All implants were loaded 3–6 months after implant surgery (conventional loading protocol); therefore, this parameter was not analyzed in this study.

The overall effect of gingival biotype and smile line on PES, WES, or VAS was studied using a general linear regression analysis for multivariate tests. Although both PES and WES were not affected (p = 0.580, p = 303; respectively), VAS was significantly affected by both gingival biotype and smile line (p = 0.009). Accordingly, smile line had a stronger impact on VAS than the gingival biotype (p = 0.002, p = 0.492, respectively). The VAS of patients with high and low, and high and medium smile lines differed significantly (p = 0.004, p = 0.002; respectively), while medium and low smile lines did not show significant variation (p = 0.777). High smile line had a stronger influence on VAS than low and medium smile lines.