A Growing Connection Between Oral and Brain Health
Recent scientific advancements have uncovered a fascinating—and potentially game-changing—link between periodontal (gum) disease and neurodegenerative conditions like Alzheimer’s disease. While the relationship remains an active area of research, emerging evidence suggests that maintaining optimal oral health may play a crucial role in su...
Why Scaling and Root Planing Matters for Your Oral Health
Scaling and root planing (SRP) is a deep-cleaning dental procedure designed to treat periodontal disease by removing bacterial plaque and calculus from both the tooth surface and below the gumline. This non-surgical therapy is essential for halting gum inflammation, preventing tooth loss, and maintaining long-term oral health. While it m...
Gum inflammation, or gingivitis, is a common yet often overlooked oral health concern that can progress to more serious conditions if left untreated. While conventional dental care remains the gold standard, many patients seek natural remedies to complement their routine. However, not all home treatments are evidence-backed or safe—especially for those with dental implants or compromised gum hea...
Gum health is the foundation of a radiant smile and long-term oral well-being. While brushing remains essential, interdental cleaning —particularly with floss—plays a critical role in preventing gingival recession , periodontal disease, and bone loss. When executed correctly, flossing removes plaque and bacteria from areas your toothbrush can’t reach, preserving your gum tissue and suppo...
Treatment arrangement and ground
The patient was first referred to the school of hygiene to treat the gum inflammation and improve his oral care. The treatment was planned in two main stages. In the first stage, the goal was to use growth to reduce the overjet, get the molars and canines into a normal Class I relationship, and create more room for the missing front tooth. This was done using a Tw...
Discussion
Complex tissue engineering concepts have to be evaluated in terms of their clinical applicability. Thus, the overall goal should be to establish a method that could ideally be completed within a short time span before or during intended regenerative surgical procedures. Over the last few years, Choukroun's PRF has proven to be a method that comes close to the ideal concept of guide...
Results
Histochemical studies (H&E, Mason-Goldner, and Giemsa)
S-PRF
In the longitudinal section of the S-PRF clot, produced according to the standard centrifugation protocol (2700 rpm, 12 minutes), a dense fibrin clot was seen with minimal interfibrous space. With the standard histochemical staining methods, cells were observed throughout the clot, albeit decreasing toward the more distal ...
Production of Choukroun's PRF
The PRF scaffolds were prepared according to a previously published protocol.11,26 Four healthy (ie, with no history of anticoagulant usage) volunteers in an age range between 18 to 60 years participated in this study. For each individual, 4 tubes of peripheral blood were collected and immediately placed in a preprogrammed centrifuge (PC-O2, PROCESS for PRF, N...
A major objective of biomaterial research and tissue engineering is to promote a material-induced tissue reaction that leads to regeneration and an effective wound-healing process in the defective area. Thus, a biomaterial should serve as a temporary barrier to cover defects and promote tissue regeneration while being tissue compatible and, most importantly, clinically applicable. In the field o...
Advanced Platelet-Rich Fibrin: A New Concept for Cell-Based Tissue Engineering by Means of Inflammatory Cells
Shahram Ghanaati, MD, DMD; Patrick Booms, PhD; Anna Orlowska, BSc, DVM; Alica Kubesch; Jonas Lorenz, DDS; Jim Rutkowski, DMD, PhD; Constantin Landes, MD, DMD, PhD; Robert Sader, MD, DDS, PhD; CJ Kirkpatrick, MD, PhD, DSc; Joseph Choukroun, MD
J Oral Impla...