Part of this study was supported by STDF reintegration grant number 489 and was performed in collaboration with the Oral Surgery Department, Faculty of Dentistry, Alexandria University, Egypt.

MNA prepared the specimens and performed the characterization process. He participated in preparation of histological section, data collection and analysis, and in preparation of the manuscript. RS performed the surgical phase of the study, provided animal care, looked after housing facilities, and participated in drafting the manuscript. Both authors read and approved the final manuscript.

Moustafa Aboushelib and Rehab Shawky declare that they have no competing interests.

Animal model was approved by the ethics committee of Alexandria University, Egypt, with authorization to publish on relevant data (STDF grant 489).

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