Table 4 Implant loss and tissue characteristics : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
Table 4 Implant loss and tissue characteristics : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
author: Alberto Ortiz-Vign, Sergio Martinez-Villa, Iaki Suarez, Fabio Vignoletti, Mariano Sanz | publisher: drg. Andreas Tjandra, Sp. Perio, FISID
Differentiated tissues
Implant lost (Yes/no)
Mean
SD
Percentage
SD (%)
Significance (p < 0.05)
Mineralized bone
No
*3.5 × 10
6
5.1 × 105
30.84
7.39
p = 0.01
u
Yes
1.3 × 10
6
1.2 × 106
18.84
17.31
Connective tissue
No
1.8 × 106
1.9 × 106
*15.51
16.15
p = 0.01
t
Yes
4.6 × 106
3.7 × 106
46.52
19.14
Bone marrow
No
*3.7 × 10
6
1.9 × 106
*31.91
15.49
p = 0.02
t
Yes
1.0 × 10
6
9.2 × 105
13.48
11.24
CCXBB
No
2.5 × 106
1.2 × 106
20.92
7.46
p = 0.98t
Yes
2.0 × 106
1.4 × 106
20.82
8.22
TRAP
No
-
-
3.99
4.53
p = 0.24u
Yes
7.57
5.47
OPN
No
-
-
6.71
4.06
p = 0.11t
Yes
11.29
5.11
ALP
No
-
-
2.24
2.15
p = 0.09u
Yes
0.24
0.18
OSC
No
-
-
*2
2.05
*p = 0.02
u
Yes
8.78
4.65
Table 4 Implant loss and tissue characteristics
Serial posts:
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Abstract : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
-
Background : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
-
Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
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Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
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Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [3]
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Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [4]
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Results : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
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Results : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
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Discussion : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
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Discussion : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
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Discussion : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [3]
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Conclusions : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Abbreviations : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
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References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
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References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [3]
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References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [4]
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References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [5]
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Acknowledgements : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
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Acknowledgements : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
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Author information : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Rights and permissions : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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About this article : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Table 1 Clinical and histomorphometry assessments (i.e., dehiscences, mineralized bone, CCXBB, bone marrow, connective tissue, and implant lost) : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Table 2 Quantitative histological analysis : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Table 3 Immunohistochemical markers proportions (i.e., TRAP, OPN, ALP, and OSC) : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Table 4 Implant loss and tissue characteristics : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
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Fig. 1. Study chart and follow-up visits : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
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Fig. 2. Lateral bone augmentation of the alveolar crest (a) atrophic ridge. b Perforations and adaptation of the cortical layer. c Shaping, pre-wetting and fixation of CCXBB with titanium screws. d Horizontal contour and peripheral gap between CCXBB and bone layer. e Outlying DBBM filling. f CM stabilized with pins : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
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Fig. 3. Re-entry procedure of patient in Fig. 1. a Buccal aspect of the augmented region. b Horizontal bone augmentation. c Screws and pins removal and bone trephine sampling. d Implants placement and buccal bone width from the implant shoulder. e Primary flap closure. f Implants submerged healing : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
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Fig. 4. Histological samples. a CCXBB control without implantation. b Histologic samples with acute inflammatory infiltration. c Histologic sample with limited remaining CCXBB and large bone ingrowth : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
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Fig. 5. Histomorphometric analysis of the same sample. a Ground section stained with Levai-Laczkó. b Tissue identification of the ROI. c Closer view aarrow pointing a cement line between new mineralized bone and CCXBB. d Closer view of b : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
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Fig. 6 Immunohistochemical analysis of slices from the same sample with four different markers. a TRAP. b OPN. c ALP. d OSC
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Fig. 7 Second stage surgery of patient in Fig. 1. a Vestibular depth reduction after augmentation and implant placement. b Partial thickness and apical repositioned flap. c CMX healing and soft tissue dehiscence with CCXBB exposure. d Dehiscence healing after re-contouring and buccal emergency profile. e Buccal aspect of the final restoration. f Buccal ridge contour
| Differentiated tissues | Implant lost (Yes/no) | Mean | SD | Percentage | SD (%) | Significance (p < 0.05) |
|---|---|---|---|---|---|---|
| Mineralized bone | No | *3.5 × 10 6 | 5.1 × 105 | 30.84 | 7.39 | p = 0.01 u |
| Yes | 1.3 × 10 6 | 1.2 × 106 | 18.84 | 17.31 | ||
| Connective tissue | No | 1.8 × 106 | 1.9 × 106 | *15.51 | 16.15 | p = 0.01 t |
| Yes | 4.6 × 106 | 3.7 × 106 | 46.52 | 19.14 | ||
| Bone marrow | No | *3.7 × 10 6 | 1.9 × 106 | *31.91 | 15.49 | p = 0.02 t |
| Yes | 1.0 × 10 6 | 9.2 × 105 | 13.48 | 11.24 | ||
| CCXBB | No | 2.5 × 106 | 1.2 × 106 | 20.92 | 7.46 | p = 0.98t |
| Yes | 2.0 × 106 | 1.4 × 106 | 20.82 | 8.22 | ||
| TRAP | No | - | - | 3.99 | 4.53 | p = 0.24u |
| Yes | 7.57 | 5.47 | ||||
| OPN | No | - | - | 6.71 | 4.06 | p = 0.11t |
| Yes | 11.29 | 5.11 | ||||
| ALP | No | - | - | 2.24 | 2.15 | p = 0.09u |
| Yes | 0.24 | 0.18 | ||||
| OSC | No | - | - | *2 | 2.05 | *p = 0.02 u |
| Yes | 8.78 | 4.65 |
Table 4 Implant loss and tissue characteristics
- Abstract : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Background : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
- Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
- Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [3]
- Methods : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [4]
- Results : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
- Results : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
- Discussion : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
- Discussion : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
- Discussion : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [3]
- Conclusions : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Abbreviations : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
- References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
- References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [3]
- References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [4]
- References : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [5]
- Acknowledgements : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [1]
- Acknowledgements : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement [2]
- Author information : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Rights and permissions : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- About this article : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Table 1 Clinical and histomorphometry assessments (i.e., dehiscences, mineralized bone, CCXBB, bone marrow, connective tissue, and implant lost) : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Table 2 Quantitative histological analysis : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Table 3 Immunohistochemical markers proportions (i.e., TRAP, OPN, ALP, and OSC) : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Table 4 Implant loss and tissue characteristics : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement
- Fig. 1. Study chart and follow-up visits : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
- Fig. 2. Lateral bone augmentation of the alveolar crest (a) atrophic ridge. b Perforations and adaptation of the cortical layer. c Shaping, pre-wetting and fixation of CCXBB with titanium screws. d Horizontal contour and peripheral gap between CCXBB and bone layer. e Outlying DBBM filling. f CM stabilized with pins : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
- Fig. 3. Re-entry procedure of patient in Fig. 1. a Buccal aspect of the augmented region. b Horizontal bone augmentation. c Screws and pins removal and bone trephine sampling. d Implants placement and buccal bone width from the implant shoulder. e Primary flap closure. f Implants submerged healing : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
- Fig. 4. Histological samples. a CCXBB control without implantation. b Histologic samples with acute inflammatory infiltration. c Histologic sample with limited remaining CCXBB and large bone ingrowth : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
- Fig. 5. Histomorphometric analysis of the same sample. a Ground section stained with Levai-Laczkó. b Tissue identification of the ROI. c Closer view aarrow pointing a cement line between new mineralized bone and CCXBB. d Closer view of b : Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant
- Fig. 6 Immunohistochemical analysis of slices from the same sample with four different markers. a TRAP. b OPN. c ALP. d OSC
- Fig. 7 Second stage surgery of patient in Fig. 1. a Vestibular depth reduction after augmentation and implant placement. b Partial thickness and apical repositioned flap. c CMX healing and soft tissue dehiscence with CCXBB exposure. d Dehiscence healing after re-contouring and buccal emergency profile. e Buccal aspect of the final restoration. f Buccal ridge contour