Mean scores of all clinical indices for each subject were calculated separately for dental implants and natural teeth. The final data analysis was performed for those subjects who completed the study. The Student’s t test and the Mann-Whitney U test were used to evaluate whether any statistically significant differences were present between the two groups at each time point, and the Wilcoxon signed-rank test was performed to verify if any statistically significant changes occurred from baseline within each group. A total sample size of 74 patients (37 per group) achieves 81% power to detect a difference of 0.2 between the differences of group means with group standard deviations of 0.3. P values < 0.05 were considered statistically significant.