Comparing the present results to the aforementioned study with the same implant system on immediately placed implants, it seems that the GBR augmentation procedure has no influence on the long-term stability of the implants. In both studies with different placement modalities and protocols, comparable clinical and radiological results were achieved. This leads to the assumption that the investigated C-Tech bone level implant system is able to achieve long-term stable function and to render esthetically satisfying results for replacing missing teeth in cases of atrophy of the alveolar crest, as well as in cases of immediate implant placement.

However, the biomaterial-related tissue reaction is still not clarified in detail and more studies need to be performed to investigate the interaction of biomaterials, such as bone substitute materials and dental implants.