Implant size
Frequency
Percent
4.5 × 11
7
21.21
4...
Implant site
Frequency
Percentage
15
2
6.06
14
...
Variable
Number
Mean (percentage)
Standard deviation
Age (years)
16
...
May, M.C., Andrews, P.N., Daher, S. et al. Prospective cohort study of dental implant success rate in patients with AIDS.
Int J Implant Dent 2, 20 (2016). https://doi.org/10.1186/s40729-016-0053-3
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Received: 01 February 2016
Accepted: 12 July 2016
Published: 28 September 2016
DOI: https://doi.org/10.1186/s40729-016-0053-3
Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...
Triangle Implant Center, 5318 NC Highway 55, Suite 106, Durham, NC, 27713, USA
Michael Clayton May & Uday Nitin Reebye
University of North Carolina, Chapel Hill, NC, USA
Paul Nielsen Andrews
Boston University, Boston, MA, USA
Shadi Daher
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Kolhatkar S, Mason SA, Janic A, Bhola M, Haque S, Winkler JR. Surgical crown lengthening in a population with human immunodeficiency virus: a retrospective analysis. J Periodontol. 2012;83(3):344–53.
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United Nations AIDS Report. 2014. http://www.unaids.org/sites/default/files/media_asset/GARPR_2014_guidelines_en_0.pdf. Accessed 07 Oct 2015.
Centers for Disease Control and Prevention: Statistics. 2013. http://www.cdc.gov/hiv/statistics/basics/index.html. Accessed 09 Oct 2015.
Centers for Disease Control and Prevention: Statistics. 2011. http://www.cdc.gov/hiv/pdf/statistics_2011_hiv_surveillan...
Acquired immune deficiency syndrome
Cluster of differentiation 4
Centers for Disease Control and Prevention
Highly active antiretroviral therapy
Human immunodeficiency virus
Pneumocystis pneumonia
Our study found a slightly higher failure rate of 10 % in patients with AIDS, compared to widely accepted failure rates in healthy patients at 5–7 %. A cohort sample size of 33 may be considered small for statistical power; however, the results from this study could lead to larger future prospective cohort studies with additional funding to recruit a larger cohort and comparison groups. The ad...
Regarding dental procedures, a retrospective cross-sectional study of 101 HIV patients was done from 2003 to 2005. Complication rate was found to be 2.2 % overall and 4.8 % after invasive dental procedures. No relationship was found between complications and immunological values [14]. Another study examining healing response after surgical crown lengthening in 21 patients with HIV was analyzed, ...
Generally speaking, the use of antibiotics in dental implantology has been controversial. Amongst the reasons for early (preloading) implant failure are bacterial contamination, systemic disease, chemotherapy, overheating of bone, poor recipient site bone quality, and poor bone to implant contact upon surgery. After the prosthetic phase of the implant restoration, loading forces exceeding the bone...
Since the AIDS epidemic reared its head in the 1980s, the nature of this disease has quickly evolved from a devastatingly debilitating disease to one of chronicity. These patients are requesting for and are entitled to the optimal restorative treatment plans, many of which include dental endosteal implants. Several authors have delved into the realm of implantology in the HIV-positive patient, but...
Descriptive statistics are presented in Table 1. Sixteen (n = 16) patients met our inclusion criteria and were included in our study. The sample included 12 males and 4 females. The mean age at enrollment was 36.2 years (sd 8.83 years). The mean CD4 count at the time of placement was 141.25 (sd 35.5). A total of 33 implants were placed in the 16 patients, including 5 mandibular implants and...
Standard descriptive statistics were used to examine the distribution of key variables (age, gender, CD4 count at baseline and follow-up, and failure rate) in the sample. Due to the small sample size in this study (n = 16), the relationship of CD4 count and failure will be examined graphically and cases which failed are discussed individually in the “Results” section. A bar chart is presen...
Our study is a prospective study looking at the failure rates in root-formed implants in AIDS patients at 5 years post-surgical placement of the implant fixtures. Patients recruited for the study had to meet inclusion criteria which included diagnosis of AIDS measured by a pre-operative cluster of differentiation 4 (CD4)
The Joint United Nations Programme on HIV/AIDS estimates that 36.9 million (34.3–41.4 million) people are living with human immunodeficiency virus (HIV) infection [1]. In America, the Centers for Disease Control and Prevention (CDC) estimated that 1.2 million people aged 13 or older were HIV infected by the end of 2012 [2] and the cumulative population of persons surviving for more than 36 mont...
Oral health care of patients with acquired immune deficiency syndrome (AIDS) due to human immunodeficiency virus (HIV) is a growing area of concern, taking into consideration the increased life expectancy of patients resulting from antiretroviral therapy. There is insufficient literature regarding the impact of dental implants in AIDS patients. This study investigated the long-term clinical outcom...
Figure 2. Number of implants and failures by quartiles of CD4
Figure 1. Kaplan-Meier survival curve for individual implants, n = 33
Table 3 Frequency table of implant size
Implant size
Frequency
Percent
4.5 × 11
7
21.21
4.5 × 8
1
3.03
4 × 11
10
30.3
4 × 8
13
39.39
5 × 11
1
3.03
5 × 8
1
3.03
Total
33
100
Table 2 Frequency table of implant site
Implant site
Frequency
Percentage
15
2
6.06
14
1
3.03
13
3
9.09
12
4
12.12
11
7
21.21
21
4
12.12
22
1
3.03
23
3
9.09
24
1
3.03
25
2
6.06
35
1
3.03
33
1
3.03
43
1
3.03
45
1
3.03
46
1
3.03
Total
33
100
Table 1 Descriptive statistics (n = 16 patients)
Variable
Number
Mean (percentage)
Standard deviation
Age (years)
16
36.19
8.83
Sex
Male
12
(75)
–
Female
4
(25)
–
CD4 count (cells/mm3)
16
141.25
35.5
No. of implants
33
–
–
No. of implants that failed
3
(9.1) (% failed)
–
Average time to failure (days)
29.7
–
...
Discussion
Since the AIDS epidemic reared its head in the 1980s, the nature of this disease has quickly evolved from a devastatingly debilitating disease to one of chronicity. These patients are requesting for and are entitled to the optimal restorative treatment plans, many of which include dental endosteal implants. Several authors have delved into the realm of implantology in the HIV-pos...
Results
Descriptive statistics are presented in Table 1. Sixteen (n = 16) patients met our inclusion criteria and were included in our study. The sample included 12 males and 4 females. The mean age at enrollment was 36.2 years (sd 8.83 years). The mean CD4 count at the time of placement was 141.25 (sd 35.5). A total of 33 implants were placed in the 16 patients, including 5 mandibular imp...
Methods
Our study is a prospective study looking at the failure rates in root-formed implants in AIDS patients at 5 years post-surgical placement of the implant fixtures. Patients recruited for the study had to meet inclusion criteria which included diagnosis of AIDS measured by a pre-operative cluster of differentiation 4 (CD4)
Background
The Joint United Nations Programme on HIV/AIDS estimates that 36.9 million (34.3–41.4 million) people are living with human immunodeficiency virus (HIV) infection. In America, the Centers for Disease Control and Prevention (CDC) estimated that 1.2 million people aged 13 or older were HIV infected by the end of 2012 and the cumulative population of persons surviving for more than 36...
Abstract
Background
Oral health care of patients with acquired immune deficiency syndrome (AIDS) due to human immunodeficiency virus (HIV) is a growing area of concern, taking into consideration the increased life expectancy of patients resulting from antiretroviral therapy. There is insufficient literature regarding the impact of dental implants in AIDS patients. This study in...