Discussion : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [3]
Vogel and Marcotte [33] suggested that the correlation between mRNA and protein quantities is approximately 40%. As there are many mechanisms between transcription and translation, especially in human cell and protein stability, at the gene expression level, the transcription data is beneficial in making decisions about molecular candidates for future studies at the protein level. The colorimetric assay and ELISA techniques utilized in this study have many advantages, such as sensitivity, specificity, speed, and compatibility with standard clinical laboratory equipment [34]. These techniques can be routinely applied in clinical situations. Although the high sensitivity and specificity of the quantitative, real-time, polymerase chain reaction are justified [35], the limitations of this technique are the sensitive nature of the work and the cost of the chemicals and equipment.
Serial posts:
- Background : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [1]
- Background : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [2]
- Methods : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [1]
- Methods : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [2]
- Methods : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [3]
- Methods : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [4]
- Results : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [1]
- Results : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [2]
- Discussion : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [2]
- Discussion : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [3]
- Conclusions : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- References : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [1]
- References : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [2]
- References : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [3]
- References : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study [4]
- Acknowledgements : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Author information : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Rights and permissions : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- About this article : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Table 1 Inclusion and exclusion criteria : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Table 2 Profile of patients : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Table 3 ISQ values according to gender and bone quality : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Table 4 Crevicular fluid volume : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Table 5 Crevicular fluid ALP and OC levels : Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study
- Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth : Relation between the stability of dental implant
- Fig. 2. Change in the mean ISQ values over time. There was a statistically significant decrease in the mean ISQ values between 1 and 3 weeks (P < 0.05). The ISQ values recovered to the initial ISQ values at 4 weeks and slight increased at 6, 8, 10, and 12 weeks : Relation between the stability of dental implant
- Fig. 3. Change in the median values of the GCF (control group) and PICF (test group) volume over time. In the test group, the PICF volume continuously decreased with time (a). There were no significant differences in the median values of the crevicular fluid volume in either the control group or the test groups at any measurement (b) : Relation between the stability of dental implant
- Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level decreased at 1–4 weeks and then increased at 6, 8, 10, and 12 weeks. There was no statistically significant difference in the ALP level in either the control or the test groups at any measurement : Relation between the stability of dental implant
- Fig. 5. Change in the median values of the OC level over time. In the test group, the OC level continuously increased with time. There was a statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P < 0.05) : Relation between the stability of dental implant
- Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all measurements from week 1 to week 12. At the implant site, the ALP levels in nM/μg protein (a) or the OC levels in pg/μg protein (b) were associated with ISQ values : Relation between the stability of dental implant
- Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time : Relation between the stability of dental implant
- Fig. 8. There were moderately significant and positive correlations between the ALP levels and OC levels at all measurements from week 1 to week 12. The OC levels in pg/μg protein were associated with the ALP levels in nM/μg protein at the implant site (a), control site (b), and pooled samples of the control and implant sites (c) : Relation between the stability of dental implant