was started after implantation surgery?” All patients in the earl...
The implant survival rate of 100 % after 12 months is also in line with the results from previous studies with chemically modified SLA implants in various situations, including 100 % survival in early loading of mandibular overdentures [55], 100 % survival in single-tooth applications in the anterior maxilla [56], 96.8 % with maxillary sinus floor augmentation [57], and 98 and 97 % with imme...
This was a randomized, controlled, multicenter clinical trial to investigate whether the outcomes for chemically modified SLA implants in terms of change in crestal bone level from implant surgery to 6 months were non-inferior with early loading (25 ± 3 days) compared to conventional loading (13 ± 1 weeks). The difference in mean crestal bone level change between the early loading and...
In the PPS and FAS, the implant survival rate was 100 % after 12 months. In the PPS, the implant success rate was 100 % at all time points in both the conventional and early loading arms; however, in the FAS, the success rate in the conventional loading arm was 100 % at all time points, while in the early loading arm, success was 100 % at suture removal at 12-month follow-up and 95 % at the ...
The study enrolled 84 Japanese patients who had single missing tooth in the molar region. Since four patients were withdrawn due to the exclusion criteria (systemic disease, adjacent teeth with probing pocket depth deeper than 4 mm, mental disorder, and bone deficiency, respectively), 80 patients underwent implant placement. Two further patients were withdrawn before randomization because the ins...
In addition, periodontal examination, in the form of probing depth (PD) and bleeding on probing (BoP), was performed at pre-screening and at the 12-month follow-up.
Descriptive summary statistics were computed for all parameters, and quantitative parameters were described using mean, standard deviation, median, quartiles, minimum, and maximum. For qualitative variables, absolute and relative freq...
The primary endpoint was a change of crestal bone level between implant surgery (baseline) and final restoration (6 months), assessed by measuring the distance from the implant shoulder to the first bone-to-implant contact both mesially and distally to the implant.
Bone level was measured by a single reader on standardized periapical radiographs taken at baseline (day 0), suture removal (7–14...
When a patient fulfilled all inclusion criteria and had no exclusion criteria, then he/she got implant surgery and checked the condition met first criteria for loading (loading criteria 1 (LC1)) (Table 2).
All patients received Ti grade IV Straumann Standard Plus Regular Neck (SP RN) implants, 4.1 mm in diameter and 8, 10, or 12 mm in length, with SLActive® surface (Institut Straumann AG, Bas...
This study was designed as a randomized, controlled, multicenter clinical trial to evaluate non-inferiority of early loading compared to conventional loading of dental implants with a chemically modified SLA surface placed in single tooth gaps, involving three centers in Japan (Tokyo Medical and Dental University (TMDU), Tokyo Dental College Chiba Hospital (TDCC), and Tokyo Dental College Suidobas...
Early loading protocols have become relatively common procedures in many countries for implant restoration, but the procedure is much less common in Japan. The purpose of this study, therefore, was to investigate whether the chemically modified SLA implant with early loading was non-inferior to conventional loading, based on the amount of crestal bone change between baseline and 6 months after su...
The use of dental implants to replace missing or compromised teeth has been well documented clinically over many years. High implant survival rates have been demonstrated for over 10 [1–3], 15 [4], and 20 years [5, 6]. Long-term survival rates for single-tooth implants have been shown to be greater than those for tooth-supported restorations, e.g., fixed partial dentures (FPDs) [7, 8]. Good lon...
The aim of the study was to evaluate whether early loading of implants with a chemically modified sandblasted, large-grit, acid-etched (SLA) (SLActive®) surface was non-inferior to conventional loading in terms of change in crestal bone level.
This was a randomized, controlled, multicenter study. Patients requiring single-tooth rehabilitation in the posterior maxilla or mandible received implant...