Osseointegration of TI6Al4V dental implants
Osseointegration of TI6Al4V dental implants modified by thermal oxidation in osteoporotic rabbits
Abstract
Background
In this work, the effect of the heat treatment on Ti6Al4V implants and topical administration of growth hormone to address a better osseointegration in osteoporotic patients has been analysed.
Methods
The osseointegration process of Ti6Al4V implants modified by oxidation treatment at 700 °C for 1 h and the influence of local administration of growth hormone (GH) in osteoporotic female rabbits after 15 and 30 days of implantation have been studied. Bone response was analysed through densitometric and histomorphometric studies. Characterization of the surface was provided by scanning electron microscopy.
Results
The oxidation treatment promotes the formation of an oxide scale grown on the Ti6Al4V implants that alters the nanoroughness of the surface. Bone mineral density (BMD) increases from 0.347 ± 0.014 (commercial) to 0.383 ± 0.012 g cm−2 (modified), and bone-to-implant contact (BIC) goes from 48.01 ± 14.78 (commercial) to 55.37 ± 15.31 (modified) after 30 days of implantation.
Conclusions
The oxidation treatment on the Ti6Al4V dental implants enhances the early bone formation at the longest periods of implantation. No significant differences in the BMD and BIC results in healthy and osteoporotic rabbits were revealed with respect to the local administration of GH in the implantation site.
Serial posts:
- Osseointegration of TI6Al4V dental implants
- Background : Osseointegration of TI6Al4V dental implants
- Methods : Osseointegration of TI6Al4V dental implants (1)
- Methods : Osseointegration of TI6Al4V dental implants (2)
- Methods : Osseointegration of TI6Al4V dental implants (3)
- Methods : Osseointegration of TI6Al4V dental implants (4)
- Methods : Osseointegration of TI6Al4V dental implants (5)
- Results : Osseointegration of TI6Al4V dental implants (1)
- Results : Osseointegration of TI6Al4V dental implants (2)
- Results : Osseointegration of TI6Al4V dental implants (3)
- Discussion : Osseointegration of TI6Al4V dental implants (1)
- Discussion : Osseointegration of TI6Al4V dental implants (2)
- Discussion : Osseointegration of TI6Al4V dental implants (3)
- References : Osseointegration of TI6Al4V dental implants
- Figure 1. Schematic diagram of the classification of experimental animals in groups
- Figure 2. Transcortical osteotomy with Ti6Al4V implant inserted in the tibia bone
- Figure 3. SEM image of the surface of control commercial Ti6Al4V dental implants
- Figure 4. SEM image of the nanoroughness of the oxidized surfaces on control Ti6Al4V dental implants after 700 °C for 1 h
- Figure 6. Bone to implant contact (BIC) values (%) for commercial
- Table 1 Chemical analysis by EDAX of the surface of Ti6Al4V commercial implants
- Table 2 Mean (grammes per square centimetre) and standard deviations
- Table 3 Means and standard deviations of the bone mineral density