Author
Year
Study type
Selection bias (homogeneity and confounders)
Performance bias (fidelity to protocol)
Attrition bias (loss of participants)
Detection bias (reliable measures)
Reporting bias (selective reporting or conflict interests)
Summary assessment risk of bias
Alsaadi
2007
Retrospective
H
U
U
L
L
L
Aguilar-Salvatierra
2015
Prospective
H
L
L
L
L...
Table 1 List of the included studies and its main characteristics
Author
Year
Study type
Diabetes type
Control
Diabetes therapy
Glycemic control [HbA1c %]
Duration of diabetes (years)
Number of patients
Number of implants
Duration of study (years)
Implant survival [%]
Conclusion
Alsaadi
2007
Retrospective
Type II
Non-diabetes
n.d.
n.d.
n.d.
2004 (overall)
6...
Figure 1. Selection process of the included literature
References
Moraschini V, Poubel LA, Ferreira VF, Barboza Edos S. Evaluation of survival and success rates of dental implants reported in longitudinal studies with a follow-up period of at least 10 years: a systematic review. Int J Oral Maxillofac Surg. 2015;44(3):377–88.
Khader YS, Dauod AS, El-Qaderi SS, Alkafajei A, Batayha WQ. Periodontal status of diabetics compared with nondiabetics...
Conclusions
The literature included to this review is very heterogeneous concerning the investigated objects, methods, and conclusions. Diabetes is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. When looking at the complications and side effects resulting from diabetes, it is important to know which type of diabetes the pati...
While four studies conclude better implant survival and less peri-implant complications in the well-controlled group, the three others see no difference in implant success even in the poorly controlled patients. The study of Khandelwal treated exclusively patients with poor glycemic control (HbA1c 7.5–11.4 %) and had 98 % implant survival, after 4 months; therefore, he concluded that impla...
Diabetes and bone augmentation
We identified two prospective studies that evaluated “advanced” implant surgery covering sinus lift procedure and guided bone regeneration.
The study of Erdogan consists of type II diabetics moderately and well-controlled (HbA1c 6–7.5 %) with a mean duration of disease of 7.5 years and a healthy control group. Augmentation of the maxilla was perform...
The bleeding on probing is more often in the poorly controlled population, but the probing depth is not increased.
Diabetes and implant survival
Implant survival is an easily defined and measured endpoint for dental implant therapy. Nearly every study reports its implant survival rate. Our literature search identified 18 publications with these data. We divided them into two groups: the ...
The results in the prospective study of Gomez-Moreno show that elevated HbA1c causes more bone resorption after 3 years, but this effect is not significant.
We identified two prospective studies investigating the influence of type II diabetes on osseointegration.
They are published by the same author but are independent studies from different years. In both studies, the patients included...
Results
Study selection
There are no guidelines existing to the topic of dental implants and diabetes mellitus. A total of 327 potentially relevant titles and abstracts were found by the electronic search and additional evaluation of reference lists. During the first screening, 230 publications were excluded based on the title and keywords. Additionally, 24 titles were excluded based on abstract...
Materials and methods
The substructure of the systematic review is based on the PRISMA statement. The focused question according to the PICO schema is: “Do diabetic patients with dental implants have a higher complication rate in comparison to healthy controls?”
Search strategies
The systematic literature search was performed by an independent scientist (Burkhard Kunzendorf). The following ...
Review
Introduction
Today, dental implants are one of the restorative methods to replace missing teeth. Improvements in implant design, surface characteristics, and surgical protocols made implants a secure and highly predictable procedure with a mean survival rate of 94.6 % and a mean success rate of 89.7 % after more than 10 years. Implant survival is initially dependent on successful osseoi...
Abstract
Dental implant surgery has developed to a widely used procedure for dental rehabilitation and is a secure and predictable procedure. Local and systemic risk factors can result in higher failure rates. Diabetes mellitus is a chronic disease that goes in with hyperglycemia and causes multifarious side effects. Diabetes as a relative contraindication for implant surgery is controversially...
While four studies conclude better implant survival and less peri-implant complications in the well-controlled group, the three others see no difference in implant success even in the poorly controlled patients. The study of Khandelwal treated exclusively patients with poor glycemic control (HbA1c 7.5–11.4 %) and had 98 % implant survival, after 4 months; therefore, he concluded that implant the...
Diabetes and bone augmentation
We identified two prospective studies that evaluated “advanced” implant surgery covering sinus lift procedure and guided bone regeneration. The study of Erdogan consists of type II diabetics moderately and well-controlled (HbA1c 6–7.5 %) with a mean duration of disease of 7.5 years and a healthy control group. Augmentation of the maxilla was performed by g...
The bleeding on probing is more often in the poorly controlled population, but the probing depth is not increased.
Diabetes and implant survival
Implant survival is an easily defined and measured endpoint for dental implant therapy. Nearly every study reports its implant survival rate. Our literature search identified 18 publications with these data. We divided them into two groups: the first on...
We identified two prospective studies investigating the influence of type II diabetes on osseointegration. They are published by the same author but are independent studies from different years. In both studies, the patients included were stratified by HbA1c levels as well-controlled (HbA1c 6.1–8 %), moderately controlled (HbA1c 8.1–10 %), and poorly controlled (HbA1c ≥10 %).
The healthy...
Materials and methods
The substructure of the systematic review is based on the PRISMA statement. The focused question according to the PICO schema is: “Do diabetic patients with dental implants have a higher complication rate in comparison to healthy controls?”
Search strategies
The systematic literature search was performed by an independent scientist (Burkhard Kunzendorf). The follow...
Conclusions
The literature included to this review is very heterogeneous concerning the investigated objects, methods, and conclusions. Diabetes is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. When looking at the complications and side effects resulting from diabetes, it is important to know which type of diabetes the patient suffers from, if...
Results
Study selection
There are no guidelines existing to the topic of dental implants and diabetes mellitus. A total of 327 potentially relevant titles and abstracts were found by the electronic search and additional evaluation of reference lists. During the first screening, 230 publications were excluded based on the title and keywords. Additionally, 24 titles were excluded based on abstract...
Introduction
Today, dental implants are one of the restorative methods to replace missing teeth. Improvements in implant design, surface characteristics, and surgical protocols made implants a secure and highly predictable procedure with a mean survival rate of 94.6 % and a mean success rate of 89.7 % after more than 10 years. Implant survival is initially dependent on successful osseointegration...
Abstract
Dental implant surgery has developed to a widely used procedure for dental rehabilitation and is a secure and predictable procedure. Local and systemic risk factors can result in higher failure rates. Diabetes mellitus is a chronic disease that goes in with hyperglycemia and causes multifarious side effects. Diabetes as a relative contraindication for implant surgery is controversially...