The difference between the BoP recorded on dental implant sites at baseline and the end of the study showed statistical significance for both the test and control groups (P < 0.0001) (Fig. 5). Analyzing in detail the 1–3-month period, it was observed how only the test group showed a statistical significance (P < 0.0001) while the control lost it (P = 0.709). At 3 months, no significative differences between the two groups were observed (P = 0.564).

Analog situation could be observed in Fig. 6, representing BoP around the natural teeth. In this case, the difference with the baseline were significant for both groups (P < 0.0001 and P = 0.007 respectively for test and control). In the second part of the observation period (1–3-month period), it was possible to detect an increase for the control (P = 0.342) while the test kept decreasing, even if slightly (P < 0.05; P = 0.0021). The comparison between the test and control groups after 3 months showed a statistical significance (P < 0.05).

No differences during the time points were observed in both test and control groups as clearly shown in Figs. 7 and 8. It was possible to observe a reduction of PPD of 0.15 mm between the beginning and end of the study around dental implants on both test and control groups.