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Conclusions : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies

Conclusions : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies

author: Cassio Rocha Scardueli, Carolina Bizelli-Silveira, Rosemary Adriana C Marcantonio, Elcio Marcantonio Jr, Andreas Stavropoulos, R | publisher: drg. Andreas Tjandra, Sp. Perio, FISID

Based on the few studies included in this systematic review, it is possible to state that the systemic administration of Sr, in the form of SRAN, seems to enhance peri-implant bone quality and implant osseointegration, however, to a moderate extent. Further studies should focus on standardization of the study designs to properly assess the effects of Sr, including parameters such SRAN dose, administration start point, and duration of administration, further allowing the assessment of potential risks/benefits of SRAN use.

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