References : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [1]
Sah JP, Johnson NW, Batsakis JG. Oral cancer. London: Informa Healthcare; 2011. p. 3–32.
Japan Society for Oral Tumors. General rules for clinical and pathological studies on oral cancer. 1st ed. Tokyo: Kanehara-shuppan Co; 2010. p. 44–7.
Laprise C, Shahl HP, Madathil SA, et al. Periodontal diseases and risk of oral cancer in Southern India: results from the HeNCe Life Study. Int J Cancer. 2016;139:1512–9.
Schache A, Thavaraj S, Kalavrezos N. Osseointegrated implants: a potential route for squamous cell carcinoma of the mandible. Br J Oral Maxillofac Surg. 2008;46:397–9.
Kwok J, Eyeson J, Thompson I, et al. Dental implants and squamous cell carcinoma in the at risk patient—report of 3 cases. Br Dent J. 2008;205:543–5.
Bhatavadekar NB. Squamous cell carcinoma in association with dental implants: an assessment of previously hypothesized carcinogenic mechanisms and a case reports. J Oral Implantol. 2012;38:792–8.
Jeelani S, Rajkumar E, Mary GG, et al. Squamous cell carcinoma and dental implants: a systemic review of case reports. J Pharm Bioallied Sci. 2015;7:378–80.
Raiser V, Naaj IAE, Shlimi B, et al. Primary oral malignancy imitating peri-implantitis. J Oral Maxillofac Surg. 2016;74:1383–90.
Mikami T, Cheng J, Maruyama S, et al. Emergence of keratin 17 vs. loss of keratin 13: Their reciprocal immunohistochemical profiles in oral carcinoma in situ. Oral Oncol. 2011;47:497–503.
Nobusawa A, Sano T, Negishi A, et al. Immunohistochemical staining patterns of cytokeratins 13, 14, and 17 in oral epithelial dysplasia including orthokeratotic dysplasia. Pathlogy International. 2014;64:20–7.
Saughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium: clinical implications of multicentric origin. Cancer. 1953;6:963–8.
Bouda M, Gorgoulis VG, Kastrinakis NG, et al. “High risk” HPV types are frequently detected in potentially malignant and malignant oral lesions, but not in normal mucosa. Mod Pathol. 2000;13:644–53.
Jayaprakash V, Reid M, Hatton E, et al. Human papillomavirus types 16 and 18 in epithelial dysplasia of oral cavity and oropharynx: a meta-analysis. Oral Oncol. 2011;47:1048–54.
Serial posts:
- Abstract : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [1]
- Abstract : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [2]
- Background : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis
- Case presentation : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [1]
- Case presentation : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [2]
- Case presentation : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [3]
- Conclusions : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis
- Abbreviations : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis
- References : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [1]
- References : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [2]
- Author information : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [1]
- Author information : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis [2]
- Rights and permissions : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis
- About this article : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis
- Table 1 Summary of immunohistochemical findings of the present case : Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis
- Fig. 1. Well-circumscribed gingival swelling on the lingual side of the right side of the mandible : Primary peri-implant
- Fig. 2. Panoramic radiograph shows slight vertical bone resorption around the implants in the right side of the mandible : Primary peri-implant
- Fig. 3. Pathological microscopic examination reveals thickened squamous epithelia with slight nuclear atypism and disorders of the epithelial rete pegs accompanied by moderate grade inflammatory cell infiltration (HE staining, bar: 400 μm) : Primary peri-implant
- Fig. 4. Immunohistological findings show a negative staining mosaic pattern for keratin 13 (k13) and positive staining for keratin 17 (k17) (immunohistological staining, bar 400 μm) : Primary peri-implant
- Fig. 5. High p53, p63, and Ki-67 reactivity are also observed in the basal cell layer (immunohistological staining, bar 400 μm) : Primary peri-implant
- Fig. 6. Postoperative intraoral finding and radiograph : Primary peri-implant