Background : Osseointegration of standard and mini dental implants (2)
Considerable confusion exists in the literature regarding the best method to monitor the status of a dental implant. Various methods have been used to demonstrate the osseointegration of dental implants. A common and time-tested method to evaluate biological responses to an implant is to measure the extent of bone implant contact (BIC), referred to as histomorphometry at the light microscopic level. Bone implant contact (BIC) is one of the parameters which has been used extensively to study the amount of bone apposition next to the implants. When an implant is placed in the jaw, it is in contact with compact bone as well as cancellous bone. The different structures of the two types of bone frequently result in variation of mineralized bone-to-implant contact length along the implant surface. Albrektsson et al. identified the key features affecting osseointegration about 4 decades ago, e.g., implant surface and topography, surface chemistry, charge, and wettability. Roughness and enhanced surface area seems to be helpful for osseointegration. Carlsson et al. reported that screw-shaped implants with a rough surface had a stronger bonding than implants with a polished surface. A coarse surface seems to be more appropriate for osseointegration of implants than a relatively smoother implant surface by representing a greater degree of implant integration. The bone contact areas of 3M™ESPE™ MDIs are surface treated. The treatment process of these MDIs includes sandblasting with aluminum oxide particles followed by cleaning and passivation with an oxidizing acid.
Despite the advantages of the mini dental implants, evidence on their efficacy and long-term success is lacking. The success of these implants will depend on their union with the surrounding bone. New implant systems entering into the market have to be studied with the help of animal models first, to demonstrate the osseointegration potential for their probable success in humans. There is a limited evidence regarding the 3M™ESPE™ MDIs. Therefore, there is a need for an animal study to explore the osseointegration of these implants to assist in better understanding of the treatment selection, prognosis, and outcomes for the patients.
Objectives of the study
The objective of this study is to compare bone apposition on the surface of mini dental implants and standard implants by means of histomorphometric methods.
Serial posts:
- Osseointegration of standard and mini dental implants: a histomorphometric comparison
- Background : Osseointegration of standard and mini dental implants (1)
- Background : Osseointegration of standard and mini dental implants (2)
- Methods : Osseointegration of standard and mini dental implants (1)
- Methods : Osseointegration of standard and mini dental implants (2)
- Methods : Osseointegration of standard and mini dental implants (3)
- Methods : Osseointegration of standard and mini dental implants (4)
- Methods : Osseointegration of standard and mini dental implants (5)
- Methods : Osseointegration of standard and mini dental implants (6)
- Results : Osseointegration of standard and mini dental implants
- Discussion : Osseointegration of standard and mini dental implants (1)
- Discussion : Osseointegration of standard and mini dental implants (2)
- Figure 1. Radiograph showing implants in the rabbit tibia
- Figure 2. Leica SP 1600 saw microtome
- Figure 3. Histological sections being obtained with Leica SP 1600 saw microtome
- Figure 4. Histological section of mini dental implant in rabbit tibia stained with methylene blue and basic fuchsin
- Figure 5. Histological section of standard implant in rabbit tibia stained with methylene blue and basic fuchsin
- Figure 6. Micro CT scan images of the MDIs and Ankylos® embedded in rabbit bone 6 weeks post implantation
- Table 1 Comparison of % BIC in both groups
- Table 2 Descriptive statistics of the experimental and control group