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Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [2]

Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [2]

author: Yuanhan Chang, Abhijit Anil Tambe, Yoshinobu Maeda, Masahiro Wada, Tomoya Gonda | publisher: drg. Andreas Tjandra, Sp. Perio, FISID

FEA studies with validation have recently become more common in the biomechanical field. FEA validations can be divided into two types: (1) direct validation, which involves experiments on the quantities of interest (from basic material characterizations to hierarchical system analysis such as model experiments and in vitro experiments), and (2) indirect validation, which involves the use of literature or the results of previous clinical studies. Indirect validation is clearly less favored than direct validation because of its uncertain experimental quality, sources of error, and high degree of variability. However, indirect validation may be unavoidable in FEA because no concrete biological outcome can be directly attributed to most FEA studies of force distribution; thus, it is difficult to generate outcome data for comparison with experimental data. Therefore, FEA studies should include a validation method to prove the close similarity of the results to the actual clinical situation. Validation is the process of “solving the right equations” [6,7,8,9] and comparing computational predictions with experimental data (the “gold standard”) in an effort to assess the modeling error.

The purpose of this literature review of FEA studies was to examine their model validation process and establish the criteria for evaluating validation methods with respect to their similarity to biological behavior.

All studies included in this review (eligibility criteria) were FEA studies of the stress distribution of dental implants and surrounding bone using any type of validation method, and all were published in English. The exclusion criteria were publication in a language other than English, appearance of the word “validation” only in the references, no mention of the validation method for numerical FEA analysis, and mentioning of the requirement for validation without conduction of the actual validation.

An electronic literature search of PubMed was conducted up to January 2017 using the Medical Subject Headings “dental implants” and “finite element analysis.” After accessing the full text, the full context was searched using the words “valid” and “validation,” and all articles containing these words were read to determine whether they met the inclusion criteria. The selected articles were then read and summarized, and the validation techniques used in each article were assessed and categorized in a hierarchy (Fig. 1).

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