Table 2 Included studies and the evaluation methods employed, together with major outcomes for each method : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
Table 2 Included studies and the evaluation methods employed, together with major outcomes for each method : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
author: Cassio Rocha Scardueli, Carolina Bizelli-Silveira, Rosemary Adriana C Marcantonio, Elcio Marcantonio Jr, Andreas Stavropoulos, R | publisher: drg. Andreas Tjandra, Sp. Perio, FISID
Study
Tests and overall results
Bone mineral density
Histomorphometric
Biomechanical
MicroCT
Nanoindentation
Serum analysis
Maïmoun et al. 2010 [29]
_
_
SRAN > C
SRAN > C
(trabecular bone microarchitecture and BIC)
SRAN > C
(elastic modulus, tissue hardness, and working energy)
_
Li et al. 2010 [32]
_
_
OVX + SRH=CS > OVX + SRANL > OVX
OVX + SRANH > CS > OVX + SRANL > OVX
_
_
Li et al. 2012 [33]
_
OVX + SRAN > OVX
(BIC and BA)
OVX + SRAN > OVX
OVX + SRAN > OVX
_
OVX + SRAN > OVX
(OCN)
OVX + SRAN < OVX
(TRAP)
Linderbäck et al. 2012 [30]
BPA > SRAN=C
(4 and 8 weeks)
BPA > SRAN=C
(4 and 8 weeks)
BPA > SRAN=C
(4 and 8 weeks)
BPA > SRAN=C
(around implant)
BPA > SRAN > C
(growth plate)
_
_
Chen et al. 2013 [31]
BPZ = CS > BPA = SRAN > OVX
BPZ = CS > BPA = SRAN > OVX
BPZ = CS > BPA = SRAN > OVX
_
_
_
Table 2 Included studies and the evaluation methods employed, together with major outcomes for each method
Serial posts:
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Abstract : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Introduction : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
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Introduction : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
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Material and methods : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
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Material and methods : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
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Review : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
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Review : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
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Discussion : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
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Discussion : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
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Discussion : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [3]
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Conclusions : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Abbreviations : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
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References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
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References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [3]
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References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [4]
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References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [5]
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Author information : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
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Author information : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
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Ethics declarations : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Rights and permissions : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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About this article : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Table 1 Included studies and sample characteristics. Animal model, study groups, treatment start point and its duration, period of evaluation, implants specification, and evaluation methods : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Table 2 Included studies and the evaluation methods employed, together with major outcomes for each method : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Table 3 Assessment of risk of bias using SYRCLE’s tool : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
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Fig. 1. PRISMA flow diagram : Systemic administration of strontium ranelate to enhance the osseointegration of implant
| Study | Tests and overall results | |||||
|---|---|---|---|---|---|---|
| Bone mineral density | Histomorphometric | Biomechanical | MicroCT | Nanoindentation | Serum analysis | |
| Maïmoun et al. 2010 [29] | _ | _ | SRAN > C |
SRAN > C (trabecular bone microarchitecture and BIC) |
SRAN > C (elastic modulus, tissue hardness, and working energy) | _ |
| Li et al. 2010 [32] | _ | _ | OVX + SRH=CS > OVX + SRANL > OVX | OVX + SRANH > CS > OVX + SRANL > OVX | _ | _ |
| Li et al. 2012 [33] | _ |
OVX + SRAN > OVX (BIC and BA) | OVX + SRAN > OVX | OVX + SRAN > OVX | _ |
OVX + SRAN > OVX (OCN) OVX + SRAN < OVX (TRAP) |
| Linderbäck et al. 2012 [30] |
BPA > SRAN=C (4 and 8 weeks) |
BPA > SRAN=C (4 and 8 weeks) |
BPA > SRAN=C (4 and 8 weeks) |
BPA > SRAN=C (around implant) BPA > SRAN > C (growth plate) | _ | _ |
| Chen et al. 2013 [31] | BPZ = CS > BPA = SRAN > OVX | BPZ = CS > BPA = SRAN > OVX | BPZ = CS > BPA = SRAN > OVX | _ | _ | _ |
Table 2 Included studies and the evaluation methods employed, together with major outcomes for each method
- Abstract : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Introduction : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
- Introduction : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
- Material and methods : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
- Material and methods : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
- Review : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
- Review : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
- Discussion : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
- Discussion : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
- Discussion : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [3]
- Conclusions : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Abbreviations : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
- References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
- References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [3]
- References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [4]
- References : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [5]
- Author information : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [1]
- Author information : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies [2]
- Ethics declarations : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Rights and permissions : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- About this article : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Table 1 Included studies and sample characteristics. Animal model, study groups, treatment start point and its duration, period of evaluation, implants specification, and evaluation methods : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Table 2 Included studies and the evaluation methods employed, together with major outcomes for each method : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Table 3 Assessment of risk of bias using SYRCLE’s tool : Systemic administration of strontium ranelate to enhance the osseointegration of implants: systematic review of animal studies
- Fig. 1. PRISMA flow diagram : Systemic administration of strontium ranelate to enhance the osseointegration of implant