The aim of the present paper is to evaluate a simplified implant site preparation technique to preserve bone bulk and enhance osseointegration using a new conical self-tapping implant in cancellous bone.

Ten Expander® 3.8 × 10 mm implants (NoDrill®, Milano, Italy) were inserted in the right side (test group) of sheep’s iliac crest using only the pilot drill 1.8 mm in diameter. Ten 3.8 × 10 mm Dynamix® implants (Cortex, Shlomi, Israel) were inserted in the right side (control group) of the same animals following the drilling protocol provided by the manufacturer. Histological, histomorphometric, and biomechanical analyses were performed after 2 months.

Implants that belonged to the test group showed a %BIC of 70.91 ± 7.95 while the control group implants had a %BIC value of 49.33 ± 10.73. The %BV was 41.83 ± 6.30 in the test group and 29.61 ± 5.05 in the control group. These differences were statistically significant. A phenomenon of osseocorticalization, characterized by more bone volume percentage around implant area than in the neighboring areas, caused by implant threads geometry, was evident in the test group.

This surgical protocol allows to insert an innovative fixture geometry in low-density bone using only a pilot drill. This technique demonstrated many clinical and histological advantages with respect to standard implant drilling procedures and classical implant geometry.