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Fig. 5. PROMs over 5 years: improvement of satis...

Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end

Fig. 4. Soft tissue parameters at 5-year post-load...

Fig. 4. Soft tissue parameters at 5-year post-loading. a Plaque index: score 0, no plaque detected; score 1, plaque only recognized by running a probe across the smooth marginal surface of the implant; score 2, plaque seen by the naked eye; score 3, abundance of soft matter. b Sulcus bleeding index: score 0, no bleeding when a periodontal probe was passed along the gingival margin adjacent to th...

Fig. 3. Standardized peri-apical radiographs repre...

Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5-year post-loading (c) Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5...

Fig. 2. Kaplan-Meier cumulative survival rate : Cl...

Fig. 2. Kaplan-Meier cumulative survival rate Fig. 2. Kaplan-Meier cumulative survival rate

Fig. 1. Study flow-chart: assessments and reason f...

Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits

Table 3 Mean crestal bone level changes in mm : Cl...

Bone level changenMeanSDInsertion-loading103− 0.520.55Loading-1-year follow-up93− 0.040.37Loading-3-year follow-up90− 0.040.40Loading-5-year follow-up86− 0.090.43Table 3 Mean crestal bone level changes in mm

Table 2 Demography of study population : Clinical ...

CharacteristicsCategoryTotalTotal patients/implantsn94/130Center 19/17Center 218/26Center 320/26Center 414/16Center 518/26Center 615/19Gender, n (%)Male30 (31.9)Female64 (68.1)Age at surgery, yearsMean ± SD50.4 ± 13.7Range (min/max)19.1-75.6Age range distribution, n (%)< 30 years8 (8.5)30-45 years22 (23.4)45-60 years38 (40.4)60-75 years25 (26.6)> 75 years1 (1.1)Tobacco use, n (%)Non-sm...

Table 1 Dropouts over observation time : Clinical ...

Time periodPatientsImplantsBefore loading58Loading-1 year681-3 years673-5 years13Total1826Table 1 Dropouts over observation time

About this article : Clinical and patient-reported...

Ackermann, KL., Barth, T., Cacaci, C. et al. Clinical and patient-reported outcome of implant restorations with internal conical connection in daily dental practices: prospective observational multicenter trial with up to 7-year follow-up. Int J Implant Dent 6, 14 (2020). https://doi.org/10.1186/s40729-020-00211-z Download citation Received: 16 December 2019 Accepted: 12 Ma...

Rights and permissions : Clinical and patient-repo...

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Clinical and patient-repo...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Clinical and patient-reporte...

A written consent was given by all patients after being informed of the study. The study was performed following the declaration of Helsinki. Ethics committee approval was obtained from the international ethical committee of Freiburg (Germany, Ref. 010/1833). Not applicable. All authors declare that they have no conflicts of interest regarding this study. All authors have been lecturing for Caml...

Author information : Clinical and patient-reported...

Filderstadt, Germany Karl-Ludwig Ackermann Leipzig, Germany Thomas Barth Munich, Germany Claudio Cacaci Landsberg a. L., Germany Steffen Kistler Forchheim, Germany Markus Schlee Department of Maxillofacial Surgery, Goethe University Frankfurt, Frankfurt, Germany Markus Schlee Berlin, Germany Michael Stiller You can also search for this author in PubMed Googl...

Funding : Clinical and patient-reported outcome of...

This study was funded by an unrestricted grant (NISCAM01/10) of the Oral Reconstruction Foundation (previously CAMLOG Foundation).

Acknowledgements : Clinical and patient-reported o...

The authors thank Lucius Keller of Touchpoint Communication AG (Luzern, Switzerland) for the medical writing support.

References : Clinical and patient-reported outcome...

Chang M, Odman PA, Wennstrom JL, Andersson B. Esthetic outcome of implant-supported single-tooth replacements assessed by the patient and by prosthodontists. Int J Prosthodont. 1999;12(4):335–41. Kiltz U, Winter J, Schirmer M, Weber U, Hammel L, Baraliakos X, et al. German translation and cross-cultural adaptation of the ASAS health index: an ICF-based instrument for documentation of functional...

References : Clinical and patient-reported outcome...

Ravald N, Dahlgren S, Teiwik A, Grondahl K. Long-term evaluation of Astra Tech and Branemark implants in patients treated with full-arch bridges. Results after 12-15 years. Clin Oral Implants Res. 2013;24(10):1144–51. Schwarz F, Alcoforado G, Nelson K, Schaer A, Taylor T, Beuer F, et al. Impact of implant-abutment connection, positioning of the machined collar/microgap, and platform switching...

References : Clinical and patient-reported outcome...

Gupta S, Sabharwal R, Nazeer J, Taneja L, Choudhury BK, Sahu S. Platform switching technique and crestal bone loss around the dental implants: a systematic review. Ann Afr Med. 2019;18(1):1–6. Hsu YT, Lin GH, Wang HL. Effects of platform-switching on peri-implant soft and hard tissue outcomes: a systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2017;32(1):e9–e24. Nelson K,...

References : Clinical and patient-reported outcome...

Cacaci C, Ackermann KL, Barth T, Kistler S, Stiller M, Schlee M. A non-interventional multicenter study to document the implants success and survival rates in daily dental practices of the CONELOG screw-line implant. Clin Oral Investig. 2019;23(6):2609–16. Cochran D, Oates T, Morton D, Jones A, Buser D, Peters F. Clinical field trial examining an implant with a sand-blasted, acid-etched surface...

References : Clinical and patient-reported outcome...

Krennmair G, Seemann R, Weinlander M, Piehslinger E. Comparison of ball and telescopic crown attachments in implant-retained mandibular overdentures: a 5-year prospective study. Int J Oral Maxillofac Implants. 2011;26(3):598–606. Slot W, Raghoebar GM, Cune MS, Vissink A, Meijer HJA. Four or six implants in the maxillary posterior region to support an overdenture: 5-year results from a randomize...

Abbreviations : Clinical and patient-reported outc...

Adverse event Bone level change Distance implant shoulder to first visible bone contact Orthopantomogram Plaque index Patient reported outcome measures Platform switching Sulcus bleeding index

Availability of data and materials : Clinical and ...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Clinical and patient-reported outcom...

This prospective observational multicenter study demonstrated successful functional and esthetic outcomes of the study implant restorations (single tooth restoration, fixed partial dentures) with reliable peri-implant hard and soft tissue stability and high patients’ satisfaction. The results are comparable with the outcome of already published controlled randomized clinical studies and retrospe...

Discussion : Clinical and patient-reported outcome...

In recent years, patients’ needs have increased in terms of the esthetic and functional outcome of the dental restoration. PROMs have been reported in several studies and represent a well-described non-invasive method to measure patient’s satisfaction with these needs; however, they might present a lack of standardization [39, 40] due to the very subjective view on esthetics or functionality o...

Discussion : Clinical and patient-reported outcome...

Changes in crestal bone level are well-documented in the literature. Bone remodeling is reported to take place between surgery and loading. The reported changes are generally around 0.5 mm [17, 27, 30] but can reach more than 1 mm [31] in randomized or observational trials. The present study is well in accordance with these findings with its bone remodeling of − 0.52 ± 0.55 mm. Nearly 45%...

Discussion : Clinical and patient-reported outcome...

Endosseous dental implants are a commonly accepted treatment procedure and showed high survival and success rates as well as good functional performance in numerous clinical trials and retrospective analyses, also for Conelog implants as for their specific implant surface [17, 23, 26]. However, in general, one could argue that results of controlled clinical studies do not reflect the real situatio...

Results : Clinical and patient-reported outcome of...

Table 3 shows the mean bone level changes of the implants with available radiographs from insertion to 5-year post-loading. Bone remodeling around the implant was noticeable from surgery to loading, presenting a mean value of − 0.52 ± 0.55 mm. From loading to the 5-year follow-up, the mean change in crestal bone remained clinically stable (−0.09 ± 0.43 mm) (Fig. 3). Split into three g...

Results : Clinical and patient-reported outcome of...

The study was started with 94 patients with 130 implants. At the end of the study (5-year post-loading), 76 patients with 104 implants were considered for analysis. Dropouts were distributed over the time of the study as described in Table 1. The majority of dropouts occurred early in the study phase. The reasons for the dropouts were variable as described in Fig. 1. The demographic and clinica...

Methods : Clinical and patient-reported outcome of...

The study data, soft and hard tissue parameters as well as the PROMs were descriptively analyzed using IBM SPSS V25.0 (IBM Corp., Armonk, NY, USA): Categorical variables were shown with frequencies and mean values were used for continuous variables. Survival analysis was performed using Kaplan–Meier method. Time of loading was the study baseline as per protocol, and the statistical unit was the ...

Methods : Clinical and patient-reported outcome of...

Patients were scheduled to follow-ups at 6 months, 1-, 2-, 3-, 4-, and 5-year post-loading for the assessment of the study parameter (Fig. 1). Depending on the investigators’ standard post-operative protocol, follow-up appointments were scheduled slightly differently: One center skipped the control visits at 6 months. Additionally, due to the observational character of the study and the pati...

Methods : Clinical and patient-reported outcome of...

This is an observational multicenter clinical study, approved by the ethics committee of the Freiburg ethics commission international (feci 010/1833). The study was planned and conducted according to the German medical devices law, the Declaration of Helsinki, good clinical practice, and the reporting is aligned with the STROBE statement. A minimum of 90 to 100 patients were planned to be included...

Introduction : Clinical and patient-reported outco...

Features of the chosen implant system for a study may also influence the outcome of the treatment: The degree of the manufacturer’s tolerances of implants with a conical implant-abutment connection heightens the risk of a mispositioning of the abutment, which cannot be corrected by repeated torqueing. Platform switching (PS) implants tend to have a protective effect on hard implant tissue outcom...

Introduction : Clinical and patient-reported outco...

Many randomized controlled clinical trials have been published about dental implants. They have demonstrated long-term success in the rehabilitation of edentulous patients [1, 2] as well as patients with single or multiple teeth replacements [3, 4]. While this type of trials have an indispensable place in establishing a new product or a new operation technique regarding safety and efficacy, the r...

Abstract : Clinical and patient-reported outcome o...

The interpretation of the results of randomized clinical trials is often questioned in relation with daily circumstances in practices. This prospective observational multicenter study was instigated to reflect the need for information in real-life situations with dental implants with internal conical implant-abutment connection (Conelog implant system). The implants were followed up at least 5-yea...

Fig. 5. PROMs over 5 years: improvement of satis...

Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end

Fig. 4. Soft tissue parameters at 5-year post-load...

Fig. 4. Soft tissue parameters at 5-year post-loading. a Plaque index: score 0, no plaque detected; score 1, plaque only recognized by running a probe across the smooth marginal surface of the implant; score 2, plaque seen by the naked eye; score 3, abundance of soft matter. b Sulcus bleeding index: score 0, no bleeding when a periodontal probe was passed along the gingival margin adjacent to th...

Fig. 3. Standardized peri-apical radiographs repre...

Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5-year post-loading (c) Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5...

Fig. 2. Kaplan-Meier cumulative survival rate : Cl...

Fig. 2. Kaplan-Meier cumulative survival rate Fig. 2. Kaplan-Meier cumulative survival rate

Fig. 1. Study flow-chart: assessments and reason f...

Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits

Table 3 Mean crestal bone level changes in mm : Cl...

Bone level changenMeanSDInsertion-loading103− 0.520.55Loading-1-year follow-up93− 0.040.37Loading-3-year follow-up90− 0.040.40Loading-5-year follow-up86− 0.090.43Table 3 Mean crestal bone level changes in mm

Table 2 Demography of study population : Clinical ...

CharacteristicsCategoryTotalTotal patients/implantsn94/130Center 19/17Center 218/26Center 320/26Center 414/16Center 518/26Center 615/19Gender, n (%)Male30 (31.9)Female64 (68.1)Age at surgery, yearsMean ± SD50.4 ± 13.7Range (min/max)19.1-75.6Age range distribution, n (%)< 30 years8 (8.5)30-45 years22 (23.4)45-60 years38 (40.4)60-75 years25 (26.6)> 75 years1 (1.1)Tobacco use, n (%)Non-sm...

Table 1 Dropouts over observation time : Clinical ...

Time periodPatientsImplantsBefore loading58Loading-1 year681-3 years673-5 years13Total1826Table 1 Dropouts over observation time

About this article : Clinical and patient-reported...

Ackermann, KL., Barth, T., Cacaci, C. et al. Clinical and patient-reported outcome of implant restorations with internal conical connection in daily dental practices: prospective observational multicenter trial with up to 7-year follow-up. Int J Implant Dent 6, 14 (2020). https://doi.org/10.1186/s40729-020-00211-z Download citation Received: 16 December 2019 Accepted: 12 Ma...

Rights and permissions : Clinical and patient-repo...

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Clinical and patient-repo...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Clinical and patient-reporte...

A written consent was given by all patients after being informed of the study. The study was performed following the declaration of Helsinki. Ethics committee approval was obtained from the international ethical committee of Freiburg (Germany, Ref. 010/1833). Not applicable. All authors declare that they have no conflicts of interest regarding this study. All authors have been lecturing for Caml...

Author information : Clinical and patient-reported...

Filderstadt, Germany Karl-Ludwig Ackermann Leipzig, Germany Thomas Barth Munich, Germany Claudio Cacaci Landsberg a. L., Germany Steffen Kistler Forchheim, Germany Markus Schlee Department of Maxillofacial Surgery, Goethe University Frankfurt, Frankfurt, Germany Markus Schlee Berlin, Germany Michael Stiller You can also search for this author in PubMed Googl...

Funding : Clinical and patient-reported outcome of...

This study was funded by an unrestricted grant (NISCAM01/10) of the Oral Reconstruction Foundation (previously CAMLOG Foundation).

Acknowledgements : Clinical and patient-reported o...

The authors thank Lucius Keller of Touchpoint Communication AG (Luzern, Switzerland) for the medical writing support.

References : Clinical and patient-reported outcome...

Chang M, Odman PA, Wennstrom JL, Andersson B. Esthetic outcome of implant-supported single-tooth replacements assessed by the patient and by prosthodontists. Int J Prosthodont. 1999;12(4):335–41. Kiltz U, Winter J, Schirmer M, Weber U, Hammel L, Baraliakos X, et al. German translation and cross-cultural adaptation of the ASAS health index: an ICF-based instrument for documentation of functional...

References : Clinical and patient-reported outcome...

Ravald N, Dahlgren S, Teiwik A, Grondahl K. Long-term evaluation of Astra Tech and Branemark implants in patients treated with full-arch bridges. Results after 12-15 years. Clin Oral Implants Res. 2013;24(10):1144–51. Schwarz F, Alcoforado G, Nelson K, Schaer A, Taylor T, Beuer F, et al. Impact of implant-abutment connection, positioning of the machined collar/microgap, and platform switching...

References : Clinical and patient-reported outcome...

Gupta S, Sabharwal R, Nazeer J, Taneja L, Choudhury BK, Sahu S. Platform switching technique and crestal bone loss around the dental implants: a systematic review. Ann Afr Med. 2019;18(1):1–6. Hsu YT, Lin GH, Wang HL. Effects of platform-switching on peri-implant soft and hard tissue outcomes: a systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2017;32(1):e9–e24. Nelson K,...

References : Clinical and patient-reported outcome...

Cacaci C, Ackermann KL, Barth T, Kistler S, Stiller M, Schlee M. A non-interventional multicenter study to document the implants success and survival rates in daily dental practices of the CONELOG screw-line implant. Clin Oral Investig. 2019;23(6):2609–16. Cochran D, Oates T, Morton D, Jones A, Buser D, Peters F. Clinical field trial examining an implant with a sand-blasted, acid-etched surface...

References : Clinical and patient-reported outcome...

Krennmair G, Seemann R, Weinlander M, Piehslinger E. Comparison of ball and telescopic crown attachments in implant-retained mandibular overdentures: a 5-year prospective study. Int J Oral Maxillofac Implants. 2011;26(3):598–606. Slot W, Raghoebar GM, Cune MS, Vissink A, Meijer HJA. Four or six implants in the maxillary posterior region to support an overdenture: 5-year results from a randomize...

Abbreviations : Clinical and patient-reported outc...

Adverse event Bone level change Distance implant shoulder to first visible bone contact Orthopantomogram Plaque index Patient reported outcome measures Platform switching Sulcus bleeding index

Availability of data and materials : Clinical and ...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Clinical and patient-reported outcom...

This prospective observational multicenter study demonstrated successful functional and esthetic outcomes of the study implant restorations (single tooth restoration, fixed partial dentures) with reliable peri-implant hard and soft tissue stability and high patients’ satisfaction. The results are comparable with the outcome of already published controlled randomized clinical studies and retrospe...

Discussion : Clinical and patient-reported outcome...

In recent years, patients’ needs have increased in terms of the esthetic and functional outcome of the dental restoration. PROMs have been reported in several studies and represent a well-described non-invasive method to measure patient’s satisfaction with these needs; however, they might present a lack of standardization [39, 40] due to the very subjective view on esthetics or functionality o...

Discussion : Clinical and patient-reported outcome...

Changes in crestal bone level are well-documented in the literature. Bone remodeling is reported to take place between surgery and loading. The reported changes are generally around 0.5 mm [17, 27, 30] but can reach more than 1 mm [31] in randomized or observational trials. The present study is well in accordance with these findings with its bone remodeling of − 0.52 ± 0.55 mm. Nearly 45%...

Discussion : Clinical and patient-reported outcome...

Endosseous dental implants are a commonly accepted treatment procedure and showed high survival and success rates as well as good functional performance in numerous clinical trials and retrospective analyses, also for Conelog implants as for their specific implant surface [17, 23, 26]. However, in general, one could argue that results of controlled clinical studies do not reflect the real situatio...

Results : Clinical and patient-reported outcome of...

Table 3 shows the mean bone level changes of the implants with available radiographs from insertion to 5-year post-loading. Bone remodeling around the implant was noticeable from surgery to loading, presenting a mean value of − 0.52 ± 0.55 mm. From loading to the 5-year follow-up, the mean change in crestal bone remained clinically stable (−0.09 ± 0.43 mm) (Fig. 3). Split into three g...

Results : Clinical and patient-reported outcome of...

The study was started with 94 patients with 130 implants. At the end of the study (5-year post-loading), 76 patients with 104 implants were considered for analysis. Dropouts were distributed over the time of the study as described in Table 1. The majority of dropouts occurred early in the study phase. The reasons for the dropouts were variable as described in Fig. 1. The demographic and clinica...

Methods : Clinical and patient-reported outcome of...

The study data, soft and hard tissue parameters as well as the PROMs were descriptively analyzed using IBM SPSS V25.0 (IBM Corp., Armonk, NY, USA): Categorical variables were shown with frequencies and mean values were used for continuous variables. Survival analysis was performed using Kaplan–Meier method. Time of loading was the study baseline as per protocol, and the statistical unit was the ...

Methods : Clinical and patient-reported outcome of...

Patients were scheduled to follow-ups at 6 months, 1-, 2-, 3-, 4-, and 5-year post-loading for the assessment of the study parameter (Fig. 1). Depending on the investigators’ standard post-operative protocol, follow-up appointments were scheduled slightly differently: One center skipped the control visits at 6 months. Additionally, due to the observational character of the study and the pati...

Methods : Clinical and patient-reported outcome of...

This is an observational multicenter clinical study, approved by the ethics committee of the Freiburg ethics commission international (feci 010/1833). The study was planned and conducted according to the German medical devices law, the Declaration of Helsinki, good clinical practice, and the reporting is aligned with the STROBE statement. A minimum of 90 to 100 patients were planned to be included...

Introduction : Clinical and patient-reported outco...

Features of the chosen implant system for a study may also influence the outcome of the treatment: The degree of the manufacturer’s tolerances of implants with a conical implant-abutment connection heightens the risk of a mispositioning of the abutment, which cannot be corrected by repeated torqueing. Platform switching (PS) implants tend to have a protective effect on hard implant tissue outcom...

Introduction : Clinical and patient-reported outco...

Many randomized controlled clinical trials have been published about dental implants. They have demonstrated long-term success in the rehabilitation of edentulous patients [1, 2] as well as patients with single or multiple teeth replacements [3, 4]. While this type of trials have an indispensable place in establishing a new product or a new operation technique regarding safety and efficacy, the r...

Abstract : Clinical and patient-reported outcome o...

The interpretation of the results of randomized clinical trials is often questioned in relation with daily circumstances in practices. This prospective observational multicenter study was instigated to reflect the need for information in real-life situations with dental implants with internal conical implant-abutment connection (Conelog implant system). The implants were followed up at least 5-yea...

Fig. 4. PPS mean crestal bone level change plotted...

Fig. 4. PPS mean crestal bone level change plotted against time (mean, 95 % CI) Fig. 4. PPS mean crestal bone level change plotted against time (mean, 95 % CI)

Fig. 3. Participant flow diagram : A randomized, 1...

Fig. 3. Participant flow diagram Fig. 3. Participant flow diagram

Fig. 2. Restorative flow diagram : A randomized, 1...

Fig. 2. Restorative flow diagram Fig. 2. Restorative flow diagram

Fig. 1. Clinical pictures in each procedure. a Bef...

Fig. 1. Clinical pictures in each procedure. a Before implant placement. b After abutment connection. c Temporary prosthesis. d Final prosthesis Fig. 1. Clinical pictures in each procedure. a Before implant placement. b After abutment connection. c Temporary prosthesis. d Final prosthesis

Table 5 Patient satisfaction at 6 and 12 months, ...

  Indicator Prosthetic comforta Appearanceb Ability to chewc Ability to tasted Fittinge General satisfactionf Treatment arm ...

Table 4 Mean crestal bone level changes, in early ...

Treatment arm Summary statistics Baseline 6 months Change from baseline to 6 months ...

Table 3 Patient demographics and other baseline ch...

Characteristics Early loading arm Conventional loading arm Total (N = 38) (N =...

Table 2 Loading criteria applied at implant placem...

Loading criteria 1 Loading criteria 2 • Sufficient oral hygiene • At least 1 mm bone volume around the implanta • No major dehiscence (

Table 1 Inclusion criteria and exclusion criteria ...

Inclusion criteria Age over 20 Patient who have missing teeth in premolar or molar site Good oral hygiene Predicted implant site has 1–3 quality of bone densityand enough quantity of bone Extraction socket in predicted implant site is completely healed (16 weeks or more) ...

About this article : A randomized, 12-month contro...

Dard, M., Shiota, M., Sanda, M. et al. A randomized, 12-month controlled trial to evaluate non-inferiority of early compared to conventional loading of modSLA implants in single tooth gaps. Int J Implant Dent 2, 10 (2016). https://doi.org/10.1186/s40729-016-0040-8 Download citation Received: 25 September 2015 Accepted: 23 March 2016 Published: 04 April 2016 DOI: https://d...

Rights and permissions : A randomized, 12-month co...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : A randomized, 12-month co...

Michel Dard, Makoto Shiota, Minoru Sanda, Yasutomo Yajima, Hideshi Sekine, and Shohei Kasugai state that there are no conflicts of interest. MD mainly prepared the manuscript and figures. MS arranged this study, participated in its design and coordination, and helped to draft the manuscript. YY, HS, and SK managed the data collection from each centers of Tokyo Dental College Chiba Hospital (TDCC)...

Author information : A randomized, 12-month contro...

College of Dentistry, New York University, New York, NY, USA Michel Dard Tokyo Medical and Dental University, Tokyo, Japan Makoto Shiota, Minoru Sanda & Shohei Kasugai Suidobashi Hospital, Tokyo Dental College, Tokyo, Japan Yasutomo Yajima School of Dentistry, Ohu University, Fukushima, Japan Hideshi Sekine Department of Oral Implantology and Regenerative Dental Medicine, Tokyo Medical ...

Acknowledgements : A randomized, 12-month controll...

This trial was sponsored by Straumann Japan KK. The authors would like to acknowledge the assistance of Eusaku Watanabe and Nariyuki Maezawa (both Straumann Japan KK) for their contributions to the study.

References : A randomized, 12-month controlled tri...

Download references

References : A randomized, 12-month controlled tri...

Krebs M, Schmenger K, Neumann K, Weigl P, Moser W, Nentwig GH. Long-term evaluation of ANKYLOS® dental implants, part I: 20-year life table analysis of a longitudinal study of more than 12,500 implants. Clin Implant Dent Relat Res. 2013. doi:10.1111/cid.12154. Lops D, Bressan E, Pisoni G, Cea N, Corazza B, Romeo E. Short implants in partially edentulous maxillae and mandibles: a 10 to 20 years ...

References : A randomized, 12-month controlled tri...

Salvi GE, Gallini G, Lang NP. Early loading (2 or 6 weeks) of sandblasted and acid-etched (SLA) ITI implants in the posterior mandible. A 1-year randomised controlled clinical trial. Clin Oral Implants Res. 2004;15:142–9. El-Sheikh AM, Shihabuddin OF, Ghoraba SM. A prospective study of early loaded single implant-retained mandibular overdentures: preliminary one-year results. Int J Dent. 2012. ...

References : A randomized, 12-month controlled tri...

Morton D, Bornstein MM, Wittneben JG, et al. Early loading after 21 days healing of nonsubmerged titanium implants with a chemically modified sandblasted and acid-etched surface: two-year results of a prospective two-center study. Clin Implant Dent Relat Res. 2010;12:9–17. Cochran DL, Jackson JM, Bernard JP, et al. A 5-year prospective multicenter study of early loaded titanium implants with a ...

References : A randomized, 12-month controlled tri...

Bornstein MM, Wittneben JG, Brägger U, Buser D. Early loading at 21 days of non-submerged titanium implants with a chemically modified sandblasted and acid-etched surface: 3-year results of a prospective study in the posterior mandible. J Periodontol. 2010;81:809–18. Ganeles J, Zöllner A, Jackowski J, ten Bruggenkate C, Beagle J, Guerra F. Immediate and early loading of Straumann implants wit...

References : A randomized, 12-month controlled tri...

Bornstein MM, Valderrama P, Jones AA, Wilson TG, Seibl R, Cochran DL. Bone apposition around two different sandblasted and acid-etched titanium implant surfaces: a histomorphometric study in canine mandibles. Clin Oral Implants Res. 2008;19:233–41. Lai HC, Zhuang LF, Zhang ZY, Wieland M, Liu X. Bone apposition around two different sandblasted, large-grit and acid-etched implant surfaces at site...

References : A randomized, 12-month controlled tri...

Esposito M, Grusovin MG, Maghaireh H, Worthington HV. Interventions for replacing missing teeth: different times for loading dental implants. Cochrane Database of Syst Rev. 2013;3:CD003878. Esposito M, Grusovin MG, Willings M, Coulthard P, Worthington HV. The effectiveness of immediate, early, and conventional loading of dental implants: a Cochrane systematic review of randomized controlled clini...

References : A randomized, 12-month controlled tri...

Blanes RJ, Bernard JP, Blanes ZM, Belser UC. A 10-year prospective study of ITI dental implants placed in the posterior region. I: clinical and radiographic results. Clin Oral Implants Res. 2007;18:699–706. Covani U, Chiappe G, Bosco M, Orlando B, Quaranta A, Barone A. A 10-year evaluation of implants placed in fresh extraction sockets: a prospective cohort study. J Periodontol. 2012;83:1226–...

Conclusions : A randomized, 12-month controlled tr...

In conclusion, this study demonstrated that early implant loading was non-inferior to conventional implant loading in terms of crestal bone level change in a Japanese patient population in short follow-up period and single tooth gaps in molar regions. High implant survival and patient satisfaction rates, and a good safety profile, were also achieved.

Discussion : A randomized, 12-month controlled tri...

Early loading of the implants showed a good safety profile, with a similar incidence in AEs between the early and conventional loading groups. The benefits to the patient for the early loading procedure were demonstrated by the patient satisfaction question “What does the patient think about the time taken until occlusal loading was started after implantation surgery?” All patients in the earl...

Discussion : A randomized, 12-month controlled tri...

The implant survival rate of 100 % after 12 months is also in line with the results from previous studies with chemically modified SLA implants in various situations, including 100 % survival in early loading of mandibular overdentures [55], 100 % survival in single-tooth applications in the anterior maxilla [56], 96.8 % with maxillary sinus floor augmentation [57], and 98 and 97 % with imme...

Discussion : A randomized, 12-month controlled tri...

This was a randomized, controlled, multicenter clinical trial to investigate whether the outcomes for chemically modified SLA implants in terms of change in crestal bone level from implant surgery to 6 months were non-inferior with early loading (25 ± 3 days) compared to conventional loading (13 ± 1 weeks). The difference in mean crestal bone level change between the early loading and...

Results : A randomized, 12-month controlled trial ...

In the PPS and FAS, the implant survival rate was 100 % after 12 months. In the PPS, the implant success rate was 100 % at all time points in both the conventional and early loading arms; however, in the FAS, the success rate in the conventional loading arm was 100 % at all time points, while in the early loading arm, success was 100 % at suture removal at 12-month follow-up and 95 % at the ...

Results : A randomized, 12-month controlled trial ...

The study enrolled 84 Japanese patients who had single missing tooth in the molar region. Since four patients were withdrawn due to the exclusion criteria (systemic disease, adjacent teeth with probing pocket depth deeper than 4 mm, mental disorder, and bone deficiency, respectively), 80 patients underwent implant placement. Two further patients were withdrawn before randomization because the ins...

Methods : A randomized, 12-month controlled trial ...

In addition, periodontal examination, in the form of probing depth (PD) and bleeding on probing (BoP), was performed at pre-screening and at the 12-month follow-up. Descriptive summary statistics were computed for all parameters, and quantitative parameters were described using mean, standard deviation, median, quartiles, minimum, and maximum. For qualitative variables, absolute and relative freq...

Methods : A randomized, 12-month controlled trial ...

The primary endpoint was a change of crestal bone level between implant surgery (baseline) and final restoration (6 months), assessed by measuring the distance from the implant shoulder to the first bone-to-implant contact both mesially and distally to the implant. Bone level was measured by a single reader on standardized periapical radiographs taken at baseline (day 0), suture removal (7–14...

Methods : A randomized, 12-month controlled trial ...

When a patient fulfilled all inclusion criteria and had no exclusion criteria, then he/she got implant surgery and checked the condition met first criteria for loading (loading criteria 1 (LC1)) (Table 2). All patients received Ti grade IV Straumann Standard Plus Regular Neck (SP RN) implants, 4.1 mm in diameter and 8, 10, or 12 mm in length, with SLActive® surface (Institut Straumann AG, Bas...

Methods : A randomized, 12-month controlled trial ...

This study was designed as a randomized, controlled, multicenter clinical trial to evaluate non-inferiority of early loading compared to conventional loading of dental implants with a chemically modified SLA surface placed in single tooth gaps, involving three centers in Japan (Tokyo Medical and Dental University (TMDU), Tokyo Dental College Chiba Hospital (TDCC), and Tokyo Dental College Suidobas...

Background : A randomized, 12-month controlled tri...

Early loading protocols have become relatively common procedures in many countries for implant restoration, but the procedure is much less common in Japan. The purpose of this study, therefore, was to investigate whether the chemically modified SLA implant with early loading was non-inferior to conventional loading, based on the amount of crestal bone change between baseline and 6 months after su...

Background : A randomized, 12-month controlled tri...

The use of dental implants to replace missing or compromised teeth has been well documented clinically over many years. High implant survival rates have been demonstrated for over 10 [1–3], 15 [4], and 20 years [5, 6]. Long-term survival rates for single-tooth implants have been shown to be greater than those for tooth-supported restorations, e.g., fixed partial dentures (FPDs) [7, 8]. Good lon...

Abstract : A randomized, 12-month controlled trial...

The aim of the study was to evaluate whether early loading of implants with a chemically modified sandblasted, large-grit, acid-etched (SLA) (SLActive®) surface was non-inferior to conventional loading in terms of change in crestal bone level. This was a randomized, controlled, multicenter study. Patients requiring single-tooth rehabilitation in the posterior maxilla or mandible received implant...

Fig. 3. Peri-implant bone level at baseline, 3 mo...

Fig. 3. Peri-implant bone level at baseline, 3 months post-operative, and 6 months post-operative. a Mesial defect depth. b Mesial defect width. c Distal defect depth. d Distal defect width Fig. 3. Peri-implant bone level at baseline, 3 months post-operative, and 6 months post-operative. a Mesial defect depth. b Mesial defect width. c Distal defect depth. d Distal defect width

Fig. 2. Test group (PRF augmentation) : The effect...

Fig. 2. Test group (PRF augmentation) Fig. 2. Test group (PRF augmentation)

Fig. 1. Control group (no PRF augmentation) : The ...

Fig. 1. Control group (no PRF augmentation) Fig. 1. Control group (no PRF augmentation)

Illustration 11. a–d Post-operative healing proc...

Illustration 11. ive (a), 1 week post-operative (b), 1 month post-operative (c), and 3 months post-operative (d) Illustration 11. a–d Post-operative healing process at 3 days post-operative (a), 1 week post-operative (b), 1 month post-operative (c), and 3 months post-operative (d)

Illustration 10. a–d Second measuring, reentry, ...

Illustration 10. a–d Second measuring, reentry, and insertion of a screwed, full ceramic crown Illustration 10. a–d Second measuring, reentry, and insertion of a screwed, full ceramic crown

Illustration 9. a–c Radiographic control a at ti...

Illustration 9. a–c Radiographic control a at time of implant placement (a), 3 months post-operative (b), and 6 months post-operative (c)

Illustration 8. Fixation of the flap with Seralene...

Illustration 8. Fixation of the flap with Seralene® 6.0 Illustration 8. Fixation of the flap with Seralene® 6.0

Illustration 7. Insertion of PRF membranes in a do...

Illustration 7. Insertion of PRF membranes in a double-layered technique for tissue augmentation Illustration 7. Insertion of PRF membranes in a double-layered technique for tissue augmentation

Illustration 6. PRF membrane made by centrifugatin...

Illustration 6. PRF membrane made by centrifugating and pressing the patient’s blood Illustration 6. PRF membrane made by centrifugating and pressing the patient’s blood

Illustration 5. Implant placed with a split-flap t...

Illustration 5. Implant placed with a split-flap technique Illustration 5. Implant placed with a split-flap technique

Illustration 4. NobelSpeedy Replace® (source: htt...

Illustration 4. NobelSpeedy Replace® (source: https://www.nobelbiocare.com/de/de/home/products-and-solutions/implant-systems/nobelspeedy.html) Illustration 4. NobelSpeedy Replace® (source: https://www.nobelbiocare.com/de/de/home/products-and-solutions/implant-systems/nobelspeedy.html)

Illustration 3. Insertion of the implant : The eff...

Illustration 3. Insertion of the implant Illustration 3. Insertion of the implant

Illustration 2. Crestal incision and preparation o...

Illustration 2. Crestal incision and preparation of a split-flap Illustration 2. Crestal incision and preparation of a split-flap

Illustration 1. Measurement of tissue thickness wi...

Illustration 1. Measurement of tissue thickness with an endodontic micro-opener Illustration 1. Measurement of tissue thickness with an endodontic micro-opener

About this article : The effect of PRF (platelet-r...

Hehn, J., Schwenk, T., Striegel, M. et al. The effect of PRF (platelet-rich fibrin) inserted with a split-flap technique on soft tissue thickening and initial marginal bone loss around implants: results of a randomized, controlled clinical trial. Int J Implant Dent 2, 13 (2016). https://doi.org/10.1186/s40729-016-0044-4 Download citation Received: 30 July 2015 Accepted: 23 ...

Rights and permissions : The effect of PRF (platel...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : The effect of PRF (platel...

Julia Hehn, Thomas Schwenk, Marcus Striegel, and Markus Schlee declare that they have no competing interests. This study was self-supported. JH was responsible for the study design and recruitment of the patients, carried out the implant surgery and follow-up examinations, and drafted the manuscript. TS participated in the surgical treatment and follow-up examinations. MS performed the digital me...

Author information : The effect of PRF (platelet-r...

Periodontology, Edel & Weiß Clinic, Ludwigsplatz 1a, 90403, Nuremberg, Germany Julia Hehn Esthetic Dentistry, Edel & Weiß Clinic, Nuremberg, Germany Thomas Schwenk & Markus Striegel Private Clinic for Periodontology, Forchheim and Department of Maxillofacial Surgery, Goethe University, Frankfurt, Germany Markus Schlee You can also search for this author in PubMed...

Acknowledgements : The effect of PRF (platelet-ric...

The authors thank Dr. Wolfgang Reimers of MedCommTools for performing the statistics.

References : The effect of PRF (platelet-rich fibr...

Abrahamsson I, Berglundh T. Effects of different implant surfaces and designs on marginal bone-level alterations: a review. Clin Oral Implants Res. 2009;20 Suppl 4:207–15. Download references

References : The effect of PRF (platelet-rich fibr...

Dohan DM et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3):e45–50. Choukroun J, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3)...

References : The effect of PRF (platelet-rich fibr...

Cardaropoli G et al. Tissue alterations at implant-supported single-tooth replacements: a 1-year prospective clinical study. Clin Oral Implants Res. 2006;17(2):165–71. Fickl S et al. Dimensional changes of the alveolar ridge contour after different socket preservation techniques. J Clin Periodontol. 2008;35(10):906–13. Vela-Nebot X et al. Benefits of an implant platform modification techniqu...

Abbreviations : The effect of PRF (platelet-rich f...

platelet-derived growth factor platelet-rich fibrin standard deviation transforming growth factor-b

Conclusions : The effect of PRF (platelet-rich fib...

Soft tissue augmentation with PRF using a split-flap technique cannot be recommended to alter thin gingiva types. Future experimental and clinical studies will be necessary to evaluate whether augmentation with PRF is suitable for mucosa thickening.

Discussion : The effect of PRF (platelet-rich fibr...

With respect to marginal bone loss, it could be shown that there were no significant differences when comparing dimension of bone loss between test and control groups. The study of present research data shows, to the best knowledge of the authors, no other RCTs about tissue thickening with PRF and peri-implant bone loss. However, several studies focused on mucosa thickening with tissue grafts and ...

Discussion : The effect of PRF (platelet-rich fibr...

In this study over a period of 6 months, it could be demonstrated that mucosal tissue thickening above implants with PRF led to reduced tissue thickness when performed in a split-flap technique. The initial post-operative dehiscence and the associated complete loss of mucosal and augmented tissue above the implant were observed in all test patients. PRF is supposed to be a good healing aid in v...

Results : The effect of PRF (platelet-rich fibrin)...

The mean marginal bone level alterations are displayed in Fig. 3. Six months after surgery, both groups showed a statistically significant peri-implant bone loss. The mesial resp. distal defect depth was 0.70 mm ± 0.72 SD resp. 0.64 mm ± 0.66 SD at baseline. Six months later, the marginal bone defect increased to 1.47 mm ± 0.65 SD on the mesial side resp. 1.46 mm ± 0.54 ...

Results : The effect of PRF (platelet-rich fibrin)...

At time of surgery, the patients ranged in age from 33 to 79 years (mean age 53.8 years). The first surgeries for implant placement in the test group were carried out as described above. Two layers of a PRF matrix were placed on top of the implant. Though surgical flaps were all sutured completely free of tension, a post-operative dehiscence above the implant could be observed in all test pati...

Methods : The effect of PRF (platelet-rich fibrin)...

Comparison of bone level alterations between test and control groups. Data were expressed as means ± standard deviation. Comparisons were made using the Wilcoxon test, the Mann–Whitney U test, and the multiple comparisons test by Schaich-Hamerle (p = 0.05).

Methods : The effect of PRF (platelet-rich fibrin)...

After the implantation, standardized digital X-rays were taken with parallel technique (baseline) (illustration 9). For each patient, an individual customized digital film holder was fabricated to ensure a reproducible radiographic analysis. Patients were instructed to avoid chewing hard nutrition in the treated area and to use chlorhexidine mouthwash and a soft brush twice a day for the first 2 ...

Methods : The effect of PRF (platelet-rich fibrin)...

Patients aged 18+ who required an implant in the posterior mandible were eligible for this study. Exclusion criteria were the following: general contraindications to implant surgery insufficient oral hygiene and periodontitis patients with a history of severe periodontitis bone augmentation required smokers substance abuse uncontrolled diabetes severe cardiovascular problems treated or u...

Background : The effect of PRF (platelet-rich fibr...

As a consequence, recent research focused on soft tissue augmentation of thin gingiva types prior to or simultaneous to implant insertion. Wiesner et al. published a significant gain of soft tissue by thickening the gingiva with a connective soft tissue graft harvested from the palate [12]. Soft tissues at augmented sites were 1.3 mm thicker than on control sites and had a better pink esthetic sc...

Background : The effect of PRF (platelet-rich fibr...

The initial bone modeling around implants within the first year after insertion presents a challenging topic in current research. Previous studies have shown that this process is characterized by a remodeling of the horizontal and vertical bone dimension with a range of 0.7 to 3 mm within the first year [1]. First attempts to reduce this loss of tissue focused on changes of implant shapes, impla...

Abstract : The effect of PRF (platelet-rich fibrin...

Previous studies have shown that adequate thickness or initial augmentation of soft tissue has a positive effect on the stability of peri-implant bone. This randomized, controlled trial aimed to evaluate the influence of augmenting soft tissue with platelet-rich fibrin (PRF) on crestal bone and soft tissue around implants. After randomization, 31 fully threaded titanium implants were inserted in ...

Fig. 2. PTG observed in radiographs at the 8-year ...

Fig. 2. PTG observed in radiographs at the 8-year follow-up Fig. 2. PTG observed in radiographs at the 8-year follow-up

Fig. 1. Consort flowchart : Porous titanium granul...

Fig. 1. Consort flowchart Fig. 1. Consort flowchart

Table 2 Data at baseline, 12 months and 7 years ...

Patient/implants Radiographic defect height at deepest site (mm) The site with the deepest PPD (mm) PlI BoP ...

Table 1 Characteristics of the subjects at the 7-y...

Characteristic Case (PTG) group (n = 6) Control group (n = 6) Age (year), mean ± SD 67 ± 12.9 range, 45–79 ...

About this article : Porous titanium granules in t...

Andersen, H., Aass, A.M. & Wohlfahrt, J.C. Porous titanium granules in the treatment of peri-implant osseous defects—a 7-year follow-up study. Int J Implant Dent 3, 50 (2017). https://doi.org/10.1186/s40729-017-0106-2 Download citation Received: 03 July 2017 Accepted: 12 October 2017 Published: 04 December 2017 DOI: https://doi.org/10.1186/s40729-017-0106-2

Rights and permissions : Porous titanium granules ...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Porous titanium granules in ...

The present study was approved by the Regional Committee for Medical and Health Research Ethics, South East Norway (REK 2015/90). A writen informed consent was signed by all study participants Dr. Johan Caspar Wohlfahrt has received lecture fees from the producers of the material used in the study and is a previous shareholder in the company (Tigran AB, Malmoe, Sweden). Heidi Andersen and Anne Me...

Author information : Porous titanium granules in t...

Department of Periodontology, Institute of Clinical Dentistry, University of Oslo, Pb. 1109 Blindern, 0317, Oslo, Norway Heidi Andersen, Anne Merete Aass & Johan Caspar Wohlfahrt You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in ...

Acknowledgements : Porous titanium granules in the...

The authors would like to thank Dr. Christine Dæhli Oppedal for her participation in the data collection phase of the study and Dr. Janet M. Østrem for English proof-reading of the manuscript.

References : Porous titanium granules in the treat...

Roccuzzo M, et al. Surgical therapy of peri-implantitis lesions by means of a bovine-derived xenograft: comparative results of a prospective study on two different implant surfaces. J Clin Periodontol. 2011;38(8):738–45. Download references

References : Porous titanium granules in the treat...

Jepsen K, et al. Reconstruction of peri-implant osseous defects: a multicenter randomized trial. J Dent Res. 2016;95(1):58–66. Serino G, Turri A. Outcome of surgical treatment of peri-implantitis: results from a 2-year prospective clinical study in humans. Clin Oral Implants Res. 2011;22(11):1214–20. Faggion CM Jr, Listl S, Tu YK. Assessment of endpoints in studies on peri-implantitis treatm...

References : Porous titanium granules in the treat...

Mombelli A, et al. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol. 1987;2(4):145–51. Lindhe J, Meyle J. Peri-implant diseases: consensus report of the Sixth European Workshop on Periodontology. J Clin Periodontol. 2008;35(8 Suppl):282–5. Zitzmann NU, Berglundh T. Definition and prevalence of peri-implant diseases. J Clin Periodo...

Findings : Porous titanium granules in the treatme...

This long-term follow-up of surgical treatment of peri-implant osseous defects showed unpredictable results. Loss of implants was only recorded in PTG-treated patients.

Findings : Porous titanium granules in the treatme...

The present study used a non-resorbable, alloplastic material (PTG) in intra-osseous defects as a reconstructed material. This technique attempts to fill the osseous defect and not solve the disease. With regard to defect fill, it is very important to keep in mind that a non-resorbable graft material such as PTG will be left unresorbed. In this study, PTG graft particles were easily seen on radiog...

Findings : Porous titanium granules in the treatme...

A strict maintenance program every 3–6 months followed by a high standard of oral hygiene may hold a stable peri-implant condition after peri-implantitis surgery [16]. In the present study, access to perform sufficient plaque control at the treated implants was considered acceptable due to previous corrections of the prostheses. The frequency of supportive periodontal care (SPT) was reported t...

Findings : Porous titanium granules in the treatme...

Few studies report long-term results after treatment of peri-implantitis. In this context, it is important to remember that the only true end point for such therapies will be the loss of implants, but most studies solely report clinical and subclinical parameters which are only surrogate markers for the disease state and true result of the performed therapy [17]. In a meta-analysis by Khoskham et...

Findings : Porous titanium granules in the treatme...

Radiographic findings demonstrated similar values after 7 years as the baseline regarding defect depth height in 6/12 treated implants. Three implants, one in the PTG group and two in the OFD group, had progression of radiographic defect depth height, measured at the deepest site, compared to baseline. Assessing the results after 12 months, five of the implants in the PTG group and five of the ...

Findings : Porous titanium granules in the treatme...

Three different manufactures represented the implants included in the analysis. Seven subjects had Brånemark implants, four subjects had been treated with Astra Tech implants and one subject had a Straumann implant. Eleven subjects had periodontal supportive care performed by their hygienist or general dentist at a frequency of 6 months to once yearly. One subject reported sporadic visits. About...

Findings : Porous titanium granules in the treatme...

For each radiograph, the width of the implant was used for image calibration. The defect height was measured from a well-defined reference point at the most coronal part of the implant body, on radiographs taken at baseline, 12 months and 7 years. The radiographic measurements were performed by one investigator (AMA), blinded to the examination timepoint. The changes in vertical defect depth we...

Findings : Porous titanium granules in the treatme...

After 7 years (7.3 years [6.7–8]), all patients who completed the original study were invited for a re-examination. After a multitude of recall strategies including telephone and letters, 17 subjects responded and were recalled to the university dental clinic between April and November 2015. After signing the written informed consent, medical and dental history were recorded and a clinical exa...

Findings : Porous titanium granules in the treatme...

In 2012, the same group of researchers presented results from a randomized parallel arm case-control clinical study, using porous titanium granules as a bone substitute in the corrective surgical treatment of peri-implant osseous defects. Grafting of the defects with PTG was compared with open flap debridement alone. No clinical differences between groups were found after 12 months, but a better ...

Findings : Porous titanium granules in the treatme...

Peri-implantitis was suggested [1] as an infectious and pathological site-specific disease in surrounding peri-implant tissues. At the 6th European Workshops on Periodontology, consensus was made on the definitions related to the peri-implant diseases, peri-implant mucositis and peri-implantitis, respectively [2]. Peri-implant mucositis describes an established inflammatory lesion in the soft ti...

Abstract : Porous titanium granules in the treatme...

A great number of different treatment protocols for peri-implantitis have been suggested but there is no consensus regarding the most effective intervention. The aim of the present study was to evaluate the long-term clinical and radiographic results from a study on peri-implant osseous defect reconstruction. Patients having participated in a randomized clinical study 7 years earlier were invit...