Abstract
Osseointegration—the direct and functional anchorage of an implant to living bone—is the cornerstone of modern dental and orthopedic implantology. While high success rates (>90%) are routinely reported, failure remains a significant clinical problem with multifactorial etiology. Early failures occur prior to or during the establishment of osseointegration and are frequently linke...
Abstract
Osseointegration is a fundamental biological process governing the success and longevity of dental and orthopedic implants. While implant material properties and surgical techniques are crucial, systemic conditions significantly influence the healing cascade and bone–implant interaction. Systemic disorders such as diabetes mellitus, tobacco smoking, and autoimmune d...
The proliferative phase of bone healing plays a crucial role in the regeneration of bone tissue following an injury or implantation. It is marked by the migration of mesenchymal stem cells (MSCs) to the site of injury or implant surface, where these multipotent progenitor cells differentiate into osteoblasts. Osteoblasts are the bone-forming cells responsible for synthesizing the bone matrix, a pr...
Introduction
Dental implants have revolutionized the field of restorative dentistry by offering patients a durable, functional, and aesthetic solution for missing teeth. The key to their success lies in a biological process known as osseointegration, a phenomenon where a titanium or titanium-alloy implant fuses directly with the surrounding bone tissue. Osseointegration is critical for ensuring t...
Bassett et al. were the first to employ magnetic fields to promote fracture healing in a non-invasive and safe manner. Camilleri and McDonald investigated the effect of a static magnetic field using a Neodymium Iron-Boron magnet placed over a skull suture on a rat model and discovered that the mitotic activity of the cells was affected. Bruce et al. demonstrated that stimulation wi...