Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [6]
Table 1 shows all studies in the literature that considered the need for validation of FEAs. According to these studies, we established a hierarchy based on the evidence level of the validations (A to G, i.e., high to low) (Fig. 2).
Level A: validation using living humans
Level B: validation using living heterogeneous animals
Levels C and D: validation using homogenous and heterogeneous bone
Level E: validation using artificial bone materials
Level F: validation using past literature
Level G: validation using other software
FEA using model verification cannot be considered to be a validation method for entire study. Model verification should be performed to ensure accurate FEA; however, finite element models verified with clinical data such as a patient’s computed tomography findings are categorized in a low level of validation or without validation. For this reason, studies that used only model verification (some studies may called it by "model validation") were not included in our review [58,59,60,61,62].
Many recent papers [10,11,12, 14, 15, 25,26,27,28,29,30,31, 33, 35, 36, 39, 41,42,43,44,45, 47, 48, 50,51,52, 54, 55, 58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74] have described the use of FEA to evaluate the stress distribution of implant fixtures and surrounding bone, with a particular focus on different fixture lengths, shapes, connection designs, and prostheses. However, most such studies [15, 58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74] were performed without validation executed under the same conditions with the FEA. The following questions are worthy of consideration by oral scientists and clinicians: Can a finite element model really create a virtual condition simulating the biomechanical behavior of the craniomandibular system? To what extent can we predict biological activities with finite element models [9]?
The complexity of living organisms and internal biological phenomena is impossible to fully and precisely duplicate with individual-level specificity using a computer. However, we can evaluate the limitations of current technology and build a model with the highest level of evidence possible.
Serial posts:
- Abstract : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [1]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [2]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [3]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [4]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [5]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [6]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [7]
- Review : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [8]
- Conclusions : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [1]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [2]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [3]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [4]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [5]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [6]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [7]
- References : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process [8]
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- About this article : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process
- Table 1 All studies in the literature that considered with an actual validation of FEA : Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process
- Fig. 1. Flowchart of literature review. An electronic literature search of PubMed was conducted up to January 2017 using the Medical Subject Headings “dental implants” and “finite element analysis.” After accessing the full texts, the context of each article was searched using the words “valid” and “validation” and articles in which these words appeared were read to determine whether they met the inclusion criteria for the review : Finite element analysis of dental implant
- Fig. 2. Hierarchy of validations based on their similarity to real biomechanical behaviors. The articles (n = 47) were categorized according to their validation method as follows: in vivo experiments in humans (n = 1) and other animals (n = 3), model experiments (n = 32), others’ clinical data and past literature (n = 9), and other software (n = 2) : Finite element analysis of dental implant
- Fig. 3. Proportion of dental implant FEA articles with a validation. (Left) Among totally 522 FEA articles of dental implants which we were able to access English full text up to January 2017, there are only 47 articles with a validation. (Right) The articles with a validation were categorized according to their validation method as follows levels: A, in vivo (human bodies); B, performed in vivo (heterogeneous animals); C, model experiment performed using part of a cadaver; D, model experiment performed using heterogeneous bone; E, model experiment performed using artificial materials; F, comparison with past literature; and G, performed with other software (n = 2) : Finite element analysis of dental implant