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Table 5 Summary of OHIP-14 (N = 44 and respons...

OHIP domainMinimumMaximumMeanSDFunctional limitation072.341.70Physical pain071.161.51Psychological discomfort081.642.27Physical disability080.751.77Psychological disability081.182.11Social disability080.611.40Handicap080.701.71Total0648.49.7Table 5 Summary of OHIP-14 (N = 44 and response range 0–8)

Table 4 Correlation analyses : Patient experience ...

Outcome variablesCorrelationsSpearman’s rhoP valueOHRQoLOral health compared0.596

Table 3 Patient-reported outcomes : Patient experi...

QuestionResponseFrequencyOral healthVery good/good81.8%Quality of LifeVery good/good90.9%General healthVery good/good81.8%Pain after hip operationExcessive35.0%Satisfaction hip operationVery85.7%Post op infection in hip siteNo95.3%Visible scar on hipYes48.8%Acceptable scarYes20 of 21aReduced sensibility on hip siteNo86.0%Problem walkingNo92.9%Augmented bone block still presentNo6.8%New augmentatio...

Table 2 Patients’ demographic and lifestyle-rela...

VariableFrequencyN or Mean ± SD%Patients Female2454.5 Male2045.5Age (years)61.16 ± 13.10 Age at operation53.73 ± 13.07 Time from augmentation to completing questionnaire (months)93.55 ± 31.75 Civil status Married3068.2 Single1125.0 Widow(er)36.8Housing Alone1227.3 With another person2352.3 > two persons920.5Education Up to primary711.3 Up to secondary23...

Table 1 Summary of questions : Patient experience ...

CategoryResponseQuestion (1) Perceived health-status  General health“Very good” to “bad”  Oral health“Very good” to “bad”  Overall quality of life“Excellent” to “bad” (2) Lifestyle-related  Smoking“Yes,” “no,” or “sometimes”  Appetite“Good” to “bad” (3) Donor site-related  Pain“Yes” and “no”  Infection“Yes” a...

About this article : Patient experience following ...

Gjerde, C.G., Shanbhag, S., Neppelberg, E. et al. Patient experience following iliac crest-derived alveolar bone grafting and implant placement. Int J Implant Dent 6, 4 (2020). https://doi.org/10.1186/s40729-019-0200-8 Download citation Received: 10 October 2019 Accepted: 11 December 2019 Published: 05 February 2020 DOI: https://doi.org/10.1186/s40729-019-0200-8

Rights and permissions : Patient experience follow...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Supplementary information : Patient experience fol...

A self-administered questionnaire.

Additional information : Patient experience follow...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Patient experience following...

The Ethics Committee was contacted in 2015, and no ethical approval was needed since this was then considered a quality control study. Written consent was obtained from all participants. Not applicable. Cecilie G Gjerde, Siddharth Shanbhag, Evelyn Neppelberg, Kamal Mustafa, and Harald Gjengedal declare that they have no competing interests.

Author information : Patient experience following ...

Correspondence to Cecilie G. Gjerde.

Author information : Patient experience following ...

Department of Oral and Maxillofacial Surgery, Institute of Clinical Dentistry, University of Bergen, Årstadveien 19, 5009, Bergen, Norway Cecilie G. Gjerde & Evelyn Neppelberg Centre for Clinical Dental Research, Institute of Clinical Dentistry, University of Bergen, Bergen, Norway Cecilie G. Gjerde, Siddharth Shanbhag & Kamal Mustafa Department of Oral and Maxillofacial Surgery, Head an...

Funding : Patient experience following iliac crest...

This work was partially funded by the Research Council of Norway through the BEHANDLING project (grant no. 273551) and TROND MOHN Foundation, Norway (BFS2018TMT10).

Acknowledgements : Patient experience following il...

The staff and surgeons at the Department of Oral and Maxillofacial Surgery, Head and Neck Clinic, Haukeland University Hospital, Bergen. Randi Aursland, master student, who helped collecting data. The patients included in this study.

References : Patient experience following iliac cr...

Landes CA, Bundgen L, Laudemann K, Ghanaati S, Sader R. Patient satisfaction after prosthetic rehabilitation of bone-grafted alveolar clefts with nonsubmerged ITI Straumann dental implants loaded at three months. Cleft Palate Craniofac J. 2012;49(5):601–8. Reisine S, Freilich M, Ortiz D, Pendrys D, Shafer D, Taxel P. Quality of life improves among post-menopausal women who received bone augment...

References : Patient experience following iliac cr...

Locker D, Allen F. What do measures of ‘oral health-related quality of life’ measure? Community Dent Oral Epidemiol. 2007;35(6):401–11. Sischo L, Broder HL. Oral health-related quality of life: what, why, how, and future implications. J Dent Res. 2011;90(11):1264–70. Slade GD. Assessing change in quality of life using the Oral Health Impact Profile. Community Dent Oral Epidemiol. 1998;26...

References : Patient experience following iliac cr...

Hill NM, Horne JG, Devane PA. Donor site morbidity in the iliac crest bone graft. Aust N Z J Surg. 1999;69(10):726–8. Finkemeier CG. Bone-grafting and bone-graft substitutes. J Bone Joint Surg Am. 2002;84-A(3):454–64. Hernigou P, Desroches A, Queinnec S, Flouzat Lachaniette CH, Poignard A, Allain J, et al. Morbidity of graft harvesting versus bone marrow aspiration in cell regenerative thera...

References : Patient experience following iliac cr...

Schaaf H, Lendeckel S, Howaldt HP, Streckbein P. Donor site morbidity after bone harvesting from the anterior iliac crest. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(1):52–8. Sakkas A, Wilde F, Heufelder M, Winter K, Schramm A. Autogenous bone grafts in oral implantology-is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J I...

Abbreviations : Patient experience following iliac...

Health-related quality of life Oral Health Impact Profile-14 Oral health-related quality of life Patient-reported outcome measures Quality of life

Availability of data and materials : Patient exper...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Patient experience following iliac c...

Favorable OHRQoL and satisfaction were reported after advanced reconstruction with iliac crest-derived grafts and implant treatment in orally compromised patients. However, this treatment requires substantial resources including hospitalization and sick leave.

Discussion : Patient experience following iliac cr...

Patients in our study reported satisfaction with the augmentation and implant installation, and as these patients were orally compromised before the operation, their satisfaction with getting fixed teeth most likely improved their perceived oral health condition. This might also, in part, explain why they reported good OHRQoL. Thus, our findings indicate that a majority of patients tolerate the au...

Discussion : Patient experience following iliac cr...

An important finding in this study is that a majority of patients were very satisfied after iliac crest-derived alveolar bone grafting and implant therapy. Although 90% of the patients in our study had successful bone grafting, only 70.1% reported implant survival together with prosthetic rehabilitation after 1 year. These figures are lower than those reported in previous studies [2, 3, 9]. A rev...

Results : Patient experience following iliac crest...

The correlation analyses performed did not show a significant correlation between the complications at the donor site and implant loss (Table 4). The mean OHIP-14 score (Table 5) was 8.4 ± 9.7 (range 0–56) in 44 patients of whom 35 patients scored 14 or less. Nine patients scored a total sum of 1 [1], i.e. “hardly ever” impact on any single item and “at no time” on the remaining ...

Results : Patient experience following iliac crest...

The final sample consisted of 44 patients that responded and completed the questionnaire, giving a response rate of 74.6%: 24 women and 20 men, mean age of 61.2 years ± 13.1 (range 27–82 years). The mean time from augmentation surgery until completing the questionnaire was 7.8 years ± 2.65 (range 1.9–12 years). Summary of demographic and lifestyle-related data is presented (Tabl...

Methods : Patient experience following iliac crest...

Implants were placed 4–6 months after the grafting procedure. The implant installations were performed by different oral surgeons (not in the hospital) and different implant systems were used. The implants installed into the augmented bone were allowed to heal for an additional 4–6 months before loading. The records of the original 69 patients were examined with regard to (1) grafting sit...

Methods : Patient experience following iliac crest...

This cross-sectional retrospective cohort study was based on records from all patients (n = 69) who underwent advanced alveolar augmentation with autologous iliac bone grafts at the Department of Oral and Maxillofacial Surgery, Haukeland University Hospital, Bergen, Norway, over 10 years (2002–2012). These patients were orally compromised with severe chewing problems as well as speech diff...

Background : Patient experience following iliac cr...

Health-related QoL (HRQoL) is a dynamic concept referring to an individual’s subjective assessment and perspective of current general health condition as well as functional, social, and emotional well-being [23, 24]. Most people regard oral health as important for QoL, and this is mediated through the concept of oral health-related QoL (OHRQoL) [25]. In this regard, OHRQoL is an important PROM i...

Background : Patient experience following iliac cr...

Insufficient alveolar bone volume, as a result of periodontal disease, trauma, congenital anomalies and/or resorption atrophy, often presents a clinical challenge for optimal placement of dental implants for prosthetic rehabilitation. In such cases, augmentation of alveolar bone, with either autologous bone, allogeneic, xenogeneic, or alloplastic biomaterials, is a prerequisite for placing implant...

Abstract : Patient experience following iliac cres...

The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment in orally compromised patients. This cross-sectional retrospective cohort study included 59 patients (29 women and 30 men) with major functional problems, who underwent advanced alveolar augm...

Fig. 6. Graph representing new bone and composite ...

Fig. 6. Graph representing new bone and composite bone percentages within the elevated area Fig. 6. Graph representing new bone and composite bone percentages within the elevated area

Fig. 5. Graph representing the tissue percentages ...

Fig. 5. Graph representing the tissue percentages within the elevated area. No statistically significant differences were found Fig. 5. Graph representing the tissue percentages within the elevated area. No statistically significant differences were found

Fig. 4. Photomicrographs of ground sections after ...

Fig. 4. Photomicrographs of ground sections after 4 months of healing. a Bone formed from the base of the sinus. b Bone plate connected by bridges of the new bone to the close-to-window region. c Particle of the graft surrounded by new bone. d Overexposed image to show the new bone ingrowth within the granules of biomaterial Fig. 4. Photomicrographs of ground sections after 4 months of he...

Fig. 3. a The elevated area was divided into four ...

Fig. 3. a The elevated area was divided into four regions for morphometric analysis. RED: submucosa; GREEN: middle; YELLOW: base; PURPLE: close-to-window. INC: top of the infraorbital nerve canal Fig. 3. a The elevated area was divided into four regions for morphometric analysis. RED: submucosa; GREEN: middle; YELLOW: base; PURPLE: close-to-window. INC: top of the infraorbital nerve canal

Fig. 2. Clinical view at a bone plate site. a The ...

Fig. 2. Clinical view at a bone plate site. a The bone window was removed. b The sinus mucosa was carefully elevated, and a twisted wire was placed. c The elevated sinus was grafted. d The access bony window was repositioned and secured with cyanoacrylate Fig. 2. Clinical view at a bone plate site. a The bone window was removed. b The sinus mucosa was carefully elevated, and a twisted wire wa...

Fig. 1. Clinical view at a membrane site. a Skin a...

Fig. 1. Clinical view at a membrane site. a Skin and periosteum were separately elevated, and the facial sinus wall exposed. b A 12 × 8-mm window was cut and removed. c The Schneiderian membrane was carefully elevated. d A twisted wire was inserted in the middle of the long side of the window and the elevated sinus was grafted. e At the control site, a resorbable membrane was placed and secured...

Table 2 Percentages of various tissues in the antr...

 BoneSoft tissuePure graftInterpenetrated graftComposite boneReplaced windowCenter61.5 ± 46.982.5 (22.2; 96.9)21.7 ± 22.6*17.5 (3.1; 34.4)2.3 ± 4.3*0.0 (0.0; 2.3)7.9 ± 19.30.0 (0.0; 0.0)69.3 ± 38.582.5 (57.6; 96.9)Edge37.2 ± 37.021.6 (16.8; 55.8)41.0 ± 39.833.6 (9.2; 64.9)5.3 ± 7.31.6 (0.0; 9.1)13.8 ± 19.0*6.7 (0.0; 19.7)54.8 ± 34.162.9 (37.5; 69.7)MembraneCenter5.8 ± 2.1 (P = 0.116)5....

Table 1 Percentages of the various tissues within ...

 New boneSoft tissuePure graftInterpenetrated graftComposite boneReplaced windowTotal16.4 ± 5.618.8 (13.8; 20.3)32.9 ± 8.031.2 (27.7; 37.0)13.6 ± 4.212.0 (10.8; 16.2)37.1 ± 7.534.4 (31.7; 43.4)53.5 ± 7.652.4 (50.8; 57.8)Base15.0 ± 7.216.4 (10.1; 20.1)38.6 ± 14.334.5 (28.9; 47.1)13.4 ± 6.415.3 (13.1; 17.0)33.1 ± 11.133.1 (26.8; 40.0)48.0 ± 18.149.9 (36.9; 59.7)Middle16.9 ± 7.318.1 (11.2...

About this article : Bone plate repositioned over ...

Perini, A., Ferrante, G., Sivolella, S. et al. Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep. Int J Implant Dent 6, 11 (2020). https://doi.org/10.1186/s40729-020-0207-1 Download citation Received: 01 October 2019 Accepted: 04 February 2020 Published: 18 March 2020 DOI: https://doi.org/10.1186/s40729-020-0207-1

Rights and permissions : Bone plate repositioned o...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Bone plate repositioned o...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Bone plate repositioned over...

The research protocol was submitted to and approved by the Ethical Committee of the University of Medical Sciences, School of Dentistry, Havana, Cuba (prot. 013/2013). All the authors consent to publication. Alessandro Perini, Giada Ferrante, Stefano Sivolella, Joaquín Urbizo Velez, Franco Bengazi, and Daniele Botticelli declare that they have no competing interests.

Author information : Bone plate repositioned over ...

Correspondence to Alessandro Perini.

Author information : Bone plate repositioned over ...

Department of Neuroscience, Division of Dentistry, University of Padua, Via Giustiniani 2, 35128, Padua, Italy Alessandro Perini, Giada Ferrante & Stefano Sivolella Faculty of Dentistry, University of Medical Science, Havana, Cuba Joaquín Urbizo Velez & Franco Bengazi ARDEC Academy, Ariminum Odontologica, Rimini, Italy Daniele Botticelli You can also search for this author in ...

Funding : Bone plate repositioned over the antrost...

This study was funded by ARDEC Academy, Ariminum Odontologica s.r.l., Rimini, Italy. Degradable Solutions AG, a Sunstar Group Company, CH-8952 Schlieren ZH, Switzerland, provided free of charge the biomaterials used.

Acknowledgements : Bone plate repositioned over th...

Not applicable

References : Bone plate repositioned over the antr...

Iida T. Carneiro Martins Neto E, Botticelli D, Apaza Alccayhuaman KA, Lang NP, Xavier SP. Influence of a collagen membrane positioned subjacent the sinus mucosa following the elevation of the maxillary sinus: a histomorphometric study in rabbits. Clin Oral Implants Res. 2017 Dec;28(12):1567–76. Inal S, Yilmaz N, Nisbet C, Güvenç T. Biochemical and histopathological findings of N-butyl-2-cyano...

References : Bone plate repositioned over the antr...

Russell WMS, Burch RL. The principles of human experimental technique. London: Methuen; 1959. Schroeder HE, Münzel-Pedrazzoli S. Correlated morphometric and biochemical analysis of gingival tissue: morphometric model, tissue sampling and test of stereologic procedures. J Microsc. 1973 Dec;99(3):301–29. Sohn DS, Kim WS, An KM, Song KJ, Lee JM, Mun YS. Comparative histomorphometric analysis of ...

References : Bone plate repositioned over the antr...

Nosaka Y, Nosaka H, Arai Y. Complications of postoperative swelling of the maxillary sinus membrane after sinus floor augmentation. J Oral Sci Rehab. 2015;1:26–33. Tawil G, Tawil P, Khairallah A. Sinus floor elevation using the lateral approach and bone window repositioning I: clinical and radiographic results in 102 consecutively treated patients followed from 1 to 5 years. Int J Oral Maxillof...

References : Bone plate repositioned over the antr...

Tatum H Jr. Maxillary sinus grafting for endosseous implants. Lecture presented at the Annual Meeting of the Alabama Implant Study Group (1977); cited in Smiler DG, Johnson PW, Lozada JL, Misch C, Rosenlicht JL, Tatum OH Jr., Wagner JR. Sinus lift grafts and endosseous implants. Treatment of the atrophic posterior maxilla. Dent Clin North Am. 1992;36:151–86. Boyne PJ, James RA. Grafting of the ...

Abbreviations : Bone plate repositioned over the a...

Biphasic calcium phosphate Deproteinized Bovine Bone Mineral Hydroxyapatite Infraorbital nerve canal Standard deviation Beta-tricalcium phosphate

Availability of data and materials : Bone plate re...

All data and materials are available for control and consultation contacting the first author (alexperini@studioschweiger.it).

Conclusion : Bone plate repositioned over the antr...

In conclusion, the repositioning of the bone window after sinus floor elevation in sheep, compared with the use of a resorbable membrane, improved the closure of the antrostomy and led to a greater amount of the newly formed bone in the close-to-window zone of the grafted area. The bone window appeared partially bonded to the newly formed bone. Bridges of new bone from the edges of the antrostomy ...

Discussion : Bone plate repositioned over the antr...

In the present study, a lesser amount of bone was registered subjacent to the sinus mucosa compared with the other regions. This is in agreement with another experiment, in which a similar material was used for sinus augmentation in sheep [24]. A similar outcome was also reported in another study [27] that used DBBM xenograft for sinus augmentation in sheep. In that study, a collagen membrane was ...

Discussion : Bone plate repositioned over the antr...

In another similar experiment in sheep, the sinuses were augmented using a similar biphasic calcium phosphate (60% HA, 40% β-TCP) [24], the biomaterial used in the present study. The perforation of the sinus mucosa was performed at the test sites and a collagen membrane was placed to protect the perforation, while at control sites the elevated mucosa was left unprotected. After 12 weeks of heal...

Discussion : Bone plate repositioned over the antr...

The aim of the present study was to compare the healing of the augmented sinus in large animals, where the antrostomy was covered by a polylactic membrane or a repositioned bone plate, both secured with cyanoacrylate. No statistically significant differences were found between test and control sites in the bone formation within the augmented space. This outcome is in agreement with a similar stud...

Results : Bone plate repositioned over the antrost...

In the centre of the window area, at the test sites, in the analysed histological sections, the bone plate was still visible in five out of six sheep. It appeared partly remodelled and connected by the new bone formed in the sub-window area. Out of the five bone plates still present, three were bridged to the edges of the antrostomy, while in the two cases no contact was achieved in the observed s...

Results : Bone plate repositioned over the antrost...

During surgery, one sheep showed acute sinusitis at the test site. The sinus mucosa was perforated to allow sinus drainage and surgery was completed. During the healing period, no evident clinical complications were observed. At the histomorphometric analysis, one sinus of the control group and one of the test group (corresponding to the sinusitis case) appeared to have lost almost all biomateria...

Materials and methods : Bone plate repositioned ov...

The percentages of the new mineralised bone, soft or connective tissue, pure graft, graft interpenetrated by bone, and remnants of cyanoacrylate were evaluated. The total tissue percentages in the elevated space that included submucosa, middle, base, and sub-window regions were also calculated. Mean values and standard deviations (SDs) as well as the 25th, 50th (median), and 75th percentiles were...

Materials and methods : Bone plate repositioned ov...

After 4 months, the animals were anaesthetised and then euthanised with an overdose of pentobarbital sodium and subsequently perfused with 10% formalin. The maxilla was retrieved en bloc, trimmed, and immersed in formalin solution. All histological procedures were performed in the Laboratorio de Histologıa de la Facultad de Odontologıa de la Universidad de Ciencia Medica in Havana, Cuba. Bila...

Materials and methods : Bone plate repositioned ov...

Through an extra-oral approach, an oblique incision was made bilaterally along the sagittal axis between the facial tuberosity and the inferior orbital rim. The skin and periosteum were elevated separately, and the bony facial sinus wall was exposed on both sides of the maxilla (Fig. 1a). A 12-mm large and 8-mm high antrostomy was prepared using a burr (H254E Komet Dental, Trophagener Weg 25, L...

Materials and methods : Bone plate repositioned ov...

The research protocol was submitted to and approved by the Ethical Committee of the University of Medical Sciences, School of Dentistry, Havana, Cuba (prot. 013/2013). Eight female Pelibuey sheep, with a mean body weight of approximately 35 kg and a mean age of approximately 3 years, were provided by the Centro Nacional para la Producción de Animales de Laboratorio (CENPALAB) in Havana, Cuba...

Introduction : Bone plate repositioned over the an...

To prevent the movement of the bony plate and to gain adequate stability, cyanoacrylate has been suggested to glue the plate to the bony edges of the antrostomy [17]. Cyanoacrylates (as methyl 2-cyanoacrylate or ethyl 2-cyanoacrylate) are widely used in surgery and have shown good compatibility [18] and biomechanical strength for fixation of grafts [19]. In an experiment in rabbits [17], the antro...

Introduction : Bone plate repositioned over the an...

Sinus floor elevation is a commonly used technique to increase bone volume in the posterior maxilla prior to implant placement. This procedure was first developed by Tatum in 1977 [1], modified by Boyne and James in 1980 [2], and further modified over time. In this well-described technique, a bony window is created on the lateral wall of the sinus with a round burr, and the membrane elevated. Diff...

Abstract : Bone plate repositioned over the antros...

The objective of this study was to compare the healing of the augmented sinus at which the antrostomy was covered with a membrane or the repositioned bone plate. Eight sheep underwent bilateral maxillary sinus floor augmentation. The control site was covered with a resorbable membrane, while at the experimental site the bone plate was repositioned, and both were secured with cyanoacrylate. Animal...

Table 5 Summary of OHIP-14 (N = 44 and respons...

OHIP domainMinimumMaximumMeanSDFunctional limitation072.341.70Physical pain071.161.51Psychological discomfort081.642.27Physical disability080.751.77Psychological disability081.182.11Social disability080.611.40Handicap080.701.71Total0648.49.7Table 5 Summary of OHIP-14 (N = 44 and response range 0–8)

Table 4 Correlation analyses : Patient experience ...

Outcome variablesCorrelationsSpearman’s rhoP valueOHRQoLOral health compared0.596

Table 3 Patient-reported outcomes : Patient experi...

QuestionResponseFrequencyOral healthVery good/good81.8%Quality of LifeVery good/good90.9%General healthVery good/good81.8%Pain after hip operationExcessive35.0%Satisfaction hip operationVery85.7%Post op infection in hip siteNo95.3%Visible scar on hipYes48.8%Acceptable scarYes20 of 21aReduced sensibility on hip siteNo86.0%Problem walkingNo92.9%Augmented bone block still presentNo6.8%New augmentatio...

Table 2 Patients’ demographic and lifestyle-rela...

VariableFrequencyN or Mean ± SD%Patients Female2454.5 Male2045.5Age (years)61.16 ± 13.10 Age at operation53.73 ± 13.07 Time from augmentation to completing questionnaire (months)93.55 ± 31.75 Civil status Married3068.2 Single1125.0 Widow(er)36.8Housing Alone1227.3 With another person2352.3 > two persons920.5Education Up to primary711.3 Up to secondary23...

Table 1 Summary of questions : Patient experience ...

CategoryResponseQuestion (1) Perceived health-status  General health“Very good” to “bad”  Oral health“Very good” to “bad”  Overall quality of life“Excellent” to “bad” (2) Lifestyle-related  Smoking“Yes,” “no,” or “sometimes”  Appetite“Good” to “bad” (3) Donor site-related  Pain“Yes” and “no”  Infection“Yes” a...

About this article : Patient experience following ...

Gjerde, C.G., Shanbhag, S., Neppelberg, E. et al. Patient experience following iliac crest-derived alveolar bone grafting and implant placement. Int J Implant Dent 6, 4 (2020). https://doi.org/10.1186/s40729-019-0200-8 Download citation Received: 10 October 2019 Accepted: 11 December 2019 Published: 05 February 2020 DOI: https://doi.org/10.1186/s40729-019-0200-8

Rights and permissions : Patient experience follow...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were ...

Supplementary information : Patient experience fol...

A self-administered questionnaire.

Additional information : Patient experience follow...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Patient experience following...

The Ethics Committee was contacted in 2015, and no ethical approval was needed since this was then considered a quality control study. Written consent was obtained from all participants. Not applicable. Cecilie G Gjerde, Siddharth Shanbhag, Evelyn Neppelberg, Kamal Mustafa, and Harald Gjengedal declare that they have no competing interests.

Author information : Patient experience following ...

Correspondence to Cecilie G. Gjerde.

Author information : Patient experience following ...

Department of Oral and Maxillofacial Surgery, Institute of Clinical Dentistry, University of Bergen, Årstadveien 19, 5009, Bergen, Norway Cecilie G. Gjerde & Evelyn Neppelberg Centre for Clinical Dental Research, Institute of Clinical Dentistry, University of Bergen, Bergen, Norway Cecilie G. Gjerde, Siddharth Shanbhag & Kamal Mustafa Department of Oral and Maxillofacial Surgery, Head an...

Funding : Patient experience following iliac crest...

This work was partially funded by the Research Council of Norway through the BEHANDLING project (grant no. 273551) and TROND MOHN Foundation, Norway (BFS2018TMT10).

Acknowledgements : Patient experience following il...

The staff and surgeons at the Department of Oral and Maxillofacial Surgery, Head and Neck Clinic, Haukeland University Hospital, Bergen. Randi Aursland, master student, who helped collecting data. The patients included in this study.

References : Patient experience following iliac cr...

Landes CA, Bundgen L, Laudemann K, Ghanaati S, Sader R. Patient satisfaction after prosthetic rehabilitation of bone-grafted alveolar clefts with nonsubmerged ITI Straumann dental implants loaded at three months. Cleft Palate Craniofac J. 2012;49(5):601–8. Reisine S, Freilich M, Ortiz D, Pendrys D, Shafer D, Taxel P. Quality of life improves among post-menopausal women who received bone augment...

References : Patient experience following iliac cr...

Locker D, Allen F. What do measures of ‘oral health-related quality of life’ measure? Community Dent Oral Epidemiol. 2007;35(6):401–11. Sischo L, Broder HL. Oral health-related quality of life: what, why, how, and future implications. J Dent Res. 2011;90(11):1264–70. Slade GD. Assessing change in quality of life using the Oral Health Impact Profile. Community Dent Oral Epidemiol. 1998;26...

References : Patient experience following iliac cr...

Hill NM, Horne JG, Devane PA. Donor site morbidity in the iliac crest bone graft. Aust N Z J Surg. 1999;69(10):726–8. Finkemeier CG. Bone-grafting and bone-graft substitutes. J Bone Joint Surg Am. 2002;84-A(3):454–64. Hernigou P, Desroches A, Queinnec S, Flouzat Lachaniette CH, Poignard A, Allain J, et al. Morbidity of graft harvesting versus bone marrow aspiration in cell regenerative thera...

References : Patient experience following iliac cr...

Schaaf H, Lendeckel S, Howaldt HP, Streckbein P. Donor site morbidity after bone harvesting from the anterior iliac crest. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(1):52–8. Sakkas A, Wilde F, Heufelder M, Winter K, Schramm A. Autogenous bone grafts in oral implantology-is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J I...

Abbreviations : Patient experience following iliac...

Health-related quality of life Oral Health Impact Profile-14 Oral health-related quality of life Patient-reported outcome measures Quality of life

Availability of data and materials : Patient exper...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Patient experience following iliac c...

Favorable OHRQoL and satisfaction were reported after advanced reconstruction with iliac crest-derived grafts and implant treatment in orally compromised patients. However, this treatment requires substantial resources including hospitalization and sick leave.

Discussion : Patient experience following iliac cr...

Patients in our study reported satisfaction with the augmentation and implant installation, and as these patients were orally compromised before the operation, their satisfaction with getting fixed teeth most likely improved their perceived oral health condition. This might also, in part, explain why they reported good OHRQoL. Thus, our findings indicate that a majority of patients tolerate the au...

Discussion : Patient experience following iliac cr...

An important finding in this study is that a majority of patients were very satisfied after iliac crest-derived alveolar bone grafting and implant therapy. Although 90% of the patients in our study had successful bone grafting, only 70.1% reported implant survival together with prosthetic rehabilitation after 1 year. These figures are lower than those reported in previous studies [2, 3, 9]. A rev...

Results : Patient experience following iliac crest...

The correlation analyses performed did not show a significant correlation between the complications at the donor site and implant loss (Table 4). The mean OHIP-14 score (Table 5) was 8.4 ± 9.7 (range 0–56) in 44 patients of whom 35 patients scored 14 or less. Nine patients scored a total sum of 1 [1], i.e. “hardly ever” impact on any single item and “at no time” on the remaining ...

Results : Patient experience following iliac crest...

The final sample consisted of 44 patients that responded and completed the questionnaire, giving a response rate of 74.6%: 24 women and 20 men, mean age of 61.2 years ± 13.1 (range 27–82 years). The mean time from augmentation surgery until completing the questionnaire was 7.8 years ± 2.65 (range 1.9–12 years). Summary of demographic and lifestyle-related data is presented (Tabl...

Methods : Patient experience following iliac crest...

Implants were placed 4–6 months after the grafting procedure. The implant installations were performed by different oral surgeons (not in the hospital) and different implant systems were used. The implants installed into the augmented bone were allowed to heal for an additional 4–6 months before loading. The records of the original 69 patients were examined with regard to (1) grafting sit...

Methods : Patient experience following iliac crest...

This cross-sectional retrospective cohort study was based on records from all patients (n = 69) who underwent advanced alveolar augmentation with autologous iliac bone grafts at the Department of Oral and Maxillofacial Surgery, Haukeland University Hospital, Bergen, Norway, over 10 years (2002–2012). These patients were orally compromised with severe chewing problems as well as speech diff...

Background : Patient experience following iliac cr...

Health-related QoL (HRQoL) is a dynamic concept referring to an individual’s subjective assessment and perspective of current general health condition as well as functional, social, and emotional well-being [23, 24]. Most people regard oral health as important for QoL, and this is mediated through the concept of oral health-related QoL (OHRQoL) [25]. In this regard, OHRQoL is an important PROM i...

Background : Patient experience following iliac cr...

Insufficient alveolar bone volume, as a result of periodontal disease, trauma, congenital anomalies and/or resorption atrophy, often presents a clinical challenge for optimal placement of dental implants for prosthetic rehabilitation. In such cases, augmentation of alveolar bone, with either autologous bone, allogeneic, xenogeneic, or alloplastic biomaterials, is a prerequisite for placing implant...

Abstract : Patient experience following iliac cres...

The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment in orally compromised patients. This cross-sectional retrospective cohort study included 59 patients (29 women and 30 men) with major functional problems, who underwent advanced alveolar augm...

Fig. 6. Graph representing new bone and composite ...

Fig. 6. Graph representing new bone and composite bone percentages within the elevated area Fig. 6. Graph representing new bone and composite bone percentages within the elevated area

Fig. 5. Graph representing the tissue percentages ...

Fig. 5. Graph representing the tissue percentages within the elevated area. No statistically significant differences were found Fig. 5. Graph representing the tissue percentages within the elevated area. No statistically significant differences were found

Fig. 4. Photomicrographs of ground sections after ...

Fig. 4. Photomicrographs of ground sections after 4 months of healing. a Bone formed from the base of the sinus. b Bone plate connected by bridges of the new bone to the close-to-window region. c Particle of the graft surrounded by new bone. d Overexposed image to show the new bone ingrowth within the granules of biomaterial Fig. 4. Photomicrographs of ground sections after 4 months of he...

Fig. 3. a The elevated area was divided into four ...

Fig. 3. a The elevated area was divided into four regions for morphometric analysis. RED: submucosa; GREEN: middle; YELLOW: base; PURPLE: close-to-window. INC: top of the infraorbital nerve canal Fig. 3. a The elevated area was divided into four regions for morphometric analysis. RED: submucosa; GREEN: middle; YELLOW: base; PURPLE: close-to-window. INC: top of the infraorbital nerve canal

Fig. 2. Clinical view at a bone plate site. a The ...

Fig. 2. Clinical view at a bone plate site. a The bone window was removed. b The sinus mucosa was carefully elevated, and a twisted wire was placed. c The elevated sinus was grafted. d The access bony window was repositioned and secured with cyanoacrylate Fig. 2. Clinical view at a bone plate site. a The bone window was removed. b The sinus mucosa was carefully elevated, and a twisted wire wa...

Fig. 1. Clinical view at a membrane site. a Skin a...

Fig. 1. Clinical view at a membrane site. a Skin and periosteum were separately elevated, and the facial sinus wall exposed. b A 12 × 8-mm window was cut and removed. c The Schneiderian membrane was carefully elevated. d A twisted wire was inserted in the middle of the long side of the window and the elevated sinus was grafted. e At the control site, a resorbable membrane was placed and secured...

Table 2 Percentages of various tissues in the antr...

 BoneSoft tissuePure graftInterpenetrated graftComposite boneReplaced windowCenter61.5 ± 46.982.5 (22.2; 96.9)21.7 ± 22.6*17.5 (3.1; 34.4)2.3 ± 4.3*0.0 (0.0; 2.3)7.9 ± 19.30.0 (0.0; 0.0)69.3 ± 38.582.5 (57.6; 96.9)Edge37.2 ± 37.021.6 (16.8; 55.8)41.0 ± 39.833.6 (9.2; 64.9)5.3 ± 7.31.6 (0.0; 9.1)13.8 ± 19.0*6.7 (0.0; 19.7)54.8 ± 34.162.9 (37.5; 69.7)MembraneCenter5.8 ± 2.1 (P = 0.116)5....

Table 1 Percentages of the various tissues within ...

 New boneSoft tissuePure graftInterpenetrated graftComposite boneReplaced windowTotal16.4 ± 5.618.8 (13.8; 20.3)32.9 ± 8.031.2 (27.7; 37.0)13.6 ± 4.212.0 (10.8; 16.2)37.1 ± 7.534.4 (31.7; 43.4)53.5 ± 7.652.4 (50.8; 57.8)Base15.0 ± 7.216.4 (10.1; 20.1)38.6 ± 14.334.5 (28.9; 47.1)13.4 ± 6.415.3 (13.1; 17.0)33.1 ± 11.133.1 (26.8; 40.0)48.0 ± 18.149.9 (36.9; 59.7)Middle16.9 ± 7.318.1 (11.2...

About this article : Bone plate repositioned over ...

Perini, A., Ferrante, G., Sivolella, S. et al. Bone plate repositioned over the antrostomy after sinus floor elevation: an experimental study in sheep. Int J Implant Dent 6, 11 (2020). https://doi.org/10.1186/s40729-020-0207-1 Download citation Received: 01 October 2019 Accepted: 04 February 2020 Published: 18 March 2020 DOI: https://doi.org/10.1186/s40729-020-0207-1

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Ethics declarations : Bone plate repositioned over...

The research protocol was submitted to and approved by the Ethical Committee of the University of Medical Sciences, School of Dentistry, Havana, Cuba (prot. 013/2013). All the authors consent to publication. Alessandro Perini, Giada Ferrante, Stefano Sivolella, Joaquín Urbizo Velez, Franco Bengazi, and Daniele Botticelli declare that they have no competing interests.

Author information : Bone plate repositioned over ...

Correspondence to Alessandro Perini.

Author information : Bone plate repositioned over ...

Department of Neuroscience, Division of Dentistry, University of Padua, Via Giustiniani 2, 35128, Padua, Italy Alessandro Perini, Giada Ferrante & Stefano Sivolella Faculty of Dentistry, University of Medical Science, Havana, Cuba Joaquín Urbizo Velez & Franco Bengazi ARDEC Academy, Ariminum Odontologica, Rimini, Italy Daniele Botticelli You can also search for this author in ...

Funding : Bone plate repositioned over the antrost...

This study was funded by ARDEC Academy, Ariminum Odontologica s.r.l., Rimini, Italy. Degradable Solutions AG, a Sunstar Group Company, CH-8952 Schlieren ZH, Switzerland, provided free of charge the biomaterials used.

Acknowledgements : Bone plate repositioned over th...

Not applicable

References : Bone plate repositioned over the antr...

Iida T. Carneiro Martins Neto E, Botticelli D, Apaza Alccayhuaman KA, Lang NP, Xavier SP. Influence of a collagen membrane positioned subjacent the sinus mucosa following the elevation of the maxillary sinus: a histomorphometric study in rabbits. Clin Oral Implants Res. 2017 Dec;28(12):1567–76. Inal S, Yilmaz N, Nisbet C, Güvenç T. Biochemical and histopathological findings of N-butyl-2-cyano...

References : Bone plate repositioned over the antr...

Russell WMS, Burch RL. The principles of human experimental technique. London: Methuen; 1959. Schroeder HE, Münzel-Pedrazzoli S. Correlated morphometric and biochemical analysis of gingival tissue: morphometric model, tissue sampling and test of stereologic procedures. J Microsc. 1973 Dec;99(3):301–29. Sohn DS, Kim WS, An KM, Song KJ, Lee JM, Mun YS. Comparative histomorphometric analysis of ...

References : Bone plate repositioned over the antr...

Nosaka Y, Nosaka H, Arai Y. Complications of postoperative swelling of the maxillary sinus membrane after sinus floor augmentation. J Oral Sci Rehab. 2015;1:26–33. Tawil G, Tawil P, Khairallah A. Sinus floor elevation using the lateral approach and bone window repositioning I: clinical and radiographic results in 102 consecutively treated patients followed from 1 to 5 years. Int J Oral Maxillof...

References : Bone plate repositioned over the antr...

Tatum H Jr. Maxillary sinus grafting for endosseous implants. Lecture presented at the Annual Meeting of the Alabama Implant Study Group (1977); cited in Smiler DG, Johnson PW, Lozada JL, Misch C, Rosenlicht JL, Tatum OH Jr., Wagner JR. Sinus lift grafts and endosseous implants. Treatment of the atrophic posterior maxilla. Dent Clin North Am. 1992;36:151–86. Boyne PJ, James RA. Grafting of the ...

Abbreviations : Bone plate repositioned over the a...

Biphasic calcium phosphate Deproteinized Bovine Bone Mineral Hydroxyapatite Infraorbital nerve canal Standard deviation Beta-tricalcium phosphate

Availability of data and materials : Bone plate re...

All data and materials are available for control and consultation contacting the first author (alexperini@studioschweiger.it).

Conclusion : Bone plate repositioned over the antr...

In conclusion, the repositioning of the bone window after sinus floor elevation in sheep, compared with the use of a resorbable membrane, improved the closure of the antrostomy and led to a greater amount of the newly formed bone in the close-to-window zone of the grafted area. The bone window appeared partially bonded to the newly formed bone. Bridges of new bone from the edges of the antrostomy ...

Discussion : Bone plate repositioned over the antr...

In the present study, a lesser amount of bone was registered subjacent to the sinus mucosa compared with the other regions. This is in agreement with another experiment, in which a similar material was used for sinus augmentation in sheep [24]. A similar outcome was also reported in another study [27] that used DBBM xenograft for sinus augmentation in sheep. In that study, a collagen membrane was ...

Discussion : Bone plate repositioned over the antr...

In another similar experiment in sheep, the sinuses were augmented using a similar biphasic calcium phosphate (60% HA, 40% β-TCP) [24], the biomaterial used in the present study. The perforation of the sinus mucosa was performed at the test sites and a collagen membrane was placed to protect the perforation, while at control sites the elevated mucosa was left unprotected. After 12 weeks of heal...

Discussion : Bone plate repositioned over the antr...

The aim of the present study was to compare the healing of the augmented sinus in large animals, where the antrostomy was covered by a polylactic membrane or a repositioned bone plate, both secured with cyanoacrylate. No statistically significant differences were found between test and control sites in the bone formation within the augmented space. This outcome is in agreement with a similar stud...

Results : Bone plate repositioned over the antrost...

In the centre of the window area, at the test sites, in the analysed histological sections, the bone plate was still visible in five out of six sheep. It appeared partly remodelled and connected by the new bone formed in the sub-window area. Out of the five bone plates still present, three were bridged to the edges of the antrostomy, while in the two cases no contact was achieved in the observed s...

Results : Bone plate repositioned over the antrost...

During surgery, one sheep showed acute sinusitis at the test site. The sinus mucosa was perforated to allow sinus drainage and surgery was completed. During the healing period, no evident clinical complications were observed. At the histomorphometric analysis, one sinus of the control group and one of the test group (corresponding to the sinusitis case) appeared to have lost almost all biomateria...

Materials and methods : Bone plate repositioned ov...

The percentages of the new mineralised bone, soft or connective tissue, pure graft, graft interpenetrated by bone, and remnants of cyanoacrylate were evaluated. The total tissue percentages in the elevated space that included submucosa, middle, base, and sub-window regions were also calculated. Mean values and standard deviations (SDs) as well as the 25th, 50th (median), and 75th percentiles were...

Materials and methods : Bone plate repositioned ov...

After 4 months, the animals were anaesthetised and then euthanised with an overdose of pentobarbital sodium and subsequently perfused with 10% formalin. The maxilla was retrieved en bloc, trimmed, and immersed in formalin solution. All histological procedures were performed in the Laboratorio de Histologıa de la Facultad de Odontologıa de la Universidad de Ciencia Medica in Havana, Cuba. Bila...

Materials and methods : Bone plate repositioned ov...

Through an extra-oral approach, an oblique incision was made bilaterally along the sagittal axis between the facial tuberosity and the inferior orbital rim. The skin and periosteum were elevated separately, and the bony facial sinus wall was exposed on both sides of the maxilla (Fig. 1a). A 12-mm large and 8-mm high antrostomy was prepared using a burr (H254E Komet Dental, Trophagener Weg 25, L...

Materials and methods : Bone plate repositioned ov...

The research protocol was submitted to and approved by the Ethical Committee of the University of Medical Sciences, School of Dentistry, Havana, Cuba (prot. 013/2013). Eight female Pelibuey sheep, with a mean body weight of approximately 35 kg and a mean age of approximately 3 years, were provided by the Centro Nacional para la Producción de Animales de Laboratorio (CENPALAB) in Havana, Cuba...

Introduction : Bone plate repositioned over the an...

To prevent the movement of the bony plate and to gain adequate stability, cyanoacrylate has been suggested to glue the plate to the bony edges of the antrostomy [17]. Cyanoacrylates (as methyl 2-cyanoacrylate or ethyl 2-cyanoacrylate) are widely used in surgery and have shown good compatibility [18] and biomechanical strength for fixation of grafts [19]. In an experiment in rabbits [17], the antro...

Introduction : Bone plate repositioned over the an...

Sinus floor elevation is a commonly used technique to increase bone volume in the posterior maxilla prior to implant placement. This procedure was first developed by Tatum in 1977 [1], modified by Boyne and James in 1980 [2], and further modified over time. In this well-described technique, a bony window is created on the lateral wall of the sinus with a round burr, and the membrane elevated. Diff...

Abstract : Bone plate repositioned over the antros...

The objective of this study was to compare the healing of the augmented sinus at which the antrostomy was covered with a membrane or the repositioned bone plate. Eight sheep underwent bilateral maxillary sinus floor augmentation. The control site was covered with a resorbable membrane, while at the experimental site the bone plate was repositioned, and both were secured with cyanoacrylate. Animal...

Table 1 Implant characteristics—insertion region...

Patient Implant region (FDI) Implant parameters Dimensions of implant Diameter [mm]/length [mm] ...

About this article : Vitamin D deficiency in early...

Fretwurst, T., Grunert, S., Woelber, J.P. et al. Vitamin D deficiency in early implant failure: two case reports. Int J Implant Dent 2, 24 (2016). https://doi.org/10.1186/s40729-016-0056-0 Download citation Received: 04 August 2016 Accepted: 16 November 2016 Published: 25 November 2016 DOI: https://doi.org/10.1186/s40729-016-0056-0

Rights and permissions : Vitamin D deficiency in e...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Vitamin D deficiency in early...

Department of Oral- and Craniomaxillofacial Surgery, Center for Dental Medicine, University Medical Center Freiburg, Hugstetter Straße 55, Freiburg, D-79106, Germany Tobias Fretwurst, Sebastian Grunert, Katja Nelson & Wiebke Semper-Hogg Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, USA Tobias Fretwurst Department of Operative Dentistr...

Acknowledgements : Vitamin D deficiency in early i...

We would like to thank Dr. John Nelson for his resourceful and constructive ideas. The authors Tobias Fretwurst, Sebastian Grunert, Johan Woelber, Katja Nelson, and Wiebke Semper-Hogg declare no conflicts of interest with respect to the research, authorship, and/or publication of this article. The authors Tobias Fretwurst, Sebastian Grunert, Johan Woelber, Katja Nelson, and Wiebke Semper-Hogg do...

References : Vitamin D deficiency in early implant...

Di Rosa M, Malaguarnera M, Nicoletti F, Malaguarnera L. Vitamin D3: a helpful immuno-modulator. Immunology. 2011;134(2):123–39. Download references

References : Vitamin D deficiency in early implant...

Kikuta J, Kawamura S, Okiji F, Shirazaki M, Sakai S, Saito H, Ishii M. Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D. Proc Natl Acad Sci U S A. 2013;110(17):7009–13. Hewison M, Freeman L, Hughes SV, Evans KN, Bland R, Eliopoulos AG, Kilby MD, Moss PA, Chakraverty R. Differential regulatio...

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Hong HH, Chou TA, Yang JC, Chang CJ. The potential effects of cholecalciferol on bone regeneration in dogs. Clin Oral Implants Res. 2012;23(10):1187–92. Hong HH, Yen TH, Hong A, Chou TA. Association of vitamin D3 with alveolar bone regeneration in dogs. J Cell Mol Med. 2015;19(6):1208–17. Schulze-Späte U, Dietrich T, Wu C, Wang K, Hasturk H, Dibart S. Systemic vitamin D supplementation and ...

References : Vitamin D deficiency in early implant...

Gallagher JC, Sai AJ. Vitamin D insufficiency, deficiency, and bone health. J Clin Endocrinol Metab. 2010;95(6):2630–3. Ning Z, Song S, Miao L, Zhang P, Wang X, Liu J, Hu Y, Xu Y, Zhao T, Liang Y, Wang Q, Liu L, Zhang J, Hu L, Huo M, Zhou Q. High prevalence of vitamin D deficiency in urban health checkup population. Clin Nutr. 2016;35(4):859–63. Spiro A, Buttriss JL. Vitamin D: an overview o...

References : Vitamin D deficiency in early implant...

Maier GS, Horas K, Seeger JB, Roth KE, Kurth AA, Maus U. Is there an association between periprosthetic joint infection and low vitamin D levels? Int Orthop. 2014;38(7):1499–504. Alvim-Pereira F, Montes CC, Thomé G, Olandoski M, Trevilatto PC. Analysis of association of clinical aspects and vitamin D receptor gene polymorphism with dental implant loss. Clin Oral Implants Res. 2008;19(8):786–...

References : Vitamin D deficiency in early implant...

Esposito M, Thomsen P, Ericson LE, Lekholm U. Histopathologic observations on early oral implant failures. Int J Oral Maxillofac Implants. 1999;14:798–810. Olmedo-Gaya MV, Manzano-Moreno FJ, Cañaveral-Cavero E, de Dios Luna-Del Castillo J, Vallecillo-Capilla M. Risk factors associated with early implant failure: a 5-year retrospective clinical study. J Prosthet Dent. 2016;115(2):150–5. Wenn...

Conclusions : Vitamin D deficiency in early implan...

To overcome the shortcomings of this case reports, prospective, multicenter, and controlled studies must follow to affirm a potential relationship between vitamin D deficiency, osteoimmunology, and the early failure of dental implants. Currently, a general recommendation for a standardized vitamin D screening in dental implantology cannot be stated due to lack of evidence.

Case presentation : Vitamin D deficiency in early ...

Nevertheless, the vitamin D deficiency prevalence in the European population indicates that a vitamin D deficiency is probably not a sole causative factor for early implant failure; otherwise, the early implant failure rate would be significantly higher. However, a synergistic effect with other factors is conceivable. Some authors stated that implant osseointegration is not simply a wound healing ...

Case presentation : Vitamin D deficiency in early ...

Local and systemic factors can affect the survival rate of dental implants [30–33]. The causes of early implant failure are not fully clarified and an association between vitamin D and dental implant osseointegration has not been investigated properly [8, 13–16]. Some recent animal studies in rodents demonstrated a relationship between vitamin D supplementation and an increased bone to implant...

Case presentation : Vitamin D deficiency in early ...

In this 51-year-old male patient, no grafting procedure was performed as vertical and horizontal alveolar ridge dimension was adequate for implant placement. The implant placement in regions 36 and 37 was performed as guided surgery (Fig. 2a, Table 1). The implant placement was uneventful and the bone appeared clinically healthy. A cortical bone profiling was performed during implant placement. ...

Case presentation : Vitamin D deficiency in early ...

The medical history of this 48-year-old male patient showed a high blood pressure; otherwise, the patient was healthy. A successfully completed periodontal therapy was done before implant therapy. The patient demonstrated stable marginal bone levels. Autologous retromolar bone grafting using local anesthesia was performed in the left mandible (see Fig. 1a). This patient received a postoperative o...

Case presentation : Vitamin D deficiency in early ...

Patients treated consecutively in one center (Department of Oral- and Craniomaxillofacial Surgery, University Medical Center Freiburg). None of the patients showed systemic disease. Both patients did not take regular medication and were negative for alcohol, nicotine, and drug use. Bothe male patients (48 and 51 years of age) were not immunosuppressed, irradiated or received chemotherapy. Written...

Background : Vitamin D deficiency in early implant...

Long-term stable osseointegrated implants are the primary goal in dental implantology. Although dental implants have proven clinical reliable in the long term, the failure of implants at a very early stage of osseointegration has been described [1, 2]. The pursuit to identify the mechanisms leading to early implant failure is ongoing to date and include the following: tobacco usage, diabetes, wear...

Abstract : Vitamin D deficiency in early implant f...

An association between vitamin D deficiency and early dental implant failure is not properly verified, but its role in osteoimmunology is discussed. This article illustrates two case reports with vitamin D deficiency and early implant failure. Prior to implant placement, the first patient received crestal bone grafting with autologous material. Both patients received dental implants from different...

Fig. 7. Nine-year follow-up radiograph of the impl...

Fig. 7. Nine-year follow-up radiograph of the implants Fig. 7. Nine-year follow-up radiograph of the implants

Fig. 6. Application of final fixed prosthesis : Sa...

Fig. 6. Application of final fixed prosthesis Fig. 6. Application of final fixed prosthesis

Fig. 5. Plate removal and insertion of two implant...

Fig. 5. Plate removal and insertion of two implants 6 months after grafting Fig. 5. Plate removal and insertion of two implants 6 months after grafting

Fig. 4. Preoperative and postoperative radiograph ...

Fig. 4. Preoperative and postoperative radiograph Fig. 4. Preoperative and postoperative radiograph

Fig. 3. a A paracrestal incision was made on the b...

ed Fig. 3. a A paracrestal incision was made on the buccal side, and horizontal and vertical osteotomies were made with a piezo-electric device. b Placement of the ramus bone block as an interpositional graft. c Ramus bone graft fixed

Fig. 2. Septa and thickened sinus membrane within ...

Fig. 2. Septa and thickened sinus membrane within maxillary sinus Fig. 2. Septa and thickened sinus membrane within maxillary sinus

Fig. 1. Preoperative intraoral photograph and radi...

Fig. 1. Preoperative intraoral photograph and radiograph Fig. 1. Preoperative intraoral photograph and radiograph

About this article : Sandwich bone graft for verti...

Tanaka, K., Sailer, I., Kataoka, Y. et al. Sandwich bone graft for vertical augmentation of the posterior maxillary region: a case report with 9-year follow-up. Int J Implant Dent 3, 20 (2017). https://doi.org/10.1186/s40729-017-0063-9 Download citation Received: 15 October 2016 Accepted: 13 January 2017 Published: 19 May 2017 DOI: https://doi.org/10.1186/s40729-017-0063-9

Rights and permissions : Sandwich bone graft for v...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Sandwich bone graft for verti...

Division of Oral and Maxillofacial Surgery, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Miyagi, Japan Kenko Tanaka, Yoshihiro Kataoka, Shinnosuke Nogami & Tetsu Takahashi Division of Fixed Prosthodontics and Biomaterials Clinic of Dental Medicine, University of Geneva, 19 rue Barthélemy-Menn, CH-1205, ...

Acknowledgements : Sandwich bone graft for vertica...

The authors thank Atumu Kouketu for his figure illustration support and Kouhei Shinmyouzu for the clinical support. Authors Kenko Tanaka, Irena Sailer, Yoshihiro Kataoka, Shinnosuke Nogami, and Tetsu Takahashi declare that they have no competing interests.

References : Sandwich bone graft for vertical augm...

Download references

References : Sandwich bone graft for vertical augm...

Thoma DS, Zeltner M, Hüsler J, Hämmerle CH, Jung RE, EAO Supplement Working Group 4 - EAO CC. Short implants versus sinus lifting with longer implants to restore the posterior maxilla: a systematic review. Clin Oral Implants Res. 2015;26:154–169. Lee SA, Lee CT, Fu MM, Elmisalati W, Chuang SK. Systematic review and meta-analysis of randomized controlled trials for the management of limited ve...

References : Sandwich bone graft for vertical augm...

Adell R, Brånemark PI. A 15-year study of osseointegrated implant in the treatment of the edentulous jaw. Int J Oral Maxillofac Surg. 1981;10:387–416. Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986;1:11–25. Cordo L, Terheyden H. ITI treatment guide vo...

Conclusions : Sandwich bone graft for vertical aug...

We described in the present case a vertical lack of the bone from the alveolar ridge to the opposing teeth, the short distance from the reabsorbed ridge to the floor of the maxillary sinus, and the presence of septa and a thickened sinus membrane within the maxillary sinus. A sandwich bone graft was successfully applied and followed up in the long term. The resulting gains in ridge height and incr...

Discussion : Sandwich bone graft for vertical augm...

In this case, the alveolar ridge was Seibert class II, and septa and a thickened sinus membrane were evident within the maxillary sinus. Sinus floor elevation was limited because of the condition of the floor morphology, the presence of septa, and the thickness of sinus floor membrane [22, 23]. Considering these issues, we selected the interpositional bone graft technique using autologous bone in ...

Discussion : Sandwich bone graft for vertical augm...

This paper reports on a segmental osteotomy procedure with an interpositional graft in the posterior maxillary region with 9 years of follow-up. The techniques used to overcome a lack of alveolar bone height rely on the placement supplemented by various vertical guided bone regeneration (GBR) procedures [4, 5] and the use of alveolar distraction osteogenesis [6], titanium mesh [7], or onlay bone...

Case presentation : Sandwich bone graft for vertic...

Six months after surgery, radiological examinations were carried out and the patient underwent implant placement (Fig. 4). The postoperative bone height had increased to 10.1 mm at position 26 and 12.9 mm at position 27 compared with the preoperative heights of 6.1 and 7.5 mm, respectively. Postoperative clearance was reduced by 11 mm compared with the preoperative clearance. Careful separati...

Case presentation : Sandwich bone graft for vertic...

A 67-year-old male patient sought implant rehabilitation for the purposes of restoration of occlusal support and assistance with chewing difficulties. Clinical and radiological examinations revealed that teeth were absent 26–27. The clearance from the alveolar ridge to the opposing teeth was 20 mm (Fig. 1). A CT scan showed that the distance from the reabsorbed ridge to the floor of the maxill...

Background : Sandwich bone graft for vertical augm...

In the literature, the technique of segmental osteotomy accompanied by interpositional grafting has been reported as a practical and predictable procedure with a low incidence of complications and a high probability of success [15,16,17,18,19]. This approach leaves the soft tissue on the oral side of the midcrestal incision attached to the crestal bone segment. Various studies have shown that alve...

Background : Sandwich bone graft for vertical augm...

Osseointegrated implants for the replacement of missing teeth have recently become a routine treatment option [1, 2]. However, any tooth loss may be followed by extensive resorption of the alveolar ridge, which usually makes implant placement difficult or impossible because of the lack of bone volume. There are a variety of defect situations with increasing complexity, ranging from fenestrations, ...

Abstract : Sandwich bone graft for vertical augmen...

The loss of teeth followed by bone resorption often lead to defects in the alveolar ridge, making installation of dental implants difficult. Correction of such bone defects, especially lack of height of the ridge, is a difficult problem for all dental surgeons. This report describes the outcome of treatment after alveolar ridge augmentation in the atrophic posterior maxillary region via segmental ...

About this article : Sandwich bone graft for verti...

Tanaka, K., Sailer, I., Kataoka, Y. et al. Sandwich bone graft for vertical augmentation of the posterior maxillary region: a case report with 9-year follow-up. Int J Implant Dent 3, 20 (2017). https://doi.org/10.1186/s40729-017-0063-9 Download citation Received: 15 October 2016 Accepted: 13 January 2017 Published: 19 May 2017 DOI: https://doi.org/10.1186/s40729-017-0063-...

Rights and permissions : Sandwich bone graft for v...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Sandwich bone graft for verti...

Division of Oral and Maxillofacial Surgery, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Miyagi, Japan Kenko Tanaka, Yoshihiro Kataoka, Shinnosuke Nogami & Tetsu Takahashi Division of Fixed Prosthodontics and Biomaterials Clinic of Dental Medicine, University of Geneva, 19 rue Barthélemy-Menn, CH-1205, ...

Acknowledgements : Sandwich bone graft for vertica...

The authors thank Atumu Kouketu for his figure illustration support and Kouhei Shinmyouzu for the clinical support. Authors Kenko Tanaka, Irena Sailer, Yoshihiro Kataoka, Shinnosuke Nogami, and Tetsu Takahashi declare that they have no competing interests.

References : Sandwich bone graft for vertical augm...

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References : Sandwich bone graft for vertical augm...

Thoma DS, Zeltner M, Hüsler J, Hämmerle CH, Jung RE, EAO Supplement Working Group 4 - EAO CC. Short implants versus sinus lifting with longer implants to restore the posterior maxilla: a systematic review. Clin Oral Implants Res. 2015;26:154–169. Lee SA, Lee CT, Fu MM, Elmisalati W, Chuang SK. Systematic review and meta-analysis of randomized controlled trials for the management of limited ve...

References : Sandwich bone graft for vertical augm...

Adell R, Brånemark PI. A 15-year study of osseointegrated implant in the treatment of the edentulous jaw. Int J Oral Maxillofac Surg. 1981;10:387–416. Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986;1:11–25. Cordo L, Terheyden H. ITI treatment guide vo...

Conclusions : Sandwich bone graft for vertical aug...

We described in the present case a vertical lack of the bone from the alveolar ridge to the opposing teeth, the short distance from the reabsorbed ridge to the floor of the maxillary sinus, and the presence of septa and a thickened sinus membrane within the maxillary sinus. A sandwich bone graft was successfully applied and followed up in the long term. The resulting gains in ridge height and incr...

Discussion : Sandwich bone graft for vertical augm...

In this case, the alveolar ridge was Seibert class II, and septa and a thickened sinus membrane were evident within the maxillary sinus. Sinus floor elevation was limited because of the condition of the floor morphology, the presence of septa, and the thickness of sinus floor membrane [22, 23]. Considering these issues, we selected the interpositional bone graft technique using autologous bone in ...

Discussion : Sandwich bone graft for vertical augm...

This paper reports on a segmental osteotomy procedure with an interpositional graft in the posterior maxillary region with 9 years of follow-up. The techniques used to overcome a lack of alveolar bone height rely on the placement supplemented by various vertical guided bone regeneration (GBR) procedures [4, 5] and the use of alveolar distraction osteogenesis [6], titanium mesh [7], or onlay bone...

Case presentation : Sandwich bone graft for vertic...

Six months after surgery, radiological examinations were carried out and the patient underwent implant placement (Fig. 4). The postoperative bone height had increased to 10.1 mm at position 26 and 12.9 mm at position 27 compared with the preoperative heights of 6.1 and 7.5 mm, respectively. Postoperative clearance was reduced by 11 mm compared with the preoperative clearance. Careful separati...

Case presentation : Sandwich bone graft for vertic...

A 67-year-old male patient sought implant rehabilitation for the purposes of restoration of occlusal support and assistance with chewing difficulties. Clinical and radiological examinations revealed that teeth were absent 26–27. The clearance from the alveolar ridge to the opposing teeth was 20 mm (Fig. 1). A CT scan showed that the distance from the reabsorbed ridge to the floor of the maxill...

Background : Sandwich bone graft for vertical augm...

In the literature, the technique of segmental osteotomy accompanied by interpositional grafting has been reported as a practical and predictable procedure with a low incidence of complications and a high probability of success [15,16,17,18,19]. This approach leaves the soft tissue on the oral side of the midcrestal incision attached to the crestal bone segment. Various studies have shown that alve...

Background : Sandwich bone graft for vertical augm...

Osseointegrated implants for the replacement of missing teeth have recently become a routine treatment option [1, 2]. However, any tooth loss may be followed by extensive resorption of the alveolar ridge, which usually makes implant placement difficult or impossible because of the lack of bone volume. There are a variety of defect situations with increasing complexity, ranging from fenestrations, ...

Abstract : Sandwich bone graft for vertical augmen...

The loss of teeth followed by bone resorption often lead to defects in the alveolar ridge, making installation of dental implants difficult. Correction of such bone defects, especially lack of height of the ridge, is a difficult problem for all dental surgeons. This report describes the outcome of treatment after alveolar ridge augmentation in the atrophic posterior maxillary region via segmental ...

Fig. 5. Survival rate of dental implants after aut...

Fig. 5. Survival rate of dental implants after autologous bone augmentation Fig. 5. Survival rate of dental implants after autologous bone augmentation

Fig. 4. Postoperative nerve alterations. Single as...

Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Double asterisk, N refers to the total number of the surgical approaches in the maxilla (N = 225) Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Dou...

Fig. 3. Surgical outcome after autologous augmenta...

Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites

Fig. 2. Survival rate of autologous bone grafts : ...

Fig. 2. Survival rate of autologous bone grafts Fig. 2. Survival rate of autologous bone grafts

Fig. 1. Postoperative complications at the donor a...

Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378) Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378)

Table 3 Intra- and postoperative complications aft...

Postoperative complications %/procedures (N) At donor sitea    Wound infection 2.6% (8/300) At recipient site...

Table 2 Donor sites and numbers of bone grafts as ...

Donor site Bone grafts (N)/patients (N) Lateral zygomatic buttress 113/112 Mandibular ramus (retromolar) ...

Table 1 Patient characteristics at the time of aug...

Patient characteristics N (%) Gendera    Male 250 (89.6%)  Female 29 (10.4%) ...

About this article : Autogenous bone grafts in ora...

Sakkas, A., Wilde, F., Heufelder, M. et al. Autogenous bone grafts in oral implantology—is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J Implant Dent 3, 23 (2017). https://doi.org/10.1186/s40729-017-0084-4 Download citation Received: 27 February 2017 Accepted: 22 May 2017 Published: 01 June 2017 DOI: https://doi...

Rights and permissions : Autogenous bone grafts in...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Autogenous bone grafts in ora...

Department of Oral and Plastic Maxillofacial Surgery, Military Hospital Ulm, Academic Hospital of the University of Ulm, Oberer Eselsberg 40, 89081, Ulm, Germany Andreas Sakkas, Frank Wilde, Marcus Heufelder & Alexander Schramm Institute of Anatomy, Medical Faculty of Leipzig University, Leipzig, Germany Karsten Winter Department of Oral and Plastic Maxillofacial Surgery, University Hospit...

Acknowledgements : Autogenous bone grafts in oral ...

The authors thank the patients for their kindness to participate as study cases and the whole medical team at the Bundeswehrkrankenhaus Ulm. AS participated in its design and coordination, carried out the data selection, and drafted the manuscript, and is the corresponding author. FW participated in its design and coordination and helped in drafting the manuscript. MH participated in its design a...

References : Autogenous bone grafts in oral implan...

Semper W, Kraft S, Mehrhof J, Nelson K. Impact of abutment rotation and angulation on marginal fit: theoretical considerations. Int J Oral Maxillofac Implants. 2010;25:752–8. Wiltfang J, Jätschmann N, Hedderich J, Neukam FW, Schlegel KA, Gierloff M. Effect of deproteinized bovine bone matrix coverage on the resorption of iliac cortico-spongeous bone grafts—a prospective study of two cohorts....

References : Autogenous bone grafts in oral implan...

Chiapasco M, Zaniboni M. Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations: a systematic review. Clin Oral Implants Res. 2009;20:113–23. Felice P, Pellegrino G, Checchi L, Pistilli R, Esposito M. Vertical augmentation with interpositional blocks of anorganic bovine bone vs. 7-mm-long implants in posterior mandibles: 1-year results of a randomized clinical...

References : Autogenous bone grafts in oral implan...

Verdugo F, Castillo A, Moragues MD, Pontón J. Bone microbial contamination influences autogenous grafting in sinus augmentation. J Periodontol. 2009;80:1355–64. Wiltfang J, Schultze-Mosgau S, Merten HA, Kessler P, Ludwig A, Engelke W. Endoscopic and ultrasonographic evaluation of the maxillary sinus after combined sinus floor augmentation and implant insertion. Oral Surg Oral Med Oral Pathol O...

References : Autogenous bone grafts in oral implan...

von Arx T, Buser D. Horizontal ridge augmentation using autogenous block grafts and the guided bone regeneration technique with collagen membranes: a clinical study with 42 patients. Clin Oral Implants Res. 2006;17:359–66. Levin L, Nitzan D, Schwartz-Arad D. Success of dental implants placed in intraoral block bone grafts. J Periodontol. 2007;78:18–21. Andersson L. Patient self-evaluation of...

References : Autogenous bone grafts in oral implan...

Aghaloo TL, Moy PK. Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement? Int J Oral Maxillofac Implants. 2007;22:49–70. Margonar R, dos Santos PL, Queiroz TP, Marcantonio E. Rehabilitation of atrophic maxilla using the combination of autogenous and allogeneic bone grafts followed by protocol-type prosthesis. J Craniofac Surg. 2010;2...

References : Autogenous bone grafts in oral implan...

Schwartz-Arad D, Dori S. Intraoral autogenous onlay block bone grafting for implant dentistry. Refuat Hapeh Vehashinayim. 2002;19:35–9. 77. Misch CM. Ridge augmentation using mandibular ramus bone grafts for the placement of dental implants: presentation of a technique. Pract Periodontics Aesthet Dent. 1996;8:127–35. Altiparmak N, Soydan SS, Uckan S. The effect of conventional surgery and pi...

References : Autogenous bone grafts in oral implan...

Jensen AT, Jensen SS, Worsaae N. Complications related to bone augmentation procedures of localized defects in the alveolar ridge. A retrospective clinical study. Oral Maxillofac Surg. 2016;20(2):115–22 [Epub ahead of print]. Buser D, Dula K, Hirt HP, Schenk RK. Lateral ridge augmentation using autografts and barrier membranes: clinical study with 40 partially edentulous patients. J Oral Maxill...

Conclusions : Autogenous bone grafts in oral impla...

The results of the clinical study proves the reliability and low comorbidity of autologous bone grafts in preprosthetic alveolar ridge reconstructions prior to implant insertion. The high graft success rate (95.6%) and the low early implant failure rate (0.38%) in a surveillance of all patients treated in three following years with this technique showing no exclusion and no dropout of any case for...

Discussion : Autogenous bone grafts in oral implan...

Data on risk factors based on the original examination and documentation are difficult to assess the adverse effects of variable factors on the surgical prognosis because of the multifactorial genesis of surgical complications [73]. Factors such as gender, age, or smoking habit could be associated with postoperative complications after two-stage dentoalveolar reconstruction with autologous bone gr...

Discussion : Autogenous bone grafts in oral implan...

The results of the present study have to take into account the absence of a control group with patients undergoing bone augmentation procedures with bone substitutes (allogen, alloplastic, exogen). Without a comparative group of grafting surgeries using alternative bone material, only limited statements can be made. However, the excellent surgical outcome of autologous surgical methods providing ...

Discussion : Autogenous bone grafts in oral implan...

The use of autologous bone in this study has shown excellent graft survival and success rate (95.6%). This is equal to the results from the studies on implants inserted in reconstructed sites [6, 8, 24]. The early implant survival rate of 99.7% found in the present material is very high comparable to that in the previous systematic reviews after staged horizontal ridge augmentation [9, 10, 22, 62,...

Discussion : Autogenous bone grafts in oral implan...

Of the sinus floor elevations performed in this study, 84.8% were defined absolutely successful. Only two of our 72 patients having sinus lift operations could not finally be treated with dental implants. These results are comparable to other studies considering the sinus graft to be a safe treatment modality with few complications [6, 8, 51,52,53]. Raghoebar et al. reported incidences of sinus co...

Discussion : Autogenous bone grafts in oral implan...

Postoperative morbidity after mandibular bone harvesting procedures was reported to be mainly related to temporary or permanent neural disturbances involving the inferior alveolar nerve and its branches [19]. In this study, only the incidence of the temporary hypoesthesia of the mandibular and lingual nerve after harvesting from the retromolar area could be detected. It was 10.4 and 2.8%, respecti...

Discussion : Autogenous bone grafts in oral implan...

Systematic reviews have failed to find evidence that one particular grafting technique is superior to others [10]. Intraoral bone grafts from the mandibular symphysis, mandibular ramus, and maxillary tuberosity provide a good treatment modality for ridge augmentation, and the amount of bone available for harvesting is sufficient for defects up to the width of three teeth [42]. Harvesting of retrom...

Discussion : Autogenous bone grafts in oral implan...

Several grafting procedures have been described to create sufficient volume of bone for implant placement [8, 9]. Autologous bone grafts can be harvested by an intraoral approach (mandibular ramus, mandibular symphysis, zygomatic buttress) or from distant sites (iliac crest, calvaria, and etc.) [17, 36, 37]. However, bone harvesting potentially causes donor site morbidity which is a major issue fo...

Results : Autogenous bone grafts in oral implantol...

The average healing period until implant placement after bone harvesting was 4.53 months. Initially, 546 implants in 279 patients were planned. After the healing period, it was possible to place 525 implants in 436 successfully augmented areas in 259 patients. Three hundred implants were inserted in the maxilla and 225 in the mandible. The remaining 21 implants planned for 20 patients could not b...

Results : Autogenous bone grafts in oral implantol...

Regarding intraoperative complications, all sinus membrane perforations were covered with a resorbable collagen membrane (Bio-Gide®, Geistlich Biomaterials, Baden-Baden, Germany) which applied as sealant to overlap the site of perforation prior to insertion of the graft material. These patients were advised to avoid physical stress, blowing their noses, or sneezing for a period of 3 weeks, and n...

Results : Autogenous bone grafts in oral implantol...

No permanent damage to any trigeminal nerves was evident in any of our entire cohort. All cases of postoperative hypoesthesia of the mental, lingual, or infraorbital nerve were just a temporary nature. At the time of implant surgery, none of these patients reported any persisting neural disturbances (Fig. 4). In eleven patients, hypoesthesia of the mental area was mentioned, and three of them al...

Results : Autogenous bone grafts in oral implantol...

Thirty-eight patients underwent a total of 116 augmentation procedures harvesting from the iliac crest. In 20 patients, a bone graft augmentation of the maxilla and the mandible in combination with bilateral sinus floor augmentations was performed. Eighteen patients had augmentations only in the maxilla, involving bone grafting and sinus lift elevations. Totally, 76 sinus lifts with bone material ...

Results : Autogenous bone grafts in oral implantol...

In six patients, a partial graft resorption was detected at the time of implantation and an additional simultaneous augmentation with bone chips harvested with the Safescraper device (C.G.M. S.p.A., Divisione Medicale META, Italy) was then necessary in order to ensure the osseointegration of the implants. Two out of these six cases had grafts from the crista zygomatico-alveolaris, two from the ram...

Results : Autogenous bone grafts in oral implantol...

A total of 112 sinus floor elevations were performed. In all of the cases, implants were inserted in a two-stage procedure. The donor site for harvesting the bone for the sinus elevations was in 76 procedures in the iliac crest area, and in 36 procedures, the bone was harvested with a bone scraper device from the lateral sinus wall at the site of sinus lifting. The distribution and number of tran...

Results : Autogenous bone grafts in oral implantol...

Two hundred seventy-nine patients—250 men and 29 women—underwent 456 augmentation procedures involving autologous bone grafts prior to implant placement. The patients ranged in age from 18.5 to 71.5 years (average 43.1 years) at the moment of augmentation surgery. Of those patients, 162 (58.1%) were younger than 40 years of age and 117 (41.9%) were older than 40 years of age. Caries or pe...

Methods : Autogenous bone grafts in oral implantol...

Early and late implant loss was documented in this study, defining the clinical success of osseointegration. Early implant failures were assessed before the acquisition of osseointegration, i.e., before the placement of prosthodontic restorations. Early implant failure could occur from the time of placement, during the healing phase and before abutment connection. The implant inserted after re-aug...

Methods : Autogenous bone grafts in oral implantol...

Medical history of patient Age of patient at the time of bone harvesting and augmentation History of periodontal disease Smoking habits Donor site Jaw area and dental situation of the recipient site Intraoperative complications Postoperative complications after augmentation Management of complications Bone graft stability and clinical resorption prior to implant placement Complications a...

Methods : Autogenous bone grafts in oral implantol...

In addition to the bone already gained with the bone scraper device from the sinus wall during the antrostomy, bone was harvested with the same device from the maxillary buccal buttress, if more volume was needed. By taking this approach, the collection of enough bone for the augmentation of at least two implantation sites was feasible with a mean surgical time of 5 to 10 min for harvesting. In c...

Methods : Autogenous bone grafts in oral implantol...

Grafting from the iliac crest was always performed under general anesthesia in a two-team approach. The iliac crest was exposed and autogenous grafts from the anterosuperior inner edge of the iliac wing were harvested with an oscillating saw and/or a chisel, keeping a safe distance of around 2 cm from the anterosuperior iliac spine. After harvesting the bone grafts, the corticocancellous bone blo...

Methods : Autogenous bone grafts in oral implantol...

A standardized two-stage surgical protocol was used, and all sites were treated in a similar fashion. In the first intervention, a bone block harvested from the donor site was fixed with osteosynthesis titanium screws to the recipient site as an onlay graft to achieve a horizontal and/or vertical enlargement of the alveolar ridge. Placement of the bone graft was always guided by an augmentation te...

Methods : Autogenous bone grafts in oral implantol...

For this retrospective cohort study, we reviewed the records of all patients without exclusion criteria who were referred to the department of oral and plastic maxillofacial surgery at the military hospital of Ulm, Germany, between January 2009 and December 2011 for alveolar ridge augmentations prior to implant insertions using autologous bone grafts harvested from different donor sites and unilat...

Background : Autogenous bone grafts in oral implan...

In our military outpatient center exclusively, autologous bone transplantations harvested from different donor sites were used intraorally (crista zygomatico-alveolaris, ramus mandible, symphysis mandible, anterior sinus wall) and extraorally (iliac crest) to reconstruct severe horizontal and/or vertical alveolar ridge atrophy prior to implant placement. The aim of this study was to assess the cli...

Background : Autogenous bone grafts in oral implan...

Although the iliac crest is most often used in jaw reconstruction, a significant bone resorption has been mentioned [12]. This disadvantage, and the fact that dental implants do not always require a large amount of bone, has increased the use of autologous block bone grafts from intraoral sources [13]. Bone grafts from intraoral donor sites offer several benefits like surgical accessibility, proxi...

Background : Autogenous bone grafts in oral implan...

Oral implantation has a significant role in the rehabilitation of patients. Bone reconstruction techniques have been advanced in order to optimize the esthetic and functional outcome. However, the restoration of the oral function of atrophic alveolar crests still remains a challenge in oral implantology. Bone augmentation procedures are often indicated to allow implant placement in an optimal thre...

Abstract : Autogenous bone grafts in oral implanto...

This review demonstrates the predictability of autologous bone material in alveolar ridge reconstructions prior to implant insertion, independent from donor and recipient site including even autologous bone chips for sinus elevation. Due to the low harvesting morbidity of autologous bone grafts, the clinical results of our study indicate that autologous bone grafts still remain the “gold standar...

Abstract : Autogenous bone grafts in oral implanto...

This study assessed the clinical outcomes of graft success rate and early implant survival rate after preprosthetic alveolar ridge reconstruction with autologous bone grafts. A consecutive retrospective study was conducted on all patients who were treated at the military outpatient clinic of the Department of Oral and Plastic Maxillofacial Surgery at the military hospital in Ulm (Germany) in the ...

Fig. 7. a–c Histological sections of bone core b...

Fig. 7. ing a trephine bur. a Overview image of coronal-apical cut through the entire core biopsy showing formation of new bone (NB) next to old bone of the extraction socket (B). easy-graft CRYSTAL particles (Gr) are embedded in well perfused connective tissue (CT) and new bone (NB) (Azur II and Pararosanilin, original magnification ×50). b Integration of easy-graft CRYSTAL particle (Gr) into ...

Fig. 6. a–c Four-month postoperative CBCT showin...

Fig. 6. ntegration and preservation of ridge without collapse of the buccal or lingual cortical plates also showing the cross sections in the grafted area Fig. 6. a–c Four-month postoperative CBCT showing graft integration and preservation of ridge without collapse of the buccal or lingual cortical plates also showing the cross sections in the grafted area

Fig. 5. CBCT images of the extraction site. a Preo...

Fig. 5. CBCT images of the extraction site. a Preoperative CBCT showing fractured and un-restorable teeth #45 and #46 planned to be extracted. b–d Cross sectional views Fig. 5. CBCT images of the extraction site. a Preoperative CBCT showing fractured and un-restorable teeth #45 and #46 planned to be extracted. b–d Cross sectional views

Fig. 4. a Second stage surgery followed by impress...

Fig. 4. excellent width of keratinized tissue which was also preserved. b Implant crowns placed and loaded after 3 months of placement Fig. 4. a Second stage surgery followed by impression making. Note the excellent width of keratinized tissue which was also preserved. b Implant crowns placed and loaded after 3 months of placement

Fig. 3. Postoperative X ray showing the implant po...

Fig. 3. Postoperative X ray showing the implant positions in the mandible where the teeth were extracted and ridge preservation was accomplished Fig. 3. Postoperative X ray showing the implant positions in the mandible where the teeth were extracted and ridge preservation was accomplished

Fig. 2. a Clinical postoperative view after 4 mon...

Fig. 2. ssue approximation. A good width of keratinized tissue is visible along with ridge preservation. Ready for implant placement in the grafted areas. b Implant placed in 45 area. Core biopsy sample taken from area 46. Note the integration of graft particles in the preserved alveolar ridge also inside the osteotomy site of 46. c Two Xive (Dentsply) implants placed in the preserved ridge. d. ...

Fig. 1. a Clinical occlusal view with fractured 45...

Fig. 1. ft tissue and no flap reflection on the surgical site. c Graft material condensed into the extraction sockets showing good initial graft stability. d Black silk sutures placed with tissue approximation and no releasing incision in the flaps Fig. 1. a Clinical occlusal view with fractured 45 and 46. b Post-extraction view of the socket. Note minimal trauma to the soft tissue and no fla...

Table 3 Histomorphometric evaluation of core biops...

Patient no. Gender Patient’s age Tooth no. Time post extraction [month] % New bone ...

Table 2 Width ridge changes assess by cone beam co...

Patient no. Tooth no. Ridge width baseline [mm] Ridge width implant placement [mm] Ridge width changes [mm] ...

Table 1 Buccal and palatal ISQ values at implant p...

   ISQ level at implant placement ISQ level at loading Patient no. Tooth no. Buccal Palatal ...

About this article : Ridge preservation using an i...

Kakar, A., Rao, B.H.S., Hegde, S. et al. Ridge preservation using an in situ hardening biphasic calcium phosphate (β-TCP/HA) bone graft substitute—a clinical, radiological, and histological study. Int J Implant Dent 3, 25 (2017). https://doi.org/10.1186/s40729-017-0086-2 Download citation Received: 31 December 2016 Accepted: 25 May 2017 Published: 22 June 2017 DOI: htt...

Rights and permissions : Ridge preservation using ...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Ridge preservation using an i...

Correspondence to Ashish Kakar.

Author information : Ridge preservation using an i...

Yenepoya University Dental College, University Road, Mangalore, 575018, India Ashish Kakar, Bappanadu H. Sripathi Rao & Shashikanth Hegde Dental Foundations and Research Centre, Malad, Mumbai, 400064, India Nikhil Deshpande Department of Oral and Maxillofacial Surgery, Center for Dental Medicine, Medical Center—University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany Annette ...

Acknowledgements : Ridge preservation using an in ...

We acknowledge Sunstar Suisse SA, Etoy, Switzerland, for partly supporting this clinical study with a study grant. The authors declare that there is no conflict of interest regarding the publication of this paper. Ashish Kakar, Bappanadu H. Sripathi Rao, Shashikanth Hegde, Nikhil Deshpande, Annette Lindner, Heiner Nagursky, Aditya Patney, and Harsh Mahajan declare that they have no competing inte...

References : Ridge preservation using an in situ h...

Download references

References : Ridge preservation using an in situ h...

Lang NP, Pun L, Lau KY, Li KY, Wong MC. A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012;23 Suppl 5:39–66. Smukler H, Landi L, Setayesh R. Hostomorphometric evaluation of extraction sockets and deficient alveolar ridges treated with allografts and barrier membrane. A pilot study. In...

References : Ridge preservation using an in situ h...

Nair PNR, Luder H-U, Maspero FA, Fischer JH, Schug J. Biocompatibility of beta-tricalcium phosphateroot replicas in porcine tooth extraction sockets—a correlativehistological, ultrastructural, and x-ray microanalytical pilotstudy. J Biomater Appl. 2006;20(4):307–24. Jensen SS, Terheyden H. Bone augmentation procedures in localized defects in the alveolar ridge: clinical results with different...

References : Ridge preservation using an in situ h...

Araujo MG, Sukekava F, Wennstrom J, Lindhe J. Ridge alterations following implant placement in fresh extraction sockets: an experimental study in the dog. J Clin Periodontol. 2005;32:645–52. Van der Weijden F, Dell'Acqua F, Slot DE DE. Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. J Clin Periodontol. 2009;36(12):1048–58. Schropp L, Wenzel A, Kos...

Conclusions : Ridge preservation using an in situ ...

The results of this clinical study support the use of a biphasic in situ hardening alloplastic bone graft substitute for ridge preservation in intact post-extraction sites without the use of a dental membrane. Therefore, grafting of sockets without primary wound closure or using dental membranes or a soft tissue punch can be an effective minimally invasive method of preserving the contour and arch...

Discussion : Ridge preservation using an in situ h...

Likewise, the reported amount of residual grafting material in the defect site was similar. In average, only 26.2 ± 9.4% of the defect was occupied with residual graft material in this study which is well in line with 26.6 ± 5.2% reported for BCP but below the 37.7 ± 8.5% reported for xenograft [14]. All 15 implants could be placed without the need for additional bone augmentation....

Discussion : Ridge preservation using an in situ h...

As previously reported, secondary intention soft tissue healing of grafted post-extraction sites can be well achieved when using an in situ hardening and in situ stabilizing bone graft substitutes without the need of a dental membrane [18, 20]. Findings of the present report corroborate these results. The authors found that all sites healed uneventfully with coverage of soft tissue and no local co...

Discussion : Ridge preservation using an in situ h...

Ridge preservation following dental extractions is fundamental, preserving the ridge profile for subsequent implant placement and providing a sustained function and esthetics. This clinical trial reports on the successful application of an in situ hardening biphasic alloplastic bone graft substitute for ridge preservation and subsequent implant placement in 15 healthy patients. A routine but minim...

Results : Ridge preservation using an in situ hard...

Cone beam computer tomography (CBCT) was performed before tooth extraction and at the time point of implant placement. Mean ridge width reduction before tooth extraction to implant placement was calculated to effect in 0.79 ± 0.73 mm horizontal bone loss (Table 2). Primary implant stability was achieved in all 15 cases, showed in average high ISQ levels 70.3 ± 9.7 (buccal/palatal), and...

Results : Ridge preservation using an in situ hard...

Fifteen patients (4 females and 11 males) with a mean age of 51.3 + 14.8 years (range: 27 to 75 years) participated in this randomized clinical trial. The site specific areas and teeth numbers for the study are shown in Table 1. In all cases, the postoperative healing was uneventful. Clinically, the soft tissue healing pattern observed was very similar in all cases. The soft tissue on all ...

Methods : Ridge preservation using an in situ hard...

Bone biopsies were harvested using a trephine bur at the site of implant placement. The trephine burs including the bone biopsies were fixed in 4% formalin for 5–7 days, rinsed in water, and dehydrated in serial steps of ethanol (70, 80, 90, and 100%), remaining for 1 day in each concentration. Specimens were then infiltrated, embedded, and polymerized in resin (Technovit 9100, Heraeus Kulzer,...

Methods : Ridge preservation using an in situ hard...

Antibiotic therapy consisting of 1 g amoxicillin every 12 h for 4 days and mouth rinsing with 0.2% chlorhexidine every 8 h for 10 days were prescribed. The suture was removed 1 week postoperatively. After 3 to 8 months (average 5.2 ± 2 months), the sites (Fig. 2a) were reentered for implant placement. A site-specific full thickness mucoperiosteal flap was elevated to expose the regen...

Methods : Ridge preservation using an in situ hard...

This study was approved by the Yenepoya University Ethics committee, Mangalore, India (Approval Number YOEC83/8/3/2014). Fifteen patients who required extraction of a maxillary or mandibular tooth and subsequent single-tooth implant placement and who met the inclusion and exclusion criteria were included in this prospective single-arm clinical study. The patients (4 females and 11 males) had a mea...

Background : Ridge preservation using an in situ h...

To our knowledge, this is the first systematic clinical, radiographic, and histological evaluation that assesses bone formation and ridge width preservation after socket grafting using an in situ hardening biphasic bone graft substitute in healthy patients.

Background : Ridge preservation using an in situ h...

Following tooth extraction, the alveolar ridge will decrease in volume and change its morphology [1, 2]. These changes are clinically significant [3] and can complicate the placement of a conventional bridge or an implant-supported crown. Post-extraction maintenance of the alveolar ridge following the principles of ridge preservation using bone graft substitutes minimizes ridge resorption and, thu...

Abstract : Ridge preservation using an in situ har...

Post-Extraction ridge preservation using bone graft substitutes is a conservative technique to maintain the width of the alveolar ridge. The objective of the present study was to evaluate an in situ hardening biphasic (HA/β-TCP) bone graft substitutes for ridge preservation without primary wound closure or a dental membrane. A total of 15 patients reported for tooth extraction were enrolled in t...

About this article : Sandwich bone graft for verti...

Tanaka, K., Sailer, I., Kataoka, Y. et al. Sandwich bone graft for vertical augmentation of the posterior maxillary region: a case report with 9-year follow-up. Int J Implant Dent 3, 20 (2017). https://doi.org/10.1186/s40729-017-0063-9 Download citation Received: 15 October 2016 Accepted: 13 January 2017 Published: 19 May 2017 DOI: https://doi.org/10.1186/s40729-017-0063-...

Rights and permissions : Sandwich bone graft for v...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Sandwich bone graft for verti...

Division of Oral and Maxillofacial Surgery, Department of Oral Medicine and Surgery, Tohoku University Graduate School of Dentistry, 4-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Miyagi, Japan Kenko Tanaka, Yoshihiro Kataoka, Shinnosuke Nogami & Tetsu Takahashi Division of Fixed Prosthodontics and Biomaterials Clinic of Dental Medicine, University of Geneva, 19 rue Barthélemy-Menn, CH-1205, ...

Acknowledgements : Sandwich bone graft for vertica...

The authors thank Atumu Kouketu for his figure illustration support and Kouhei Shinmyouzu for the clinical support. Authors Kenko Tanaka, Irena Sailer, Yoshihiro Kataoka, Shinnosuke Nogami, and Tetsu Takahashi declare that they have no competing interests.

References : Sandwich bone graft for vertical augm...

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References : Sandwich bone graft for vertical augm...

Thoma DS, Zeltner M, Hüsler J, Hämmerle CH, Jung RE, EAO Supplement Working Group 4 - EAO CC. Short implants versus sinus lifting with longer implants to restore the posterior maxilla: a systematic review. Clin Oral Implants Res. 2015;26:154–169. Lee SA, Lee CT, Fu MM, Elmisalati W, Chuang SK. Systematic review and meta-analysis of randomized controlled trials for the management of limited ve...

References : Sandwich bone graft for vertical augm...

Adell R, Brånemark PI. A 15-year study of osseointegrated implant in the treatment of the edentulous jaw. Int J Oral Maxillofac Surg. 1981;10:387–416. Albrektsson T, Zarb G, Worthington P, Eriksson AR. The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants. 1986;1:11–25. Cordo L, Terheyden H. ITI treatment guide vo...

Conclusions : Sandwich bone graft for vertical aug...

We described in the present case a vertical lack of the bone from the alveolar ridge to the opposing teeth, the short distance from the reabsorbed ridge to the floor of the maxillary sinus, and the presence of septa and a thickened sinus membrane within the maxillary sinus. A sandwich bone graft was successfully applied and followed up in the long term. The resulting gains in ridge height and incr...

Discussion : Sandwich bone graft for vertical augm...

In this case, the alveolar ridge was Seibert class II, and septa and a thickened sinus membrane were evident within the maxillary sinus. Sinus floor elevation was limited because of the condition of the floor morphology, the presence of septa, and the thickness of sinus floor membrane [22, 23]. Considering these issues, we selected the interpositional bone graft technique using autologous bone in ...

Discussion : Sandwich bone graft for vertical augm...

This paper reports on a segmental osteotomy procedure with an interpositional graft in the posterior maxillary region with 9 years of follow-up. The techniques used to overcome a lack of alveolar bone height rely on the placement supplemented by various vertical guided bone regeneration (GBR) procedures [4, 5] and the use of alveolar distraction osteogenesis [6], titanium mesh [7], or onlay bone...

Case presentation : Sandwich bone graft for vertic...

Six months after surgery, radiological examinations were carried out and the patient underwent implant placement (Fig. 4). The postoperative bone height had increased to 10.1 mm at position 26 and 12.9 mm at position 27 compared with the preoperative heights of 6.1 and 7.5 mm, respectively. Postoperative clearance was reduced by 11 mm compared with the preoperative clearance. Careful separati...

Case presentation : Sandwich bone graft for vertic...

A 67-year-old male patient sought implant rehabilitation for the purposes of restoration of occlusal support and assistance with chewing difficulties. Clinical and radiological examinations revealed that teeth were absent 26–27. The clearance from the alveolar ridge to the opposing teeth was 20 mm (Fig. 1). A CT scan showed that the distance from the reabsorbed ridge to the floor of the maxill...

Background : Sandwich bone graft for vertical augm...

In the literature, the technique of segmental osteotomy accompanied by interpositional grafting has been reported as a practical and predictable procedure with a low incidence of complications and a high probability of success [15,16,17,18,19]. This approach leaves the soft tissue on the oral side of the midcrestal incision attached to the crestal bone segment. Various studies have shown that alve...

Background : Sandwich bone graft for vertical augm...

Osseointegrated implants for the replacement of missing teeth have recently become a routine treatment option [1, 2]. However, any tooth loss may be followed by extensive resorption of the alveolar ridge, which usually makes implant placement difficult or impossible because of the lack of bone volume. There are a variety of defect situations with increasing complexity, ranging from fenestrations, ...

Abstract : Sandwich bone graft for vertical augmen...

The loss of teeth followed by bone resorption often lead to defects in the alveolar ridge, making installation of dental implants difficult. Correction of such bone defects, especially lack of height of the ridge, is a difficult problem for all dental surgeons. This report describes the outcome of treatment after alveolar ridge augmentation in the atrophic posterior maxillary region via segmental ...

Fig. 5. Survival rate of dental implants after aut...

Fig. 5. Survival rate of dental implants after autologous bone augmentation Fig. 5. Survival rate of dental implants after autologous bone augmentation

Fig. 4. Postoperative nerve alterations. Single as...

Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Double asterisk, N refers to the total number of the surgical approaches in the maxilla (N = 225) Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Dou...

Fig. 3. Surgical outcome after autologous augmenta...

Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites

Fig. 2. Survival rate of autologous bone grafts : ...

Fig. 2. Survival rate of autologous bone grafts Fig. 2. Survival rate of autologous bone grafts

Fig. 1. Postoperative complications at the donor a...

Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378) Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378)

Table 3 Intra- and postoperative complications aft...

Postoperative complications %/procedures (N) At donor sitea    Wound infection 2.6% (8/300) At recipient site...

Table 2 Donor sites and numbers of bone grafts as ...

Donor site Bone grafts (N)/patients (N) Lateral zygomatic buttress 113/112 Mandibular ramus (retromolar) ...

Table 1 Patient characteristics at the time of aug...

Patient characteristics N (%) Gendera    Male 250 (89.6%)  Female 29 (10.4%) ...

About this article : Autogenous bone grafts in ora...

Sakkas, A., Wilde, F., Heufelder, M. et al. Autogenous bone grafts in oral implantology—is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J Implant Dent 3, 23 (2017). https://doi.org/10.1186/s40729-017-0084-4 Download citation Received: 27 February 2017 Accepted: 22 May 2017 Published: 01 June 2017 DOI: https://doi...

Rights and permissions : Autogenous bone grafts in...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Autogenous bone grafts in ora...

Department of Oral and Plastic Maxillofacial Surgery, Military Hospital Ulm, Academic Hospital of the University of Ulm, Oberer Eselsberg 40, 89081, Ulm, Germany Andreas Sakkas, Frank Wilde, Marcus Heufelder & Alexander Schramm Institute of Anatomy, Medical Faculty of Leipzig University, Leipzig, Germany Karsten Winter Department of Oral and Plastic Maxillofacial Surgery, University Hospit...

Acknowledgements : Autogenous bone grafts in oral ...

The authors thank the patients for their kindness to participate as study cases and the whole medical team at the Bundeswehrkrankenhaus Ulm. AS participated in its design and coordination, carried out the data selection, and drafted the manuscript, and is the corresponding author. FW participated in its design and coordination and helped in drafting the manuscript. MH participated in its design a...

References : Autogenous bone grafts in oral implan...

Semper W, Kraft S, Mehrhof J, Nelson K. Impact of abutment rotation and angulation on marginal fit: theoretical considerations. Int J Oral Maxillofac Implants. 2010;25:752–8. Wiltfang J, Jätschmann N, Hedderich J, Neukam FW, Schlegel KA, Gierloff M. Effect of deproteinized bovine bone matrix coverage on the resorption of iliac cortico-spongeous bone grafts—a prospective study of two cohorts....

References : Autogenous bone grafts in oral implan...

Chiapasco M, Zaniboni M. Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations: a systematic review. Clin Oral Implants Res. 2009;20:113–23. Felice P, Pellegrino G, Checchi L, Pistilli R, Esposito M. Vertical augmentation with interpositional blocks of anorganic bovine bone vs. 7-mm-long implants in posterior mandibles: 1-year results of a randomized clinical...

References : Autogenous bone grafts in oral implan...

Verdugo F, Castillo A, Moragues MD, Pontón J. Bone microbial contamination influences autogenous grafting in sinus augmentation. J Periodontol. 2009;80:1355–64. Wiltfang J, Schultze-Mosgau S, Merten HA, Kessler P, Ludwig A, Engelke W. Endoscopic and ultrasonographic evaluation of the maxillary sinus after combined sinus floor augmentation and implant insertion. Oral Surg Oral Med Oral Pathol O...

References : Autogenous bone grafts in oral implan...

von Arx T, Buser D. Horizontal ridge augmentation using autogenous block grafts and the guided bone regeneration technique with collagen membranes: a clinical study with 42 patients. Clin Oral Implants Res. 2006;17:359–66. Levin L, Nitzan D, Schwartz-Arad D. Success of dental implants placed in intraoral block bone grafts. J Periodontol. 2007;78:18–21. Andersson L. Patient self-evaluation of...

References : Autogenous bone grafts in oral implan...

Aghaloo TL, Moy PK. Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement? Int J Oral Maxillofac Implants. 2007;22:49–70. Margonar R, dos Santos PL, Queiroz TP, Marcantonio E. Rehabilitation of atrophic maxilla using the combination of autogenous and allogeneic bone grafts followed by protocol-type prosthesis. J Craniofac Surg. 2010;2...

References : Autogenous bone grafts in oral implan...

Schwartz-Arad D, Dori S. Intraoral autogenous onlay block bone grafting for implant dentistry. Refuat Hapeh Vehashinayim. 2002;19:35–9. 77. Misch CM. Ridge augmentation using mandibular ramus bone grafts for the placement of dental implants: presentation of a technique. Pract Periodontics Aesthet Dent. 1996;8:127–35. Altiparmak N, Soydan SS, Uckan S. The effect of conventional surgery and pi...

References : Autogenous bone grafts in oral implan...

Jensen AT, Jensen SS, Worsaae N. Complications related to bone augmentation procedures of localized defects in the alveolar ridge. A retrospective clinical study. Oral Maxillofac Surg. 2016;20(2):115–22 [Epub ahead of print]. Buser D, Dula K, Hirt HP, Schenk RK. Lateral ridge augmentation using autografts and barrier membranes: clinical study with 40 partially edentulous patients. J Oral Maxill...

Conclusions : Autogenous bone grafts in oral impla...

The results of the clinical study proves the reliability and low comorbidity of autologous bone grafts in preprosthetic alveolar ridge reconstructions prior to implant insertion. The high graft success rate (95.6%) and the low early implant failure rate (0.38%) in a surveillance of all patients treated in three following years with this technique showing no exclusion and no dropout of any case for...

Discussion : Autogenous bone grafts in oral implan...

Data on risk factors based on the original examination and documentation are difficult to assess the adverse effects of variable factors on the surgical prognosis because of the multifactorial genesis of surgical complications [73]. Factors such as gender, age, or smoking habit could be associated with postoperative complications after two-stage dentoalveolar reconstruction with autologous bone gr...

Discussion : Autogenous bone grafts in oral implan...

The results of the present study have to take into account the absence of a control group with patients undergoing bone augmentation procedures with bone substitutes (allogen, alloplastic, exogen). Without a comparative group of grafting surgeries using alternative bone material, only limited statements can be made. However, the excellent surgical outcome of autologous surgical methods providing ...

Discussion : Autogenous bone grafts in oral implan...

The use of autologous bone in this study has shown excellent graft survival and success rate (95.6%). This is equal to the results from the studies on implants inserted in reconstructed sites [6, 8, 24]. The early implant survival rate of 99.7% found in the present material is very high comparable to that in the previous systematic reviews after staged horizontal ridge augmentation [9, 10, 22, 62,...

Discussion : Autogenous bone grafts in oral implan...

Of the sinus floor elevations performed in this study, 84.8% were defined absolutely successful. Only two of our 72 patients having sinus lift operations could not finally be treated with dental implants. These results are comparable to other studies considering the sinus graft to be a safe treatment modality with few complications [6, 8, 51,52,53]. Raghoebar et al. reported incidences of sinus co...

Discussion : Autogenous bone grafts in oral implan...

Postoperative morbidity after mandibular bone harvesting procedures was reported to be mainly related to temporary or permanent neural disturbances involving the inferior alveolar nerve and its branches [19]. In this study, only the incidence of the temporary hypoesthesia of the mandibular and lingual nerve after harvesting from the retromolar area could be detected. It was 10.4 and 2.8%, respecti...

Discussion : Autogenous bone grafts in oral implan...

Systematic reviews have failed to find evidence that one particular grafting technique is superior to others [10]. Intraoral bone grafts from the mandibular symphysis, mandibular ramus, and maxillary tuberosity provide a good treatment modality for ridge augmentation, and the amount of bone available for harvesting is sufficient for defects up to the width of three teeth [42]. Harvesting of retrom...

Discussion : Autogenous bone grafts in oral implan...

Several grafting procedures have been described to create sufficient volume of bone for implant placement [8, 9]. Autologous bone grafts can be harvested by an intraoral approach (mandibular ramus, mandibular symphysis, zygomatic buttress) or from distant sites (iliac crest, calvaria, and etc.) [17, 36, 37]. However, bone harvesting potentially causes donor site morbidity which is a major issue fo...

Results : Autogenous bone grafts in oral implantol...

The surgical outcome after augmentation and implantation procedures is presented in Fig. 5.

Results : Autogenous bone grafts in oral implantol...

The average healing period until implant placement after bone harvesting was 4.53 months. Initially, 546 implants in 279 patients were planned. After the healing period, it was possible to place 525 implants in 436 successfully augmented areas in 259 patients. Three hundred implants were inserted in the maxilla and 225 in the mandible. The remaining 21 implants planned for 20 patients could not b...

Results : Autogenous bone grafts in oral implantol...

Regarding intraoperative complications, all sinus membrane perforations were covered with a resorbable collagen membrane (Bio-Gide®, Geistlich Biomaterials, Baden-Baden, Germany) which applied as sealant to overlap the site of perforation prior to insertion of the graft material. These patients were advised to avoid physical stress, blowing their noses, or sneezing for a period of 3 weeks, and n...

Results : Autogenous bone grafts in oral implantol...

No permanent damage to any trigeminal nerves was evident in any of our entire cohort. All cases of postoperative hypoesthesia of the mental, lingual, or infraorbital nerve were just a temporary nature. At the time of implant surgery, none of these patients reported any persisting neural disturbances (Fig. 4). In eleven patients, hypoesthesia of the mental area was mentioned, and three of them al...

Results : Autogenous bone grafts in oral implantol...

Thirty-eight patients underwent a total of 116 augmentation procedures harvesting from the iliac crest. In 20 patients, a bone graft augmentation of the maxilla and the mandible in combination with bilateral sinus floor augmentations was performed. Eighteen patients had augmentations only in the maxilla, involving bone grafting and sinus lift elevations. Totally, 76 sinus lifts with bone material ...

Results : Autogenous bone grafts in oral implantol...

A total of 104 retromolar bone graft procedures in 86 patients were conducted. Twenty-two harvesting procedures were performed for augmentation of the maxilla and 82 for the mandible. Seven retromolar bone grafts (93.2%) in seven single-tooth gap dental regions by seven patients had been lost. Therefore, seven implants could not be inserted in augmented alveolar sites after graft failure. Three of...

Results : Autogenous bone grafts in oral implantol...

In six patients, a partial graft resorption was detected at the time of implantation and an additional simultaneous augmentation with bone chips harvested with the Safescraper device (C.G.M. S.p.A., Divisione Medicale META, Italy) was then necessary in order to ensure the osseointegration of the implants. Two out of these six cases had grafts from the crista zygomatico-alveolaris, two from the ram...

Results : Autogenous bone grafts in oral implantol...

A total of 112 sinus floor elevations were performed. In all of the cases, implants were inserted in a two-stage procedure. The donor site for harvesting the bone for the sinus elevations was in 76 procedures in the iliac crest area, and in 36 procedures, the bone was harvested with a bone scraper device from the lateral sinus wall at the site of sinus lifting. The distribution and number of tran...

Results : Autogenous bone grafts in oral implantol...

Two hundred seventy-nine patients—250 men and 29 women—underwent 456 augmentation procedures involving autologous bone grafts prior to implant placement. The patients ranged in age from 18.5 to 71.5 years (average 43.1 years) at the moment of augmentation surgery. Of those patients, 162 (58.1%) were younger than 40 years of age and 117 (41.9%) were older than 40 years of age. Caries or pe...

Methods : Autogenous bone grafts in oral implantol...

Early and late implant loss was documented in this study, defining the clinical success of osseointegration. Early implant failures were assessed before the acquisition of osseointegration, i.e., before the placement of prosthodontic restorations. Early implant failure could occur from the time of placement, during the healing phase and before abutment connection. The implant inserted after re-aug...

Methods : Autogenous bone grafts in oral implantol...

Medical history of patient Age of patient at the time of bone harvesting and augmentation History of periodontal disease Smoking habits Donor site Jaw area and dental situation of the recipient site Intraoperative complications Postoperative complications after augmentation Management of complications Bone graft stability and clinical resorption prior to implant placement Complications a...

Methods : Autogenous bone grafts in oral implantol...

In addition to the bone already gained with the bone scraper device from the sinus wall during the antrostomy, bone was harvested with the same device from the maxillary buccal buttress, if more volume was needed. By taking this approach, the collection of enough bone for the augmentation of at least two implantation sites was feasible with a mean surgical time of 5 to 10 min for harvesting. In c...

Methods : Autogenous bone grafts in oral implantol...

Grafting from the iliac crest was always performed under general anesthesia in a two-team approach. The iliac crest was exposed and autogenous grafts from the anterosuperior inner edge of the iliac wing were harvested with an oscillating saw and/or a chisel, keeping a safe distance of around 2 cm from the anterosuperior iliac spine. After harvesting the bone grafts, the corticocancellous bone blo...

Methods : Autogenous bone grafts in oral implantol...

A standardized two-stage surgical protocol was used, and all sites were treated in a similar fashion. In the first intervention, a bone block harvested from the donor site was fixed with osteosynthesis titanium screws to the recipient site as an onlay graft to achieve a horizontal and/or vertical enlargement of the alveolar ridge. Placement of the bone graft was always guided by an augmentation te...

Methods : Autogenous bone grafts in oral implantol...

For this retrospective cohort study, we reviewed the records of all patients without exclusion criteria who were referred to the department of oral and plastic maxillofacial surgery at the military hospital of Ulm, Germany, between January 2009 and December 2011 for alveolar ridge augmentations prior to implant insertions using autologous bone grafts harvested from different donor sites and unilat...

Background : Autogenous bone grafts in oral implan...

In our military outpatient center exclusively, autologous bone transplantations harvested from different donor sites were used intraorally (crista zygomatico-alveolaris, ramus mandible, symphysis mandible, anterior sinus wall) and extraorally (iliac crest) to reconstruct severe horizontal and/or vertical alveolar ridge atrophy prior to implant placement. The aim of this study was to assess the cli...

Background : Autogenous bone grafts in oral implan...

Although the iliac crest is most often used in jaw reconstruction, a significant bone resorption has been mentioned [12]. This disadvantage, and the fact that dental implants do not always require a large amount of bone, has increased the use of autologous block bone grafts from intraoral sources [13]. Bone grafts from intraoral donor sites offer several benefits like surgical accessibility, proxi...

Background : Autogenous bone grafts in oral implan...

Oral implantation has a significant role in the rehabilitation of patients. Bone reconstruction techniques have been advanced in order to optimize the esthetic and functional outcome. However, the restoration of the oral function of atrophic alveolar crests still remains a challenge in oral implantology. Bone augmentation procedures are often indicated to allow implant placement in an optimal thre...

Abstract : Autogenous bone grafts in oral implanto...

This review demonstrates the predictability of autologous bone material in alveolar ridge reconstructions prior to implant insertion, independent from donor and recipient site including even autologous bone chips for sinus elevation. Due to the low harvesting morbidity of autologous bone grafts, the clinical results of our study indicate that autologous bone grafts still remain the “gold standar...

Abstract : Autogenous bone grafts in oral implanto...

This study assessed the clinical outcomes of graft success rate and early implant survival rate after preprosthetic alveolar ridge reconstruction with autologous bone grafts. A consecutive retrospective study was conducted on all patients who were treated at the military outpatient clinic of the Department of Oral and Plastic Maxillofacial Surgery at the military hospital in Ulm (Germany) in the ...

Fig. 7. a–c Histological sections of bone core b...

Fig. 7. image of coronal-apical cut through the entire core biopsy showing formation of new bone (NB) next to old bone of the extraction socket (B). easy-graft CRYSTAL particles (Gr) are embedded in well perfused connective tissue (CT) and new bone (NB) (Azur II and Pararosanilin, original magnification ×50). b Integration of easy-graft CRYSTAL particle (Gr) into newly formed bone (NB) and conn...

Fig. 6. a–c Four-month postoperative CBCT showin...

Fig. 6. graft integration and preservation of ridge without collapse of the buccal or lingual cortical plates also showing the cross sections in the grafted area Fig. 6. a–c Four-month postoperative CBCT showing graft integration and preservation of ridge without collapse of the buccal or lingual cortical plates also showing the cross sections in the grafted area

Fig. 5. CBCT images of the extraction site. a Preo...

Fig. 5. CBCT images of the extraction site. a Preoperative CBCT showing fractured and un-restorable teeth #45 and #46 planned to be extracted. b–d Cross sectional views Fig. 5. CBCT images of the extraction site. a Preoperative CBCT showing fractured and un-restorable teeth #45 and #46 planned to be extracted. b–d Cross sectional views

Fig. 4. a Second stage surgery followed by impress...

Fig. 4. lant crowns placed and loaded after 3 months of placement Fig. 4. a Second stage surgery followed by impression making. Note the excellent width of keratinized tissue which was also preserved. b Implant crowns placed and loaded after 3 months of placement

Fig. 3. Postoperative X ray showing the implant po...

Fig. 3. Postoperative X ray showing the implant positions in the mandible where the teeth were extracted and ridge preservation was accomplished Fig. 3. Postoperative X ray showing the implant positions in the mandible where the teeth were extracted and ridge preservation was accomplished

Fig. 2. a Clinical postoperative view after 4 mon...

Fig. 2. ximation. A good width of keratinized tissue is visible along with ridge preservation. Ready for implant placement in the grafted areas. b Implant placed in 45 area. Core biopsy sample taken from area 46. Note the integration of graft particles in the preserved alveolar ridge also inside the osteotomy site of 46. c Two Xive (Dentsply) implants placed in the preserved ridge. d. Postoperat...

Fig. 1. a Clinical occlusal view with fractured 45...

Fig. 1. traction sockets showing good initial graft stability. d Black silk sutures placed with tissue approximation and no releasing incision in the flaps Fig. 1. a Clinical occlusal view with fractured 45 and 46. b Post-extraction view of the socket. Note minimal trauma to the soft tissue and no flap reflection on the surgical site. c Graft material condensed into the extraction sockets sho...

Table 3 Histomorphometric evaluation of core biops...

Patient no. Gender Patient’s age Tooth no. Time post extraction [month] % New bone ...

Table 2 Width ridge changes assess by cone beam co...

Patient no. Tooth no. Ridge width baseline [mm] Ridge width implant placement [mm] Ridge width changes [mm] ...

Table 1 Buccal and palatal ISQ values at implant p...

   ISQ level at implant placement ISQ level at loading Patient no. Tooth no. Buccal Palatal ...

About this article : Ridge preservation using an i...

Kakar, A., Rao, B.H.S., Hegde, S. et al. Ridge preservation using an in situ hardening biphasic calcium phosphate (β-TCP/HA) bone graft substitute—a clinical, radiological, and histological study. Int J Implant Dent 3, 25 (2017). https://doi.org/10.1186/s40729-017-0086-2 Download citation Received: 31 December 2016 Accepted: 25 May 2017 Published: 22 June 2017 DOI: htt...

Rights and permissions : Ridge preservation using ...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Ridge preservation using an i...

Correspondence to Ashish Kakar.

Author information : Ridge preservation using an i...

Yenepoya University Dental College, University Road, Mangalore, 575018, India Ashish Kakar, Bappanadu H. Sripathi Rao & Shashikanth Hegde Dental Foundations and Research Centre, Malad, Mumbai, 400064, India Nikhil Deshpande Department of Oral and Maxillofacial Surgery, Center for Dental Medicine, Medical Center—University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany Annette ...

Acknowledgements : Ridge preservation using an in ...

We acknowledge Sunstar Suisse SA, Etoy, Switzerland, for partly supporting this clinical study with a study grant. The authors declare that there is no conflict of interest regarding the publication of this paper. Ashish Kakar, Bappanadu H. Sripathi Rao, Shashikanth Hegde, Nikhil Deshpande, Annette Lindner, Heiner Nagursky, Aditya Patney, and Harsh Mahajan declare that they have no competing inte...

References : Ridge preservation using an in situ h...

Download references

References : Ridge preservation using an in situ h...

Lang NP, Pun L, Lau KY, Li KY, Wong MC. A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012;23 Suppl 5:39–66. Smukler H, Landi L, Setayesh R. Hostomorphometric evaluation of extraction sockets and deficient alveolar ridges treated with allografts and barrier membrane. A pilot study. In...

References : Ridge preservation using an in situ h...

Nair PNR, Luder H-U, Maspero FA, Fischer JH, Schug J. Biocompatibility of beta-tricalcium phosphateroot replicas in porcine tooth extraction sockets—a correlativehistological, ultrastructural, and x-ray microanalytical pilotstudy. J Biomater Appl. 2006;20(4):307–24. Jensen SS, Terheyden H. Bone augmentation procedures in localized defects in the alveolar ridge: clinical results with different...

References : Ridge preservation using an in situ h...

Araujo MG, Sukekava F, Wennstrom J, Lindhe J. Ridge alterations following implant placement in fresh extraction sockets: an experimental study in the dog. J Clin Periodontol. 2005;32:645–52. Van der Weijden F, Dell'Acqua F, Slot DE DE. Alveolar bone dimensional changes of post-extraction sockets in humans: a systematic review. J Clin Periodontol. 2009;36(12):1048–58. Schropp L, Wenzel A, Kos...

Conclusions : Ridge preservation using an in situ ...

The results of this clinical study support the use of a biphasic in situ hardening alloplastic bone graft substitute for ridge preservation in intact post-extraction sites without the use of a dental membrane. Therefore, grafting of sockets without primary wound closure or using dental membranes or a soft tissue punch can be an effective minimally invasive method of preserving the contour and arch...

Discussion : Ridge preservation using an in situ h...

Likewise, the reported amount of residual grafting material in the defect site was similar. In average, only 26.2 ± 9.4% of the defect was occupied with residual graft material in this study which is well in line with 26.6 ± 5.2% reported for BCP but below the 37.7 ± 8.5% reported for xenograft [14]. All 15 implants could be placed without the need for additional bone augmentation....

Discussion : Ridge preservation using an in situ h...

As previously reported, secondary intention soft tissue healing of grafted post-extraction sites can be well achieved when using an in situ hardening and in situ stabilizing bone graft substitutes without the need of a dental membrane [18, 20]. Findings of the present report corroborate these results. The authors found that all sites healed uneventfully with coverage of soft tissue and no local co...

Discussion : Ridge preservation using an in situ h...

Ridge preservation following dental extractions is fundamental, preserving the ridge profile for subsequent implant placement and providing a sustained function and esthetics. This clinical trial reports on the successful application of an in situ hardening biphasic alloplastic bone graft substitute for ridge preservation and subsequent implant placement in 15 healthy patients. A routine but minim...

Results : Ridge preservation using an in situ hard...

Cone beam computer tomography (CBCT) was performed before tooth extraction and at the time point of implant placement. Mean ridge width reduction before tooth extraction to implant placement was calculated to effect in 0.79 ± 0.73 mm horizontal bone loss (Table 2). Primary implant stability was achieved in all 15 cases, showed in average high ISQ levels 70.3 ± 9.7 (buccal/palatal), and...

Results : Ridge preservation using an in situ hard...

Fifteen patients (4 females and 11 males) with a mean age of 51.3 + 14.8 years (range: 27 to 75 years) participated in this randomized clinical trial. The site specific areas and teeth numbers for the study are shown in Table 1. In all cases, the postoperative healing was uneventful. Clinically, the soft tissue healing pattern observed was very similar in all cases. The soft tissue on all ...

Methods : Ridge preservation using an in situ hard...

Bone biopsies were harvested using a trephine bur at the site of implant placement. The trephine burs including the bone biopsies were fixed in 4% formalin for 5–7 days, rinsed in water, and dehydrated in serial steps of ethanol (70, 80, 90, and 100%), remaining for 1 day in each concentration. Specimens were then infiltrated, embedded, and polymerized in resin (Technovit 9100, Heraeus Kulzer,...

Methods : Ridge preservation using an in situ hard...

Antibiotic therapy consisting of 1 g amoxicillin every 12 h for 4 days and mouth rinsing with 0.2% chlorhexidine every 8 h for 10 days were prescribed. The suture was removed 1 week postoperatively. After 3 to 8 months (average 5.2 ± 2 months), the sites (Fig. 2a) were reentered for implant placement. A site-specific full thickness mucoperiosteal flap was elevated to expose the regen...

Methods : Ridge preservation using an in situ hard...

This study was approved by the Yenepoya University Ethics committee, Mangalore, India (Approval Number YOEC83/8/3/2014). Fifteen patients who required extraction of a maxillary or mandibular tooth and subsequent single-tooth implant placement and who met the inclusion and exclusion criteria were included in this prospective single-arm clinical study. The patients (4 females and 11 males) had a mea...

Background : Ridge preservation using an in situ h...

To our knowledge, this is the first systematic clinical, radiographic, and histological evaluation that assesses bone formation and ridge width preservation after socket grafting using an in situ hardening biphasic bone graft substitute in healthy patients.

Background : Ridge preservation using an in situ h...

Following tooth extraction, the alveolar ridge will decrease in volume and change its morphology [1, 2]. These changes are clinically significant [3] and can complicate the placement of a conventional bridge or an implant-supported crown. Post-extraction maintenance of the alveolar ridge following the principles of ridge preservation using bone graft substitutes minimizes ridge resorption and, thu...

Abstract : Ridge preservation using an in situ har...

Post-Extraction ridge preservation using bone graft substitutes is a conservative technique to maintain the width of the alveolar ridge. The objective of the present study was to evaluate an in situ hardening biphasic (HA/β-TCP) bone graft substitutes for ridge preservation without primary wound closure or a dental membrane. A total of 15 patients reported for tooth extraction were enrolled in t...

Fig. 1. Search strategy for BMAC : Maxillary sinus...

Fig. 1. Search strategy for BMAC Fig. 1. Search strategy for BMAC

Table 2 Characteristics of selected studies : Maxi...

Study Treatment groups No. of patients (age range) No. of maxillary sinuses evaluated Donor site for BMAC C...

Table 1 OHAT risk of bias assessment : Maxillary s...

  Study de Oliveira et al. [12] Pasquali et al. [7] Payer et al. [2] Sauerbier et al. [11] ...

About this article : Maxillary sinus augmentation ...

Ting, M., Afshar, P., Adhami, A. et al. Maxillary sinus augmentation using chairside bone marrow aspirate concentrates for implant site development: a systematic review of histomorphometric studies. Int J Implant Dent 4, 25 (2018). https://doi.org/10.1186/s40729-018-0137-3 Download citation Received: 20 February 2018 Accepted: 21 May 2018 Published: 03 September 2018 DOI:...

Rights and permissions : Maxillary sinus augmentat...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Maxillary sinus augmentation...

This is a systematic review of published data; no patients were involved in the conduct of this review. Miriam Ting, Philip Afshar, Arik Adhami, Stanton M. Braid, and Jon B. Suzuki declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Maxillary sinus augmentation ...

Correspondence to Miriam Ting.

Author information : Maxillary sinus augmentation ...

Private practice in Periodontology, and Think Dental Learning Institute, Paoli, PA, 19301, USA Miriam Ting Temple University Kornberg School of Dentistry, 3223 North Broad Street, Philadelphia, PA, 19140, USA Philip Afshar & Arik Adhami Division of Oral and Maxillofacial Surgery, Department of Oral Medicine, Pathology and Surgery, Temple University Kornberg School of Dentistry, 3223 North Br...

Availability of data and materials : Maxillary sin...

All the data generated during this systematic review were included in this manuscript.

References : Maxillary sinus augmentation using ch...

Rooney AA, Boyles AL, Wolfe MS, Bucher JR, Thayer KA. Systematic review and evidence integration for literature-based environmental health science assessments. Environ Health Perspect. 2014;122(7):711–8. Sauerbier S, Rickert D, Gutwald R, Nagursky H, Oshima T, Xavier SP, et al. Bone marrow concentrate and bovine bone mineral for sinus floor augmentation: a controlled, randomized, single-blinded...

References : Maxillary sinus augmentation using ch...

Tatum H Jr. Maxillary and sinus implant reconstructions. Dent Clin N Am. 1986;30(2):207–29. Payer M, Lohberger B, Strunk D, Reich KM, Acham S, Jakse N. Effects of directly autotransplanted tibial bone marrow aspirates on bone regeneration and osseointegration of dental implants. Clin Oral Implants Res. 2014;25(4):468–74. Chaushu G, Vered M, Mardinger O, Nissan J. Histomorphometric analysis a...

Abbreviations : Maxillary sinus augmentation using...

Bone marrow aspirate concentrate Confidence limits Ethylenediaminetetraacetic acid Technique involving bone marrow-derived mononuclear cell isolation by synthetic polysaccharide Mononuclear cells Mesenchymal stem cells Office of Health Assessment and Translation Standard deviation

Conclusions : Maxillary sinus augmentation using c...

Within the limits of this systematic review, the chairside method to harvest BMAC is a viable option for maxillary sinus augmentation for implant site development. The implant survival of the BMAC group was similar to the laboratory FICOLL concentration of BMAC group, without the additional cost and time of laboratory cell isolation techniques. Single or double centrifugation of BMAC does not appe...

Discussion : Maxillary sinus augmentation using ch...

In addition, the parameters to evaluate new bone formation were variable. New bone formation and percentage of vital bone are different methods to measure bone formation, and the data from different methods could not be combined or analyzed together. Furthermore, the BMAC evaluated in test groups were prepared differently and were harvested from different sources (tibia or iliac). The control grou...

Discussion : Maxillary sinus augmentation using ch...

Although the variations of the materials and methods for BMAC preparation were discussed, this review was not aimed to compare materials and methods for BMAC preparation, but rather the end clinical result for new bone formation and implant survival. Although implant survival and new bone formation were not the only parameters to consider when evaluating sinus augmentation, these parameters were t...

Discussion : Maxillary sinus augmentation using ch...

It appears that BMAC offers no statistically significant advantage for regeneration of bone in the maxillary sinus for site preparation of dental implants. BMAC + bovine bone graft results in similar regeneration outcome measures histologically as alveolar bone alone at 3–4 months. Measured histomorphometrically MSCs treated by FICOLL–Hypaque centrifugation to consolidate osteogenic and osteo...

Discussion : Maxillary sinus augmentation using ch...

Pasquali et al. [7], in eight patients compared BMAC + bovine bone graft (test group) with bovine bone graft alone (control group). New bone (55.15%) was reported in the test group compared with new bone (27.3%) in the control group based on histomorphometric analyses. This reported observation indicating statistically more new bone regeneration in the BMAC + bovine bone graft group compared with ...

Discussion : Maxillary sinus augmentation using ch...

Sauerbier et al. [14] further compared BMAC + bovine bone grafts (test group) with alveolar bone, autologous + bovine bone grafts (control group) for maxillary sinus site preparation. New bone (31.3%) for the test group compared with new bone (19.3%) for the control group statistically indicated equivalence in histomorphometric outcome. Histologic images showing impressive new bone formation were ...

Discussion : Maxillary sinus augmentation using ch...

Mesenchymal stem cells (MSCs) in BMAC have the potential to renew, experience clonal expansion, and differentiate into musculoskeletal tissues [16]. MSCs are also known to have an immunoregulatory role and may enhance the normal healing response and angiogenesis [10]. BMAC has been used in bone, cartilage, and tendon injuries with encouraging results [16]. BMAC is a minimally invasive procedure, a...

Results : Maxillary sinus augmentation using chair...

The search generated 797 reviews in PubMed, 114 in Web of Science, 97 in Cochrane Library, and 319 in Google Scholar (Fig. 1). The following were selected after the title and abstract screening: 18 were selected from PubMed, 23 from Web of Science, 6 from Cochrane Library, 2 from Google Scholar, and 2 from hand searching the reference list of the selected article. After the duplicates were remove...

Materials and methods : Maxillary sinus augmentati...

What are the histomorphometric outcomes of sinus augmentation with bone marrow aspirate concentrates obtained chairside? PubMed, Web of Science, Cochrane Library, and Google Scholar were searched up to January 2017. Google scholar was searched for gray literature. The following keywords were used: “bone marrow aspirate concentrates,” “stem cells,” “histomorphometric,” and “bone graf...

Review : Maxillary sinus augmentation using chairs...

Maxillary sinus augmentation is indicated when there is an inadequate vertical alveolar bone height to effectively support surgically placed dental implants. The sinus elevation procedure requires grafting bone material onto the sinus floor to regenerate sufficient vertical alveolar bone height [1, 2]. The ideal bone grafting material should be biocompatible, possess no risk of disease transmissio...

Abstract : Maxillary sinus augmentation using chai...

Maxillary sinus pneumatization following dental tooth extractions and maxillary alveolar bone resorption frequently leaves inadequate bone levels for implant placement. The objectives of this systematic review are to evaluate the effects of bone marrow aspirate concentrates (BMACs) used in maxillary sinus augmentation for implant site development. A systematic search was conducted using PubMed, E...

Fig. 4. Statistical analysis for different variabl...

Fig. 4. Statistical analysis for different variables. a Weighted mean survival rate. b Implant survival rate according to degree of penetration. c Analysis of clinical complications. d Analysis of radiographic complications Fig. 4. Statistical analysis for different variables. a Weighted mean survival rate. b Implant survival rate according to degree of penetration. c Analysis of clinical com...

Fig. 3. Graphic representation of group 1 ≤ 4...

Fig. 3. Graphic representation of group 1 ≤ 4 mm penetration and group 2 > 4 mm penetrations Fig. 3. Graphic representation of group 1 ≤ 4 mm penetration and group 2 > 4 mm penetrations

Fig. 1. Graphic representation of implants intrudi...

Fig. 1. Graphic representation of implants intruding sinus perforating or not the Schneiderian membrane Fig. 1. Graphic representation of implants intruding sinus perforating or not the Schneiderian membrane

Fig. 2. PRISMA flowchart of the screening process ...

Fig. 2. PRISMA flowchart of the screening process Fig. 2. PRISMA flowchart of the screening process

Table 3 Articles excluded and reasons for exclusio...

Reason for exclusion Investigations Study design (case series or case report) Kim et al. (2017), Hatano et al. (2007) Different grafting techn...

Table 2 Characteristics of the included investigat...

Author (year) Study design Follow-up (months) N of patients N of implants Smokers Le...

Table 1 Clinical and radiographic complications re...

Clinical complications Radiographic complications Sinusitis Thickening of Schneiderian membrane Nasal bleeding, nasal obstruction, nasal secre...

About this article : Influence of exposing dental ...

Ragucci, G.M., Elnayef, B., Suárez-López del Amo, F. et al. Influence of exposing dental implants into the sinus cavity on survival and complications rate: a systematic review. Int J Implant Dent 5, 6 (2019). https://doi.org/10.1186/s40729-019-0157-7 Download citation Received: 09 October 2018 Accepted: 06 January 2019 Published: 05 February 2019 DOI: https://doi.org/10...

Rights and permissions : Influence of exposing den...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Influence of exposing dental...

Not applicable Not applicable Gian Maria Ragucci, Basel Elnayef, Fernando Suárez López del Amo, Hom-Lay Wang, Federico Hernández-Alfaro, and Jordi Gargallo-Albiol declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Influence of exposing dental ...

Correspondence to Basel Elnayef.

Author information : Influence of exposing dental ...

Department of Oral and Maxillofacial Surgery, International University of Catalonia, C/Josep Trueta Sn, Sant Cugat del Vallés, C.P 08195, Barcelona, Spain Gian Maria Ragucci, Basel Elnayef, Federico Hernández-Alfaro & Jordi Gargallo-Albiol Department of Periodontics, University of Oklahoma Health Sciences Center – College of Dentistry, Oklahoma City, OK, USA Fernando Suárez-López del ...

Acknowledgements : Influence of exposing dental im...

The authors want to thank Mr Juan Luis Gómez Martínez for the support in the statistical analysis. Not applicable Not applicable The authors do not have any financial interests, either directly or indirectly, in the products or information listed in the paper.

References : Influence of exposing dental implants...

Schwarz L, Schiebel V, Hof M, Ulm C, Watzek G, Pommer B. Risk factors of membrane perforation and postoperative complications in sinus floor elevation surgery: review of 407 augmentation procedures. J Oral Maxillofac Surg. 2015;73:1275–82. Jung JA, Choi BH, Zhu SJ, Lee SH, Huh JY, You TM, Lee HJ, Li J. The effects of exposing dental implants to the maxillary sinus cavity on sinus complications....

References : Influence of exposing dental implants...

Ardekian L, Oved-Peleg E, Mactei EE, Peled M. The clinical significance of sinus membrane perforation during augmentation of the maxillary sinus. J Oral Maxillofac Surg. 2006 Feb;64(2):277–82. Anavi Y, Allon DM, Avishai G, Calderon S. Complications of maxillary sinus augmentations in a selective series of patients. Oral Surg Oral Med Oral Patho Oral RadiolEndod. 2008;106(1):34–8. Van den Ber...

References : Influence of exposing dental implants...

Curi MM, Cardoso CL, de Ribeiro C. Retrospective study of pterygoid implants in the atrophic posterior maxilla: implant and prosthesis survival rates up to 3 years. Int J Oral Maxillofac Implants. 2015;30(2):378–83. Boyne PJ, James RA. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg. 1980;38(8):613–6. Tatum H.Jr. Maxillary and sinus implant reconstructions....

References : Influence of exposing dental implants...

Roccuzzo M, Bonino L, Dalmasso P, Aglietta M. Long-term results of a three arms prospective cohort study on implants in periodontally compromised patients: 10-year data around sandblasted and acid-etched (SLA) surface. Clin Oral Implants Res. 2014;25(10):1105–12. Esposito M, Grusovin MG, Rees J, Karasoulos D, Felice P, Alissa R, Worthington H, Coulthard P. Effectiveness of sinus lift procedures...

Conclusions : Influence of exposing dental implant...

The current review showed that the exposure of dental implants in the sinus cavity without the augmentation procedure or graft materials shows a high survival rate of 95.6%, without statistically significant differences according to the level of penetration (lower or higher to 4 mm). Changes in maxillary sinuses in relation to protruding implants within the sinus cavity do not statically affect ...

Discussion : Influence of exposing dental implants...

Consequently, it seems that maxillary sinus changes in relation to protruded implants inside the sinus cavity and does not statically affect to implant survival rate neither to clinical nor radiographic complications. Several limitations could be described for the present review. Firstly, there is a lack of a control group in the included studies, to compare outcomes and complications, with impla...

Discussion : Influence of exposing dental implants...

Pneumatization of the maxillary sinus and resorption of the residual alveolar ridge following tooth extraction can compromise the dental implant placement. Similarly, extension of the dental implants inside the maxillary sinus cavity is not rare. Some studies have observed some differences in relation to the depth of the implant extension inside the sinus cavity. When the implants penetrate inside...

Results : Influence of exposing dental implants in...

Seven studies [27,28,29,30,31,32,33] provide information on clinical complications with a global sample of 232 patients. Clinical complications among the different authors range from 0 to 14.3%, being the weighted mean complication rate 3.4% with an IC 95% [0 7.5] (Fig. 4c) Clinical complications analyzed in the studies were sinusitis, nasal bleeding, nasal obstruction, nasal secretion, mucopurul...

Results : Influence of exposing dental implants in...

An initial screening yielded a total of 3551 publications of which 26 potentially relevant articles were selected after an evaluation of their titles and abstracts. Full text of these articles was obtained and evaluated thoroughly. Of these, eight articles [26,27,28,29,30,31,32,33] (Table 2) fulfilled the inclusion criteria and subsequently were included in the qualitative analysis (Fig. 2). Rea...

Materials and methods : Influence of exposing dent...

Heterogeneity was assessed based on calculation of the I2 statistic (percentage variability of estimated effect that can be attributed to the heterogeneity of the effects) and the null statistic test. Galbraith graphs displayed the degree of heterogeneity. In studies where great heterogeneity was detected, a sensitivity analysis was performed to determine its source. Funnel plots and the Egger tes...

Materials and methods : Influence of exposing dent...

Articles were included in this systematic review if they met the following inclusion criteria: human prospective or retrospective studies, reporting outcomes of implant placed perforating the sinus floor with implant burs, and without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material. The intrusion into the sinus cavity can occur during drilling or implant p...

Materials and methods : Influence of exposing dent...

This systematic review and subsequent meta-analysis follow the guidelines of the PRISMA statement. The following focus question was developed: Is the intrusion of dental implants into the sinus cavity during implant drilling or implant placement, without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material, has an effect on implant survival or increase clinica...

Introduction : Influence of exposing dental implan...

Intrusion of dental implants into the maxillary sinus perforating through the Schneiderian membrane is considered a cause of undesirable complications [24, 25]. However, this phenomenon has never been properly evaluated and systematically studied. For this reason, the aim of this systematic review was to assess the implant survival and complication rates of implants intruding into the sinus cavity...

Introduction : Influence of exposing dental implan...

The edentulous posterior maxillary region often presents with unique challenging conditions in implant dentistry [1]. Limited bone height secondary to pneumatization of the maxillary sinus and the resorption of the alveolar ridge preclude in many instances the installation of dental implants. To compensate for the lack of bone height, several treatment options have been proposed. The most conserv...

Abstract : Influence of exposing dental implants i...

The overall survival rate of the implants into the sinus cavity was 95.6%, without statistical differences according to the level of penetration. The clinical and radiological complications were 3.4% and 14.8% respectively. The most frequent clinical complication was the epistaxis, and the radiological complication was thickening of the Schneiderian membrane, without reaching statistical significa...

Abstract : Influence of exposing dental implants i...

After tooth loss, the posterior maxilla is usually characterized by limited bone height secondary to pneumatization of the maxillary sinus and/or collapse of the alveolar ridge that preclude in many instances the installation of dental implants. In order to compensate for the lack of bone height, several treatment options have been proposed. These treatment alternatives aimed at the installation o...

Table 4 Implant survival in autogenous bone grafts...

  RDX No RDX Author Year of publication No. of implants placed into autogenous bone grafts with RDX (and failures) Overall implant survival of implants placed into autogenous bone grafts with RDX No. of patients who had implants placed into autogenous bone grafts with RDX (and failures) Patient based implant survival of implant placed into autogenous bone grafts with RDX No. of...

Table 3 Implant survival in autogenous bone grafts...

  Non-vascularised bone graft Vascularised bone graft Author Year of publication No. of patients who had implants placed into non-vascularised autogenous bone grafts (and failures) Overall patient implant survival in non-vascularised autogenous bone grafts No. of implants placed into non-vascularised autogenous bone grafts (and failures) Overall implant survival in non-vasculari...

Table 2 Summary of implant survival and implant su...

  Implant survival Implant success Author Year of publication Donor site of autogenous bone graft Radiotherapy/chemotherapy to bone graft site Complications No. of patients who had implants placed into autogenous bone grafts (and failures) Overall patient implant survival in autogenous bone grafts No. of implants placed into autogenous bone grafts (and failures) Overall i...

Table 1 Study characteristics and MINORS scores

Author Year of publication Study design Outcome measure Criteria—survival Criteria—success Quality assessment using the MINORS assessment tool Head and neck cancer diagnosis Patients age range Follow-up period Implant site Implant system Implant placement protocol Prosthodontic rehabilitation Studies with an average follow-up of 3 years or greater Watzinger et...

Figure 1. Flow chart of study selection procedure

Figure 1. Flow chart of study selection procedure

References : Survival of dental implants placed

References Schoen PJ, Reintsema H, Raghoebar GM, Vissink A, Roodenburg JLN. The use of implant retained mandibular prostheses in the oral rehabilitation of head and neck cancer patients. A review and rationale for treatment planning. Oral Oncol. 2004;40:862–71. Müller F, Schädler M, Wahlmann U, Newton JP. The use of implant-supported prostheses in the functional and psychosocial rehabi...

Conclusion : Survival of dental implants placed

Conclusion Within the limitations of the current review, it can be concluded that implant survival in autogenous bone grafts in H&N oncology patients appears to be promising with implant survival being reported at over 80% in 16 of the 20 studies included with 11 of these reporting implant survival of over 90% in follow-up ranging from 3 months [28] to 15 years [5]. However, there i...

Discussion : Survival of dental implants placed (3...

A clear deficiency of many of the studies was the imprecise and inconsistent definitions of implant survival or implant success, as detailed in Table 1. In addition, in a number of studies, the terminology ‘implant success’ and ‘implant survival’ were used interchangeably within the narrative making comparison of the studies challenging and rendering statistical analysis of the surv...

Discussion : Survival of dental implants placed (2...

The implant placement protocol with regard to primary (immediate) or secondary (delayed) implant placement was also reviewed, and there is limited evidence from Fenlon et al. that implant failure is significantly worse in immediately placed implants in comparison with a delayed approach in free vascularized grafts. Implant success was shown to be lower than implant survival and was related ...

Discussion : Survival of dental implants placed (1...

Discussion Summary of evidence Dental implants are now perceived to be a vital part of the clinician’s armamentarium in the provision of oral and dental rehabilitation for patients with acquired deformity following management of their H&N cancer, and therefore, this systematic review is relevant to clinicians and stakeholders involved in the treatment and management of H&N cancer patient...

Results : Survival of dental implants placed (8)

Six of these studies (Schultes et al., Wang et al., Zou et al., Chiapasco et al., Chiapasco et al., Wu et al.) reported some of this lack of success to the peri-implant soft tissue which was most frequently the soft tissue component of a combined bone and soft tissue free flap (most commonly the external skin). Complications A variety of implant-based complications were documented. Complicatio...

Results : Survival of dental implants placed (7)

Implant survival and Peri-implant soft tissue Only one study (Linsen et al. ) reported on the effect of the peri-implant soft tissue and implant survival of implants placed into autogenous bone grafts. Linsen et al. reported a higher implant failure of implants placed into bone and soft tissue grafts in comparison to implants placed into a bone grafts with residual soft tissues. This difference...

Results : Survival of dental implants placed (6)

However, in two studies (Teoh et al., Burgess et al.), no statistical significance was found despite higher implant failure. Primary and secondary implant placement and implant survival Six studies clearly reported the use of both primary and secondary implant placement within their study (Fenlon et al., Ch’ng et al., Zou et al., Burgess et al., Watzinger et al., Wu et al.); however, only on...

Results : Survival of dental implants placed (5)

Two studies (Fenlon et al., Burgess et al. ) reported no significant effect on implant survival in varying graft donor sites; however, three studies (Hessling et al., Shaw et al., Chiapasco et al.) reported varying implant survival rates within different autogenous bone grafts but only one study (Hessling et al.) reported that implant loss was significant with this being for implants placed into...

Results : Survival of dental implants placed (4)

Autogenous bone graft type and implant survival Seventeen studies reported on the specific bone graft type (non-vascularised or vascularised) into which the implants were placed. In the remaining three studies (Buddula et al., Fierz et al., Yerit et al.), this distinction was not possible. Of these 17 studies, 8 studies reported on implant survival in non-vascularised bone grafts and 14 studie...

Results : Survival of dental implants placed (3)

The surgical and loading implant protocols were reported in 17 studies with no description given in 3 studies (Barrowman et al., Fierz et al., Hessling et al.). The implant placement protocols were diverse with variables including the use of surgical templates/guides, primary and/or secondary implant placement following autogenous bone grafting, and immediate and/or delayed implant loading; howe...

Results : Survival of dental implants placed (2)

These 20 studies were published over a range of 21 years (1996 to 2017) and provide cumulative data on 1905 implants placed into autogenous bone grafts in H&N cancer patients with both benign and malignant tumours being reported. The exact patient number for this intervention within some of the studies was unclear as a result of the studies reporting on implant rather than patient number or ther...

Results : Survival of dental implants placed (1)

Results Study selection Searches of EMBASE, the Cochrane Central Register of Controlled Trials, Science Direct and MEDLINE generated 619 articles. After duplicate articles were removed, 566 unique articles were remaining. After the review of the titles and abstracts, 151 articles were accepted for further consideration, and 415 were rejected. After the full text was attained and reviewed for t...

Methods : Survival of dental implants placed (3)

Data items Data was collected for implant survival, implant success, implant failure, implant complications, surgical implant placement protocol, implant system used, clinical follow-up, how the author defined success/survival, the type of autogenous bone graft, implant site, the prosthodontic rehabilitation and type of cancer, and the use of radiotherapy were documented where possible. Risk of ...

Methods : Survival of dental implants placed (2)

Information sources Four electronic databases were used to systematically search the available literature: (1) The National Library of Medicine (MEDLINE via PubMed), (2) EMBASE, (3) Cochrane Central Register of Controlled Trials and (4) Science Direct. The searches were limited to studies involving human subjects and publication dates from January 1980 to August 2017 that satisfied the inclusion ...

Methods : Survival of dental implants placed (1)

Methods Protocol The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for describing and summarising the results of our review was used. A quality assessment of all selected full-text articles was performed using the Methodological Index for Non-Randomized Studies (MINORS) assessment tool to assess the risk of bias of the included studies. The MINORS scoring list co...

Introduction : Survival of dental implants placed

Introduction Rationale The use of implants to retain prostheses as part of oral and dental rehabilitation of head and neck (H&N) cancer patients is becoming an increasingly common treatment approach. A number of benefits advocating implant anchorage over conventionally secured prostheses have been proposed but importantly include a significant improvement in the reported quality of life (QoL) of...

Survival of dental implants placed in autogenous b...

Survival of dental implants placed in autogenous bone grafts and bone flaps in head and neck oncology patients: a systematic review   Abstract Using implants to retain prostheses as part of the oral rehabilitation of head and neck cancer patients is an increasingly common treatment modality, particularly in transported bone which is used to reconstruct defects following oncological surgical ...

Table 1 Implant characteristics—insertion region...

Patient Implant region(FDI) Implant parameters Dimensions of implantDiameter [mm]/length [mm] Explantation[Days after placement] 1 3637 First placementStraumannRN SLactive®(TiZr) First placementØ: 4.1; L: 10Ø: 4.1; L: 8 3   3637 Second placementStraumannTissue level(TiZr) Second placementØ :4.1, L: 8Ø :4.1, L: 8 3   36 Third placementConelog ScrewLine(...

Figure 2. a Patient 2. Postoperative orthopantomo...

  Figure 2. a Patient 2. Postoperative orthopantomogram one day after implant placement. b Patient 2. Postoperative orthopantomogram after second Implant placement

Figure 1. a Patient 1. Post grafting orthopantomo...

  Figure 1. a Patient 1. Post grafting orthopantomogram. The bone block was secured with a single microscrew. b Patient 1. The radiograph demonstrates veritable inserted Straumann bone level implants after the first implant placement (1 day after implant placement). A peri-implant osteolysis is not visible. c Patient 1. Postoperative orthopantomogram (1 day after implant placement) afte...

References : Vitamin D deficiency in early implant...

References Esposito M, Thomsen P, Ericson LE, Lekholm U. Histopathologic observations on early oral implant failures. Int J Oral Maxillofac Implants. 1999;14:798–810. Olmedo-Gaya MV, Manzano-Moreno FJ, Cañaveral-Cavero E, de Dios Luna-Del Castillo J, Vallecillo-Capilla M. Risk factors associated with early implant failure: a 5-year retrospective clinical study. J Prosthet Dent. 2016;115...

Discussion : Vitamin D deficiency in early implant...

However, a synergistic effect with other factors is conceivable. Some authors stated that implant osseointegration is not simply a wound healing phenomenon but rather complex foreign body reaction with activation of the immune system. Titanium and metal particle release is discussed as cause for implant failure as well as implant dentistry. It is assumed that metal particles influence the ma...

Discussion : Vitamin D deficiency in early implant...

However, a present human study cannot confirm an effect due to vitamin D supplementation on bone formation or graft resorption after maxillary sinus augmentation. Satue et al. found a positive influence of 7-dehydrocholesterol (7-DHC), the precursor of vitamin D, coated implants on osteoblast differentiation in vitro. But whether vitamin D-coated dental implants have an effect of osseo...

Discussion : Vitamin D deficiency in early implant...

Discussion This article demonstrated that implant placement was successful after vitamin D supplementation in patients with vitamin D deficiency and early failed implants. None of the patients showed systemic disease or did take regular medication, alcohol, nicotine, or drugs. The patients were not immunosuppressed, irradiated, or received chemotherapy. All implants were inserted with the s...

Case presentation : Vitamin D deficiency in early ...

After vitamin D supplementation and a healing period of 6 months, a third surgical intervention was planned and one implant (Conelog ScrewLine) was inserted in region 36 (see Table 1 and Fig. 1d). During implant placement, the former explantation site appeared clinically fully re-ossified. The patient received an intraoperative intravenous single-dose antibiotic therapy with Isocillin 1.2 mega. At...

Case presentation : Vitamin D deficiency in early ...

  Patient The medical history of this 48-year-old male patient showed a high blood pressure; otherwise, the patient was healthy. A successfully completed periodontal therapy was done before implant therapy. The patient demonstrated stable marginal bone levels. Autologous retromolar bone grafting using local anesthesia was performed in the left mandible (see Fig. 1a). This patient received a pos...

Case presentation : Vitamin D deficiency in early ...

Case presentation Patients and surgical procedure Patients treated consecutively in one center (Department of Oral- and Craniomaxillofacial Surgery, University Medical Center Freiburg). None of the patients showed systemic disease. Both patients did not take regular medication and were negative for alcohol, nicotine, and drug use. Bothe male patients (48 and 51 years of age) were not immunosu...

Background : Vitamin D deficiency in early implant...

Background Long-term stable osseointegrated implants are the primary goal in dental implantology. Although dental implants have proven clinical reliable in the long term, the failure of implants at a very early stage of osseointegration has been described. The pursuit to identify the mechanisms leading to early implant failure is ongoing to date and include the following: tobacco usage, diabete...

Vitamin D deficiency in early implant failure: two...

Abstract An association between vitamin D deficiency and early dental implant failure is not properly verified, but its role in osteoimmunology is discussed. This article illustrates two case reports with vitamin D deficiency and early implant failure. Prior to implant placement, the first patient received crestal bone grafting with autologous material. Both patients received dental implants fr...

Table 3 Articles excluded and reasons for exclusio...

Reason for exclusion Investigations Study design (case series or case report) Kim et al. (2017), Hatano et al. (2007) Different grafting technique (lateral sinus lift or transalveolar technique) Jensen et al. (1994), Winter et al. (2002), Toffler et al. (2004), Chappuis et al. (2009), Soltan et al. (2011), Xiao et al. (2011), Cricchio et al. (2011), Scala et al. (2012), Brus...

Table 2 Characteristics of the included investigat...

Author (year) Study design Follow-up (months) N of patients N of implants Smokers Length and diameter (mm) Implant system  Shihab 2017 Retrospective 60 35 70 NA 5–12 × 3.0–5.7 IDI FMD Nucleoss  Ghanem 2014 Retrospective 72 10 10 NA NA NA  Nooh 2013 Prospective 12 56 63 0 4 × 8 4.3 × 10 5 × 8 5 × 10 Nobel Biocare ...

Table 1 Clinical and radiographic complications re...

Clinical complications Radiographic complications Sinusitis Thickening of Schneiderian membrane Nasal bleeding, nasal obstruction, nasal secretion Bone reaction to the implants Headache and pain or tenderness in the region of the sinus Sinus pathology Decreased sense of smell  

Figure 4. Statistical analysis for different varia...

  Figure 4. Statistical analysis for different variables. a Weighted mean survival rate. b Implant survival rate according to degree of penetration. c Analysis of clinical complications. d Analysis of radiographic complications

Figure 3. Graphic representation of group 1 ≤ ...

  Figure 3. Graphic representation of group 1 ≤ 4 mm penetration and group 2 > 4 mm penetrations    

Figure 2. PRISMA flowchart of the screening proces...

  Figure 2. PRISMA flowchart of the screening process

Discussion : Influence of exposing dental implants...

The secondary outcome of this review was the analysis of the clinical and radiological complications related to the penetration of implants in the maxillary sinus. Clinical complication among the different authors ranges from 0 to 14.3%, with a weighted mean complication rate of 3.4%, without finding statistical difference according to the level of implant penetration. The most common clinic...

Figure 1. Graphic representation of implants intru...

  Figure 1. Graphic representation of implants intruding sinus perforating or not the Schneiderian membrane

Results : Influence of exposing dental implants in...

  Analysis of clinical complications Seven studies provide information on clinical complications with a global sample of 232 patients. Clinical complications among the different authors range from 0 to 14.3%, being the weighted mean complication rate 3.4% with an IC 95% [0 7.5] (Fig. 4c) Clinical complications analyzed in the studies were sinusitis, nasal bleeding, nasal obstruction, nasal sec...

Results : Influence of exposing dental implants in...

Results Study screening An initial screening yielded a total of 3551 publications of which 26 potentially relevant articles were selected after an evaluation of their titles and abstracts. Full text of these articles was obtained and evaluated thoroughly. Of these, eight articles (Table 2) fulfilled the inclusion criteria and subsequently were included in the qualitative analysis (Fig. 2). Re...

Materials & methods : Influence of exposing dental...

  Eligibility criteria Articles were included in this systematic review if they met the following inclusion criteria: human prospective or retrospective studies, reporting outcomes of implant placed perforating the sinus floor with implant burs, and without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material. The intrusion into the sinus cavity can occur du...

Materials & methods : Influence of exposing dental...

Materials and methods This systematic review and subsequent meta-analysis follow the guidelines of the PRISMA statement. Focus question The following focus question was developed: Is the intrusion of dental implants into the sinus cavity during implant drilling or implant placement, without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material, has an effec...

Introduction ; Influence of exposing dental implan...

Introduction The edentulous posterior maxillary region often presents with unique challenging conditions in implant dentistry. Limited bone height secondary to pneumatization of the maxillary sinus and the resorption of the alveolar ridge preclude in many instances the installation of dental implants. To compensate for the lack of bone height, several treatment options have been proposed. The ...

Influence of exposing dental implants into the sin...

Influence of exposing dental implants into the sinus cavity on survival and complications rate: a systematic review   Abstract Background After tooth loss, the posterior maxilla is usually characterized by limited bone height secondary to pneumatization of the maxillary sinus and/or collapse of the alveolar ridge that preclude in many instances the installation of dental implants. In order ...

Jepang membolehkan komersialisasi OCP/Col untuk be...

Setelah bertahun-tahun melakukan percobaan klinis, Jepang wusananya membolehkan komersialisasi OCP/Col untuk bedah oral. OCP/ Col kepanjangan dari Octacalcium Phospate/ Collagen. Selama 15 tahun pungkasan, Octacalcium Phosphate menjadi kandidat alternatif baru untuk menyediakan basis kristal mineral yang menyusun tulang dalam kombinasinya dengan kolagen. Bahan ini menjadi kandidat yang cenderung ...

Perawatan bone graft berapa lama?

Operasi bone graft-nya saja hanya berlangsung antara 1 sampai 2 jam, tergantung tingkat kesulitan kasus per individu pasien. Karena tubuh pasien tidak ada yang sama persis, maka lama operasi bone graft juga tidak ada yang sama persis.Setelah operasi selesai, Anda perlu waktu sampai bone graft jadi. Kasus yang paling ringan bisa sembuh hanya dalam waktu 2 minggu. Kasus yang paling berat bisa ...

Bone graft : teknologi abad 17 Masehi

Kesannya, bone graft itu teknologi baru. Padahal, perawatan ini ditemukan pertama kali pada sekitar pertengahan abad 17 Masehi, kira-kira 3,5 abad yang lalu.Sejarahnya, seorang dokter Belanda yang bernama Jacob van Meekeren merawat seorang pasien tentara dengan tengkorak kepala terbuka karena bertempur. Dokter mencari tulang apa yang bisa menyatu dengan tengkorak manusia. Singkat cerita, dokter ...

Alloplastic bone graft (Alloplast)

Bone graft alloplastis dikembangkan untuk mengatasi perkara yang berpotensi timbul dari penggunakan autograft. Alloplas terutama bersifat osteokonduktif tanpa potensi osteogenesis atau pun osteoinduksi.KeuntunganKeuntungan utama bahan alloplastis adalah:bahan baku tersedia berlimpah ruahtidak ada risiko transmisi penyakitantigenisitas sangat rendahdapat diproduksi dengan aneka bentuk dengan beraga...

Xenograft (Xenogenic bone graft)

Anda mungkin ingin pasang implant tapi dokter berkata, tulang rahang Anda tidak cukup besar untuk menopang implan. Jangan kuatir. Sekarang ada teknologi bone graft untuk memperbesar tulang penyangga implan. Asalkan kondisi tulang rahang Anda belum parah, tulang Anda masih bisa diperbesar dengan metode ini.Xenograft didefinisikan sebagai graft jaringan yang berasal dari spesies selain manusia. Misa...

Allograft (Allogenic bone graft)

Autograft dan allograft punya persamaan, yaitu sama-sama diambil dari manusia. Perbedaan di antara keduanya adalah autograf diambil dari tubuh pasien itu sendiri, sementara allograft diambil dari orang lain lalu dipasangkan pada pasien. Orang lain yang dimaksud bisa orang yang masih hidup atau orang yang sudah meninggal (kadaver). Alograft ada 3 jenis, yaitu:Tulang segar atau segar bekuFDBADFDBAT...

Autograft (autogenous bone graft)

Bone graft berbasis allograft menggunakan tulang allograft. Bone graft ini digunakan sendirian atau digunakan bersama-sama dengan materi lain. Kelebihan autograftKelebihan autograft meliputi:Autogenous bone graft memanfaatkan tulang yang diperoleh dari pasien itu sendiri.Rendahnya risiko penolakan graft oleh tubuh (reaksi imunologi), mengingat graft diambil dari tubuh pasien sendiri. Ini sebab...

Materi bone graft

Di bidang kedokteran gigi implan, materi bone graft merujuk pada materi yang ditanam dalam mulut pasien untuk meningkatkan pembentukan tulang baru melalui proses osteogenik, osteoinduktif, atau osteokonduktif. Osteogenik berarti materi bone graft mengandung sel-sel osteoprogenitor yang hidup dan yang mampu berdiferensiasi menjadi osteoblas sehingga menghasilkan tulang baru. Osteoinduktif berarti ...

Bone graft & implant gigi pada rahang menciut

Tanya:Tulang rahang saya sudah menciut. Apa masih bisa dipasangi implan?Jawab:Ada teknologi bone graft (cangkok tulang). Dengan teknologi masa kini, pasien yang mengalami penciutan tulang rahang masih punya kemungkinan untuk menerima implan. Hal itu tergantung pada seberapa parah penciutan yang terjadi, kualitas tulang, tebal tulang, dsb.Dokter akan memeriksa foto rontgen panoramik, foto 3D, atau...