Xenograft Bone Substitute (3)
From the perspective of the clinician, it is difficult to distinguish between good and unsatisfactory histologic results following bone grafting procedures when compared to clinical findings. When performing an osteotomy, clinicians are compelled to classify the specific density of the newly produced tissue because the biopsy results typically take a few days to weeks to obtain. For instance, while assessing the long-term prognosis of a particular patient, clinicians can be perplexed by the correlation between clinically good or well findings and histologically negative or doubtful outcomes. To classify the various degrees of remodeling pattern of the newly produced tissue, it is strongly advised to refer to Kim and Lee's (2017) paper. Based on the degree of grafting material activity on osteogenic bony induction, the degree of mesenchymal organization, the quantity of inflammatory cell infiltration, and the pattern of trabecular bone anastomosis, the biopsy results are classified into one of five distinct remodeling patterns, as indicated in Table 2.
Table 2 . Classification of bone remodeling for implant site development (SK Lee, 2017)28)
| Classification | Histological findings |
|---|---|
| Excellent bony remodeling | 1. Osteogenic bony induction is active 2. Cancellous bones are anastomosed with thick trabecular bones 3. Loose connective tissue without infiltration of inflammatory cells |
| Favorable bony remodeling | 1. Osteogenicbony induction is active, but incomplete 2. Cancellous bones are anastomosed, but immature 3. Loose connective tissue without infiltration of inflammatory cells |
| Partial bony remodeling | 1. Osteogenic bony induction may be present occasionally and grafting materials rarely produce new bones 2. Infiltration of inflammatory cells are seen in stromal tissues |
| Degenerative bony remodeling | 1. No new bone formation is found around the grafting materials 2. Marked infiltration of chronic inflammatory cells 3. Stromal fibrous tissue may be edematous and degenerative |
| Poor bony remodeling | 1. The grafting materials do not induce any osteo-inductive effect, nor osteo-conductive effect on the marrow tissue 2. Most of grafting materials are scattered and surrounded by fibrous tissue 3. Sclerotic collagen bundles are deposited and the stromal fibrosis may be severe to encircle and separate the grafting materials 4. Throughout the lesion there is no evidence of inflammatory reaction |
Serial posts:
- Autogenous Bone Graft (3)
- Cangkok Tulang Gigi Autogen (3)
- Autogenous Tooth Bone Graft (3)
- Xenograft Bone Substitute (3)