This publication is made possible due to the generosity and support from senior faculties of the Department of Periodontics, RSDM. They are Dr. Howard Drew, vice chairman of Department of Periodontics, Dr. Emil Cappetta, Director of Postgraduate Program, and Dr. Joel Pascuzzi, Director of the Undergraduate Periodontal Program. Particularly, Dr. Michael Conte, Senior Associate Dean for the Office of Clinical Affairs, RSDM, provided us with lab space and instruments to initiate the experiment. And Dr. Edward Yurkow, Executive Director of Molecular Imaging and Pharmacology, helped us for micro-CT analysis. The views expressed in this paper are those of the authors and do not necessarily reflect the views or policies of the affiliated organizations. Authors confirm that they have no financial involvement with any commercial company or organization with direct financial interest regarding the materials used in this study. Special Thanks to Dr. H Afsar Lajevardi Foundation for endless support.