Acknowledgements : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
Part of this study was supported by STDF reintegration grant number 489 and was performed in collaboration with the Oral Surgery Department, Faculty of Dentistry, Alexandria University, Egypt.
MNA prepared the specimens and performed the characterization process. He participated in preparation of histological section, data collection and analysis, and in preparation of the manuscript. RS performed the surgical phase of the study, provided animal care, looked after housing facilities, and participated in drafting the manuscript. Both authors read and approved the final manuscript.
Moustafa Aboushelib and Rehab Shawky declare that they have no competing interests.
Animal model was approved by the ethics committee of Alexandria University, Egypt, with authorization to publish on relevant data (STDF grant 489).
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Serial posts:
- Background : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [1]
- Background : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [2]
- Methods : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [1]
- Methods : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [2]
- Methods : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [3]
- Results : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
- Discussion : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [1]
- Discussion : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [2]
- Conclusions : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
- References : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [1]
- References : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles [2]
- Acknowledgements : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
- Author information : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
- Rights and permissions : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
- About this article : Osteogenesis ability of CAD/CAM porous zirconia scaffolds enriched with nano-hydroxyapatite particles
- Fig. 1. a SEM image, ×10,000, demonstrating internal porosity of the fabricated zirconia scaffolds. b SEM image, ×30,500, demonstrating agglomeration of nano-hydroxyapatite particles filling the porous structure : Osteogenesis ability of CAD/CAM porous zirconia sc
- Fig. 2. a Histological section demonstrating new bone growth (white arrow) in HA-enriched zirconia scaffold (black arrow). Unmineralized bone stained blue. Almost entire surface porosity was filled with new dense bone. b Histological section demonstrating bone growth in HA-enriched zirconia scaffold starting from the periphery of the surgical wound (white arrow). Islands of entrapped HA particles were surrounded by mineralized boney matrix (black arrow) which were identified using EDX : Osteogenesis ability of CAD/CAM porous zirconia sc
- Fig. 3. a Histological section demonstrating bone growth in control zirconia scaffold (white arrow). Mineralized bone formation (black arrow) was less dense compared to HA-enriched scaffolds. b Histological section showing different sizes of pores present in porous zirconia scaffolds (Control specimen). Mineralization started by lining pore walls (white arrow). Unmineralized bone stained blue : Osteogenesis ability of CAD/CAM porous zirconia sc
- Fig. 4. a Peri-apical X-ray of zirconia scaffold immediately placed in bone defect. Margins between scaffold and bone are clearly demarcated. b Peri-apical X-ray of zirconia scaffold after completion of healing time. Margins between bone defect and scaffold are less demarcated due to new bone growth : Osteogenesis ability of CAD/CAM porous zirconia sc