Results : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
During surgery, one sheep showed acute sinusitis at the test site. The sinus mucosa was perforated to allow sinus drainage and surgery was completed. During the healing period, no evident clinical complications were observed.
At the histomorphometric analysis, one sinus of the control group and one of the test group (corresponding to the sinusitis case) appeared to have lost almost all biomaterial. The results have thus been calculated on n = 6 and can be seen in Table 1. In one test site, the repositioned bone plate was apparently lost during the histological processing. Mean values and SDs are indicated in text and tables. The statistically significant differences are marked with an asterisk (*).
The newly formed bone was found surrounding and partially interpenetrating the particles of the biomaterial and in continuity with the lateral and medial walls of the sinus (Fig. 4a) and, when present, in continuity with the repositioned bony window (Fig. 4b).
After 4 months of healing, the newly formed bone proportions within the augmented sinus were 16.4 ± 5.6% at the test sites and 12.0 ± 3.7% at the control sites. In both groups, large amounts of interpenetrated graft were observed, in which bone propagated within the porosities of the biomaterial at fractions of 37.1 ± 7.5% and 35.3 ± 6.8% at the test and control sites, respectively (Fig. 4c, d). The total bone, composed of newly formed bone and interpenetrated graft, was 53.5 ± 7.6% at the test site (replaced bony window) and 47.3 ± 9.9% at the control site (Fig. 5).
The largest amounts of newly formed bone and total bone (composite bone) were found in the close-to-window region at the test sites. In this region, the proportion of the newly formed bone was 22.1 ± 12.6%* and 7.5 ± 64.5%* (P = 0.028) at the test and control sites, respectively. The respective percentages of the total composite bone (new bone plus bone interpenetrated to the graft material) were 66.1 ± 14.7%* at the test sites and 44.2 ± 15.1%* at the control sites (P = 0.046). In the middle region, a statistically significant difference in soft tissue amount was seen between the test (29.7 ± 4.9%*) and control (37.5 ± 10.1%*) sites (P = 0.046). No substantial differences were found in the submucosal and base regions (Fig. 6).
Serial posts:
- Abstract : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Introduction : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
- Introduction : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [2]
- Materials and methods : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
- Materials and methods : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [2]
- Materials and methods : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [3]
- Materials and methods : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [4]
- Results : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
- Results : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [2]
- Discussion : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
- Discussion : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [2]
- Discussion : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [3]
- Conclusion : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Availability of data and materials : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Abbreviations : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- References : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
- References : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [2]
- References : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [3]
- References : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [4]
- Acknowledgements : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Funding : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Author information : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [1]
- Author information : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep [2]
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- About this article : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Table 1 Percentages of the various tissues within the elevated area after 4 months of healing. Mean values ± standard deviations (P values) and median (25%; 75% percentiles) : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Table 2 Percentages of various tissues in the antrostomy area after 4 months of healing. Mean values ± standard deviations (P values) and median (25%; 75% percentiles) : Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep
- Fig. 1. Clinical view at a membrane site. a Skin and periosteum were separately elevated, and the facial sinus wall exposed. b A 12 × 8-mm window was cut and removed. c The Schneiderian membrane was carefully elevated. d A twisted wire was inserted in the middle of the long side of the window and the elevated sinus was grafted. e At the control site, a resorbable membrane was placed and secured with cyanoacrylate. f Membrane in situ : Bone plate repositioned over the antrostomy after
- Fig. 2. Clinical view at a bone plate site. a The bone window was removed. b The sinus mucosa was carefully elevated, and a twisted wire was placed. c The elevated sinus was grafted. d The access bony window was repositioned and secured with cyanoacrylate : Bone plate repositioned over the antrostomy after
- Fig. 3. a The elevated area was divided into four regions for morphometric analysis. RED: submucosa; GREEN: middle; YELLOW: base; PURPLE: close-to-window. INC: top of the infraorbital nerve canal : Bone plate repositioned over the antrostomy after
- Fig. 4. Photomicrographs of ground sections after 4 months of healing. a Bone formed from the base of the sinus. b Bone plate connected by bridges of the new bone to the close-to-window region. c Particle of the graft surrounded by new bone. d Overexposed image to show the new bone ingrowth within the granules of biomaterial : Bone plate repositioned over the antrostomy after
- Fig. 5. Graph representing the tissue percentages within the elevated area. No statistically significant differences were found : Bone plate repositioned over the antrostomy after
- Fig. 6. Graph representing new bone and composite bone percentages within the elevated area : Bone plate repositioned over the antrostomy after