Figure 7. Post-operative occlusal photograph of the maxilla
Figure 6. Post-operative lateral view of the right maxillary arch
Figure 5. Post-operative lateral view of the left maxillary arch
Figure 4. Post-operative frontal view with teeth in occlusion
Date
Site number
Implant diameter (mm)
Implant length (mm)
Immediate load
Bone graft augmentation
3/26/14
12
4.3
10
Yes
Allograft
3/26/14
14
4.3
10
Yes
None
11/10/14
10
3.5
13
Yes
Allograft
3/5/15
7
3.5
13
Yes
Allograft
4/19/16
11
4.3
11.5
Yes
None
2/22/17
3
4.3
10
Yes
Allograft
2/22/17
4
5.0
10
Yes
Allograft
...
Figure 1. Characteristic blue sclerae
Table 1 Osteogenesis imperfecta classifications
Type
Inheritance
Gene
Locus
Clinical features
OMIM
I
AD
COL1A1 or COL1A2
17q21.33 or 7q21.3
Variable bone fragility, moderate bone deformity, blue sclerae, possible dentinogenesis imperfecta
166,200
II
AD
COL1A1 or COL1A2
17q21.33 or 7q21.3
Perinatally lethal
166,210
III
AD
COL1A1 or COL1A2
17q21....
References
Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfecta. J Med Genet. 1979;16:101–16.
Orioli IM, Castilla EE, Barbosa-Neto JG. The birth prevalence rates for the skeletal dysplasias. J Med Genet. 1986;23:328–32.
Stevenson DA, Carey JC, Byrne JL, Srisukhumbowornchai S, Feldkamp ML. Analysis of skeletal dysplasias in the Utah population. Am J Med Genet...
Discussion
The vast majority of published articles regarding OI type I revolve around fractures of the long bones and treatment strategies. An extensive literature search for manuscripts detailing the implant therapy for patients diagnosed with OI produced a marginal amount of literature (Table 3). Our case posits that oral restoration is attainable without implant failure for OI type I patien...
Surgical technique
The patient underwent implant therapy in stages under general anesthesia with immediate load protocol. Intravenous access was obtained, and the patient was anesthetized under general anesthesia by our anesthesiologist. Carpules of 2% lidocaine with 1:100,000 epinephrine, 4% articaine hydrochloride with 1:100,000 epinephrine (Septocaine), and 0.5% bupivacaine hydrochloride w...
Case presentation
Evaluation
A 53-year-old male diagnosed with OI type I was referred to our clinic for extraction of the remaining maxillary teeth and evaluation for full arch immediate load hybrid prosthesis. His clinical history included osteogenesis type 1, bipolar disorder, alopecia, and hypothyroidism. The patient presented with normal stature, measuring 170.18 cm and weighing 81.65 kg...
Introduction
Osteogenesis imperfecta (OI), colloquially known as “brittle bone disease,” is a broad term for a group of congenital disorders affecting the connective tissue resulting in a susceptibility to fractures. In 1979, Sillence et al. conducted an epidemiological and genetic study of OI patients [1]. These patients were grouped according to four distinct syndromes: (1) dominantly inh...
Implant therapy for a patient with osteogenesis imperfecta type I: review of literature with a case report
Abstract
Bone fragility and skeletal irregularities are the characteristic features of osteogenesis imperfecta (OI). Many patients with OI have weakened maxillary and mandibular bone, leading to poor oral hygiene and subsequent loss of teeth. Improvements in implant therapy have allowed f...