Within the limits of this systematic review, the chairside method to harvest BMAC is a viable option for maxillary sinus augmentation for implant site development. The implant survival of the BMAC group was similar to the laboratory FICOLL concentration of BMAC group, without the additional cost and time of laboratory cell isolation techniques. Single or double centrifugation of BMAC does not appear to be a factor for new bone formation. The iliac crest or tibia origins for BMAC do not appear to be a factor for implant survival or bone formation. The use of BMAC can induce new bone formation comparable to control sites with no BMAC. However, the increase in new bone formation using chairside-harvested BMAC compared to controls with no BMAC is not predictably more significant across studies. In a clinical situation, new bone formation and regeneration in the maxillary sinus is not necessarily contingent on the presence of BMAC. And future studies should be directed at standardizing cell preparation methods and stains, as well as other parameters involved in wound healing of the maxillary sinus.