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Model masa kini interaksi inang-mikroba pada pathogenesis periodontitis, di mana tanggapan inang menggerakkan disbiosis yang baru (gingivitis).

Figure 1. Pathogenesis of periodontitis

author: Shinya Murakami, Brian L Mealey, Angelo Mariotti, Iain LC Chapple | publisher: drg. Andreas Tjandra, Sp. Perio, FISID
Figure 1. Contemporary model of host–microbe interactions in the pathogenesis of periodontitis
Figure 1. Contemporary model of host–microbe interactions in the pathogenesis of periodontitis

 

Model masa kini interaksi inang-mikroba pada pathogenesis periodontitis, di mana tanggapan inang menggerakkan disbiosis yang baru (gingivitis). Jika biofilm tidak diganggu/ dihapus, disbiosis terang-terangan metuken dan melanggengkan peradangan kronis yang tidak terselesaikan dan merusak.
 

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DAMP Damage‐Associated Molecular Patterns, pola molekul yang terkait kerusakan
PMN polymorphonuclear neutrophils, neutrofil polimorfonuklear
MMP matrix metalloproteinases, matrix metalloproteinases
LPS lipopolysaccharide, lipopolisakarida
GCF gingival crevicular fluid, cairan crevicular gingiva
N-fMLP, N-formylmethionyl-leucyl-phenylalanine;