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Latar Belakang : Ketebalan tulang vestibular mandi...

Saat melakukan segala jenis prosedur bedah, ahli bedah perlu mengetahui kemungkinan variasi dalam konfigurasi anatomi kanalis mandibula dan nervus alveolaris inferior (IAN) [1,2,3] Hal ini terutama terjadi saat melakukan reseksi akar, pencabutan gigi bungsu atau pengambilan cangkok tulang autologus. . Teknik yang berbeda dijelaskan untuk rekonstruksi area tulang yang hilang sebelum atau selama pe...

Fig. 6. Position of the right mental foramen : Ves...

Fig. 6. Position of the right mental foramen

Fig. 5. Position of the left mental foramen : Vest...

Fig. 5. Position of the left mental foramen

Fig. 4. Left (l) and right (r) mandibular bone thi...

Fig. 4. Left (l) and right (r) mandibular bone thickness (bt) in the four age groups (group 1, 0–20 years old; group 2, 21–40 years old; group 3, 41–60 years old; group 4, 61 and older) in men (0) and women [1]

Fig. 3. Left (l) and right (r) mandibular bone thi...

Fig. 3. Left (l) and right (r) mandibular bone thickness in all patients

Fig. 2. Definition of the position of the mental f...

Fig. 2. Definition of the position of the mental foramen

Fig. 1. Measurement of mandibular bone thickness, ...

Fig. 1. Measurement of mandibular bone thickness, defined as the distance between the lateral wall of the mandibular canal and the lateral mandibular compact bone (solid turquoise line)

Table 1 Number of men and women in each age group ...

 Age groupTotal1234SexMale41363930146Female44513538168Total 85877468314Table 1 Number of men and women in each age group (group 1, 0–20 years old; group 2, 21–40 years old; group 3, 41–60 years old; group 4, 61 and older)

About this article : Vestibular bone thickness of ...

Valdec, S., Borm, J.M., Casparis, S. et al. Vestibular bone thickness of the mandible in relation to the mandibular canal—a retrospective CBCT-based study. Int J Implant Dent 5, 37 (2019). https://doi.org/10.1186/s40729-019-0189-z Download citation Received: 04 June 2019 Accepted: 30 September 2019 Published: 15 November 2019 DOI: https://doi.org/10.1186/s40729-019-0189...

Rights and permissions : Vestibular bone thickness...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Vestibular bone thickness...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Silvio Valdec and Jan Borm are equally contributing first authors.

Ethics declarations : Vestibular bone thickness of...

The study was approved by the cantonal ethics committee of the canton of Zurich (KEK 2018-01691). Not applicable. Silvio Valdec, Jan Borm, Stephanie Casparis, Georg Damerau, Michael Locher and Bernd Stadlinger declare that they have no competing interests.

Author information : Vestibular bone thickness of ...

Silvio Valdec and Jan M. Borm contributed equally to this work. Clinic of Cranio-Maxillofacial and Oral Surgery, Centre for Dental Medicine, University of Zurich, Plattenstrasse 11, 8032, Zurich, Switzerland Silvio Valdec, Jan M. Borm, Stephanie Casparis, Georg Damerau, Michael Locher & Bernd Stadlinger You can also search for this author in PubMed Google Scholar...

Funding : Vestibular bone thickness of the mandibl...

This study was conducted without external funding.

Acknowledgements : Vestibular bone thickness of th...

The authors thank Jacquie Klesing, Board-Certified Editor in the Life Sciences (ELS), for editing assistance with the manuscript. Further, we thank Malgorzata Roos for supporting the statistical analysis.

References : Vestibular bone thickness of the mand...

Namano S, Behrend DA, Harcourt JK, Wilson PR. Angular asymmetries of the human face. Int J Prosthodont. 2000;13(1):41–6. Phillips JL, Weller RN, Kulild JC. The mental foramen: 2. Radiographic position in relation to the mandibular second premolar. J Endod. 1992;18(6):271–4. Pyun JH, Lim YJ, Kim MJ, Ahn SJ, Kim J. Position of the mental foramen on panoramic radiographs and its relation to the...

References : Vestibular bone thickness of the mand...

Nucera R, Lo Giudice A, Bellocchio AM, Spinuzza P, Caprioglio A, Perillo L, et al. Bone and cortical bone thickness of mandibular buccal shelf for mini-screw insertion in adults. Angle Orthod. 2017;87(5):745–51. Scomparin L, Soares MQ, Rubira CM, Yaedu RY, Imada TS, Centurion BS, et al. CBCT location of the fusion between the buccal and lingual cortical in the mandibular ramus: importance to sa...

References : Vestibular bone thickness of the mand...

Benninger B, Miller D, Maharathi A, Carter W. Dental implant placement investigation: is the anterior loop of the mental nerve clinically relevant? J Craniomaxillofac Surg. 2011;69(1):182–5. Greenstein G, Tarnow D. The mental foramen and nerve: clinical and anatomical factors related to dental implant placement: a literature review. J Periodontol. 2006;77(12):1933–43. Kuribayashi A, Watanabe...

References : Vestibular bone thickness of the mand...

Ozturk A, Potluri A, Vieira AR. Position and course of the mandibular canal in skulls. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113(4):453–8. Agbaje JO, de Casteele EV, Salem AS, Anumendem D, Lambrichts I, Politis C. Tracking of the inferior alveolar nerve: its implication in surgical planning. Clin Oral Investig. 2017;21(7):2213–20. Zahedi S, Mostafavi M, Lotfirikan N. Anatomic stud...

Abbreviations : Vestibular bone thickness of the m...

Bone thickness Cone-beam computed tomography Digital Imaging and Communications in Medicine Inferior alveolar nerve

Availability of data and materials : Vestibular bo...

The original datasets supporting the findings are available.

Conclusions : Vestibular bone thickness of the man...

The results of this study support the relevance of a preoperative CBCT to allow detailed planning of a surgical intervention that may potentially touch the area of the mandibular canal. This applies to surgical procedures like wisdom tooth removal, root resection, implant placement and bone block harvesting. A CBCT allows the exact determination of the horizontal bone thickness vestibular to the I...

Discussion : Vestibular bone thickness of the mand...

In a study comparing measurements between cadavers and CT images, the distance between the upper edge of the mandibular canal and the alveolar ridge showed possible over- and underestimations. The quantification showed a possible overestimation of up to 1.05 mm and a possible underestimation of up to 1.36 mm [34]. This discrepancy is of relevance in preoperative planning. Intraoperatively, a r...

Discussion : Vestibular bone thickness of the mand...

The IAN is an important anatomical structure whose course affects the preoperative planning of a bone graft or implant insertion in the mandible. Knowledge on the bone thickness between the lateral wall of the mandibular canal and the lateral mandibular compact bone as well as of the position of the mental foramen facilitates decision-making [24]. Furthermore, for many other surgical procedures, t...

Results : Vestibular bone thickness of the mandibl...

The median age of the patients was 40.2 years (range 12.6–84.4 years). Patients were distributed almost evenly across the age groups (see Table 1). Figure 3 clearly shows the median vestibular bone thicknesses (bt) at 2-mm intervals throughout the anterior to posterior course of the canal on both the right (bt2 r to bt66 r) and left (bt2 l to bt66 l) side of the mandible. The maximum di...

Methods : Vestibular bone thickness of the mandibl...

In addition, the position of the mental foramen was determined relative to the roots of the neighbouring teeth. This was assessed by defining regions of interest in the area of the first premolar, second premolar and first molar by extending the respective mesial and distal points of the cement-enamel junction caudally along the tooth axis. The position of the midpoint of the mental foramen was th...

Methods : Vestibular bone thickness of the mandibl...

Three hundred fourteen cone-beam computed tomograms (CBCTs) from 168 (53.5%) females and 146 (46.5%) males from the database of the Department of Cranio-Maxillofacial and Oral Surgery, Center of Dental Medicine, University of Zurich, Switzerland, from the years 2008 to 2013 were analysed. Patients were divided into 4 age groups: group 1 = 0–20 years, group 2 = 21–40 years, group 3...

Background : Vestibular bone thickness of the mand...

The mandibular canal is a bilateral, intraosseous opening through which the IAN runs from the mandibular foramen to the mental foramen. The nerve innervates the teeth, the mucous membranes in the area of the mental foramen and the skin around the chin [14, 15]. Anatomical variations of the mandibular canal, such as bifid canals and an anterior loop of the mental nerve, are common [16, 17] and have...

Background : Vestibular bone thickness of the mand...

When performing any kind of surgical procedure, a surgeon needs to be familiar with the possible variations in the anatomical configurations of both the mandibular canal and inferior alveolar nerve (IAN) [1,2,3]. This is particularly the case when performing root resections, removing wisdom teeth or harvesting autologous bone grafts. Different techniques are described for reconstruction of missin...

Fig. 5. Marginal discrepancy distribution in the o...

Fig. 5. Marginal discrepancy distribution in the open and closed techniques, maxillary mandibular, and anterior and posterior regions

Fig. 4. Normality line of the distribution horizon...

Fig. 4. Normality line of the distribution horizontal measurement data for the intraoral and working casts

Fig. 3. Sample distribution according to arch and ...

Fig. 3. Sample distribution according to arch and position

Fig. 2. Light cure acrylic resin verification jig ...

Fig. 2. Light cure acrylic resin verification jig in the patient’s mouth

Fig. 1. Horizontal measurements between the two im...

Fig. 1. Horizontal measurements between the two impression copings in the patient’s mouth

Table 6 Chi-square test of marginal discrepancies ...

Marginal discrepancyOpen trayClosed trayP valueMaxilla6 (33.3%)6 (33.3%)0.999Mandible2 (9.1%)6 (27.3%)0.240Anterior2 (15.4%)3 (23.1%)0.50Posterior6 (22.2%)9 (33.3%)0.272Table 6 Chi-square test of marginal discrepancies for the impression techniques, by implant position in the arch

Table 5 The horizontal discrepancies according to ...

Horizontal discrepanciesPositionNOpen trayClosed trayP valueMeanMedianS.DMeanMedianS. DMaxillaAnterior90.0690.0400.0550.0470.0200.0500.110Posterior90.0980.0400.0930.1010.0500.0900.136Total180.0840.0400.0750.0750.0350.0700.584MandibleAnterior40.0300.0350.0220.0630.0790.0300.999Posterior180.0500.0300.0590.1020.1090.0450.118Total220.04640.040.0540.0950.1040.0400.152Table 5 The horizontal discrepancie...

Table 4 Impression technique accuracy in the anter...

TechniquesVariablesNumber of impressionsMedianMeanSDP valueOpen trayAnterior130.040.05690.04970.360Posterior270.030.06590.0737Closed trayAnterior130.030.05150.05710.039*Posterior270.040.10260.1013Table 4 Impression technique accuracy in the anterior and posterior regions using the Mann-Whitney U test

Table 3 Open and closed tray technique accuracy in...

TechniquesVariablesNumber of impressionsMedianMeanSDP valueOpen trayMaxilla180.0400.08330.0760.107Mandible220.0300.04640.054Closed trayMaxilla180.0400.07560.0760.419Mandible220.0400.09450.0104Table 3 Open and closed tray technique accuracy in the maxilla and mandible, using the Mann-Whitney U test

Table 2 Open and closed tray techniques accuracy u...

TechniquesNumber of impressionsMedianMeanSDP valueOpen tray400.0400.032300.06630.365Closed tray400.0400.04370.918Table 2 Open and closed tray techniques accuracy using the Wilcoxon signed-rank test

Table 1 The t test for horizontal measurements of ...

Impression techniqueNMeanStd. deviationStd. error meantP valueIntraoralOpen409.3273.3560.5310.2050.838Closed409.1812.9740.470Master castOpen409.3593.3760.5340.1880.851Closed409.2252.9700.470Table 1 The t test for horizontal measurements of the intraoral and master cast in the open and closed tray techniques

About this article : A prospective clinical study ...

Osman, M., Ziada, H., Suliman, A. et al. A prospective clinical study on implant impression accuracy. Int J Implant Dent 5, 38 (2019). https://doi.org/10.1186/s40729-019-0190-6 Download citation Received: 01 April 2019 Accepted: 09 October 2019 Published: 19 November 2019 DOI: https://doi.org/10.1186/s40729-019-0190-6

Rights and permissions : A prospective clinical st...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : A prospective clinical st...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : A prospective clinical study...

The ethical principles were adhered to, and ethical approvals to conduct the study were duly obtained from the Ethical Committee of the Ministry of Health, Khartoum State, Khartoum Teaching Dental Hospital, number: [WK/OS/AETEA/44/1]. All authors read and approved the final manuscript and consent to the publication. Motaz Osman, Hassan Ziada, Ahmed Suliman, and Neamat Abubakr Hassan declare that...

Author information : A prospective clinical study ...

Department of Oral Rehabilitation, Faculty of Dentistry, University of Khartoum, Khartoum, Sudan Motaz Osman Clinical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, NV, USA Hassan Ziada Department of Oral Maxillofacial Surgery, University of Khartoum, Khartoum, Sudan Ahmed Suliman Biomedical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, 1001 Sha...

Funding : A prospective clinical study on implant ...

No funding (not applicable).

Acknowledgements : A prospective clinical study on...

The authors would like to acknowledge the statistical support provided by Dr. Abdlaal Fadol.

References : A prospective clinical study on impla...

Kim S, Nicholls JI, Han CH, Lee KW. Displacement of implant components from impressions to definitive casts. Int J Oral Maxillofac Implants. 2006;21:747–55. Papaspyridakos P, Hirayama H, Chen CJ, Ho CH, Chronopoulos V, Weber HP. Full-arch implant fixed prostheses: a comparative study on the effect of connection type and impression technique on accuracy of fit. Clin Oral Implants Res. 2016;27:10...

References : A prospective clinical study on impla...

Kan JY, Rungcharassaeng K, Bohsali K, Goodacre CJ, Lang BR. Clinical methods for evaluating implant framework fit. J Prosthet Dent. 1999;81:7–13. Rutkunas V, Ignatovic J. A technique to splint and verify the accuracy of implant impression copings with light-polymerizing acrylic resin. J Prosthet Dent. 2014;111:254–6. Vigolo P, Millstein PL. Evaluation of master cast techniques for multiple a...

References : A prospective clinical study on impla...

Khalifa N, Allen PF, Abu-bakr NH, Abdel-Rahman ME. Factors associated with tooth loss and prosthodontic status among Sudanese adults. J Oral Sci. 2012;54:303–12. Oliver RC, Brown LJ. Periodontal diseases and tooth loss. Periodontol 2000. 1993;2:117–27. Hollister MC, Weintraub JA. The association of oral status with systemic health, quality of life, and economic productivity. J Dent Educ. 199...

Availability of data and materials : A prospective...

The authors declare that they have full control on all data and materials of this study.

Conclusion : A prospective clinical study on impla...

Within the limitation of this study, there were no differences in the impression accuracy between the open and closed tray techniques, in partially edentulous jaws with two adjacent implants. Also, there were no differences between the two impression techniques regarding marginal discrepancy. The position of the implant, in the maxilla or mandible, had no effect on the impression accuracy of both ...

Discussion : A prospective clinical study on impla...

One of the limitations of our study is the lack of matching arches and regions. This may have yielded variable data and would have perhaps influenced the outcomes of implant impression accuracy. Also, the exact position of the implant in relation to accuracy have not been considered in this study, and further studies should consider evaluating this. A further limitation is that specialists undert...

Discussion : A prospective clinical study on impla...

Regarding the influence on the accuracy of the implant position within the dental arch, the current study found that the implant position in the dental arch had no influence or impact on impression accuracy, similar to the report by Gallucci et al. [24]. However, and in contrast, Papaspyridakos et al. found that the position in the dental arch influenced accuracy [22]. However, the Papaspyridakos ...

Discussion : A prospective clinical study on impla...

Impression accuracy at the implant level is believed to have a higher degree of accuracy, compared to abutment-level impressions [20]. However, studies reporting on impression accuracy in implant dentistry may vary, and there are several possible explanations for these variations. One reason is the splinting together of copings for pick-up impressions compared to the non-splinting of copings. Seco...

Results : A prospective clinical study on implant ...

Eighty impressions were made for 40 patients, using the open, then the closed impression techniques. There were 18 impressions in the maxillary and 22 in the mandibular arch; of these, 13 were in the anterior and 27 in the posterior region (Fig. 3). A t test indicated no statistically significant difference between the open and closed tray techniques for intraoral horizontal measurements again...

Materials and methods : A prospective clinical stu...

Two examiners were involved in the evaluations, and inter-examiner reliability of 0.932 was obtained. All the data were tabulated and statistically analyzed using IBM SPSS Statistics software version 22. The t test was used to compare intraoral and master cast horizontal distances as well as sub-groups of the open and close impression tray techniques. Where data are not normally distributed, Wilc...

Materials and methods : A prospective clinical stu...

There should be accurate imprints of the implant areas. There should be no voids in the occlusal, buccal, lingual, and interproximal surfaces of the neighboring teeth. There should be a proper reproduction of the implant area. There should be no impression material in the analog-impression coping interfaces. The impression material should not be separated from the custom tray. The transfer co...

Materials and methods : A prospective clinical stu...

The current study was conducted to investigate the accuracy of the open and closed implant impression techniques in partially edentulous patients with two adjacent implants. The ethical principles were adhered to, and ethical approval to conduct the study was duly obtained from the Ministry of Health, State Khartoum, Khartoum University Teaching Hospital, number: [WK/OS/AETEA/44/1]. Patients who ...

Introduction : A prospective clinical study on imp...

Tooth loss reduces the masticatory ability, compromises esthetics, and may consequently diminish social interactions, which could significantly impact on the quality of life of individuals [1,2,3]. Treatment options for teeth loss are continuously evolving, from the removable prosthesis to the increasing preference for fixed choices. Furthermore, the progress in the manufacturing of titanium impla...

Fig. 3. Quantification of type I collagen via ELIS...

Fig. 3. Quantification of type I collagen via ELISA. Data representative of the experiment run in triplicate. Values are expressed as mean (± SD). The asterisk symbol indicates a significant difference between groups (p < 0.05)

Fig. 2. a Cell proliferation in gingival fibroblas...

Fig. 2. a Cell proliferation in gingival fibroblasts at 24 h, 48 h, and 72 h. The line chart represents the means and standard deviations from three separate experiments. b Cell viability assay in gingival fibroblast at 24 h, 48 h, and 72 h. The line chart represents the means and standard deviations from three separate experiments. The values are expressed in means (± SD). The as...

Fig. 1. Scanning electron microscopy and laser int...

Fig. 1. Scanning electron microscopy and laser interferometry. a, d Machined surface. b, e 20-min acid treatment. c, f 60-min acid treatment. Original magnification, × 15,000

About this article : Viability and collagen secret...

de Souza, V.Z., Manfro, R., Joly, J.C. et al. Viability and collagen secretion by fibroblasts on titanium surfaces with different acid-etching protocols. Int J Implant Dent 5, 41 (2019). https://doi.org/10.1186/s40729-019-0192-4 Download citation Received: 09 August 2019 Accepted: 24 October 2019 Published: 21 November 2019 DOI: https://doi.org/10.1186/s40729-019-0192-4

Rights and permissions : Viability and collagen se...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Viability and collagen se...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Viability and collagen secre...

This study was approved by the Research Ethics Committee of the São Leopoldo Mandic Research Institute, Campinas/SP (protocol No. 59866216.6.0000.5374). Not applicable. Vilton Zimmermann de Souza, Rafael Manfro, Júlio César Joly, Carlos Nelson Elias, Daiane Cristina Peruzzo, Marcelo Henrique Napimoga, and Elizabeth Ferreira Martinez state that they have no conflicts of interest.

Author information : Viability and collagen secret...

VZS and EFM interpreted and analyzed the data collected, contributed to the drafting of the paper and revised it critically, and were major contributors in writing the manuscript. RM, JCJ, and CNE contributed to the concept/design of the study and the final manuscript. DCP and MHN critically revised and contributed to the final manuscript. All authors read and approved the final version to be publ...

Author information : Viability and collagen secret...

Division of Implantology, Faculdade São Leopoldo Mandic, Campinas, SP, Brazil Vilton Zimmermann de Souza, Júlio César Joly & Daiane Cristina Peruzzo Division of Implantology, SOEBRÁS, Passo Fundo, RS, Brazil Rafael Manfro Materials Science Department, Instituto Militar de Engenharia, Rio de Janeiro, RJ, Brazil Carlos Nelson Elias Division of Immunology, Faculdade São Leopoldo Mandic,...

Funding : Viability and collagen secretion by fibr...

The funding received for this study was from the researcher himself.

Acknowledgements : Viability and collagen secretio...

The authors wish to thank Mrs. Pollyanna Tombini Montaldi for her excellent technical expertise and assistance.

References : Viability and collagen secretion by f...

Velasco-Ortega E, Alfonso-Rodríguez CA, Monsalve-Guil L, España-López A, Jiménez-Guerra A, Garzón I, Alaminos M, Gil FJ. Relevant aspects in the surface properties in titanium dental implants for the cellular viability. Mater Sci Eng C Mater Biol Appl. 2016;64:1–10. Cao J, Wang T, Pu Y, Tang Z, Meng H. Influence on proliferation and adhesion of human gingival fibroblasts from different tit...

References : Viability and collagen secretion by f...

Martinez EF, Araújo VC. In vitro immunoexpression of extracellular matrix proteins in dental pulpal and gingival human fibroblasts. Int Endod J. 2004;37(11):749–55. Lee HJ, Lee J, Lee JT, Hong JS, Lim BS, Park HJ, Kim YK, Kim TI. Microgrooves on titanium surface affect peri-implant cell adhesion and soft tissue sealing; an in vitro and in vivo study. J Periodontal Implant Sci. ...

References : Viability and collagen secretion by f...

Chai WL, Moharamzadeh K, Brook IM, Van Noort R. A review of histomorphometric analysis techniques for assessing implant-soft tissue interface. Biotech Histochem. 2011;86(4):242–54. Buser D, Weber HP, Donath K, Fiorellini JP, Paquette DW, Williams RC. Soft tissue reactions to non-submerged unloaded titanium implants in beagle dogs. J Periodontol. 1992;63(3):225–35. Schierano G, Ramieri G, Cor...

Availability of data and materials : Viability and...

All data generated or analyzed during this study are included in this published article.

Conclusions : Viability and collagen secretion by ...

Therefore, the results of the present study indicate that the acid treatments used did not compromise cell growth nor collagen synthesis by gingival fibroblasts compared to machined titanium. The cost-benefit of manufacturing prosthetic abutments with treated surfaces should however be considered. In addition, in vitro studies using human keratinocytes and histological studies in vivo should be pe...

Discussion : Viability and collagen secretion by f...

The connective tissue seal around the abutment is crucial for perimplant health. Several efforts have previously been made to optimize abutment surfaces, though without consensus on the ideal surface features. Blasquez et al. [11] have shown in their systematic review that different types of surface modifications for implant abutments may provide benefit to the surrounding connective tissue, which...

Discussion : Viability and collagen secretion by f...

The results showed that, regardless of the treatment used, there was no difference in the values of cell proliferation in the different times of analysis. Similarly, cell viability values did not differ, especially after 24 h and 72 h. Corroborating the results of this study, Baltriukiene et al. [17] used grade 2 titanium disks with different surface treatments and demonstrated that the modifi...

Discussion : Viability and collagen secretion by f...

Implant dentistry has for years focused on studying the interface between the bone and implant, searching for a suitable seal to prevent the advance of perimplant disease. Long-term prognosis of dental implants, however, depends not only on osseointegration, but also on the quality of the seal between the mucosa and the implant abutment [13]. The seal provided by the contact between mucosal tissu...

Results : Viability and collagen secretion by fibr...

The results showed that acid treatment of the titanium surfaces for 20 or 60 min did not affect cell proliferation, either after 24 h (p = 0.484), 48 h (p = 0.698), or 72 h (p = 0.287) (Fig. 2a). For the cell viability test, loss of viability was observed for the machined surface after 48 h of culture compared to the groups submitted to acid treatment for 20 or 60 min, which did not...

Material and methods : Viability and collagen secr...

The experiments were repeated three times, under the same conditions, to ensure accuracy. Quantification of secreted type I collagen by fibroblast cultures on to the different surfaces was evaluated by enzyme-linked immunosorbent assay (ELISA). The supernatant was collected and centrifuged at 336g for 10 min. Type I collagen quantification was carried out using the Human Type I Collagen kit (R&...

Material and methods : Viability and collagen secr...

This study was approved by the Research Ethics Committee of the São Leopoldo Mandic Research Institute, Campinas/SP (protocol No. 59866216.6.0000.5374). Titanium disks were commercially pure, grade 4 (n = 108), measuring 6 mm in diameter by 2 mm in thickness, provided by the company Conexão Sistemas de Próteses (Arujá, São Paulo). For the treatment of titanium disk surfaces, sulfuric, ni...

Introduction : Viability and collagen secretion by...

Consolidation of surface treatments for dental implants and knowledge on the cellular mechanisms of osseointegration has propelled research on the sealing capacity of bone to implant surfaces. Although osseointegration is extremely important for implant success, biological sealing of the perimplantar connective tissue is crucial to maintain success in the long-term because it acts as a first barri...

Abbreviations : Does the manual insertion torque o...

Resonance frequency analysis Implant stability quotient

Availability of data and materials : Does the manu...

The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Does the manual insertion torque of ...

The null hypothesis that finger tightening of transducer devices for RFA analysis may have a negative impact on the accuracy of ISQ measurements was rejected. Different forces applied during transducer tightening by different clinicians had no significant effect on the resulting ISQ values. Manual tightening of smartpeg magnetic devices allows for an objective and reliable determination of ISQ val...

Discussion : Does the manual insertion torque of s...

A great number of studies have summarized that the measurement of implant stability with RFA is reliable, is noninvasive, and can be used at any time after implant insertion and during follow-up [19, 20]. Various parameters have been demonstrated to influence the degree of primary implant stability [21, 22]. These include bone density [23, 24], surgical technique [25], implant insertion torque [26...

Results : Does the manual insertion torque of smar...

In the test group, mesial and buccal ISQ values of 30 implants were recorded by four examiners (S1–S4) after hand tightening the smartpegs. The control group considered mesial and buccal ISQ values of 30 implants with mechanically inserted smartpegs. Only 147 values could be recorded because one transducer broke and thereafter no further values could be obtained for this implant. At torque value...

Material and methods : Does the manual insertion t...

Statistical analysis was performed to evaluate the difference between the test and control group. Variance analysis and continuous variables were determined. Pearson r correlation coefficient was tested to verify the relationship between the two variables (e.g., relationship between torque and ISQ). Statistical significance was set at p > 0.05.

Material and methods : Does the manual insertion t...

Three fresh bovine ribs from the same animal were selected for the current in vitro testing; the bovine ribs were of a similar size to those used by Gecikli et al. [16], thus attempting to imitate human edentulous bone with a similar composition of cortical and cancellous bone. The animal was farmed and sacrificed for food production. The bone was stored airtight, humid, and cool from the time the...

Background : Does the manual insertion torque of s...

While dental implants have become increasingly important in the functional and esthetic rehabilitation of patients, implant failure still does occur. Primary stability at the time of implant placement and the development of osseointegration in the following healing process (secondary stability) are essential parameters for implant success [1]. Primary stability can be considered as the biomechanic...

Abstract : Does the manual insertion torque of sma...

There is disagreement about the optimal torque for tightening smartpegs for resonance frequency analysis (RFA). Subjective finger pressure during hand tightening could affect the reliability of the resulting values. The aim of the current study was therefore to assess whether or not the insertion torque of a smartpeg magnetic device influences the implant stability quotient (ISQ) value during RFA....

Fig. 8. Mean values of crestal bone loss (CBL) bet...

Fig. 8. Mean values of crestal bone loss (CBL) between the two groups during the follow-up period. ANOVA test Fig. 8. Mean values of crestal bone loss (CBL) between the two groups during the follow-up period. ANOVA test

Fig. 7. Changes of CBL (mm) between the two groups...

Fig. 7. Changes of CBL (mm) between the two groups in sites with KKT > 2 and ≤ 2 mm. ANOVA test Fig. 7. Changes of CBL (mm) between the two groups in sites with KKT > 2 and ≤ 2 mm. ANOVA test

Fig. 6. Mean values of gingival recession (REC) be...

Fig. 6. Mean values of gingival recession (REC) between the two groups at the end of follow-up period (3-year). ANOVA test Fig. 6. Mean values of gingival recession (REC) between the two groups at the end of follow-up period (3-year). ANOVA test

Fig. 5. Mean values of probing depth (PD) between ...

Fig. 5. Mean values of probing depth (PD) between the two groups during the follow-up period. ANOVA test P > 0.05 Fig. 5. Mean values of probing depth (PD) between the two groups during the follow-up period. ANOVA test P > 0.05

Fig. 4. Schematic view of radiographic measurement...

Fig. 4. Schematic view of radiographic measurement references Fig. 4. Schematic view of radiographic measurement references

Fig. 3. Implants used in the present study and las...

Fig. 3. Implants used in the present study and laser-microtextured intramucosal surface (original magnification × 800) Fig. 3. Implants used in the present study and laser-microtextured intramucosal surface (original magnification × 800)

Fig. 2. Example of the location of a submerged imp...

Fig. 2. Example of the location of a submerged implant, bone, and adjacent tooth Fig. 2. Example of the location of a submerged implant, bone, and adjacent tooth

Fig. 1. Example of the location of a non-submerged...

Fig. 1. Example of the location of a non-submerged implant, bone, and adjacent tooth Fig. 1. Example of the location of a non-submerged implant, bone, and adjacent tooth

Table 4 Patients’ full-mouth periodontal probing...

 FMPPD (mm)FMPS (%)FMBS (%)Mean (SD)Mean (SD)Mean (SD)Baseline1.6 (0.3)13.7 (2.1)11.4 (1.7)3-year follow-up (T3)1.8 (0.2)15.1 (1.4)12.3 (1.4)Significance0.770.810.39Table 4 Patients’ full-mouth periodontal probing depth (FMPPD), full-mouth plaque score (FMPS), and full-mouth bleeding score (FMBS) recorded during the follow-up period

Table 3 Differences in number of sites with plaque...

 T01-year2-year3-yearNumber of sites with plaque Submerged77912 Nonsubmerged1210811 Significance0.230.310.220.82Number of sites with BOP Submerged210914 Nonsubmerged610411 Significance0.080.750.510.41Table 3 Differences in number of sites with plaque and bleeding on probing (BOP) between the two groups during the follow-up period (Wilcoxon signed-rank tests, P > 0.05)

Table 2 Distribution of each implant in each group...

PositionTotal implantsSubmergedNon-submerged142111552316312171-1244222543126321270--341-1351-13653237211442-2451-1464314722-Table 2 Distribution of each implant in each group

Table 1 Demographic data of patients, implants pos...

No. of patients/age (years)/sexPositionSubmergedNonsubmergedLength/diameter (mm)1/44y/M14X 10.5 × 3.826 X9 × 3.82/51y/M36X 9 × 4.644 X9 × 3.83/59y/F35 X10.5 × 3.846X 10.5 × 4.64/38y/F47X 9 × 4.636 X9 × 4.65/57y/M24 X12 × 3.815X 12 × 3.86/44y/F16 X9 × 4.624X 12 × 3.87/60y/M36X 10.5 × 4.646 X10.5 × 4.68/49y/F15 X12 × 3.824X 10.5 × 3.89/46y/M37X 9 × 4.645 X9 × 3.81...

About this article : Clinical and radiographics re...

Guarnieri, R., Di Nardo, D., Di Giorgio, G. et al. Clinical and radiographics results at 3 years of RCT with split-mouth design of submerged vs. nonsubmerged single laser-microgrooved implants in posterior areas. Int J Implant Dent 5, 44 (2019). https://doi.org/10.1186/s40729-019-0196-0 Download citation Received: 15 July 2019 Accepted: 15 November 2019 Published: 18 December 2019 DOI: https:...

Rights and permissions : Clinical and radiographic...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Clinical and radiographic...

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Ethics declarations : Clinical and radiographics r...

The study was approved by the Institutional Ethic committee of La Sapienza University, Rome, Italy, (#4597). All patients were informed that two different implants were used and gave their informed consent to the treatment Not applicable. Renzo Guarnieri, Dario Di Nardo, Gianni Di Giorgio, Gabriele Miccoli, and Luca Testarelli state that they have no competing interests.

Author information : Clinical and radiographics re...

Department of Dental and Maxillofacial Sciences, School of Dentistry, University La Sapienza, Rome, Italy Renzo Guarnieri, Dario Di Nardo, Gianni Di Giorgio, Gabriele Miccoli & Luca Testarelli Treviso, Italy Renzo Guarnieri You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google ...

Funding : Clinical and radiographics results at 3 ...

The study was supported by BioHorizons, Birmingham, AL, USA, who provided the materials.

Acknowledgments : Clinical and radiographics resul...

Authors report no conflict of interests. BioHorizons, Birmingham, AL, USA, provided the materials of the study.

References : Clinical and radiographics results at...

Derks J, Håkansson J, Wennström JL, Tomasi C, Larsson M, Berglundh T. Effectiveness of implant therapy analyzed in a Swedish population: early and late implant loss. J Dent Res. 2015;94(3 Suppl):44S–51S. Download references

References : Clinical and radiographics results at...

Al Amri MD. Crestal bone loss around submerged and nonsubmerged dental implants: a systematic review. J Prosthet Dent. 2016;115(5):564–570.e1. Sanz M, Ivanoff CJ, Weingart D, Wiltfang J, Gahlert M, Cordaro L, Ganeles J, Bragger U, Jackowski J, Martin WC, Jung RE, Chen S, Hammerle C. Clinical and radiologic outcomes after submerged and transmucosal implant placement with two-piece implants in th...

References : Clinical and radiographics results at...

Esposito M, Grusovin MG, Chew YS, Coulthard P, Worthington HV. One-stage versus two-stage implant placement. A Cochrane systematic review of randomised controlled clinical trials. Eur J Oral Implantol. 2009; Summer;2(2):91–9. Berglundh T, Lindhe J. Dimension of the periimplant mucosa. Biological width revisited. J Clin Periodontol. 1996;23:971–3. Flores-Guillen J, Álvarez-Novoa C, Barbieri ...

References : Clinical and radiographics results at...

Esposito M, Coulthard P, Thomsen P, Worthington HV. Interventions for replacing missing teeth: different types of dental implants. Cochrane Database Syst Rev. 2005;1:CD003815. Brånemark PI, Breine U, Adell R, Hansson BO, Lindstrom J, Ohlsson A. Intraosseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3(2):81–100. Brånemark PI, Hansson BO, Adell ...

Availability of data and materials : Clinical and ...

The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Clinical and radiographics results a...

After 3 years of loading, no differences were founded in CBL and soft tissue conditions between single submerged two-stage and non-submerged one-stage laser-microgrooved implants.

Discussion : Clinical and radiographics results at...

Few studies evaluated the influence of vertical KTT on CBL at the time of implant placement [28,29,30]. Linkevicius et al. [30] investigated the influence of vertical KTT on CBL around implants placed 2 mm supracrestally (non-submerged/test) and implants placed at bone level (submerged connected with healing abutments/control), after 1 year of loading. In sites with vertical KTT ≤ 2 mm, al...

Discussion : Clinical and radiographics results at...

Data from available literature indicate that if submerged/nonsubmerged techniques do affect CBL, this effect could be associated with the post-operative healing period [9, 23, 24]. In the present study, at the end of the follow-up period (3 years), no significant difference was detected in CBL around submerged and nonsubmerged implants. A possible explanation for this observation could be that s...

Discussion : Clinical and radiographics results at...

CBL mean values recorded around submerged and nonsubmerged implants at different timepoints are the most interesting results of the present randomized clinical trial. Before functional loading, radiographic CBL was significantly greater in submerged implants than that in nonsubmerged implants (0.23 mm ± 0.05 mm vs. 0.09 mm ± 0.07 mm). During the follow-up period, both implants showed sim...

Results : Clinical and radiographics results at 3 ...

At the end of the follow-up period, no patient dropped off the study, and the survival rate was 100% for both groups of implants. At the 3-year follow-up, no statistically significant difference was found between the study groups regarding PI and BOP (P > 0.05). The number of sites with plaque was 12 (15%) for submerged implants and 11 (13.7%) for the nonsubmerged implants, whereas the mean numbe...

Materials and methods : Clinical and radiographics...

A public domain online software (Raosoft, http://www.raosoft.com/samplesize.html) was used to calculate the minimum number necessary for statistical evaluation. Data were analyzed using SPSS software version 13.0 (Chicago, IL, USA). For clinical parameters (PD and REC) and radiographic CBL, data were calculated for each implant and reported as the mean ± SD, at baseline (T0), at 1-year (T1), 2-ye...

Materials and methods : Clinical and radiographics...

The following radiographic measurements were performed: radiographic implant length (IL): distance (in mm) between the implant coronal margin and the implant apex as assessed at the mid portion of the implant residual bone height at the mesial (MI) and distal (DI) aspects of the implant: distance (in mm) between the line linking the coronal implant margin and the first contact of the crestal b...

Materials and methods : Clinical and radiographics...

In the submerged group, second-stage surgeries for the placement of healing abutments were carried out after 4 months in the mandible and 6 months in the maxilla. This procedure was performed by a midcrestal minimal incision, slightly larger than the coronal diameter of the implant. No secondary surgical manipulation of the soft tissue was performed. Once the healing screw was inserted, suturi...

Materials and methods : Clinical and radiographics...

The cases were randomly divided into two groups as two-stage/submerged and one-stage/nonsubmerged. Thus, in each patient, the two implants (submerged and nonsubmerged) were placed randomly in the left and right posterior area of the mandible, or in the left and right posterior area of the maxilla (Tables 1 and 2). For a complete pre-surgical evaluation, an intra-oral rx and a CBCT scan examinat...

Materials and methods : Clinical and radiographics...

This randomized clinical trial included 20 patients, 12 males and 8 females, between the age of 36 and 64 (mean age of 49.7 ± 12.3 years), who were partially edentulous and needed implants for rehabilitation with a single tooth/implant of two non-adjacent sites. Patients were consecutively enrolled between January and July 2014. The study was approved by the Institutional Ethics committee of La...

Introduction : Clinical and radiographics results ...

In the last decades, the replacement of missing teeth with implant-supported restorations has become a predictable treatment with excellent long-term results [1]. It is based on the concept of intimate interfacial contact between the bone and functionally loaded dental implants, defined as “osseointegration” by Brånemark et al. [2, 3] and “functional ankylosis or direct bone apposition to t...

Abstract : Clinical and radiographics results at 3...

To evaluate and compare radiographic crestal bone loss (CBL) and soft tissue parameters around submerged/two-stage and nonsubmerged/one-stage single implants with the same endosseous portion (body design and surface, thread design and distance) and identical intramucosal laser-microgrooved surface, after 3 years of loading. Twenty submerged/two-stage implants and 20 nonsubmerged/one-stage impla...

Fig. 4. Implant placement surgery after 4 months...

Fig. 4. Implant placement surgery after 4 months of healing (a). Immediate loading of the new implants and the explanation of the implant at the left first molar (b). Panoramic radiograph showing the case finished with 12 months of follow-up (c). Clinical image showing the definitive screw-retained prostheses (d) Fig. 4. Implant placement surgery after 4 months of healing (a). Immediate...

Fig. 3. Panoramic radiograph showing excessive mar...

Fig. 3. Panoramic radiograph showing excessive marginal bone loss affecting all the dental implants in the mandible supporting fixed prostheses (a). Clinical image showing the advanced bone destruction around the implants at the incisors and left premolar regions (b). Clinical image showing the preservation of the pre-existing bone upon implant removal with the counter-torque regions (c). Panor...

Fig. 2. The cause of implant removal : Performance...

Fig. 2. The cause of implant removal Fig. 2. The cause of implant removal

Fig. 1. Frequency distribution of the location of ...

Fig. 1. Frequency distribution of the location of the explanted dental implant Fig. 1. Frequency distribution of the location of the explanted dental implant

Table 1 Description of the implants fractured duri...

Patient Location Manufacturer Abutment connection Type of fracture Location of the fracture Category of bone support around the implant (%) Use of trephine bur 1 25 Unknown Internal Complete fracture Implant body (apical third) 76–100 No 14 Unknown Internal Complete fracture Implant body (apical third) 76–100 Yes 2 15 Nobel Internal Fissure line...

About this article : Performance of the counter-to...

Anitua, E., Fernandez-de-Retana, S. & Alkhraisat, M.H. Performance of the counter-torque technique in the explantation of nonmobile dental implants. Int J Implant Dent 6, 1 (2020). https://doi.org/10.1186/s40729-019-0197-z Download citation Received: 30 July 2019 Accepted: 22 November 2019 Published: 09 January 2020 DOI: https://doi.org/10.1186/s40729-019-0197-z

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

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Ethics declarations : Performance of the counter-t...

This study was performed following the Helsinki Declaration regarding the investigation with human subjects. Not applicable Eduardo Anitua is the Scientific Director of BTI Biotechnology Institute (Vitoria, Spain). He is the head of the Foundation Eduardo Anitua, Vitoria, Spain. Sofia Fernandez-de-Retana and Mohammad H. Alkhraisat are researchers at BTI Biotechnology Institute (Vitoria, Spain).

Author information : Performance of the counter-to...

Clínica Eduardo Anitua, Vitoria, Spain Eduardo Anitua BTI Biotechnology Institute, Vitoria, Spain Eduardo Anitua, Sofia Fernandez-de-Retana & Mohammad H. Alkhraisat Eduardo Anitua Foundation, C/Jose Maria Cagigal 19, 01007, Vitoria, Spain Eduardo Anitua You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can al...

Funding : Performance of the counter-torque techni...

No funding was received for this study.

Acknowledgements : Performance of the counter-torq...

Not applicable

References : Performance of the counter-torque tec...

Howe M-S, Keys W, Richards D. Long-term (10-year) dental implant survival: a systematic review and sensitivity meta-analysis. J Dent. 2019. https://doi.org/10.1016/j.jdent.2019.03.008. Buser D, Sennerby L, De Bruyn H. Modern implant dentistry based on osseointegration: 50 years of progress, current trends and open questions. Periodontol 2000. 2017;73(1):7–21. https://doi.org/10.1111/prd.12185. ...

Availability of data and materials : Performance o...

Data will not be shared but are available upon request.

Conclusions : Performance of the counter-torque te...

The good performance of the counter-torque method, as an atraumatic alternative for nonmobile implant removal, reinforces its use in the clinical practice. However, the technique is not exempt from complications (although at a very low rate).

Discussion : Performance of the counter-torque tec...

To our knowledge, this is the study with the largest sample size reporting the performance, in the clinical practice, of the application of counter-torque technique for the removal of nonmobile dental implants. In this retrospective analysis, the counter-torque method demonstrated to be highly predictable, showing a high success rate. The fracture of the implant (0.65% at the implant apical third)...

Results : Performance of the counter-torque techni...

Table 1 shows the relevant available information regarding the fractured dental implants. Ten dental implant fractures were observed in 7 patients. There were no differences regarding the location of the fractured implants, as 40% were located in the maxilla and 60% were located in posterior areas (Table 1). Postoperative recovery of the patients was uneventful and pain was successfully managed ...

Results : Performance of the counter-torque techni...

In this report, 749 nonmobile dental implants were explanted in 355 patients. Figure 1 shows the anatomical location of the dental implants. The 50.6% of the removed implants were located in the maxilla and 48.2% of the cases were located in the anterior areas. Attending to the causes of explantation, the vast majority of the explantations occurred due to biological complications (86.2%), followe...

Methods : Performance of the counter-torque techni...

Patients of legal age treated for implant explantation of nonmobile dental implants between March 2010 and December 2018 were included in this retrospective study. The treatment was performed using an implant removal kit (BTI Biotechnology Institute, Vitoria, Spain) that allowed the application of a counter-torque to the bone-implant interface [4]. The decision to raise a flap or not was made acc...

Background : Performance of the counter-torque tec...

Although presenting high and acceptable survival rates [1, 2], dental implants fail as a consequence of infection (periimplantitis), excessive biomechanical stress, or improper positioning. Different techniques have been described to remove a failed dental implant that include block resection, buccal bone osteotomy, trephine osteotomy, and piezosurgery [3, 4]. The application of counter-torque to ...

Abstract : Performance of the counter-torque techn...

The application of the counter-torque technique has been proposed as a conservative and atraumatic alternative for the explantation of nonmobile dental implants. The objective of this report is to assess the performance of this technique in a large number of patients. Three hundred and fifty-five patients were treated for the explantation of 749 nonmobile dental implants. The explantations were p...

Figure 6. Control group. Some implant thread areas...

Figure 6. Control group. Some implant thread areas were not covered by bone layer (magnification × 25—toluidine blue) Figure 6. Control group. Some implant thread areas were not covered by bone layer (magnification × 25—toluidine blue)

Figure 5. Control group. Implants belonging to the...

Figure 5. Control group. Implants belonging to the control group showed some small surface areas not contacted with bone (magnification × 25—toluidine blue) Figure 5. Control group. Implants belonging to the control group showed some small surface areas not contacted with bone (magnification × 25—toluidine blue)

Figure 4. Control group. No bone condensation was ...

Figure 4. Control group. No bone condensation was possible with traditional burs and standard implant (magnification × 25—toluidine blue) Figure 4. Control group. No bone condensation was possible with traditional burs and standard implant (magnification × 25—toluidine blue)

Figure 3. Test group. The present histological pho...

Figure 3. Test group. The present histological photo showed a continuous thin layer of newly formed bone along the neck area of the implant (magnification × 25—toluidine blue) Figure 3. Test group. The present histological photo showed a continuous thin layer of newly formed bone along the neck area of the implant (magnification × 25—toluidine blue)

Figure 2. Test group. Implants in the test group s...

Figure 2. Test group. Implants in the test group showed an extremely high percentage of bone directly contacted to implant surface (magnification × 25—toluidine blue) Figure 2. Test group. Implants in the test group showed an extremely high percentage of bone directly contacted to implant surface (magnification × 25—toluidine blue)

Figure 1. Test group. The implant achieved a high ...

Figure 1. Test group. The implant achieved a high osseointegration degree. The newly formed bone appeared well interconnected with the pre-existing trabeculae. The “corticalization” phenomenon is evident: the bone appears densified around a titanium implant (magnification × 8—toluidine blue) Figure 1. Test group. The implant achieved a high osseointegration degree. The newly formed b...

Table 3 Statistical comparison (T test) of examine...

BIC%P < 0.05BV%P < 0.05VamP < 0.05Reverse torqueP > 0.05 NsISQP < 0.05Table 3 Statistical comparison (T test) of examined parameters between the test and control groups. The histomorphometric analysis demonstrated significant differences in BIC% and %BV values between the two implant groups

Table 2 Mean values of histomorphometric parameter...

Implant typeBIC%BV%Vam (μm) ± SDReverse torque (N/cm) ± SDISQ value ± SDTest group70.91 ± 7.9541.83 ± 6.3082.6 ± 23.2798.2 ± 16.8163.5 ± 1.30Control group49.33 ± 10.7329.61 ± 5.0560.5 ± 16.5898.8 ± 24.4059.4 ± 1.39Table 2 Mean values of histomorphometric parameters (%BIC and %BV) and biomechanical values (VAM, reverse torque, and ISQ) of each implant group

Table 1 Basal bone volume percentage (basal %BV) w...

Basal %BV 26.17 ± 2.35Test groupControl group 41.83 ± 6.30*29.61 ± 5.05Table 1 Basal bone volume percentage (basal %BV) was compared to %BV around implants after 2 months of healing in both groups. %BV in the test group was significantly higher than basal %BV (P < 0.05)

About this article : Single-drill implant induces ...

Trisi, P., Falco, A. & Berardini, M. Single-drill implant induces bone corticalization during submerged healing: an in vivo pilot study. Int J Implant Dent 6, 2 (2020). https://doi.org/10.1186/s40729-019-0198-y Download citation Received: 30 August 2019 Accepted: 04 December 2019 Published: 15 January 2020 DOI: https://doi.org/10.1186/s40729-019-0198-y

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Single-drill implant indu...

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Ethics declarations : Single-drill implant induces...

The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol with the protocol number 8110. The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol with the protocol number 8110. The authors declare that they have no competing interests.

Author information : Single-drill implant induces ...

Biomaterial Clinical and Histological Research Association, Private Practice, Via Galilei 8, 65122, Pescara, Italy Paolo Trisi, Antonello Falco & Marco Berardini You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar PT contributed to the study design, animal s...

Funding : Single-drill implant induces bone cortic...

No grants were received for the present study.

Acknowledgements : Single-drill implant induces bo...

The authors wish to thank Cortex® Dental Implants (Shlomi, Israel) and NoDrill® (Milano, Italy) for providing the implants used in the present study.

References : Single-drill implant induces bone cor...

Gehrke SA, Bettach R, Aramburú Júnior JS, Prados-Frutos JC, Del Fabbro M, Shibli JA. Peri-Implant Bone Behavior after Single Drill versus Multiple Sequence for Osteotomy Drill. Biomed Res Int. 2018;11:2018. Möhlhenrich SC, Abouridouane M, Heussen N, Hölzle F, Klocke F, Modabber A. Thermal evaluation by infrared measurement of implant site preparation between single and gradual drilling in art...

References : Single-drill implant induces bone cor...

Summers RB. A new concept in maxillary implant surgery: the osteotome technique. Compendium. 1994;15:152–6. Büchter A, Kleinheinz J, Wiesmann HP, et al. Biological and biomechanical evaluation of bone remodelling and implant stability after using an osteotome technique. Clin Oral Implants Res. 2005;16:1–8. Stavropoulos A, Nyengaard JR, Lang NP, et al. Immediate loading of single SLA implant...

References : Single-drill implant induces bone cor...

Albrektsson T, Brånemark PI, Hansson HA, et al. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52(2):155–70. Molly L. Bone density and primary stability in implant therapy. Clin Oral Implants Res. 2006;2:124–35. Chong L, Khocht A, Suzuki JB, et al. Effect of implant design on initial stability of ...

Availability of data and materials : Single-drill ...

All data and materials are available from the corresponding author in Pescara, Italy.

Conclusions : Single-drill implant induces bone co...

The hypothesis was accepted. Compressing implants with single-drill bone preparation demonstrated many clinical and histological advantages with respect with to standard implant drilling procedures and classical implant shape and design in low-density bone type. It is possible to summarize the advantages of this technique as follows: higher bone to implant contact percentage than the control group...

Discussion : Single-drill implant induces bone cor...

The comparison between the basal %BV and %BV in the test group revealed that these innovative implants were able to increase in a significant way the peri-implant bone density with respect to starting host bone density. This increased peri-implant bone density extended from about 0.5–0.7 mm beyond the implant perimeter causing an osseocorticalization around the fixture profile. A recent study [...

Discussion : Single-drill implant induces bone cor...

Results from the present study clearly show that it is possible to insert an implant using a one-step concept for the surgical preparation of the bone bed in cancellous bone. Guazzi et al. [24], comparing the clinical outcome of implants inserted in sites prepared with a simplified protocol consisting of one large single drill versus multiple conventional drilling steps, demonstrated less surgica...

Results : Single-drill implant induces bone cortic...

No implant failure was observed after 2 months of healing. The clinical examination, done immediately after the bone block retrieval, showed no crestal bone resorption. No bone defects around implants, such as fenestration or dehiscence, were detected. The host bone density expressed in bone volume percentage (basal %BV) was 26.17 ± 2.35. This low value of BV% is common in soft bone, according to...

Materials and methods : Single-drill implant induc...

Specimens were immediately fixed in 10% neutral buffered formalin and processed for histologic analysis. After dehydration, samples were infiltrated with a methyl-methacrylate resin from a starting solution 50% ethanol/resin and subsequently 100% resin, with each step lasting 24 h. After polymerization, the blocks were sectioned and then ground down to about 40 μm. Toluidine blue staining was use...

Materials and methods : Single-drill implant induc...

After implant insertion, cover screws were secured and the surgical wounds were closed by a resorbable periosteal-muscular inner suture, followed by an external cutaneous 2-0 silk suture. Each animal underwent systemic antibiotic therapy for 5 days with 8 ml long-acting Clamoxil (Pfizer Limited, Sandwich, USA). After surgery, animals received appropriate veterinary care and were allowed free acce...

Materials and methods : Single-drill implant induc...

The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol, which followed the guidelines established by the European Union Council Directive of February 2013 (R.D.53/2013). Two female sheep, 4–5 years old, were included in the study. Clinical examination determined that all animals were in good general health. Exclu...

Introduction : Single-drill implant induces bone c...

The aim of the present paper is to evaluate a reduced implant site preparation technique to preserve bone bulk and enhance primary stability using a new conical self-tapping implant in cancellous type IV bone. A histologic, histomorphometric, and biomechanical comparative analysis was conducted in low-density bone of the sheep’s iliac crest. The hypothesis to test is if undersized preparation an...

Introduction : Single-drill implant induces bone c...

It is well documented that implant initial bone fixation, known as primary implant stability, represents the pre-requisite to achieve a successful long-term osseointegration [1]. Many studies demonstrated that the implant primary stability is strictly influenced by host bone density [2], fixture geometry [3, 4], and surgical technique used for preparing bone implant bed [5]. Other studies [6, 7] ...

Abstract : Single-drill implant induces bone corti...

The aim of the present paper is to evaluate a simplified implant site preparation technique to preserve bone bulk and enhance osseointegration using a new conical self-tapping implant in cancellous bone. Ten Expander® 3.8 × 10 mm implants (NoDrill®, Milano, Italy) were inserted in the right side (test group) of sheep’s iliac crest using only the pilot drill 1.8 mm in diameter. Ten 3.8 × 10 ...

Fig. 8. Maximum von Mises stress value in implant ...

Fig. 8. Maximum von Mises stress value in implant bodies (MPa) Fig. 8. Maximum von Mises stress value in implant bodies (MPa)

Fig. 7. Von Mises stress distribution in implant b...

Fig. 7. Von Mises stress distribution in implant bodies. (right: buccal side, left: lingual side) Fig. 7. Von Mises stress distribution in implant bodies. (right: buccal side, left: lingual side)

Fig. 6. Largest maximum principle stress value in ...

Fig. 6. Largest maximum principle stress value in cortical bone (MPa) Fig. 6. Largest maximum principle stress value in cortical bone (MPa)

Fig. 5. Distribution of the maximum principle stre...

Fig. 5. Distribution of the maximum principle stress in the surrounding bone (occlusal view) Fig. 5. Distribution of the maximum principle stress in the surrounding bone (occlusal view)

Fig. 4. Distribution of the maximum principle stre...

Fig. 4. Distribution of the maximum principle stress in the surrounding bone (right: buccal side, left: lingual side) Fig. 4. Distribution of the maximum principle stress in the surrounding bone (right: buccal side, left: lingual side)

Fig. 3. Assembly of implant and bone models. A sta...

Fig. 3. Assembly of implant and bone models. A static load of 100 N was applied obliquely from the buccal side to the occlusal plane of the superstructure at 30 to the long axis of the implant Fig. 3. Assembly of implant and bone models. A static load of 100 N was applied obliquely from the buccal side to the occlusal plane of the superstructure at 30 to the long axis of the implant

Fig. 2. Models of different implant body lengths :...

Fig. 2. Models of different implant body lengths Fig. 2. Models of different implant body lengths

Fig. 1. Three-dimensional CAD model. (upper: a abu...

Fig. 1. Three-dimensional CAD model. (upper: a abutment screw, b superstructure, c implant body; Lower: bone model) Fig. 1. Three-dimensional CAD model. (upper: a abutment screw, b superstructure, c implant body; Lower: bone model)

Table 1 Mechanical properties of each model compon...

 Young’s modulus (GPa)Poisson’s ratioReferenceAbutment screw (Ti-6Al-4V)1100.33[19]Superstructure (gold alloy)96.60.35[20]Cortical bone130.3[21]Cancellous bone1.370.3[21]Implant body (cpTi)1100.34 Implant body (TiZr)97.30.36 Table 1 Mechanical properties of each model component

About this article : Three-dimensional finite elem...

Araki, H., Nakano, T., Ono, S. et al. Three-dimensional finite element analysis of extra short implants focusing on implant designs and materials. Int J Implant Dent 6, 5 (2020). https://doi.org/10.1186/s40729-019-0202-6 Download citation Received: 20 August 2019 Accepted: 11 December 2019 Published: 29 January 2020 DOI: https://doi.org/10.1186/s40729-019-0202-6

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Not applicable Not applicable The authors declare that they have no competing interests.

Author information : Three-dimensional finite elem...

Department of Fixed Prosthodontics, Osaka University Graduate School of Dentistry, Osaka, 565-0871, Japan Haruka Araki, Tamaki Nakano, Shinji Ono & Hirofumi Yatani You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in Pu...

Funding : Three-dimensional finite element analysi...

This research was supported by Grants-in-Aid for Scientific Research T15K204780 and T15K111560 from the Japan Society for the Promotion of Science.

Acknowledgements : Three-dimensional finite elemen...

Not applicable

References : Three-dimensional finite element anal...

Download references

References : Three-dimensional finite element anal...

Gottlow J, Dard M, Kjellson F, Obrecht M, Sennerby L. Evaluation of a new titanium-zirconium dental implant: a biomechanical and histological comparative study in the mini pig. Clin Implant Dent Relat Res. 2012;14:538–45. Jimbo R, Naito Y, Galli S, Berner S, Dard M, Wennerberg A. Biomechanical and histomorphometrical evaluation of TiZr alloy implants: an in vivo study in the rabbit. Clin Implan...

References : Three-dimensional finite element anal...

Yamanishi Y, Yamaguchi S, Imazato S, Nakano T, Yatani H. Influences of implant neck design and implant–abutment joint type on peri-implant bone stress and abutment micromovement: three-dimensional finite element analysis. Dent Mater. 2012;28:1126–33. Harel N, Eshkol-Yogev I, Piek D, Livne S, Lavi D, Ormianer Z. Bone microstrain values of 1-piece and 2-piece implants subjected to mechanical lo...

References : Three-dimensional finite element anal...

Lee TJ, Ueno T, Nomura N, Wakabayashi N, Hanawa T. Titanium-zirconium binary alloy as dental implant material: analysis of the influence of compositional change on mechanical properties and in vitro biologic response. Int J Oral Maxillofac Implants. 2015;31:547–54. Al-Nawas B, Brägger U, Meijer HJA, Naert I, Persson R, Perucchi A. A double-blind randomized controlled trial (RCT) of titanium-13...

References : Three-dimensional finite element anal...

Renouard F, Nisand D. Impact of implant length and diameter on survival rates. Clin Oral Implants Res. 2006;17(Suppl 2):35–51. Lee SA, Lee CT, Fu MM, Elmisalati W, Chuang SK. Systematic review and meta-analysis of randomized controlled trials for the management of limited vertical height in the posterior region: short implants (5 to 8 mm) vs longer implants (> 8 mm) in vertically augmented site...

Availability of data and materials : Three-dimensi...

Not applicable

Conclusion : Three-dimensional finite element anal...

Within the limitations of this study, the following conclusions were drawn. The stress distribution in the cortical bone and implant body was smaller in the TL implant than in the BL implant. The TiZr alloy had a lower elastic modulus than cpTi, and the stress distribution generated in the cortical bone and implant body was also lower. The stress distribution generated in the cortical bone an...

Discussion : Three-dimensional finite element anal...

Clinically, it is generally considered that the crown length increases proportionally when the length of the implant body decreases because of alveolar bone resorption. However, most previous studies performing FEA of short implants have analyzed them with a standard crown length [38]. In this study, the distance from the tip of the implant body to the occlusal plane was standardized to make the a...

Discussion : Three-dimensional finite element anal...

The difference in the implant body structure between the submerged and non-submerged implants greatly affected the stress distribution. Since the TL implant body lies above the bone level rather than level with the crestal bone, it was found that the stress concentrates above the apex of the alveolar bone, regardless of the material type. As a result, the maximum stress value in the cortical bone ...

Discussion : Three-dimensional finite element anal...

Overloading, which is one of the factors contributing to bone resorption around an implant body, can lead to complications because force is applied beyond the prosthodontic or biological tolerance [23]. It is believed that when stress of a certain magnitude is applied to the bone, microscopic bone destruction occurs resulting in bone resorption [24, 25]. Because implants do not have buffering mech...

Results : Three-dimensional finite element analysi...

The distribution of the maximum principal stress in the cortical bone concentrated on the neck of the implant body. In the TL implants, tensile stress was concentrated on the buccal side and compressive stress on the lingual side. In the BL implants, tensile stress concentration was observed on the lingual side. The distributions were similar between the cpTi and TiZr implants (Figs. 4 and 5). Th...

Materials and methods : Three-dimensional finite e...

To validate the accuracy of the FEA model, microstrain of the surrounding bone were compared with the results of in vitro experiment measured with strain gauge [22]. In the literature, it was reported that microstrain of 59.3876 ± 24.7185 μe at the neck of implant and 17.3456 ± 12.9147 μe at the apical occurred in a bovine bone under an oblique load of 120 N. Under the same conditi...

Materials and methods : Three-dimensional finite e...

TL and BL three-dimensional computer-aided design (CAD) implant models were created using the CAD function in computer-aided engineering software (SolidWorks 2014, Dassault Systèmes SolidWorks Corporation, MA, USA), and they were created with reference to conical connection implant used clinically. The connection part of superstructure has a tapered 15° conical shape without any special locking ...

Summary : Three-dimensional finite element analysi...

Dental implants are widely used as a treatment option to replace a defective prosthesis. In recent years, treatment using short implants, which are ≤ 8 mm in length, has been increasing in cases with vertical bone resorption [1]. It is thought that this will become more popular as the number of patients who require minimally invasive treatment, such as older patients and those with chronic d...

Abstract : Three-dimensional finite element analys...

When using short implants, fracture of the implant body and bone resorption are a concern because stress concentrates on and around a short implant. The purpose of this research is to investigate the differences in stress distribution between tissue level (TL) and bone level (BL) implant body designs, and between commercially pure titanium (cpTi) and the newer titanium–zirconium (TiZr) alloy in ...

Table 5 Summary of OHIP-14 (N = 44 and respons...

OHIP domainMinimumMaximumMeanSDFunctional limitation072.341.70Physical pain071.161.51Psychological discomfort081.642.27Physical disability080.751.77Psychological disability081.182.11Social disability080.611.40Handicap080.701.71Total0648.49.7Table 5 Summary of OHIP-14 (N = 44 and response range 0–8)

Table 4 Correlation analyses : Patient experience ...

Outcome variablesCorrelationsSpearman’s rhoP valueOHRQoLOral health compared0.596

Table 3 Patient-reported outcomes : Patient experi...

QuestionResponseFrequencyOral healthVery good/good81.8%Quality of LifeVery good/good90.9%General healthVery good/good81.8%Pain after hip operationExcessive35.0%Satisfaction hip operationVery85.7%Post op infection in hip siteNo95.3%Visible scar on hipYes48.8%Acceptable scarYes20 of 21aReduced sensibility on hip siteNo86.0%Problem walkingNo92.9%Augmented bone block still presentNo6.8%New augmentatio...

Table 2 Patients’ demographic and lifestyle-rela...

VariableFrequencyN or Mean ± SD%Patients Female2454.5 Male2045.5Age (years)61.16 ± 13.10 Age at operation53.73 ± 13.07 Time from augmentation to completing questionnaire (months)93.55 ± 31.75 Civil status Married3068.2 Single1125.0 Widow(er)36.8Housing Alone1227.3 With another person2352.3 > two persons920.5Education Up to primary711.3 Up to secondary23...

Table 1 Summary of questions : Patient experience ...

CategoryResponseQuestion (1) Perceived health-status  General health“Very good” to “bad”  Oral health“Very good” to “bad”  Overall quality of life“Excellent” to “bad” (2) Lifestyle-related  Smoking“Yes,” “no,” or “sometimes”  Appetite“Good” to “bad” (3) Donor site-related  Pain“Yes” and “no”  Infection“Yes” a...

About this article : Patient experience following ...

Gjerde, C.G., Shanbhag, S., Neppelberg, E. et al. Patient experience following iliac crest-derived alveolar bone grafting and implant placement. Int J Implant Dent 6, 4 (2020). https://doi.org/10.1186/s40729-019-0200-8 Download citation Received: 10 October 2019 Accepted: 11 December 2019 Published: 05 February 2020 DOI: https://doi.org/10.1186/s40729-019-0200-8

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Supplementary information : Patient experience fol...

A self-administered questionnaire.

Additional information : Patient experience follow...

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Ethics declarations : Patient experience following...

The Ethics Committee was contacted in 2015, and no ethical approval was needed since this was then considered a quality control study. Written consent was obtained from all participants. Not applicable. Cecilie G Gjerde, Siddharth Shanbhag, Evelyn Neppelberg, Kamal Mustafa, and Harald Gjengedal declare that they have no competing interests.

Author information : Patient experience following ...

Correspondence to Cecilie G. Gjerde.

Author information : Patient experience following ...

Department of Oral and Maxillofacial Surgery, Institute of Clinical Dentistry, University of Bergen, Årstadveien 19, 5009, Bergen, Norway Cecilie G. Gjerde & Evelyn Neppelberg Centre for Clinical Dental Research, Institute of Clinical Dentistry, University of Bergen, Bergen, Norway Cecilie G. Gjerde, Siddharth Shanbhag & Kamal Mustafa Department of Oral and Maxillofacial Surgery, Head an...

Funding : Patient experience following iliac crest...

This work was partially funded by the Research Council of Norway through the BEHANDLING project (grant no. 273551) and TROND MOHN Foundation, Norway (BFS2018TMT10).

Acknowledgements : Patient experience following il...

The staff and surgeons at the Department of Oral and Maxillofacial Surgery, Head and Neck Clinic, Haukeland University Hospital, Bergen. Randi Aursland, master student, who helped collecting data. The patients included in this study.

References : Patient experience following iliac cr...

Landes CA, Bundgen L, Laudemann K, Ghanaati S, Sader R. Patient satisfaction after prosthetic rehabilitation of bone-grafted alveolar clefts with nonsubmerged ITI Straumann dental implants loaded at three months. Cleft Palate Craniofac J. 2012;49(5):601–8. Reisine S, Freilich M, Ortiz D, Pendrys D, Shafer D, Taxel P. Quality of life improves among post-menopausal women who received bone augment...

References : Patient experience following iliac cr...

Locker D, Allen F. What do measures of ‘oral health-related quality of life’ measure? Community Dent Oral Epidemiol. 2007;35(6):401–11. Sischo L, Broder HL. Oral health-related quality of life: what, why, how, and future implications. J Dent Res. 2011;90(11):1264–70. Slade GD. Assessing change in quality of life using the Oral Health Impact Profile. Community Dent Oral Epidemiol. 1998;26...

References : Patient experience following iliac cr...

Hill NM, Horne JG, Devane PA. Donor site morbidity in the iliac crest bone graft. Aust N Z J Surg. 1999;69(10):726–8. Finkemeier CG. Bone-grafting and bone-graft substitutes. J Bone Joint Surg Am. 2002;84-A(3):454–64. Hernigou P, Desroches A, Queinnec S, Flouzat Lachaniette CH, Poignard A, Allain J, et al. Morbidity of graft harvesting versus bone marrow aspiration in cell regenerative thera...

References : Patient experience following iliac cr...

Schaaf H, Lendeckel S, Howaldt HP, Streckbein P. Donor site morbidity after bone harvesting from the anterior iliac crest. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(1):52–8. Sakkas A, Wilde F, Heufelder M, Winter K, Schramm A. Autogenous bone grafts in oral implantology-is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J I...

Abbreviations : Patient experience following iliac...

Health-related quality of life Oral Health Impact Profile-14 Oral health-related quality of life Patient-reported outcome measures Quality of life

Availability of data and materials : Patient exper...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Patient experience following iliac c...

Favorable OHRQoL and satisfaction were reported after advanced reconstruction with iliac crest-derived grafts and implant treatment in orally compromised patients. However, this treatment requires substantial resources including hospitalization and sick leave.

Discussion : Patient experience following iliac cr...

Patients in our study reported satisfaction with the augmentation and implant installation, and as these patients were orally compromised before the operation, their satisfaction with getting fixed teeth most likely improved their perceived oral health condition. This might also, in part, explain why they reported good OHRQoL. Thus, our findings indicate that a majority of patients tolerate the au...

Discussion : Patient experience following iliac cr...

An important finding in this study is that a majority of patients were very satisfied after iliac crest-derived alveolar bone grafting and implant therapy. Although 90% of the patients in our study had successful bone grafting, only 70.1% reported implant survival together with prosthetic rehabilitation after 1 year. These figures are lower than those reported in previous studies [2, 3, 9]. A rev...

Results : Patient experience following iliac crest...

The correlation analyses performed did not show a significant correlation between the complications at the donor site and implant loss (Table 4). The mean OHIP-14 score (Table 5) was 8.4 ± 9.7 (range 0–56) in 44 patients of whom 35 patients scored 14 or less. Nine patients scored a total sum of 1 [1], i.e. “hardly ever” impact on any single item and “at no time” on the remaining ...

Results : Patient experience following iliac crest...

The final sample consisted of 44 patients that responded and completed the questionnaire, giving a response rate of 74.6%: 24 women and 20 men, mean age of 61.2 years ± 13.1 (range 27–82 years). The mean time from augmentation surgery until completing the questionnaire was 7.8 years ± 2.65 (range 1.9–12 years). Summary of demographic and lifestyle-related data is presented (Tabl...

Methods : Patient experience following iliac crest...

Implants were placed 4–6 months after the grafting procedure. The implant installations were performed by different oral surgeons (not in the hospital) and different implant systems were used. The implants installed into the augmented bone were allowed to heal for an additional 4–6 months before loading. The records of the original 69 patients were examined with regard to (1) grafting sit...

Methods : Patient experience following iliac crest...

This cross-sectional retrospective cohort study was based on records from all patients (n = 69) who underwent advanced alveolar augmentation with autologous iliac bone grafts at the Department of Oral and Maxillofacial Surgery, Haukeland University Hospital, Bergen, Norway, over 10 years (2002–2012). These patients were orally compromised with severe chewing problems as well as speech diff...

Background : Patient experience following iliac cr...

Health-related QoL (HRQoL) is a dynamic concept referring to an individual’s subjective assessment and perspective of current general health condition as well as functional, social, and emotional well-being [23, 24]. Most people regard oral health as important for QoL, and this is mediated through the concept of oral health-related QoL (OHRQoL) [25]. In this regard, OHRQoL is an important PROM i...

Background : Patient experience following iliac cr...

Insufficient alveolar bone volume, as a result of periodontal disease, trauma, congenital anomalies and/or resorption atrophy, often presents a clinical challenge for optimal placement of dental implants for prosthetic rehabilitation. In such cases, augmentation of alveolar bone, with either autologous bone, allogeneic, xenogeneic, or alloplastic biomaterials, is a prerequisite for placing implant...

Abstract : Patient experience following iliac cres...

The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment in orally compromised patients. This cross-sectional retrospective cohort study included 59 patients (29 women and 30 men) with major functional problems, who underwent advanced alveolar augm...

Fig. 2. Intraoral radiograph of an immediately pla...

Fig. 2. Intraoral radiograph of an immediately placed post-extractive dental implant with a full contour zirconia restoration after 1 year (same patient as in Fig. 1) Fig. 2. Intraoral radiograph of an immediately placed post-extractive dental implant with a full contour zirconia restoration after 1 year (same patient as in Fig. 1)

Fig. 1. Pre-operative panoramic radiograph of a fa...

Fig. 1. Pre-operative panoramic radiograph of a failing molar in position 36 Fig. 1. Pre-operative panoramic radiograph of a failing molar in position 36

Table 5 Patient’s satisfaction 12 months (T12)...

  Agreement percentage (n = 11) Presence of shame 0.0 Self-confidence has decreased 0.0 Evades eating with the implant 9.1 The ability to chew has decreased 0.0 Implant influences speech 0.0 Implant influences taste 0.0 Not satisfied with the colour of the crown 0.0 Not satisfied with the form of the crown 0.0 Not satisfied with ...

Table 4 Mean value, standard deviation, and freque...

Bone change (mm)n = 11mean (SD)− 0.17 mm (0.73)> − 2.0 to − 1.51 (9.1)> − 1.5 to − 1.00 (0.0)> − 1.0 to − 0.52 (18.2)> − 0.5 to 0.04 (36.4)> 0.0 to 0.52 (18.2)> 0.5 to 1.02 (18.2)Table 4 Mean value, standard deviation, and frequency distribution (percentages) of marginal bone change between 1 month after restoration placement (T1) and 1 year in ...

Table 3 Mean value, standard deviation, and freque...

Bone level (mm)n = 15Mean (SD)− 0.94 mm (0.54)> − 2.5 to − 2.01 (6.7)> − 2.0 to − 1.52 (13.3)> − 1.5 to − 1.04 (26.7)> − 1.0 to − 0.55 (33.3)> − 0.5 to 0.03 (20.0)Table 3 Mean value, standard deviation, and frequency distribution (percentages) of marginal bone level at 1 month after restoration placement (T1)

Table 2 Frequencies and percentages of plaque inde...

 T1 (n = 15)T12 (n = 11)Plaque indexScore 0, 15 (100%)Score 0, 11 (100%)Calculus indexScore 0, 15 (100%)Score 0, 11 (100%)Gingival indexScore 0, 15 (100%)Score 0, 11 (100%)Bleeding indexScore 0, 15 (100%)Score 0, 10 (91%)Score 1, 1 (9%)Probing depth in mm (sd)2.0 (0.9)1.9 (0.8)Table 2 Frequencies and percentages of plaque index scores (possible score 0–3), calculus index scores (possibl...

Table 1 Baseline characteristics of the study grou...

Mean age in years (sd, minimum-maximum) 57 (6.6, 44–67) Gender (number male/female) 6/9 Reason of failure (severe caries/crown fracture/root fracture) 3/6/6 Implant position (maxilla/mandible) 7/8 Implant position (in between teeth/no tooth distally) 11/4   Table 1 Baseline characteristics of the study group

About this article : Immediate implant placement i...

Meijer, H.J.A., Raghoebar, G.M. Immediate implant placement in molar extraction sites: a 1-year prospective case series pilot study. Int J Implant Dent 6, 3 (2020). https://doi.org/10.1186/s40729-019-0201-7 Download citation Received: 29 October 2019 Accepted: 11 December 2019 Published: 12 February 2020 DOI: https://doi.org/10.1186/s40729-019-0201-7

Rights and permissions : Immediate implant placeme...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Immediate implant placeme...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Immediate implant placement ...

This clinical study was conducted in accordance with the World Medical Association Declaration of Helsinki (version VI, 2002). The Medical Ethical Committee of the University Medical Center Groningen considered this case series study not subject to the Medical Research Involving Human Subjects Act (Number M15.184100). The study was registered at the Netherlands Trial Register (Number NL8117). Afte...

Author information : Immediate implant placement i...

Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, PO Box 30.001, NL-9700 RB, Groningen, The Netherlands Henny J. A. Meijer & Gerry M. Raghoebar Department of Implant Dentistry, University Medical Center Groningen, Groningen, The Netherlands Henny J. A. Meijer You can also search for this author in PubMed Google Scholar You can also search for this author in...

Funding : Immediate implant placement in molar ext...

An unrestricted grant from Nobel Biocare Services AG funded the 1-year clinical study; implant materials were provided (study code: 2015-1365).

Acknowledgements : Immediate implant placement in ...

Not applicable.

References : Immediate implant placement in molar ...

Tallarico M, Xhanari E, Pisano M, Gatti F, Meloni SM. Molar replacement with 7 mm-wide diameter implants: to place the implant immediately or to wait 4 months after socket preservation? 1 year after loading results from a randomised controlled trial. Eur J Oral Implantol. 2017;10:169–78. Checchi V, Felice P, Zucchelli G, Barausse C, Piattelli M, Pistilli R, Grandi G, Esposito M. Wide diameter i...

References : Immediate implant placement in molar ...

Hamouda NI, Mourad SI, El-Kenawy MH, Maria OM. Immediate implant placement into fresh extraction socket in the mandibular molar sites: a preliminary study of a modified insertion technique. Clin Implant Dent Relat Res. 2015;17(Suppl 1):e107–16. https://doi.org/10.1111/cid.12135. Demircan S, Çankaya AB. Is immediate implant placement possible in the maxillary molar area? An anatomical study. Qu...

References : Immediate implant placement in molar ...

Gallucci GO, Hamilton A, Zhou W, Buser D, Chen S. Implant placement and loading protocols in partially edentulous patients: a systematic review. Clin Oral Implants Res. 2018;29(Suppl 16):106–34. https://doi.org/10.1111/clr.13276. Slagter KW, Den Hartog L, Bakker NA, Vissink A, Meijer HJA, Raghoebar GM. Immediate placement of dental implants in the esthetic zone: a systematic review and pooled a...

Availability of data and materials : Immediate imp...

The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.

Conclusion : Immediate implant placement in molar ...

Within the limitations of this study, it has been demonstrated that immediate placement of regular diameter implants in molar post-extraction sites of maxilla and mandible resulted in a high implant failure rate during a 1-year follow-up period.

Discussion : Immediate implant placement in molar ...

In an attempt to incorporate the concept of patient engagement, this study investigated the patients’ satisfaction with the rehabilitated posterior region by assessing specific patient-centred outcomes. This was done by the patients filling out the established questionnaire 1 year after restoration placement [26, 27]. All the questioned outcome measures showed high patient satisfaction which is...

Discussion : Immediate implant placement in molar ...

The mean marginal bone level was 0.94 mm below the neck of the implant at 1 month after restoration placement (T1). The optimal position of the peri-implant bone after a maturation period should be at the same level as the neck of the implant. This means that part of the biological width of the present study, which is acting as a barrier, was in contact with the implant surface roughness and w...

Discussion : Immediate implant placement in molar ...

Immediate placement of regular diameter implants in molar post-extraction sites of the maxilla and mandible resulted in a high implant failure rate during a 1-year follow-up period. The implant survival rate was 73.3% after 1 year in function. The performance of immediate placements in post-extraction sites was also analysed in the Cafiero et al., Atieh et al., Tallarico et al., and Checchi et a...

Results : Immediate implant placement in molar ext...

All 15 consecutive patients eligible to join the study on the basis of the inclusion and exclusion criteria agreed to participate in this study. The patient characteristics are depicted in Table 1. All implant-supported restorations had natural antagonistic teeth. Four of the 15 patients treated had a mobile implant, which had to be removed (in two patients 3 months after crown placement and in...

Materials and methods : Immediate implant placemen...

Radiographs were taken and evaluated 1 month and 12 months after restoration placement using a parallel technique, with an X-ray holder for periapical radiographs. They were analysed using a specially designed computer software to perform linear measurements on digital radiographs. The calibration was carried out in the vertical plane of each radiograph by using the known distance of the implan...

Materials and methods : Immediate implant placemen...

An impression was made at implant level 2 weeks after the second stage of the surgery in order to fabricate a single crown. A definitive full-zirconia crown (yttria-stabilized zirconium oxide) with an angulated screw channel (NobelProcera FCZ Implant Crown, NobelBiocare AB) was manufactured in the determined colour at a centralized milling facility (NobelProcera Service Center, Mahwah, NJ, USA) a...

Materials and methods : Immediate implant placemen...

All patients referred to the Department of Oral and Maxillofacial Surgery (University of Groningen, University Medical Hospital), from January 2016 to July 2017, for single-tooth implant therapy in the maxillary and mandibular posterior region were considered for inclusion. The following inclusion criteria were applied: One failing first or second molar in the maxilla or mandible; Sufficient bon...

Background : Immediate implant placement in molar ...

Implant placement and loading protocols are changing [1]. There is a growing tendency to place single tooth implants immediately after the extraction of a failing tooth, especially in the maxillary aesthetic region, and preferably combined with immediate provisionalization [2,3,4,5,6]. This tendency is related to evolving society factors, including more demanding patients and a wish for direct tre...

Abstract : Immediate implant placement in molar ex...

There is a growing tendency to place single tooth implants immediately after extracting a failing tooth in the posterior region. The aim of this prospective case series pilot study was to evaluate immediate implant placement in molar post-extraction sites during a 1-year follow-up period. Fifteen consecutive patients with a single failing molar in the maxilla or mandible, and presenting enough bo...

Fig. 6. Optic microscope photo (× 9 magnification...

Fig. 6. Optic microscope photo (× 9 magnification) after 30 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant (group A). Right side: laser-treated implant Fig. 6. Optic microscope photo (× 9 magnification) after 30 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant ...

Fig. 5. Optic microscope photo (× 9 magnification...

Fig. 5. Optic microscope photo (× 9 magnification) after 15 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant (group A). Right side: laser-treated implant Fig. 5. Optic microscope photo (× 9 magnification) after 15 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant ...

Fig. 4. Exemplificative photo of implant placement...

Fig. 4. Exemplificative photo of implant placement in sheep iliac crest (left side). All implant groups were inserted in the same bone host Fig. 4. Exemplificative photo of implant placement in sheep iliac crest (left side). All implant groups were inserted in the same bone host

Fig. 3. Scanning electron microscopy picture of gr...

Fig. 3. Scanning electron microscopy picture of group C implant surface Fig. 3. Scanning electron microscopy picture of group C implant surface

Fig. 2. Scanning electron microscopy picture of gr...

Fig. 2. Scanning electron microscopy picture of group B implant surface Fig. 2. Scanning electron microscopy picture of group B implant surface

Fig. 1. Scanning electron microscopy picture of gr...

Fig. 1. Scanning electron microscopy picture of group A implant surface Fig. 1. Scanning electron microscopy picture of group A implant surface

Table 3 Mean BIC% value of each group after 30 d...

Group BIC% (mean ± SD) A 50.31 ± 13.44 B 56.53 ± 13.62 C 20.54 ± 11.06   Table 3 Mean BIC% value of each group after 30 days of healing

Table 2 Mean BIC% value of each group after 15 d...

Group BIC% (mean ± SD) A 39.08 ± 15.85 B 37.35 ± 15.76 C 25.28 ± 8.97   Table 2 Mean BIC% value of each group after 15 days of healing

Table 1 Implants details of both groups: screw pit...

 Group A implantsGroup B implantsGroup C implantsScrew pitch1.25 mm0.6 mm0.6 mmSmooth neck2.8 mm0.25 mm0.25 mmSurface treatmentLarge grit-blasted and acid-etched SLA surface, processed to a high degree of hydrophilicity (SLActive®)Laser surface characterized by a series of 20 μm diameter holes (7–10 μm deep) every 10 μm (Syntegra®)Machined surfaceSurface roughness (Ra)1.5...

About this article : Comparative evaluation among ...

De Tullio, I., Berardini, M., Di Iorio, D. et al. Comparative evaluation among laser-treated, machined, and sandblasted/acid-etched implant surfaces: an in vivo histologic analysis on sheep. Int J Implant Dent 6, 7 (2020). https://doi.org/10.1186/s40729-019-0204-4 Download citation Received: 30 August 2019 Accepted: 24 December 2019 Published: 19 February 2020 DOI: https://doi.org/10.1186/s40...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

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Ethics declarations : Comparative evaluation among...

The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol, according to the guidelines established by the European Union Council Directive of February 2013 (R.D.53/2013) (protocol number 3809). The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the st...

Author information : Comparative evaluation among ...

Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy I. De Tullio, F. Perfetti & G. Perfetti Pescara, Italy M. Berardini Foggia, Italy D. Di Iorio You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You c...

Funding : Comparative evaluation among laser-treat...

No grants were received for the present study.

Acknowledgements : Comparative evaluation among la...

The authors wish to thank the company Geass s.r.l. for providing implants used in the present study.

References : Comparative evaluation among laser-tr...

Piattelli A, Manzon L, Scarano A, Paolantonio M, Piattelli M. Histologic and histomorphometric analysis of the bone response to machined and sandblasted titanium implants: an experimental study in rabbits. Int J Oral Maxillofac Implants. 1998;13:805–10. Lee JT, Cho SA. Biomechanical evaluation of laser-etched Ti implant surfaces vs. chemically modified SLA Ti implant surfaces: Removal torque an...

References : Comparative evaluation among laser-tr...

Gaggl A, Schultes G, Muller WD, Karcher H. Scanning electron microscopical analysis of laser-treated titanium implant surfaces. A comparative study. Biomaterials. 2000;21(10):1067–73. Bonsignore LA, Colbrunn RW, Tatro JM, Messerschmitt PJ, Hernandez CJ, Goldberg VM, Stewart MC, Greenfield EM. Surface contaminants inhibit osseointegration in a novel murine model. Bone. 2011;49(5):923–30. Peng...

References : Comparative evaluation among laser-tr...

Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52(2):155–70. Puleo DA, Nanci A. Understanding and controlling the bone-implant interface. Biomaterials. 1999;20(23-24):2311–21. Huang MS, Chen LK, Ou KL, et al. Rapid osseointegration of titanium...

Availability of data and materials : Comparative e...

All data and materials are available at University Chieti-Pescara, Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.

Conclusions : Comparative evaluation among laser-t...

Results from the present in vivo analysis revealed that both sandblasted and acid-etched titanium implants and laser-treated titanium implants, compared to the machined ones, have higher values of osseointegration in less healing time. Indeed, both groups A and B at 15 days had higher values of the BIC% if compared to group C and were able to significantly increase their BIC% in the passage fro...

Discussion : Comparative evaluation among laser-tr...

Data showed by the present study suggest that laser and sandblasted and acid-etched surface treatments could enhance the osteogenic bone formation by “contact,” already observed by other authors [20, 21]. Another interesting emerging datum is the observation of BIC% changes between 15 and 30 days: it is possible to assume that between the fifteenth and the thirtieth day, most part of the pe...

Discussion : Comparative evaluation among laser-tr...

In the present study, the iliac crest of the sheep was chosen as a model because the site is characterized by a cancellous bone rich in marrow spaces, similar for quality to D4 density. This bone model appears superimposable to postero-lateral sectors of the human upper jaw that often represents a hard challenge for implant osseointegration due to low bone density. Bone quality, in fact, is a key...

Results : Comparative evaluation among laser-treat...

All implants resulted clinically integrated and stable into the bone tissue. No signs of tissue inflammation or infection were detected. At low magnification, all the samples appeared surrounded by new tissue. The distinction between native tissue and newly formed bone was not clear, likely due to the fact that the latter is still in an initial forming phase. In the machined samples (group C) bon...

Materials and methods : Comparative evaluation amo...

Measurement of the total length of the left half of the fixture; Measurement of the contact area between bone and implant in the left half of the fixture; Measurement of the total length of the right half of the fixture; and Measurement of the contact area between bone and implant in the right half of the fixture. Afterwards, the sum of parameters A and C represented the total length of the wh...

Materials and methods : Comparative evaluation amo...

Implant drilling procedures were carried out using the drill sequence recommended by the manufacturer. The drill speed was set at 700 rpm under continuous sterile saline solution irrigation (stored at + 4 °C). Implants were inserted with an insertion torque peak between 28 and 34 Ncm. Each animal received three implants of each group. The suture of deep muscle planes was performed with poly...

Materials and methods : Comparative evaluation amo...

The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol, which followed guidelines established by the European Union Council Directive of February 2013 (R.D.53/2013). A total of 36 implants were used in the present study. Implants had different macro-geometries and surfaces and they were divided into three groups of...

Introduction : Comparative evaluation among laser-...

In addition, some animal studies [15, 16] found an increased removal torque in laser processed implants compared to machined surface implants inserted. The aim of the present paper was to evaluate the osseointegration process, in terms of bone to implant contact percentage (BIC%), of three different implants surface (machined, sandblasted and acid-etched, and laser-treated) both after 15 and 30...

Introduction : Comparative evaluation among laser-...

Dental implant surfaces represent one of the key factors that could influence the osseointegration processes [1]. Puleo et al. [2] confirmed that the surface topography, as well as the chemical nature and the implant macro and micro geometry, is involved in creating a clinical and histological efficient bone-implant interface. It was demonstrated that different superficial treatments could affect ...

Abstract : Comparative evaluation among laser-trea...

The aim of the present in vivo analysis was to evaluate the osseointegration process of titanium implants with three different surfaces (machined, sandblasted and acid-etched, and laser-treated) after 15 and 30 days of healing period. Thirty-six implants with different surfaces were placed in the iliac crest of four Bergamasca sheep. The implant surfaces tested were sandblasted and acid-etched ...

Fig. 4. Micro-CT images indicate maxillary fist mo...

Fig. 4. Micro-CT images indicate maxillary fist molar site will be able to provide a substantial cancellous bone to support a dental implant. a Sagittal plane. b Frontal plane Fig. 4. Micro-CT images indicate maxillary fist molar site will be able to provide a substantial cancellous bone to support a dental implant. a Sagittal plane. b Frontal plane

Fig. 3. a–c Micro-CT frontal planes indicate the...

Fig. 3. a–c Micro-CT frontal planes indicate the location of implant. d, e Micro-CT sagittal plane. f, g Micro-CT transverse plane. h Micro-CT 3D constructed image indicates osseointegration around the implant fixture Fig. 3. a–c Micro-CT frontal planes indicate the location of implant. d, e Micro-CT sagittal plane. f, g Micro-CT transverse plane. h Micro-CT 3D constructed image indicates...

Fig. 2. Implantation of two implants at maxillary ...

Fig. 2. Implantation of two implants at maxillary diastemata per rat. a Surgery implantation. b X-ray periapical picture after surgery. c Seven weeks after implantion Fig. 2. Implantation of two implants at maxillary diastemata per rat. a Surgery implantation. b X-ray periapical picture after surgery. c Seven weeks after implantion

Fig. 1. a) Time course of the experiment. b) Curve...

Fig. 1. a) Time course of the experiment. b) Curve of the rat body weight change. c) Implant survival after 7 weeks of implantation. Implant success and failure rate is analyzed by using Clopper-Pearson’s exact method at 95% confidence interval. Our experiment data indicate that the true success rate of implantation in maxillary natural diastema in rat is less than 38.4% at a confident level o...

Table 1 Rat body weight during the experiment : Is...

None Table 1 Rat body weight during the experiment

About this article : Is maxillary diastema an appr...

Yue, G., Edani, H., Sullivan, A. et al. Is maxillary diastema an appropriate site for implantation in rats?. Int J Implant Dent 6, 8 (2020). https://doi.org/10.1186/s40729-019-0203-5 Download citation Received: 29 August 2019 Accepted: 24 December 2019 Published: 26 February 2020 DOI: https://doi.org/10.1186/s40729-019-0203-5

Rights and permissions : Is maxillary diastema an ...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Is maxillary diastema an ...

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Ethics declarations : Is maxillary diastema an app...

Animals were maintained and experiments were performed according to a protocol that was approved by the Rutgers Institutional Animal Care and Use Committee (IACUC). On behalf of all the authors, corresponding author of the current manuscript hereby declares that the abovementioned manuscript which is submitted for publication is NOT under consideration elsewhere. The authors hereby declare that ...

Author information : Is maxillary diastema an appr...

Correspondence to Mohammad Ali Saghiri.

Author information : Is maxillary diastema an appr...

Department of Periodontics, Rutgers School of Dental Medicine, Newark, NJ, USA Gang Yue, Husham Edani & Andrew Sullivan The Office of Institutional Assessment, Rutgers School of Dental Medicine, Newark, NJ, USA Shuying Jiang Department of Restorative Dentistry, Rutgers School of Dental Medicine, Newark, NJ, 07103, USA Hamed Kazerani & Mohammad Ali Saghiri Department of Endodontics, Univ...

Funding : Is maxillary diastema an appropriate sit...

N/A

Acknowledgements : Is maxillary diastema an approp...

This publication is made possible due to the generosity and support from senior faculties of the Department of Periodontics, RSDM. They are Dr. Howard Drew, vice chairman of Department of Periodontics, Dr. Emil Cappetta, Director of Postgraduate Program, and Dr. Joel Pascuzzi, Director of the Undergraduate Periodontal Program. Particularly, Dr. Michael Conte, Senior Associate Dean for the Office o...

References : Is maxillary diastema an appropriate ...

Inouye KAS, Bisch FC, Elsalanty ME, Zakhary I, Khashaba RM, Borke JL. Effect of metformin on periimplant wound healing in a rat model of type 2 diabetes. Implant Dent. 2014;23:319–27. Lin Z, Rios HF, Volk SL, Sugai JV, Jin Q, Giannobile WV. Gene expression dynamics during bone healing and osseointegration. J Periodontol. 2011;82:1007–17. Scala A, Lang NP, Schweikert MT, de Oliveira JA, Range...

References : Is maxillary diastema an appropriate ...

Gutwald R, Haberstroh J, Stricker A, Rüther E, Otto F, Xavier SP, et al. Influence of rhBMP-2 on bone formation and osseointegration in different implant systems after sinus-floor elevation. An in vivo study on sheep. J Craniomaxillofac Surg. 2010;38:571–9. Assenza B, Scarano A, Perrotti V, Vozza I, Quaranta A, Quaranta M, et al. Peri-implant bone reactions around immediately loaded conical im...

References : Is maxillary diastema an appropriate ...

Casap N, Nimri S, Ziv E, Sela J, Samuni Y. Type 2 diabetes has minimal effect on osseointegration of titanium implants in Psammomys obesus. Clin Oral Implants Res. 2008;19:458–64. Hashiguchi C, Kawamoto S-I, Kasai T, Nishi Y, Nagaoka E. Influence of an antidiabetic drug on biomechanical and histological parameters around implants in type 2 diabetic rats. Implant Dent. 2014;23:264–9. Lioubavi...

References : Is maxillary diastema an appropriate ...

Grand View Research, Dental implants market size, share & trends analysis report by product (titanium implants, zirconium implants), by region (North America, Europe, Asia Pacific, Latin America, MEA), and segment forecasts, 2018 – 2024. 2018. Eke PI, Dye B, Wei L, Thornton-Evans G, Genco R. Prevalence of periodontitis in adults in the United States: 2009 and 2010. J Dent Res. 2012;91:914–20....

Availability of data and materials : Is maxillary ...

N/A

Conclusion : Is maxillary diastema an appropriate ...

According to the results of the present study, the authors have concluded the following outcomes: Current study indicates that maxillary nature diastema could be a site to place implant, but it has a low successful rate. Data indicate that the true success rate of implantation in maxillary natural diastema in rat is less than 38.4% at a confident level of 95%. Therefore, it is not an appropriate ...

Discussion : Is maxillary diastema an appropriate ...

The current investigation followed the protocol depicted in the article by Freire et al. [15] and tried to modify the procedure of induction of peri-implantitis. Freire and coworkers were precoating the implant with bacteria to induce the inflammation. Our design is to induce the peri-implantitis after ossointegration of the implant. However, the implant survival rate is one per 12 of implant or o...

Discussion : Is maxillary diastema an appropriate ...

Upon a comprehensive literature search, there are articles reported to place implants at maxillary first molar area. However, for variant reasons, these models are not clinical comparable. First, animal sizes are too small to have enough bone to support implant, i.e., Koutouzis et al. reported their experiment on rat model [31]. They placed diameter 1.5 mm × 2 mm length implants in approximat...

Discussion : Is maxillary diastema an appropriate ...

To explore the effective treatment for patients with severe systemic diseases and peri-implantitis, animal models are the most crucial subjects to help investigators to reveal the mechanisms underlying these disorders. Murine models both mice and rats are the most commonly used animal models in research because of their lower cost, biological relevance to human being, and available of genetic muta...

Results : Is maxillary diastema an appropriate sit...

Under anesthesia, two implants were placed in maxillary diastemata in each rat (Fig. 2a). After implantation before the animal awakened, an X-ray was taken extraorally with a digital perioapical digital film. The X-ray indicates two implants were successfully placed in maxillary diastemata in one rat (Fig. 2b). When rats arrived at animal facility, animals were stabilized for synchronizing. At da...

Materials and methods : Is maxillary diastema an a...

Baseline of osseointegration and induction of periodontitis Seven weeks after the implantation -Group (1): 2 rats will be sacrificed and osteointegration and inflammatory markers will be examined. -Group (2): 2 rats will receive suture ligature at the cervical part of each implant. -Group (3): 2 rats will receive no ligature as a control. All the procedures will be performed when rats are und...

Materials and methods : Is maxillary diastema an a...

Titanium bone screw with machined surface 1.2 × 4.5 mm (screw head 1.5 mm, fixture 3 mm) was purchased from ACS Surgical Supply (Brockton, MA) that was used as implant by Freire and coworkers [15]. Six Sprague-Dawley, male, 400–450 g in which the body weight is based on reported article [15]. To achieve a stable implantation, the thickness of alveolar bone is crucial. Therefore, body wei...

Background : Is maxillary diastema an appropriate ...

To create a clinically compatible rat model for implantation, we have done a comprehensive literature review of rat dental implant models. Implants placed out of oral cavity such as the femur [9,10,11] and the tibia [12, 13], or not on the ridge of alveolar bone, i.e., the ramus of mandibular [14] is not considered in the present experiment because these implantations are not clinically comparable...

Background : Is maxillary diastema an appropriate ...

Implantology or implant dentistry is a fast-growing industry. It is reported that the global dental implant market was valued at $ 3.77 billion in 2016 growing at a compound annual growth rate (CAGR) of 7.7% over the forecast period (2018–2024) [1]. The USA holds a substantial market share due to the growing demand of dental implant treatment (Grand View Research, 2018, Figs 1 and 2). The 2009 a...

Highlights : Is maxillary diastema an appropriate ...

Current study indicates that maxillary nature diastema could be a site to place implant, but it has a low successful rate. Data indicate that the true success rate of implantation in maxillary natural diastema in rat is less than 38.4% at a confident level of 95%. Therefore, it is not an appropriate site for dental implant experiment. Moreover, it may be able to form certain osseointegration, but ...

Abstract : Is maxillary diastema an appropriate si...

Implantology or implant dentistry is growing fast during last four decades. Facing the growing demand of implant treatment, there are extreme challenges to clinicians and researchers. First is peri-implantitis with remarkable prevalence. Though investigators have revealed that the etiology of the peri-implant infection is similar to periodontitis, clinically there is no effective treatment. Second...

Fig. 9. Scatter diagrams illustrating the distribu...

Fig. 9. Scatter diagrams illustrating the distribution of angle deviation of each protocol. a Anterior implants. b Posterior implants Fig. 9. Scatter diagrams illustrating the distribution of angle deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 8. Box plot diagrams illustrating the distrib...

Fig. 8. Box plot diagrams illustrating the distribution of maximum angle deviation of each protocol. a Anterior implants. b Posterior implants Fig. 8. Box plot diagrams illustrating the distribution of maximum angle deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 7. Scatter diagrams illustrating the distribu...

Fig. 7. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants Fig. 7. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 6. Box plot diagrams illustrating the distrib...

Fig. 6. Box plot diagrams illustrating the distribution of maximum horizontal apex deviation of each protocol. a Anterior implants. b Posterior implants Fig. 6. Box plot diagrams illustrating the distribution of maximum horizontal apex deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 5. Scatter diagrams illustrating the distribu...

Fig. 5. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants Fig. 5. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 4. Box plot diagrams illustrating the distrib...

Fig. 4. Box plot diagrams illustrating the distribution of maximum horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants Fig. 4. Box plot diagrams illustrating the distribution of maximum horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 3. Box plot diagrams illustrating the distrib...

Fig. 3. Box plot diagrams illustrating the distribution of vertical deviation of each protocol. a Anterior implants. b Posterior implants Fig. 3. Box plot diagrams illustrating the distribution of vertical deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 2. a Schematic diagram illustrating the measu...

Fig. 2. a Schematic diagram illustrating the measurement of vertical, horizontal neck, horizontal apex, and angle deviations. b Three forms of horizontal deviation were measured: maximum, mesiodistal, and buccolingual directions Fig. 2. a Schematic diagram illustrating the measurement of vertical, horizontal neck, horizontal apex, and angle deviations. b Three forms of horizontal deviation we...

Fig. 1. Flowchart summarizing the different phases...

Fig. 1. Flowchart summarizing the different phases of the experiment Fig. 1. Flowchart summarizing the different phases of the experiment

Table 1 Summary of implant vertical, horizontal an...

 Vertical implant deviation  Anterior implantPosterior implantp values between anterior and posterior implants FGPGFHFGPGFHMean (mm)0.210.530.300.340.640.49FG = 0.07SD (mm)0.120.520.240.230.370.22PG = 0.27Maximum (mm)0.391.650.810.801.130.80FH = 0.05Minimum (mm)0.090.050.070.040.200.07p valuesAll groups = 0.12All groups = 0.08  Maximum horizontal implant neck deviation ...

About this article : Accuracy of static computer-a...

Abduo, J., Lau, D. Accuracy of static computer-assisted implant placement in anterior and posterior sites by clinicians new to implant dentistry: in vitro comparison of fully guided, pilot-guided, and freehand protocols. Int J Implant Dent 6, 10 (2020). https://doi.org/10.1186/s40729-020-0205-3 Download citation Received: 31 October 2019 Accepted: 21 January 2020 Published: 11 March 2020 DOI:...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Accuracy of static comput...

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Ethics declarations : Accuracy of static computer-...

This study was approved by the University of Melbourne Human Research Ethics Committee (1851406.1). The study complied with the Declaration of Helsinki. All participants were aware of the nature of the study and provided their consent prior to the commencement of the study. Not applicable Jaafar Abduo, and Douglas Lau declare that they have no competing interests.

Author information : Accuracy of static computer-a...

Associate Professor in Prosthodontics, Convenor of Postgraduate Diploma in Clinical Dentistry (Implants), Melbourne Dental School, Melbourne University, 720 Swanston Street, Melbourne, VIC, 3010, Australia Jaafar Abduo Periodontist, Private Practice, Melbourne University, Melbourne, VIC, Australia Douglas Lau You can also search for this author in PubMed Google Scholar You can also search fo...

Funding : Accuracy of static computer-assisted imp...

The implants, surgical kits, and guide sleeves were provided by Straumann Australia. This study has been funded by the Kernot Early Career Researcher Award. No financial income for conducting the study was received by the authors.

Acknowledgements : Accuracy of static computer-ass...

The authors would also like to thank Mr. Attila Gergely for his technical support in developing the simulated case and the input of the team of Digital Dental Network in designing the guides.

References : Accuracy of static computer-assisted ...

Deeb GR, Allen RK, Hall VP, Whitley D 3rd, Laskin DM, Bencharit S. How accurate are implant surgical guides produced with desktop stereolithographic 3-dimentional printers? J Oral Maxillofac Surgery. 2017;75:2551–9. Horwitz J, Zuabi O, Machtei EE. Accuracy of a computerized tomography-guided template-assisted implant placement system: an in vitro study. Clin Oral Implants Res. 2009;20:1156–62...

References : Accuracy of static computer-assisted ...

Rungcharassaeng K, Caruso JM, Kan JY, Schutyser F, Boumans T. Accuracy of computer-guided surgery: a comparison of operator experience. J Prosthet Dent. 2015;114:407–13. Park SJ, Leesungbok R, Cui T, Lee SW, Ahn SJ. Reliability of a CAD/CAM surgical guide for implant placement: an in vitro comparison of surgeons' experience levels and implant sites. Int J Prosthodont. 2017;30:367–9. Marheine...

References : Accuracy of static computer-assisted ...

Belser UC, Mericske-Stern R, Bernard JP, Taylor TD. Prosthetic management of the partially dentate patient with fixed implant restorations. Clin Oral Implants Res. 2000;11:126–45. Buser D, Martin W, Belser UC. Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants. 2004;19:43–61. Ramaglia L, Toti P, Sbordone...

Abbreviations : Accuracy of static computer-assist...

Three-dimensional Computer-aided design/computer-aided manufacturing Cone beam computed tomography Digital Imaging and Communications in Medicine Fully guided Freehand Pilot-guided Static computer-assisted implant placement Surface tessellation language

Availability of data and materials : Accuracy of s...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Accuracy of static computer-assisted...

Within the limitations of the present study, it can be hypothesized that apart from vertical deviation, the FG protocol is more accurate than the PG and FH protocols for all the evaluated variables in the hands of inexperienced clinicians. The PG and FH protocols were generally similar. The FG protocol did not seem to be influenced by the position of the placed implants, while the PG and FH protoc...

Discussion : Accuracy of static computer-assisted ...

For the majority of the evaluated variables, there was a tendency for the posterior implants to suffer from more deviation than anterior implants. This is in accordance with several published reports [5, 21, 22]. Interestingly, implants placed by the FG protocol seemed to be less vulnerable to inaccuracy by changing the implant sites, while the PG and FH protocols showed more horizontal and angle ...

Discussion : Accuracy of static computer-assisted ...

The superior accuracy and the less variation of the FG protocol is most likely related to the control of all the drilling steps and the implant placement via sequential use of precision sleeves. This eliminated the manual orientation and handling of the drills at any stage of drilling or implant placement. In accordance with these observations, Noharet et al. reported a better accuracy of the FG p...

Discussion : Accuracy of static computer-assisted ...

The overall outcome of this study indicates the superiority of the FG protocol in comparison to PG and FH protocols for placing single implants. With the exception of vertical deviation, this was obvious for horizontal neck, horizontal apex, and angle deviations that were closer to the planned implant for the FG protocol than the other protocols. In addition, this superiority was shown for anterio...

Results : Accuracy of static computer-assisted imp...

In relation to the maximum angle deviation (Fig. 8), the FG protocol had less deviation than the other protocols for anterior (2.42 ± 0.98°) and posterior (2.61 ± 1.23°) implants. The PG (4.65 ± 1.78°) and FH (4.79 ± 2.08°) protocols were similar for anterior implant placement, while the FH protocol seemed more accurate for posterior implants (4.77 ± 2.09°) than the ...

Results : Accuracy of static computer-assisted imp...

In general, for all the variables, there was a tendency for the FG protocol to yield more accurate implant placement than other protocols (Table 1). In relation to vertical deviation, the PG protocol seemed to be associated with more errors. However, there was no significant difference in vertical deviation among all the protocols. Figure 3 indicates that the PG protocol was associated with deep...

Methods : Accuracy of static computer-assisted imp...

The vertical deviation was measured by calculating the discrepancy along the long axis of the planned implant at the center of the platform (Fig. 2a). In addition to the magnitude of the deviation, the direction of the error was determined. The horizontal deviations were measured at the neck and the apex of the planned implant. The angle deviation was computed by measuring the angle of the long a...

Methods : Accuracy of static computer-assisted imp...

For all the protocols, straight bone level Straumann dummy implants were planned. The anterior implants were 4.1 × 10 mm, while the posterior implants were 4.8 × 10 mm. The anterior implants were planned to be placed 2 mm subcrestal, while the posterior implants were planned to be placed 1 mm subcrestal. For the conventional protocols, the clinicians had access to physical intact Ni...

Methods : Accuracy of static computer-assisted imp...

The soft tissue silicone former was removed from the Nissin model to simulate bone anatomy. Subsequently, this model was duplicated with clear resin material mixed with barium sulfate and scanned by a cone beam computed tomography (CBCT) machine to generate cross-sectional DICOM images. The DICOM images were imported to the implant planning software programs. For the FH protocol, the 2D DICOM ima...

Methods : Accuracy of static computer-assisted imp...

A total of 10 qualified clinicians with a minimum of 3 years of general practice experience were invited to participate in the study. The number of participants was similar to previously published studies [12, 19], and was confirmed by sample size calculation. A mean horizontal deviation of 1 mm and an expected standard deviation of 0.75 mm that were reported from earlier studies [13, 19] were ...

Background : Accuracy of static computer-assisted ...

Despite all the advantages of sCAIP protocols, several studies reported that they are still prone to errors and complications [7,8,9, 17, 18]. The FG and PG protocols still require thorough planning and surgical understanding and skills [11]. For multiple implants and long-span edentulous ridges, guided surgery has the advantages of being more reliable, more comfortable for the patient, and more r...

Background : Accuracy of static computer-assisted ...

Implant treatment is a growing field in dentistry, and many clinicians aim to increase their scope of practice by including such treatment. One of the main challenges encountered by clinicians new to implant dentistry is the determination and controlling of implant location. It is the consensus that implant placement must be planned to achieve an acceptable position for an ideal restorative outcom...

Abstract : Accuracy of static computer-assisted im...

One of the challenges encountered by clinicians new to implant dentistry is the determination and controlling of implant location. This study compared the accuracy of fully guided (FG) and pilot-guided (PG) static computer-assisted implant placement (sCAIP) protocols against the conventional freehand (FH) protocol for placing single anterior and posterior implants by recently introduced clinicians...

Fig. 3. Histological magnifications of specimens e...

Fig. 3. Histological magnifications of specimens exposing a significant areas of lamellar bone in-between and parallel to the surface of older trabeculae (accentuated by green overlay), b osteoclastic activity, and c active bone formation at intrabony marginal regions Fig. 3. Histological magnifications of specimens exposing a significant areas of lamellar bone in-between and parallel to the ...

Fig. 2. Histological view (buccal aspect) displayi...

Fig. 2. Histological view (buccal aspect) displaying mean BIC (%) and mean bone density (%) at corresponding regions (500 μm zones) from BD to A. Blue lines along the implant perimeter display BIC presence and yellow lines display BIC absence Fig. 2. Histological view (buccal aspect) displaying mean BIC (%) and mean bone density (%) at corresponding regions (500 μm zones) from BD to A. Blue...

Fig. 1. Histological section illustrating the land...

Fig. 1. Histological section illustrating the landmarks to determine the conducted histomorphometrical length measurements: DL, RB, and BIC at buccal RB. The red square frames the intra-thread area (ROI) for OD and ELD analysis Fig. 1. Histological section illustrating the landmarks to determine the conducted histomorphometrical length measurements: DL, RB, and BIC at buccal RB. The red squar...

Table 3 Mean osteocyte (OD) and empty lacunae dens...

SP ID Mean OD (number/mm2)Mean ELD (number/mm2)Osteocyte/empty lacuna ratio12932311.2622211021.3231122450.4541721021.6851621431.12Mean1921651.17SD ±6869.20.4595% CI(132–251)(103–225) Table 3 Mean osteocyte (OD) and empty lacunae density (ELD) at peri-implant residual bone

Table 2 Results from histomorphometric measurement...

Specimen IDDL (mm)RB (mm)B.Ar/T.Ar (%)BIC (%)14.83.572.480.025.68.992.375.035.65.388.173.843.87.781.868.753.63.292.571.1Mean4.75.785.574.0SD ±1.02.58.04.095% CI3.1–4.93.3–6.878–9270.6–77.6Table 2 Results from histomorphometric measurements exhibiting DL, RB, bone density (%), residual bone-to-implant contact (%) values

Table 1 Patient and implant site characteristics :...

Sample ID Gender Age Location Prosthesis type Loading time (years) lmplant surface Mean BOP (%) Supp (+/−) Mean PD (mm) MBL (mm) 1 M 69 Maxilla Single-screwed 5.1 Machined 100 + 6.4 B: 4.0P: 6.0 2 F 60 Mandible Single-screwed 10.0 Machined 100 − 6.0 B: 4.5L: 5.0 3 F 60 Mandible Single-screwed 10.0 Machined 100 − 6.2 B: 4.0L: 5...

About this article : Histological characteristics ...

Galárraga-Vinueza, M., Tangl, S., Bianchini, M. et al. Histological characteristics of advanced peri-implantitis bone defects in humans. Int J Implant Dent 6, 12 (2020). https://doi.org/10.1186/s40729-020-00208-8 Download citation Received: 08 January 2020 Accepted: 19 February 2020 Published: 25 March 2020 DOI: https://doi.org/10.1186/s40729-020-00208-8

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Histological characterist...

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Ethics declarations : Histological characteristics...

The study protocol no. 3437751 was approved by the Human Research Committee at Federal University of Santa Catarina-Brazil, 2016–2021, and all patients signed an informed consent according to the university ethics regulations. Not applicable The authors declare that they have no competing of interests.

Author information : Histological characteristics ...

MG, FS, RG, and MB contributed to the design of the study. ST and KO contributed to study selection and data extraction. MG, RM, FS, RG, MB, ST, and KO contributed to the drafting of the paper and revising it critically. All authors read, revised, and approved the final manuscript. Correspondence to Reinhard Gruber.

Author information : Histological characteristics ...

Department of Oral Surgery and Implantology, Carolinum, Goethe University, Frankfurt, Germany Maria Elisa Galárraga-Vinueza, Karina Obreja & Frank Schwarz Post-Graduate Program in Implant Dentistry (PPGO), Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil Maria Elisa Galárraga-Vinueza, Marco Bianchini & Ricardo Magini Core Facility Hard Tissue and Biomaterial Rese...

Funding : Histological characteristics of advanced...

The present study was funded by the authors’ own departments.

Acknowledgements : Histological characteristics of...

Not applicable

References : Histological characteristics of advan...

Kohal R-J, Patzelt SBM, Butz F, Sahlin H. One-piece zirconia oral implants: one-year results from a prospective case series. 2. Three-unit fixed dental prosthesis (FDP) reconstruction. J Clin Periodontol [Internet]. 2013 [cited 2018 Nov 15];40(5):553–562. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23506654. Dallas SL, Prideaux M, Bonewald LF. The osteocyte: an endocrine cell ... and mor...

References : Histological characteristics of advan...

Berglundh T, Gislason O, Lekholm U, Sennerby L, Lindhe J. Histopathological observations of human periimplantitis lesions. J Clin Periodontol [Internet]. 2004 [cited 2019 Mar 13];31(5):341–347. Available from: http://doi.wiley.com/10.1111/j.1600-051X.2004.00486.x. Zitzmann NU, Berglundh T, Ericsson I, Lindhe J. Spontaneous progression of experimentally induced periimplantitis. J Clin Periodonto...

References : Histological characteristics of advan...

Schwarz F, Herten M, Sager M, Bieling K, Sculean A, Becker J. Comparison of naturally occurring and ligature-induced peri-implantitis bone defects in humans and dogs. Clin Oral Implants Res [Internet]. 2007 [cited 2019 Mar 18];18(2):161–170. Available from: http://doi.wiley.com/10.1111/j.1600-0501.2006.01320.x. Serino G, Turri A, Lang NP. Probing at implants with peri-implantitis and its relati...

References : Histological characteristics of advan...

Schwarz F, Derks J, Monje A, Wang H-L. Peri-implantitis. J Clin Periodontol. 2018;45(June 2016):S246–66. Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, et al. Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 World Workshop on the classification of periodontal and peri-implant diseases and conditions. J Clin Periodontol [Internet]. 2018 ...

Abbreviations : Histological characteristics of ad...

Most apical extension of the residual bone tissue Bone area Bone defect Bone-to-implant contact Bleeding on probing Cone beam computed tomography Confidence interval Disto-buccal Defect length Disto-oral Empty lacuna density Implant shoulder Mesio-buccal Marginal bone loss Mesio-oral Oral Osteocyte density Probing depth Residual bone Region of interest Surface area Standard de...

Availability of data and materials : Histological ...

The data sets used and/or analyzed during the current study are available from the corresponding author or reasonable request.

Conclusions : Histological characteristics of adva...

In conclusion, the findings of this case series based on dental implants that had to be retrieved because of advanced peri-implantitis and the concomitant inflammatory osteolysis suggest that the residual peri-implant bone might accumulate the functional load and is consequently modeled and reinforced to become cortical bone.

Discussion : Histological characteristics of advan...

When further interpreting the present study, the peri-implant osteocyte lacunae density after 1 to 27 years in function was reported [28]. In line with our findings, empty osteocytic lacunae adjacent to zirconia implants diagnosed with peri-implantitis were described [29]. Based on counting the osteocyte lacunae, we observed that numerous filled but also empty osteocytic lacunae were present withi...

Discussion : Histological characteristics of advan...

The present study was inspired by the concept that upon advanced loss of cortical peri-implant bone, the remaining peri-implant trabecular bone is subjected to masticatory forces and reinforced as a consequence of functional adaptation [15]. This adaptation depends on vital osteocytes [16]. Therefore, the present human case series aimed at investigate the peri-implant bone in advanced peri-implant...

Results : Histological characteristics of advanced...

The clinical and radiographic characteristics of the implant sites are presented in Table 1. In total, 3 implants were located in the maxilla, while two implants were located in the mandible. While all implants showed bleeding on probing, only 2 implants presented with suppuration on gentle probing. Mean probing depth was 6.3 ± 0.4 mm corresponding to a mean marginal bone loss (MBL) of 4.7 ± 1.0...

Materials and methods : Histological characteristi...

RB was divided into 500-μm-wide horizontal zones (from BD to A) following the long axis of the implant. For each of these individual zones, BIC and bone density (B.Ar/T.Ar) were determined. Osteocyte and empty osteocytic lacunae were counted along the region of interest (ROI) (i.e., the area encompassing the intra-thread regions along the buccal RB extension) (Fig. 1) using a software program (Im...

Materials and methods : Histological characteristi...

Cone beam computed tomographic (CBCT) scans were obtained from each patient for the surgical planning of implant removal. Linear measurements of the defect length (DL) at affected implants were made by drawing a vertical line, following the long axis of the implant, from the implant shoulder (IS) to the bottom of the defect (BD) at buccal and oral aspects in the CBCT data sets (Implant viewer, ver...

Materials and methods : Histological characteristi...

The present study included 4 patients, 3 female and 1 male (mean age of 66 ± 5 years), who attended the Implant Dentistry Department at Federal University of Santa Catarina, complaining of pain, discomfort, suppuration, and/or bleeding at implant sites. All patients revealed a history of periodontal disease, were non-smokers (100%), and reported no additional systemic diseases. The patients exhi...

Background : Histological characteristics of advan...

Peri-implantitis was recently defined as a “pathological condition occurring in tissues around dental implants”, which is “characterized by inflammation in the peri-implant connective tissue and a progressive loss of supporting bone” [1,2,3,4]. Human biopsies confirmed the presence of plasma cells, macrophages, and neutrophils [5] and elevated expression of inflammatory cytokines [6, 7] a...

Abstract : Histological characteristics of advance...

Inflammatory osteolysis is the clinical hallmark of peri-implantitis. The morphology of the remaining peri-implant bone and the level of osseointegration, however, remain unknown. Our aim was to characterize advanced peri-implantitis bone defects in humans. Four patients (3 female and 1 male) were diagnosed with peri-implantitis. A total of 5 implants with machined surfaces and a mean loading tim...

Fig. 7. The box plot shows the distribution of age...

Fig. 7. The box plot shows the distribution of age between the sex groups Fig. 7. The box plot shows the distribution of age between the sex groups

Fig. 6. Pie chart shows the distribution of loaded...

Fig. 6. Pie chart shows the distribution of loaded implants prosthetic restorations Fig. 6. Pie chart shows the distribution of loaded implants prosthetic restorations

Fig. 5. Pie charts shows the distribution of the d...

Fig. 5. Pie charts shows the distribution of the demographic datas of the patients Fig. 5. Pie charts shows the distribution of the demographic datas of the patients

Fig. 4. The crown-implant ratio measurement showin...

Fig. 4. The crown-implant ratio measurement showing a the length of the crown (red line) and b the length of the implant (red line) Fig. 4. The crown-implant ratio measurement showing a the length of the crown (red line) and b the length of the implant (red line)

Fig. 3. Fractal analysis stages. a Selected region...

Fig. 3. Fractal analysis stages. a Selected region of interest (ROI). b Cropped and duplicated version of ROI. c Addition of Gaussian filter. d Subtraction. e Addition of 128 pixels. f Binarized version. g Eroded version. h Dilated version. i Inverted version j Skeletonization Fig. 3. Fractal analysis stages. a Selected region of interest (ROI). b Cropped and duplicated version of ROI. c Addi...

Fig. 2. Region of interests (ROIs) were selected a...

Fig. 2. Region of interests (ROIs) were selected arbitrarily in a preoperative radiographic image and b a follow-up radiographic image Fig. 2. Region of interests (ROIs) were selected arbitrarily in a preoperative radiographic image and b a follow-up radiographic image

Fig. 1. Fractal dimension values measured from th...

Fig. 1. Fractal dimension values measured from the same area of interest on each panoramic radiograph over five different time intervals are shown in the figure. FD0, fractal dimension 0 (preoperative); FD1, fractal dimension 1 (0–1 months of follow-up); FD2, fractal dimension 2 (1–3 months of follow-up); FD3, fractal dimension 3 (6–12 months of follow-up); FD4, fractal dimension 4 ...

Table 2 Mean fractal dimension (FD) values before ...

 nMeanStandard deviationMinimumMaximumFD01301.2430.1520.7501.560FD11301.1130.2240.4051.510FD21301.1160.1960.4101.510FD3671.0920.2160.4301.500FD4671.0810.2470.4301.500Table 2 Mean fractal dimension (FD) values before and after implant insertion

Table 1 Distribution and description of FD1 and FD...

 Failure (n)Success (n)P valuePowerEffect sizeSexWomen3870.0240.680.21Men634FD190.82 ± 0.28 (mean)0.45 (min)–1.26 (max)1211.13 ± 0.25 (mean)0.41 (min)–1.51 (max)< 0.0010.991.45FD290.97 ± 0.24 (mean)0.61 (min)–1.36 (max)1211.13 ± 0.19 (mean)0.41 (min)–1.51 (max)0.0230.990.79Crown-implant Ratio26.51 ± 3.89 (mean)3.77 (min)–9.27 (max)654.61 ± 1.58 (mean)2.57 min)–10.67 (max)0.101...

About this article : Evaluation of the peri-implan...

Kış, H.C., Güleryüz Gürbulak, A. Evaluation of the peri-implant bone trabecular microstructure changes in short implants with fractal analysis. Int J Implant Dent 6, 13 (2020). https://doi.org/10.1186/s40729-020-00209-7 Download citation Received: 12 September 2019 Accepted: 12 March 2020 Published: 01 April 2020 DOI: https://doi.org/10.1186/s40729-020-00209-7

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

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Ethics declarations : Evaluation of the peri-impla...

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study. Hatice Cansu Kış and Ayşegül Güleryüz Gür...

Author information : Evaluation of the peri-implan...

Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Nuh Naci Yazgan University, Kayseri, Turkey Hatice Cansu Kış Department of Prosthetic Dentistry, Faculty of Dentistry, Erciyes University, Kayseri, Turkey Ayşegül Güleryüz Gürbulak You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar AGG collecte...

Funding : Evaluation of the peri-implant bone trab...

The work was supported by the Department of Oral & Maxillofacial Radiology, Nuh Naci Yazgan University in Kayseri, Turkey.

Acknowledgements : Evaluation of the peri-implant ...

We would like to thank Editage (www.editage.com) for English language editing.

References : Evaluation of the peri-implant bone t...

Download references

References : Evaluation of the peri-implant bone t...

Mu T-J, Lee D-W, Park K-H, Moon I-S. Changes in the fractal dimension of peri-implant trabecular bone after loading: a retrospective study. Journal of periodontal & implant science. 2013;43(5):209–14. Zeytinoğlu M, İlhan B, Dündar N, Boyacioğlu H. Fractal analysis for the assessment of trabecular peri-implant alveolar bone using panoramic radiographs. Clinical oral investigations. 2015;19(2...

References : Evaluation of the peri-implant bone t...

Mandelbrot BB. The fractal geometry of nature: WH freeman New York; 1983. Sánchez I, Uzcátegui G. Fractals in dentistry. Journal of dentistry. 2011;39(4):273–92. Boutroy S, Bouxsein ML, Munoz F, Delmas PD. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. The Journal of Clinical Endocrinology & Metabolism. 2005;90(12):6508...

Abbreviations : Evaluation of the peri-implant bon...

Dental panoramic radiographs Fractal dimension 0 (preoperative) Fractal dimension 1 (0–1 months of follow-up) Fractal dimension 2 (1–3 months of follow-up) Fractal dimension 3 (6–12 months of follow-up) Fractal dimension 4 (12 + months of follow-up) Cone beam computed tomography Region of interest

Availability of data and materials : Evaluation of...

Not Applicable

Conclusion : Evaluation of the peri-implant bone t...

Fractal analysis is a useful method to measure the trabecular microstructure of bone in nonstandardized dental radiographs. The present study has a low power to reject the null hypothesis because of the low number of cases of failed implants. Therefore, further studies with a large sample size are warranted. Assessing a series of studies can provide certain cut-off values; this can enable to routi...

Discussion : Evaluation of the peri-implant bone t...

Fractal analysis of bone microstructure on dental radiographs may be useful for diagnostic applications; however, the histological microstructures of the bone cannot be visualized by any clinical imaging modality. Corpas et al. [12] stated that minor changes in bone occurring over a short-term period can be followed up with digital intraoral radiography; however, the results of radiographic fracta...

Discussion : Evaluation of the peri-implant bone t...

This study aimed to evaluate the microstructural changes in the peri-implant bone in patients with short implants in terms of the implant survival status by using fractal analysis measurements. In this study, a significant difference was found in the FD1 and FD2 values between the implant survival groups, and the mean FD1 and FD2 values of the success group were significantly higher than those of...

Results : Evaluation of the peri-implant bone trab...

Descriptive statistics were performed. The data were not normally distributed (p < 0.05). The intra-observer correlation coefficients of repeated measurements were 0.927, 0.889, 0.913, 0.988, 0.961, and 0.936 for FD0 (fractal dimension), FD1, FD2, FD3, FD4, and crown-implant ratio, respectively. Descriptive data are shown in Figs. 5, 6, and 7. A significant difference was found for sex between the...

Materials and methods : Evaluation of the peri-imp...

The crown-implant ratio was measured using the ImageJ version 1.38 software measuring tool in conjunction with a magnification tool. Each implant was measured from its bottom to the crown base and then from the crown base to its highest point (Fig. 4). All measurements were performed by a dento-maxillofacial radiologist who was blinded to patient information. To evaluate the intra-observer correl...

Materials and methods : Evaluation of the peri-imp...

This retrospective study was conducted in the dental clinic of Oral and Maxillofacial Radiology department and was approved by the local ethics committee (2013/203). The participants had approached the Prosthodontics Clinic between 2012 and 2019 for partial or complete tooth complaints. Among the data of 116 patients reviewed, panoramic radiographs of 67 patients were examined and included in this...

Backgrounds : Evaluation of the peri-implant bone ...

The quality of bone tissue at the site of implantation can be determined preoperatively with high accuracy, and changes in the trabecular structure, which is vital for the primary and secondary stability of the implant, can be observed during the follow-up after implantation. Previous studies have evaluated fractal analysis of peri-implant bone before and after loading. However, no study has exam...

Backgrounds : Evaluation of the peri-implant bone ...

Mandelbrot introduced fractals to describe his observation of shapes in nature, such as curves, surfaces, disconnected “dust,” and odd shapes. The word fractal originates from the Latin word “fractus,” which means broken. By using fractal mathematics, several studies have analyzed various fractal patterns in the human body. Fractal analysis is a mathematical method of describing complex sh...

Abstract : Evaluation of the peri-implant bone tra...

This study aimed to evaluate the microstructural changes in the peri-implant bone in patients with short implants in terms of implant survival status by using fractal analysis measurements. Dental panoramic radiographs (DPRs) of 67 patients were examined and included in this study. Fractal analysis and measurement of the crown-implant ratio were performed with ImageJ. The fractal analysis measure...

Fig. 5. PROMs over 5 years: improvement of satis...

Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end

Fig. 4. Soft tissue parameters at 5-year post-load...

Fig. 4. Soft tissue parameters at 5-year post-loading. a Plaque index: score 0, no plaque detected; score 1, plaque only recognized by running a probe across the smooth marginal surface of the implant; score 2, plaque seen by the naked eye; score 3, abundance of soft matter. b Sulcus bleeding index: score 0, no bleeding when a periodontal probe was passed along the gingival margin adjacent to th...

Fig. 3. Standardized peri-apical radiographs repre...

Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5-year post-loading (c) Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5...

Fig. 2. Kaplan-Meier cumulative survival rate : Cl...

Fig. 2. Kaplan-Meier cumulative survival rate Fig. 2. Kaplan-Meier cumulative survival rate

Fig. 1. Study flow-chart: assessments and reason f...

Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits

Table 3 Mean crestal bone level changes in mm : Cl...

Bone level changenMeanSDInsertion-loading103− 0.520.55Loading-1-year follow-up93− 0.040.37Loading-3-year follow-up90− 0.040.40Loading-5-year follow-up86− 0.090.43Table 3 Mean crestal bone level changes in mm

Table 2 Demography of study population : Clinical ...

CharacteristicsCategoryTotalTotal patients/implantsn94/130Center 19/17Center 218/26Center 320/26Center 414/16Center 518/26Center 615/19Gender, n (%)Male30 (31.9)Female64 (68.1)Age at surgery, yearsMean ± SD50.4 ± 13.7Range (min/max)19.1-75.6Age range distribution, n (%)< 30 years8 (8.5)30-45 years22 (23.4)45-60 years38 (40.4)60-75 years25 (26.6)> 75 years1 (1.1)Tobacco use, n (%)Non-sm...

Table 1 Dropouts over observation time : Clinical ...

Time periodPatientsImplantsBefore loading58Loading-1 year681-3 years673-5 years13Total1826Table 1 Dropouts over observation time

About this article : Clinical and patient-reported...

Ackermann, KL., Barth, T., Cacaci, C. et al. Clinical and patient-reported outcome of implant restorations with internal conical connection in daily dental practices: prospective observational multicenter trial with up to 7-year follow-up. Int J Implant Dent 6, 14 (2020). https://doi.org/10.1186/s40729-020-00211-z Download citation Received: 16 December 2019 Accepted: 12 Ma...

Rights and permissions : Clinical and patient-repo...

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Clinical and patient-repo...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Clinical and patient-reporte...

A written consent was given by all patients after being informed of the study. The study was performed following the declaration of Helsinki. Ethics committee approval was obtained from the international ethical committee of Freiburg (Germany, Ref. 010/1833). Not applicable. All authors declare that they have no conflicts of interest regarding this study. All authors have been lecturing for Caml...

Author information : Clinical and patient-reported...

Filderstadt, Germany Karl-Ludwig Ackermann Leipzig, Germany Thomas Barth Munich, Germany Claudio Cacaci Landsberg a. L., Germany Steffen Kistler Forchheim, Germany Markus Schlee Department of Maxillofacial Surgery, Goethe University Frankfurt, Frankfurt, Germany Markus Schlee Berlin, Germany Michael Stiller You can also search for this author in PubMed Googl...

Funding : Clinical and patient-reported outcome of...

This study was funded by an unrestricted grant (NISCAM01/10) of the Oral Reconstruction Foundation (previously CAMLOG Foundation).

Acknowledgements : Clinical and patient-reported o...

The authors thank Lucius Keller of Touchpoint Communication AG (Luzern, Switzerland) for the medical writing support.

References : Clinical and patient-reported outcome...

Chang M, Odman PA, Wennstrom JL, Andersson B. Esthetic outcome of implant-supported single-tooth replacements assessed by the patient and by prosthodontists. Int J Prosthodont. 1999;12(4):335–41. Kiltz U, Winter J, Schirmer M, Weber U, Hammel L, Baraliakos X, et al. German translation and cross-cultural adaptation of the ASAS health index: an ICF-based instrument for documentation of functional...

References : Clinical and patient-reported outcome...

Ravald N, Dahlgren S, Teiwik A, Grondahl K. Long-term evaluation of Astra Tech and Branemark implants in patients treated with full-arch bridges. Results after 12-15 years. Clin Oral Implants Res. 2013;24(10):1144–51. Schwarz F, Alcoforado G, Nelson K, Schaer A, Taylor T, Beuer F, et al. Impact of implant-abutment connection, positioning of the machined collar/microgap, and platform switching...

References : Clinical and patient-reported outcome...

Gupta S, Sabharwal R, Nazeer J, Taneja L, Choudhury BK, Sahu S. Platform switching technique and crestal bone loss around the dental implants: a systematic review. Ann Afr Med. 2019;18(1):1–6. Hsu YT, Lin GH, Wang HL. Effects of platform-switching on peri-implant soft and hard tissue outcomes: a systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2017;32(1):e9–e24. Nelson K,...

References : Clinical and patient-reported outcome...

Cacaci C, Ackermann KL, Barth T, Kistler S, Stiller M, Schlee M. A non-interventional multicenter study to document the implants success and survival rates in daily dental practices of the CONELOG screw-line implant. Clin Oral Investig. 2019;23(6):2609–16. Cochran D, Oates T, Morton D, Jones A, Buser D, Peters F. Clinical field trial examining an implant with a sand-blasted, acid-etched surface...

References : Clinical and patient-reported outcome...

Krennmair G, Seemann R, Weinlander M, Piehslinger E. Comparison of ball and telescopic crown attachments in implant-retained mandibular overdentures: a 5-year prospective study. Int J Oral Maxillofac Implants. 2011;26(3):598–606. Slot W, Raghoebar GM, Cune MS, Vissink A, Meijer HJA. Four or six implants in the maxillary posterior region to support an overdenture: 5-year results from a randomize...

Abbreviations : Clinical and patient-reported outc...

Adverse event Bone level change Distance implant shoulder to first visible bone contact Orthopantomogram Plaque index Patient reported outcome measures Platform switching Sulcus bleeding index

Availability of data and materials : Clinical and ...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Clinical and patient-reported outcom...

This prospective observational multicenter study demonstrated successful functional and esthetic outcomes of the study implant restorations (single tooth restoration, fixed partial dentures) with reliable peri-implant hard and soft tissue stability and high patients’ satisfaction. The results are comparable with the outcome of already published controlled randomized clinical studies and retrospe...

Discussion : Clinical and patient-reported outcome...

In recent years, patients’ needs have increased in terms of the esthetic and functional outcome of the dental restoration. PROMs have been reported in several studies and represent a well-described non-invasive method to measure patient’s satisfaction with these needs; however, they might present a lack of standardization [39, 40] due to the very subjective view on esthetics or functionality o...

Discussion : Clinical and patient-reported outcome...

Changes in crestal bone level are well-documented in the literature. Bone remodeling is reported to take place between surgery and loading. The reported changes are generally around 0.5 mm [17, 27, 30] but can reach more than 1 mm [31] in randomized or observational trials. The present study is well in accordance with these findings with its bone remodeling of − 0.52 ± 0.55 mm. Nearly 45%...

Discussion : Clinical and patient-reported outcome...

Endosseous dental implants are a commonly accepted treatment procedure and showed high survival and success rates as well as good functional performance in numerous clinical trials and retrospective analyses, also for Conelog implants as for their specific implant surface [17, 23, 26]. However, in general, one could argue that results of controlled clinical studies do not reflect the real situatio...

Results : Clinical and patient-reported outcome of...

Table 3 shows the mean bone level changes of the implants with available radiographs from insertion to 5-year post-loading. Bone remodeling around the implant was noticeable from surgery to loading, presenting a mean value of − 0.52 ± 0.55 mm. From loading to the 5-year follow-up, the mean change in crestal bone remained clinically stable (−0.09 ± 0.43 mm) (Fig. 3). Split into three g...

Results : Clinical and patient-reported outcome of...

The study was started with 94 patients with 130 implants. At the end of the study (5-year post-loading), 76 patients with 104 implants were considered for analysis. Dropouts were distributed over the time of the study as described in Table 1. The majority of dropouts occurred early in the study phase. The reasons for the dropouts were variable as described in Fig. 1. The demographic and clinica...

Methods : Clinical and patient-reported outcome of...

The study data, soft and hard tissue parameters as well as the PROMs were descriptively analyzed using IBM SPSS V25.0 (IBM Corp., Armonk, NY, USA): Categorical variables were shown with frequencies and mean values were used for continuous variables. Survival analysis was performed using Kaplan–Meier method. Time of loading was the study baseline as per protocol, and the statistical unit was the ...

Methods : Clinical and patient-reported outcome of...

Patients were scheduled to follow-ups at 6 months, 1-, 2-, 3-, 4-, and 5-year post-loading for the assessment of the study parameter (Fig. 1). Depending on the investigators’ standard post-operative protocol, follow-up appointments were scheduled slightly differently: One center skipped the control visits at 6 months. Additionally, due to the observational character of the study and the pati...

Methods : Clinical and patient-reported outcome of...

This is an observational multicenter clinical study, approved by the ethics committee of the Freiburg ethics commission international (feci 010/1833). The study was planned and conducted according to the German medical devices law, the Declaration of Helsinki, good clinical practice, and the reporting is aligned with the STROBE statement. A minimum of 90 to 100 patients were planned to be included...

Introduction : Clinical and patient-reported outco...

Features of the chosen implant system for a study may also influence the outcome of the treatment: The degree of the manufacturer’s tolerances of implants with a conical implant-abutment connection heightens the risk of a mispositioning of the abutment, which cannot be corrected by repeated torqueing. Platform switching (PS) implants tend to have a protective effect on hard implant tissue outcom...

Introduction : Clinical and patient-reported outco...

Many randomized controlled clinical trials have been published about dental implants. They have demonstrated long-term success in the rehabilitation of edentulous patients [1, 2] as well as patients with single or multiple teeth replacements [3, 4]. While this type of trials have an indispensable place in establishing a new product or a new operation technique regarding safety and efficacy, the r...

Abstract : Clinical and patient-reported outcome o...

The interpretation of the results of randomized clinical trials is often questioned in relation with daily circumstances in practices. This prospective observational multicenter study was instigated to reflect the need for information in real-life situations with dental implants with internal conical implant-abutment connection (Conelog implant system). The implants were followed up at least 5-yea...

Fig. 5. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 5. Anti-RANKL and anti-RANKL+miR-146a treatments decreased gingival mRNA expression of TNF-α and RANKL with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. Gingival tissues around ligatured implants and non-ligation implants were excised and processed for RT-qPCR analysis to determine mRNA level of TNF-α of WT mice (a) and TLR2/4 KO mice (b) (mean ± SD, n = ...

Fig. 4. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 4. Anti-RANKL and anti-RANKL+miR-146a treatments decreased the inflammatory cell infiltration of the implant gingival tissues with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. HE staining of the gingival tissue around implants were performed in the control group, ligation group, ligation with anti-RANKL antibody treatment group, and ligation with anti-RANKL ...

Fig. 3. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 3. Anti-RANKL and anti-RANKL+miR-146a treatments decreased TRAP-positive cell quantities with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. TRAP-positive cells (red color) with 3 or more nuclei were considered osteoclasts and were shown in the control group, ligation group, ligation with anti-RANKL antibody treatment group, and ligation with anti-RANKL antibo...

Fig. 2. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 2. Anti-RANKL and anti-RANKL+miR-146a treatments decreased ligature-induced bone resorption with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. Buccal side images of the defleshed skulls were taken of the control (non-ligation) group, ligation (non-treatment) group, ligation with anti-RANKL antibody (ligation+AR) treatment group, and ligation with anti-RANKL a...

Fig. 1. Mouse model of ligature-induced experiment...

Fig. 1. Mouse model of ligature-induced experimental peri-implantitis. (a) Tooth extraction: left maxillary first and second molars extracted at 4 weeks old and the tooth extraction socket healed well with smooth gingiva surface after 6 weeks post-extraction. Implant placement: implant was put in alveolar bone without flap elevation. Ligature placement: at 4 weeks post-implant, 7-0 ligatur...

Table 1 Success rate (SR) of osseointegrated impla...

 Total implantsLostLooseOsseointegratedSuccess rate (%)SR P valueWild type group60654981.670.595TLR2/4 KO group60445286.67Table 1 Success rate (SR) of osseointegrated implants 4 weeks after implant placement

About this article : RANKL blockade alleviates per...

Pan, K., Hu, Y., Wang, Y. et al. RANKL blockade alleviates peri-implant bone loss and is enhanced by anti-inflammatory microRNA-146a through TLR2/4 signaling. Int J Implant Dent 6, 15 (2020). https://doi.org/10.1186/s40729-020-00210-0 Download citation Received: 24 September 2019 Accepted: 12 March 2020 Published: 15 April 2020 DOI: https://doi.org/10.1186/s40729-020-00210-0

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Additional information : RANKL blockade alleviates...

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Ethics declarations : RANKL blockade alleviates pe...

Not applicable Not applicable Keqing Pan, Yang Hu, Yufeng Wang, Hao Li, Michele Patel, Danyang Wang, Zuomin Wang, and Xiaozhe Han certify that they do not have any commercial or associate interest that represents a conflict of interest in connection with the manuscript. The submitted work was not carried out in the presence of any personal, professional, or financial relationships that could pot...

Author information : RANKL blockade alleviates per...

You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar KP contributed to the conception and design; contributed to the acquisition, analysis, and interpretation of data; and drafted the manuscript. YH contributed to the conception and design, contributed to the acquisition, anal...

Author information : RANKL blockade alleviates per...

Department of Stomatology, The Affiliated Hospital of Qingdao University, College of Stomatology, Qingdao University, Qingdao, 266003, Shandong, China Keqing Pan Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, MA, 02142, USA Keqing Pan, Yang Hu, Yufeng Wang, Hao Li, Michele Patel & Xiaozhe Han Department of Oral Medicine, Ninth People...

Funding : RANKL blockade alleviates peri-implant b...

This study was supported by NIH NIDCR R01DE025255 and the Forsyth Institute FPILOT36 to X Han and the Forsyth Institute FPILOT52 to Y Hu.

Acknowledgements : RANKL blockade alleviates peri-...

Not applicable

References : RANKL blockade alleviates peri-implan...

Tu S, Zhong D, Xie W, Huang W, Jiang Y, Li Y. Role of toll-like receptor signaling in the pathogenesis of graft-versus-host diseases. Int J Mol Sci. 2016;17(8). Gaddis DE, Michalek SM, Katz J. TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B. J Immunol. 2011;186(10):5772–83. Zhang P, Liu J, Xu Q, et al. TLR2-dependent m...

References : RANKL blockade alleviates peri-implan...

Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity. 2011;34(5):637–50. Song GG, Kim JH, Lee YH. Toll-like receptor (TLR) and matrix metalloproteinase (MMP) polymorphisms and periodontitis susceptibility: a meta-analysis. Mol Biol Rep. 2013;40(8):5129–41. Lin J, Bi L, Yu X, et al. Porphyromonas gingivalis exacerbates ligat...

References : RANKL blockade alleviates peri-implan...

Shuto T, Wachi T, Shinohara Y, Nikawa H, Makihira S. Increase in receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio in peri-implant gingiva exposed to Porphyromonas gingivalis lipopolysaccharide. J Dent Sci. 2016;11(1):8–16. O'Connell MB. Prescription drug therapies for prevention and treatment of postmenopausal osteoporosis. J Manag Care Pharm. 2006;12(6 Suppl A):S10-19; ...

References : RANKL blockade alleviates peri-implan...

Bertin TJC, Thivichon-Prince B, LeBlanc ARH, Caldwell MW, Viriot L. Current perspectives on tooth implantation, attachment, and replacement in amniota. Front Physiol. 2018;9:1630. Schminke B, Vom Orde F, Gruber R, Schliephake H, Burgers R, Miosge N. The pathology of bone tissue during peri-implantitis. J Dent Res. 2015;94(2):354–61. Mombelli A, Muller N, Cionca N. The epidemiology of peri-impl...

Abbreviations : RANKL blockade alleviates peri-imp...

Receptor activator of nuclear factor-kappa Β ligand Toll-like receptor Wild type MicroRNA 146a Micro-computed tomography Real-time quantitative PCR Tumor necrosis factor alpha Osteoprotegerin Lipopolysaccharides Hematoxylin and eosin Tartrate-resistant acid phosphatase

Availability of data and materials : RANKL blockad...

Presented in the main paper

Conclusions : RANKL blockade alleviates peri-impla...

In summary, the present study suggests that anti-inflammatory miR-146a enhance anti-RANKL-induced inhibition of peri-implant bone resorption through the regulation of TLR2/4 signaling and inhibition of TNF-α expression. Combination of regimens antagonizing both osteoclastogenesis and inflammation may become a more effective strategy to ameliorate peri-implantitis bone loss.

Discussion : RANKL blockade alleviates peri-implan...

According to the previous studies, miR-146a was regulated by NF-κB and blockade of miR-146a could decrease TLR4 and NF-κB in human cells [41, 42], suggesting that miR-146a is involved in TLR/NF-κB signaling pathway. Our recent study showed that miR-146a inhibited inflammatory cytokine secretion in B cells after challenged with P. gingivalis LPS and decreased bone resorption in experimental peri...

Discussion : RANKL blockade alleviates peri-implan...

Our present study showed that anti-RANKL antibody can significantly inhibit the bone loss in peri-implantitis and additional miR-146a treatment will enhance this inhibition through its anti-inflammation effects via TLR2/4 signaling. This is the first report in a murine model of peri-implantitis to demonstrate that anti-RANKL antibody and miR-146a together can significantly reduce bone resorption a...

Results : RANKL blockade alleviates peri-implant b...

In both WT mice and TLR2/4 KO mice, a significantly higher number of inflammatory cells were found infiltrating around the peri-implant tissues in the ligation group compared with the non-ligation group (Fig. 4a–c). However, the number of inflammatory cells in tissues of the ligation group was not significantly changed when treated with anti-RANKL antibody alone in both WT and TLR2/4 KO mice com...

Results : RANKL blockade alleviates peri-implant b...

In our ligature-induced experimental peri-implantitis mouse model, teeth extraction, implant placement, ligation placement, and gingival injection will be performed in a 12-week process (Fig. 1). 86.67% (52 out of 60) of implants in TLR2/4 KO mice achieved osteointegration (no mobility when touched by needles, no obvious bleeding upon probing) after being placed for 4 weeks, which has no signifi...

Methods : RANKL blockade alleviates peri-implant b...

Palatal gingival tissues were isolated from around ligatured implants and were homogenized in lysis buffer using a tissue homogenizer. Total RNA was extracted using PureLink® RNA Mini Kit (Ambion). cDNA was synthesized using the SuperScript III Reversed Transcriptase kit (Invitrogen) according to the manufacturer’s protocol. The mRNA expression of TNF-α and RANKL in gingival was determined by ...

Methods : RANKL blockade alleviates peri-implant b...

The ligations were maintained for 2 weeks, and after which the mice were euthanized by CO2 inhalation and the maxilla were harvested. The gingival tissues of half group of mice were isolated and collected for mRNA expression study. The skulls left were defleshed by beetles for 1 week. Briefly, in beetle’s chamber, freshly dissected skull was put in a paper cup with 0.5 cm diameter holes at...

Methods : RANKL blockade alleviates peri-implant b...

Wild-type (WT) C57BL/6 and TLR2 KO and TLR4 KO mice in C57/BL6 background were purchased from the Jackson Laboratory (Bar Harbor, ME). TLR2 and TLR4 double KO mice (TLR2/4 KO) were crossbreed from TLR2 KO and TLR4 KO mice and confirmed by genotyping. All the animal-associated protocols were reviewed and approved (#17-022) by the Institutional Animal Care and Use Committee of the Forsyth Institute....

Background : RANKL blockade alleviates peri-implan...

Toll-like receptors (TLR) are a family of well-characterized pattern recognition receptors (PRRs) and play an important role in the induction of pro-inflammatory cytokines by recognizing the signature molecules of the host innate immunity [25,26,27]. Our previous studies showed that TLR2 are associated with implant bone loss in a mouse model of peri-implantitis [5] and TLR4 is essential for period...

Background : RANKL blockade alleviates peri-implan...

Dental implant has become a preferable choice to restore the missing tooth in the past few decades for functional and esthetic purposes [1]. However, peri-implantitis has become prevalent accompanying the exponential growth of dental implant procedures [2, 3]. Peri-implantitis is indicated by infection of implant surrounding soft tissues and bone loss, resulting in implant failure eventually [4,5,...

Abstract : RANKL blockade alleviates peri-implant ...

This study suggests that anti-inflammatory miR-146a enhance anti-RANKL-induced inhibition of peri-implant bone resorption through the regulation of TLR2/4 signaling and inhibition of TNF-α expression.

Abstract : RANKL blockade alleviates peri-implant ...

The present study was to determine the effect of local anti-RANKL antibody administration in the presence or absence of microRNA-146a on ligature-induced peri-implant bone resorption, and the potential role of TLR2/4 signaling in such effect. Titanium implants were placed in the left maxilla alveolar bone 6 weeks after extraction of first and second molars in C57/BL6 wild-type (WT) and TLR2−/...

Fig. 6. Comparison of cleansability of each decont...

Fig. 6. Comparison of cleansability of each decontamination method on the different implant surfaces. Asterisk indicates p < 0.05 Fig. 6. Comparison of cleansability of each decontamination method on the different implant surfaces. Asterisk indicates p < 0.05

Fig. 5. Quantitative analysis of CFU counts on rou...

Fig. 5. Quantitative analysis of CFU counts on rough and machined surface implants after cleansing by each method. Asterisk represents vs Cont; a, vs G; b, vs US; c, vs Air; d, vs Rot; e, vs Las which indicates p < 0.05 Fig. 5. Quantitative analysis of CFU counts on rough and machined surface implants after cleansing by each method. Asterisk represents vs Cont; a, vs G; b, vs US; c, vs Air; d...

Fig. 4. SEM analysis of 4 areas. 1 Rough surface...

Fig. 4. SEM analysis of 4 areas. 1 Rough surface—microthread area. 2 Rough surface—macrothread area. 3 Machined surface—microthread area. 4 Machined surface—macrothread area Fig. 4. SEM analysis of 4 areas. 1 Rough surface—microthread area. 2 Rough surface—macrothread area. 3 Machined surface—microthread area. 4 Machined surface—macrothread area

Fig. 3. Decontamination methods. a Gauze soaked in...

Fig. 3. Decontamination methods. a Gauze soaked in saline applied using a sawing motion. b Ultrasonic scaler (SUPRASSON P-MAX, Satelec-Acteon group, Bordeaux, France, power setting: P5, tip: Implant Protect IP3L/R). c Air abrasives (AIR-FLOW MASTER PIEZON®, EMS, Nyon, Switzerland, power setting: water flow 100%, air pressure 75%, powder: AIR-FLOW® PERIO POWDER, nozzle: PERIO-FLOW® nozzles, di...

Fig. 2. GC Aadva® implant; 3.3-mm diameter, 8-mm ...

Fig. 2. GC Aadva® implant; 3.3-mm diameter, 8-mm length Fig. 2. GC Aadva® implant; 3.3-mm diameter, 8-mm length

Fig. 1. Hard resin splint model carrying 6 implant...

Fig. 1. Hard resin splint model carrying 6 implants Fig. 1. Hard resin splint model carrying 6 implants

Table 3 Quantitative analysis of CFU counts (× 10...

Rough surfaceContGUSAirRotLasMedian137.53.446.513.04.816.3Min73.00.36.80.50.63.0Max785.027.0240.035.537.034.0Machine surfaceContGUSAirRotLasMedian84.50.98.53.23.325.3Min43.00.20.92.01.60.4Max295.04.236.014.05.661.5Table 3 Quantitative analysis of CFU counts (× 105) from rough and machined surface implants after cleansing by each method

Table 2 Qualitative evaluation by SEM analysis of ...

Machined surface (microthread)No effectFairGoodExcellentG   +US  + Air  + Rot   +Las +  Machined surface (macrothread)No effectFairGoodExcellentG   +US  + Air  + Rot   +Las  + Table 2 Qualitative evaluation by SEM analysis of micro- and macrothread areas of machined surface implants

Table 1 Qualitative evaluation by SEM analysis of ...

Rough surface (microthread)No effectFairGoodExcellentG  + US +  Air +  Rot  + Las+   Rough surface (macrothread)No effectFairGoodExcellentG  + US  + Air  + Rot  + Las+   Table 1 Qualitative evaluation by SEM analysis of micro- and macrothread areas of rough surface implants

Conclusion : Three-dimensional finite element anal...

Within the limitations of this study, the following conclusions were drawn. The stress distribution in the cortical bone and implant body was smaller in the TL implant than in the BL implant. The TiZr alloy had a lower elastic modulus than cpTi, and the stress distribution generated in the cortical bone and implant body was also lower. The stress distribution generated in the cortical bone and ...

Discussion : Three-dimensional finite element anal...

Clinically, it is generally considered that the crown length increases proportionally when the length of the implant body decreases because of alveolar bone resorption. However, most previous studies performing FEA of short implants have analyzed them with a standard crown length [38]. In this study, the distance from the tip of the implant body to the occlusal plane was standardized to make the a...

Discussion : Three-dimensional finite element anal...

The difference in the implant body structure between the submerged and non-submerged implants greatly affected the stress distribution. Since the TL implant body lies above the bone level rather than level with the crestal bone, it was found that the stress concentrates above the apex of the alveolar bone, regardless of the material type. As a result, the maximum stress value in the cortical bone ...

Discussion : Three-dimensional finite element anal...

Overloading, which is one of the factors contributing to bone resorption around an implant body, can lead to complications because force is applied beyond the prosthodontic or biological tolerance [23]. It is believed that when stress of a certain magnitude is applied to the bone, microscopic bone destruction occurs resulting in bone resorption [24, 25]. Because implants do not have buffering mech...

Results : Three-dimensional finite element analysi...

The distribution of the maximum principal stress in the cortical bone concentrated on the neck of the implant body. In the TL implants, tensile stress was concentrated on the buccal side and compressive stress on the lingual side. In the BL implants, tensile stress concentration was observed on the lingual side. The distributions were similar between the cpTi and TiZr implants (Figs. 4 and 5). Th...

Materials and methods : Three-dimensional finite e...

To validate the accuracy of the FEA model, microstrain of the surrounding bone were compared with the results of in vitro experiment measured with strain gauge [22]. In the literature, it was reported that microstrain of 59.3876 ± 24.7185 μe at the neck of implant and 17.3456 ± 12.9147 μe at the apical occurred in a bovine bone under an oblique load of 120 N. Under the same conditi...

Materials and methods : Three-dimensional finite e...

TL and BL three-dimensional computer-aided design (CAD) implant models were created using the CAD function in computer-aided engineering software (SolidWorks 2014, Dassault Systèmes SolidWorks Corporation, MA, USA), and they were created with reference to conical connection implant used clinically. The connection part of superstructure has a tapered 15° conical shape without any special locking ...

Summary : Three-dimensional finite element analysi...

Dental implants are widely used as a treatment option to replace a defective prosthesis. In recent years, treatment using short implants, which are ≤ 8 mm in length, has been increasing in cases with vertical bone resorption [1]. It is thought that this will become more popular as the number of patients who require minimally invasive treatment, such as older patients and those with chronic d...

Abstract : Three-dimensional finite element analys...

When using short implants, fracture of the implant body and bone resorption are a concern because stress concentrates on and around a short implant. The purpose of this research is to investigate the differences in stress distribution between tissue level (TL) and bone level (BL) implant body designs, and between commercially pure titanium (cpTi) and the newer titanium–zirconium (TiZr) alloy in ...

Table 5 Summary of OHIP-14 (N = 44 and respons...

OHIP domainMinimumMaximumMeanSDFunctional limitation072.341.70Physical pain071.161.51Psychological discomfort081.642.27Physical disability080.751.77Psychological disability081.182.11Social disability080.611.40Handicap080.701.71Total0648.49.7Table 5 Summary of OHIP-14 (N = 44 and response range 0–8)

Table 4 Correlation analyses : Patient experience ...

Outcome variablesCorrelationsSpearman’s rhoP valueOHRQoLOral health compared0.596

Table 3 Patient-reported outcomes : Patient experi...

QuestionResponseFrequencyOral healthVery good/good81.8%Quality of LifeVery good/good90.9%General healthVery good/good81.8%Pain after hip operationExcessive35.0%Satisfaction hip operationVery85.7%Post op infection in hip siteNo95.3%Visible scar on hipYes48.8%Acceptable scarYes20 of 21aReduced sensibility on hip siteNo86.0%Problem walkingNo92.9%Augmented bone block still presentNo6.8%New augmentatio...

Table 2 Patients’ demographic and lifestyle-rela...

VariableFrequencyN or Mean ± SD%Patients Female2454.5 Male2045.5Age (years)61.16 ± 13.10 Age at operation53.73 ± 13.07 Time from augmentation to completing questionnaire (months)93.55 ± 31.75 Civil status Married3068.2 Single1125.0 Widow(er)36.8Housing Alone1227.3 With another person2352.3 > two persons920.5Education Up to primary711.3 Up to secondary23...

Table 1 Summary of questions : Patient experience ...

CategoryResponseQuestion (1) Perceived health-status  General health“Very good” to “bad”  Oral health“Very good” to “bad”  Overall quality of life“Excellent” to “bad” (2) Lifestyle-related  Smoking“Yes,” “no,” or “sometimes”  Appetite“Good” to “bad” (3) Donor site-related  Pain“Yes” and “no”  Infection“Yes” a...

About this article : Patient experience following ...

Gjerde, C.G., Shanbhag, S., Neppelberg, E. et al. Patient experience following iliac crest-derived alveolar bone grafting and implant placement. Int J Implant Dent 6, 4 (2020). https://doi.org/10.1186/s40729-019-0200-8 Download citation Received: 10 October 2019 Accepted: 11 December 2019 Published: 05 February 2020 DOI: https://doi.org/10.1186/s40729-019-0200-8

Rights and permissions : Patient experience follow...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were ...

Supplementary information : Patient experience fol...

A self-administered questionnaire.

Additional information : Patient experience follow...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Patient experience following...

The Ethics Committee was contacted in 2015, and no ethical approval was needed since this was then considered a quality control study. Written consent was obtained from all participants. Not applicable. Cecilie G Gjerde, Siddharth Shanbhag, Evelyn Neppelberg, Kamal Mustafa, and Harald Gjengedal declare that they have no competing interests.

Author information : Patient experience following ...

Correspondence to Cecilie G. Gjerde.

Author information : Patient experience following ...

Department of Oral and Maxillofacial Surgery, Institute of Clinical Dentistry, University of Bergen, Årstadveien 19, 5009, Bergen, Norway Cecilie G. Gjerde & Evelyn Neppelberg Centre for Clinical Dental Research, Institute of Clinical Dentistry, University of Bergen, Bergen, Norway Cecilie G. Gjerde, Siddharth Shanbhag & Kamal Mustafa Department of Oral and Maxillofacial Surgery, Head an...

Funding : Patient experience following iliac crest...

This work was partially funded by the Research Council of Norway through the BEHANDLING project (grant no. 273551) and TROND MOHN Foundation, Norway (BFS2018TMT10).

Acknowledgements : Patient experience following il...

The staff and surgeons at the Department of Oral and Maxillofacial Surgery, Head and Neck Clinic, Haukeland University Hospital, Bergen. Randi Aursland, master student, who helped collecting data. The patients included in this study.

References : Patient experience following iliac cr...

Landes CA, Bundgen L, Laudemann K, Ghanaati S, Sader R. Patient satisfaction after prosthetic rehabilitation of bone-grafted alveolar clefts with nonsubmerged ITI Straumann dental implants loaded at three months. Cleft Palate Craniofac J. 2012;49(5):601–8. Reisine S, Freilich M, Ortiz D, Pendrys D, Shafer D, Taxel P. Quality of life improves among post-menopausal women who received bone augment...

References : Patient experience following iliac cr...

Locker D, Allen F. What do measures of ‘oral health-related quality of life’ measure? Community Dent Oral Epidemiol. 2007;35(6):401–11. Sischo L, Broder HL. Oral health-related quality of life: what, why, how, and future implications. J Dent Res. 2011;90(11):1264–70. Slade GD. Assessing change in quality of life using the Oral Health Impact Profile. Community Dent Oral Epidemiol. 1998;26...

References : Patient experience following iliac cr...

Hill NM, Horne JG, Devane PA. Donor site morbidity in the iliac crest bone graft. Aust N Z J Surg. 1999;69(10):726–8. Finkemeier CG. Bone-grafting and bone-graft substitutes. J Bone Joint Surg Am. 2002;84-A(3):454–64. Hernigou P, Desroches A, Queinnec S, Flouzat Lachaniette CH, Poignard A, Allain J, et al. Morbidity of graft harvesting versus bone marrow aspiration in cell regenerative thera...

References : Patient experience following iliac cr...

Schaaf H, Lendeckel S, Howaldt HP, Streckbein P. Donor site morbidity after bone harvesting from the anterior iliac crest. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109(1):52–8. Sakkas A, Wilde F, Heufelder M, Winter K, Schramm A. Autogenous bone grafts in oral implantology-is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J I...

Abbreviations : Patient experience following iliac...

Health-related quality of life Oral Health Impact Profile-14 Oral health-related quality of life Patient-reported outcome measures Quality of life

Availability of data and materials : Patient exper...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Patient experience following iliac c...

Favorable OHRQoL and satisfaction were reported after advanced reconstruction with iliac crest-derived grafts and implant treatment in orally compromised patients. However, this treatment requires substantial resources including hospitalization and sick leave.

Discussion : Patient experience following iliac cr...

Patients in our study reported satisfaction with the augmentation and implant installation, and as these patients were orally compromised before the operation, their satisfaction with getting fixed teeth most likely improved their perceived oral health condition. This might also, in part, explain why they reported good OHRQoL. Thus, our findings indicate that a majority of patients tolerate the au...

Discussion : Patient experience following iliac cr...

An important finding in this study is that a majority of patients were very satisfied after iliac crest-derived alveolar bone grafting and implant therapy. Although 90% of the patients in our study had successful bone grafting, only 70.1% reported implant survival together with prosthetic rehabilitation after 1 year. These figures are lower than those reported in previous studies [2, 3, 9]. A rev...

Results : Patient experience following iliac crest...

The correlation analyses performed did not show a significant correlation between the complications at the donor site and implant loss (Table 4). The mean OHIP-14 score (Table 5) was 8.4 ± 9.7 (range 0–56) in 44 patients of whom 35 patients scored 14 or less. Nine patients scored a total sum of 1 [1], i.e. “hardly ever” impact on any single item and “at no time” on the remaining ...

Results : Patient experience following iliac crest...

The final sample consisted of 44 patients that responded and completed the questionnaire, giving a response rate of 74.6%: 24 women and 20 men, mean age of 61.2 years ± 13.1 (range 27–82 years). The mean time from augmentation surgery until completing the questionnaire was 7.8 years ± 2.65 (range 1.9–12 years). Summary of demographic and lifestyle-related data is presented (Tabl...

Methods : Patient experience following iliac crest...

Implants were placed 4–6 months after the grafting procedure. The implant installations were performed by different oral surgeons (not in the hospital) and different implant systems were used. The implants installed into the augmented bone were allowed to heal for an additional 4–6 months before loading. The records of the original 69 patients were examined with regard to (1) grafting sit...

Methods : Patient experience following iliac crest...

This cross-sectional retrospective cohort study was based on records from all patients (n = 69) who underwent advanced alveolar augmentation with autologous iliac bone grafts at the Department of Oral and Maxillofacial Surgery, Haukeland University Hospital, Bergen, Norway, over 10 years (2002–2012). These patients were orally compromised with severe chewing problems as well as speech diff...

Background : Patient experience following iliac cr...

Health-related QoL (HRQoL) is a dynamic concept referring to an individual’s subjective assessment and perspective of current general health condition as well as functional, social, and emotional well-being [23, 24]. Most people regard oral health as important for QoL, and this is mediated through the concept of oral health-related QoL (OHRQoL) [25]. In this regard, OHRQoL is an important PROM i...

Background : Patient experience following iliac cr...

Insufficient alveolar bone volume, as a result of periodontal disease, trauma, congenital anomalies and/or resorption atrophy, often presents a clinical challenge for optimal placement of dental implants for prosthetic rehabilitation. In such cases, augmentation of alveolar bone, with either autologous bone, allogeneic, xenogeneic, or alloplastic biomaterials, is a prerequisite for placing implant...

Abstract : Patient experience following iliac cres...

The objective of this study was to assess patient-reported outcomes such as satisfaction and quality of life after advanced alveolar bone augmentation with anterior iliac crest grafting and implant treatment in orally compromised patients. This cross-sectional retrospective cohort study included 59 patients (29 women and 30 men) with major functional problems, who underwent advanced alveolar augm...

Fig. 2. Intraoral radiograph of an immediately pla...

Fig. 2. Intraoral radiograph of an immediately placed post-extractive dental implant with a full contour zirconia restoration after 1 year (same patient as in Fig. 1) Fig. 2. Intraoral radiograph of an immediately placed post-extractive dental implant with a full contour zirconia restoration after 1 year (same patient as in Fig. 1)

Fig. 1. Pre-operative panoramic radiograph of a fa...

Fig. 1. Pre-operative panoramic radiograph of a failing molar in position 36 Fig. 1. Pre-operative panoramic radiograph of a failing molar in position 36

Table 5 Patient’s satisfaction 12 months (T12)...

 Agreement percentage (n = 11)Presence of shame0.0Self-confidence has decreased0.0Evades eating with the implant9.1The ability to chew has decreased0.0Implant influences speech0.0Implant influences taste0.0Not satisfied with the colour of the crown0.0Not satisfied with the form of the crown0.0Not satisfied with the colour of the mucosa around the crown0.0Not satisfied with the form of the muc...

Table 4 Mean value, standard deviation, and freque...

Bone change (mm)n = 11mean (SD)− 0.17 mm (0.73)> − 2.0 to − 1.51 (9.1)> − 1.5 to − 1.00 (0.0)> − 1.0 to − 0.52 (18.2)> − 0.5 to 0.04 (36.4)> 0.0 to 0.52 (18.2)> 0.5 to 1.02 (18.2)Table 4 Mean value, standard deviation, and frequency distribution (percentages) of marginal bone change between 1 month after restoration placement (T1) and 1 year in ...

Table 3 Mean value, standard deviation, and freque...

Bone level (mm)n = 15Mean (SD)− 0.94 mm (0.54)> − 2.5 to − 2.01 (6.7)> − 2.0 to − 1.52 (13.3)> − 1.5 to − 1.04 (26.7)> − 1.0 to − 0.55 (33.3)> − 0.5 to 0.03 (20.0)Table 3 Mean value, standard deviation, and frequency distribution (percentages) of marginal bone level at 1 month after restoration placement (T1)

Table 2 Frequencies and percentages of plaque inde...

 T1 (n = 15)T12 (n = 11)Plaque indexScore 0, 15 (100%)Score 0, 11 (100%)Calculus indexScore 0, 15 (100%)Score 0, 11 (100%)Gingival indexScore 0, 15 (100%)Score 0, 11 (100%)Bleeding indexScore 0, 15 (100%)Score 0, 10 (91%)Score 1, 1 (9%)Probing depth in mm (sd)2.0 (0.9)1.9 (0.8)Table 2 Frequencies and percentages of plaque index scores (possible score 0–3), calculus index scores (possibl...

Table 1 Baseline characteristics of the study grou...

Mean age in years (sd, minimum-maximum)57 (6.6, 44–67)Gender (number male/female)6/9Reason of failure (severe caries/crown fracture/root fracture)3/6/6Implant position (maxilla/mandible)7/8Implant position (in between teeth/no tooth distally)11/4Table 1 Baseline characteristics of the study group

About this article : Immediate implant placement i...

Meijer, H.J.A., Raghoebar, G.M. Immediate implant placement in molar extraction sites: a 1-year prospective case series pilot study. Int J Implant Dent 6, 3 (2020). https://doi.org/10.1186/s40729-019-0201-7 Download citation Received: 29 October 2019 Accepted: 11 December 2019 Published: 12 February 2020 DOI: https://doi.org/10.1186/s40729-019-0201-7

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

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Ethics declarations : Immediate implant placement ...

This clinical study was conducted in accordance with the World Medical Association Declaration of Helsinki (version VI, 2002). The Medical Ethical Committee of the University Medical Center Groningen considered this case series study not subject to the Medical Research Involving Human Subjects Act (Number M15.184100). The study was registered at the Netherlands Trial Register (Number NL8117). Afte...

Author information : Immediate implant placement i...

Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, PO Box 30.001, NL-9700 RB, Groningen, The Netherlands Henny J. A. Meijer & Gerry M. Raghoebar Department of Implant Dentistry, University Medical Center Groningen, Groningen, The Netherlands Henny J. A. Meijer You can also search for this author in PubMed Google Scholar You can also search for this author in...

Funding : Immediate implant placement in molar ext...

An unrestricted grant from Nobel Biocare Services AG funded the 1-year clinical study; implant materials were provided (study code: 2015-1365).

Acknowledgements : Immediate implant placement in ...

Not applicable.

References : Immediate implant placement in molar ...

Tallarico M, Xhanari E, Pisano M, Gatti F, Meloni SM. Molar replacement with 7 mm-wide diameter implants: to place the implant immediately or to wait 4 months after socket preservation? 1 year after loading results from a randomised controlled trial. Eur J Oral Implantol. 2017;10:169–78. Checchi V, Felice P, Zucchelli G, Barausse C, Piattelli M, Pistilli R, Grandi G, Esposito M. Wide diameter i...

References : Immediate implant placement in molar ...

Hamouda NI, Mourad SI, El-Kenawy MH, Maria OM. Immediate implant placement into fresh extraction socket in the mandibular molar sites: a preliminary study of a modified insertion technique. Clin Implant Dent Relat Res. 2015;17(Suppl 1):e107–16. https://doi.org/10.1111/cid.12135. Demircan S, Çankaya AB. Is immediate implant placement possible in the maxillary molar area? An anatomical study. Qu...

References : Immediate implant placement in molar ...

Gallucci GO, Hamilton A, Zhou W, Buser D, Chen S. Implant placement and loading protocols in partially edentulous patients: a systematic review. Clin Oral Implants Res. 2018;29(Suppl 16):106–34. https://doi.org/10.1111/clr.13276. Slagter KW, Den Hartog L, Bakker NA, Vissink A, Meijer HJA, Raghoebar GM. Immediate placement of dental implants in the esthetic zone: a systematic review and pooled a...

Availability of data and materials : Immediate imp...

The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.

Conclusion : Immediate implant placement in molar ...

Within the limitations of this study, it has been demonstrated that immediate placement of regular diameter implants in molar post-extraction sites of maxilla and mandible resulted in a high implant failure rate during a 1-year follow-up period.

Discussion : Immediate implant placement in molar ...

In an attempt to incorporate the concept of patient engagement, this study investigated the patients’ satisfaction with the rehabilitated posterior region by assessing specific patient-centred outcomes. This was done by the patients filling out the established questionnaire 1 year after restoration placement [26, 27]. All the questioned outcome measures showed high patient satisfaction which is...

Discussion : Immediate implant placement in molar ...

The mean marginal bone level was 0.94 mm below the neck of the implant at 1 month after restoration placement (T1). The optimal position of the peri-implant bone after a maturation period should be at the same level as the neck of the implant. This means that part of the biological width of the present study, which is acting as a barrier, was in contact with the implant surface roughness and w...

Discussion : Immediate implant placement in molar ...

Immediate placement of regular diameter implants in molar post-extraction sites of the maxilla and mandible resulted in a high implant failure rate during a 1-year follow-up period. The implant survival rate was 73.3% after 1 year in function. The performance of immediate placements in post-extraction sites was also analysed in the Cafiero et al., Atieh et al., Tallarico et al., and Checchi et a...

Results : Immediate implant placement in molar ext...

All 15 consecutive patients eligible to join the study on the basis of the inclusion and exclusion criteria agreed to participate in this study. The patient characteristics are depicted in Table 1. All implant-supported restorations had natural antagonistic teeth. Four of the 15 patients treated had a mobile implant, which had to be removed (in two patients 3 months after crown placement and in...

Materials and methods : Immediate implant placemen...

Radiographs were taken and evaluated 1 month and 12 months after restoration placement using a parallel technique, with an X-ray holder for periapical radiographs. They were analysed using a specially designed computer software to perform linear measurements on digital radiographs. The calibration was carried out in the vertical plane of each radiograph by using the known distance of the implan...

Materials and methods : Immediate implant placemen...

An impression was made at implant level 2 weeks after the second stage of the surgery in order to fabricate a single crown. A definitive full-zirconia crown (yttria-stabilized zirconium oxide) with an angulated screw channel (NobelProcera FCZ Implant Crown, NobelBiocare AB) was manufactured in the determined colour at a centralized milling facility (NobelProcera Service Center, Mahwah, NJ, USA) a...

Materials and methods : Immediate implant placemen...

All patients referred to the Department of Oral and Maxillofacial Surgery (University of Groningen, University Medical Hospital), from January 2016 to July 2017, for single-tooth implant therapy in the maxillary and mandibular posterior region were considered for inclusion. The following inclusion criteria were applied: One failing first or second molar in the maxilla or mandible; Sufficient bon...

Background : Immediate implant placement in molar ...

Implant placement and loading protocols are changing [1]. There is a growing tendency to place single tooth implants immediately after the extraction of a failing tooth, especially in the maxillary aesthetic region, and preferably combined with immediate provisionalization [2,3,4,5,6]. This tendency is related to evolving society factors, including more demanding patients and a wish for direct tre...

Abstract : Immediate implant placement in molar ex...

There is a growing tendency to place single tooth implants immediately after extracting a failing tooth in the posterior region. The aim of this prospective case series pilot study was to evaluate immediate implant placement in molar post-extraction sites during a 1-year follow-up period. Fifteen consecutive patients with a single failing molar in the maxilla or mandible, and presenting enough bo...

Fig. 6. Optic microscope photo (× 9 magnification...

Fig. 6. Optic microscope photo (× 9 magnification) after 30 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant (group A). Right side: laser-treated implant Fig. 6. Optic microscope photo (× 9 magnification) after 30 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant ...

Fig. 5. Optic microscope photo (× 9 magnification...

Fig. 5. Optic microscope photo (× 9 magnification) after 15 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant (group A). Right side: laser-treated implant Fig. 5. Optic microscope photo (× 9 magnification) after 15 days of implantation. Left side: machined implant (group C). Central photo: sandblasted and acid-etched implant ...

Fig. 4. Exemplificative photo of implant placement...

Fig. 4. Exemplificative photo of implant placement in sheep iliac crest (left side). All implant groups were inserted in the same bone host Fig. 4. Exemplificative photo of implant placement in sheep iliac crest (left side). All implant groups were inserted in the same bone host

Fig. 3. Scanning electron microscopy picture of gr...

Fig. 3. Scanning electron microscopy picture of group C implant surface Fig. 3. Scanning electron microscopy picture of group C implant surface

Fig. 2. Scanning electron microscopy picture of gr...

Fig. 2. Scanning electron microscopy picture of group B implant surface Fig. 2. Scanning electron microscopy picture of group B implant surface

Fig. 1. Scanning electron microscopy picture of gr...

Fig. 1. Scanning electron microscopy picture of group A implant surface Fig. 1. Scanning electron microscopy picture of group A implant surface

Table 3 Mean BIC% value of each group after 30 d...

GroupBIC% (mean ± SD)A50.31 ± 13.44B56.53 ± 13.62C20.54 ± 11.06Table 3 Mean BIC% value of each group after 30 days of healing

Table 2 Mean BIC% value of each group after 15 d...

Group BIC% (mean ± SD) A 39.08 ± 15.85 B 37.35 ± 15.76 C 25.28 ± 8.97   Table 2 Mean BIC% value of each group after 15 days of healing

Table 1 Implants details of both groups: screw pit...

 Group A implantsGroup B implantsGroup C implantsScrew pitch1.25 mm0.6 mm0.6 mmSmooth neck2.8 mm0.25 mm0.25 mmSurface treatmentLarge grit-blasted and acid-etched SLA surface, processed to a high degree of hydrophilicity (SLActive®)Laser surface characterized by a series of 20 μm diameter holes (7–10 μm deep) every 10 μm (Syntegra®)Machined surfaceSurface roughness (Ra)1.5...

About this article : Comparative evaluation among ...

De Tullio, I., Berardini, M., Di Iorio, D. et al. Comparative evaluation among laser-treated, machined, and sandblasted/acid-etched implant surfaces: an in vivo histologic analysis on sheep. Int J Implant Dent 6, 7 (2020). https://doi.org/10.1186/s40729-019-0204-4 Download citation Received: 30 August 2019 Accepted: 24 December 2019 Published: 19 February 2020 DOI: https:...

Rights and permissions : Comparative evaluation am...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Comparative evaluation am...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Comparative evaluation among...

The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol, according to the guidelines established by the European Union Council Directive of February 2013 (R.D.53/2013) (protocol number 3809). The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the st...

Author information : Comparative evaluation among ...

Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy I. De Tullio, F. Perfetti & G. Perfetti Pescara, Italy M. Berardini Foggia, Italy D. Di Iorio You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You c...

Funding : Comparative evaluation among laser-treat...

No grants were received for the present study.

Acknowledgements : Comparative evaluation among la...

The authors wish to thank the company Geass s.r.l. for providing implants used in the present study.

References : Comparative evaluation among laser-tr...

Piattelli A, Manzon L, Scarano A, Paolantonio M, Piattelli M. Histologic and histomorphometric analysis of the bone response to machined and sandblasted titanium implants: an experimental study in rabbits. Int J Oral Maxillofac Implants. 1998;13:805–10. Lee JT, Cho SA. Biomechanical evaluation of laser-etched Ti implant surfaces vs. chemically modified SLA Ti implant surfaces: Removal torque an...

References : Comparative evaluation among laser-tr...

Gaggl A, Schultes G, Muller WD, Karcher H. Scanning electron microscopical analysis of laser-treated titanium implant surfaces. A comparative study. Biomaterials. 2000;21(10):1067–73. Bonsignore LA, Colbrunn RW, Tatro JM, Messerschmitt PJ, Hernandez CJ, Goldberg VM, Stewart MC, Greenfield EM. Surface contaminants inhibit osseointegration in a novel murine model. Bone. 2011;49(5):923–30. Peng...

References : Comparative evaluation among laser-tr...

Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52(2):155–70. Puleo DA, Nanci A. Understanding and controlling the bone-implant interface. Biomaterials. 1999;20(23-24):2311–21. Huang MS, Chen LK, Ou KL, et al. Rapid osseointegration of titanium...

Availability of data and materials : Comparative e...

All data and materials are available at University Chieti-Pescara, Department of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.

Conclusions : Comparative evaluation among laser-t...

Results from the present in vivo analysis revealed that both sandblasted and acid-etched titanium implants and laser-treated titanium implants, compared to the machined ones, have higher values of osseointegration in less healing time. Indeed, both groups A and B at 15 days had higher values of the BIC% if compared to group C and were able to significantly increase their BIC% in the passage fro...

Discussion : Comparative evaluation among laser-tr...

Data showed by the present study suggest that laser and sandblasted and acid-etched surface treatments could enhance the osteogenic bone formation by “contact,” already observed by other authors [20, 21]. Another interesting emerging datum is the observation of BIC% changes between 15 and 30 days: it is possible to assume that between the fifteenth and the thirtieth day, most part of the pe...

Discussion : Comparative evaluation among laser-tr...

In the present study, the iliac crest of the sheep was chosen as a model because the site is characterized by a cancellous bone rich in marrow spaces, similar for quality to D4 density. This bone model appears superimposable to postero-lateral sectors of the human upper jaw that often represents a hard challenge for implant osseointegration due to low bone density. Bone quality, in fact, is a key...

Results : Comparative evaluation among laser-treat...

All implants resulted clinically integrated and stable into the bone tissue. No signs of tissue inflammation or infection were detected. At low magnification, all the samples appeared surrounded by new tissue. The distinction between native tissue and newly formed bone was not clear, likely due to the fact that the latter is still in an initial forming phase. In the machined samples (group C) bon...

Materials and methods : Comparative evaluation amo...

Measurement of the total length of the left half of the fixture; Measurement of the contact area between bone and implant in the left half of the fixture; Measurement of the total length of the right half of the fixture; and Measurement of the contact area between bone and implant in the right half of the fixture. Afterwards, the sum of parameters A and C represented the total length of the wh...

Materials and methods : Comparative evaluation amo...

Implant drilling procedures were carried out using the drill sequence recommended by the manufacturer. The drill speed was set at 700 rpm under continuous sterile saline solution irrigation (stored at + 4 °C). Implants were inserted with an insertion torque peak between 28 and 34 Ncm. Each animal received three implants of each group. The suture of deep muscle planes was performed with poly...

Materials and methods : Comparative evaluation amo...

The Ethics Committee for Animal Research of the Veterinary School of the University of Teramo (Teramo, Italy) approved the study protocol, which followed guidelines established by the European Union Council Directive of February 2013 (R.D.53/2013). A total of 36 implants were used in the present study. Implants had different macro-geometries and surfaces and they were divided into three groups of...

Introduction : Comparative evaluation among laser-...

In addition, some animal studies [15, 16] found an increased removal torque in laser processed implants compared to machined surface implants inserted. The aim of the present paper was to evaluate the osseointegration process, in terms of bone to implant contact percentage (BIC%), of three different implants surface (machined, sandblasted and acid-etched, and laser-treated) both after 15 and 30...

Introduction : Comparative evaluation among laser-...

Dental implant surfaces represent one of the key factors that could influence the osseointegration processes [1]. Puleo et al. [2] confirmed that the surface topography, as well as the chemical nature and the implant macro and micro geometry, is involved in creating a clinical and histological efficient bone-implant interface. It was demonstrated that different superficial treatments could affect ...

Abstract : Comparative evaluation among laser-trea...

The aim of the present in vivo analysis was to evaluate the osseointegration process of titanium implants with three different surfaces (machined, sandblasted and acid-etched, and laser-treated) after 15 and 30 days of healing period. Thirty-six implants with different surfaces were placed in the iliac crest of four Bergamasca sheep. The implant surfaces tested were sandblasted and acid-etched ...

Highlights : Is maxillary diastema an appropriate ...

Current study indicates that maxillary nature diastema could be a site to place implant, but it has a low successful rate. Data indicate that the true success rate of implantation in maxillary natural diastema in rat is less than 38.4% at a confident level of 95%. Therefore, it is not an appropriate site for dental implant experiment. Moreover, it may be able to form certain osseointegration, but ...

Abstract : Is maxillary diastema an appropriate si...

Implantology or implant dentistry is growing fast during last four decades. Facing the growing demand of implant treatment, there are extreme challenges to clinicians and researchers. First is peri-implantitis with remarkable prevalence. Though investigators have revealed that the etiology of the peri-implant infection is similar to periodontitis, clinically there is no effective treatment. Second...

Fig. 9. Scatter diagrams illustrating the distribu...

Fig. 9. Scatter diagrams illustrating the distribution of angle deviation of each protocol. a Anterior implants. b Posterior implants Fig. 9. Scatter diagrams illustrating the distribution of angle deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 8. Box plot diagrams illustrating the distrib...

Fig. 8. Box plot diagrams illustrating the distribution of maximum angle deviation of each protocol. a Anterior implants. b Posterior implants Fig. 8. Box plot diagrams illustrating the distribution of maximum angle deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 7. Scatter diagrams illustrating the distribu...

Fig. 7. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants Fig. 7. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 6. Box plot diagrams illustrating the distrib...

Fig. 6. Box plot diagrams illustrating the distribution of maximum horizontal apex deviation of each protocol. a Anterior implants. b Posterior implants Fig. 6. Box plot diagrams illustrating the distribution of maximum horizontal apex deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 5. Scatter diagrams illustrating the distribu...

Fig. 5. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants Fig. 5. Scatter diagrams illustrating the distribution of horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 4. Box plot diagrams illustrating the distrib...

Fig. 4. Box plot diagrams illustrating the distribution of maximum horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants Fig. 4. Box plot diagrams illustrating the distribution of maximum horizontal neck deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 3. Box plot diagrams illustrating the distrib...

Fig. 3. Box plot diagrams illustrating the distribution of vertical deviation of each protocol. a Anterior implants. b Posterior implants Fig. 3. Box plot diagrams illustrating the distribution of vertical deviation of each protocol. a Anterior implants. b Posterior implants

Fig. 2. a Schematic diagram illustrating the measu...

Fig. 2. a Schematic diagram illustrating the measurement of vertical, horizontal neck, horizontal apex, and angle deviations. b Three forms of horizontal deviation were measured: maximum, mesiodistal, and buccolingual directions Fig. 2. a Schematic diagram illustrating the measurement of vertical, horizontal neck, horizontal apex, and angle deviations. b Three forms of horizontal deviation we...

Fig. 1. Flowchart summarizing the different phases...

Fig. 1. Flowchart summarizing the different phases of the experiment Fig. 1. Flowchart summarizing the different phases of the experiment

Table 1 Summary of implant vertical, horizontal an...

 Vertical implant deviation  Anterior implantPosterior implantp values between anterior and posterior implants FGPGFHFGPGFHMean (mm)0.210.530.300.340.640.49FG = 0.07SD (mm)0.120.520.240.230.370.22PG = 0.27Maximum (mm)0.391.650.810.801.130.80FH = 0.05Minimum (mm)0.090.050.070.040.200.07p valuesAll groups = 0.12All groups = 0.08  Maximum horizontal implant neck deviation ...

About this article : Accuracy of static computer-a...

Abduo, J., Lau, D. Accuracy of static computer-assisted implant placement in anterior and posterior sites by clinicians new to implant dentistry: in vitro comparison of fully guided, pilot-guided, and freehand protocols. Int J Implant Dent 6, 10 (2020). https://doi.org/10.1186/s40729-020-0205-3 Download citation Received: 31 October 2019 Accepted: 21 January 2020 Published: 11 March 2020 DOI:...

Rights and permissions : Accuracy of static comput...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Accuracy of static comput...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Accuracy of static computer-...

This study was approved by the University of Melbourne Human Research Ethics Committee (1851406.1). The study complied with the Declaration of Helsinki. All participants were aware of the nature of the study and provided their consent prior to the commencement of the study. Not applicable Jaafar Abduo, and Douglas Lau declare that they have no competing interests.

Author information : Accuracy of static computer-a...

Associate Professor in Prosthodontics, Convenor of Postgraduate Diploma in Clinical Dentistry (Implants), Melbourne Dental School, Melbourne University, 720 Swanston Street, Melbourne, VIC, 3010, Australia Jaafar Abduo Periodontist, Private Practice, Melbourne University, Melbourne, VIC, Australia Douglas Lau You can also search for this author in PubMed Google Scholar You can also search fo...

Funding : Accuracy of static computer-assisted imp...

The implants, surgical kits, and guide sleeves were provided by Straumann Australia. This study has been funded by the Kernot Early Career Researcher Award. No financial income for conducting the study was received by the authors.

Acknowledgements : Accuracy of static computer-ass...

The authors would also like to thank Mr. Attila Gergely for his technical support in developing the simulated case and the input of the team of Digital Dental Network in designing the guides.

References : Accuracy of static computer-assisted ...

Deeb GR, Allen RK, Hall VP, Whitley D 3rd, Laskin DM, Bencharit S. How accurate are implant surgical guides produced with desktop stereolithographic 3-dimentional printers? J Oral Maxillofac Surgery. 2017;75:2551–9. Horwitz J, Zuabi O, Machtei EE. Accuracy of a computerized tomography-guided template-assisted implant placement system: an in vitro study. Clin Oral Implants Res. 2009;20:1156–62...

References : Accuracy of static computer-assisted ...

Rungcharassaeng K, Caruso JM, Kan JY, Schutyser F, Boumans T. Accuracy of computer-guided surgery: a comparison of operator experience. J Prosthet Dent. 2015;114:407–13. Park SJ, Leesungbok R, Cui T, Lee SW, Ahn SJ. Reliability of a CAD/CAM surgical guide for implant placement: an in vitro comparison of surgeons' experience levels and implant sites. Int J Prosthodont. 2017;30:367–9. Marheine...

References : Accuracy of static computer-assisted ...

Belser UC, Mericske-Stern R, Bernard JP, Taylor TD. Prosthetic management of the partially dentate patient with fixed implant restorations. Clin Oral Implants Res. 2000;11:126–45. Buser D, Martin W, Belser UC. Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants. 2004;19:43–61. Ramaglia L, Toti P, Sbordone...

Abbreviations : Accuracy of static computer-assist...

Three-dimensional Computer-aided design/computer-aided manufacturing Cone beam computed tomography Digital Imaging and Communications in Medicine Fully guided Freehand Pilot-guided Static computer-assisted implant placement Surface tessellation language

Availability of data and materials : Accuracy of s...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Accuracy of static computer-assisted...

Within the limitations of the present study, it can be hypothesized that apart from vertical deviation, the FG protocol is more accurate than the PG and FH protocols for all the evaluated variables in the hands of inexperienced clinicians. The PG and FH protocols were generally similar. The FG protocol did not seem to be influenced by the position of the placed implants, while the PG and FH protoc...

Discussion : Accuracy of static computer-assisted ...

For the majority of the evaluated variables, there was a tendency for the posterior implants to suffer from more deviation than anterior implants. This is in accordance with several published reports [5, 21, 22]. Interestingly, implants placed by the FG protocol seemed to be less vulnerable to inaccuracy by changing the implant sites, while the PG and FH protocols showed more horizontal and angle ...

Discussion : Accuracy of static computer-assisted ...

The superior accuracy and the less variation of the FG protocol is most likely related to the control of all the drilling steps and the implant placement via sequential use of precision sleeves. This eliminated the manual orientation and handling of the drills at any stage of drilling or implant placement. In accordance with these observations, Noharet et al. reported a better accuracy of the FG p...

Discussion : Accuracy of static computer-assisted ...

The overall outcome of this study indicates the superiority of the FG protocol in comparison to PG and FH protocols for placing single implants. With the exception of vertical deviation, this was obvious for horizontal neck, horizontal apex, and angle deviations that were closer to the planned implant for the FG protocol than the other protocols. In addition, this superiority was shown for anterio...

Results : Accuracy of static computer-assisted imp...

In relation to the maximum angle deviation (Fig. 8), the FG protocol had less deviation than the other protocols for anterior (2.42 ± 0.98°) and posterior (2.61 ± 1.23°) implants. The PG (4.65 ± 1.78°) and FH (4.79 ± 2.08°) protocols were similar for anterior implant placement, while the FH protocol seemed more accurate for posterior implants (4.77 ± 2.09°) than the ...

Results : Accuracy of static computer-assisted imp...

In general, for all the variables, there was a tendency for the FG protocol to yield more accurate implant placement than other protocols (Table 1). In relation to vertical deviation, the PG protocol seemed to be associated with more errors. However, there was no significant difference in vertical deviation among all the protocols. Figure 3 indicates that the PG protocol was associated with deep...

Methods : Accuracy of static computer-assisted imp...

The vertical deviation was measured by calculating the discrepancy along the long axis of the planned implant at the center of the platform (Fig. 2a). In addition to the magnitude of the deviation, the direction of the error was determined. The horizontal deviations were measured at the neck and the apex of the planned implant. The angle deviation was computed by measuring the angle of the long a...

Methods : Accuracy of static computer-assisted imp...

For all the protocols, straight bone level Straumann dummy implants were planned. The anterior implants were 4.1 × 10 mm, while the posterior implants were 4.8 × 10 mm. The anterior implants were planned to be placed 2 mm subcrestal, while the posterior implants were planned to be placed 1 mm subcrestal. For the conventional protocols, the clinicians had access to physical intact Ni...

Methods : Accuracy of static computer-assisted imp...

The soft tissue silicone former was removed from the Nissin model to simulate bone anatomy. Subsequently, this model was duplicated with clear resin material mixed with barium sulfate and scanned by a cone beam computed tomography (CBCT) machine to generate cross-sectional DICOM images. The DICOM images were imported to the implant planning software programs. For the FH protocol, the 2D DICOM ima...

Methods : Accuracy of static computer-assisted imp...

A total of 10 qualified clinicians with a minimum of 3 years of general practice experience were invited to participate in the study. The number of participants was similar to previously published studies [12, 19], and was confirmed by sample size calculation. A mean horizontal deviation of 1 mm and an expected standard deviation of 0.75 mm that were reported from earlier studies [13, 19] were ...

Background : Accuracy of static computer-assisted ...

Despite all the advantages of sCAIP protocols, several studies reported that they are still prone to errors and complications [7,8,9, 17, 18]. The FG and PG protocols still require thorough planning and surgical understanding and skills [11]. For multiple implants and long-span edentulous ridges, guided surgery has the advantages of being more reliable, more comfortable for the patient, and more r...

Background : Accuracy of static computer-assisted ...

Implant treatment is a growing field in dentistry, and many clinicians aim to increase their scope of practice by including such treatment. One of the main challenges encountered by clinicians new to implant dentistry is the determination and controlling of implant location. It is the consensus that implant placement must be planned to achieve an acceptable position for an ideal restorative outcom...

Abstract : Accuracy of static computer-assisted im...

One of the challenges encountered by clinicians new to implant dentistry is the determination and controlling of implant location. This study compared the accuracy of fully guided (FG) and pilot-guided (PG) static computer-assisted implant placement (sCAIP) protocols against the conventional freehand (FH) protocol for placing single anterior and posterior implants by recently introduced clinicians...

Fig. 3. Histological magnifications of specimens e...

Fig. 3. Histological magnifications of specimens exposing a significant areas of lamellar bone in-between and parallel to the surface of older trabeculae (accentuated by green overlay), b osteoclastic activity, and c active bone formation at intrabony marginal regions Fig. 3. Histological magnifications of specimens exposing a significant areas of lamellar bone in-between and parallel to the ...

Fig. 2. Histological view (buccal aspect) displayi...

Fig. 2. Histological view (buccal aspect) displaying mean BIC (%) and mean bone density (%) at corresponding regions (500 μm zones) from BD to A. Blue lines along the implant perimeter display BIC presence and yellow lines display BIC absence Fig. 2. Histological view (buccal aspect) displaying mean BIC (%) and mean bone density (%) at corresponding regions (500 μm zones) from BD to A. Blue...

Fig. 1. Histological section illustrating the land...

Fig. 1. Histological section illustrating the landmarks to determine the conducted histomorphometrical length measurements: DL, RB, and BIC at buccal RB. The red square frames the intra-thread area (ROI) for OD and ELD analysis Fig. 1. Histological section illustrating the landmarks to determine the conducted histomorphometrical length measurements: DL, RB, and BIC at buccal RB. The red squar...

Table 3 Mean osteocyte (OD) and empty lacunae dens...

SP ID Mean OD (number/mm2)Mean ELD (number/mm2)Osteocyte/empty lacuna ratio12932311.2622211021.3231122450.4541721021.6851621431.12Mean1921651.17SD ±6869.20.4595% CI(132–251)(103–225) Table 3 Mean osteocyte (OD) and empty lacunae density (ELD) at peri-implant residual bone

Table 2 Results from histomorphometric measurement...

Specimen IDDL (mm)RB (mm)B.Ar/T.Ar (%)BIC (%)14.83.572.480.025.68.992.375.035.65.388.173.843.87.781.868.753.63.292.571.1Mean4.75.785.574.0SD ±1.02.58.04.095% CI3.1–4.93.3–6.878–9270.6–77.6Table 2 Results from histomorphometric measurements exhibiting DL, RB, bone density (%), residual bone-to-implant contact (%) values

Table 1 Patient and implant site characteristics :...

Sample ID Gender Age Location Prosthesis type Loading time (years) lmplant surface Mean BOP (%) Supp (+/−) Mean PD (mm) MBL (mm) 1 M 69 Maxilla Single-screwed 5.1 Machined 100 + 6.4 B: 4.0P: 6.0 2 F 60 Mandible Single-screwed 10.0 Machined 100 − 6.0 B: 4.5L: 5.0 3 F 60 Mandible Single-screwed 10.0 Machined 100 − 6.2 B: 4.0L: 5...

About this article : Histological characteristics ...

Galárraga-Vinueza, M., Tangl, S., Bianchini, M. et al. Histological characteristics of advanced peri-implantitis bone defects in humans. Int J Implant Dent 6, 12 (2020). https://doi.org/10.1186/s40729-020-00208-8 Download citation Received: 08 January 2020 Accepted: 19 February 2020 Published: 25 March 2020 DOI: https://doi.org/10.1186/s40729-020-00208-8

Rights and permissions : Histological characterist...

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Histological characterist...

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Ethics declarations : Histological characteristics...

The study protocol no. 3437751 was approved by the Human Research Committee at Federal University of Santa Catarina-Brazil, 2016–2021, and all patients signed an informed consent according to the university ethics regulations. Not applicable The authors declare that they have no competing of interests.

Author information : Histological characteristics ...

MG, FS, RG, and MB contributed to the design of the study. ST and KO contributed to study selection and data extraction. MG, RM, FS, RG, MB, ST, and KO contributed to the drafting of the paper and revising it critically. All authors read, revised, and approved the final manuscript. Correspondence to Reinhard Gruber.

Author information : Histological characteristics ...

Department of Oral Surgery and Implantology, Carolinum, Goethe University, Frankfurt, Germany Maria Elisa Galárraga-Vinueza, Karina Obreja & Frank Schwarz Post-Graduate Program in Implant Dentistry (PPGO), Federal University of Santa Catarina (UFSC), Florianópolis, SC, Brazil Maria Elisa Galárraga-Vinueza, Marco Bianchini & Ricardo Magini Core Facility Hard Tissue and Biomaterial Rese...

Funding : Histological characteristics of advanced...

The present study was funded by the authors’ own departments.

Acknowledgements : Histological characteristics of...

Not applicable

References : Histological characteristics of advan...

Kohal R-J, Patzelt SBM, Butz F, Sahlin H. One-piece zirconia oral implants: one-year results from a prospective case series. 2. Three-unit fixed dental prosthesis (FDP) reconstruction. J Clin Periodontol [Internet]. 2013 [cited 2018 Nov 15];40(5):553–562. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23506654. Dallas SL, Prideaux M, Bonewald LF. The osteocyte: an endocrine cell ... and mor...

References : Histological characteristics of advan...

Berglundh T, Gislason O, Lekholm U, Sennerby L, Lindhe J. Histopathological observations of human periimplantitis lesions. J Clin Periodontol [Internet]. 2004 [cited 2019 Mar 13];31(5):341–347. Available from: http://doi.wiley.com/10.1111/j.1600-051X.2004.00486.x. Zitzmann NU, Berglundh T, Ericsson I, Lindhe J. Spontaneous progression of experimentally induced periimplantitis. J Clin Periodonto...

References : Histological characteristics of advan...

Schwarz F, Herten M, Sager M, Bieling K, Sculean A, Becker J. Comparison of naturally occurring and ligature-induced peri-implantitis bone defects in humans and dogs. Clin Oral Implants Res [Internet]. 2007 [cited 2019 Mar 18];18(2):161–170. Available from: http://doi.wiley.com/10.1111/j.1600-0501.2006.01320.x. Serino G, Turri A, Lang NP. Probing at implants with peri-implantitis and its relati...

References : Histological characteristics of advan...

Schwarz F, Derks J, Monje A, Wang H-L. Peri-implantitis. J Clin Periodontol. 2018;45(June 2016):S246–66. Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, et al. Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 World Workshop on the classification of periodontal and peri-implant diseases and conditions. J Clin Periodontol [Internet]. 2018 ...

Abbreviations : Histological characteristics of ad...

Most apical extension of the residual bone tissue Bone area Bone defect Bone-to-implant contact Bleeding on probing Cone beam computed tomography Confidence interval Disto-buccal Defect length Disto-oral Empty lacuna density Implant shoulder Mesio-buccal Marginal bone loss Mesio-oral Oral Osteocyte density Probing depth Residual bone Region of interest Surface area Standard de...

Availability of data and materials : Histological ...

The data sets used and/or analyzed during the current study are available from the corresponding author or reasonable request.

Conclusions : Histological characteristics of adva...

In conclusion, the findings of this case series based on dental implants that had to be retrieved because of advanced peri-implantitis and the concomitant inflammatory osteolysis suggest that the residual peri-implant bone might accumulate the functional load and is consequently modeled and reinforced to become cortical bone.

Discussion : Histological characteristics of advan...

When further interpreting the present study, the peri-implant osteocyte lacunae density after 1 to 27 years in function was reported [28]. In line with our findings, empty osteocytic lacunae adjacent to zirconia implants diagnosed with peri-implantitis were described [29]. Based on counting the osteocyte lacunae, we observed that numerous filled but also empty osteocytic lacunae were present withi...

Discussion : Histological characteristics of advan...

The present study was inspired by the concept that upon advanced loss of cortical peri-implant bone, the remaining peri-implant trabecular bone is subjected to masticatory forces and reinforced as a consequence of functional adaptation [15]. This adaptation depends on vital osteocytes [16]. Therefore, the present human case series aimed at investigate the peri-implant bone in advanced peri-implant...

Results : Histological characteristics of advanced...

The clinical and radiographic characteristics of the implant sites are presented in Table 1. In total, 3 implants were located in the maxilla, while two implants were located in the mandible. While all implants showed bleeding on probing, only 2 implants presented with suppuration on gentle probing. Mean probing depth was 6.3 ± 0.4 mm corresponding to a mean marginal bone loss (MBL) of 4.7 ± 1.0...

Materials and methods : Histological characteristi...

RB was divided into 500-μm-wide horizontal zones (from BD to A) following the long axis of the implant. For each of these individual zones, BIC and bone density (B.Ar/T.Ar) were determined. Osteocyte and empty osteocytic lacunae were counted along the region of interest (ROI) (i.e., the area encompassing the intra-thread regions along the buccal RB extension) (Fig. 1) using a software program (Im...

Materials and methods : Histological characteristi...

Cone beam computed tomographic (CBCT) scans were obtained from each patient for the surgical planning of implant removal. Linear measurements of the defect length (DL) at affected implants were made by drawing a vertical line, following the long axis of the implant, from the implant shoulder (IS) to the bottom of the defect (BD) at buccal and oral aspects in the CBCT data sets (Implant viewer, ver...

Materials and methods : Histological characteristi...

The present study included 4 patients, 3 female and 1 male (mean age of 66 ± 5 years), who attended the Implant Dentistry Department at Federal University of Santa Catarina, complaining of pain, discomfort, suppuration, and/or bleeding at implant sites. All patients revealed a history of periodontal disease, were non-smokers (100%), and reported no additional systemic diseases. The patients exhi...

Background : Histological characteristics of advan...

Peri-implantitis was recently defined as a “pathological condition occurring in tissues around dental implants”, which is “characterized by inflammation in the peri-implant connective tissue and a progressive loss of supporting bone” [1,2,3,4]. Human biopsies confirmed the presence of plasma cells, macrophages, and neutrophils [5] and elevated expression of inflammatory cytokines [6, 7] a...

Abstract : Histological characteristics of advance...

Inflammatory osteolysis is the clinical hallmark of peri-implantitis. The morphology of the remaining peri-implant bone and the level of osseointegration, however, remain unknown. Our aim was to characterize advanced peri-implantitis bone defects in humans. Four patients (3 female and 1 male) were diagnosed with peri-implantitis. A total of 5 implants with machined surfaces and a mean loading tim...

Fig. 7. The box plot shows the distribution of age...

Fig. 7. The box plot shows the distribution of age between the sex groups Fig. 7. The box plot shows the distribution of age between the sex groups

Fig. 6. Pie chart shows the distribution of loaded...

Fig. 6. Pie chart shows the distribution of loaded implants prosthetic restorations Fig. 6. Pie chart shows the distribution of loaded implants prosthetic restorations

Fig. 5. Pie charts shows the distribution of the d...

Fig. 5. Pie charts shows the distribution of the demographic datas of the patients Fig. 5. Pie charts shows the distribution of the demographic datas of the patients

Fig. 4. The crown-implant ratio measurement showin...

Fig. 4. The crown-implant ratio measurement showing a the length of the crown (red line) and b the length of the implant (red line) Fig. 4. The crown-implant ratio measurement showing a the length of the crown (red line) and b the length of the implant (red line)

Fig. 3. Fractal analysis stages. a Selected region...

Fig. 3. Fractal analysis stages. a Selected region of interest (ROI). b Cropped and duplicated version of ROI. c Addition of Gaussian filter. d Subtraction. e Addition of 128 pixels. f Binarized version. g Eroded version. h Dilated version. i Inverted version j Skeletonization Fig. 3. Fractal analysis stages. a Selected region of interest (ROI). b Cropped and duplicated version of ROI. c Addi...

Fig. 2. Region of interests (ROIs) were selected a...

Fig. 2. Region of interests (ROIs) were selected arbitrarily in a preoperative radiographic image and b a follow-up radiographic image Fig. 2. Region of interests (ROIs) were selected arbitrarily in a preoperative radiographic image and b a follow-up radiographic image

Fig. 1. Fractal dimension values measured from th...

Fig. 1. Fractal dimension values measured from the same area of interest on each panoramic radiograph over five different time intervals are shown in the figure. FD0, fractal dimension 0 (preoperative); FD1, fractal dimension 1 (0–1 months of follow-up); FD2, fractal dimension 2 (1–3 months of follow-up); FD3, fractal dimension 3 (6–12 months of follow-up); FD4, fractal dimension 4 ...

Table 2 Mean fractal dimension (FD) values before ...

  n Mean Standard deviation Minimum Maximum FD0 130 1.243 0.152 0.750 1.560 FD1 130 1.113 0.224 0.405 1.510 FD2 130 1.116 0.196 0.410 1.510 FD3 67 1.092 0.216 0.430 1.500 FD4 67 1.081 0.247 0.430 1.500   Table 2 Mean fractal dimension (FD) values before and after implant insertion

Table 1 Distribution and description of FD1 and FD...

 Failure (n)Success (n)P valuePowerEffect sizeSexWomen3870.0240.680.21Men634FD190.82 ± 0.28 (mean)0.45 (min)–1.26 (max)1211.13 ± 0.25 (mean)0.41 (min)–1.51 (max)< 0.0010.991.45FD290.97 ± 0.24 (mean)0.61 (min)–1.36 (max)1211.13 ± 0.19 (mean)0.41 (min)–1.51 (max)0.0230.990.79Crown-implant Ratio26.51 ± 3.89 (mean)3.77 (min)–9.27 (max)654.61 ± 1.58 (mean)2.57 min)–10.67 (max)0.101...

About this article : Evaluation of the peri-implan...

Kış, H.C., Güleryüz Gürbulak, A. Evaluation of the peri-implant bone trabecular microstructure changes in short implants with fractal analysis. Int J Implant Dent 6, 13 (2020). https://doi.org/10.1186/s40729-020-00209-7 Download citation Received: 12 September 2019 Accepted: 12 March 2020 Published: 01 April 2020 DOI: https://doi.org/10.1186/s40729-020-00209-7

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

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Ethics declarations : Evaluation of the peri-impla...

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study. Hatice Cansu Kış and Ayşegül Güleryüz Gür...

Author information : Evaluation of the peri-implan...

Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Nuh Naci Yazgan University, Kayseri, Turkey Hatice Cansu Kış Department of Prosthetic Dentistry, Faculty of Dentistry, Erciyes University, Kayseri, Turkey Ayşegül Güleryüz Gürbulak You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar AGG collecte...

Funding : Evaluation of the peri-implant bone trab...

The work was supported by the Department of Oral & Maxillofacial Radiology, Nuh Naci Yazgan University in Kayseri, Turkey.

Acknowledgements : Evaluation of the peri-implant ...

We would like to thank Editage (www.editage.com) for English language editing.

References : Evaluation of the peri-implant bone t...

Download references

References : Evaluation of the peri-implant bone t...

Mu T-J, Lee D-W, Park K-H, Moon I-S. Changes in the fractal dimension of peri-implant trabecular bone after loading: a retrospective study. Journal of periodontal & implant science. 2013;43(5):209–14. Zeytinoğlu M, İlhan B, Dündar N, Boyacioğlu H. Fractal analysis for the assessment of trabecular peri-implant alveolar bone using panoramic radiographs. Clinical oral investigations. 2015;19(2...

References : Evaluation of the peri-implant bone t...

Mandelbrot BB. The fractal geometry of nature: WH freeman New York; 1983. Sánchez I, Uzcátegui G. Fractals in dentistry. Journal of dentistry. 2011;39(4):273–92. Boutroy S, Bouxsein ML, Munoz F, Delmas PD. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. The Journal of Clinical Endocrinology & Metabolism. 2005;90(12):6508...

Abbreviations : Evaluation of the peri-implant bon...

Dental panoramic radiographs Fractal dimension 0 (preoperative) Fractal dimension 1 (0–1 months of follow-up) Fractal dimension 2 (1–3 months of follow-up) Fractal dimension 3 (6–12 months of follow-up) Fractal dimension 4 (12 + months of follow-up) Cone beam computed tomography Region of interest

Availability of data and materials : Evaluation of...

Not Applicable

Conclusion : Evaluation of the peri-implant bone t...

Fractal analysis is a useful method to measure the trabecular microstructure of bone in nonstandardized dental radiographs. The present study has a low power to reject the null hypothesis because of the low number of cases of failed implants. Therefore, further studies with a large sample size are warranted. Assessing a series of studies can provide certain cut-off values; this can enable to routi...

Discussion : Evaluation of the peri-implant bone t...

Fractal analysis of bone microstructure on dental radiographs may be useful for diagnostic applications; however, the histological microstructures of the bone cannot be visualized by any clinical imaging modality. Corpas et al. [12] stated that minor changes in bone occurring over a short-term period can be followed up with digital intraoral radiography; however, the results of radiographic fracta...

Discussion : Evaluation of the peri-implant bone t...

This study aimed to evaluate the microstructural changes in the peri-implant bone in patients with short implants in terms of the implant survival status by using fractal analysis measurements. In this study, a significant difference was found in the FD1 and FD2 values between the implant survival groups, and the mean FD1 and FD2 values of the success group were significantly higher than those of...

Results : Evaluation of the peri-implant bone trab...

Descriptive statistics were performed. The data were not normally distributed (p < 0.05). The intra-observer correlation coefficients of repeated measurements were 0.927, 0.889, 0.913, 0.988, 0.961, and 0.936 for FD0 (fractal dimension), FD1, FD2, FD3, FD4, and crown-implant ratio, respectively. Descriptive data are shown in Figs. 5, 6, and 7. A significant difference was found for sex between the...

Materials and methods : Evaluation of the peri-imp...

The crown-implant ratio was measured using the ImageJ version 1.38 software measuring tool in conjunction with a magnification tool. Each implant was measured from its bottom to the crown base and then from the crown base to its highest point (Fig. 4). All measurements were performed by a dento-maxillofacial radiologist who was blinded to patient information. To evaluate the intra-observer correl...

Materials and methods : Evaluation of the peri-imp...

This retrospective study was conducted in the dental clinic of Oral and Maxillofacial Radiology department and was approved by the local ethics committee (2013/203). The participants had approached the Prosthodontics Clinic between 2012 and 2019 for partial or complete tooth complaints. Among the data of 116 patients reviewed, panoramic radiographs of 67 patients were examined and included in this...

Backgrounds : Evaluation of the peri-implant bone ...

The quality of bone tissue at the site of implantation can be determined preoperatively with high accuracy, and changes in the trabecular structure, which is vital for the primary and secondary stability of the implant, can be observed during the follow-up after implantation. Previous studies have evaluated fractal analysis of peri-implant bone before and after loading. However, no study has exam...

Backgrounds : Evaluation of the peri-implant bone ...

Mandelbrot introduced fractals to describe his observation of shapes in nature, such as curves, surfaces, disconnected “dust,” and odd shapes. The word fractal originates from the Latin word “fractus,” which means broken. By using fractal mathematics, several studies have analyzed various fractal patterns in the human body. Fractal analysis is a mathematical method of describing complex sh...

Abstract : Evaluation of the peri-implant bone tra...

This study aimed to evaluate the microstructural changes in the peri-implant bone in patients with short implants in terms of implant survival status by using fractal analysis measurements. Dental panoramic radiographs (DPRs) of 67 patients were examined and included in this study. Fractal analysis and measurement of the crown-implant ratio were performed with ImageJ. The fractal analysis measure...

Fig. 5. PROMs over 5 years: improvement of satis...

Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end Fig. 5. PROMs over 5 years: improvement of satisfaction from loading to study end

Fig. 4. Soft tissue parameters at 5-year post-load...

Fig. 4. Soft tissue parameters at 5-year post-loading. a Plaque index: score 0, no plaque detected; score 1, plaque only recognized by running a probe across the smooth marginal surface of the implant; score 2, plaque seen by the naked eye; score 3, abundance of soft matter. b Sulcus bleeding index: score 0, no bleeding when a periodontal probe was passed along the gingival margin adjacent to th...

Fig. 3. Standardized peri-apical radiographs repre...

Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5-year post-loading (c) Fig. 3. Standardized peri-apical radiographs representing the bone level changes at the implant level: immediately post insertion (a), at loading (abutment/crown placement) (b), and at 5...

Fig. 2. Kaplan-Meier cumulative survival rate : Cl...

Fig. 2. Kaplan-Meier cumulative survival rate Fig. 2. Kaplan-Meier cumulative survival rate

Fig. 1. Study flow-chart: assessments and reason f...

Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits Fig. 1. Study flow-chart: assessments and reason for dropouts. Study visits were done according to standard procedures in the respective study centers. Blue, mandatory visits; gray, optional visits

Table 3 Mean crestal bone level changes in mm : Cl...

Bone level changenMeanSDInsertion-loading103− 0.520.55Loading-1-year follow-up93− 0.040.37Loading-3-year follow-up90− 0.040.40Loading-5-year follow-up86− 0.090.43Table 3 Mean crestal bone level changes in mm

Table 2 Demography of study population : Clinical ...

CharacteristicsCategoryTotalTotal patients/implantsn94/130Center 19/17Center 218/26Center 320/26Center 414/16Center 518/26Center 615/19Gender, n (%)Male30 (31.9)Female64 (68.1)Age at surgery, yearsMean ± SD50.4 ± 13.7Range (min/max)19.1-75.6Age range distribution, n (%)< 30 years8 (8.5)30-45 years22 (23.4)45-60 years38 (40.4)60-75 years25 (26.6)> 75 years1 (1.1)Tobacco use, n (%)Non-sm...

Table 1 Dropouts over observation time : Clinical ...

Time periodPatientsImplantsBefore loading58Loading-1 year681-3 years673-5 years13Total1826Table 1 Dropouts over observation time

About this article : Clinical and patient-reported...

Ackermann, KL., Barth, T., Cacaci, C. et al. Clinical and patient-reported outcome of implant restorations with internal conical connection in daily dental practices: prospective observational multicenter trial with up to 7-year follow-up. Int J Implant Dent 6, 14 (2020). https://doi.org/10.1186/s40729-020-00211-z Download citation Received: 16 December 2019 Accepted: 12 Ma...

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Clinical and patient-repo...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Clinical and patient-reporte...

A written consent was given by all patients after being informed of the study. The study was performed following the declaration of Helsinki. Ethics committee approval was obtained from the international ethical committee of Freiburg (Germany, Ref. 010/1833). Not applicable. All authors declare that they have no conflicts of interest regarding this study. All authors have been lecturing for Caml...

Author information : Clinical and patient-reported...

Filderstadt, Germany Karl-Ludwig Ackermann Leipzig, Germany Thomas Barth Munich, Germany Claudio Cacaci Landsberg a. L., Germany Steffen Kistler Forchheim, Germany Markus Schlee Department of Maxillofacial Surgery, Goethe University Frankfurt, Frankfurt, Germany Markus Schlee Berlin, Germany Michael Stiller You can also search for this author in PubMed Googl...

Funding : Clinical and patient-reported outcome of...

This study was funded by an unrestricted grant (NISCAM01/10) of the Oral Reconstruction Foundation (previously CAMLOG Foundation).

Acknowledgements : Clinical and patient-reported o...

The authors thank Lucius Keller of Touchpoint Communication AG (Luzern, Switzerland) for the medical writing support.

References : Clinical and patient-reported outcome...

Chang M, Odman PA, Wennstrom JL, Andersson B. Esthetic outcome of implant-supported single-tooth replacements assessed by the patient and by prosthodontists. Int J Prosthodont. 1999;12(4):335–41. Kiltz U, Winter J, Schirmer M, Weber U, Hammel L, Baraliakos X, et al. German translation and cross-cultural adaptation of the ASAS health index: an ICF-based instrument for documentation of functional...

References : Clinical and patient-reported outcome...

Ravald N, Dahlgren S, Teiwik A, Grondahl K. Long-term evaluation of Astra Tech and Branemark implants in patients treated with full-arch bridges. Results after 12-15 years. Clin Oral Implants Res. 2013;24(10):1144–51. Schwarz F, Alcoforado G, Nelson K, Schaer A, Taylor T, Beuer F, et al. Impact of implant-abutment connection, positioning of the machined collar/microgap, and platform switching...

References : Clinical and patient-reported outcome...

Gupta S, Sabharwal R, Nazeer J, Taneja L, Choudhury BK, Sahu S. Platform switching technique and crestal bone loss around the dental implants: a systematic review. Ann Afr Med. 2019;18(1):1–6. Hsu YT, Lin GH, Wang HL. Effects of platform-switching on peri-implant soft and hard tissue outcomes: a systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2017;32(1):e9–e24. Nelson K,...

References : Clinical and patient-reported outcome...

Cacaci C, Ackermann KL, Barth T, Kistler S, Stiller M, Schlee M. A non-interventional multicenter study to document the implants success and survival rates in daily dental practices of the CONELOG screw-line implant. Clin Oral Investig. 2019;23(6):2609–16. Cochran D, Oates T, Morton D, Jones A, Buser D, Peters F. Clinical field trial examining an implant with a sand-blasted, acid-etched surface...

References : Clinical and patient-reported outcome...

Krennmair G, Seemann R, Weinlander M, Piehslinger E. Comparison of ball and telescopic crown attachments in implant-retained mandibular overdentures: a 5-year prospective study. Int J Oral Maxillofac Implants. 2011;26(3):598–606. Slot W, Raghoebar GM, Cune MS, Vissink A, Meijer HJA. Four or six implants in the maxillary posterior region to support an overdenture: 5-year results from a randomize...

Abbreviations : Clinical and patient-reported outc...

Adverse event Bone level change Distance implant shoulder to first visible bone contact Orthopantomogram Plaque index Patient reported outcome measures Platform switching Sulcus bleeding index

Availability of data and materials : Clinical and ...

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Conclusions : Clinical and patient-reported outcom...

This prospective observational multicenter study demonstrated successful functional and esthetic outcomes of the study implant restorations (single tooth restoration, fixed partial dentures) with reliable peri-implant hard and soft tissue stability and high patients’ satisfaction. The results are comparable with the outcome of already published controlled randomized clinical studies and retrospe...

Discussion : Clinical and patient-reported outcome...

In recent years, patients’ needs have increased in terms of the esthetic and functional outcome of the dental restoration. PROMs have been reported in several studies and represent a well-described non-invasive method to measure patient’s satisfaction with these needs; however, they might present a lack of standardization [39, 40] due to the very subjective view on esthetics or functionality o...

Discussion : Clinical and patient-reported outcome...

Changes in crestal bone level are well-documented in the literature. Bone remodeling is reported to take place between surgery and loading. The reported changes are generally around 0.5 mm [17, 27, 30] but can reach more than 1 mm [31] in randomized or observational trials. The present study is well in accordance with these findings with its bone remodeling of − 0.52 ± 0.55 mm. Nearly 45%...

Discussion : Clinical and patient-reported outcome...

Endosseous dental implants are a commonly accepted treatment procedure and showed high survival and success rates as well as good functional performance in numerous clinical trials and retrospective analyses, also for Conelog implants as for their specific implant surface [17, 23, 26]. However, in general, one could argue that results of controlled clinical studies do not reflect the real situatio...

Results : Clinical and patient-reported outcome of...

Table 3 shows the mean bone level changes of the implants with available radiographs from insertion to 5-year post-loading. Bone remodeling around the implant was noticeable from surgery to loading, presenting a mean value of − 0.52 ± 0.55 mm. From loading to the 5-year follow-up, the mean change in crestal bone remained clinically stable (−0.09 ± 0.43 mm) (Fig. 3). Split into three g...

Results : Clinical and patient-reported outcome of...

The study was started with 94 patients with 130 implants. At the end of the study (5-year post-loading), 76 patients with 104 implants were considered for analysis. Dropouts were distributed over the time of the study as described in Table 1. The majority of dropouts occurred early in the study phase. The reasons for the dropouts were variable as described in Fig. 1. The demographic and clinica...

Methods : Clinical and patient-reported outcome of...

The study data, soft and hard tissue parameters as well as the PROMs were descriptively analyzed using IBM SPSS V25.0 (IBM Corp., Armonk, NY, USA): Categorical variables were shown with frequencies and mean values were used for continuous variables. Survival analysis was performed using Kaplan–Meier method. Time of loading was the study baseline as per protocol, and the statistical unit was the ...

Methods : Clinical and patient-reported outcome of...

Patients were scheduled to follow-ups at 6 months, 1-, 2-, 3-, 4-, and 5-year post-loading for the assessment of the study parameter (Fig. 1). Depending on the investigators’ standard post-operative protocol, follow-up appointments were scheduled slightly differently: One center skipped the control visits at 6 months. Additionally, due to the observational character of the study and the pati...

Methods : Clinical and patient-reported outcome of...

This is an observational multicenter clinical study, approved by the ethics committee of the Freiburg ethics commission international (feci 010/1833). The study was planned and conducted according to the German medical devices law, the Declaration of Helsinki, good clinical practice, and the reporting is aligned with the STROBE statement. A minimum of 90 to 100 patients were planned to be included...

Introduction : Clinical and patient-reported outco...

Features of the chosen implant system for a study may also influence the outcome of the treatment: The degree of the manufacturer’s tolerances of implants with a conical implant-abutment connection heightens the risk of a mispositioning of the abutment, which cannot be corrected by repeated torqueing. Platform switching (PS) implants tend to have a protective effect on hard implant tissue outcom...

Introduction : Clinical and patient-reported outco...

Many randomized controlled clinical trials have been published about dental implants. They have demonstrated long-term success in the rehabilitation of edentulous patients [1, 2] as well as patients with single or multiple teeth replacements [3, 4]. While this type of trials have an indispensable place in establishing a new product or a new operation technique regarding safety and efficacy, the r...

Abstract : Clinical and patient-reported outcome o...

The interpretation of the results of randomized clinical trials is often questioned in relation with daily circumstances in practices. This prospective observational multicenter study was instigated to reflect the need for information in real-life situations with dental implants with internal conical implant-abutment connection (Conelog implant system). The implants were followed up at least 5-yea...

Fig. 5. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 5. Anti-RANKL and anti-RANKL+miR-146a treatments decreased gingival mRNA expression of TNF-α and RANKL with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. Gingival tissues around ligatured implants and non-ligation implants were excised and processed for RT-qPCR analysis to determine mRNA level of TNF-α of WT mice (a) and TLR2/4 KO mice (b) (mean ± SD, n = ...

Fig. 4. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 4. Anti-RANKL and anti-RANKL+miR-146a treatments decreased the inflammatory cell infiltration of the implant gingival tissues with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. HE staining of the gingival tissue around implants were performed in the control group, ligation group, ligation with anti-RANKL antibody treatment group, and ligation with anti-RANKL ...

Fig. 3. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 3. Anti-RANKL and anti-RANKL+miR-146a treatments decreased TRAP-positive cell quantities with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. TRAP-positive cells (red color) with 3 or more nuclei were considered osteoclasts and were shown in the control group, ligation group, ligation with anti-RANKL antibody treatment group, and ligation with anti-RANKL antibo...

Fig. 2. Anti-RANKL and anti-RANKL+miR-146a treatme...

Fig. 2. Anti-RANKL and anti-RANKL+miR-146a treatments decreased ligature-induced bone resorption with different patterns in experimental peri-implantitis of WT and TLR2/4 KO mice. Buccal side images of the defleshed skulls were taken of the control (non-ligation) group, ligation (non-treatment) group, ligation with anti-RANKL antibody (ligation+AR) treatment group, and ligation with anti-RANKL a...

Fig. 1. Mouse model of ligature-induced experiment...

Fig. 1. Mouse model of ligature-induced experimental peri-implantitis. (a) Tooth extraction: left maxillary first and second molars extracted at 4 weeks old and the tooth extraction socket healed well with smooth gingiva surface after 6 weeks post-extraction. Implant placement: implant was put in alveolar bone without flap elevation. Ligature placement: at 4 weeks post-implant, 7-0 ligatur...

Table 1 Success rate (SR) of osseointegrated impla...

 Total implantsLostLooseOsseointegratedSuccess rate (%)SR P valueWild type group60654981.670.595TLR2/4 KO group60445286.67Table 1 Success rate (SR) of osseointegrated implants 4 weeks after implant placement

About this article : RANKL blockade alleviates per...

Pan, K., Hu, Y., Wang, Y. et al. RANKL blockade alleviates peri-implant bone loss and is enhanced by anti-inflammatory microRNA-146a through TLR2/4 signaling. Int J Implant Dent 6, 15 (2020). https://doi.org/10.1186/s40729-020-00210-0 Download citation Received: 24 September 2019 Accepted: 12 March 2020 Published: 15 April 2020 DOI: https://doi.org/10.1186/s40729-020-00210-0

Rights and permissions : RANKL blockade alleviates...

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Supplementary information : RANKL blockade allevia...

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Additional information : RANKL blockade alleviates...

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Ethics declarations : RANKL blockade alleviates pe...

Not applicable Not applicable Keqing Pan, Yang Hu, Yufeng Wang, Hao Li, Michele Patel, Danyang Wang, Zuomin Wang, and Xiaozhe Han certify that they do not have any commercial or associate interest that represents a conflict of interest in connection with the manuscript. The submitted work was not carried out in the presence of any personal, professional, or financial relationships that could pot...

Author information : RANKL blockade alleviates per...

You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar KP contributed to the conception and design; contributed to the acquisition, analysis, and interpretation of data; and drafted the manuscript. YH contributed to the conception and design, contributed to the acquisition, analysis, and interpretation of data; drafted the manu...

Author information : RANKL blockade alleviates per...

Department of Stomatology, The Affiliated Hospital of Qingdao University, College of Stomatology, Qingdao University, Qingdao, 266003, Shandong, China Keqing Pan Department of Immunology and Infectious Diseases, The Forsyth Institute, 245 First Street, Cambridge, MA, 02142, USA Keqing Pan, Yang Hu, Yufeng Wang, Hao Li, Michele Patel & Xiaozhe Han Department of Oral Medicine, Ninth People...

Funding : RANKL blockade alleviates peri-implant b...

This study was supported by NIH NIDCR R01DE025255 and the Forsyth Institute FPILOT36 to X Han and the Forsyth Institute FPILOT52 to Y Hu.

Acknowledgements : RANKL blockade alleviates peri-...

Not applicable

References : RANKL blockade alleviates peri-implan...

Tu S, Zhong D, Xie W, Huang W, Jiang Y, Li Y. Role of toll-like receptor signaling in the pathogenesis of graft-versus-host diseases. Int J Mol Sci. 2016;17(8). Gaddis DE, Michalek SM, Katz J. TLR4 signaling via MyD88 and TRIF differentially shape the CD4+ T cell response to Porphyromonas gingivalis hemagglutinin B. J Immunol. 2011;186(10):5772–83. Zhang P, Liu J, Xu Q, et al. TLR2-dependent m...

References : RANKL blockade alleviates peri-implan...

Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity. 2011;34(5):637–50. Song GG, Kim JH, Lee YH. Toll-like receptor (TLR) and matrix metalloproteinase (MMP) polymorphisms and periodontitis susceptibility: a meta-analysis. Mol Biol Rep. 2013;40(8):5129–41. Lin J, Bi L, Yu X, et al. Porphyromonas gingivalis exacerbates ligat...

References : RANKL blockade alleviates peri-implan...

Shuto T, Wachi T, Shinohara Y, Nikawa H, Makihira S. Increase in receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio in peri-implant gingiva exposed to Porphyromonas gingivalis lipopolysaccharide. J Dent Sci. 2016;11(1):8–16. O'Connell MB. Prescription drug therapies for prevention and treatment of postmenopausal osteoporosis. J Manag Care Pharm. 2006;12(6 Suppl A):S10-19; ...

References : RANKL blockade alleviates peri-implan...

Bertin TJC, Thivichon-Prince B, LeBlanc ARH, Caldwell MW, Viriot L. Current perspectives on tooth implantation, attachment, and replacement in amniota. Front Physiol. 2018;9:1630. Schminke B, Vom Orde F, Gruber R, Schliephake H, Burgers R, Miosge N. The pathology of bone tissue during peri-implantitis. J Dent Res. 2015;94(2):354–61. Mombelli A, Muller N, Cionca N. The epidemiology of peri-impl...

Abbreviations : RANKL blockade alleviates peri-imp...

Receptor activator of nuclear factor-kappa Β ligand Toll-like receptor Wild type MicroRNA 146a Micro-computed tomography Real-time quantitative PCR Tumor necrosis factor alpha Osteoprotegerin Lipopolysaccharides Hematoxylin and eosin Tartrate-resistant acid phosphatase

Availability of data and materials : RANKL blockad...

Presented in the main paper

Conclusions : RANKL blockade alleviates peri-impla...

In summary, the present study suggests that anti-inflammatory miR-146a enhance anti-RANKL-induced inhibition of peri-implant bone resorption through the regulation of TLR2/4 signaling and inhibition of TNF-α expression. Combination of regimens antagonizing both osteoclastogenesis and inflammation may become a more effective strategy to ameliorate peri-implantitis bone loss.

Discussion : RANKL blockade alleviates peri-implan...

According to the previous studies, miR-146a was regulated by NF-κB and blockade of miR-146a could decrease TLR4 and NF-κB in human cells [41, 42], suggesting that miR-146a is involved in TLR/NF-κB signaling pathway. Our recent study showed that miR-146a inhibited inflammatory cytokine secretion in B cells after challenged with P. gingivalis LPS and decreased bone resorption in experimental peri...

Discussion : RANKL blockade alleviates peri-implan...

Our present study showed that anti-RANKL antibody can significantly inhibit the bone loss in peri-implantitis and additional miR-146a treatment will enhance this inhibition through its anti-inflammation effects via TLR2/4 signaling. This is the first report in a murine model of peri-implantitis to demonstrate that anti-RANKL antibody and miR-146a together can significantly reduce bone resorption a...

Results : RANKL blockade alleviates peri-implant b...

In both WT mice and TLR2/4 KO mice, a significantly higher number of inflammatory cells were found infiltrating around the peri-implant tissues in the ligation group compared with the non-ligation group (Fig. 4a–c). However, the number of inflammatory cells in tissues of the ligation group was not significantly changed when treated with anti-RANKL antibody alone in both WT and TLR2/4 KO mice com...

Results : RANKL blockade alleviates peri-implant b...

In our ligature-induced experimental peri-implantitis mouse model, teeth extraction, implant placement, ligation placement, and gingival injection will be performed in a 12-week process (Fig. 1). 86.67% (52 out of 60) of implants in TLR2/4 KO mice achieved osteointegration (no mobility when touched by needles, no obvious bleeding upon probing) after being placed for 4 weeks, which has no signifi...

Methods : RANKL blockade alleviates peri-implant b...

Palatal gingival tissues were isolated from around ligatured implants and were homogenized in lysis buffer using a tissue homogenizer. Total RNA was extracted using PureLink® RNA Mini Kit (Ambion). cDNA was synthesized using the SuperScript III Reversed Transcriptase kit (Invitrogen) according to the manufacturer’s protocol. The mRNA expression of TNF-α and RANKL in gingival was determined by ...

Methods : RANKL blockade alleviates peri-implant b...

The ligations were maintained for 2 weeks, and after which the mice were euthanized by CO2 inhalation and the maxilla were harvested. The gingival tissues of half group of mice were isolated and collected for mRNA expression study. The skulls left were defleshed by beetles for 1 week. Briefly, in beetle’s chamber, freshly dissected skull was put in a paper cup with 0.5 cm diameter holes at...

Methods : RANKL blockade alleviates peri-implant b...

Wild-type (WT) C57BL/6 and TLR2 KO and TLR4 KO mice in C57/BL6 background were purchased from the Jackson Laboratory (Bar Harbor, ME). TLR2 and TLR4 double KO mice (TLR2/4 KO) were crossbreed from TLR2 KO and TLR4 KO mice and confirmed by genotyping. All the animal-associated protocols were reviewed and approved (#17-022) by the Institutional Animal Care and Use Committee of the Forsyth Institute....

Background : RANKL blockade alleviates peri-implan...

Toll-like receptors (TLR) are a family of well-characterized pattern recognition receptors (PRRs) and play an important role in the induction of pro-inflammatory cytokines by recognizing the signature molecules of the host innate immunity [25,26,27]. Our previous studies showed that TLR2 are associated with implant bone loss in a mouse model of peri-implantitis [5] and TLR4 is essential for period...

Background : RANKL blockade alleviates peri-implan...

Dental implant has become a preferable choice to restore the missing tooth in the past few decades for functional and esthetic purposes [1]. However, peri-implantitis has become prevalent accompanying the exponential growth of dental implant procedures [2, 3]. Peri-implantitis is indicated by infection of implant surrounding soft tissues and bone loss, resulting in implant failure eventually [4,5,...

Abstract : RANKL blockade alleviates peri-implant ...

This study suggests that anti-inflammatory miR-146a enhance anti-RANKL-induced inhibition of peri-implant bone resorption through the regulation of TLR2/4 signaling and inhibition of TNF-α expression.

Abstract : RANKL blockade alleviates peri-implant ...

The present study was to determine the effect of local anti-RANKL antibody administration in the presence or absence of microRNA-146a on ligature-induced peri-implant bone resorption, and the potential role of TLR2/4 signaling in such effect. Titanium implants were placed in the left maxilla alveolar bone 6 weeks after extraction of first and second molars in C57/BL6 wild-type (WT) and TLR2−/...

Fig. 6. Comparison of cleansability of each decont...

Fig. 6. Comparison of cleansability of each decontamination method on the different implant surfaces. Asterisk indicates p < 0.05 Fig. 6. Comparison of cleansability of each decontamination method on the different implant surfaces. Asterisk indicates p < 0.05

Fig. 5. Quantitative analysis of CFU counts on rou...

Fig. 5. Quantitative analysis of CFU counts on rough and machined surface implants after cleansing by each method. Asterisk represents vs Cont; a, vs G; b, vs US; c, vs Air; d, vs Rot; e, vs Las which indicates p < 0.05 Fig. 5. Quantitative analysis of CFU counts on rough and machined surface implants after cleansing by each method. Asterisk represents vs Cont; a, vs G; b, vs US; c, vs Air; d...

Fig. 4. SEM analysis of 4 areas. 1 Rough surface...

Fig. 4. SEM analysis of 4 areas. 1 Rough surface—microthread area. 2 Rough surface—macrothread area. 3 Machined surface—microthread area. 4 Machined surface—macrothread area Fig. 4. SEM analysis of 4 areas. 1 Rough surface—microthread area. 2 Rough surface—macrothread area. 3 Machined surface—microthread area. 4 Machined surface—macrothread area

Fig. 3. Decontamination methods. a Gauze soaked in...

Fig. 3. Decontamination methods. a Gauze soaked in saline applied using a sawing motion. b Ultrasonic scaler (SUPRASSON P-MAX, Satelec-Acteon group, Bordeaux, France, power setting: P5, tip: Implant Protect IP3L/R). c Air abrasives (AIR-FLOW MASTER PIEZON®, EMS, Nyon, Switzerland, power setting: water flow 100%, air pressure 75%, powder: AIR-FLOW® PERIO POWDER, nozzle: PERIO-FLOW® nozzles, di...

Fig. 2. GC Aadva® implant; 3.3-mm diameter, 8-mm ...

Fig. 2. GC Aadva® implant; 3.3-mm diameter, 8-mm length Fig. 2. GC Aadva® implant; 3.3-mm diameter, 8-mm length

Fig. 1. Hard resin splint model carrying 6 implant...

Fig. 1. Hard resin splint model carrying 6 implants Fig. 1. Hard resin splint model carrying 6 implants

Table 3 Quantitative analysis of CFU counts (× 10...

Rough surfaceContGUSAirRotLasMedian137.53.446.513.04.816.3Min73.00.36.80.50.63.0Max785.027.0240.035.537.034.0Machine surfaceContGUSAirRotLasMedian84.50.98.53.23.325.3Min43.00.20.92.01.60.4Max295.04.236.014.05.661.5Table 3 Quantitative analysis of CFU counts (× 105) from rough and machined surface implants after cleansing by each method

Table 2 Qualitative evaluation by SEM analysis of ...

Machined surface (microthread)No effectFairGoodExcellentG   +US  + Air  + Rot   +Las +  Machined surface (macrothread)No effectFairGoodExcellentG   +US  + Air  + Rot   +Las  + Table 2 Qualitative evaluation by SEM analysis of micro- and macrothread areas of machined surface implants

Table 1 Qualitative evaluation by SEM analysis of ...

Rough surface (microthread)No effectFairGoodExcellentG  + US +  Air +  Rot  + Las+   Rough surface (macrothread)No effectFairGoodExcellentG  + US  + Air  + Rot  + Las+   Table 1 Qualitative evaluation by SEM analysis of micro- and macrothread areas of rough surface implants

About this article : Evaluation of decontamination...

Otsuki, M., Wada, M., Yamaguchi, M. et al. Evaluation of decontamination methods of oral biofilms formed on screw-shaped, rough and machined surface implants: an ex vivo study. Int J Implant Dent 6, 18 (2020). https://doi.org/10.1186/s40729-020-00212-y Download citation Received: 06 February 2020 Accepted: 17 March 2020 Published: 22 April 2020 DOI: https://doi.org/10.118...

Rights and permissions : Evaluation of decontamina...

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material...

Additional information : Evaluation of decontamina...

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Evaluation of decontaminatio...

All participants provided informed consent verbally. Study information was disseminated to participants both verbally and in written form. This study protocol was approved by the ethical committee of Osaka University (H26.E-36). All participants consented to the publication of their data through a written consent form obtained from the ethical committee of Osaka University. Motohiro Otsuki, Masa...

Author information : Evaluation of decontamination...

Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan Motohiro Otsuki, Masahiro Wada, Yoshinobu Maeda & Kazunori Ikebe Department of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Osaka, Japan Masaya Yamaguchi & Shigetada Kawabata You can also search...

Funding : Evaluation of decontamination methods of...

GC Corporation provided the implants to this research.

Acknowledgements : Evaluation of decontamination m...

The authors thank Tomoaki Mameno for his work on data analysis.

References : Evaluation of decontamination methods...

Romeo E, Ghisolfi M, Murgolo N, Chiapasco M, Lops D, Vogel G. Therapy of peri-implantitis with resective surgery. A 3-year clinical trial on rough screw-shaped oral implants. Part I: clinical outcome. Clin Oral Implants Res. 2007;16(1):9–18. Aoki A, Mizutani K, Schwarz F, Sculean A, Yukna RA, Takasaki AA, et al. Periodontal and peri-implant wound healing following laser therapy. Periodontol 200...

References : Evaluation of decontamination methods...

Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, et al. Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018;89(Suppl 1):S313–8. Sousa V, Mardas N, Spratt D, Boniface D, Dard M, Donos N. Experimental models for contamination of ti...

References : Evaluation of decontamination methods...

Schwarz F, Ferrari D, Popovski K, Hartig B, Becker J. Influence of different air-abrasive powders on cell viability at biologically contaminated titanium dental implants surfaces. J Biomed Mater Res B Appl Biomater. 2009;88(1):83–91. Widodo A, Spratt D, Sousa V, Petrie A, Donos N. An in vitro study on disinfection of titanium surfaces. Clin Oral Implants Res. 2016;27(10):1227–32. Sahrmann P,...

References : Evaluation of decontamination methods...

Derks J, Schaller D, Hakansson J, Wennstrom JL, Tomasi C, Berglundh T. Effectiveness of implant therapy analyzed in a Swedish population: prevalence of peri-implantitis. J Dent Res. 2016;95(1):43–9. Fransson C, Lekholm U, Jemt T, Berglundh T. Prevalence of subjects with progressive bone loss at implants. Clin Oral Implants Res. 2005;16(4):440–6. Wada M, Mameno T, Onodera Y, Matsuda H, Daimon...

Abbreviations : Evaluation of decontamination meth...

Control (no decontamination) Gauze soaked in saline Ultrasonic scaler (SUPRASSON P-MAX, Satelec-Acteon Group, Bordeaux, France; power setting: P5, tip: Implant Protect IP3L/R) Air abrasive (AIR-FLOW MASTER PIEZON®, EMS, Nyon, Switzerland; power setting: water flow 100%, air pressure 75%, powder: AIR-FLOW® PERIO POWDER, nozzle: PERIO-FLOW® nozzles, distance from the nozzle to the implant 2 ...

Availability of data and materials : Evaluation of...

The datasets used during the current study are available from the corresponding author on reasonable request.

Conclusions : Evaluation of decontamination method...

In the present ex vivo experimental study, none of the tested decontamination methods thoroughly eliminated biofilms formed on rough/machined surface implants intraorally. Gauze soaked in saline and the rotary stainless steel instrument showed better cleansability than the ultrasonic scaler in qualitative and quantitative analyses and may be advantageous for cleansing contaminated implant surfaces...

Discussion : Evaluation of decontamination methods...

Through SEM analysis and CFU counts, it was demonstrated that, except for the Er:YAG laser, decontamination of the machined surface implant was easier than that of the rough surface implant regardless of decontamination method. Gauze soaked in saline and the ultrasonic scaler demonstrated a statistically significant difference in CFU counts between the two surfaces. In this context, a machined sur...

Discussion : Evaluation of decontamination methods...

Sahrmann et al. [15] tested three instruments (ultrasonic scaler, Gracey curette, and air abrasive device with glycine powder) on rough surface implants stained with indelible ink used as artificial plaque. There was a statistically significant difference in terms of stain removal rate. The air abrasive device showed the best result among the tested instruments. The result of this study is in line...

Discussion : Evaluation of decontamination methods...

It has been previously stated that the alteration of the implant surface during cleansing may attenuate biocompatibility [29]. However, several clinical studies revealed the considerable treatment effect even though there was certain expected damage on the implant surface [7, 34]. Therefore, it is assumed that the most important consideration for treating peri-implantitis in the clinical setting s...

Discussion : Evaluation of decontamination methods...

Regarding the air abrasives, the cleansing effect in the SEM analysis was also as considerable as that achieved by the ultrasonic scaler in the present study, in contrast to the results of the aforementioned study. Louropoulou et al. [29] also stated in their systematic review that an air-powder abrasive system with sodium bicarbonate powder could cleanse contaminated rough/smooth implant surfaces...

Discussion : Evaluation of decontamination methods...

Based on the results of the SEM qualitative analysis, gauze soaked in saline and the rotary stainless steel instrument consistently showed good cleansability on rough and machined surface implants compared with the other methods. Conversely, the Er:YAG laser showed inferior cleansability to all other methods especially on rough surface implants. The ultrasonic scaler and air abrasive exhibited fai...

Discussion : Evaluation of decontamination methods...

This study was performed following an ex vivo design to overcome the drawbacks of previous studies. One particular difference in this study was the use of a commercially available screw-shaped implant. As the implant shape and design have rather complicated macro- and microstructures compared with titanium disks or different forms of titanium commonly used in experimental studies, previous results...

Results : Evaluation of decontamination methods of...

During the experiment, three participants experienced small ulcers caused by the implants carried on the splints; however, it did not affect their daily life. Additionally, there were no signs of gingival inflammation in any participant. G and Rot achieved relatively clean implant surfaces compared with Las in micro- and macrothread areas. US and Air demonstrated fair cleansability in microthread...

Materials and methods : Evaluation of decontaminat...

The SEM analysis was performed as previously described [16,17,18]. The decontaminated implant samples were fixed with 2% glutaraldehyde-RPMI 1640 immediately for 1 h at room temperature and washed with distilled water. Then, the samples were dehydrated with 100% t-butyl alcohol and freeze-dried. Finally, the samples were coated with platinum and examined using an emission-scanning electron micro...

Materials and methods : Evaluation of decontaminat...

Eleven participants, nine men and two women between 28 and 42 years of age (mean age 31.3 ± 4.6), were recruited as the study subjects. All participants provided informed consent verbally. Study information was disseminated to participants both verbally and in written form. The inclusion criteria were as follows: Generally healthy subjects Dentate subjects without ill-fitting restorations (...

Background : Evaluation of decontamination methods...

Dental implants are now used broadly for recovering loss of masticatory function and esthetics. Although it has been revealed that dental implants can often survive long term, biological and mechanical complications may arise. Recent cross-sectional and retrospective studies noted a higher prevalence of peri-implantitis at the implant and subject level than previously considered [1,2,3,4]. Additio...

Abstract : Evaluation of decontamination methods o...

To evaluate the effect of several representative decontamination methods of oral biofilms on different implant surfaces. Eleven participants wore a hard resin splint carrying 6 rough (GC Aadva® implant; 3.3-mm diameter, 8-mm length) or machined (not commercially available) surface implants for 4 days to accumulate dental plaque naturally on the titanium surfaces of the implants. Apart from sur...

Figure 9. Q14. Do you have any requests for dentis...

Figure 9. Q14. Do you have any requests for dentists who practice implant treatment? Figure 9. Q14. Do you have any requests for dentists who practice implant treatment?

Figure 8. Q13. What are the frequently received re...

Figure 8. Q13. What are the frequently received repair requests for IODs? Figure 8. Q13. What are the frequently received repair requests for IODs?

Figure 7. Q12. What kind of creative steps do you ...

Figure 7. Q12. What kind of creative steps do you take in order to prevent veneer fracture and chipping in the molar region? Figure 7. Q12. What kind of creative steps do you take in order to prevent veneer fracture and chipping in the molar region?

Figure 6. Q11. What are the frequently received re...

Figure 6. Q11. What are the frequently received repair requests involving implant fixed prostheses? Figure 6. Q11. What are the frequently received repair requests involving implant fixed prostheses?

Figure 5. Q10. What are the main fabrication chall...

Figure 5. Q10. What are the main fabrication challenges faced? Figure 5. Q10. What are the main fabrication challenges faced?

Figure 4. Q8. What are the proportions of attachme...

Figure 4. Q8. What are the proportions of attachment types used with IODs? Figure 4. Q8. What are the proportions of attachment types used with IODs?

Figure 3. Q6. What types of implant fixed prosthes...

Figure 3. Q6. What types of implant fixed prostheses are used in the posterior region? Figure 3. Q6. What types of implant fixed prostheses are used in the posterior region?

Figure 2. Q5. What types of materials (i.e. veneer...

Figure 2. Q5. What types of materials (i.e. veneer, coping) are used to make implant prostheses in the anterior region? Figure 2. Q5. What types of materials (i.e. veneer, coping) are used to make implant prostheses in the anterior region?

Figure 1. Q4. What are the proportions of abutment...

Figure 1. Q4. What are the proportions of abutments used with cement-retained prostheses? Figure 1. Q4. What are the proportions of abutments used with cement-retained prostheses?

Table 4 Prosthetic complic...

Question   Values Q9. What are the main issues generally encountered? Compatibility precision issues 29.6% Aesthetic issues 33.2% ...

Table 3 Implant overdentur...

Question   Values Q7. The design of the implant overdenture: Decision made according to instructions of dentist 43.2% Work is left to technicians 19.3% ...

Table 2 Implant fixed pros...

Question   Values Q3. The percentages of implant fixed prostheses: Cement-retained 61.4% Screw-retained 38.6% ...

Table 1 Conditions charact...

Question   Values Q1. The years of experience working as a dental technician, and the number of dentists from whom job orders are received.   Mean (SD) 17.0 (6.8) years 36.5(12.4)/Lab. ...

About this article : Current status of implant pro...

Hagiwara, Y., Narita, T., Shioda, Y. et al. Current status of implant prosthetics in Japan: a survey among certified dental lab technicians. Int J Implant Dent 1, 4 (2015). https://doi.org/10.1186/s40729-015-0005-3 Download citation Received: 13 October 2014 Accepted: 22 January 2015 Published: 17 February 2015 DOI: https://doi.org/10.1186/s40729-015-0005-3

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and in...

Additional information : Current status of implant...

The authors have declare that they have no competing interests. TN, YS, KI, TI and SN were compiled and aggregate of the questionnaire. YH and TS conceived of the study and participated in its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript.

Author information : Current status of implant pro...

Implant Dentistry, Nihon University School of Dentistry, Dental Hospital, 1-8-13 Kandasurugadai, Chiyoda-ku, Tokyo, 101-8310, Japan Yoshiyuki Hagiwara, Tatsuya Narita, Yohei Shioda, Keisuke Iwasaki, Takayuki Ikeda & Shunsuke Namaki Department of Dental Specialties, Mayo Clinic, Mayo Clinic, 200 First Street SW, Rochester, MINN, 55905, USA Thomas J Salinas You can also search for this aut...

Acknowledgements : Current status of implant prost...

This paper was partially supported by a Grant-in-Aid for Scientific Research (C) (No. 24592935) from the Japan Society for the Promotion of Science.

References : Current status of implant prosthetics...

Larsson C. Vult von Steyern P. Five-year follow-up of implant-supported Y-TZP and ZTA fixed dental prostheses. A randomized, prospective clinical trial comparing two different material systems. Int J Prosthodont. 2010;23:555–61. Gonda T, Maeda Y. Why are magnetic attachments popular in japan and other asian countries? Jpn Dental Sci Rev. 2011;47:124–30. Carlsson GE, Kronström M, de Baat C, ...

References : Current status of implant prosthetics...

Andreiotelli M, Att W, Strub JR. Prosthodontic complications with implant overdentures: a systematic literature review. Int J Prosthodont. 2010;3:195–203. Cehreli MC, Karasoy D, Kokat AM, Akca K, Eckert SE. Systematic review of prosthetic maintenance requirements for implant-supported overdentures. Int J Oral Maxillofac Implants. 2010;25:163–80. Hatzikyriakos A, Petridis HP, Tsiggos N, Sakel...

References : Current status of implant prosthetics...

Gatten DL, Riedy CA, Hong SK, Johnson JD, Cohenca N. Quality of life of endodontically treated versus implant treated patients: a University-based qualitative research study. J Endocrinol. 2011;37:903–9. Johannsen A, Wikesjö U, Tellefsen G, Johannsen G. Patient attitudes and expectations of dental implant treatment—a questionnaire study. Swed Dent J. 2012;36:7–14. Pavel K, Seydlova M, Dos...

References : Current status of implant prosthetics...

Att W, Stappert C. Implant therapy to improve quality of life. Quintessence Int. 2003;34:573–81. Papaspyridakos P, Chen CJ, Singh M, Weber HP, Gallucci GO. Success criteria in implant dentistry: a systematic review. J Dent Res. 2012;91:242–8. Shumaker ND, Metcalf BT, Toscano NT, Holtzclaw DJ. Periodontal and periimplant maintenance: a critical factor in long-term treatment success. Compend C...

Conclusions : Current status of implant prosthetic...

This survey served to clarify the current status of implant prosthodontics, issues, and considerations in their fabrication, and the status of prosthetic complications and preventive initiatives, all from a laboratory perspective. Concerning implant treatment, it was concluded that dentists either play the leading role or work in collaboration with technicians, including in the formulation of tre...

Results and discussion : Current status of implant...

Finally, technicians gave voice to the several requests for dentists, who are their customers, as a result of their daily experiences accomplishing implant laboratory procedures (Q14) (Figure 9). These included asking dentists to use suitable implant location and orientation (31.8%), to allow technicians to participate and consult with technicians from the treatment planning stage (28.3%), to imp...

Results and discussion : Current status of implant...

The questionnaire revealed several creative steps, based on laboratory considerations, being taken to prevent veneer chipping and fractures, a frequent and problematic prosthetic complication (Q12) (Figure 7). Technicians were taking into account metal (including zirconia) coping designs (36.3%), covering only the distal-most part of the molar region with metal (24%), using veneering composite re...

Results and discussion : Current status of implant...

Looking at repair requests (i.e., complications) involving the superstructures of fixed implant prostheses (Q11) (Figure 6), facing damage and chipping accounted for more than half of all requests (54.5%). Generally speaking, there are many reports that indicate a high incidence of complications related to fixed prostheses involving abutment screw loosening, detachment of cement-retained crowns, ...

Results and discussion : Current status of implant...

Bar and clip attachments were most commonly used for IODs, followed by magnet, ball, and socket, and Locator attachments (Q8) (Figure 4). It is noteworthy among the questionnaire results that magnetic attachment use is highest in Asian countries, including Japan [43]. Additionally, it is thought that the low use of Locators (5.2%) is strongly influenced by Japan’s strict pharmaceutical regulati...

Results and discussion : Current status of implant...

Concerning the types of prostheses used in the posterior region (Q6) (Figure 3), PFM design accounts for about 40% of the total, although the questionnaire also revealed a trend (in 9.1% of all cases) toward metal occlusal designs to avoid fracture and chipping of the veneer material. The same trend is evident in indirect composite facing crowns, where metal occlusal designs are used in about 35%...

Results and discussion : Current status of implant...

Next, concerning the types of abutments used with cement-retained prostheses (Q4) (Figure 1), CAD/CAM abutments accounted for about one third of the total (titanium, 19.7%; zirconia, 12.1%), and custom UCLA-type abutments made from cast gold alloy accounted for about the same proportion. It is likely that this breakdown is because, in many cases, implant systems using fabricated crowns are not su...

Results and discussion : Current status of implant...

Dentists play a leading role in 39.3% of the time in implant treatment planning and prosthetic design, and dental technicians are consulted concerning cases and part usage 34.7% of the time, suggesting the approach to implants is driven by prosthetic considerations (by dentists) to some degree. However, because dental technicians indicated that they take the initiative 15% of the time, it is impos...

Results and discussion : Current status of implant...

Out of 120 surveys sent, 74 technicians responded, resulting in a response rate of 61.6%. A summary of the responses is provided in Tables 1, 2, 3, and 4 and Figures 1, 2, 3, 4, 5, 6, 7, 8, and 9. Because implant treatment (implant prostheses) requires a significant amount of specialized, high-precision laboratory procedures, this area of dental care exhibits slightly different trends than pros...

Methods : Current status of implant prosthetics in...

This cross-sectional questionnaire survey was performed among the certified dental technicians of JSOI from September to December in 2011. Selected were 120 out of 285 certified dental technicians of JSOI using a random number table and mailing each questionnaire directly to the participant. To facilitate coverage of a broad range of topics, the survey classified content into the following four ca...

Background : Current status of implant prosthetics...

This survey consists of a questionnaire targeting the certified dental technicians of the Japanese Society of Oral Implantology (JSOI) [32] who are primarily involved in fabricating dental implant restorations. It was formulated to clarify the current status of implant prostheses from a prosthetic and technician-oriented standpoint through questions addressing current trends among dental implant t...

Background : Current status of implant prosthetics...

Currently, dental implant treatment is evaluated on the basis not only of restoring masticatory function, but also a variety of other factors, including the implant and superstructure survival rate and psychological impacts [1-3]. Numerous factors must be taken into account, to offer highly predictable implant treatment, and there is no doubt that prosthetic-related factors such as the type and co...

Abstract : Current status of implant prosthetics i...

There are many implant cases in which dental technicians take initiative with regard to the design of implant prostheses, and to a certain extent, this area of care is one in which dentists do not necessarily play the leading role. Moreover, inadequate communication between dental technicians and dentists and insufficient instructions for technicians has been highlighted as issues in the past. The...

Figure 2. Summary of biological processes identifi...

Figure 2. poietic stem cells; MP, macrophages; OC, osteoclasts. Figure 2. Summary of biological processes identified via gene expression during early peri-implant bone healing. CKs, cytokines; GFs, growth factors; EPC, endothelial progenitor cells; EC, endothelial cells; MSC, mesenchymal stem cells; OB, osteoblasts; ECM, extracellular matrix; HSC, haematopoietic stem cells; MP, macrophages; O...

Figure 1. Flowchart for study selection (n  ...

Figure 1. Flowchart for study selection ( Figure 1. Flowchart for study selection ( n  = number of studies).

Table 4 Summary of biolo...

Process Upregulated genes Category (gene code) Inflammation/immune response   Pro-inflammatory cytokines Tumor necrosis factor (TNF-a, TNFSF9) Interleukin (IL-6, IL-2, IL-1 F9, IL-23A, ...

Table 3 Summary of findi...

Study Ivanovski et al. [ 34 ] Donos et al. [ 35 ] Bryington et al. [ 36 ] Thalji et al. [ 37 ] Design 9 patients; 9 implants placed 18 patients; 18 implants placed 10 patients;...

Table 2 Assessment of ri...

Category Ivanovski et al. [ 34 ] Donos et al. 2011 [ 35 ] Bryington et al. [ 36 ] Thalji et al. [ 37 ] Study design   Comparison None (only SLActive) SLA vs. SLActive TiOBlast vs. Osseospeed TiOBlast vs. Osseospeed   Setting University University University University   Population, inclusion criteria 9 healthy volunteers with no mandibular thi...

Table 1 Assessment of th...

Methodology Ivanovski et al. [ 34 ] Donos et al. [ 35 ] Bryington et al. [ 36 ] Thalji et al. [ 37 ] Tissue harvesting Tissue attached to implant carefully removed with a curette, preexisting hard tissue discarded Tissue attached to ...

About this article : Genomic analyses of early per...

Shanbhag, S., Shanbhag, V. & Stavropoulos, A. Genomic analyses of early peri-implant bone healing in humans: a systematic review. Int J Implant Dent 1, 5 (2015). https://doi.org/10.1186/s40729-015-0006-2 Download citation Received: 14 November 2014 Accepted: 27 January 2015 Published: 01 March 2015 DOI: https://doi.org/10.1186/s40729-015-0006-2

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The authors declare that they have no competing interests. SS conceived and carried out the study and drafted the manuscript. VS and AS participated in carrying out the study and drafting the manuscript. All authors read and approved the final manuscript.

Author information : Genomic analyses of early per...

Department of Periodontology, Faculty of Odontology, Malmö University, Carl Gustafs väg 34, 214 21, Malmö, Sweden Siddharth Shanbhag & Andreas Stavropoulos Centre for Oral Rehabilitation & Implant Dentistry, 1 Laxmi Niwas, 87 Bajaj Road, Vile Parle West, Mumbai, 400056, India Siddharth Shanbhag & Vivek Shanbhag You can also search for this author in PubMed Goog...

References : Genomic analyses of early peri-implan...

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References : Genomic analyses of early peri-implan...

Donos N, Retzepi M, Wall I, Hamlet S, Ivanovski S. In vivo gene expression profile of guided bone regeneration associated with a microrough titanium surface. Clin Oral Implants Res. 2011;22(4):390–8. doi:10.1111/j.1600-0501.2010.02105.x. Skaper SD. The neurotrophin family of neurotrophic factors: an overview. Methods Mol Biol. 2012;846:1–12. doi:10.1007/978-1-61779-536-7_1. Vaillant AR, Mazz...

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Nucera S, Biziato D, De Palma M. The interplay between macrophages and angiogenesis in development, tissue injury and regeneration. Int J Dev Biol. 2011;55(4–5):495–503. doi:10.1387/ijdb.103227sn. Ziebart T, Schnell A, Walter C, Kämmerer PW, Pabst A, Lehmann KM, et al. Interactions between endothelial progenitor cells (EPC) and titanium implant surfaces. Clin Oral Investig. 2013;17(1):301–...

References : Genomic analyses of early peri-implan...

Rocci M, Rocci A, Martignoni M, Albrektsson T, Barlattani A, Gargari M. Comparing the TiOblast and Osseospeed surfaces. Histomorphometric and histological analysis in humans. Oral Implantol (Rome). 2008;1(1):34–42. Qin C, Baba O, Butler WT. Post-translational modifications of sibling proteins and their roles in osteogenesis and dentinogenesis. Crit Rev Oral Biol Med. 2004;15(3):126–36. Vlaci...

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Chehroudi B, Ghrebi S, Murakami H, Waterfield JD, Owen G, Brunette DM. Bone formation on rough, but not polished, subcutaneously implanted Ti surfaces is preceded by macrophage accumulation. J Biomed Mater Res A. 2010;93(2):724–37. doi:10.1002/jbm.a.32587. Heng BC, Cao T, Stanton LW, Robson P, Olsen B. Strategies for directing the differentiation of stem cells into the osteogenic lineage in vit...

References : Genomic analyses of early peri-implan...

Nishimura I. Genetic networks in osseointegration. J Dent Res. 2013;92(12 Suppl):109S–18. doi:10.1177/0022034513504928. Higgins JPT, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from www.cochrane-handbook.org; 2011. Tarca AL, Romero R, Draghici S. Analysis of microarray experiments of...

References : Genomic analyses of early peri-implan...

Lin Z, Rios HF, Volk SL, Sugai JV, Jin Q, Giannobile WV. Gene expression dynamics during bone healing and osseointegration. J Periodontol. 2011;82(7):1007–17. doi:10.1902/jop.2010.100577. Ai-Aql ZS, Alagl AS, Graves DT, Gerstenfeld LC, Einhorn TA. Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis. J Dent Res. 2008;87(2):107–18. Albrektsson T...

References : Genomic analyses of early peri-implan...

Setzer FC, Kim S. Comparison of long-term survival of implants and endodontically treated teeth. J Dent Res. 2014;93(1):19–26. doi:10.1177/0022034513504782. Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52(2):155–70. Berglundh T, Abrahamsson ...

Conclusions : Genomic analyses of early peri-impla...

Based on limited evidence of gene expression data from four studies involving 43 patients, the following remarks can be made: Early peri-implant healing (2 weeks) involves a sequence of biological events which are similar to those observed in other bone wound healing scenarios (fractures, extraction-sockets). Osseointegration depends on osteogenesis at the implant interface, but other simultane...

Results and discussion : Genomic analyses of early...

It can be hypothesized that peri-implant neurogenesis is one of the underlying mechanisms governing the phenomenon of osseoperception, defined as the tactile sensibility of osseointegrated implants to occlusal forces induced via activation of nerve endings and/or receptors in the peri-implant environment [82,83]. Moreover, recent evidence suggests that implant surface properties may influence the ...

Results and discussion : Genomic analyses of early...

In the present review, a significant simultaneous upregulation of several angiogenesis-related genes was identified at day 7 in all included studies. Pro-angiogenic factors (ANXA2, EPAS-1) were upregulated at TiOBlast and Osseospeed surfaces at day 7 [37]. Genes associated with VEGF and P13K-AKT signaling pathways were upregulated at SLActive (but not SLA) surfaces on day 7 and continued to be upr...

Results and discussion : Genomic analyses of early...

Furthermore, genes associated with collagen fibril formation/organization (heat-shock protein-47 (HSP-47), pro-collagen C-endopeptidase enhancer (PCOLCE), small leucine-rich proteoglycans (SLRP)) and post-translational modification (pro-collagen lysyl-hydroxylases (PLOD1, PLOD2, PLOD3) and lysyl-oxidase (LOX)) were upregulated on Osseospeed and TiOBlast surfaces [37]. Collagen comprises approximat...

Results and discussion : Genomic analyses of early...

The key signaling pathways, via which GFs guide osteogenic cell differentiation, are the TGF-β/BMP- and Wnt-mediated pathways [19,47]. While the BMP pathway ensures differentiation of MSCs into osteo-chondro-progenitors (OCPs), the Wnt pathway is essential for subsequent osteoblastic commitment, i.e., Wnt acts ‘downstream’ of BMP to ensure that OCPs differentiate into osteoblasts and not chon...

Results and discussion : Genomic analyses of early...

Cells along the osteogenic differentiation pathway may be artificially categorized as (1) undifferentiated MSCs, (2) osteo-chondro-progenitor cells, (3) pre-osteoblasts, and (4) osteoblasts; although in reality, a developmental continuum without distinct boundaries may exist [43]. While pre-differentiated osteoblasts in the marrow compartment only play a minor role in bone wound healing, a more pr...

Results and discussion : Genomic analyses of early...

Thus, high risk of bias should be considered when interpreting the results, due to the above methodological limitations and the overall limited information (four studies) available. Conventional implant surgery involves osteotomy preparation and insertion of the implant into the alveolar bone. The immediate local effects of this procedure, functionally relevant to subsequent healing processes, ar...

Results and discussion : Genomic analyses of early...

The included studies basically report on commercially available implants from two major manufacturers and involve comparisons of different implant surface technologies in regard with topography and/or chemistry modifications within each implant system. Various analyses were performed in the included studies; however, an attempt has been made to synthesize the various findings and discuss them here...

Methods : Genomic analyses of early peri-implant b...

Both reviewers independently extracted data from the full texts of included articles using specially designed forms. Data on author(s), study design, implant type/surface, any additional procedures performed, number of patients (in each group), presence of a control group, procedure and time of implant retrieval, methods of gene expression analysis, and main results, were extracted. Descriptive su...

Methods : Genomic analyses of early peri-implant b...

A study protocol for a systematic qualitative literature review was developed based on recommended methods [29]. The focused question was ‘what biological processes are reflected by gene expression analyses in peri-implant tissues of humans during the early stages (up to 4 weeks) of healing?’ All studies, controlled (using different implants) or uncontrolled, reporting gene expression analys...

Review : Genomic analyses of early peri-implant bo...

Recent in vitro [24] and preclinical in vivo [25] studies have focused on the early molecular biological responses to various titanium implant surfaces. Understanding these early responses is essential for efforts aiming to accelerate and enhance the process of osseointegration [26]. Upregulation or downregulation of specific genes in peri-implant tissues identified by analyses of genetic material...

Review : Genomic analyses of early peri-implant bo...

Osseointegrated oral implants are an integral part of modern reconstructive dentistry and are associated with favorable long-term therapeutic outcomes [1]. Osseointegration was originally defined as the direct contact between vital bone and a load-bearing implant observed at the light microscopic, i.e., histological, level [2]. Morphogenesis of implant osseointegration has been assessed in several...

Abstract : Genomic analyses of early peri-implant ...

The objective of the study was to systematically review the literature for studies reporting gene expression analyses (GEA) of the biological processes involved in early human peri-implant bone healing. Electronic databases (MEDLINE, EMBASE) were searched in duplicate. Controlled and uncontrolled studies reporting GEA of human peri-implant tissues - including ≥5 patients and ≥2 time points - ...

Table 3 Changes in values ...

  SBP (mmHg) DBP (mmHg) PR (bpm) RPP (bpm × mmHg) Normotensive patients (N = 410)  On arrival at the office 133.0 ± 18.4 76.4 ± 12.5 79.2 ± 13...

Table 2 Incidence of high ...

  SBP (>160 mmHg) RPP (>12,000 bpm × mmHg) Normotensive group (N = 410)  On arrival at the office 41 (10.0%) 111 (27.1%)  Prior to sedation ...

Table 1 Demographic and cl...

  Normotensive group Hypertensive group p value Number (male: female) 410 (127: 283) 106 (37: 69) 0.170 Age (year mean ± SD) ...

About this article : Efficacy of intravenous sedat...

Kimura, M., Takasugi, Y., Hanano, S. et al. Efficacy of intravenous sedation and oral nifedipine in dental implant patients with preoperative hypertension - a retrospective study of 516 cases. Int J Implant Dent 1, 6 (2015). https://doi.org/10.1186/s40729-015-0004-4 Download citation Received: 08 October 2014 Accepted: 14 January 2015 Published: 18 March 2015 DOI: https://doi.org/10.1186/s407...

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Motoshi Kimura, Yoshihiro Takasugi, Shigeyoshi Hanano, Katsuyuki Terabe and Yuko Kimura declare that they have no competing interests. YT and MK designed the study; MK, SH, and KT performed the surgeries; YT performed the intravenous sedation. YT, MK, and YK collected and analyzed the data; MK wrote the manuscript. YT revised the manuscript. All authors read and approved the final manuscript.

Author information : Efficacy of intravenous sedat...

Hanano Dental Clinic, 4-2-3 Yamanoue, Hirakata, Osaka, 573-0047, Japan Motoshi Kimura & Shigeyoshi Hanano Department of Anesthesiology, Kinki University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka, 589-8511, Japan Yoshihiro Takasugi Terabe Dental Clinic, 4-249 Sakae-cho, Tsu, Mie, 514-0004, Japan Katsuyuki Terabe First Department of Internal Medicine, Osaka Medical College...

References : Efficacy of intravenous sedation and ...

Abraham-Inpijn L, Borgmeijer-Hoelen A, Gortzak RAT. Changes in blood pressure, heart rate, and electrocardiogram during dental treatment with use of local anesthesia. J Am Dent Assoc. 1988;116:531–6. Brand HS, Gortzak RA, Palmer-Bouva CC, Abraham RE, Abraham-Inpijn L. Cardiovascular and neuroendocrine responses during acute stress induced by different types of dental treatment. Int Dent J. 1995...

References : Efficacy of intravenous sedation and ...

Little JW. The impact on dentistry of recent advances in the management of hypertension. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;90:591–9. Aubertin MA. The hypertensive patient in dental practice: updated recommendations for classification, prevention, monitoring, and dental management. Gen Dent. 2004;52:544–52. Vaughan CJ, Delanty N. Hypertensive emergencies. Lancet. 2000;356...

Abbreviations : Efficacy of intravenous sedation a...

Systolic blood pressure Diastolic blood pressure Pulse rate Rate pressure product Electrocardiogram Percutaneous oxygen saturation Analysis of variance Immediate-release

Conclusions : Efficacy of intravenous sedation and...

In this study, we showed that the stable hemodynamic was obtained by performing intravenous sedation and oral administration of nifedipine for patients with hypertension. It is important not only to understand the systemic management of the patient but also to obtain stabled hemodynamic by performing intravenous sedation and oral administration of nifedipine for patients with hypertension in order...

Discussion : Efficacy of intravenous sedation and ...

Implant surgery is performed in patients with a wide age range, including elderly patients with hypertension. Dentists or oral surgeons often encounter hypertensive patients who are undiagnosed or noncompliant. Among Japanese over the age of 30, 60% of men and 44.6% of women suffer from high blood pressure, and 33.8% of men and 25.6% of women with a history of hypertension have not been managed me...

Discussion : Efficacy of intravenous sedation and ...

For patients with stage 2 hypertension before operation, it is difficult to maintain the recommended blood pressure during surgery using only intravenous sedation, and it is necessary to decrease blood pressure by antihypertensive drugs. In this study, the blood pressure of patients with sustained hypertension was reduced to stage I hypertension about 30 min after administration of oral nifedipin...

Discussion : Efficacy of intravenous sedation and ...

In 44 (8.5%) of the 516 implant surgery cases, oral nifedipine had to be administered, since preoperative SBP was higher than 160 mmHg in these patients. Within 30 min of administration of nifedipine, SBP of hypertensive patients decreased to a similar range as that of hypertensive patients who did not need administration of oral nifedipine. Intravenous sedation after nifedipine administration t...

Results : Efficacy of intravenous sedation and ora...

In patients with oral nifedipine in the hypertensive group, the PR value slightly increased prior to initiation of intravenous sedation (p = 0.224) and then significantly decreased until completion of the operation (p 160 mmHg during and at completion of operation showed maximum SBP of 180 mmHg in the normotensive group, 190 mmHg on the hypertensive group without preoperative oral nifedip...

Results : Efficacy of intravenous sedation and ora...

Patient demographics and clinical characteristics are summarized in Table 1. There were significant differences in age (p 

Methods : Efficacy of intravenous sedation and ora...

This study protocol was approved by the ethics committee of Japanese Dental Society of Anesthesiology (No. 2015–4).

Methods : Efficacy of intravenous sedation and ora...

Following confirmation of a sufficient anesthetic effect, intravenous sedation with continuous infusion of propofol 1 to 2 mg/kg/h and midazolam 20 to 40 μg/kg bolus together with inhalation of oxygen 3 L/min via nasal cannula was initiated. After confirming Verrill sign, implant surgery was initiated. During operation, the propofol dose was adjusted to maintain the optimum conscious sedative ...

Methods : Efficacy of intravenous sedation and ora...

A retrospective review of the clinical records was conducted for 336 patients who received dental implant-related surgeries combined with intravenous sedation between January 2008 and February 2012 at our outpatient dental offices. Among the patients, 125 patients received multiple surgeries during the observation period: 4 patients underwent surgery five times, 7 patients four times, 29 patients ...

Background : Efficacy of intravenous sedation and ...

Osseointegrated dental implants were introduced in Japan in 1983, and the procedures are now performed very frequently. Dental implants are placed in a wide age range of patients, including elderly patients with hypertension. Patients with very high blood pressure are at great risk for acute medical problems when undergoing stressful dental procedures, such as oral surgery, periodontal surgery, an...

Abstract : Efficacy of intravenous sedation and or...

To examine the effects of intravenous sedation and oral nifedipine on blood pressure and pulse rate in patients with perioperative high blood pressure undergoing implant surgery, the clinical records of dental implant patients managed by intravenous sedation at our outpatient dental offices were retrospectively evaluated. A total of 516 clinical charts were evaluated. The subjects were divided in...

Figure 2. Results for all implants instrumented wi...

Figure 2. ture. Temperature rise at 30 s: bone level 3.3 mm > bone level 4.1 mm > Straumann regular neck 3.3 mm = Astra 3.5 mm = Straumann regular neck 4.8 mm. (b) Temperature rise when instrumenting with the Satelec ultrasonic device with cooling. The horizontal dotted line denotes the assumed critical rise in temperature. Temperature rise at 30 s: bone level 3.3 mm =...

Figure 1. Implant embedded in epoxy resin with the...

Figure 1. Implant embedded in epoxy resin with thermocouple at the outer surface. Figure 1. Implant embedded in epoxy resin with thermocouple at the outer surface.

About this article : Temperature rise during remov...

Meisberger, E.W., Bakker, S.J.G. & Cune, M.S. Temperature rise during removal of fractured components out of the implant body: an in vitro study comparing two ultrasonic devices and five implant types. Int J Implant Dent 1, 7 (2015). https://doi.org/10.1186/s40729-015-0008-0 Download citation Received: 19 December 2014 Accepted: 02 March 2015 Published: 20 March 2015 DOI: https://doi.org/10.1...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and in...

Additional information : Temperature rise during r...

This research was made possible by the support of the authors’ institutions. Eric W Meisberger, Sjoerd JG Bakker and Marco S Cune declare that they have no competing interests. EM and SB carried out the experiment. MC participated in the design of the study and performed the statistical analysis and helped to draft the manuscript. All authors read and approved the final manuscript.

Author information : Temperature rise during remov...

University Medical Center Groningen, Center for Dentistry and Oral Hygiene, Department of Fixed and Removable Prosthodontics and Biomaterials, The University of Groningen, Gebouw 3216, kamer 206, A. Deusinglaan 1, 9713 AV, Groningen, The Netherlands Eric W Meisberger, Sjoerd J G Bakker & Marco S Cune Department of Oral-Maxillofacial Surgery, Prosthodontics and Special Dental Care, St. Antoniu...

Acknowledgements : Temperature rise during removal...

The input of Prashant K. Sharma PhD, material scientist of the Department of Biomedical Engineering (Kolff Institute) of the UMC Groningen is greatly appreciated for his help interpreting the data. Michael Kars, DDS assisted during the collection of the data.

References : Temperature rise during removal of fr...

Satterthwaite JD, Stokes AN, Frankel NT. Potential for temperature change during application of ultrasonic vibration to intra-radicular posts. Eur J Prosthodont Restor Dent. 2003;11:51–6. Horan BB, Tordik PA, Imamura G, Goodell GG. Effect of dentin thickness on root surface temperature of teeth undergoing ultrasonic removal of posts. J Endod. 2008;34:453–5. Dominici JT, Clark S, Scheetz J, E...

References : Temperature rise during removal of fr...

Eriksson AR, Albrektsson T. Temperature threshold levels for heat-induced bone tissue injury: a vital-microscopic study in the rabbit. J Prosthet Dent. 1983;50:101–7. Benington IC, Biagioni PA, Briggs J, Sheridan S, Lamey PJ. Thermal changes observed at implant sites during internal and external irrigation. Clin Oral Implants Res. 2002;13:293–7. Li S, Chien S, Branemark PI. Heat shock-induce...

References : Temperature rise during removal of fr...

Assenza B, Tripodi D, Scarano A, Perrotti V, Piattelli A, Iezzi G, et al. Bacterial leakage in implants with different implant-abutment connections: an in vitro study. J Periodontol. 2011;83:491–7. Ha CY, Lim YJ, Kim MJ, Choi JH. The influence of abutment angulation on screw loosening of implants in the anterior maxilla. Int J Oral Maxillofac Implants. 2011;26:45–55. Spazzin AO, Henrique GE,...

References : Temperature rise during removal of fr...

Sailer I, Philipp A, Zembic A, Pjetursson BE, Hammerle CH, Zwahlen M. A systematic review of the performance of ceramic and metal implant abutments supporting fixed implant reconstructions. Clin Oral Implants Res. 2009;20 Suppl 4:4–31. Romeo E, Storelli S. Systematic review of the survival rate and the biological, technical, and aesthetic complications of fixed dental prostheses with cantilever...

Conclusions : Temperature rise during removal of f...

It is concluded from this in vitro study that heat accumulation and transfer is dependent on the type of ultrasonic device, the use of coolant, and the implant type. The highest rise in temperature is seen when using the Satelec device without coolant on the smaller diameter implants. The EMS device causes limited rise in temperature when used without coolant for less than 10 s, but presumably de...

Discussion : Temperature rise during removal of fr...

Cooling proves effective for both systems, increasing the outer implant temperature by an acceptable 1°C to 3°C during continued instrumentation; however, as already stated, the spray will blur the vision of the operator. One would expect the temperature to drop immediately after cessation of instrumentation and cooling, but the peak temperature is reached some seconds later for all experimenta...

Discussion : Temperature rise during removal of fr...

The degree to which a material is able to transfer heat is called thermal conductivity. It can be defined as the time rate of transfer by conduction, through unit thickness, across unit area for unit temperature gradient. Differences in design and wall thickness of the implants used in the present study account for the variation in outcome (i.e., Straumann tissue level 4.8 implant less effected), ...

Discussion : Temperature rise during removal of fr...

Several techniques have been described to deal with biomechanical complications. Acquiring adequate visibility and access is essential to success which will require the use of a dental microscope. Several mechanical approaches to remove screw remnants can be employed. Generally, after identifying the position and condition of the screw remnant, it can be carefully removed using manual instrumenta...

Results : Temperature rise during removal of fract...

The mean maximum rise in temperature (deltaTmax, all implants averaged per experimental condition) was reached at 30 to 40 s for all conditions. There was a significant difference for the Satelec device without cooling (mean 9.6, SD 1.6°C) and the EMS device without cooling (mean 4.3, SD 2.0°C) (t-test, t(28) = 4.7, p 

Results : Temperature rise during removal of fract...

The results for all implants instrumented with the two tested ultrasonic devices, either with or without cooling, are presented in Figure 2a,b,c,d. For the Satelec device, applied without coolant, only the temperature of the Straumann wide body regular neck implant never exceeded the 50 threshold. The data proved normally distributed (Kolmogorov-Smirnov test, p > 0.05). Analysis of variance ...

Methods : Temperature rise during removal of fract...

Two different types of commercially available ultrasonic devices, set at their lowest intensity for endodontic purpose, were used to instrument the internal portion of five different implant types, either with or without cooling. Intermittent anti-clockwise strokes were made, assuring that the tip was constantly in contact with the inner implant wall, as much as possible mimicking the motion that ...

Background : Temperature rise during removal of fr...

The use of ultrasonic equipment under adequate magnification may facilitate removal. It generates heat. Instrumentation without a coolant likely increases the temperature of the implant body and could cause tissue damage, in particular be harmful to osseointegration. The use of a coolant could be effective, but compromises visibility considerably, hence increases the risk of damaging the internal ...

Background : Temperature rise during removal of fr...

Complications in implant dentistry are generally divided into biological and mechanical complications. Mechanical complications include fracture of the implant body or prosthetic components such as chipping of ceramic material as well as loosening or fracture of implant abutments or fixation screws. This has a documented prevalence of 6 to 13% and 0.4 to 2% respectively after 5 years [1-7]. With...

Abstract : Temperature rise during removal of frac...

Ultrasonic instrumentation under magnification may facilitate mobilization of screw remnants but may induce heat trauma to surrounding bone. An increase of 5°C is considered detrimental to osseointegration. The objective of this investigation was to examine the rise in temperature of the outer implant body after 30 s of ultrasonic instrumentation to the inner part, in relation to implant type, t...

Figure 5. Flow diagram of CBCT imaging and measure...

Figure 5. Flow diagram of CBCT imaging and measurements to calculate bone thickness buccally of implants. Figure 5. Flow diagram of CBCT imaging and measurements to calculate bone thickness buccally of implants.

Figure 4. Implant measurements. Measurements wer...

Figure 4. Figure 4. Implant measurements. Measurements were performed at each millimeter along the axis of the implant for 5 mm, beginning at the neck of the implant.

Figure 3. Implant position. Due to the alienation ...

Figure 3. Implant position. Due to the alienation of the patients’ DICOM files by MIRIT, the exact position of the implant was defined. As such, the measurements could take place in the exact correct buccal direction. Figure 3. Implant position. Due to the alienation of the patients’ DICOM files by MIRIT, the exact position of the implant was defined. As such, the measurements could take ...

Figure 2. Conventional intra-oral radiograph of sa...

Figure 2. Conventional intra-oral radiograph of same patient with implant-supported restoration at position 21. Figure 2. Conventional intra-oral radiograph of same patient with implant-supported restoration at position 21.

Figure 1. Clinical photograph of implant-supported...

Figure 1. Clinical photograph of implant-supported restoration at position 21. Figure 1. Clinical photograph of implant-supported restoration at position 21.

About this article : Inter- and intraobserver repr...

Slagter, K.W., Raghoebar, G.M., Vissink, A. et al. Inter- and intraobserver reproducibility of buccal bone measurements at dental implants with cone beam computed tomography in the esthetic region. Int J Implant Dent 1, 8 (2015). https://doi.org/10.1186/s40729-015-0007-1 Download citation Received: 24 December 2014 Accepted: 19 February 2015 Published: 18 April 2015 DOI: https://doi.org/10.11...

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Additional information : Inter- and intraobserver ...

Kirsten W. Slagter, Gerry M. Raghoebar, Arjan Vissink, Henny JA. Meijer declare that they have no competing interests. KWS, GMR, AV, and HJAM provided substantial contributions to the conception or design of the work, or the acquisition, analysis, or interpretation of data for the work; drafted the paper or revised it critically; gave final approval of the version to be published; and agreed to b...

Author information : Inter- and intraobserver repr...

Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, The Netherlands Kirsten W Slagter, Gerry M Raghoebar, Arjan Vissink & Henny J A Meijer Department of Fixed and Removable Prosthodontics, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700RB, Groningen, The Netherlands He...

References : Inter- and intraobserver reproducibil...

Miyamoto Y, Obama T. Dental cone beam computed tomography analyses of postoperative labial bone thickness in maxillary anterior implants: comparing immediate and delayed implant placement. Int J Periodontics Restorative Dent. 2011;31:215–25. Kamburoglu K, Murat S, Kilic C, Yuksel S, Avsever H, Farman A, et al. Accuracy of CBCT images in the assessment of buccal marginal alveolar peri-implant de...

References : Inter- and intraobserver reproducibil...

Den Hartog L, Slater JJ, Vissink A, Meijer HJ, Raghoebar GM. Treatment outcome of immediate, early and conventional single-tooth implants in the aesthetic zone: a systematic review to survival, bone level, soft-tissue, aesthetics and patient satisfaction. J Clin Periodontol. 2008;35:1073–86. De Rouck T, Collys K, Cosyn J. Single-tooth replacement in the anterior maxilla by means of immediate im...

Abbreviations : Inter- and intraobserver reproduci...

three-dimensional cone beam computed tomography computerized tomography Digital Imaging and Communications in Medicine field of view Hounsfield unit Multimodality Image Registration using Information Theory

Conclusions : Inter- and intraobserver reproducibi...

When applying 3D image-based software programs according to the set-up used in this study, CBCTs are suitable for reliable and reproducible measurements of buccal bone thickness at implants.

Discussion : Inter- and intraobserver reproducibil...

Intraobserver and interobserver agreement was very high with measurements on CBCTs of bone buccally of dental implants. Apparently, the method is clear and measurements can be performed reproducibly. Moreover, measurements are not observer dependent, meaning that results of different observers in different studies can be compared with each other. In previous studies, buccal bone thickness was als...

Results : Inter- and intraobserver reproducibility...

The mean buccal bone thickness measured by observers 1 and 2 was 2.42 mm (sd: 0.50) and 2.41 mm (sd: 0.47), respectively. Interobserver intraclass correlation coefficient was 0.96 (95% CI 0.93 to 0.98). The mean buccal bone thickness of the first measurement and the second measurement of observer 1 was 2.42 mm (sd: 0.50) and 2.53 mm (sd: 0.49), respectively, with an intraobserver intraclass co...

Methods : Inter- and intraobserver reproducibility...

The implant and patient dataset were exactly aligned by the MIRIT method, so that the distance from the central axis of the implant to the outer contour of the buccal bone could be measured. Area of interest was the upper 5 mm section of the implant, beginning at the neck of the implant towards the apical direction. Exact dimensions along the implant axis of each implant configuration used in the...

Methods : Inter- and intraobserver reproducibility...

Ten patients with a dental implant in the esthetic zone (regions 13 to 23) were included (Figures 1 and 2). Research was carried out in compliance with the Helsinki Declaration. Patients were part of a randomized controlled trial on esthetics; the study was approved by the Medical Ethic Board of the University Medical Center Groningen, University of Groningen (METC 2010.246) as well as that writt...

Background : Inter- and intraobserver reproducibil...

Single-tooth implant placement in the esthetic zone is a highly reliable treatment option for replacing a failing tooth [1-4]. Yet, research interest has shifted from implant survival towards optimal preservation of soft and hard tissues [5-7]. Especially in the esthetic region, buccal bone and its preservation is one of the key factors in esthetic outcome [8]. Computerized tomography (CT) scans ...

Abstract : Inter- and intraobserver reproducibilit...

Sufficient buccal bone is important for optimal esthetic results of implant treatment in the anterior region. It can be measured with cone beam computed tomography (CBCT), but background scattering and problems with standardization of the measurements are encountered. The aim was to develop a method for reliable, reproducible measurements on CBCTs. Using a new method, buccal bone thickness was me...

Table 5 Bacterial and fu...

Patient M. salivarium V. parvula S. aureus P. gingivalis P. micra T. forsythia Fungal organisms 1 7.05E + 01 7.00E + 01 - ...

Table 4 Bacterial and fu...

Patient M. salivarium V. parvula S. aureus P. gingivalis P. micra T. forsythia Fungal organisms 1 - 2.26E + 03 - 1...

Table 3 Bacterial and fu...

Patient Severity M. salivarium V. parvula S. aureus P. gingivalis P. micra T. forsythia Fungal organisms 1 i-m - 7.96E + 04 ...

Table 2 Overview of fung...

Species Gene Primer/probe Sequences (5′-3′) Aspergillus spp. plus ITS2 aspe-F CTG TCC GAG CGT CAT TG Penicillium spp.   pen1-F ...

Table 1 Overview of bact...

Species Gene Primer/probe Sequences (5′-3′) Mycoplasma salivarium rpoB msali-F CCG TCA AAT GAT TTC GAT TGC    msali-R GAA CTG CTT GAC GTT GCA TGT T ...

About this article : Real-time PCR analysis of fun...

Schwarz, F., Becker, K., Rahn, S. et al. Real-time PCR analysis of fungal organisms and bacterial species at peri-implantitis sites. Int J Implant Dent 1, 9 (2015). https://doi.org/10.1186/s40729-015-0010-6 Download citation Received: 16 January 2015 Accepted: 11 March 2015 Published: 21 April 2015 DOI: https://doi.org/10.1186/s40729-015-0010-6

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Frank Schwarz, Kathrin Becker, Sebastian Rahn, Andrea Hegewald, Klaus Pfeffer, and Birgit Henrich declare that they have no competing interests. FS, BH, and KP have made substantial contributions to study conception and design, analysis, and interpretation of data as well as manuscript preparation. KB performed the statistical analysis. AH and SR were involved in data acquisition. All authors rea...

Author information : Real-time PCR analysis of fun...

Department of Oral Surgery, Westdeutsche Kieferklinik, Heinrich Heine University, Moorenstraße 5, D-40225, Düsseldorf, Germany Frank Schwarz & Andrea Hegewald Department of Orthodontics, Westdeutsche Kieferklinik, Heinrich Heine University, Moorenstraße 5, D-40225, Düsseldorf, Germany Kathrin Becker Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Univer...

Acknowledgements : Real-time PCR analysis of funga...

We kindly appreciate the skills and commitment of Ms. Dana Belick (Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University, Düsseldorf) in the DNA preparation and bacterial analysis and the Jürgen Manchot Foundation for financial support.

References : Real-time PCR analysis of fungal orga...

Hultin M, Gustafsson A, Hallstrom H, Johansson LA, Ekfeldt A, Klinge B. Microbiological findings and host response in patients with peri-implantitis. Clin Oral Implants Res. 2002;13:349–58. Engel LD, Kenny GE. Mycoplasma salivarium in human gingival sulci. J Periodontal Res. 1970;5:163–71. Jarvensivu A, Hietanen J, Rautemaa R, Sorsa T, Richardson M. Candida yeasts in chronic periodontitis ti...

References : Real-time PCR analysis of fungal orga...

McDonald RR, Antonishyn NA, Hansen T, Snook LA, Nagle E, Mulvey MR, et al. Development of a triplex real-time PCR assay for detection of Panton-Valentine leukocidin toxin genes in clinical isolates of methicillin-resistant Staphylococcus aureus. J Clin Microbiol. 2005;43:6147–9. Morillo JM, Lau L, Sanz M, Herrera D, Martin C, Silva A. Quantitative real-time polymerase chain reaction based on si...

References : Real-time PCR analysis of fungal orga...

Lindhe J, Meyle J, Group DoEWoP. Peri-implant diseases: consensus report of the sixth European workshop on periodontology. J Clin Periodontol. 2008;35:282–5. Mombelli A, Decaillet F. The characteristics of biofilms in peri-implant disease. J Clin Periodontol. 2011;38 Suppl 11:203–13. Heitz-Mayfield LJ. Peri-implant diseases: diagnosis and risk indicators. J Clin Periodontol. 2008;35:292–30...

Abbreviations : Real-time PCR analysis of fungal o...

Bleeding on probing Mycoplasma salivarium Porphyromonas gingivalis Parvimonas micra Probing pocket depth Staphylococcus aureus Tannerella forsythia Veillonella parvula

Conclusions : Real-time PCR analysis of fungal org...

Within the limitations of the present analysis, it was concluded that Candida spp. and other fungal organisms were frequently identified at peri-implantitis as well as healthy implant sites and co-colonized with P. micra and T. forsythia.

Discussion : Real-time PCR analysis of fungal orga...

Furthermore, the present analysis failed to identify any significant correlation of either fungal organisms or disease severity with opportunistic bacteria, such as M. salivarium, V. parvula, and S. aureus. At tooth sites, M. salivarium was mainly isolated from the sulcus area and associated with gingivitis lesions [27]. Interestingly, S. aureus has only been identified at one single peri-implanti...

Discussion : Real-time PCR analysis of fungal orga...

The present study aimed at analyzing and correlating fungal organisms with several periodontopathogenic and opportunistic bacterial species at peri-implantitis sites using real-time PCR. These outcomes were compared with those noted at healthy implant sites as well as teeth with a history of periodontitis. Basically, the present analysis has pointed to a high prevalence of fungal organisms in sub...

Results : Real-time PCR analysis of fungal organis...

The Kendall-Tau-b coefficients failed to reveal any significant correlations between the presence of fungal organisms and the proportions of M. salivarium (0.25), V. parvula (0.34), P. gingivalis (0.60), P. micra (0.32), T. forsythia (0.12), and S. aureus (0.66) (P > 0.05, respectively).

Results : Real-time PCR analysis of fungal organis...

According to the given definition, the present analysis was based on a total of n = 13 initial to moderate and n = 6 advanced peri-implantitis lesions (n = 19 patients), 10 healthy implant sites (n = 10 patients), as well as 10 teeth with a history of periodontitis (n = 10 out of 19 patients suffering from peri-implantitis). The analysis of fungal organisms as well as of M. sa...

Methods : Real-time PCR analysis of fungal organis...

The statistical analysis was performed using a commercially available software program (SPSS Statistics 22.0, IBM Corp., Ehningen, Germany). Kendall-Tau-b correlation coefficients were calculated to evaluate the dependence between fungal organisms, bacterial species as well as disease severity (i.e., initial to moderate and advanced sites). Results were considered statistically significant at P 

Methods : Real-time PCR analysis of fungal organis...

In the peri-implantitis group, one additional subgingival plaque sample was obtained from partially edentulous patients with a history of periodontitis (n = 10) and obtained at a tooth exhibiting the highest PD but no signs of acute periodontal disease (i.e., BOP/no suppuration). None of these teeth were located adjacent to the sampled implant sites. The control samples were also prepared for ...

Methods : Real-time PCR analysis of fungal organis...

A total of 29 partially or fully edentulous patients were consecutively recruited from the Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany, between April 2013 and July 2014. Nineteen patients (7 men and 13 women; mean age 58.8 ± 12.6 years) suffered from initial to moderate or advanced peri-implantitis, while ten patients (6 men and 4 women; mean age 55.2 ± 1...

Background : Real-time PCR analysis of fungal orga...

There is considerable evidence supporting the view that peri-implant diseases are infectious in nature and mainly linked to an uncontrolled accumulation of bacterial plaque biofilms [1]. Basically, diseased implant sites are dominated by gram-negative anaerobic bacteria and therefore feature microbiological characteristics similar to those noted for chronic periodontal infections [2]. Even though ...

Abstract : Real-time PCR analysis of fungal organi...

The potential role of fungal organisms and their co-aggregation with either periodontopathogens or opportunistic pathogens at peri-implantitis sites is unknown. The aim of the present study was to qualitatively/quantitatively analyze and correlate fungal organisms and bacterial species at peri-implantitis sites. In a total of 29 patients, submucosal/subgingival plaque samples were collected at pe...

Fig. 3. Postoperative radiograph of the resected d...

Fig. 3. Postoperative radiograph of the resected dental implant in the right anterior maxilla Fig. 3. Postoperative radiograph of the resected dental implant in the right anterior maxilla

Fig. 2. On radiological examination, it was confir...

Fig. 2. On radiological examination, it was confirmed that the dental implant had perforated the cortical bone of the right nasal floor Fig. 2. On radiological examination, it was confirmed that the dental implant had perforated the cortical bone of the right nasal floor

Fig. 1. On anterior rhinoscopy, the apical part of...

Fig. 1. On anterior rhinoscopy, the apical part of the titanium dental implant in the right anterior maxilla was seen in the nasal floor close to the nasal septum Fig. 1. On anterior rhinoscopy, the apical part of the titanium dental implant in the right anterior maxilla was seen in the nasal floor close to the nasal septum

About this article : Altered nasal airflow: an unu...

Wolff, J., Karagozoglu, K.H., Bretschneider, J.H. et al. Altered nasal airflow: an unusual complication following implant surgery in the anterior maxilla. Int J Implant Dent 2, 6 (2016). https://doi.org/10.1186/s40729-016-0045-3 Download citation Received: 24 August 2015 Accepted: 23 March 2016 Published: 29 March 2016 DOI: https://doi.org/10.1186/s40729-016-0045-3

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : Altered nasal airflow: an...

Jan Wolff, Hakki Karagozoglu, Jochen Bretschneider, Tymour Forouzanfar, and Engelbert Schulten declare that they have no competing interests. JW gave substantial contributions to the conception or design of the work, drafted the work, and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately i...

Author information : Altered nasal airflow: an unu...

Department of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center/Academic Centre for Dentistry Amsterdam (ACTA), Amsterdam, The Netherlands Jan Wolff, K. Hakki Karagozoglu, Tymour Forouzanfar & Engelbert A. J. M. Schulten Department of Otorhinolaryngology-Head and Neck Surgery, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands Jochen H...

References : Altered nasal airflow: an unusual com...

Esposito M, Grusovin MG, Kwan S, et al. Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment. Cochrane Database Syst Rev. 2008;16:CD003607. Raghoebar GM, van Weissenbruch R, Vissink A. Rhino-sinusitis related to endosseous implants extending into the nasal cavity. A case report. Int J Oral Maxillofac Surg. 2004;33:312–4. Zimbler MS, Lebowitz RA, ...

Consent : Altered nasal airflow: an unusual compli...

Since this is a case report, no approval of the Institutional Review Board was necessary. Written informed consent was obtained from the patient for publication of this Case report and any accompanying images

Conclusions : Altered nasal airflow: an unusual co...

In conclusion, dental implants protruding into the nasal cavity can cause alterations to the airflow. Dental implants partially residing in the nasal cavity can be minimal invasively treated by sectioning the apical part of the implant using a transnasal approach.

Case presentation : Altered nasal airflow: an unus...

No complications were apparent during the surgical procedure. Postoperative clinical and radiological examinations demonstrated an intact nasal mucosa and an adequate resection of the dental implant to the level of the nasal floor (Fig. 3). The patient had an uneventful recovery and at 2-, 6-, and 12-month follow-up, she reported having no altered nasal airflow. Insertion of endosseous dental im...

Case presentation : Altered nasal airflow: an unus...

A 50-year-old female patient was referred to the Department of Oral and Maxillofacial Surgery of the VU University Medical Center in Amsterdam with complaints of a long ongoing unpleasant altered nasal airflow after the placement of eight dental implants in the maxilla. Four months prior to implant surgery, a bony augmentation of the atrophic edentulous alveolar crest and a bilateral maxillary sin...

Background : Altered nasal airflow: an unusual com...

Endosseous dental implants are commonly used to rehabilitate fully or partially edentulous patients [1]. The insertion of such implants can in some cases cause complications, especially in the edentulous atrophic maxilla [2–4]. In this paper, an unusual complication of altered nasal airflow after the placement of an endosseous dental implant in the maxilla is presented. Subsequent treatment of t...

Abstract : Altered nasal airflow: an unusual compl...

Dental implants have been in routine clinical use for over three decades and are a predictable treatment modality. However, as with all other aspects of dentistry, complications occur. A 50-year-old female patient with complaints of a long ongoing unpleasant altered nasal airflow presented herself at the VU University Medical Center Amsterdam. Visual inspection of the right nasal cavity revealed t...

Fig. 7. The epithesis allows both prompt inspectio...

Fig. 7. The epithesis allows both prompt inspection of the resection site and makes daily care easier Fig. 7. The epithesis allows both prompt inspection of the resection site and makes daily care easier

Fig. 6. Frontal view of the patient after superior...

Fig. 6. Frontal view of the patient after superior overdenture and nasal prosthesis delivery Fig. 6. Frontal view of the patient after superior overdenture and nasal prosthesis delivery

Fig. 5. The intraoral bar crossing the palatal def...

Fig. 5. The intraoral bar crossing the palatal defect arising the nasal understructure Fig. 5. The intraoral bar crossing the palatal defect arising the nasal understructure

Fig. 4. A front view of the bar with the intraoral...

Fig. 4. A front view of the bar with the intraoral portion and the metal extension for epithesis attachment Fig. 4. A front view of the bar with the intraoral portion and the metal extension for epithesis attachment

Fig. 3. Postoperative panorex showing the symmetri...

Fig. 3. Postoperative panorex showing the symmetric distribution of the fixtures Fig. 3. Postoperative panorex showing the symmetric distribution of the fixtures

Fig. 2. The healing abutments positioned onto fixt...

Fig. 2. The healing abutments positioned onto fixtures and the oronasal communication Fig. 2. The healing abutments positioned onto fixtures and the oronasal communication

Fig. 1. Intraoperative view of the zygoma implants...

Fig. 1. Intraoperative view of the zygoma implants placed in the residual maxilla Fig. 1. Intraoperative view of the zygoma implants placed in the residual maxilla

About this article : Rehabilitation of a complex m...

Trevisiol, L., Procacci, P., D’Agostino, A. et al. Rehabilitation of a complex midfacial defect by means of a zygoma-implant-supported prosthesis and nasal epithesis: a novel technique. Int J Implant Dent 2, 7 (2016). https://doi.org/10.1186/s40729-016-0043-5 Download citation Received: 22 July 2015 Accepted: 23 March 2016 Published: 01 April 2016 DOI: https://doi.org/1...

Rights and permissions : Rehabilitation of a compl...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : Rehabilitation of a compl...

Francesca Ferrari, Pasquale Procacci, Lorenzo Trevisiol, Pier Francesco Nocini, Daniele De Santis and Antonio D’Agostino declare that they have no competing interests. FF was involved in revising the manuscript critically. PP was involved in drafting the manuscript. LT is another surgeon that belongs to surgery equipment. PFN, head professor and surgeon, operated the patient. DDeS was involved ...

Author information : Rehabilitation of a complex m...

Department of Surgery, Section of Oral and Maxillofacial Surgery, University of Verona, Policlinico “Giovanni Battista Rossi”, Piazzale Ludovico Antonio Scuro, 10, 37134, Verona, Italy Lorenzo Trevisiol, Pasquale Procacci, Antonio D’Agostino, Francesca Ferrari, Daniele De Santis & Pier Francesco Nocini You can also search for this author in PubMed Google Sch...

References : Rehabilitation of a complex midfacial...

Karakoca S, Aydin C, Handan Y, Bal BT. Retrospective study of treatment outcomes with implant- retained extraoral prostheses: survival rates and prosthetic complications. J Prosthet Dent. 2010;103:118–26. Download references

References : Rehabilitation of a complex midfacial...

Parel SM, Branemark PI, Ohrnell LO, Svensson B. Remote implant anchorage for the rehabilitation of maxillary defects. J Prosthet Dent. 2001;86:377–81. Bowden JR, Flood TR, Downie IP. Zygomaticus implants for retention of nasal prostheses after rhinectomy. Br J Oral Maxillofac Surg. 2006;44:54–6. D’Agostino A, Procacci P, Ferrari F, Trevisiol L, Nocini PF. Zygoma implant-supported prostheti...

Consent : Rehabilitation of a complex midfacial de...

Written informed consent was obtained from the patient for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.

Conclusions : Rehabilitation of a complex midfacia...

Implant-supported prosthesis is a valid method to restore resected oral and head cancer patients and offers a good chance to social reintegration. The aesthetic result and facial camouflage are more achievable by means of dentures and epithesis than with several reconstructive interventions. Furthermore, due to the high risk of recurrences, it is sometime mandatory to keep the defect inspectionabl...

Case presentation : Rehabilitation of a complex mi...

Rethinking globally of the possible indications to the adoption of this technique and its advantages compared to reconstructive microsurgery, the use of zygoma-implant-supported prosthesis may be suitable for patients whose systemic conditions are poor. The duration of surgery and of the postoperative recovery would be remarkably shortened avoiding the complications related to the harvesting of a ...

Case presentation : Rehabilitation of a complex mi...

As far as prosthetic design is concerned, it is mandatory to avoid or, if not possible, limit as much as possible distal cantilever: given the absence of the premaxilla, an anterior cantilever is already present. Implant splintage is recommended [1, 8], and the bar design must respect technical data (implant-to-implant distance, cross-arch stabilization avoiding to cover oronasal communication and...

Case presentation : Rehabilitation of a complex mi...

Patients with advanced orofacial cancer may require extensive surgical resection; the wider and more evident is the amputated region, the more this condition is generating inability for patients [6]. Visible head site mutilation and functional impairment in speech prevent social reintegration, and abnormal self-perception leads patients to depression [6]. Even if modern surgery offers many techni...

Case presentation : Rehabilitation of a complex mi...

Cortical steroids were administered for the first two postoperative days. A postoperative 10-day cycle of antibiotic therapy (amoxicillin 1000 mg TID) was administered. Analgesics were administered as required. Sutures were removed 15 days after surgery. A soft diet was recommended for the first 2 weeks. Three months afterwards, healing abutments were connected (Fig. 2) [4]. Approximately 4...

Case presentation : Rehabilitation of a complex mi...

The patient, a male 46 years old at the time of our visit, underwent surgical resection of nasal pyramid and premaxilla including the whole upper jaw teeth sparing nasal bones. When the patient came to our clinic, apart from the defect resulting from the resection, he presented with a retraction scar crossing the upper lip from the floor of the nasal defect through the filtrum. The surgical resec...

Background : Rehabilitation of a complex midfacial...

The use of zygoma implants in the rehabilitation of patients who underwent surgical resection for oral cancer has been widely described [1–3]. There are several possibilities that can be considered when evaluating the possibility of surgical reconstruction after the first cancer resection, such as microvascular free flaps or rotation flaps, but it is sometimes necessary to monitor the healing pr...

Abstract : Rehabilitation of a complex midfacial d...

Several authors have described zygoma implants as a reliable surgical option to rehabilitate severe maxillary defects in case of extreme atrophy or oncological resections. The aim of this study is to report a new technical approach to the rehabilitation of a complex oronasal defect by means of a zygoma-implant-supported full-arch dental prosthesis combined with a nasal epithesis. The patient pres...

Table 2 Included literature : Dental implants in p...

Implant Author Year Reference Study type Patients Primary disease in BP patients (n) ...

Table 1 PubMed literature search with the total nu...

Topic Identified (n) Included (n) Outcome osteonecrosis risk. ST (bisphosphonate OR denosumab) AND osteonecrosis jaw AND  ...

About this article : Dental implants in patients t...

Walter, C., Al-Nawas, B., Wolff, T. et al. Dental implants in patients treated with antiresorptive medication – a systematic literature review. Int J Implant Dent 2, 9 (2016). https://doi.org/10.1186/s40729-016-0041-7 Download citation Received: 26 September 2015 Accepted: 23 March 2016 Published: 04 April 2016 DOI: https://doi.org/10.1186/s40729-016-0041-7

Rights and permissions : Dental implants in patien...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : Dental implants in patien...

The authors Christian Walter, Bilal Al-Nawas, Tim Wolff, Eik Schiegnitz, and Knut A. Grötz declare that they have no competing interests. All authors designed the review. TW made the primary literature acquisition that was evaluated by the other others. All authors interpreted the data. CW drafted the manuscript that was revised by the other authors. All authors read and approved the final manus...

Author information : Dental implants in patients t...

Department of Oral and Maxillofacial Surgery – Plastic Surgery of the Johannes Gutenberg-University Mainz, Augustusplatz 2, 55131, Mainz, Germany Christian Walter, Bilal Al-Nawas & Eik Schiegnitz Department of Oral and Maxillofacial Surgery of the Dr. Horst Schmidt Clinic, Ludwig-Erhard-Str. 100, 65199, Wiesbaden, Germany Tim Wolff & Knut A. Grötz You can also search for this author in...

References : Dental implants in patients treated w...

Krimmel M, Ripperger J, Hairass M, Hoefert S, Kluba S, Reinert S. Does dental and oral health influence the development and course of bisphosphonate-related osteonecrosis of the jaws (BRONJ)? Oral Maxillofac Surg. 2014;18(2):213–8. doi:10.1007/s10006-013-0408-3. Tsao C, Darby I, Ebeling PR, Walsh K, O'Brien-Simpson N, Reynolds E, et al. Oral health risk factors for bisphosphonate-associated jaw...

References : Dental implants in patients treated w...

DeBaz C, Hahn J, Lang L, Palomo L. Dental Implant Supported Restorations Improve Quality of Life in Osteoporotic Women. Int J Dent. 2015;2015:451923. doi:10.1155/2015/451923. Grötz KA, Al-Nawas B. Persisting alveolar sockets-a radiologic symptom of BP-ONJ? J Oral Maxillofac Surg. 2006;64(10):1571–2. doi:10.1016/j.joms.2006.05.041. Hutchinson M, O'Ryan F, Chavez V, Lathon PV, Sanchez G, Hatche...

References : Dental implants in patients treated w...

Carmagnola D, Celestino S, Abati S. Dental and periodontal history of oncologic patients on parenteral bisphosphonates with or without osteonecrosis of the jaws: a pilot study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(6):e10–5. doi:10.1016/j.tripleo.2008.07.011. Jabbour Z, El-Hakim M, Mesbah-Ardakani P, Henderson JE, Albuquerque Jr R. The outcomes of conservative and surgical ...

References : Dental implants in patients treated w...

Marx RE, Sawatari Y, Fortin M, Broumand V. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws: risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg. 2005;63(11):1567–75. doi:10.1016/j.joms.2005.07.010. Al-Sabbagh M, Robinson FG, Romanos G, Thomas MV. Osteoporosis and bisphosphonate-related osteonecrosis in a dental school implant patient popula...

References : Dental implants in patients treated w...

Javed F, Almas K. Osseointegration of dental implants in patients undergoing bisphosphonate treatment: a literature review. J Periodontol. 2010;81(4):479–84. doi:10.1902/jop.2009.090587. Bedogni A, Bettini G, Totola A, Saia G, Nocini PF. Oral bisphosphonate-associated osteonecrosis of the jaw after implant surgery: a case report and literature review. J Oral Maxillofac Surg. 2010;68(7):1662–6...

References : Dental implants in patients treated w...

Grötz KA, Piesold JU, Al-Nawas B. Bisphosphonat-assoziierte Kiefernekrose (BP-ONJ) und andere Medikamenten-assoziierte Kiefernekrosen. 2012. AWMF online. Walter C, Al-Nawas B, Frickhofen N, Gamm H, Beck J, Reinsch L, et al. Prevalence of bisphosphonate associated osteonecrosis of the jaws in multiple myeloma patients. Head Face Med. 2010;6:11. doi:10.1186/1746-160X-6-11. Walter C, Sagheb K, Bit...

Abbreviations : Dental implants in patients treate...

bisphosphonate bisphosphonate-associated osteonecrosis of the jaws C-terminal telopeptide of the type I collagen patients intervention control outcome preferred reporting items for systematic reviews and meta-analyses protocols quality of life search term temporomandibular joint

Conclusions : Dental implants in patients treated ...

Successful implant therapy is feasible in patients receiving antiresorptive therapy. The risk of osteonecrosis development needs to be explained to the patient. An individual risk assessment is essential, taking the primary disease with the medication and further wound-healing-compromising diseases and medications into account. If possible, bone augmentations should be avoided, and a perioperative...

Discussion : Dental implants in patients treated w...

The use of bone markers is discussed controversially in the literature, and no clear recommendation can be given at the moment [1, 8]. In these cases, where an implant is planned, a perioperative antimicrobial prophylaxis should be administered, similar to the prophylaxis suggested in other surgical procedures performed in these patients, since this seems to be a tool to decrease BP-ONJ frequency ...

Discussion : Dental implants in patients treated w...

Dental implants can improve the Qol in patients with antiresorptive therapy (bisphosphonate/denosumab) [44] analogous to patients without antiresorptive therapy [48]. A recently performed systematic review on masticatory performance, bite force, nutritional state and patient’s satisfaction showed that implant-supported dentures were associated with high patient satisfaction regarding denture com...

Discussion : Dental implants in patients treated w...

Even latest guidelines and statements dealing with medication associated osteonecrosis of the jaws such as the American [7, 8], Scottish [47], Swiss [6] or German [1] do not address implant therapy in these patients in detail. Due to this lack of data a systematic literature review was performed to fill this gap. Unfortunately the literature dealing with this topic is very sparse and consists main...

Results : Dental implants in patients treated with...

No articles could be found regarding the prognosis of the remaining dentition depending on implant therapy, neither for patients with bisphosphonate nor denosumab treatment. There are no reliable parameters indicating the success of implants in patients with anti-resorptive therapy. The risk of osteonecrosis development has already been described in the chapter referring to the osteonecrosis risk...

Results : Dental implants in patients treated with...

The literature dealing with this topic can be separated into two groups: BP-ONJ case series for which varying amounts are caused by dentures in patients with malignant and benign diseases [2, 33–42] and studies performed on BP patients with dentures analyzing the frequency of BP-ONJ [15, 43]. Here as well, no imbalance regarding the dignity of the primary disease could be found. Jabbour descr...

Results : Dental implants in patients treated with...

Out of 606 articles 556 articles were excluded because they were either duplicates, case reports, narrative reviews, case series with less than 5 cases or were not associated with the topic at all (Table 1 and Fig. 1). Some of the articles analyzed more than one outcome and are referred to several times. Since the available literature is very inhomogeneous with a low level of evidence a statisti...

Review : Dental implants in patients treated with ...

A table was generated and used to collect the relevant information.

Review : Dental implants in patients treated with ...

A systematic review was performed in accordance with the preferred reporting items for systematic reviews and meta-analyses protocols (PRISMA-P), The review was performed using the PICO design. Patients: For which subclientel of patients with antiresorptive therapy Intervention: do dental implants have a benefit Control: compared to forgoing dental implants Outcome: in regards to oral rehabil...

Introduction : Dental implants in patients treated...

A similar scenario is well known in patients with radiation of the jaws. Initially, radiation therapy was seen as a contraindication for implant insertion [14] because of osteoradionecrosis. In Germany meanwhile, implants are covered by the health insurance by law in some of these patients (§28 SGB V Sozialgesetzbuch). Due to xerostomia sufficient fixation of a denture is rather complicated, and ...

Introduction : Dental implants in patients treated...

Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is a well-known side effect in patients receiving bisphosphonates (BP) due to e.g. osteoporosis, multiple myeloma or malignant diseases with metastases to the bone; prevalences range between 0.1% for patients with primary osteoporosis to 1% in patients with secondary osteoporosis and up to about 20% for special high risk subpopulations o...

Abstract : Dental implants in patients treated wit...

Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is triggered by inflammatory processes. Typical trigger factors are periodontal disease, denture pressure sores, and surgical interventions such as tooth extractions. Unfortunately there is only little data on how to proceed with implant therapy in patients with bisphosphonate treatment. This topic is not addressed in the German guidelin...

Fig. 6. a Panoramic X-ray image 1 year after the ...

Fig. 6. a Panoramic X-ray image 1 year after the surgery. b Intraoral photo 1 year after the surgery Fig. 6. a Panoramic X-ray image 1 year after the surgery. b Intraoral photo 1 year after the surgery

Fig. 5. Histopathologic photo of the resected mand...

Fig. 5. Histopathologic photo of the resected mandible (H-E staining) Fig. 5. Histopathologic photo of the resected mandible (H-E staining)

Fig. 4. a Intraoperative photo. The affected left ...

gmentally resected. b Intraoperative photo. A vascularized fibula bone graft. c Resected mandible. d Panoramic X-ray image after the surgery Fig. 4. a Intraoperative photo. The affected left mandible was segmentally resected. b Intraoperative photo. A vascularized fibula bone graft. c Resected mandible. d Panoramic X-ray image after the surgery

Fig. 3. CT images of the left mandible. a Axial vi...

Fig. 3. CT images of the left mandible. a Axial view at the left first molar. b Coronal view at the left first molar Fig. 3. CT images of the left mandible. a Axial view at the left first molar. b Coronal view at the left first molar

Fig. 2. Panoramic X-ray image at the first visit :...

Fig. 2. Panoramic X-ray image at the first visit Fig. 2. Panoramic X-ray image at the first visit

Fig. 1. Intraoral photo at the first visit : A cas...

Fig. 1. Intraoral photo at the first visit Fig. 1. Intraoral photo at the first visit

About this article : A case of peri-implantitis an...

Teramoto, Y., Kurita, H., Kamata, T. et al. A case of peri-implantitis and osteoradionecrosis arising around dental implants placed before radiation therapy. Int J Implant Dent 2, 11 (2016). https://doi.org/10.1186/s40729-016-0039-1 Download citation Received: 01 August 2015 Accepted: 21 March 2016 Published: 05 April 2016 DOI: https://doi.org/10.1186/s40729-016-0039-1

Rights and permissions : A case of peri-implantiti...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : A case of peri-implantiti...

Yuji Teramoto, Hiroshi Kurita, Takahiro Kamata, Hitoshi Aizawa, Nobuhiko Yoshimura, Humihiro Nishimaki, Kazunobu Takamizawa declare that they have no competing interests. All authors read and approved the final manuscript.

Author information : A case of peri-implantitis an...

Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, 3-1-1, Asahi, Matsumoto, 390-8621, Japan Yuji Teramoto, Hiroshi Kurita, Takahiro Kamata, Hitoshi Aizawa, Nobuhiko Yoshimura, Humihiro Nishimaki & Kazunobu Takamizawa You can also search for this author in PubMed Google Scholar You can also search for this author in ...

References : A case of peri-implantitis and osteor...

O'Dell K, Sinha U. Osteoradionecrosis. Oral Maxillofac Surg Clin North Am. 2011;23(3):455–64. Madrid C, Abarca M, Bouferrache K. Osteoradionecrosis: an update. Oral Oncol. 2010;46(6):471–4. Jacobson AS, Buchbinder D, Hu K, Urken ML. Paradigm shifts in the management of osteoradionecrosis of the mandible. Oral Oncol. 2010;46(11):795–801. Ozen J, Dirican B, Oysul K, Beyzadeoglu M, Ucok O, B...

Consent : A case of peri-i...

Written informed consent was obtained from the patient for the publication of this report and any accompanying images.

Conclusions : A case of peri-implantitis and osteo...

Dental implants have become increasingly popular, and a considerable number of people have undergone dental restorations using dental implants. Therefore, there will be an increasing probability of patients with dental implants receiving irradiation around their implants. Further studies are required to analyze whether dental implants located in the radiation field cause adverse effects in the lon...

Case presentation : A case of peri-implantitis and...

Secondarily, infection associated with dental implant may become a possible cause of ORN. In radiotherapy including the oral cavity, gingivitis is frequently observed adjacent to fixed metal dental restorations because they cause significant dose enhancement around them [12]. It is easy to speculate that the same occurs around dental implant prostheses (peri-implant mucositis). The presence of muc...

Case presentation : A case of peri-implantitis and...

In this paper, we reported a case of ORN arising around dental implants placed before radiotherapy. This is the third such case report to be published. Granström et al. reported three cases of ORN developing around dental implants previously placed for skin-penetrating prosthesis [8]. Slama et al. reported a case of mandibular ORN in post-implant radiation [9]. In these cases, the presence of den...

Case presentation : A case of peri-implantitis and...

A 66-year-old man was referred to our hospital for further treatment of ORN of the mandible. He had undergone dental implant treatments on both sides of the mandible (#35, #36, #45, and #47) 7 years previously. All of the implants were osseointegrated and charged. The patient had been followed up regularly by his dentist, and the clinical course had remained uneventful. He experienced left oropha...

Background : A case of peri-implantitis and osteor...

Osteoradionecrosis (ORN) of the mandible is a severe complication that follows ionizing radiation therapy in patients undergoing treatment for head and neck cancer. The radiation dose, tumor location, dental trauma, premorbid state of dentition, and concomitant chemoradiotherapy are thought to be contributing factors for ORN [1–3]. Most patients with head and neck cancer are aged 50 years or mo...

Abstract : A case of peri-implantitis and osteorad...

A little is known about the effect of radiotherapy on the dental implants that have previously been osseointegrated and charged. Here, we reported a case of osteoradionecrosis which arose around dental implants placed before radiation therapy.

Fig. 8. EDS 5 min : Achieving surface chemical an...

Fig. 8. EDS 5 min Fig. 8. EDS 5 min

Fig. 7. EDS 3 min : Achieving surface chemical an...

Fig. 7. EDS 3 min Fig. 7. EDS 3 min

Fig. 6. EDS 1 min : Achieving surface chemical an...

Fig. 6. EDS 1 min Fig. 6. EDS 1 min

Fig. 5. EDS control : Achieving surface chemical a...

Fig. 5. EDS control Fig. 5. EDS control

Fig. 4. Group 4—5 min : Achieving surface chemi...

Fig. 4. Group 4—5 min Fig. 4. Group 4—5 min

Fig. 3. Group 3—3 min : Achieving surface chemi...

Fig. 3. Group 3—3 min Fig. 3. Group 3—3 min

Fig. 2. Group 2—1 min : Achieving surface chemi...

Fig. 2. Group 2—1 min Fig. 2. Group 2—1 min

Fig. 1. Group control : Achieving surface chemical...

Fig. 1. Group control Fig. 1. Group control

Table 9 Chemical analysis of surface (group 4 spec...

Element Weight % Atoms % Carbon 15.07 26.19 ...

Table 8 Chemical analysis of surface (group 4 spec...

Element Weight % Atoms % Carbon 10.43 23.42 ...

Table 7 Chemical analysis of surface (group 3 spec...

Element Weight % Atoms % Carbon 4.12 15.29 ...

Table 6 Chemical analysis of surface (group 3 spec...

Element Weight % Atoms % Carbon 4.79 18.86 ...

Table 5 Chemical analysis of surface (group 2 spec...

Element Weight % Atoms % Carbon 8.54 31.34 ...

Table 4 Chemical analysis of surface (group 2 spec...

Element Weight % Atoms % Carbon 4.47 19.93 ...

Table 3 Chemical analysis of surface (group 1 spec...

Element Weight % Atoms % Carbon 8.02 38.2 ...

Table 2 Chemical analysis of surface (group 1 spec...

Element Weight % Atoms % Carbon 8.22 37.21 ...

Table 1 Distribution of groups : Achieving surface...

Groups Plasma electrolytic oxidation—time (min) Voltage (V) Current (A) 1 – –   2 1 ΔU = 160 to 200 V ≅0.18 3 3 ΔU = 160 to 280 V ≅0.19 4 5 ΔU = 160 to 300 V ≅0.18   Table 1 Distribution of groups

About this article : Achieving surface chemical an...

Goularte, M.A.P.C., Barbosa, G.F., da Cruz, N.C. et al. Achieving surface chemical and morphologic alterations on tantalum by plasma electrolytic oxidation. Int J Implant Dent 2, 12 (2016). https://doi.org/10.1186/s40729-016-0046-2 Download citation Received: 18 November 2015 Accepted: 12 April 2016 Published: 16 April 2016 DOI: https://doi.org/10.1186/s40729-016-0046-2

Rights and permissions : Achieving surface chemica...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Achieving surface chemica...

The authors declare that they have no competing interests. MAPCG contributed to the concept/design, data collection, data analysis/interpretation, drafting of the article, critical revision of the article, and approval of the article. GFB carried out the data analysis/interpretation, drafting of the article, critical revision of the article, and approval of the article. NCC contributed to the dat...

Author information : Achieving surface chemical an...

Department of Prosthodontics, Implantology Pontifical Catholic University of Rio Grande do Sul - PUCRS, Av. Ipiranga, 6681 Prédio 06, Partenon, CEP: 90619-900, Porto Alegre, RS, Brazil Marcelo Augusto Pinto Cardoso Goularte Clinical Department, Universidade Luterana do Brasil - Torres (ULBRA-TORRES), Rua Universitária, 1900, Parque do Balonismo, CEP 95560-000, Torres, RS, Brazil Gustavo Frain...

References : Achieving surface chemical and morpho...

Yerokhin AL, Nie X, Leyland A, Matthews A, Dowey SJ. Plasma electrolysis for surface engineering. Surf Coat Technol. 1999;122(2-3):73–93. doi:10.1016/S0257-8972(99)00441-7. Hosoki M, Nishigawa K, Miyamoto Y, Ohe G, Matsuka Y. Allergic contact dermatitis caused by titanium screws and dental implants. J Prosthodont Res. 2016. doi: 10.1016/j.jpor.2015.12.004. [Epub ahead of print]. Goutam M, Giri...

References : Achieving surface chemical and morpho...

Gittens RA, Olivares-Navarrete R, Cheng A, Anderson DM, McLachlan T, Stephan I, et al. The roles of titanium surface micro/nanotopography and wettability on the differential response of human osteoblast lineage cells. Acta Biomater. 2013;9(4):6268–77. doi:10.1016/j.actbio.2012.12.002. Epub 2012 Dec 8. Bauer S, Schmuki P, von der Mark K, et al. Engineering biocompatible implant surfaces part I: ...

Discussion and conclusions : Achieving surface che...

Thus, this study has examined the possibility of activating an alteration surface in tantalum using the anodizing process, which is effective in other metals like titanium. From our findings, it was possible to develop time exposure protocols in order to obtain conductive surface alterations similar to those already available from some of the largest manufacturers of oral implants. Scanning electr...

Discussion and conclusions : Achieving surface che...

The search for new biomaterials and biocompatible metals has always been a common objective of human rehabilitation research centers. In implant dentistry, titanium has successfully established itself as the material of choice for dental implants. However, several studies have reported cases of metal allergy caused by titanium-containing materials [15–17] and some immune dysfunctions in certain ...

Results : Achieving surface chemical and morpholog...

Tables 2 and 3 show similar rates among the chemical elements present on the non-treated tantalum surface—group 1 (Fig. 5). In Tables 4 and 5 (group 2), calcium (Ca) is included. The rates for the other chemical elements are similar to the rates in group 1 (Fig. 6). In Tables 6 and 7, group 3 sample shows the basic chemicals present in previous groups and similar rates (Fig. 7). Two chemic...

Results : Achieving surface chemical and morpholog...

The analysis of the images obtained by scanning electron microscopy confirmed the changes on the surface of tantalum strips according to different exposure times. In Fig. 1, we can observe Ta surface with grooves resulting from the machining of the metal with no surface treatment. As the magnitude increases, the image shows the lines pattern with its peculiar characteristics from the manufacturin...

Methods : Achieving surface chemical and morpholog...

Within a 50-mL tank, the electrolytic solution as described above received a voltage variation of 160 V initial tension at zero time and a final tension at the preset end-time for each group of samples. There was a gradual increase in voltage due to the maintenance of a fairly constant current at around 0.15 to 0.25 A. The electrolytic solution was periodically changed to prevent solution satura...

Methods : Achieving surface chemical and morpholog...

We used 60 strip-shaped samples of tantalum with the following dimensions: 7 mm wide, 11 mm long, and 0.01 mm thick (Kurt J. Lesker Company—USA, 99.95 % purity). The samples were washed in distilled water and placed in an ultrasonic tank containing acetone (Ultra Sonic-1440 Plus—Odontobrás, Ribeirão Preto/SP, Brazil) to remove residues. Then, they were divided into four groups: in group ...

Background : Achieving surface chemical and morpho...

In this way and following the successful results already obtained with Titanium, this study aimed to develop an oxidized surface layer on Tantalum samples and, subsequently, analyze the samples’ topography and levels of salt deposition using an electronic microscope.

Background : Achieving surface chemical and morpho...

The use of materials that come into direct contact with human tissues such as the bone requires maximum biological security. These materials remain for a long period of time or even indefinitely in the human body, and no negative reactions, like toxicity or carcinogenic effects, shall be acceptable. For this reason, biocompatibility of new materials has been widely studied, and only after a lot o...

Abstract : Achieving surface chemical and morpholo...

Search for materials that may either replace titanium dental implants or constitute an alternative as a new dental implant material has been widely studied. As well, the search for optimum biocompatible metal surfaces remains crucial. So, the aim of this work is to develop an oxidized surface layer on tantalum using plasma electrolytic oxidation (PEO) similar to those existing on oral implants bee...

Fig. 3. Peri-implant bone level at baseline, 3 mo...

Fig. 3. Peri-implant bone level at baseline, 3 months post-operative, and 6 months post-operative. a Mesial defect depth. b Mesial defect width. c Distal defect depth. d Distal defect width Fig. 3. Peri-implant bone level at baseline, 3 months post-operative, and 6 months post-operative. a Mesial defect depth. b Mesial defect width. c Distal defect depth. d Distal defect width

Fig. 2. Test group (PRF augmentation) : The effect...

Fig. 2. Test group (PRF augmentation) Fig. 2. Test group (PRF augmentation)

Fig. 1. Control group (no PRF augmentation) : The ...

Fig. 1. Control group (no PRF augmentation) Fig. 1. Control group (no PRF augmentation)

Illustration 11. a–d Post-operative healing proc...

Illustration 11. ive (a), 1 week post-operative (b), 1 month post-operative (c), and 3 months post-operative (d) Illustration 11. a–d Post-operative healing process at 3 days post-operative (a), 1 week post-operative (b), 1 month post-operative (c), and 3 months post-operative (d)

Illustration 10. a–d Second measuring, reentry, ...

Illustration 10. a–d Second measuring, reentry, and insertion of a screwed, full ceramic crown Illustration 10. a–d Second measuring, reentry, and insertion of a screwed, full ceramic crown

Illustration 9. a–c Radiographic control a at ti...

Illustration 9. a–c Radiographic control a at time of implant placement (a), 3 months post-operative (b), and 6 months post-operative (c)

Illustration 8. Fixation of the flap with Seralene...

Illustration 8. Fixation of the flap with Seralene® 6.0 Illustration 8. Fixation of the flap with Seralene® 6.0

Illustration 7. Insertion of PRF membranes in a do...

Illustration 7. Insertion of PRF membranes in a double-layered technique for tissue augmentation Illustration 7. Insertion of PRF membranes in a double-layered technique for tissue augmentation

Illustration 6. PRF membrane made by centrifugatin...

Illustration 6. PRF membrane made by centrifugating and pressing the patient’s blood Illustration 6. PRF membrane made by centrifugating and pressing the patient’s blood

Illustration 5. Implant placed with a split-flap t...

Illustration 5. Implant placed with a split-flap technique Illustration 5. Implant placed with a split-flap technique

Illustration 4. NobelSpeedy Replace® (source: htt...

Illustration 4. NobelSpeedy Replace® (source: https://www.nobelbiocare.com/de/de/home/products-and-solutions/implant-systems/nobelspeedy.html) Illustration 4. NobelSpeedy Replace® (source: https://www.nobelbiocare.com/de/de/home/products-and-solutions/implant-systems/nobelspeedy.html)

Illustration 3. Insertion of the implant : The eff...

Illustration 3. Insertion of the implant Illustration 3. Insertion of the implant

Illustration 2. Crestal incision and preparation o...

Illustration 2. Crestal incision and preparation of a split-flap Illustration 2. Crestal incision and preparation of a split-flap

Illustration 1. Measurement of tissue thickness wi...

Illustration 1. Measurement of tissue thickness with an endodontic micro-opener Illustration 1. Measurement of tissue thickness with an endodontic micro-opener

About this article : The effect of PRF (platelet-r...

Hehn, J., Schwenk, T., Striegel, M. et al. The effect of PRF (platelet-rich fibrin) inserted with a split-flap technique on soft tissue thickening and initial marginal bone loss around implants: results of a randomized, controlled clinical trial. Int J Implant Dent 2, 13 (2016). https://doi.org/10.1186/s40729-016-0044-4 Download citation Received: 30 July 2015 Accepted: 23 ...

Rights and permissions : The effect of PRF (platel...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : The effect of PRF (platel...

Julia Hehn, Thomas Schwenk, Marcus Striegel, and Markus Schlee declare that they have no competing interests. This study was self-supported. JH was responsible for the study design and recruitment of the patients, carried out the implant surgery and follow-up examinations, and drafted the manuscript. TS participated in the surgical treatment and follow-up examinations. MS performed the digital me...

Author information : The effect of PRF (platelet-r...

Periodontology, Edel & Weiß Clinic, Ludwigsplatz 1a, 90403, Nuremberg, Germany Julia Hehn Esthetic Dentistry, Edel & Weiß Clinic, Nuremberg, Germany Thomas Schwenk & Markus Striegel Private Clinic for Periodontology, Forchheim and Department of Maxillofacial Surgery, Goethe University, Frankfurt, Germany Markus Schlee You can also search for this author in PubMed...

Acknowledgements : The effect of PRF (platelet-ric...

The authors thank Dr. Wolfgang Reimers of MedCommTools for performing the statistics.

References : The effect of PRF (platelet-rich fibr...

Abrahamsson I, Berglundh T. Effects of different implant surfaces and designs on marginal bone-level alterations: a review. Clin Oral Implants Res. 2009;20 Suppl 4:207–15. Download references

References : The effect of PRF (platelet-rich fibr...

Dohan DM et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part II: platelet-related biologic features. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3):e45–50. Choukroun J, et al. Platelet-rich fibrin (PRF): a second-generation platelet concentrate. Part IV: clinical effects on tissue healing. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101(3)...

References : The effect of PRF (platelet-rich fibr...

Cardaropoli G et al. Tissue alterations at implant-supported single-tooth replacements: a 1-year prospective clinical study. Clin Oral Implants Res. 2006;17(2):165–71. Fickl S et al. Dimensional changes of the alveolar ridge contour after different socket preservation techniques. J Clin Periodontol. 2008;35(10):906–13. Vela-Nebot X et al. Benefits of an implant platform modification techniqu...

Abbreviations : The effect of PRF (platelet-rich f...

platelet-derived growth factor platelet-rich fibrin standard deviation transforming growth factor-b

Conclusions : The effect of PRF (platelet-rich fib...

Soft tissue augmentation with PRF using a split-flap technique cannot be recommended to alter thin gingiva types. Future experimental and clinical studies will be necessary to evaluate whether augmentation with PRF is suitable for mucosa thickening.

Discussion : The effect of PRF (platelet-rich fibr...

With respect to marginal bone loss, it could be shown that there were no significant differences when comparing dimension of bone loss between test and control groups. The study of present research data shows, to the best knowledge of the authors, no other RCTs about tissue thickening with PRF and peri-implant bone loss. However, several studies focused on mucosa thickening with tissue grafts and ...

Discussion : The effect of PRF (platelet-rich fibr...

In this study over a period of 6 months, it could be demonstrated that mucosal tissue thickening above implants with PRF led to reduced tissue thickness when performed in a split-flap technique. The initial post-operative dehiscence and the associated complete loss of mucosal and augmented tissue above the implant were observed in all test patients. PRF is supposed to be a good healing aid in v...

Results : The effect of PRF (platelet-rich fibrin)...

The mean marginal bone level alterations are displayed in Fig. 3. Six months after surgery, both groups showed a statistically significant peri-implant bone loss. The mesial resp. distal defect depth was 0.70 mm ± 0.72 SD resp. 0.64 mm ± 0.66 SD at baseline. Six months later, the marginal bone defect increased to 1.47 mm ± 0.65 SD on the mesial side resp. 1.46 mm ± 0.54 ...

Results : The effect of PRF (platelet-rich fibrin)...

At time of surgery, the patients ranged in age from 33 to 79 years (mean age 53.8 years). The first surgeries for implant placement in the test group were carried out as described above. Two layers of a PRF matrix were placed on top of the implant. Though surgical flaps were all sutured completely free of tension, a post-operative dehiscence above the implant could be observed in all test pati...

Methods : The effect of PRF (platelet-rich fibrin)...

Comparison of bone level alterations between test and control groups. Data were expressed as means ± standard deviation. Comparisons were made using the Wilcoxon test, the Mann–Whitney U test, and the multiple comparisons test by Schaich-Hamerle (p = 0.05).

Methods : The effect of PRF (platelet-rich fibrin)...

After the implantation, standardized digital X-rays were taken with parallel technique (baseline) (illustration 9). For each patient, an individual customized digital film holder was fabricated to ensure a reproducible radiographic analysis. Patients were instructed to avoid chewing hard nutrition in the treated area and to use chlorhexidine mouthwash and a soft brush twice a day for the first 2 ...

Methods : The effect of PRF (platelet-rich fibrin)...

Patients aged 18+ who required an implant in the posterior mandible were eligible for this study. Exclusion criteria were the following: general contraindications to implant surgery insufficient oral hygiene and periodontitis patients with a history of severe periodontitis bone augmentation required smokers substance abuse uncontrolled diabetes severe cardiovascular problems treated or u...

Background : The effect of PRF (platelet-rich fibr...

As a consequence, recent research focused on soft tissue augmentation of thin gingiva types prior to or simultaneous to implant insertion. Wiesner et al. published a significant gain of soft tissue by thickening the gingiva with a connective soft tissue graft harvested from the palate [12]. Soft tissues at augmented sites were 1.3 mm thicker than on control sites and had a better pink esthetic sc...

Background : The effect of PRF (platelet-rich fibr...

The initial bone modeling around implants within the first year after insertion presents a challenging topic in current research. Previous studies have shown that this process is characterized by a remodeling of the horizontal and vertical bone dimension with a range of 0.7 to 3 mm within the first year [1]. First attempts to reduce this loss of tissue focused on changes of implant shapes, impla...

Abstract : The effect of PRF (platelet-rich fibrin...

Previous studies have shown that adequate thickness or initial augmentation of soft tissue has a positive effect on the stability of peri-implant bone. This randomized, controlled trial aimed to evaluate the influence of augmenting soft tissue with platelet-rich fibrin (PRF) on crestal bone and soft tissue around implants. After randomization, 31 fully threaded titanium implants were inserted in ...

Fig. 3. Site of evaluation. (1) Corner of the mout...

Fig. 3. Site of evaluation. (1) Corner of the mouth: 5 mm below the corner of the mouth. (2) Lower lip: 5 mm laterally from the midline. (3) Mental region: at the midpoint of the perpendicular from the lower edge to the lower lip to the chin and 5 mm laterally from the midline Fig. 3. Site of evaluation. (1) Corner of the mouth: 5 mm below the corner of the mouth. (2) Lower lip: 5 mm lat...

Fig. 2. a SW perception tester is composed of diff...

Fig. 2. started from a filament of 0.165 mm in diameter of the most weak force, and performed three times at one site Fig. 2. a SW perception tester is composed of different diameters (a: 0.165 mm, b: 0.215 mm, c: 0.315 mm). b The use of SW perception tester started from a filament of 0.165 mm in diameter of the most weak force, and performed three times at one site

Fig. 1. Alveolar nerve repositioning in a partiall...

Fig. 1. Alveolar nerve repositioning in a partially edentulous mandible. a Preoperative radiograph. b The inferior alveolar nerve was transposed from the mental foramen. c Postoperative radiograph after implant insertion Fig. 1. Alveolar nerve repositioning in a partially edentulous mandible. a Preoperative radiograph. b The inferior alveolar nerve was transposed from the mental foramen. c Po...

Table 2 Results of assessment of sensory neural fu...

No. Sex Age (years) Range of IAN lateralization (width) Implant site Follow-up period (months) ...

Table 1 Highet grading : Subjective and qualitativ...

Stage 0 Complete sensory loss Stage 1 Advent of deep pain Stage 2 Some degree of tactile recovery and pain ...

About this article : Subjective and qualitative as...

Nishimaki, F., Kurita, H., Tozawa, S. et al. Subjective and qualitative assessment of neural disturbance after inferior alveolar nerve transposition for dental implant placement. Int J Implant Dent 2, 14 (2016). https://doi.org/10.1186/s40729-016-0047-1 Download citation Received: 25 July 2015 Accepted: 26 April 2016 Published: 14 May 2016 DOI: https://doi.org/10.1186/s40...

Rights and permissions : Subjective and qualitativ...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : Subjective and qualitativ...

Fumihiro Nishimaki, Hiroshi Kurita, Shinya Tozawa, Yuji Teramoto, Rishiho Nishizawa, and Shin-ichi Yamada declare that they have no competing interests. FN and HK conceived and designed the study, performed the experiments, and wrote the manuscript. ST and YT performed data analysis. RN and SY participated in manuscript preparation. All authors read and approved the final version of the manuscrip...

Author information : Subjective and qualitative as...

Department of Dentistry and Oral Surgery, Shinshu University School of Medicine, 3-3-1, Asahi, Matsumoto-shi, Nagano, 390-0804, Japan Fumihiro Nishimaki, Hiroshi Kurita, Shinya Tozawa, Yuji Teramoto, Rishiho Nishizawa & Shin-ichi Yamada You can also search for this author in PubMed Google Scholar You can also search for this author in Pub...

Acknowledgements : Subjective and qualitative asse...

All authors have reviewed the article and agreed to the submission.

References : Subjective and qualitative assessment...

Morrison A, Chiaro M, Kirby S. Mental nerve function after inferior alveolar nerve transposition for placement of dental implants. J Can Dent Assoc. 2002;62:46–50. Vetromilla BM, Moura LB, Sonegi CL, et al. Complications associated with inferior alveolar nerve repositioning for dental implant placement: a systematic review. Int J Oral Maxillofac Surg. 2014;43(11):1360–6. Eggers G, Klein J, e...

References : Subjective and qualitative assessment...

Levin L, Sadet P, Grossmann Y. A retrospective evaluation of 1387 single-tooth implants: a six-year follow-up. J Periodontol. 2006;77:2080–3. Levin L. Dealing with dental implant failures. J Appl Oral Sci. 2008;16:171–5. Lorean A, Kablan F, Mazor Z, et al. Inferior alveolar nerve transposition and reposition for dental implant placement in edentulous or partially edentulous mandibles: a mult...

Conclusions : Subjective and qualitative assessmen...

In conclusion, we investigated the quality of postoperative neurosensory function after IAN transposition for dental implant placement. IAN transposition is a useful method for placing implants in the atrophic posterior mandible. However, the procedure is complicated, with the possibility of some degree of neurosensory disturbance, although in most of our cases, it resolved within a clinically acc...

Discussion : Subjective and qualitative assessment...

Dental restoration by means of dental implants can provide good functional rehabilitation, particularly in patients with atrophic mandibles. IAN lateralization is a useful method for placing implants in the atrophic posterior mandible. However, there is a possibility of the neurosensory function of the IAN being disturbed, although in most cases, it resolves within a clinically acceptable period. ...

Discussion : Subjective and qualitative assessment...

Although the previous studies reported good results concerning ND in IAN transposition surgery, the methods for evaluating ND differed, and most of the studies did not fully describe the evaluation procedure. The evaluation of ND of the IAN can be performed by purely subjective (questionnaire), relatively objective (static light touch, 2-point discrimination, etc.), and purely objective methods (t...

Discussion : Subjective and qualitative assessment...

IAN reposition may serve as a viable treatment option in the severely resorbed mandibles. Repositioning is performed via one of the two surgical techniques, lateralization, or transposition, with lateralization yielding lower degrees of nerve deficiency. In lateralization, the IAN is exposed and retracted laterally, held in this position during implant placement, then released to rest against the ...

Results : Subjective and qualitative assessment of...

In total, eight IAN transposition procedures were performed in seven patients. One patient underwent bilateral surgery. Surgery was performed under general anesthesia in four patients and under local anesthesia in three patients. The IAN was lateralized for a four-tooth breadth on one side, three-tooth breadth on three sides, and two-tooth breadth on three sides. In total, 22 dental implants were ...

Methods : Subjective and qualitative assessment of...

This study was conducted in compliance with the principles of the Declaration of Helsinki, and was approved by the Committee for Ethics at Shinshu University School of Medicine. Patients who underwent dental rehabilitation by insertion of dental implants between 2000 and 2012 in our hospital were reviewed. Of these, seven patients underwent transposition of the IAN for dental implant placement and...

Background : Subjective and qualitative assessment...

Tooth loss is one of the common causes of reduced quality of life in adults. Dental implants have become a widely accepted treatment option for both partially and completely edentulous patients [1–3]. However, in cases of posterior mandibular atrophy, suitably sized implants cannot be placed without encroaching on the inferior alveolar nerve (IAN). In such cases, restorative options include the ...

Abstract : Subjective and qualitative assessment o...

The purpose of this retrospective study was to accumulate data regarding the quality of postoperative neurosensory function after inferior alveolar nerve (IAN) transposition for dental implant placement. The study included seven consecutive patients who underwent IAN transposition surgery for the insertion of a dental implant into the atrophic posterior mandible. Of these, six patients (seven sid...

Fig. 9. Comparison of the CBD medians in the immed...

Fig. 9. Comparison of the CBD medians in the immediate implant and the control groups Fig. 9. Comparison of the CBD medians in the immediate implant and the control groups

Fig. 8. Comparison of the CBD means in the immedia...

Fig. 8. Comparison of the CBD means in the immediate implant and the control groups Fig. 8. Comparison of the CBD means in the immediate implant and the control groups

Fig. 7. CBD in millimeters plotted over 10 years ...

Fig. 7. CBD in millimeters plotted over 10 years for the control group Fig. 7. CBD in millimeters plotted over 10 years for the control group

Fig. 6. CBD in millimeters plotted over 10 years ...

Fig. 6. CBD in millimeters plotted over 10 years for the immediate implant group Fig. 6. CBD in millimeters plotted over 10 years for the immediate implant group

Fig. 5. Measurement specifications: clinical reali...

Fig. 5. Measurement specifications: clinical realization [6] Fig. 5. Measurement specifications: clinical realization [6]

Fig. 4. Measurement specifications: outline [6] : ...

Fig. 4. Measurement specifications: outline [6] Fig. 4. Measurement specifications: outline [6]

Fig. 3. Number of implants in the respective regio...

Fig. 3. Number of implants in the respective region (anterior region ranging from 13 to 23 and 33 to 43, and posterior region ranging from 18 to 14, 24 to 28, 38 to 34, and 44 to 48) Fig. 3. Number of implants in the respective region (anterior region ranging from 13 to 23 and 33 to 43, and posterior region ranging from 18 to 14, 24 to 28, 38 to 34, and 44 to 48)

Fig. 2. Prosthodontic indications : Peri-implant

Fig. 2. Prosthodontic indications Fig. 2. Prosthodontic indications

Fig. 1. On the left, the Tübingen ceramic implant...

Fig. 1. On the left, the Tübingen ceramic implant; on the right, the Frialit stepped-screw implant. The transgingival part with the cervical groove of the Tübingen implant has been removed in the Frialit implant; this part is now replaced by a mirror-polished transgingival portion of the Frialit abutment; all the intraosseous portion of the implant has now a thread and is shaped like the origi...

Table 4 Analysis of the statistical tests : Peri-i...

IM vs. CG Insertion Prosthetic treatment 1st year after prosthetic treatment 2nd year after prosthetic treatment ...

Table 3 Formula for the CBD : Peri-implant bone ch...

Implant diameter and length Formula for the calculation of the CBD (CBD = coronal bone defect) (DD = defect depth) 3.8 × 13 mm CBD = DD + 5 mm 3.8 × 15 mm CBD = DD + 7 mm All other diameters CBD = DD + 3.2 mm   Table 3 Formula for the CBD

Table 2 Number and dimension of the implants : Per...

  Length (mm) Diameter 10 13 15 3.8 mm 0 ...

Table 1 Distribution of implants according to the ...

  Age (year) Gender 15–20 21–40 41–60 61–75 Fe...

About this article : Peri-implant bone changes in ...

Gomez-Roman, G., Launer, S. Peri-implant bone changes in immediate and non-immediate root-analog stepped implants—a matched comparative prospective study up to 10 years. Int J Implant Dent 2, 15 (2016). https://doi.org/10.1186/s40729-016-0048-0 Download citation Received: 03 November 2015 Accepted: 14 May 2016 Published: 23 May 2016 DOI: https://doi.org/10.1186/s40729-...

Rights and permissions : Peri-implant bone changes...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Peri-implant bone changes in ...

Department of Prosthodontics, Dental School, University of Tübingen, Osianderstr. 2-8, Tübingen, D-72076, Germanyᅟ German Gomez-Roman & Steffen Launer You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar Correspondence to German Gomez-Roman.

Acknowledgements : Peri-implant bone changes in im...

The study was supported by the German Society of Research, Special research project 175, Implantology (DFG—Deutsche Forschungsgemeinschaft, Sonderforschungsbereich 175, Implantologie). The authors of this study express their appreciation to Dr. Detlef Axmann for the expert advice in statistics. GG-R conceived of the study and participated in its design and coordination and helped to draft the m...

References : Peri-implant bone changes in immediat...

Perry J, Lenchewski E. Clinical performance and 5-year retrospective evaluation of Frialit-2 implants. Int J Oral Maxillofac Implants. 2003;19(6):887–91. Quirynen M, Van Assche N, Botticelli D, Berglundh T. How does the timing of implant placement to extraction affect outcome? Int J Oral Maxillofac Implants. 2007;22:203–26. Ortega-Martínez J, Pérez-Pascual T, Mareque-Bueno S, Hernández-Al...

References : Peri-implant bone changes in immediat...

Lsidor F. Clinical probing and radiographic assessment in relation to the histologic bone level at oral implants in monkeys. Clin Oral Implants Res. 1997;8(4):255–64. doi:10.1034/j.1600-0501.1997.080402.x. Zechner W, Watzak G, Gahleitner A, Busenlechner D, Tepper G, Watzek G. Rotational panoramic versus intraoral rectangular radiographs for evaluation of peri-implant bone loss in the anterior a...

References : Peri-implant bone changes in immediat...

Brånemark P-I. Osseointegration and its experimental background. J Prosthet Dent. 1983;50(3):399–410. Schulte W, Heimke G. Das Tübinger Sofortimplantat. Quintessenz. 1976;27(6):17–23. Cooper LF, Raes F, Reside G, Garriga JS, Tarrida LG, Wiltfang J, et al. Immediate provisionalization of dental implants placed in healed alvelar ridges and extraction sockets: a 5-year prospective evaluation....

Abbreviations : Peri-implant bone changes in immed...

coronal bone defect (part of the implant that has no contact to the bone; a calculated value) control group defect depth visible in the radiographs dots per inch immediate implant group interquartile range

Conclusions : Peri-implant bone changes in immedia...

The examination and comparison of the peri-implant bone situation in immediate implants and a control group of non-immediate implants that were matched following specific criteria over a long period of time (10 years) has shown statistically significant differences only at the time of insertion and for the Wilcoxon hypothesis in the second year after prosthetic treatment. In our study, immediate ...

Discussion : Peri-implant bone changes in immediat...

When Quirynen et al. did their review on how the time difference between extraction or tooth loss and implantation affects the success of the implant, no significant difference could be found [27]. They as well as Ortega-Martínez et al. clearly demand more studies evaluating the bone situation for the future [28]. This question was the motivation for our study.

Discussion : Peri-implant bone changes in immediat...

Studies that evaluate the peri-implant bone situation specifically in the Frialit 2 implant system were, among others, conducted by Krennmair et al. and Ricci et al. Krennmair et al. found a bone resorption of 1.4 ± 1.2 mm over their follow-up period [24], which compares to the results found in this study. Ricci et al. found a higher bone resorption of the crestal bone after a 5-year follow-...

Discussion : Peri-implant bone changes in immediat...

The fact that the used measurement protocol is reliable has been proven in former studies [7, 8]. The use of intraoral radiographs as well as panoramic radiographs is an accepted method for the peri-implant bone evaluation [11–13]. The radiographic distortions present in panoramic imaging are well known; however, according to several studies, panoramic images are suitable to assess the crestal ...

Discussion : Peri-implant bone changes in immediat...

The primary objective of this study was the assessment of the peri-implant bone situation in immediate implants over a long-term period up to 10 years and to compare it to the situation found in matched non-immediate implants because there are no similar studies published. The hypothesis was that both the immediate implantation and the implantation after a healing period using the Frialit 2 impla...

Results : Peri-implant bone changes in immediate a...

Comparing the medians (Fig. 9) of the IM and CG, a difference of 0.7 mm at the time of insertion is visible. The respective values were 0 mm for the CG and 0.7 mm for the IM group. While at the time the patients received their definite restorations, a difference of only 0.3 mm was recorded (0.9 mm for IM and 0.6 mm for CG). Over the years after definite restorations were emplaced, the medi...

Results : Peri-implant bone changes in immediate a...

The corresponding group of non-immediate implants was named the control group (CG) and analyzed the same way, and the results are shown in Fig. 7. Like the immediate implant group, the mean values for the CG mainly stayed stable. At the time of insertion, a value of 0.6 mm was found, which was a little smaller than the value found at the time of the prosthetic treatment (1.0 mm). The maximum v...

Results : Peri-implant bone changes in immediate a...

For the evaluation of the received data, immediate and non-immediate implants were first examined separately. The immediate implant (IM) group and its CBD plotted against the time, starting at the time of insertion, is shown in Fig. 6. One can see that the data are quite homogeneous. The arithmetic means of the CBD range from 1.0 to 1.9 mm, most of them lying between 1.1 and 1.5 mm. The lowes...

Methods : Peri-implant bone changes in immediate a...

After this, the data set was imported into the Excel program (Microsoft Corporation, Redmond, WA 980526399, USA) for further breakdown. For the final examination of the observed values, the mesial and distal CBD was compared. Since there were no larger differences of the values, the mesial and distal CBD were averaged and this was used for further assessment. The gained results were visualized usi...

Methods : Peri-implant bone changes in immediate a...

The protocol used for measuring the distances in every radiograph was described by the author [6] and is outlined in Figs. 4 and 5. Crucial is the determination of a reliable reference line for every implant type. Rather than measuring only the bone level, the “coronal bone defect,” described by the author in 1995 [6], is assessed, which is the extent to which the part of the implant that is ...

Methods : Peri-implant bone changes in immediate a...

One hundred and thirty-three patients receiving 174 implants were selected: 87 immediate implants (IM) and as a matched group 87 implants that were inserted in healed bone (control group (CG)). The mean age of the patients in this study was 42 years, the youngest patient being 15 years old and the oldest 75 years at the time they received their implant. A gender and age distribution of all ins...

Methods : Peri-implant bone changes in immediate a...

All patients within this study were treated at the Dental School of the Eberhard Karls University in Tübingen between the 22nd of February in 1991 and the 24th of October in 2005. Every patient received at least one Frialit implant. The study protocol of the study was approved by the German Society of Research (Sonderforschungsbereich 175 Implantologie). Informed consent was obtained from all pat...

Background : Peri-implant bone changes in immediat...

The present study was designed as a retrospective long-term study which compares the peri-implant bone situation of immediate implants and non-immediate implants as a control group (matched with specific criteria) using reliable measurement specifications [6–8]. The hypothesis was that both the immediate implantation and the implantation after a healing period using the Frialit 2 implant system ...

Background : Peri-implant bone changes in immediat...

The success of dental implants has become more and more predictable since Brånemark first observed what he later called osseointegration, in 1960 [1], meaning the direct structural and functional interlocking of the natural bone and titanium implant surfaces. With implantation becoming a predictable treatment for dental restorations, patients also have become more critical towards the esthetic ou...

Abstract : Peri-implant bone changes in immediate ...

The purpose of this retrospective long-term study was to evaluate the peri-implant bone changes in immediate implants and matched non-immediate implants as a control group using a specific and proven measurement protocol over a 10-year period, because there are no similar studies published. One hundred and thirty-three patients received 174 implants (immediate implants (IM) n = 87; control gr...

Table 4 The correlation between personal traits an...

   Neuroticism Extraversion Openness Agreeableness Conscientiousness SBP_ER (%) ...

Table 3 NEO-FFI score of the patients. This questi...

  NEO-FFI score No. Neuroticism Extraversion Openness Agreeableness ...

Table 2 Elevation rate (ER) of each index. Blood p...

  Elevation rate No. SBP (%) DBP (%) MDP (%) PR (%) RPP (%) 1 36.3 25.0 30.3 2.9 40 2 12.9 14.0 13.5 7.3 21 3 16.4 24.6 20.8 54.3 80 4 1.4 0.0 0.6 20.0 22 5 10.0 23.8 17.6 −3.1 7 6 33.0 28.6 30.4 8.3 44 7 48.6 13.8 27.5 0.0 49 8 −10.8 −17.8 −14.8 −9.0 −19 9 33.8 33.0 33.3 2.4 ...

Table 1 Overview of the patients’ data. All inde...

No. Sex Age SBP (mmHg) DBP (mmHg) MDP (mmHg) PR (bpm) ...

About this article : A prospective study of the re...

Wada, M., Miwa, S., Mameno, T. et al. A prospective study of the relationship between patient character and blood pressure in dental implant surgery. Int J Implant Dent 2, 21 (2016). https://doi.org/10.1186/s40729-016-0054-2 Download citation Received: 14 May 2016 Accepted: 20 October 2016 Published: 02 November 2016 DOI: https://doi.org/10.1186/s40729-016-0054-2

Rights and permissions : A prospective study of th...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : A prospective study of the re...

Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan Masahiro Wada, Syunta Miwa, Tomoaki Mameno, Tohru Suganami, Kazunori Ikebe & Yoshinobu Maeda You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also...

References : A prospective study of the relationsh...

Guasti L, Diolisi A, Gaudio G, Grimoldi P, Petrozzino R, Uslenghi S, Bertolini A, Grandi AM, Venco A. Reactivity of blood pressure to mental arithmetic stress test, stress-test recovery time, and ambulatory blood pressure in hypertensive and normotensive subjects. Blood Press Monit. 1998;3(5):275–80. Eli I, Schwartz-Arad D, Baht R, Ben-Tuvim H. Effect of anxiety on the experience of pain in imp...

References : A prospective study of the relationsh...

Peleg M, Sawatari Y, Marx RN, Santoro J, Cohen J, Bejarano P, Malinin T. Use of corticocancellous allogeneic bone blocks for augmentation of alveolar bone defects. Int J Oral Maxillofac Implants. 2010;25(1):153–62. Cairo F, Pagliaro U, Nieri M. Soft tissue management at implant sites. J Clin Periodontol. 2008;35(8 Suppl):163–7. Coulthard P. Should GDPs be checking blood pressure? Br Dent J. ...

Conclusions : A prospective study of the relations...

In this limited study, there was a significant correlation between neuroticism character and diastolic blood pressure or mean blood pressure rising in patients who received implant surgery.

Discussion : A prospective study of the relationsh...

On the other hand, there was no correlation between SBP and neuroticism character. For this reason, it is thought that the range of SBP is usually wide compared to DBP. However, there are some reports about the correlation between SBP and patients’ personality trait [20]. Besides, the excessive rise in SBP during the operation may adversely affect the condition of the patients. Therefore, a furt...

Discussion : A prospective study of the relationsh...

The blood pressure is considered to be affected by many factors, including physical and psychological stress in dental treatment. From a physical aspect, there are many reports about the relationship between blood pressure and local anesthesia or pain [8–11]. In fact, Tsuchihashi et al. reported that there was a correlation between increased blood pressure and infiltrated anesthesia amount [12]...

Results : A prospective study of the relationship ...

Ten females and five males (mean 55.5 ± 10.6 years) were evaluated in this study (Table 1). Tables 2 and 3 show the patients’ blood pressure, pulse rate, and NEO-FFI scores. Average values of blood pressure and pulse rate at the first visit were 121.2 mmHg; SBP, 74.9 mmHg; DBP, 90.4 mmHg; MBP, 81.6 bpm; PR, RPP, 9791 bpm × mmHg and 143.0 mmHg; SBP, 87.1 mmHg; DBP, 105.7 mmHg...

Methods : A prospective study of the relationship ...

Fifteen patients were recruited for the present study. All the patients had never received implant treatment in the past. The patients were not accepted into this study if they met any of the following exclusion criteria: (1) experience of implant treatment in the past, (2) general contraindications to implant surgery, (3) moderate or severe hypertension or cardiovascular system disease, and (4) m...

Background : A prospective study of the relationsh...

Implant prosthesis has already become one of the treatment options for missing teeth. In addition, under the appropriate maintenance therapy, its longevity is equal or higher compared to the other prosthetic treatments. On the other hand, patients who want to receive the implant treatment cannot avoid the insertion surgery. In addition, if there are hard or soft tissue defects at the planned site,...

Abstract : A prospective study of the relationship...

Patients often suffer from physical and mental stress in dental implant surgery. The aim of this prospective study is to investigate the relationship between patient character and blood pressure in dental implant surgery. Fifteen patients were recruited for the present study. All patients had never received implant treatment in the past. To evaluate the patients’ personality trait, NEO-Five Fac...

Table 2 Clinical studies included : To what extent...

  Patients Intervention Follow-up Outcome Study Reference No. Agea No. of implants Position Supra-structure   Change Declarations (DAVIS et al. 1999) [17] 44 61.2 NG Symphyseal Fixed 6.6 Ya VBH (−.8 to +3.3 mm) – R (Powers et al. 1994) [32] 146 52 NG TMI Fixed 18–51 M BF (+2 to 9 mm) – R (Adell et al. 1981) [58] 410 53 276...

Table 1 Systematic search strategy : To what exten...

Focus question In patient with implant restoration, what is the chance of residual alveolar ridge preserving and bone formation in the adaptive remodeling and what are the features of this preservation? Search strategy  Population #1—edentulous patient  Intervention #2—implant OR overdenture OR fixed bridge OR transmandibular implant OR full rehabilitation  O...

About this article : To what extent residual alveo...

Khalifa, A.K., Wada, M., Ikebe, K. et al. To what extent residual alveolar ridge can be preserved by implant? A systematic review. Int J Implant Dent 2, 22 (2016). https://doi.org/10.1186/s40729-016-0057-z Download citation Received: 21 May 2016 Accepted: 16 November 2016 Published: 23 November 2016 DOI: https://doi.org/10.1186/s40729-016-0057-z

Rights and permissions : To what extent residual a...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : To what extent residual alveo...

Department of Prosthodontics, Faculty of Dentistry, Mansoura University, 68 ElGomhoria Street, ElMansoura, 35516, Egypt Ahmed Khalifa Khalifa Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan Ahmed Khalifa Khalifa, Masahiro Wada, Kazunori Ikebe & Yoshinobu Maeda You can also searc...

References : To what extent residual alveolar ridg...

Murphy WM, Williams KR, Gregory MC. Stress in bone adjacent to dental implants. J Oral Rehabil. 1995;22(12):897–903. Chou HY, Jagodnik JJ, Müftü S. Predictions of bone remodeling around dental implant systems. J Biomech. 2008;41(6):1365–73. Chang S-H, Huang S-R, Huang S-F, Lin C-L. Mechanical response comparison in an implant overdenture retained by ball attachments on conventional regular...

References : To what extent residual alveolar ridg...

Kremer U, Schindler S, Enkling N, Worni A, Katsoulis J, Mericske-Stern R. Bone resorption in different parts of the mandible in patients restored with an implant overdenture. A retrospective radiographic analysis. Clin Oral Implants Res. 2016;27(3):267-72. von Wowern N, Gotfredsen K. Implant-supported overdentures, a prevention of bone loss in edentulous mandibles? A 5-year follow-up study. Clin ...

References : To what extent residual alveolar ridg...

de Jong MHM, Wright PS, Meijer HJA, Tymstra N. Posterior mandibular residual ridge resorption in patients with overdentures supported by two or four endosseous implants in a 10-year prospective comparative study. Int J Oral Maxillofac Implants. 2010;25(6):1168–74. Jacobs R, Schotte A, van Steenberghe D, Quirynen M, Naert I. Posterior jaw bone resorption in osseointegrated implant-supported over...

References : To what extent residual alveolar ridg...

Block MS, Kent JN, Finger IM. Use of the integral implant for overdenture stabilization. Int J Oral Maxillofac Implants. 1990;5(2):140–7. Norton MR, Gamble C. Bone classification: an objective scale of bone density using the computerized tomography scan. Clin Oral Implants Res. 2001;12(1):79–84. de Oliveira RCG, Leles CR, Normanha LM, Lindh C, Ribeiro-Rotta RF. Assessments of trabecular bone...

References : To what extent residual alveolar ridg...

Cowin SC. Bone stress adaptation models. J Biomech Eng. 1993;115(4B):528. Byrne G. Fundamentals of implant dentistry. New Jersey: Wiley; 2014. 264 p. Traini T, Degidi M, Iezzi G, Artese L, Piattelli A. Comparative evaluation of the peri-implant bone tissue mineral density around unloaded titanium dental implants. J Dent. 2007;35(1):84–92. Hoshaw SJ, Brunski JB, Cochran GVB. Mechanical loading...

References : To what extent residual alveolar ridg...

Roberts WE, Helm FR, Marshall KJ, Gongloff RK. Rigid endosseous implants for orthodontic and orthopedic anchorage. Angle Orthod. 1989;59(4):247–56. Roberts WE, Smith RK, Zilberman Y, Mozsary PG, Smith RS. Osseous adaptation to continuous loading of rigid endosseous implants. Am J Orthod. 1984;86(2):95–111. Wyatt CCLL. The effect of prosthodontic treatment on alveolar bone loss: a review of t...

References : To what extent residual alveolar ridg...

Klemetti E, Kolmakow S. Morphology of the mandibular cortex on panoramic radiographs as an indicator of bone quality. Dentomaxillofacial Radiol. 1997;26(1):22–5. Ortman LF, McHenry K, Hausmann E. Relationship between alveolar bone measured by 125I absorptiometry with analysis of standardized radiographs: 2. Bjorn technique. J Periodontol. 1982;53(5):311–4. Davis WH, Lam PS, Marshall MW, Dorc...

References : To what extent residual alveolar ridg...

Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C. The global burden of oral diseases and risks to oral health. Bull World Health Organ. 2005;83(9):661–9. Nowjack-Raymer RE, Sheiham A. Association of edentulism and diet and Nutrition in US adults. J Dent Res. 2003;82(2):123–6. Araújo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in ...

Conclusions : To what extent residual alveolar rid...

Within the limitation of this review and based on previous studies, implant restoration has a noticeable residual alveolar ridge preservation which varies from reducing rate of physiologic resorption to bone apposition. However, the extension of this preservation from the implant to surrounding bony area, horizontally and vertically, is unknown. So, further studies are needed to elaborate the exte...

Review : To what extent residual alveolar ridge ca...

As most of the previous studies declared the favorable bone preservation of the residual alveolar ridge anteriorly around implants, biomechanically, and according to finite element analysis, bone modifying shows variations depending on the cancellous or cortical nature. Bone density is enhanced gradually from the third month to the end of the first year of loading coming stable after 30 months. W...

Review : To what extent residual alveolar ridge ca...

Despite age-related [71], local and/or systemic factors causing prolonged ridge resorption [9], authors reported the probability of preservative effect and overhaul to maintain the residual alveolar ridge with different restoration [70, 71]. In the previous study, bone formation was noticed with the distal implant in severely resorbed atrophied mandibular ridge [20]. Sennerby et al. [72] concluded...

Review : To what extent residual alveolar ridge ca...

Many procedures are used to recover denture foundation, but the majority is considered sophisticated techniques [51–53]. Observations tried to notify bone modifications with different types of implant-assisted restoration [23, 40, 54]. The clinical and radiographic investigations, detection of the altered mineral levels, or bone density within the bone may give a valuable data for the bony state...

Review : To what extent residual alveolar ridge ca...

Bone changes were reported after implant placement in three phases: healing, remodeling, and equilibrium. The remodeling phase is launched confronting the altered pattern of force transmission to the bone tissue. To withstand the applied functional load, continuous remodeling is conducted to reach a “steady state.” Mechanical stimulus is the primary bone modifier influenced by other in situ va...

Review : To what extent residual alveolar ridge ca...

Apparently, there is an enduring adaptive process surrounding the implant which sustains the rigid interface between alveolar bone and implant after non-destructive surgical and loading procedures. Like other body bones, and according to Wolff’s law, bone has the ability to differentiate with different stresses applied [22]. This reform is started from the time of surgical conduction of implant ...

Review : To what extent residual alveolar ridge ca...

The required documents were collected from PubMed, Web of Science, and Ovid databases. For expanding the traces of researching, further readings for the bibliography of the relevant publications and hand searching for some denoted articles were done. The keywords, for intervention and outcome, used in research engines in databases as “implant overdenture,” “implant bone resorption,” “alv...

Review : To what extent residual alveolar ridge ca...

Edentulism is rated between 7 and 69% internationally [1]. Many biological and non-bilogical predisposing factors lead to the main result of edentulism [2]. Regardless the debate to understand the way of resorption [3], the loss of periodontal ligament by tooth extraction leaves alveolar bone without a chance of reformation which leads to bone resorption only. The resorption shows variation in rat...

Abstract : To what extent residual alveolar ridge ...

It has been reported that the load for (or to) implant-supported restoration may lead to bone remodeling as bone resorption and/or formation. While many authors supported the process of bone resorption, others elaborated bone apposition and increasing bone density close and remote to implant body (or fixture). This may suggest the role of the implant to reserve alveolar ridge from physiologic/path...

Fig. 6. Immunohistochemical staining of osteocalci...

Fig. 6. Immunohistochemical staining of osteocalcin (a) and collagen I (c) in sections from mini pigs mandible from 9M and IR osteocalcin (b) and collagen I (d). There were statistically significant differences to osteocalcin in 9M samples and no statistically significant differences to collagen I samples. Magnification: ×40 (a, b) and ×100 (c, d) Fig. 6. Immunohistochemical staining of ost...

Fig. 5. Representative photomicrographs of each th...

Fig. 5. Representative photomicrographs of each third of the peri-implant bone of IR experimental condition (H&E, ×40). a First third (cervical third). b Intermediate third. c Apical third. Note the edges of bone grooving present rounded contour, mainly in the last third Fig. 5. Representative photomicrographs of each third of the peri-implant bone of IR experimental condition (H&E, ×40). a...

Fig. 4. Representative photomicrographs of each th...

Fig. 4. Representative photomicrographs of each third of the peri-implant bone of 9M experimental condition (H&E, ×40). a First third (cervical third). b Intermediate third. c Apical third. Bone grooving with no altered contour Fig. 4. Representative photomicrographs of each third of the peri-implant bone of 9M experimental condition (H&E, ×40). a First third (cervical third). b Intermediat...

Fig. 3. Prothesis fixed installed on the three imp...

Fig. 3. Prothesis fixed installed on the three implants Fig. 3. Prothesis fixed installed on the three implants

Table 4 Data showing the expression of collagen I ...

  9M IR Third Mean Standard deviation Mean ...

Table 3 Data showing the expression of osteocalcin...

  9M IR Third Mean Standard deviation Mean ...

Table 2 Removal torque value (Ncm) of three implan...

Animal Mean Standard deviation Minimum Maximum 1 150.1 30.2 122.7 184.4 2 163.3 35.1 132.4 205.3 3 175.2 15.2 153.2 204.6 4 163.6 15.4 157.3 185.1 5 153.3 15.2 146.2 174.2 6 150.3 26.4 129.2 174.6   Table 2 Removal torque value (Ncm) of three implants removed after 9 months (9M) per animal

Table 1 Removal torque value (Ncm) of three implan...

Animal Mean Standard deviation Minimum Maximum 1 98.3 5.5 92.2 103.3 2 91.6 9.1 82.1 102.5 3 105.3 8.3 100.4 115.0 4 71.6 10.5 61.2 82.2 5 78.6 5.8 72.7 83.1 6 88.6 6.6 81 93.6   Table 1 Removal torque value (Ncm) of three implants immediate removed (IR) per animal

About this article : Twist removal of healed vs. n...

Silva, R.d., Passador, F. & Caria, P.H.F. Twist removal of healed vs. nonhealed implants—a mechanical and histological study in mini pigs. Int J Implant Dent 2, 23 (2016). https://doi.org/10.1186/s40729-016-0059-x Download citation Received: 27 April 2016 Accepted: 18 November 2016 Published: 25 November 2016 DOI: https://doi.org/10.1186/s40729-016-0059-x

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Twist removal of healed vs. n...

FOP/UNICAMP, Piracicaba, SP, Brasil Ricardo de Oliveira Silva & Paulo Henrique Ferreira Caria CPG São Leopoldo Mandic, Campinas, SP, Brasil Fabrício Passador You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar Correspondence to Ricardo de Oliveira Silva.

Acknowledgements : Twist removal of healed vs. non...

We would like to thank Mario Perussi for supplying us with the customized system, implants, and prosthetic components, Dentifix®, FESB, veterinary professors Rafael Rodrigues and Alexander Correa Borghesan, and CAPES for the scholarship and financial support. ROS conceived the study, held surgical procedures, and drafted the manuscript. FP did the preparation and helped in reading the histologic...

References : Twist removal of healed vs. nonhealed...

Yun H-M, Ahn S-J, Park K-R, Kim M-J, Kim J-J, Jin G-Z, et al. Magnetic nanocomposite scaffolds combined with static magnetic field in the stimulation of osteoblastic differentiation and bone formation. Biomaterials [Internet]. 2016;85:88–98. [cited 2016 Feb 10] Available from: http://www.sciencedirect.com/science/article/pii/S0142961216000491. Download references

References : Twist removal of healed vs. nonhealed...

Aubin JE, Liu F, Malaval L, Gupta AK. Osteoblast and chondroblast differentiation. Bone [Internet]. 1995;17(2):S77–83. [cited 2015 Dec 30] Available from: http://www.sciencedirect.com/science/article/pii/875632829500183E. Mariano M. Minisuíno (minipig) na pesquisa biomédica experimental. O Minipig br1. Acta Cirúrgica Bras. 2003;18(5):387–91. Herring SW. How can animal models answer clinic...

References : Twist removal of healed vs. nonhealed...

Piattelli A, Scarano A, Piattelli M. Microscopical aspects of failure in osseointegrated dental implants: a report of five cases. Biomaterials [Internet]. 1996;17(12):1235–41. [cited 2015 Oct 5] Available from: http://www.sciencedirect.com/science/article/pii/0142961296849441. Stajčić Z, Stojčev Stajčić LJ, Kalanović M, Đinić A, Divekar N, Rodić M, et al. Removal of dental implants: re...

References : Twist removal of healed vs. nonhealed...

Assenza B, Scarano A, Perrotti V, Vozza I, Quaranta A, Quaranta M, et al. Peri-implant bone reactions around immediately loaded conical implants with different prosthetic suprastructures: Histological and histomorphometrical study on minipigs. Clin Oral Investig. 2010;14(3):285–90. Sasaki H, Koyama S, Yokoyama M, Yamaguchi K, Itoh M SK. Bone metabolic activity around dental implants under loadi...

References : Twist removal of healed vs. nonhealed...

Glauser R, Sailer I, Wohlwend A, Studer S, Schibli M, Schärer P. Experimental zirconia abutments for implant-supported single-tooth restorations in esthetically demanding regions: 4-year results of a prospective clinical study. Int J Prosthodont [Internet]. 2004;17(3):285–90. [cited 2015 Oct 6] Available from: http://www.mendeley.com/catalog/experimental-zirconia-abutments-implantsupported-sing...

References : Twist removal of healed vs. nonhealed...

Brånemark PI. Osseointegration and its experimental background. J Prosthet Dent. 1983;50(3):399–410. Chiapasco M, Gatti C. Immediate loading of dental implants placed in revascularized fibula free flaps: a clinical report on 2 consecutive patients. Int J Oral Maxillofac Implants. 2015;19(6):906–12. Shemtov-Yona K, Rittel D. On the mechanical integrity of retrieved dental implants. J Mech Be...

Conclusion : Twist removal of healed vs. nonhealed...

Implant removal torque should be higher to remove implants with long-time installation than implants removed immediately after installation. Although, removal torque causes microscopical fractures and smooth on the peri-implant bone grooves, it does not compromised the bone healing.

Discussion : Twist removal of healed vs. nonhealed...

According to Christenson R.H. [24], the bone structure, metabolism, and regulation are reflected by markers of resorption, formation, and/or turnover. Among the markers of bone resorption is the type 1 collagen degradation and maker of bone formation: Osteocalcin. Bone formation markers derive from the osteoblastic activity, formed during the different stages of osteoblasts proliferation, differen...

Discussion : Twist removal of healed vs. nonhealed...

In order to better use a model which reproduce the natural conditions of dental implant in action, minipigs (BR-1) have been used in this study [44], the nonprimate animal model that is most appropriate for the study of human mastication [45] and commonly used in research because suine and human share important anatomic and physiologic characteristics [46, 47]. The osseointegration process is qui...

Discussion : Twist removal of healed vs. nonhealed...

Dental implant revolutionized oral rehabilitation, becoming the natural teeth replacement by a titanium implant, a successful alternative to treat total or partial edentulism [14, 26, 27]. Nowadays, dental implants are definitely a current procedure in many dental offices [3, 28, 29]. Despite the long-term success shown by different studies [14, 30], implant failure is inevitable [31–33]. Since,...

Results : Twist removal of healed vs. nonhealed im...

Duplicate sections of peri-impant bone were obtained from each implant sample to evaluate the percentage of stained areas in order to differentiate markers of collagen I and osteocalcin within both experimental conditions (Fig. 6). The highest collagen I expression values were observed at the IR experimental condition, and osteocalcin expression was higher at the 9M. There was a statistically si...

Results : Twist removal of healed vs. nonhealed im...

No remarkable complications were found during the healing period. At sacrifice, all 18 implants fixed after 9 months were considered successfully integrated at the time of the removal and none showed any mobility or signal of infection at sacrifice. There was no difference in the healing between animals who had the implants immediately removed after installation, and animal whose implants were re...

Materials and methods : Twist removal of healed vs...

Hematoxylin-eosin-stained section images were digitized and analyzed in order to recognize the presence of native bone tissue by the presence of osteocyte lacunae-containing cells and the newly formed bone tissue recognized by the absence of lacunae. Also, the characteristics of peri-implant bone, presence or absence of bone fractures, and the shape and contour of bone grooving resultant of the tr...

Materials and methods : Twist removal of healed vs...

The mandibles were sectioned into left and right segments, and each peri-implant bone was sectioned again to individualize them. Each peri-implant bone block was fixed in buffered formalin solution, pH 7.0, for 6 days, demineralized in 10% formic acid, and dehydrated through progressing alcohol concentrations and paraffin-embedded. Paraffin blocks were sectioned at 7-μm thick mounted on poly-l-...

Materials and methods : Twist removal of healed vs...

This study was approved by the University Animal Ethics Committee-CEUA/UNICAMP-(Campinas, SP) (no.2730-1/12). Six adult male mini pigs (BR-1 mini pigs, São Paulo, Brazil) with ~36 months old and weighed ~55 kg were used in the experiment. The mini pigs were kept in the Experimental Center of the Veterinary Faculty (FESB-Bragança Paulista, SP) and were allowed to adapt to the environment 1 wee...

Introduction : Twist removal of healed vs. nonheal...

Many authors investigated bone reactions around dental implants [17–21]. What happens in the peri-implant bone implants removed is not reported in scientific articles. This study evaluated the peri-implant bone after his immediate removal and after 9 months of osseointegration. The aim of the present study was to evaluate the peri-implant bone after dental implant removal.

Introduction : Twist removal of healed vs. nonheal...

Since the discovery of osseointegration by Branemark in Sweden in 1960, where found that when titanium screws left undisturbed in bone, the osteocytes grow in close apposition to the titanium surfaces and provide firm anchorage. This discovery was successfully applied in dental and craniofacial reconstructive surgery in 1965 [1, 2]. Dental implants became a common procedure in the modern dental tr...

Abstract : Twist removal of healed vs. nonhealed i...

The objective of this study was to evaluate the effect of removal torque (reverse torque) of titanium implants in peri-implant bone. The P1-M1 teeth were extracted bilaterally of 6 mini pigs (BR-1). Each animal received 6 titanium implants, three for each side of mandible. On the right side of mandible, 3 implants reminded 9 months (9M) under masticatory activity and on the left side, other 3 im...

Table 1 Implant characteristics—insertion region...

Patient Implant region (FDI) Implant parameters Dimensions of implant Diameter [mm]/length [mm] ...

About this article : Vitamin D deficiency in early...

Fretwurst, T., Grunert, S., Woelber, J.P. et al. Vitamin D deficiency in early implant failure: two case reports. Int J Implant Dent 2, 24 (2016). https://doi.org/10.1186/s40729-016-0056-0 Download citation Received: 04 August 2016 Accepted: 16 November 2016 Published: 25 November 2016 DOI: https://doi.org/10.1186/s40729-016-0056-0

Rights and permissions : Vitamin D deficiency in e...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Vitamin D deficiency in early...

Department of Oral- and Craniomaxillofacial Surgery, Center for Dental Medicine, University Medical Center Freiburg, Hugstetter Straße 55, Freiburg, D-79106, Germany Tobias Fretwurst, Sebastian Grunert, Katja Nelson & Wiebke Semper-Hogg Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, USA Tobias Fretwurst Department of Operative Dentistr...

Acknowledgements : Vitamin D deficiency in early i...

We would like to thank Dr. John Nelson for his resourceful and constructive ideas. The authors Tobias Fretwurst, Sebastian Grunert, Johan Woelber, Katja Nelson, and Wiebke Semper-Hogg declare no conflicts of interest with respect to the research, authorship, and/or publication of this article. The authors Tobias Fretwurst, Sebastian Grunert, Johan Woelber, Katja Nelson, and Wiebke Semper-Hogg do...

References : Vitamin D deficiency in early implant...

Di Rosa M, Malaguarnera M, Nicoletti F, Malaguarnera L. Vitamin D3: a helpful immuno-modulator. Immunology. 2011;134(2):123–39. Download references

References : Vitamin D deficiency in early implant...

Kikuta J, Kawamura S, Okiji F, Shirazaki M, Sakai S, Saito H, Ishii M. Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D. Proc Natl Acad Sci U S A. 2013;110(17):7009–13. Hewison M, Freeman L, Hughes SV, Evans KN, Bland R, Eliopoulos AG, Kilby MD, Moss PA, Chakraverty R. Differential regulatio...

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Hong HH, Chou TA, Yang JC, Chang CJ. The potential effects of cholecalciferol on bone regeneration in dogs. Clin Oral Implants Res. 2012;23(10):1187–92. Hong HH, Yen TH, Hong A, Chou TA. Association of vitamin D3 with alveolar bone regeneration in dogs. J Cell Mol Med. 2015;19(6):1208–17. Schulze-Späte U, Dietrich T, Wu C, Wang K, Hasturk H, Dibart S. Systemic vitamin D supplementation and ...

References : Vitamin D deficiency in early implant...

Gallagher JC, Sai AJ. Vitamin D insufficiency, deficiency, and bone health. J Clin Endocrinol Metab. 2010;95(6):2630–3. Ning Z, Song S, Miao L, Zhang P, Wang X, Liu J, Hu Y, Xu Y, Zhao T, Liang Y, Wang Q, Liu L, Zhang J, Hu L, Huo M, Zhou Q. High prevalence of vitamin D deficiency in urban health checkup population. Clin Nutr. 2016;35(4):859–63. Spiro A, Buttriss JL. Vitamin D: an overview o...

References : Vitamin D deficiency in early implant...

Maier GS, Horas K, Seeger JB, Roth KE, Kurth AA, Maus U. Is there an association between periprosthetic joint infection and low vitamin D levels? Int Orthop. 2014;38(7):1499–504. Alvim-Pereira F, Montes CC, Thomé G, Olandoski M, Trevilatto PC. Analysis of association of clinical aspects and vitamin D receptor gene polymorphism with dental implant loss. Clin Oral Implants Res. 2008;19(8):786–...

References : Vitamin D deficiency in early implant...

Esposito M, Thomsen P, Ericson LE, Lekholm U. Histopathologic observations on early oral implant failures. Int J Oral Maxillofac Implants. 1999;14:798–810. Olmedo-Gaya MV, Manzano-Moreno FJ, Cañaveral-Cavero E, de Dios Luna-Del Castillo J, Vallecillo-Capilla M. Risk factors associated with early implant failure: a 5-year retrospective clinical study. J Prosthet Dent. 2016;115(2):150–5. Wenn...

Conclusions : Vitamin D deficiency in early implan...

To overcome the shortcomings of this case reports, prospective, multicenter, and controlled studies must follow to affirm a potential relationship between vitamin D deficiency, osteoimmunology, and the early failure of dental implants. Currently, a general recommendation for a standardized vitamin D screening in dental implantology cannot be stated due to lack of evidence.

Case presentation : Vitamin D deficiency in early ...

Nevertheless, the vitamin D deficiency prevalence in the European population indicates that a vitamin D deficiency is probably not a sole causative factor for early implant failure; otherwise, the early implant failure rate would be significantly higher. However, a synergistic effect with other factors is conceivable. Some authors stated that implant osseointegration is not simply a wound healing ...

Case presentation : Vitamin D deficiency in early ...

Local and systemic factors can affect the survival rate of dental implants [30–33]. The causes of early implant failure are not fully clarified and an association between vitamin D and dental implant osseointegration has not been investigated properly [8, 13–16]. Some recent animal studies in rodents demonstrated a relationship between vitamin D supplementation and an increased bone to implant...

Case presentation : Vitamin D deficiency in early ...

In this 51-year-old male patient, no grafting procedure was performed as vertical and horizontal alveolar ridge dimension was adequate for implant placement. The implant placement in regions 36 and 37 was performed as guided surgery (Fig. 2a, Table 1). The implant placement was uneventful and the bone appeared clinically healthy. A cortical bone profiling was performed during implant placement. ...

Case presentation : Vitamin D deficiency in early ...

The medical history of this 48-year-old male patient showed a high blood pressure; otherwise, the patient was healthy. A successfully completed periodontal therapy was done before implant therapy. The patient demonstrated stable marginal bone levels. Autologous retromolar bone grafting using local anesthesia was performed in the left mandible (see Fig. 1a). This patient received a postoperative o...

Case presentation : Vitamin D deficiency in early ...

Patients treated consecutively in one center (Department of Oral- and Craniomaxillofacial Surgery, University Medical Center Freiburg). None of the patients showed systemic disease. Both patients did not take regular medication and were negative for alcohol, nicotine, and drug use. Bothe male patients (48 and 51 years of age) were not immunosuppressed, irradiated or received chemotherapy. Written...

Background : Vitamin D deficiency in early implant...

Long-term stable osseointegrated implants are the primary goal in dental implantology. Although dental implants have proven clinical reliable in the long term, the failure of implants at a very early stage of osseointegration has been described [1, 2]. The pursuit to identify the mechanisms leading to early implant failure is ongoing to date and include the following: tobacco usage, diabetes, wear...

Abstract : Vitamin D deficiency in early implant f...

An association between vitamin D deficiency and early dental implant failure is not properly verified, but its role in osteoimmunology is discussed. This article illustrates two case reports with vitamin D deficiency and early implant failure. Prior to implant placement, the first patient received crestal bone grafting with autologous material. Both patients received dental implants from different...

Fig. 4. Kaplan-Meier implant survival curves for b...

Fig. 4. Kaplan-Meier implant survival curves for bone and bone substitutes Fig. 4. Kaplan-Meier implant survival curves for bone and bone substitutes

Fig. 3. Kaplan-Meier survival curves for membrane ...

Fig. 3. Kaplan-Meier survival curves for membrane types Fig. 3. Kaplan-Meier survival curves for membrane types

Fig. 2. Kaplan-Meier implant survival curves for a...

Fig. 2. Kaplan-Meier implant survival curves for augmentation procedures Fig. 2. Kaplan-Meier implant survival curves for augmentation procedures

Fig. 8. There were moderately significant and posi...

Fig. 8. There were moderately significant and positive correlations between the ALP levels and OC levels at all measurements from week 1 to week 12. The OC levels in pg/μg protein were associated with the ALP levels in nM/μg protein at the implant site (a), control site (b), and pooled samples of the control and implant sites (c) Fig. 8. There were moderately significant and positive correl...

Fig. 7. Comparison between the trend of the biomar...

Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time

Fig. 6. There were weakly significant and positive...

Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all measurements from week 1 to week 12. At the implant site, the ALP levels in nM/μg protein (a) or the OC levels in pg/μg protein (b) were associated with ISQ values Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all...

Fig. 5. Change in the median values of the OC leve...

Fig. 5. Change in the median values of the OC level over time. In the test group, the OC level continuously increased with time. There was a statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Fig. 4. Change in the median values of the ALP lev...

Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level decreased at 1–4 weeks and then increased at 6, 8, 10, and 12 weeks. There was no statistically significant difference in the ALP level in either the control or the test groups at any measurement Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level d...

Fig. 3. Change in the median values of the GCF (co...

Fig. 3. Change in the median values of the GCF (control group) and PICF (test group) volume over time. In the test group, the PICF volume continuously decreased with time (a). There were no significant differences in the median values of the crevicular fluid volume in either the control group or the test groups at any measurement (b) Fig. 3. Change in the median values of the GCF (control gro...

Fig. 2. Change in the mean ISQ values over time. T...

Fig. 2. Change in the mean ISQ values over time. There was a statistically significant decrease in the mean ISQ values between 1 and 3 weeks (P 

Fig. 1. Timeline of the clinical study. I—implan...

Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth

Table 5 Crevicular fluid ALP and OC levels : Relat...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Median (interquartile range) ALP level  (nM/μg protein)   Tooth (control) 175 (215) 203 (308) 148 (269) 143 (112) 266 (427) 145 (96) 181 (148) 191 (263) 107 (128)   Implant (test) 230 (238) 139 (139) 157 (293) 108 (134) 166 (434) 179 (251) 147 (...

Table 4 Crevicular fluid volume : Relation between...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Median (interquartile range) CF volume (μl)  Tooth (control) 0.20 (0.23) 0.26 (0.25) 0.19 (0.20) 0.19 (0.50) 0.17 (0.33) 0.18 (0.08) 0.13 (0.24) 0.23 (0.42) 0.20 (0.17)  Implant (test) 0.26 (0.30) 0.25 (0.41) 0.16 (0.21) 0.17 (0.19) 0.18 (0.33) 0.13 (0.14) ...

Table 3 ISQ values according to gender and bone qu...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks...

Table 2 Profile of patients : Relation between the...

Patient no. Age Sex Positiona Bone qualityb 1 34 ...

Table 1 Inclusion and exclusion criteria : Relatio...

Inclusion criteria Exclusion criteria Patients aged 25–65 years Presence of periodontal disease or periapical lesions Ability to participat...

About this article : Relation between the stabilit...

Tirachaimongkol, C., Pothacharoen, P., Reichart, P.A. et al. Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study. Int J Implant Dent 2, 27 (2016). https://doi.org/10.1186/s40729-016-0058-y Download citation Received: 14 September 2016 Accepted: 18 November 2016 Published: 08 December 2016 DOI...

Rights and permissions : Relation between the stab...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Relation between the stabilit...

Center of Excellence for Dental Implantology, Faculty of Dentistry, Chiang Mai University, Suthep sub-district, A. Muang, Chiang Mai, 50200, Thailand Choknapa Tirachaimongkol & Pathawee Khongkhunthian Department of Biochemistry, Faculty of Medicine, Thailand Excellence Center for Tissue Engineering and Stem Cells, Chiang Mai, Thailand Peraphan Pothacharoen Department of Oral Medicine, Dental...

Acknowledgements : Relation between the stability ...

The authors acknowledge Mrs. Yupaporn Kiatsakulcharoen and Miss Kamolwan Mangkalad, the Center of Excellent for Dental Implantology, Chiang Mai University for clinical assistance, Mr. Aitthiphon Chongchai, the Department of Biochemistry, Faculty of Medicine Chiang Mai University for laboratory assistance, Dr.Thanapat Sastraruji, Faculty of Dentistry, Chiang Mai University for statistical consultat...

References : Relation between the stability of den...

Lekholm U, Zarb G, Albrektsson T. Tissue integrated prostheses. Patient selection and preparation. Chicago: Quintessence Publishing Co Inc; 1985. p. 199–209. Download references

References : Relation between the stability of den...

Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 2003;3:251–62. Emecen-Huja P, Eubank TD, Shapiro V, Yildiz V, Tatakis DN, Leblebicioglu B. Peri-implant versus periodontal wound healing. J Clin Periodontol. 2013;40:816–24. Chapple LLC, Socransky SS, Dibart S, Glenwright DH, Matthews JB. Chemiluminescent as...

References : Relation between the stability of den...

Bischof M, Nedir R, Szmukler-Moncler S, Bernard JP, Samson J. Implant stability measurement of delayed and immediately loaded implants during healing. Clin Oral Implants Res. 2004;5:529–39. Sim CPC, Lang NP. Factors influencing resonance frequency analysis assessed by Osstell mentor during implant tissue integration: I. Instrument positioning, bone structure, implant length. Clin Oral Implants ...

References : Relation between the stability of den...

Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155–70. Khongkhunthian P. Implant features. In: Khongkhunthian P, editor. PW Plus Thai Dental Implant. Bangkok: STZ Mospace design; 2015. p. 12. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, ...

Conclusions : Relation between the stability of de...

Within the limitations of this study and cautious interpretation due to small number of implants/patients, the ISQ values were weakly correlated with both ALP and OC molecules in PICF during the healing period. The results also show that osteocalcin may be used as a biological marker for monitoring implant healing at 6, 8, 10, and 12 weeks after implant placement. The ISQ values showed high stabi...

Discussion : Relation between the stability of den...

Vogel and Marcotte [33] suggested that the correlation between mRNA and protein quantities is approximately 40%. As there are many mechanisms between transcription and translation, especially in human cell and protein stability, at the gene expression level, the transcription data is beneficial in making decisions about molecular candidates for future studies at the protein level. The colorimetric...

Discussion : Relation between the stability of den...

The main sources of ALP in GCF are neutrophils, bacteria within dental plaque, fibroblasts, and osteoblasts [28]. Plagnat et al. [29] suggested that longitudinal monitoring of ALP in PICF might confirm its possible use as a marker of implant failure. Considering the change in the median values of the ALP level over time, in the test group, the ALP level decreased at 1–4 weeks and then increased...

Results : Relation between the stability of dental...

At the implant site, the OC level continuously increased with time. According to the Friedman followed by Wilcoxon signed-rank tests, there was statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Results : Relation between the stability of dental...

Ten patients, seven females, and three males, aged 42.4 ± 11.99 years (range, 28 to 64 years), with either a first mandibular or second mandibular molar edentulous area, who required a single nonsubmerged implant participated in this study, as shown in Table 2. The implants used for all patients were 10 mm long and 5 mm in diameter. All patients completed the follow-up. None of the impla...

Methods : Relation between the stability of dental...

Data were analyzed by using SPSS 17.0 software (SPSS Inc., Chicago, IL, USA). Repeated measures analysis of variance was performed to evaluate the change in the ISQ values at each measurement. The independent samples t test was used to investigate the differences in implant stability in the patients’ gender and bone quality. The Friedman test, followed by the Wilcoxon signed-rank test, was used ...

Methods : Relation between the stability of dental...

The level of OC was measured by using commercially available ELISA kits (Human Osteocalcin Quantikine ELISA Kit, R&D Systems, Inc., Minneapolis, MN, USA) according to the manufacturer’s instructions. A 100 μl volume of Assay Diluent RD1-117 (R&D Systems) was added into each well of the microplate and then 50 μl of standard (0–64 ng/ml) or sample was added to each well. The microplate was ...

Methods : Relation between the stability of dental...

To observe the level of two bone formation biomarkers (alkaline phosphatase and osteocalcin) during the osseointegration period compared with control group using GCF from the first molar of the contralateral side of implant position, the sample collection of GCF was performed before the surgical procedure, immediately after the surgical operation and after 1, 2, 3, 4, 6, 8, 10, and 12 weeks. The ...

Methods : Relation between the stability of dental...

The study is a prospective clinical study during the 3-month healing period of implant. The study was approved by the Human Experimentation Committee, Faculty of Dentistry, Chiang Mai University. The study outline is shown in Fig. 1. Ten patients, who were partially edentulous in the mandibular posterior region for whom a single nonsubmerged implant was planned, participated in this study. All o...

Background : Relation between the stability of den...

Osteocalcin (OC) is the most plentiful noncollagenous protein of the bone matrix. It is secreted from odontoblasts, osteocytes, and osteoblasts, in order to bind hydroxyapatite and calcium during matrix mineralization [7]. It is one of the serological markers in the bone formation process. Numerous studies have shown increased OC levels in bone formation. However, increased OC level relates more t...

Background : Relation between the stability of den...

Dental implants have shown a high success rate for rehabilitation of edentulous patients if certain conditions are met during treatment. Nevertheless, the risk of failure remains difficult to predict. The achievement of osseointegration depends on many factors, such as a suitable host, biocompatible materials, careful surgery, and an appropriate healing time [1]. The primary stability comes from ...

Abstract : Relation between the stability of denta...

The purposes of this study were to examine the correlation between the stability of dental implants and bone formation markers during the healing period and to monitor the stability of dental implants using the resonance frequency analysis (RFA) method. The null hypothesis of the study is no correlation between the stability of dental implant and bone formation markers. The study is a prospective...

Fig. 8. There were moderately significant and posi...

Fig. 8. There were moderately significant and positive correlations between the ALP levels and OC levels at all measurements from week 1 to week 12. The OC levels in pg/μg protein were associated with the ALP levels in nM/μg protein at the implant site (a), control site (b), and pooled samples of the control and implant sites (c) Fig. 8. There were moderately significant and positive correl...

Fig. 7. Comparison between the trend of the biomar...

Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time

Fig. 6. There were weakly significant and positive...

Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all measurements from week 1 to week 12. At the implant site, the ALP levels in nM/μg protein (a) or the OC levels in pg/μg protein (b) were associated with ISQ values Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all...

Fig. 5. Change in the median values of the OC leve...

Fig. 5. Change in the median values of the OC level over time. In the test group, the OC level continuously increased with time. There was a statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Fig. 4. Change in the median values of the ALP lev...

Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level decreased at 1–4 weeks and then increased at 6, 8, 10, and 12 weeks. There was no statistically significant difference in the ALP level in either the control or the test groups at any measurement Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level d...

Fig. 3. Change in the median values of the GCF (co...

Fig. 3. Change in the median values of the GCF (control group) and PICF (test group) volume over time. In the test group, the PICF volume continuously decreased with time (a). There were no significant differences in the median values of the crevicular fluid volume in either the control group or the test groups at any measurement (b) Fig. 3. Change in the median values of the GCF (control gro...

Fig. 2. Change in the mean ISQ values over time. T...

Fig. 2. Change in the mean ISQ values over time. There was a statistically significant decrease in the mean ISQ values between 1 and 3 weeks (P 

Fig. 1. Timeline of the clinical study. I—implan...

Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth

Table 5 Crevicular fluid ALP and OC levels : Relat...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Median (interquartile range) ALP level  (nM/μg protein)   Tooth (control) 175 (215) 203 (308) 148 (269) 143 (112) 266 (427) 145 (96) 181 (148) 191 (263) 107 (128)   Implant (test) 230 (238) 139 (139) 157 (293) 108 (134) 166 (434) 179 (251) 147 (...

Table 4 Crevicular fluid volume : Relation between...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Median (interquartile range) CF volume (μl)  Tooth (control) 0.20 (0.23) 0.26 (0.25) 0.19 (0.20) 0.19 (0.50) 0.17 (0.33) 0.18 (0.08) 0.13 (0.24) 0.23 (0.42) 0.20 (0.17)  Implant (test) 0.26 (0.30) 0.25 (0.41) 0.16 (0.21) 0.17 (0.19) 0.18 (0.33) 0.13 (0.14) ...

Table 3 ISQ values according to gender and bone qu...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks...

Table 2 Profile of patients : Relation between the...

Patient no. Age Sex Positiona Bone qualityb 1 34 Female 46 3 2 38 Female 36 3 3 43 Female 37 3 4 64 Male 46 2 5 30 Female 47 3 6 48 Female 36 2 7 57 Male 36 3 8 28 Female 46 3 9 33 Male 46 2 10 49 Female 46 3   Table 2 Profile of patients

Table 1 Inclusion and exclusion criteria : Relatio...

Inclusion criteria Exclusion criteria Patients aged 25–65 years Presence of periodontal disease or periapical lesions Ability to participat...

About this article : Relation between the stabilit...

Tirachaimongkol, C., Pothacharoen, P., Reichart, P.A. et al. Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study. Int J Implant Dent 2, 27 (2016). https://doi.org/10.1186/s40729-016-0058-y Download citation Received: 14 September 2016 Accepted: 18 November 2016 Published: 08 December 2016 DOI: https://doi.org/10....

Rights and permissions : Relation between the stab...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Relation between the stabilit...

Center of Excellence for Dental Implantology, Faculty of Dentistry, Chiang Mai University, Suthep sub-district, A. Muang, Chiang Mai, 50200, Thailand Choknapa Tirachaimongkol & Pathawee Khongkhunthian Department of Biochemistry, Faculty of Medicine, Thailand Excellence Center for Tissue Engineering and Stem Cells, Chiang Mai, Thailand Peraphan Pothacharoen Department of Oral Medicine, Dental...

Acknowledgements : Relation between the stability ...

The authors acknowledge Mrs. Yupaporn Kiatsakulcharoen and Miss Kamolwan Mangkalad, the Center of Excellent for Dental Implantology, Chiang Mai University for clinical assistance, Mr. Aitthiphon Chongchai, the Department of Biochemistry, Faculty of Medicine Chiang Mai University for laboratory assistance, Dr.Thanapat Sastraruji, Faculty of Dentistry, Chiang Mai University for statistical consultat...

References : Relation between the stability of den...

Lekholm U, Zarb G, Albrektsson T. Tissue integrated prostheses. Patient selection and preparation. Chicago: Quintessence Publishing Co Inc; 1985. p. 199–209. Download references

References : Relation between the stability of den...

Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 2003;3:251–62. Emecen-Huja P, Eubank TD, Shapiro V, Yildiz V, Tatakis DN, Leblebicioglu B. Peri-implant versus periodontal wound healing. J Clin Periodontol. 2013;40:816–24. Chapple LLC, Socransky SS, Dibart S, Glenwright DH, Matthews JB. Chemiluminescent as...

References : Relation between the stability of den...

Bischof M, Nedir R, Szmukler-Moncler S, Bernard JP, Samson J. Implant stability measurement of delayed and immediately loaded implants during healing. Clin Oral Implants Res. 2004;5:529–39. Sim CPC, Lang NP. Factors influencing resonance frequency analysis assessed by Osstell mentor during implant tissue integration: I. Instrument positioning, bone structure, implant length. Clin Oral Implants ...

References : Relation between the stability of den...

Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155–70. Khongkhunthian P. Implant features. In: Khongkhunthian P, editor. PW Plus Thai Dental Implant. Bangkok: STZ Mospace design; 2015. p. 12. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, ...

Conclusions : Relation between the stability of de...

Within the limitations of this study and cautious interpretation due to small number of implants/patients, the ISQ values were weakly correlated with both ALP and OC molecules in PICF during the healing period. The results also show that osteocalcin may be used as a biological marker for monitoring implant healing at 6, 8, 10, and 12 weeks after implant placement. The ISQ values showed high stabi...

Discussion : Relation between the stability of den...

Vogel and Marcotte [33] suggested that the correlation between mRNA and protein quantities is approximately 40%. As there are many mechanisms between transcription and translation, especially in human cell and protein stability, at the gene expression level, the transcription data is beneficial in making decisions about molecular candidates for future studies at the protein level. The colorimetric...

Discussion : Relation between the stability of den...

The main sources of ALP in GCF are neutrophils, bacteria within dental plaque, fibroblasts, and osteoblasts [28]. Plagnat et al. [29] suggested that longitudinal monitoring of ALP in PICF might confirm its possible use as a marker of implant failure. Considering the change in the median values of the ALP level over time, in the test group, the ALP level decreased at 1–4 weeks and then increased...

Discussion : Relation between the stability of den...

The results of this study show that, at the time of implantation, the ISQ values ranged between 67.5 and 83. The mean initial ISQ value was 77.0 ± 1.32. These findings are in harmony with those of previous studies [16, 18]. Tallarico et al. (2011) reported that the macro-design of dental implant affects the primary anchorage [16]. They suggested that the high initial ISQ value is a factor in ...

Results : Relation between the stability of dental...

At the implant site, the OC level continuously increased with time. According to the Friedman followed by Wilcoxon signed-rank tests, there was statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Results : Relation between the stability of dental...

Ten patients, seven females, and three males, aged 42.4 ± 11.99 years (range, 28 to 64 years), with either a first mandibular or second mandibular molar edentulous area, who required a single nonsubmerged implant participated in this study, as shown in Table 2. The implants used for all patients were 10 mm long and 5 mm in diameter. All patients completed the follow-up. None of the impla...

Methods : Relation between the stability of dental...

Data were analyzed by using SPSS 17.0 software (SPSS Inc., Chicago, IL, USA). Repeated measures analysis of variance was performed to evaluate the change in the ISQ values at each measurement. The independent samples t test was used to investigate the differences in implant stability in the patients’ gender and bone quality. The Friedman test, followed by the Wilcoxon signed-rank test, was used ...

Methods : Relation between the stability of dental...

The level of OC was measured by using commercially available ELISA kits (Human Osteocalcin Quantikine ELISA Kit, R&D Systems, Inc., Minneapolis, MN, USA) according to the manufacturer’s instructions. A 100 μl volume of Assay Diluent RD1-117 (R&D Systems) was added into each well of the microplate and then 50 μl of standard (0–64 ng/ml) or sample was added to each well. The microplate was ...

Methods : Relation between the stability of dental...

To observe the level of two bone formation biomarkers (alkaline phosphatase and osteocalcin) during the osseointegration period compared with control group using GCF from the first molar of the contralateral side of implant position, the sample collection of GCF was performed before the surgical procedure, immediately after the surgical operation and after 1, 2, 3, 4, 6, 8, 10, and 12 weeks. The ...

Methods : Relation between the stability of dental...

The study is a prospective clinical study during the 3-month healing period of implant. The study was approved by the Human Experimentation Committee, Faculty of Dentistry, Chiang Mai University. The study outline is shown in Fig. 1. Ten patients, who were partially edentulous in the mandibular posterior region for whom a single nonsubmerged implant was planned, participated in this study. All o...

Background : Relation between the stability of den...

Osteocalcin (OC) is the most plentiful noncollagenous protein of the bone matrix. It is secreted from odontoblasts, osteocytes, and osteoblasts, in order to bind hydroxyapatite and calcium during matrix mineralization [7]. It is one of the serological markers in the bone formation process. Numerous studies have shown increased OC levels in bone formation. However, increased OC level relates more t...

Background : Relation between the stability of den...

Dental implants have shown a high success rate for rehabilitation of edentulous patients if certain conditions are met during treatment. Nevertheless, the risk of failure remains difficult to predict. The achievement of osseointegration depends on many factors, such as a suitable host, biocompatible materials, careful surgery, and an appropriate healing time [1]. The primary stability comes from ...

Abstract : Relation between the stability of denta...

The purposes of this study were to examine the correlation between the stability of dental implants and bone formation markers during the healing period and to monitor the stability of dental implants using the resonance frequency analysis (RFA) method. The null hypothesis of the study is no correlation between the stability of dental implant and bone formation markers. The study is a prospective...

Fig. 2. Figure illustrating the proposed mucosal t...

Fig. 2. Figure illustrating the proposed mucosal thickening index. A ≤1 mm, indicating no thickening; B >1 mm but ≤2 mm, indicating minimal thickening; C >2 mm but ≤5 mm, indicating moderate thickening; D >5 mm, indicating severe thickening Fig. 2. Figure illustrating the proposed mucosal thickening index. A ≤1 mm, indicating no thickening; B >1 mm but ≤2 mm, indicating min...

Fig. 1. Figure illustrating the reference points o...

Fig. 1. Figure illustrating the reference points of the CBCT measurements. A: most posterior point of the sinus wall; B: most anterior point of the sinus wall; C: mid-point between A and B; C1: measurement of mucosal thickening perpendicular to A–B line at point C; D: mid-point between A and C; D1: measurement of mucosal thickening perpendicular to A–B line at point D; E: mid-point between B...

Table 2 Statistical results after inter-variable a...

  Gender Respiratory diseases Cardio-vascular diseases Diabetes mellitus Smoking Hist...

Table 1 CBCT measurements of sinus mucosal thicken...

Patient Anterior (E1-floor of the sinus) Middle (C1-floor of the sinus) Posterior (D1-floor of the sinus) ...

About this article : Dental implants and grafting ...

Maska, B., Lin, GH., Othman, A. et al. Dental implants and grafting success remain high despite large variations in maxillary sinus mucosal thickening. Int J Implant Dent 3, 1 (2017). https://doi.org/10.1186/s40729-017-0064-8 Download citation Received: 18 October 2016 Accepted: 13 January 2017 Published: 18 January 2017 DOI: https://doi.org/10.1186/s40729-017-0064-8

Rights and permissions : Dental implants and graft...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Dental implants and grafting ...

You can also search for this author in PubMed Google Scholar Correspondence to Yvonne Kapila.

Author information : Dental implants and grafting ...

Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, 1011 N University Ave, Ann Arbor, MI, USA Bartosz Maska, Guo-Hao Lin, Abdullah Othman, Shabnam Behdin, Suncica Travan, Erika Benavides & Yvonne Kapila Department of Surgical Sciences, School of Dentistry, Marquette University, 1801 W Wisconsin Ave, Milwaukee, WI, USA Guo-Hao Lin Department of Peri...

Acknowledgements : Dental implants and grafting su...

The authors thank Ms. Victoria Zakrzewski for her help with the figure generation and preparation. Co-primary author BM contributed to the CBCT measurement and preparation of the manuscript. Co-primary author G-HL contributed to the data analysis and preparation of the manuscript. Second author AO contributed to the protocol preparation, case review, case selection, and preparation of the manuscr...

References : Dental implants and grafting success ...

Romanos GE, Froum S, Costa-Martins S, Meitner S, Tarnow DP. Implant periapical lesions: etiology and treatment options. J Oral Implantol. 2011;37:53–63. Acharya A, Hao J, Mattheos N, Chau A, Shirke P, Lang NP. Residual ridge dimensions at edentulous maxillary first molar sites and periodontal bone loss among two ethnic cohorts seeking tooth replacement. Clin Oral Implants Res. 2014;25:1386–94...

References : Dental implants and grafting success ...

Pazera P, Bornstein MM, Pazera A, Sendi P, Katsaros C. Incidental maxillary sinus findings in orthodontic patients: a radiographic analysis using cone-beam computed tomography (CBCT). Orthod Craniofac Res. 2011;14:17–24. Ritter L, Lutz J, Neugebauer J, et al. Prevalence of pathologic findings in the maxillary sinus in cone-beam computerized tomography. Oral Surg Oral Med Oral Pathol Oral Radiol...

References : Dental implants and grafting success ...

Gardner DG. Pseudocysts and retention cysts of the maxillary sinus. Oral Surg Oral Med Oral Pathol. 1984;58:561–7. Chiapasco M, Palombo D. Sinus grafting and simultaneous removal of large antral pseudocysts of the maxillary sinus with a micro-invasive intraoral access. Int J Oral Maxillofac Surg. 2015;44:1499–505. Cano J, Campo J, Alobera MA, Baca R. Surgical ciliated cyst of the maxilla. Cl...

References : Dental implants and grafting success ...

Beretta M, Poli PP, Grossi GB, Pieroni S, Maiorana C. Long-term survival rate of implants placed in conjunction with 246 sinus floor elevation procedures: results of a 15-year retrospective study. J Dent. 2015;43:78–86. Del Fabbro M, Corbella S, Weinstein T, Ceresoli V, Taschieri S. Implant survival rates after osteotome-mediated maxillary sinus augmentation: a systematic review. Clin Implant D...

Abbreviations : Dental implants and grafting succe...

Cone-beam computed tomographic Protected Health Information Sinus floor elevation

Conclusions : Dental implants and grafting success...

Our study found that the largest tissue thickening was present in the middle section of the maxillary sinus. This tissue thickening did not vary based on gender, age, or smoking status, nor did it relate to the underlying alveolar ridge height. However, patients with a history of periodontal diseases demonstrated a significant association with mucosal thickening. A mucosal thickening index was pro...

Discussion : Dental implants and grafting success ...

Although residual alveolar ridge height has been associated with sinus mucosal thickening [36], our study did not find a significant association between these two parameters. Acharya et al. [36] reported that lower available bone height in the subsinus region was related to thickened sinus membranes within an Asian-Indian and Hong Kong-based Chinese population. Differences in the ethnic compositio...

Discussion : Dental implants and grafting success ...

Based on the findings of the current study, a history of periodontal disease is the only identified parameter significantly associated with sinus mucosal thickening. This finding indicates that clinicians should expect some degree of mucosal thickening when performing sinus augmentation procedures in a previously periodontally involved site. This finding is consistent with several previously publi...

Discussion : Dental implants and grafting success ...

CBCT imaging has been recognized as a more sensitive imaging modality for identifying sinus thickening and pathoses in the posterior maxilla compared to panoramic radiography [21, 22]. This could explain why the current study identified a higher prevalence of mucosal thickening compared to earlier studies [23]. However, compared to other similar CBCT studies [21, 24, 25], the prevalence reported i...

Results : Dental implants and grafting success rem...

Twenty-nine CBCT images (11 females and 18 males) were included in this study. All the implants placed in these included cases survived, representing a 100% implant survival rate. With regards to measurements of mucosal thickening, the intra-examiner reproducibility revealed an exact intra-examiner correlation of 99%, with a p value of 0.40 for a t test for independent samples, indicating a high r...

Methods : Dental implants and grafting success rem...

The sites that were measured are specified in the image below (Fig. 1). The most posterior and anterior aspects of the visible maxillary sinus were measured. The ½ point along with the ¼ and ¾ points were then selected, and the measurements of the mucosal thickening were then completed at these three sites. The thickest portion of the mucosa was also measured if it did not coincide with one of...

Methods : Dental implants and grafting success rem...

The study required access to University of Michigan Protected Health Information (PHI). PHI was necessary in order to track and coordinate the CBCT data and dental and medical history for each subject. Corresponding subject charts and electronic records were reviewed for retrieval of relevant implant placement and restorative history, medical history, and demographic information, including gender ...

Methods : Dental implants and grafting success rem...

Our study hypothesis was that mucosal thickening of more than 2 mm and up to 1/3 of the volume of the sinus would not alter the predictability for SFE and dental implant placement. The primary outcome was to determine the success rate of dental implant placement in augmented maxillary sinus areas with mucosal thickening. A secondary outcome was to evaluate the effect of gender, age, and smoking o...

Background : Dental implants and grafting success ...

Despite the high survival rate of dental implants inserted in maxillary sinuses that have undergone sinus floor elevation (SFE) with bone grafting, complications still occur [1–3]. Sinus membrane perforation is reported to be the most common complication [4, 5]. Postoperative maxillary sinusitis is less common (0–22%) [6, 7]; nevertheless, it could potentially compromise the outcome of SFE and...

Abstract : Dental implants and grafting success re...

Although mucosal thickening is the most common radiographic finding observed regarding sinus pathology, the knowledge regarding its clinical significance on the outcomes of dental implants and grafting in the maxillary sinuses is still limited. We hypothesized that mucosal thickening would not alter the predictability for sinus floor augmentation and dental implant placement. The purpose of this r...

Fig. 7. Orthopantomograph 2 years after implant p...

Fig. 7. Orthopantomograph 2 years after implant placement

Fig. 6. Clinical picture 2 years after implant pl...

Fig. 6. Clinical picture 2 years after implant placement Fig. 6. Clinical picture 2 years after implant placement

Fig. 5. Occlusal view of implants after vertical r...

Fig. 5. Occlusal view of implants after vertical repositioning of the dental alveolus segment showing proper mesiodistal space and buccolingual spacing Fig. 5. Occlusal view of implants after vertical repositioning of the dental alveolus segment showing proper mesiodistal space and buccolingual spacing

Fig. 4. Vertical repositioning of dental alveolus ...

Fig. 4. Vertical repositioning of dental alveolus segment with placement of dental implants Fig. 4. Vertical repositioning of dental alveolus segment with placement of dental implants

Fig. 3. Direct sinus lift with implant osteotomy p...

Fig. 3. Direct sinus lift with implant osteotomy preparation Fig. 3. Direct sinus lift with implant osteotomy preparation

Fig. 2. Marked incision site for surgical access :...

Fig. 2. Marked incision site for surgical access Fig. 2. Marked incision site for surgical access

Fig. 1. Edentulous site with supra-eruption of opp...

Fig. 1. Edentulous site with supra-eruption of opposing dentition Fig. 1. Edentulous site with supra-eruption of opposing dentition

About this article : Maxillary segmental osteoperi...

Tsegga, T., Wright, T. Maxillary segmental osteoperiosteal flap with simultaneous placement of dental implants: case report of a novel technique. Int J Implant Dent 3, 2 (2017). https://doi.org/10.1186/s40729-017-0067-5 Download citation Received: 06 December 2016 Accepted: 13 January 2017 Published: 19 January 2017 DOI: https://doi.org/10.1186/s40729-017-0067-5

Rights and permissions : Maxillary segmental osteo...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Maxillary segmental osteoperi...

Department of Oral & Maxillofacial Surgery, San Antonio Military Medical Center, 3551 Roger Brooke Dr., Ft. Sam Houston, 78234, TX, USA Tibebu Tsegga & Thomas Wright Department of Oral & Maxilofacial Surgery, Wilford Hall Ambulatory Surgical Center, 2200 Bergquist Dr, Suite 1, Lackland AFB, TX, 78236, USA Tibebu Tsegga & Thomas Wright You can also search for this author in PubMed Google S...

References : Maxillary segmental osteoperiosteal f...

Irinakis T. Efficacy of injectable demineralized bone matrix as graft material during sinus elevation surgery with simultaneous implant placement in the posterior maxilla: clinical evaluation of 49 sinuses. J Oral and Maxillofac Surg. 2011;69:134–41. Chiapasoo M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants. 2009;24:237–69. Jenson...

Conclusions : Maxillary segmental osteoperiosteal ...

This case highlights the evolving variations in dentoalveolar augmentation with an emphasis on concomitant implant placement. In the most traditional sense, a vertical osteoperiosteal flap technique would be bound with a stable basal bone that can be used to anchor simultaneous dental implant placement. Further refinement should consider minimizing crestal reflection and overall labial bone resorp...

Discussion : Maxillary segmental osteoperiosteal f...

A critical appraisal of the gingival architecture in the final end point of this case demonstrates some radiolucency through the soft tissue outlining the platform of the Nobel Biocare TiUnite implant. This would lead us to believe that either the transmucosal bone level placement attempt was inaccurate or excessive reflection of the labial tissue has caused some degree of resorption. This is anot...

Discussion : Maxillary segmental osteoperiosteal f...

A suitable alternative surgical management of this particular case might have been to simply perform an alveoloplasty to produce the desired inter-occlusal clearance and proceed with placement of implant and simultaneous direct sinus lift. That would have left more of the apical portion of the implant within the grafted sinus and possibly modified the location of keratinized band of tissue. The lo...

Case Presentation : Maxillary segmental osteoperio...

A 35-year-old female with a 10-year history of partial acquired edentulism at site numbers 3 and 4 presented to our clinic for dental implant evaluation. Preoperative clinical examination revealed a reproducible intercuspation, well-delineated band of keratinized tissue, and decreased inter-occlusal clearance to allow for optimal dimension of prosthetic crowns (Fig. 1). Radiographs demonstrated e...

Background : Maxillary segmental osteoperiosteal f...

Obtaining proper occlusal clearance to allow for a single unit crown restoration is a fundamental prerequisite for dental implant restoration. Long-standing edentulous sites are often fraught with disuse atrophy and unopposed supra-eruption of the opposing dentition. In the posterior maxillae/mandible, there are vital structures that have to be mobilized in order to allow space for either bone tra...

Abstract : Maxillary segmental osteoperiosteal fla...

Dental restorative space from the opposing dentition requires adequate distance for restorative material for an acceptable restoration. Typically, long-standing edentulous alveolar ridges will have vertical and or horizontal defects that require alveolar ridge augmentation for ideal dental implant restorations. Along with these defects, one will see the opposing dentition supra erupt which can obl...

Fig. 12. Radiographic bone levels three years afte...

Fig. 12. Radiographic bone levels three years after placement. Bone levels remain unchanged during long-term follow-up Fig. 12. Radiographic bone levels three years after placement. Bone levels remain unchanged during long-term follow-up

Fig. 11. Implant restoration. Implants were restor...

Fig. 11. Implant restoration. Implants were restored by dental students supervised by prosthodontists at the Dental Center Fig. 11. Implant restoration. Implants were restored by dental students supervised by prosthodontists at the Dental Center

Fig. 10. Palatal approach lateral window sinus aug...

Fig. 10. Palatal approach lateral window sinus augmentation. This photographic series shows the surgical procedure that augmented bone and allowed implant placement at the no. 14 site. a Preoperative view prior to infiltration anesthesia. b Full-thickness midcrestal incision with palatal release and flap elevation. This was aided by a small bony ridge that separated the alveolar crest from the s...

Fig. 9. Schematic diagram of palatal approach sinu...

Fig. 9. Schematic diagram of palatal approach sinus augmentation. The diagram shows the location of the lateral window, avoiding the thick grafted bone on the buccal, and the greater palatal neurovascular bundle Fig. 9. Schematic diagram of palatal approach sinus augmentation. The diagram shows the location of the lateral window, avoiding the thick grafted bone on the buccal, and the greater ...

Fig. 8. Blood supply of the sinus. There are three...

Fig. 8. Blood supply of the sinus. There are three areas in the sinus where blood vessels may be encountered during sinus augmentation procedures for implants. On the inflection point between hard palate and alveolar ridge in the posterior maxilla, the greater palatine neurovascular bundle is located embedded in soft tissue. This inflection point is matched in the internal sinus anatomy and pres...

Fig. 7. Schematic diagram of sinus balloon dilatin...

Fig. 7. Schematic diagram of sinus balloon dilating procedure. This diagram shows how the balloon is inserted into a small transcrestal osteotomy and then expanded with balloon Fig. 7. Schematic diagram of sinus balloon dilating procedure. This diagram shows how the balloon is inserted into a small transcrestal osteotomy and then expanded with balloon

Fig. 6. Right sinus balloon dilation procedure. Th...

Fig. 6. Right sinus balloon dilation procedure. This photographic series shows the surgical procedure that augmented bone and allowed implant placement at the no. 3 site. a Preoperative view after infiltration anesthesia. b Full-thickness midcrestal incision. c Osteotomy preparation with implant drills and osteotomes. d, e The dilating balloon, which is inflated using saline pressure from a syri...

Fig. 5. Left sinus about 12 months after first gr...

Fig. 5. Left sinus about 12 months after first grafting procedure. Cone beam CT imaging shows unusual sinus anatomy after grafting, with finger-like sinus extension at implant site, and thick-grafted bone buccal and apical to it. The infractured wall is still clearly visible, as well as the bovine bone particles used as radiographic marker Fig. 5. Left sinus about 12 months after first graf...

Fig. 4. Right sinus about 12 months after first g...

Fig. 4. Right sinus about 12 months after first grafting procedure. Cone beam CT imaging shows little suitable bone at implant site, but grafted bone displaced distal to site. Bone hydroxyapatite particles were added as radiographic marker to the graft material for the first sinus augmentation procedure and are still visible as radiopaque specks Fig. 4. Right sinus about 12 months after fir...

Fig. 3. Left sinus prior to first sinus grafting p...

Fig. 3. Left sinus prior to first sinus grafting procedure. Cone beam CT imaging also shows very little bone volume on left side for the no. 14 area Fig. 3. Left sinus prior to first sinus grafting procedure. Cone beam CT imaging also shows very little bone volume on left side for the no. 14 area

Fig. 2. Right sinus prior to first sinus grafting ...

Fig. 2. Right sinus prior to first sinus grafting procedure. Cone beam CT imaging shows very little residual bone volume at implant site for the no. 3 area Fig. 2. Right sinus prior to first sinus grafting procedure. Cone beam CT imaging shows very little residual bone volume at implant site for the no. 3 area

Fig. 1. Initial presentation. Panoramic radiograph...

Fig. 1. Initial presentation. Panoramic radiograph taken at initial visit shows severe bone loss, supraerupted molars and furcation involvement Fig. 1. Initial presentation. Panoramic radiograph taken at initial visit shows severe bone loss, supraerupted molars and furcation involvement

About this article : Case report on managing incom...

Boehm, T.K. Case report on managing incomplete bone formation after bilateral sinus augmentation using a palatal approach and a dilating balloon technique. Int J Implant Dent 3, 3 (2017). https://doi.org/10.1186/s40729-017-0065-7 Download citation Received: 08 November 2016 Accepted: 13 January 2017 Published: 19 January 2017 DOI: https://doi.org/10.1186/s40729-017-0065-7

Rights and permissions : Case report on managing i...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Case report on managing incom...

Western University of Health Sciences College of Dental Medicine, 309 E Second Street, Pomona, CA, 91766, USA Tobias K. Boehm You can also search for this author in PubMed Google Scholar Correspondence to Tobias K. Boehm.

Acknowledgements : Case report on managing incompl...

I would like to thank the former dental students Dr. Lily Hoang and Dr. Shirley Hsieh and their prosthodontic supervisors Dr. James Ywom, Dr. Steven Sanders, and Dr. Alessandro Urdaneta for providing this patient’s continued restorative and preventive care after the surgeries and the dental assistants of the Western University of Health Sciences Dental Center, Mrs. Cindy Morton and Mrs. Melody P...

References : Case report on managing incomplete bo...

Penarrocha-Diago M, Galan-Gil S, Carrillo-Garcia C, Penarrocha-Diago D, Penarrocha-Diago M. Transcrestal sinus lift and implant placement using the sinus balloon technique. Med Oral Patol Oral Cir Bucal. 2012;17(1):e122–8. Kfir E, Goldstein M, Abramovitz I, Kfir V, Mazor Z, Kaluski E. The effects of sinus membrane pathology on bone augmentation and procedural outcome using minimal invasive antr...

References : Case report on managing incomplete bo...

Hernandez-Alfaro F, Torradeflot MM, Marti C. Prevalence and management of Schneiderian membrane perforations during sinus-lift procedures. Clin Oral Implants Res. 2008;19(1):91–8. Wallace SS, Mazor Z, Froum SJ, Cho SC, Tarnow DP. Schneiderian membrane perforation rate during sinus elevation using piezosurgery: clinical results of 100 consecutive cases. Int J Periodontics Restorative Dent. 2007;...

Conclusions : Case report on managing incomplete b...

We conclude that incomplete bone formation after sinus augmentation can be managed successfully through a variety of re-entry procedures and that successful long-term implant placement and restoration is possible in a compliant patient of good overall health.

Case presentation : Case report on managing incomp...

Healing was uneventful with little discomfort reported by the patient during the first week, and implant uncovery revealed an implant firmly embedded in bone after 12 months. A third implant was placed at the no. 30 site and supraerupted no. 18 extracted as planned. Restoration of the implants was uneventfully performed by senior dental students supervised by various prosthodontists (Fig. 11). P...

Case presentation : Case report on managing incomp...

For the left side, we decided to access the sinus using a lateral window as the area of deficient bone was much larger in size and more complex in shape. We also decided to approach this area from the palate, as the defect was closer to the palate and required much less bone removal as a buccal approach. Most importantly, we were already familiar with the anatomical structures on the lower medial ...

Case presentation : Case report on managing incomp...

A year later, we requested cone beam computed tomography for both posterior maxilla sites, and we found incomplete bone growth in the sinus. On the right side, bone growth had occurred only distal to the desired implant site, and there was an ovoid extension of sinus into the area planned for implant placement (Fig. 4). On the left side, a finger-like extension of sinus had developed between graf...

Case presentation : Case report on managing incomp...

Lateral window sinus augmentation was performed on each side during appointments spaced 3 months apart, following the technique developed by Tatum in 1974. For each site, a midcrestal mucoperiosteal incision with buccal releases was created, and the lateral Schneiderian membrane of the maxillary sinus exposed through an ovoid window osteotomy of about 15 mm diameter. Osteotomy was performed usin...

Case presentation : Case report on managing incomp...

A 65-year-old retired Caucasian male presented to the Western University of Health Sciences Dental Center expressing an interest in implants after consulting with a private practice periodontist and a dentist from a large implant dentistry practice. He had no medical conditions or known allergies, but reported a 40-pack-year history of using tobacco and quit just before attending the Dental Center...

Background : Case report on managing incomplete bo...

Membrane tears are a significant concern as they may result in postoperative complications such as an oroantral communication as reported recently. In this case, the communication was managed by inserting a fibrin sponge, but it resulted in a cyst-like concavity within grafted bone, which was subsequently managed by re-entry and grafting of the affected site prior to implant placement [14]. As see...

Background : Case report on managing incomplete bo...

Patients with severe periodontal disease often display severely resorbed ridges in the posterior maxilla. Implant therapy can be a challenge for those patients as available bone height is limited by the maxillary sinus. Although sinus augmentation using subantral or lateral window approaches are routinely used, complications occur that may limit bone augmentation in the sinus after any given proce...

Abstract : Case report on managing incomplete bone...

Patients with resorbed edentulous alveolar ridges in the posterior maxilla often require lateral window sinus augmentation procedures prior to implant placement. Lateral window sinus augmentation procedures can produce incomplete bone augmentation as consequence of surgical and healing complications producing unusual and complex sinus anatomy. Although incomplete bone formation after sinus augment...

Fig. 3. ISQ values of MDIs and Ankylos® after eut...

Fig. 3. ISQ values of MDIs and Ankylos® after euthanasia Fig. 3. ISQ values of MDIs and Ankylos® after euthanasia

Fig. 2. ISQ values of MDIs and Ankylos® immediate...

Fig. 2. ISQ values of MDIs and Ankylos® immediately upon insertion Fig. 2. ISQ values of MDIs and Ankylos® immediately upon insertion

Fig. 1. Customized SmartPeg diagrams : Customized ...

Fig. 1. Customized SmartPeg diagrams Fig. 1. Customized SmartPeg diagrams

About this article : Customized SmartPeg for measu...

Dhaliwal, J.S., Albuquerque, R.F., Fakhry, A. et al. Customized SmartPeg for measurement of resonance frequency of mini dental implants. Int J Implant Dent 3, 4 (2017). https://doi.org/10.1186/s40729-017-0066-6 Download citation Received: 09 November 2016 Accepted: 13 January 2017 Published: 01 February 2017 DOI: https://doi.org/10.1186/s40729-017-0066-6

Rights and permissions : Customized SmartPeg for m...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Customized SmartPeg for measu...

Faculty of Dentistry, McGill University, 2001 McGill College Avenue, Suite 500, Montreal, Quebec, H3A 1G1, Canada Jagjit Singh Dhaliwal, Ali Fakhry & Jocelyne S. Feine Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil Rubens F. Albuquerque Jr Department of Zoology, Panjab University, Chandigarh, India Sukhbir Kaur PAPRSB Institute of Health Sci...

References : Customized SmartPeg for measurement o...

Dhaliwal J, Albuquerque R, Murshed, M, Tamimi, F, Feine, JS. A histomorphometric comparison of osseointegration with MDIs and standard implants. IADR/AADR/CADR 91st General Session, Seattle, Washington, USA, March 20–23, 2013 Zix J, Hug S, Kessler-Liechti G, Mericske-Stern R. Measurement of dental implant stability by resonance frequency analysis and damping capacity assessment: comparison of b...

References : Customized SmartPeg for measurement o...

Barros RR, Novaes Jr AB, Muglia VA, Iezzi G, Piattelli A. Influence of interimplant distances and placement depth on peri-implant bone remodeling of adjacent and immediately loaded Morse cone connection implants: a histomorphometric study in dogs. Clin Oral Implants Res. 2010;21(4):371–8. Epub 2010/02/05. Marin C, Bonfante EA, Granato R, Suzuki M, Granjeiro JM, Coelho PG. The effect of alterati...

References : Customized SmartPeg for measurement o...

Meredith N, Book K, Friberg B, Jemt T, Sennerby L. Resonance frequency measurements of implant stability in vivo. A cross-sectional and longitudinal study of resonance frequency measurements on implants in the edentulous and partially dentate maxilla. Clin Oral Implants Res. 1997;8(3):226–33. Epub 1997/06/01. Meredith N, Alleyne D, Cawley P. Quantitative determination of the stability of the im...

References : Customized SmartPeg for measurement o...

Ersanli S, Karabuda C, Beck F, Leblebicioglu B. Resonance frequency analysis of one-stage dental implant stability during the osseointegration period. J Periodontol. 2005;76(7):1066–71. Epub 2005/07/16. Bornstein MM, Chappuis V, von Arx T, Buser D. Performance of dental implants after staged sinus floor elevation procedures: 5-year results of a prospective study in partially edentulous patients...

References : Customized SmartPeg for measurement o...

Shatkin TE, Oppenheimer BD, Oppenheimer AJ. Mini dental implants for long-term fixed and removable prosthetics: a retrospective analysis of 2514 implants placed over a five-year period. Compend Contin Educ Dent. 2007;28(2):92–9. quiz 100-1. Epub 2007/02/27. Griffitts TM, Collins CP, Collins PC. Mini dental implants: an adjunct for retention, stability, and comfort for the edentulous patient. Or...

References : Customized SmartPeg for measurement o...

Branemark PI, Adell R, Breine U, Hansson BO, Lindstrom J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3(2):81–100. Epub 1969/01/01. Meredith N. Assessment of implant stability as a prognostic determinant. Int J Prosthodont. 1998;11(5):491–501. Epub 1999/01/29. Lioubavina-Hack N, Lang NP, Karring T. Significance of primar...

Conclusions : Customized SmartPeg for measurement ...

The results of this animal study indicate that ISQ measurement of these single-piece MDIs is possible with the help of a custom-made SmartPeg and that 3M™ESPE™MDIs attain primary and secondary stability at the same levels as standard implants in the rabbit tibia.

Discussion : Customized SmartPeg for measurement o...

As there are no studies that provide data based on resonance frequency measurements for single-piece MDIs, the exact RFA threshold values for MDIs may have to be identified with more studies conducted in vivo. The resonance frequency assessment with a customized SmartPeg would be a useful tool to provide clinically useful information about the condition of the bone-implant interface of 3M™ ESPE...

Discussion : Customized SmartPeg for measurement o...

If the initial ISQ value is high, a small drop in stability normally levels out with time. A big drop in stability or decrease should be taken as a warning sign. Lower values are expected to be higher after the healing period. The opposite could be a sign of an unsuccessful implant, and actions should be taken accordingly. Studies have shown that the resonance frequency value is greatly associate...

Discussion : Customized SmartPeg for measurement o...

It is important to measure the Implant Stability Quotient (ISQ) of single-piece mini dental implants as they are becoming increasingly popular, with the concomitant increase in publications demonstrating their high survival and success rates. Although the clinical use of Osstell devices is also increasing, there is lack of studies on its use with single-piece implants, which do not have internal t...

Results : Customized SmartPeg for measurement of r...

The ISQ values obtained while calibrating the customized SmartPeg were similar to in vivo results. Median ISQ values at insertion and at 6 postoperative weeks were 53.3 (IQR 8.3) and 60.5 (5.5) for the 3M™ESPE™MDIs, and 58.5 (4.75) and 65.5 (9.3) for the Ankylos® implants, respectively, with no statistical difference (Figs. 2 and 3). The ISQ values of both 3M™ESPE™ MDI and Ankylos® (Fig...

Methods : Customized SmartPeg for measurement of r...

ISQ values were averaged and compared between implant types and times using Wilcoxon’s matched pairs signed-rank tests at a significance level of p 

Methods : Customized SmartPeg for measurement of r...

For the MDIs, a small longitudinal skin incision was made just distal to the tibia/femur joint. The tibia/femur head was exposed subperiosteally, and an osteotomy was performed with the pilot drill under copious irrigation with saline solution, transposing the cortical bone to the depth of 0.5 mm. The implants were aseptically transferred to the bone site and manually rotated clockwise while exer...

Methods : Customized SmartPeg for measurement of r...

Single use Osstell SmartPegs for standard implants are made from a soft metal with a zinc-coated magnet mounted on top of it and attached to the implants or abutments’ internal threads. As the company does not provide SmartPegs for one-piece implants, we developed a customized SmartPeg for mini dental implants (3M™ESPE™ MDIs), which do not have internal threads (Fig. 1). After confirming th...

Objective : Customized SmartPeg for measurement of...

The aim of the study is to test the feasibility of a customized SmartPeg for ISQ measurement of single-piece mini dental implants and to compare the primary stability of a standard and the mini dental implant (3M™ESPE™MDI) in a rabbit model after 6 weeks of healing.

Background : Customized SmartPeg for measurement o...

There are no published studies on the ISQ measurement of mini dental implants, as SmartPegs for these implants are not available till date. Since these are one-piece implants and do not have an internal thread for the SmartPeg’s attachment, a custom-made SmartPeg needs to be fabricated for ISQ measurement. Therefore, we developed and tested a customized SmartPeg for 3M™ESPE™ MDIs to measure ...

Background : Customized SmartPeg for measurement o...

Mechanical testing methods like reverse torque, or “pullout test,” have been used to study and measure the mechanical interface between implant and bone in various ways [22, 23]. The Branemark group has evaluated the mechanical properties of osseointegrated implants using torsion and pullout tests and lateral loading tests [24, 25]. Presence or absence of mobility and the bone level around the...

Background : Customized SmartPeg for measurement o...

Osseointegration refers to the phenomenon for close apposition of the bone to the surface of an implant with no interposing tissue that can be clinically demonstrated by absence of mobility [1, 2]. Obtaining primary stability seems to be a precondition for a successful osseointegration [3]. Dental implants have a success rate of over 90% and are available in various sizes with different surfaces [...

Abstract : Customized SmartPeg for measurement of ...

The new custom-made SmartPeg is suitable for measuring the Implant Stability Quotient of 3M™ESPE™MDIs. The primary stability of 3M™ESPE™MDIs is similar to the primary stability attained by standard implants in the rabbit tibia.

Abstract : Customized SmartPeg for measurement of ...

One-piece narrow diameter implants (NDIs) have been recommended as “Single-tooth replacements in the anterior zones, single posterior, multiple-unit fixed dental prosthesis (FDP), edentulous jaws to be rehabilitated with FDP, and edentulous jaws rehabilitation with overdentures in situations with reduced mesiodistal space or reduced ridge width.” (ITI consensus 2013). Since NDIs can be immedia...

Fig. 5. Periapical X ray after 1 year of follow-u...

Fig. 5. Periapical X ray after 1 year of follow-up, the bone was stable and no sign of peri-implantitis was shown Fig. 5. Periapical X ray after 1 year of follow-up, the bone was stable and no sign of peri-implantitis was shown

Fig. 4. Follow-up after 1 year, no radiographic s...

Fig. 4. Follow-up after 1 year, no radiographic sign was appreciating and the osseointegration was satisfactory Fig. 4. Follow-up after 1 year, no radiographic sign was appreciating and the osseointegration was satisfactory

Fig. 3. Final restaurations: The parallelism of th...

Fig. 3. Final restaurations: The parallelism of the implants is achieved by carving the non-submerged part a occlusal view and b lingual view Fig. 3. Final restaurations: The parallelism of the implants is achieved by carving the non-submerged part a occlusal view and b lingual view

Fig. 2. Flapless surgical technique, atraumatic su...

Fig. 2. Flapless surgical technique, atraumatic surgical procedure for zirconium implants using the circular scalpel (a)–sharp, clean cut without bleeding (b) Fig. 2. Flapless surgical technique, atraumatic surgical procedure for zirconium implants using the circular scalpel (a)–sharp, clean cut without bleeding (b)

Fig. 1. Diagnostic radiographic exploration previo...

Fig. 1. Diagnostic radiographic exploration previous to treatment Fig. 1. Diagnostic radiographic exploration previous to treatment

About this article : Zirconia implants and peek re...

Parmigiani-Izquierdo, J.M., Cabaña-Muñoz, M.E., Merino, J.J. et al. Zirconia implants and peek restorations for the replacement of upper molars. Int J Implant Dent 3, 5 (2017). https://doi.org/10.1186/s40729-016-0062-2 Download citation Received: 13 October 2016 Accepted: 22 December 2016 Published: 20 February 2017 DOI: https://doi.org/10.1186/s40729-016-0062-2

Rights and permissions : Zirconia implants and pee...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Zirconia implants and peek re...

Periodontics Unit, Faculty of Medicine and Dentistry, University of Murcia (Spain), Murcia, Spain Arturo Sánchez-Pérez Clínica CIROM, Murcia, 30001, Spain José María Parmigiani-Izquierdo, María Eugenia Cabaña-Muñoz & José Joaquín Merino Clínica Odontologíca Universitaria, Hospital Morales Meseguer, 2ª planta, C/ Marqués de los Vélez s/n, Murcia, 30008, Spain Arturo Sánchez-...

References : Zirconia implants and peek restoratio...

Download references

References : Zirconia implants and peek restoratio...

Bormann K-H, Gellrich N-C, Kniha H, Dard M, Wieland M, Gahlert M. Biomechanical evaluation of a microstructured zirconia implant by a removal torque comparison with a standard Ti-SLA implant. Clin oral implants res. 2012;23:1210–6. Oliva J, Oliva X, Oliva JD. One-year follow-up of first consecutive 100 zirconia dental implants in humans: a comparison of 2 different rough surfaces. Int j oral ma...

References : Zirconia implants and peek restoratio...

Brånemark PI, Hansson BO, Adell R, Breine U, Lindström J, Hallén O, et al. Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scand j plast reconstr surg suppl. 1977;16:1–132. Parmigiani-Izquierdo JM. TécnicaAtraumática en Implantología. Rev esp odontoestomatológica implant. 11:30–5. Parmigiani-Izquierdo JM, Sánchez-Pérez A, Cabaña-Mu...

Conclusions : Zirconia implants and peek restorati...

Zirconia implants with PEEK restorations can be considered a good alternative for replacing natural teeth. Their biocompatibility and biostability make them a promising material for those patients who suffer from allergies and sensitivity to metal alloys. PEEK restorations are a valid and alternative recommendation when using zirconia implants because of their cushioning effect and elastic modulu...

Case presentation : Zirconia implants and peek res...

In addition to PEEK, new coatings based on PMMA or composite materials (Anaxblent®Anaxdent®, Nexco®Ivoclar®, Solidex®Shofu®, Novo.lign®Bredent®, etc.) which incorporate ceramic fillings have been developed. Due to their molecular structure, these materials have excellent density and homogeneity [24]. The micro filling integrated into the polymer matrix increases abrasion resistance, at the...

Case presentation : Zirconia implants and peek res...

In terms of the load-cushioning capacity of the prosthetic elements, the use of PEEK as a prosthetic structure on implants has increased in recent years [14]. PEEK is a high-density thermoplastic polymer with a linear aromatic semi-crystalline structure that has exceptional physical and chemical properties as regards toughness, hardness and elasticity. Also, its low molecular weight, combined with...

Case presentation : Zirconia implants and peek res...

Fifteen days after surgery, the appearance of the soft tissue was excellent, with no signs of inflammation in the mucosa. The patient mentioned the absence of bleeding and pain during the post-operation period. At the same time, we made a clinical and radiological evaluation. Three months after surgery, the stumps of the implants were carved to improve their parallelism with a special diamond dril...

Case presentation : Zirconia implants and peek res...

A patient who is a 45-year-old woman and non-smoker has no medical record of interest. The patient complained of pain in the right second upper molar. She said that she felt intense pain while chewing. The pain was accentuated with occlusion and while chewing, making normal functioning impossible. The patient mentioned the absence of piece 16, which had been extracted 8 years previously. Clinica...

Background : Zirconia implants and peek restoratio...

In the field of implant dentistry, the most widely used implants over the past 40 years are those manufactured from titanium [1], which are still the most popular. The recent demands for materials without metal alloys in dentistry, together with the increased sensitivity and allergies of some patients, have promoted the development of new materials. An example of this is zirconia-based dental i...

Abstract : Zirconia implants and peek restorations...

One of the disadvantages of the zirconia implants is the lack of elasticity, which is increased with the use of ceramic or zirconia crowns. The consequences that could result from this lack of elasticity have led to the search for new materials with improved mechanical properties. A patient who is a 45-year-old woman, non-smoker and has no medical record of interest with a longitudinal fracture i...

Fig. 4. Comparative illustration of mean ISQ value...

Fig. 4. Comparative illustration of mean ISQ values Fig. 4. Comparative illustration of mean ISQ values

Fig. 3. Implants were placed after application of ...

Fig. 3. Implants were placed after application of CGF membrane Fig. 3. Implants were placed after application of CGF membrane

Fig. 2. CGF membrane was applied in study group im...

Fig. 2. CGF membrane was applied in study group implant sockets Fig. 2. CGF membrane was applied in study group implant sockets

Fig. 1. CGF was obtained after centrifugation : Ev...

Fig. 1. CGF was obtained after centrifugation Fig. 1. CGF was obtained after centrifugation

Table 3 Mean ISQ value changes between study and c...

  Control group Study group Immediate–1st week −2.25 ± 1.713 1.40 ± 1.847 Immediate–4th week −2.30 ± 2.774 0.60 ± 2.798 1st Week–4th week −0.05 ± 1.572 −0.80 ± 2.215   Table 3 Mean ISQ value changes between study and control groups

Table 2 Mean ISQ values in the study and control g...

  Control group Study group Immediate 75.75 ± 5.552 78.00 ± 2.828 1st week 73.50 ± 5.226 79.40 ± 2.604 4th week 73.45 ± 5.680 78.60 ± 3.136   Table 2 Mean ISQ values in the study and control groups

Table 1 Demographic data of patients : Evaluation ...

Case no. Age Sex Group Implant number 1 20 F Study 1 2 28 M Control 3 3 35 F Study 4 4 32 F Study 4 5 60 M Control 5 6 64 F Study 5 7 52 F Study 5 8 34 M Study 1 9 45 F Control 3 10 48 F Control 2 11 42 M Control 3 12 68 F Control 4   Table 1 Demographic data of patien...

About this article : Evaluation of effectiveness o...

Pirpir, C., Yilmaz, O., Candirli, C. et al. Evaluation of effectiveness of concentrated growth factor on osseointegration. Int J Implant Dent 3, 7 (2017). https://doi.org/10.1186/s40729-017-0069-3 Download citation Received: 16 December 2016 Accepted: 16 February 2017 Published: 03 March 2017 DOI: https://doi.org/10.1186/s40729-017-0069-3

Rights and permissions : Evaluation of effectivene...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Evaluation of effectiveness o...

Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Karadeniz Technical University, Trabzon, Turkey Cagasan Pirpir, Onur Yilmaz, Celal Candirli & Emre Balaban You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this a...

References : Evaluation of effectiveness of concen...

Prakash S, Thakur A. Platelet concentrates: past, present and future. J Maxillofac Oral Surg. 2011;10(1):45–9. Rodella LF, Favero G, Boninsegna R, Buffoli B, Labanca M, Scari G, et al. Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction. Microsc Res Tech. 2011;74(8):772–7. Ademokun JA, Chapman C, Dunn J, Lander D, Mair K, Proctor SJ, et al...

References : Evaluation of effectiveness of concen...

Huwiler MA, Pjetursson BE, Bosshardt DD, Salvi GE, Lang NP. Resonance frequency analysis in relation to jawbone characteristics and during early healing of implant installation. Clin Oral Implants Res. 2007;18(3):275–80. Kroese-Deutman HC, Vehof JW, Spauwen PH, Stoelinga PJ, Jansen JA. Orthotopic bone formation in titanium fiber mesh loaded with platelet-rich plasma and placed in segmental defe...

References : Evaluation of effectiveness of concen...

Nurden AT, Nurden P, Sanchez M, Andia I, Anitua E. Platelets and wound healing. Front Biosci. 2008;13:3532–48. Anitua E, Sanchez M, Zalduendo MM, de la Fuente M, Prado R, Orive G, et al. Fibroblastic response to treatment with different preparations rich in growth factors. Cell Prolif. 2009;42(2):162–70. He L, Lin Y, Hu X, Zhang Y, Wu H. A comparative study of platelet-rich fibrin (PRF) and ...

References : Evaluation of effectiveness of concen...

Raghavendra S, Wood MC, Taylor TD. Early wound healing around endosseous implants: a review of the literature. Int J Oral Maxillofac Implants. 2005;20(3):425–31. Oncu E, Bayram B, Kantarci A, Gulsever S, Alaaddinoglu EE. Positive effect of platelet rich fibrin on osseointegration. Med Oral Patol Oral Cir Bucal. 2016;21(5):e601–7. Anitua E. Plasma rich in growth factors: preliminary results o...

Abbreviations : Evaluation of effectiveness of con...

Bone morphogenetic protein Concentrated growth factor Computed tomography Insulin-like growth factor Platelet-derived growth factor Platelet-rich fibrin Platelet-rich plasma Resonance frequency analysis Transforming growth factor-β1 Transforming growth factor-β2 Vascular endothelial growth factor

Conclusions : Evaluation of effectiveness of conce...

Considering this data, it appears that application of CGF enhanced stability of implants and accelerated osseointegration in the early period. CGF has positive effects on the ISQ value at the first week and fourth week. Further laboratory studies are needed to demonstrate the positive effects of blood products on the osseointegration process at the histopathological level.

Discussion : Evaluation of effectiveness of concen...

In a study by Monov et al. using PRP around the implant, a higher stability value was obtained in the study group during the early recovery period (6 weeks) although difference between the groups was not statistically significant [23]. Kim et al. reported in a study that there was a statistically significant increase in bone-implant contact with PRP administration in the vicinity of the implant [...

Discussion : Evaluation of effectiveness of concen...

Introduced in 1998 by Marx, PRP is used in oral and maxillofacial surgeries to speed up the recovery of grafts in bone-grafted areas [14, 26–30]. Although many studies have shown that platelet-rich plasma affects bone healing positively, the results of some other studies suggest otherwise [31, 32]. In recent years, the platelet-rich fibrin (PRF) was described by Choukroun as a second-generation...

Discussion : Evaluation of effectiveness of concen...

Implant stability is one of the important parameters that assess the loading time and dental implant success. Investigators have recommended that implants with ISQ 

Results : Evaluation of effectiveness of concentra...

The study includes 12 patients (5 males, 7 females). Patients participating in the study are between 20–68 years of age and the mean age is 44 years. A total of 40 implants were placed, 20 of these were included in the study group (50%), and the other 20 were included in the control group (50%). Twenty-one implants were placed in type 2 bone, 19 implants in type 3 bone (Table 1). The distribu...

Methods : Evaluation of effectiveness of concentra...

Independent sample t test was applied between the two groups by taking the differences between the data obtained in these periods. Two-way ANOVA and Fisher’s LSD test was used for evaluating the associations among group and insertion torque. A value of p 

Methods : Evaluation of effectiveness of concentra...

All surgical procedures were performed under local anesthesia by the same surgeon. A full-thickness mucoperiosteal flap was removed by incision on the alveolar crest. Implant cavities were prepared according to the surgical protocol of the Bego Semados implant system (BEGO Implant Systems GmbH & Co. KG, Bremen, Germany). The final osteotomy diameters were the same as the placed implants. In the st...

Methods : Evaluation of effectiveness of concentra...

This study was conducted in compliance with the principles of the Declaration of Helsinki, and approval of the ethics committee required for the study was obtained from the Ethics Committee of the Karadeniz Technical University (2015/21). The procedures to be performed were explained in detail and patients signed the consent forms. The study was carried out on individuals who applied to Karadeniz ...

Background : Evaluation of effectiveness of concen...

That the implant has sufficient stability after placement is important for providing the necessary bone formation around the implant and for the optimal distribution of functional forces at the implant-bone interface during healing [15–17]. It can be said that resonance frequency analysis (RFA) is a very important tool for tracking the osseointegration process [18, 19]. RFA is a technique that ...

Background : Evaluation of effectiveness of concen...

Osseointegration of dental implants is important for long-term success and stability. There is no standardization in terms of the time of osseointegration and the timing of prosthetic loading. This process varies between 0–6 months [1]. Various strategies are being explored to shorten this period. Changes in implant surface properties and design have increased primer stability and helped the pe...

Abstract : Evaluation of effectiveness of concentr...

Growth factor-containing products have been reported to increase implant stability and accelerate osseointegration. Concentrated growth factor (CGF) can be used for this purpose with the growth factors it contains. The aim of this study is to assess the effect of CGF on implant stability and osseointegration. Twelve patients with maxillary anterior toothless were included in the study. Implant ca...

Fig. 3. Mean and standard deviation (SD) of percen...

Fig. 3. Mean and standard deviation (SD) of percentage of correct answers regarding hardness at each of the four times. The horizontal label axis was the time stage, and the label to the vertical axis was percentage of correct answers regarding hardness (%)

Fig. 2. a Mean and standard deviation (SD) of occl...

Fig. 2. label axis was the time stage (1) before implant surgery with the complete denture in situ and (2) right after with provisional implant, (3) 1–2 weeks and (4) 3 months after insertion of the provisional screw-retained restoration, and the label to the vertical axis was contact area (mm2). The occlusal contact area was increased at 3 months after wearing implants (paired t test, p 

Fig. 1. Correlation between measured Glucosensor v...

Fig. 1. Correlation between measured Glucosensor value (mg/dl) (the vertical axis) and applied glucose density (mg/dl) (the horizontal axis) in the in vitro setup. A linear regression line could be applied to the data set, and we tested the accuracy of Glucosensor value Fig. 1. Correlation between measured Glucosensor value (mg/dl) (the vertical axis) and applied glucose density (mg/dl) (the ...

About this article : Short-term follow-up of masti...

Tanaka, M., Bruno, C., Jacobs, R. et al. Short-term follow-up of masticatory adaptation after rehabilitation with an immediately loaded implant-supported prosthesis: a pilot assessment. Int J Implant Dent 3, 8 (2017). https://doi.org/10.1186/s40729-017-0070-x Download citation Received: 24 October 2016 Accepted: 23 February 2017 Published: 07 March 2017 DOI: https://doi.org/10.1186/s40729-017...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Short-term follow-up of masti...

Department of Prosthetic Dentistry, Graduate School of Biomedical Science, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan Mihoko Tanaka, Tetsurou Torisu & Hiroshi Murata Centre for Periodontology and Implantology Leuven, IJzerenmolenstraat 110, B-3001, Heverlee, Belgium Mihoko Tanaka & Collaert Bruno OMFS IMPATH, Department of Imaging & Pathology, University of Leuven, Kap...

Acknowledgements : Short-term follow-up of mastica...

The authors are grateful to the volunteers who participated in this study. This work was supported by JSPS Grant-in-Aid for Scientific Research (C), grant number 23592860. MT, CB, and RJ conceived and designed the experiment. MT and CB performed the experiments and analyzed the data with R J. TT and HM helped to draft the manuscript. All authors read and approved the final manuscript. Mihoko Tan...

References : Short-term follow-up of masticatory a...

Collaert B, Wijnen L, De Bruyn H. A 2-year prospective study on immediate loading with fluoride-modified implants in the edentulous mandible. Clin Oral Implants Res. 2011;22:1111–6. Collaert B, De Bruyn H. Immediate functional loading of TiOblast dental implants in full-arch edentulous maxillae: a 3-year prospective study. Clin Oral Implants Res. 2008;19:1254–60. Matsui Y, Ohno K, Michi K, S...

References : Short-term follow-up of masticatory a...

Bakke M, Holm B, Gotfredsen K. Masticatory function and patient satisfaction with implant-supported mandibular overdentures: a prospective 5-year study. Int J Prosthodont. 2002;15:575–81. Miyaura K, Morita M, Matsuka Y, Yamashita A, Watanabe T. Rehabilitation of biting abilities in patients with different types of dental prostheses. J Oral Rehabil. 2000;27:1073–6. Peyron MA, Blanc O, Lund JP...

References : Short-term follow-up of masticatory a...

Trulsson M, Johansson RS. Encoding of amplitude and rate of forces applied to the teeth by human periodontal mechanoreceptive afferents. J Neurophysiol. 1994;72:1734–44. Hidaka O, Morimoto T, Masuda Y, Kato T, Matsuo R, Inoue T, et al. Regulation of masticatory force during cortically induced rhythmic jaw movements in the anesthetized rabbit. J Neurophysiol. 1997;77:3168–79. Hidaka O, Morimo...

References : Short-term follow-up of masticatory a...

Klineberg IJ, Trulsson M, Murray GM. Occlusion on implants—is there a problem? J Oral Rehabil. 2012;39:522–37. Feine J, Jacobs R, Lobbezoo F, Sessle BJ, Van Steenberghe D, Trulsson M, Fejerskov O, Svensson P. A functional perspective on oral implants—state-of-the-science and future recommendations. J Oral Rehabil. 2006;33:309–12. Jacobs R, van Steenberghe D, Naert I. Masseter muscle fati...

Conclusions : Short-term follow-up of masticatory ...

The present pilot study could not confirm an immediate rise in bite force after implant rehabilitation. Instead, improvements were mainly noted up to 3 months after surgery and rehabilitation. Furthermore, it became evident that despite gradually improved bite force in all patients, masticatory efficiency and food hardness perception did not necessarily follow the same trend. The present findings...

Discussion : Short-term follow-up of masticatory a...

Occlusal contact was significantly increased 3 months after implant rehabilitation when compared to stage one (prior to implant rehabilitation). We assumed the reason was that some participant’s occlusion was worn down because the material of provisional restoration was resin. To observe the adaptation of masticatory function after rehabilitation with an immediately loaded implant-supported pro...

Results : Short-term follow-up of masticatory adap...

Hardness perception became better after implant rehabilitation, with a reduction of the error rate by 16% (Fig. 3). While five out of eight participants performed better in this test after rehabilitation, the results in the others were less clear. More detailed analysis showed that, despite wearing dentures, four participants were 100% successful in recognition of hardness before implant surgery,...

Results : Short-term follow-up of masticatory adap...

Two participants were unavailable to attend the testing at 1–2 weeks after the provisional restoration had been inserted, which resulted in missing data. Overall descriptive analyses yielded the following observations for the four tests. Occlusal contact and approximate maximum bite force were significantly increased 3 months after implant rehabilitation because of the adjustment of provisio...

Methods : Short-term follow-up of masticatory adap...

To assess the hardness differences, the examiner placed each test specimen on the tongue with chopsticks, and then the participants chewed on all sides and swallowed. They were asked to remember the hardness of the first specimen, which always had medium hardness and served as a control, and then to determine the level of hardness (hard, medium, or soft) of four consecutive and randomly administer...

Methods : Short-term follow-up of masticatory adap...

To assess the masticatory efficiency, we used glucose extraction in the filtrate obtained after chewing the specimen. After rinsing the mouth with tap water, a gum-like specimen mixed with 5% glucose with a height of 10 mm (Glucosensor Gummy, GC, Tokyo, Japan) was placed on patient’s tongue with chopsticks. Patients were requested to chew on the cube for 20 s, after which, they expectorated al...

Methods : Short-term follow-up of masticatory adap...

Six females and 2 males (average age 66.4 years, range 52–85 years) with upper (n = 7) or lower (n = 1) complete dentures participated in this study. Inclusion criteria were (1) an opposite jaw that included natural dentition at least to the second premolar on both sides, (2) a need for fixed rehabilitation, (3) no medical contraindication to the placement of implants, (4) no need for ...

Background : Short-term follow-up of masticatory a...

The purpose of this pilot investigation was to use testing methodologies involving four aspects of masticatory adaptation after rehabilitation with an immediately loaded implant-supported prosthesis and to observe the recovery of each aspect respectively. Our hypothesis is that bite force may recover quickly, but other aspects will require monitoring and recording in order to form an overall judgm...

Background : Short-term follow-up of masticatory a...

In addition, it also remains to be demonstrated how a potential compensatory mechanism might work, with one of the options being osseoperception [2, 18–23]. In this context, it is also important to consider the adaptation time needed after oral rehabilitation. Some studies have performed longitudinal evaluations of masticatory function for more than 3 years [24, 25]. However, there are limited ...

Background : Short-term follow-up of masticatory a...

Tooth loss represents a major oral disability comparable to an amputation, with severe impairment of oral functions [1]. While denture wearers can rely on mucosal sensors, anchoring prosthetic teeth to the bone via osseointegrated implants has been assumed to create a (partial) sensory substitution for missing periodontal ligament receptors from stimuli transmitted via the bone [2]. The restoratio...

Abstract : Short-term follow-up of masticatory ada...

When teeth are extracted, sensory function is decreased by a loss of periodontal ligament receptions. When replacing teeth by oral implants, one hopes to restore the sensory feedback pathway as such to allow for physiological implant integration and optimized oral function with implant-supported prostheses. What remains to be investigated is how to adapt to different oral rehabilitations. The pur...

Fig. 12. Facial photograph views at 22-month follo...

Fig. 12. Facial photograph views at 22-month follow-up Fig. 12. Facial photograph views at 22-month follow-up

Fig. 11. Facial radiograph at 22-month follow-up :...

Fig. 11. Facial radiograph at 22-month follow-up Fig. 11. Facial radiograph at 22-month follow-up

Fig. 10. Full facial view of definitive implant-re...

Fig. 10. Full facial view of definitive implant-retained obturator at initial fitting (April 2014) Fig. 10. Full facial view of definitive implant-retained obturator at initial fitting (April 2014)

Fig. 9. Palatal view of definitive implant-retaine...

Fig. 9. Palatal view of definitive implant-retained obturator at initial fitting (April 2014) Fig. 9. Palatal view of definitive implant-retained obturator at initial fitting (April 2014)

Fig. 8. Anterior view of definitive obturator pros...

Fig. 8. Anterior view of definitive obturator prosthesis in occlusion Fig. 8. Anterior view of definitive obturator prosthesis in occlusion

Fig. 7. Smile view of definitive implant-retained ...

Fig. 7. Smile view of definitive implant-retained obturator at initial fitting (April 2014) Fig. 7. Smile view of definitive implant-retained obturator at initial fitting (April 2014)

Fig. 6. Intaglio surface of definitive acrylic obt...

Fig. 6. Intaglio surface of definitive acrylic obturator with bar attachments in place. Note the absence of any other retaining clasps and the simple nature of this prosthesis Fig. 6. Intaglio surface of definitive acrylic obturator with bar attachments in place. Note the absence of any other retaining clasps and the simple nature of this prosthesis

Fig. 5. Zygomatic implant bar utilising Rhein atta...

Fig. 5. Zygomatic implant bar utilising Rhein attachments for retention Fig. 5. Zygomatic implant bar utilising Rhein attachments for retention

Fig. 4. Twelve-week review post-surgery prior to d...

Fig. 4. Twelve-week review post-surgery prior to definitive impressions for the implant-supported prosthesis Fig. 4. Twelve-week review post-surgery prior to definitive impressions for the implant-supported prosthesis

Fig. 3. Low-level right-sided maxillectomy with th...

Fig. 3. Low-level right-sided maxillectomy with the insertion of two zygomatic oncology implants at time of surgery Fig. 3. Low-level right-sided maxillectomy with the insertion of two zygomatic oncology implants at time of surgery

Fig. 2. Palatal swelling (post-biopsy) between upp...

Fig. 2. Palatal swelling (post-biopsy) between upper right first and second premolar teeth Fig. 2. Palatal swelling (post-biopsy) between upper right first and second premolar teeth

Fig. 1. Zygomatic oncology implant with cleansable...

Fig. 1. Zygomatic oncology implant with cleansable polished surface for intra-oral component Fig. 1. Zygomatic oncology implant with cleansable polished surface for intra-oral component

About this article : A novel report on the use of ...

Dattani, A., Richardson, D. & Butterworth, C.J. A novel report on the use of an oncology zygomatic implant-retained maxillary obturator in a paediatric patient. Int J Implant Dent 3, 9 (2017). https://doi.org/10.1186/s40729-017-0073-7 Download citation Received: 24 November 2016 Accepted: 26 February 2017 Published: 28 March 2017 DOI: https://doi.org/10.1186/s40729-017-0073-7

Rights and permissions : A novel report on the use...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : A novel report on the use of ...

Oral and Maxillofacial Surgery, Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, UK Amit Dattani Maxillofacial Surgery, Regional Craniofacial Unit, Alder Hey Children’s Hospital, Liverpool, UK David Richardson Maxillofacial Prosthodontics, Regional Maxillofacial Unit, University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL, UK Chris J. Butterworth You can also sea...

References : A novel report on the use of an oncol...

Brown JS, Shaw RJ. Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol. 2010;11(10):1001–8. Breeze J, Rennie A, Morrison A, Dawson D, Tipper J, Rehman K, et al. Health-related quality of life after maxillectomy: obturator rehabilitation compared with flap reconstruction. Br J Oral Maxillofac Surg. 2016;54(8):857–62. Kim SM, Park MW, Cho YA, Myoung H, Lee...

Conclusions : A novel report on the use of an onco...

The use of zygomatic implants to supplement the stability and retention of the maxillary obturator in this case has improved the function of the prosthesis and provided for a very high-quality rehabilitation for the patient reported with no evidence of disruption to facial growth in the 22 months following surgery.

Discussion : A novel report on the use of an oncol...

The use of modified zygomatic implants (Fig. 1) allows improved hygiene by the patient of the implants within the maxillary defect. The threaded portion of the implants is fully engaged into the bone with only the smooth portion protruding into the defect. Clearly this ongoing hygiene by the patient is of utmost importance in preventing peri-implant soft and hard tissue changes, but the implant d...

Discussion : A novel report on the use of an oncol...

The difficulty of restoration with a maxillary obturator prosthesis depends on the extent of the surgical resection, with the acceptance that resections with an increasing horizontal component provide a much greater prosthodontic challenge. The number of remaining teeth is a key component in conventional obturator design [9] with the remaining dentition being used exclusively to retain the prosthe...

Discussion : A novel report on the use of an oncol...

The paediatric population rarely suffer malignant disease of the oral cavity requiring any form of maxillectomy, and there is little published evidence around the rehabilitation and restorative management of children undergoing such procedures. The seemingly most common approach for a limited low-level maxillary resection in a child would be to consider resection and simple prosthetic obturation a...

Case presentation : A novel report on the use of a...

Four weeks later, the patient was returned to the operating room for removal and modification of the obturator. The cavity was healing well, and both implants were firm with no evidence of infection. The initial obturator was modified with the application of a soft lining material and the patient subsequently discharged with instructions on the insertion and removal of the obturator. At the 12-we...

Case presentation : A novel report on the use of a...

A medically fit and well 13-year 11-month-old male was referred to the oral and maxillofacial surgery department at Alder Hey Children’s Hospital in Liverpool in regard to an intra-oral swelling of the right palatal region (Fig. 2). An incisional biopsy was initially reported as a pleomorphic adenoma of the premolar region. Subsequently, a CT scan showed no significant bony abnormality, and a w...

Background : A novel report on the use of an oncol...

The characteristics of a good obturator will improve swallowing, speech function, minimise nasal fluid leakage from the antrum and nasal spaces, restore facial aesthetics including the teeth and facilitate masticatory function and speech. A surgical obturator can be provided at the time of surgery to facilitate function and haemostasis in the immediate post-operative period, and this can subsequen...

Background : A novel report on the use of an oncol...

Maxillary defects of acquired [1] or congenital origin produce a communication between the oral and nasal cavities sometimes via an opening into the maxillary antrum and by direct communication into the nose. This in turn can result in masticatory compromise, swallowing and speech impairment, nasal fluid regurgitation and aesthetic concerns. The management of the maxillectomy patient is a complex ...

Abstract : A novel report on the use of an oncolog...

This report details the use of zygomatic oncology osseointegrated implants to support and retain a maxillary obturator in a 13-year-old male patient who underwent a right-sided hemi-maxillectomy (Brown Class 2b) (Brown and Shaw, Lancet Oncol 11:1001–8, 2010) for a myxoid spindle cell carcinoma. At the time of maxillary resection, two zygomatic oncology implants were inserted into the right zygom...

Fig. 5. Total score for physical and psychological...

Fig. 5. Total score for physical and psychological disabilities before (gray) and after (hatched) sinus augmentation according to indications Fig. 5. Total score for physical and psychological disabilities before (gray) and after (hatched) sinus augmentation according to indications

Fig. 4. Total score for functional limitations bef...

Fig. 4. Total score for functional limitations before (gray) and after (hatched) sinus augmentation according to indications Fig. 4. Total score for functional limitations before (gray) and after (hatched) sinus augmentation according to indications

Fig. 3. Total score for complaints due to surgical...

Fig. 3. Total score for complaints due to surgical procedure pre-operative, post-operative, and recently Fig. 3. Total score for complaints due to surgical procedure pre-operative, post-operative, and recently

Fig. 2. Cumulative survival rate according to Kapl...

Fig. 2. Cumulative survival rate according to Kaplan–Meier and sinus augmentation procedure Fig. 2. Cumulative survival rate according to Kaplan–Meier and sinus augmentation procedure

Fig. 1. Flow chart of patients included in the stu...

Fig. 1. Flow chart of patients included in the study Fig. 1. Flow chart of patients included in the study

Table 3 Mean value and standard deviation for the ...

Item Mean ± SD pre-operative Mean ± SD post-operative Mean ± SD in the last time Have you felt pain in your mouth? ...

Table 2 Mean value and standard deviation for the ...

Item Mean ± SD before sinus lift Mean ± SD after sinus lift p value Have you felt tense because of problems with your teeth, mouth or dentures? ...

Table 1 Mean value and standard deviation for the ...

Item Mean ± SD before sinus lift Mean ± SD after sinus lift p value Have you had difficulty chewing any foods? ...

About this article : Impact of maxillary sinus aug...

Schiegnitz, E., Kämmerer, P.W., Sagheb, K. et al. Impact of maxillary sinus augmentation on oral health-related quality of life. Int J Implant Dent 3, 10 (2017). https://doi.org/10.1186/s40729-017-0072-8 Download citation Received: 20 November 2016 Accepted: 12 March 2017 Published: 28 March 2017 DOI: https://doi.org/10.1186/s40729-017-0072-8

Rights and permissions : Impact of maxillary sinus...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Impact of maxillary sinus aug...

Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Centre of the Johannes Gutenberg-University, Augustusplatz 2, 55131, Mainz, Germany E. Schiegnitz, K. Sagheb, A. Pabst, B. Al-Nawas & M. O. Klein Department of Oral and Maxillofacial Surgery, Plastic Surgery, University of Rostock, Rostock, Germany P. W. Kämmerer Department of Prosthodontics, University of ...

References : Impact of maxillary sinus augmentatio...

Stellingsma K, Bouma J, Stegenga B, Meijer HJ, Raghoebar GM. Satisfaction and psychosocial aspects of patients with an extremely resorbed mandible treated with implant-retained overdentures. A prospective, comparative study. Clin Oral Implants Res. 2003;14(2):166–72. Heydecke G, Locker D, Awad MA, Lund JP, Feine JS. Oral and general health-related quality of life with conventional and implant d...

References : Impact of maxillary sinus augmentatio...

Locker D. Self-esteem and socioeconomic disparities in self-perceived oral health. J Public Health Dent. 2009 Winter;69(1):1-8. Allen PF, McMillan AS, Walshaw D. A patient-based assessment of implant-stabilized and conventional complete dentures. J Prosthet Dent. 2001;85(2):141–7. Ohrn K, Jonsson B. A comparison of two questionnaires measuring oral health-related quality of life before and aft...

References : Impact of maxillary sinus augmentatio...

Al-Nawas B, Schiegnitz E. Augmentation procedures using bone substitute materials or autogenous bone—a systematic review and meta-analysis. Eur J Oral Implantol. 2014 Summer;7 Suppl 2:S219-34. Derks J, Hakansson J, Wennstrom JL, Tomasi C, Larsson M, Berglundh T. Effectiveness of implant therapy analyzed in a Swedish population: early and late implant loss. J Dent Res. 2015;94(3 Suppl):44S–51S...

Conclusions : Impact of maxillary sinus augmentati...

Within the limitations of this study, the results demonstrated a high long-term survival for sinus augmentation procedures and significant improvement of OHRQoL after this procedure. Therefore, sinus augmentation procedures are highly valuable treatment options in implant dentistry.

Discussion : Impact of maxillary sinus augmentatio...

In order to measure OHRQoL in the present study, a specific and shortened questionnaire based on the validated and reliable OHIP score was developed to consider representative impairments of maxillary sinus augmentation like sinusitis and to relieve the clinical application. In a cross sectional study, Allen et McMillan proofed that a shortened OHIP-14 version showed a similar ability to assess OH...

Discussion : Impact of maxillary sinus augmentatio...

The clinical and radiological outcomes of sinus augmentation procedures have been published in several studies [1, 3, 6, 7]. However, little data on the physical and psychological impact of this procedure on the patient is available yet. The present study evaluated pre-operative and post-treatment OHRQoL self-assessment scores of patients treated with dental implants after sinus augmentation proce...

Results : Impact of maxillary sinus augmentation o...

Concerning functional limitations, all posed questions showed significant better values for OHRQoL after sinus augmentation procedure than before the treatment (p 

Results : Impact of maxillary sinus augmentation o...

After an average time in situ of 41.2 ± 27 months (3.4 years; range 0–96 months), 40 of the 863 implants were lost. These results indicated an in situ rate of 95.4%. One-year and five-year survival rate according to Kaplan–Meier were 95.4 and 94.4%. In patients receiving an external sinus lift an in situ rate of 95.1% and in patients with an internal sinus lift an in situ rate of 96.4%...

Methods : Impact of maxillary sinus augmentation o...

The Kaplan–Meier survival function was applied for the description of survival rates. To examine the statistical difference between survival rates, a log-rank test was used. Implant-related data were calculated. For statistical comparison of the paired questions and the total scores, a Wilcoxon test was applied. The intention of this study was descriptive, exploratory without a primary hypothesi...

Methods : Impact of maxillary sinus augmentation o...

This retrospective study addresses the oral health-related quality of life after maxillary sinus augmentation. Therefore, all patients that received an implantation after maxillary sinus augmentation in the Department of Oral and Maxillofacial Surgery of the University Medical Centre Mainz, Germany, between July 2002 and December 2007 were included in this study. There were no specific exclusion c...

Background : Impact of maxillary sinus augmentatio...

In conclusion, little information is available about patient’s perception of sinus augmentation procedures. The aim of the present study was to assess whether sinus augmentation procedures together with implant placement and prosthetic rehabilitation improve quality of life in dental patients using a modified German OHIP and to examine the survival rates after this procedure.

Background : Impact of maxillary sinus augmentatio...

Rehabilitation of completely and partial edentulous patients with dental implants has proved to be a safe and predictable procedure [1–3]. However, reduced bone height and the proximity of the maxillary sinus are challenging limitations for dental implant placement in the posterior maxilla [3]. Besides the use of short and tilted implants [4], one of the most frequently used surgical techniques ...

Abstract : Impact of maxillary sinus augmentation ...

The aim of this study was to measure the oral health-related quality of life (OHRQoL) after maxillary sinus augmentation to determine the physical and psychological impact of this procedure for the patient. Three hundred sixteen patients treated with an external or internal maxillary sinus augmentation and a total of 863 implants in the Department of Oral and Maxillofacial Surgery, Johannes Guten...

Fig. 6. a Panoramic radiograph 16 months after th...

Fig. 6. a Panoramic radiograph 16 months after the sequestrectomy. b Sagittal CT view. c Coronal CT view. d 3D CT view

Fig. 5. a Extraoral photograph 5 months after the...

Fig. 5. tograph 5 months after the sequestrectomy. Fig. 5. a Extraoral photograph 5 months after the sequestrectomy. b Intraoral photograph 5 months after the sequestrectomy.

Fig. 4. a Preoperative intraoral photograph. b Int...

Fig. 4. y. c Removal of the dental implant with a specimen of the necrotic bone Fig. 4. a Preoperative intraoral photograph. b Intraoperative photograph of the sequestrectomy. c Removal of the dental implant with a specimen of the necrotic bone

Fig. 3. a Panoramic radiograph showing the sequest...

Fig. 3. Fig. 3. a Panoramic radiograph showing the sequestrum separation after 5 months of teriparatide therapy (arrows). b Sagittal CT view. c Coronal CT view

Fig. 2. a Panoramic radiograph showing marked alve...

molar (arrow). b Sagittal CT view. c Coronal CT view Fig. 2. a Panoramic radiograph showing marked alveolar bone resorption surrounding the dental implant replacing the right mandibular first molar (arrow). b Sagittal CT view. c Coronal CT view

Fig. 1. a Extraoral photograph showing an extraora...

Fig. 1. al implants associated with mucosal inflammation and a purulent discharge Fig. 1. a Extraoral photograph showing an extraoral fistula in the right mandibular region. b Intraoral photograph showing an intraoral fistula on the lingual side of the distal dental implants associated with mucosal inflammation and a purulent discharge

About this article : Treatment with teriparatide f...

Zushi, Y., Takaoka, K., Tamaoka, J. et al. Treatment with teriparatide for advanced bisphosphonate-related osteonecrosis of the jaw around dental implants: a case report. Int J Implant Dent 3, 11 (2017). https://doi.org/10.1186/s40729-017-0074-6 Download citation Received: 06 December 2016 Accepted: 12 February 2017 Published: 30 March 2017 DOI: https://doi.org/10.1186/s40729-017-0074-6

Rights and permissions : Treatment with teriparati...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Treatment with teriparatide f...

Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan Yusuke Zushi, Kazuki Takaoka, Joji Tamaoka, Miho Ueta, Kazuma Noguchi & Hiromitsu Kishimoto You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed ...

References : Treatment with teriparatide for advan...

Stanton DC, Balasanian E. Outcome of surgical management of bisphosphonate-related osteonecrosis of the jaws: review of 33 surgical cases. J Oral Maxillofac Surg. 2009;67:943–50. Carlson ER, Basile JD. The role of surgical resection in the management of bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2009;67:85–95. Wilde F, Heufelder M, Winter K, et al. The role of ...

References : Treatment with teriparatide for advan...

Grant BT, Amenedo C, Freeman K, Kraut RA. Outcomes of placing dental implants in patients taking oral bisphosphonates: a review of 115 cases. J Oral Maxillofac Surg. 2008;66:223–30. Goss A, Bartold M, Sambrook P, Hawker P. The nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in dental implant patients: a South Australian case series. J Oral Maxillofac Surg. 2010;68:33...

References : Treatment with teriparatide for advan...

Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003;61:1115–7. Marx RE, Sawatari J, Fortin M, et al. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws; risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg. 2005;63:1567. Harper RP, Fung E. Resolution of...

Conclusions : Treatment with teriparatide for adva...

We have reported a case of a severely osteoporotic elderly woman with BRONJ around her dental implants, who was treated successfully with teriparatide. Teriparatide therapy appeared to exert beneficial effects in this patient.

Discussion : Treatment with teriparatide for advan...

It is therefore important that all patients treated with oral BPs must be given a full explanation of the potential risks of implant failure and BRONJ development in the short and long term. Because the potential role of infection in implant failure and BRONJ occurrence is still debated, great attention should be paid to the long-term oral hygiene and plaque control of implant-prosthetic restorati...

Discussion : Treatment with teriparatide for advan...

We describe a case of a patient with a 6-year history of alendronate therapy, in which BRONJ developed around her dental implants. In this patient, the dental implants achieved successful osseointegration, and BRONJ occurred after the second surgery. Several factors could have played a role in the development of BRONJ in this patient. Glucocorticoid therapy is associated with an increased risk of ...

Case presentation : Treatment with teriparatide fo...

In November 2011, after a consultation with an osteoporosis expert at the Orthopedic Medicine Clinic of our hospital, alendronate therapy was stopped and subcutaneous teriparatide therapy at a dose of 20 μg per day was started. During the course of the teriparatide therapy, the patient continued to use 0.02% benzalkonium chloride solution for local irrigation. In April 2012, after 5 months of ...

Case presentation : Treatment with teriparatide fo...

A 66-year-old woman was referred to the Oral and Maxillofacial Surgery Clinic at Hyogo College of Medicine Hospital, Japan, in September 2011, for an extraoral fistula and refractory pain of the right mandible associated with a purulent discharge and soft tissue swelling. The patient’s osteoporosis was diagnosed in 2005 and treated with 35 mg of alendronate weekly by the family doctor. The pati...

Background : Treatment with teriparatide for advan...

Oral bisphosphonates (BPs) are used to treat osteoporosis, Paget’s disease, and osteogenesis imperfecta. They are most widely used for treatment of osteoporosis. BP-related osteonecrosis of the jaw (BRONJ) was first reported by Marx in 2003 [1]. The risk of BRONJ in osteoporotic patients treated with BPs remains low compared with that of oncology patients [2]. Recent studies have indicated that ...

Abstract : Treatment with teriparatide for advance...

We report a case of a 66-year-old severely osteoporotic woman with bisphosphonate-related osteonecrosis of the jaw (BRONJ) around her dental implants, who was treated successfully with teriparatide and sequestrectomy of the mandible. After 5 months of teriparatide therapy, the sequestrum separation had progressed and a sequestrectomy was performed under general anesthesia. Five months after the o...

Fig. 6. Micro CT scan images of the MDIs and Ankyl...

Fig. 6. Micro CT scan images of the MDIs and Ankylos® embedded in rabbit bone 6 weeks post implantation Fig. 6. Micro CT scan images of the MDIs and Ankylos® embedded in rabbit bone 6 weeks post implantation

Fig. 5. Histological section of standard implant i...

Fig. 5. Histological section of standard implant in rabbit tibia stained with methylene blue and basic fuchsin Fig. 5. Histological section of standard implant in rabbit tibia stained with methylene blue and basic fuchsin

Fig. 4. Histological section of mini dental implan...

Fig. 4. Histological section of mini dental implant in rabbit tibia stained with methylene blue and basic fuchsin Fig. 4. Histological section of mini dental implant in rabbit tibia stained with methylene blue and basic fuchsin

Fig. 3. Histological sections being obtained with ...

Fig. 3. Histological sections being obtained with Leica SP 1600 saw microtome Fig. 3. Histological sections being obtained with Leica SP 1600 saw microtome

Fig. 2. Leica SP 1600 saw microtome : Osseointegra...

Fig. 2. Leica SP 1600 saw microtome Fig. 2. Leica SP 1600 saw microtome

Fig. 1. Radiograph showing implants in the rabbit ...

Fig. 1. Radiograph showing implants in the rabbit tibia Fig. 1. Radiograph showing implants in the rabbit tibia

Table 2 Descriptive statistics of the experimental...

BIC 3M™ ESPE™ MDIs Ankylos® Friadent (Dentsply) Median 58.5 57 Mean 57 56.5 Interquartile range 8 5.5 First quartile 53.25 53.75 Third quartile 61.25 59.25   Table 2 Descriptive statistics of the experimental and control group

Table 1 Comparison of % BIC in both groups : Osseo...

Sample 3M™ESPE™ MDIs Ankylos® 1. 67 54 2. 59 67 3. 54 45 4. 51 58 5. 47 57 6. 64 49 7. 50 54 8. 60 56 9. 56 60 10. 61 53 11. 62 59 12. 61 55 13. 59 59 14. 45 51 15. 58 59 16. 54 62 17. 66 62 18. 56 57   Table 1 Comparison of % BIC in both groups

About this article : Osseointegration of standard ...

Dhaliwal, J.S., Albuquerque, R.F., Murshed, M. et al. Osseointegration of standard and mini dental implants: a histomorphometric comparison. Int J Implant Dent 3, 15 (2017). https://doi.org/10.1186/s40729-017-0079-1 Download citation Received: 22 February 2017 Accepted: 26 April 2017 Published: 01 May 2017 DOI: https://doi.org/10.1186/s40729-017-0079-1

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional information : Osseointegration of stand...

This article was ammended to correct discrpencies in the Abstract. An erratum has also been published for this manuscript. An erratum to this article is available at http://dx.doi.org/10.1186/s40729-017-0088-0.

Author information : Osseointegration of standard ...

Faculty of Dentistry, McGill University, 2001 McGill College Avenue, Suite 500, Montreal, Quebec, H3A 1G1, Canada Jagjit S. Dhaliwal, Monzur Murshed & Jocelyne S. Feine Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil Rubens F. Albuquerque Jr Department of Medicine, McGill University, Montreal, Quebec, Canada Monzur Murshed You can also search...

References : Osseointegration of standard and mini...

Schwartz Z, Lohmann CH, Oefinger J, Bonewald LF, Dean DD, Boyan BD. Implant surface characteristics modulate differentiation behavior of cells in the osteoblastic lineage. Adv Dent Res. 1999;13:38–48. Boyan BD, Lossdorfer S, Wang L, Zhao G, Lohmann CH, Cochran DL, et al. Osteoblasts generate an osteogenic microenvironment when grown on surfaces with rough microtopographies. Eur Cell Mater. 2003...

References : Osseointegration of standard and mini...

Hayakawa T, Yoshinari M, Kiba H, Yamamoto H, Nemoto K, Jansen JA. Trabecular bone response to surface roughened and calcium phosphate (Ca-P) coated titanium implants. Biomaterials. 2002;23(4):1025–31. Sul YT, Byon ES, Jeong Y. Biomechanical measurements of calcium-incorporated oxidized implants in rabbit bone: effect of calcium surface chemistry of a novel implant. Clin Implant Dent Relat Res. ...

References : Osseointegration of standard and mini...

Park JW, Kim HK, Kim YJ, An CH, Hanawa T. Enhanced osteoconductivity of micro-structured titanium implants (XiVE S CELLplus) by addition of surface calcium chemistry: a histomorphometric study in the rabbit femur. Clin Oral Implants Res. 2009;20(7):684–90. Yang GL, He FM, Yang XF, Wang XX, Zhao SF. Bone responses to titanium implants surface-roughened by sandblasted and double etched treatments...

References : Osseointegration of standard and mini...

Buser D, Schenk RK, Steinemann S, Fiorellini JP, Fox CH, Stich H. Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs. J Biomed Mater Res. 1991;25(7):889–902. Gotfredsen K, Wennerberg A, Johansson C, Skovgaard LT, Hjorting-Hansen E. Anchorage of TiO2-blasted, HA-coated, and machined implants: an experimental study with rabbi...

References : Osseointegration of standard and mini...

Trisi P, Lazzara R, Rao W, Rebaudi A. Bone-implant contact and bone quality: evaluation of expected and actual bone contact on machined and osseotite implant surfaces. Int J Periodontics Restorative Dent. 2002;22(6):535–45. Froum SJ, Simon H, Cho SC, Elian N, Rohrer MD, Tarnow DP. Histologic evaluation of bone-implant contact of immediately loaded transitional implants after 6 to 27 months. In...

References : Osseointegration of standard and mini...

Hong RK, Heo JM, Ha YK. Lever-arm and mini-implant system for anterior torque control during retraction in lingual orthodontic treatment. Angle Orthod. 2005;75(1):129–41. Mazor Z, Steigmann M, Leshem R, Peleg M. Mini-implants to reconstruct missing teeth in severe ridge deficiency and small interdental space: a 5-year case series. Implant Dent. 2004;13(4):336–41. Siddiqui AA, Sosovicka M, Go...

References : Osseointegration of standard and mini...

Branemark PI, Adell R, Breine U, Hansson BO, Lindstrom J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3(2):81–100. Boerrigter EM, Stegenga B, Raghoebar GM, Boering G. Patient satisfaction and chewing ability with implant-retained mandibular overdentures: a comparison with new complete dentures with or without preprosthetic ...

Conclusions : Osseointegration of standard and min...

The results of this study show that MDIs as well as regular implants osseointegrate in rabbits.

Discussion : Osseointegration of standard and mini...

Our study is also in concordance with the results of a removal torque study by Simon et al. [63] in immediately loaded “transitional endosseous implants” in humans. The percentage BIC for MDIs was similar to standard implants. The surface topography also affects the BIC, Wennerberg et al. [32] measured and compared removal torque values on screw-shaped titanium implants with three surface typ...

Discussion : Osseointegration of standard and mini...

The osseointegration potential of 3M™ESPE™ MDIs has not been studied. The MDI is a one-piece implant that simplifies the restorative phase resulting in a reduced cost for the patient. Titanium-aluminum-vanadium alloy (Ti 6Al-4V-ELI) is used for increased strength. The success of these implants led to its use in long-term fixed and removable dental prostheses [51]. Conventional implant treatmen...

Results : Osseointegration of standard and mini de...

On the whole, postoperative wound healing in all the rabbits was good. None of them exhibited any signs of wound infection or exposure. A total of 36 specimens were retrieved for histological examination. All of the implants in both groups showed osseointegration and displayed a good amount of bone contact length (Figs. 4 and 5). No discernible differences were noticed between both the groups. T...

Methods : Osseointegration of standard and mini de...

The saw blade has a thickness of 280 μm and a feed of 310 μm was selected to obtain the final section thickness of 30 μm. The knurled screw was used for the setting of the section thickness. The prepared section was finally removed from the saw blade. The specimens were prepared for histology by the method as described by Donath and Breuner [49]. Subsequently, the sections were stained with...

Methods : Osseointegration of standard and mini de...

The specimens were dehydrated in the ascending graded ethanol solution and kept in a pre-filtration solution for 3 h at room temperature and then in the filtration solution at 4 °C for 17 h. The specimens were then embedded in a light curing resin Technovit 9100 NEW (Kulzer & Co., Wehrheim, Germany) polymerization system based on methyl methacrylate, specially developed for embedding mineraliz...

Methods : Osseointegration of standard and mini de...

Expected length of the procedure was approximately 1 h. Following placement of the implants, the wound was sutured in layers. The underlying muscle, fascia, and dermal layers were sutured with the help of Vicryl (Polyglactin 910) suture with 3/8 circle reverse cutting needle. The skin was sutured to a primary closer with the same suture material. Plain X-ray images of all the rabbit tibia were t...

Methods : Osseointegration of standard and mini de...

A small longitudinal skin incision just distal to the tibia-femur joint was made. The tibia/femur head was exposed subperiosteally and an osteotomy performed with the delicately placed pilot drill over the entry point and lightly pumped up and down under copius saline irrigation just to enter the cortical bone for the MDIs. This was used for initial bone drilling to depth of 0.5 mm. The 3M™ESPE...

Methods : Osseointegration of standard and mini de...

Nine clinically healthy New Zealand white rabbits weighing 3.5 kg and more were used for the study, and the animals were housed in the central animal house facility. The head of tibia/femur of the animals were used for the implantation of samples. Rabbits’ tibiae and femur have been widely used as an animal model by various other authors to study osseointegration of dental implants [36–45]. ...

Background : Osseointegration of standard and mini...

Despite the advantages of the mini dental implants, evidence on their efficacy and long-term success is lacking. The success of these implants will depend on their union with the surrounding bone. New implant systems entering into the market have to be studied with the help of animal models first, to demonstrate the osseointegration potential for their probable success in humans. There is a limite...

Background : Osseointegration of standard and mini...

The term “osseointegration” was first introduced to explain the phenomenon for stable fixation of titanium to bone by Brånemark et al. in the 1960s [1]. Osseointegrated implants were introduced, a new era in oral rehabilitation began, and many studies were conducted [2, 3]. A success rate of over 90% has been reported [4, 5]. Further, a success rate of 81% in the maxillary bone and 91% in the...

Abstract : Osseointegration of standard and mini d...

Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model. Nine New Zealand ...

Fig. 3. Mean bone loss at 6 months and 1 year. M...

Fig. 3. Mean bone loss at 6 months and 1 year. Mean bone loss distribution charts at 6 months and 1 year present no statistically significant difference. p value at 6 months was 0.2981 and at 1 year 0.6613 Fig. 3. Mean bone loss at 6 months and 1 year. Mean bone loss distribution charts at 6 months and 1 year present no statistically significant difference. p value at 6 months was ...

Fig. 2. ISQ values at placement, 6 weeks, 6 mont...

Fig. 2. ISQ values at placement, 6 weeks, 6 months, and 1 year. Mean and standard deviation of ISQ values taken at placement, 6 weeks, 6 months, and 1 year is presented. No statistical significant difference was determined between ISQ values at all time points. (p 

Fig. 1. Implant design. The OSPTX and OSP implants...

Fig. 1. Implant design. The OSPTX and OSP implants are manufactured from high-grade commercially pure titanium with surface roughness produced via a fluoride treatment process. The OSP implant is a screw-shaped self-tapping implant. The diameter used in this study was 4.0 mm. The implant length used in this study was 8 mm. The OSPTX implant has the same features as the OSP except the apex of t...

Table 2 Outcome success criteria : Comparative eva...

Implant success Clinically immobile when tested manually and/or with RFA (minimum ISQ = 65) Absence of peri-implant radiolucency present on an undistorted radiograph Absence of unresolved pain, discomfort, inf...

Table 1 Patient selection criteria : Comparative e...

Inclusion Male or female At least 18 years old Healthy enough to undergo routine implant surgery and subsequent dental treatment Partially edentulous requiring...

About this article : Comparative evaluation of the...

Simmons, D.E., Maney, P., Teitelbaum, A.G. et al. Comparative evaluation of the stability of two different dental implant designs and surgical protocols—a pilot study. Int J Implant Dent 3, 16 (2017). https://doi.org/10.1186/s40729-017-0078-2 Download citation Received: 18 January 2017 Accepted: 22 April 2017 Published: 02 May 2017 DOI: https://doi.org/10.1186/s40729-01...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Comparative evaluation of the...

Department of Periodontics, Louisiana State University Health Sciences Center School of Dentistry, 1100 Florida Avenue, New Orleans, LA, 70119, USA David E. Simmons, Pooja Maney, Austin G. Teitelbaum, Susan Billiot & A. Archontia Palaiologou Tulane University SPHTM, 1440 Canal St, Suite 2001, New Orleans, LA, 70130, USA Lomesh J. Popat You can also search for this author in PubMed Google...

References : Comparative evaluation of the stabili...

De Bruyn H, Raes F, Cooper LF, Reside G, Garriga JS, Tarrida LG, et al. Three-years clinical outcome of immediate provisionalization of single Osseospeed() implants in extraction sockets and healed ridges. Clin Oral Implants Res. 2013;24(2):217–23. Ebler S, Ioannidis A, Jung RE, Hammerle CH, Thoma DS. Prospective randomized controlled clinical study comparing two types of two-piece dental impla...

References : Comparative evaluation of the stabili...

O'Sullivan D, Sennerby L, Meredith N. Influence of implant taper on the primary and secondary stability of osseointegrated titanium implants. Clin Oral Implants Res. 2004;15(4):474–80. Schwartz-Arad D, Herzberg R, Levin L. Evaluation of long-term implant success. J Periodontol. 2005;76(10):1623–8. Alves CC, Neves M. Tapered implants: from indications to advantages. Int J Periodontics Restora...

References : Comparative evaluation of the stabili...

Anitua E, Orive G. Short implants in maxillae and mandibles: a retrospective study with 1 to 8 years of follow-up. J Periodontol. 2010;81(6):819–26. Feldman S, Boitel N, Weng D, Kohles SS, Stach RM. Five-year survival distributions of short-length (10 mm or less) machined-surfaced and Osseotite implants. Clin Implant Dent Relat Res. 2004;6(1):16–23. Felice P, Cannizzaro G, Checchi V, March...

Notes : Comparative evaluation of the stability of...

DENTSPLY International, Susquehanna Commerce Center, 221 West Philadelphia Street, York, PA 17401 I-CAT 17 19; Imaging Services International LLC, 1910 North Penn Rd., Hatfield, PA 19440 Intra-Lock International, 6560 S. West Rogers Circle, Suite 24, Boca Raton, FL 33487 Osstell USA, 6700 Alexander Bell Drive, Suite 200, Columbia, MD 21046 ImageJ 1.50i Wayne Rasband National Institutes of Heal...

Conclusions : Comparative evaluation of the stabil...

Survival rates and stability of OSP and OSPTX implants was comparable. Osteotomy preparation either by the standard or by the soft bone surgical protocol had no significant effect on implant survival, success, and stability. Insertion torque presented a moderate to strong correlation with ISQ values at 6 weeks, 6 months, and 1 year. Insertion torque presented a weak correlation to ISQ values...

Discussion : Comparative evaluation of the stabili...

Insertion torque presented a moderate to strong correlation with ISQ values at 6 weeks, 6 months, and 1 year but not at time of implant insertion. This finding is in agreement with Acil et al. who reported no statistically significant correlation between insertion torque and ISQ at time of implant placement [22]. Although a strong correlation was found between insertion torque and bone loss at...

Discussion : Comparative evaluation of the stabili...

Augmentation of the maxillary sinus prior to dental implant placement is routinely performed in order to help patients restore their maxillary posterior dentition. Unfortunately, not all patients are candidates for this procedure due to either health, personal, or financial concerns. An alternative treatment without the need for a sinus elevation procedure is the use of a shorter implant. Research...

Results : Comparative evaluation of the stability ...

Overall implant survival rate was 93.3%. Two implants failed, one implant in group A (OSPTXSoft) and one in group B (OSPTXStd). Both implant failures occurred at the time of uncovery (at 6 weeks) and prior to loading of the implants and were attributed to lack of integration. With the exception of these two failed implants, there was 100% success for all remaining implants using the parameters de...

Methods : Comparative evaluation of the stability ...

ANOVA was used to compare the mean implant stabilities between the three groups. Post hoc testing was done via Tukey’s honestly significant differences test to calculate the differences between ISQ measurements at the time of implant placement, 6 weeks and 6 and 12 months (Fig. 2) as well as bone levels at 6 and 12 months (Fig. 3). The correlations of multiple parameters such as insertion t...

Methods : Comparative evaluation of the stability ...

Following proper approval by the LSUHSC Institution Review Board (LSUNO IRB#7438), 27 (30 implant sites) systemically healthy patients at least 18 years old were enrolled in the study and randomly divided into three groups as follows (inclusion and exclusion criteria are described in detail in Table 1): Group A received 10 OSPTX implants using the soft bone surgical protocol (OSPTXSoft). Group...

Background : Comparative evaluation of the stabili...

A recent systematic review by Stocchero et al. concluded that an undersized drilling protocol in soft bone is an effective way to enhance insertion torque but recommended that further clinical studies are needed to confirm these data [18]. Our study was designed to address this question, as it compared the standard drilling protocol to a soft bone protocol. Our study hypothesis is that the stabil...

Background : Comparative evaluation of the stabili...

Dental implants are now a widely accepted treatment option for the replacement of missing teeth. The therapeutic goal of dental implants is to support restorations that replace single or multiple missing teeth so as to provide patient comfort, function, and esthetics as well as assist in the ongoing maintenance of remaining intraoral and perioral structures. However, anatomic limitations such as t...

Abstract : Comparative evaluation of the stability...

Survival and stability of OSPTX and OSP implants is comparable. Osteotomy preparation by either standard or soft bone surgical protocol presented no significant effect on implant survival and stability for the specific implant designs.

Abstract : Comparative evaluation of the stability...

The purpose of this study was to compare a parallel wall design implant to a tapered apex design implant when placed in the posterior maxilla using two different surgical protocols. Twenty-seven patients (30 implants) were divided into three groups. All implants were 4 mm wide in diameter and 8 mm long. Group A received 10 tapered implants (OSPTX) (Astra Tech OsseoSpeed TX™) using the soft b...

Fig. 7. a, b (The marginal discrepancy pattern for...

Fig. 7. face, 2: M4M surface) Units of the axis are in μm Fig. 7. a, b (The marginal discrepancy pattern for group CR and M4M). a Group CR (1: Ceramic surface, 2: CR surface) Units of the axis are in μm. b Group M4M (1: Ceramic surface, 2: M4M surface) Units of the axis are in μm

Fig. 6. Access-hole filling surface areas measurem...

Fig. 6. Access-hole filling surface areas measurement, average Fig. 6. Access-hole filling surface areas measurement, average

Fig. 5. Depth and angle at the margin : Comparison...

Fig. 5. Depth and angle at the margin Fig. 5. Depth and angle at the margin

Fig. 4. Margin depth measurement localization (exa...

Fig. 4. Margin depth measurement localization (example: TRA, T = 12 M) Fig. 4. Margin depth measurement localization (example: TRA, T = 12 M)

Fig. 3. a–e (Filling surface changes): a (ROG, T...

Fig. 3. a–e (Filling surface changes): a (ROG, T = 0). b (ROG, T = 1 M). c (ROG, T = 3 M). d (ROG, T = 6 M). e (ROG, T = 12 M) Fig. 3. a–e (Filling surface changes): a (ROG, T = 0). b (ROG, T = 1 M). c (ROG, T = 3 M). d (ROG, T = 6 M). e (ROG, T = 12 M)

Fig. 2. Occlusal contact point : Comparison of acc...

Fig. 2. Occlusal contact point Fig. 2. Occlusal contact point

Fig. 1. Brush-dip technique : Comparison of access...

Fig. 1. Brush-dip technique Fig. 1. Brush-dip technique

Table 4 Disappearance of the overfilling. Unit: % ...

  T = 1 M T = 3 M T = 6 M T = 12 M No disappearance CR 53.5% (15/28) 28.5% (8/28) 7.1% (2/28) 3.6% (1/28) 7.1% (2/28) M4M 28.6% (8/28) 10.7% (3/28) 28.5% (8/28) 28.5% (8/28) 3.6% (1/28)   Table 4 Disappearance of the overfilling. Unit: %

Table 3 Surface areas changes of access-hole filli...

  T = 1 M T = 3 M T = 6 M T = 12 M CR 100 93.2 87.6 83.3 M4M 100 91.1 83.2 77.1   Table 3 Surface areas changes of access-hole filling. Unit: %

Table 2 Aesthetical Outcomes at T = 12 M (VAS...

Patients PositionCR   Patients PositionM4M   T = 0 T = 12 T = 0 T = 12 AMB 13 10 7 AMB 23 10 7 14 6 5 24 8 3 16 8 8 26 8 5 17 10 10 27 8 5 ROG 24 10 7 ROG 14 10 6 26 10 10 16 10 7 27 10 10 17 10 7 NEU 11 4 3 NEU 21 6 5 13 8 7 23 6 5 16 8 7 25 10 10 ...

Table 1 ᅟ : Comparison of access-hole filling ma...

Materials Product names Batch numbers Manufacturer Ceramic primer Super-bond UCP FX1 Sun Medical Composite Fantasista GF11 Sun Medical Bonding agent Hybrid bond FS1/GL1 Sun Medical Adhesive composite Bondfill SB FT2/FS2/FS12 Sun Medical   Table 1 ᅟ

About this article : Comparison of access-hole fil...

Tanimura, R., Suzuki, S. Comparison of access-hole filling materials for screw retained implant prostheses: 12-month in vivo study. Int J Implant Dent 3, 19 (2017). https://doi.org/10.1186/s40729-017-0076-4 Download citation Received: 14 December 2016 Accepted: 22 April 2017 Published: 05 May 2017 DOI: https://doi.org/10.1186/s40729-017-0076-4

Rights and permissions : Comparison of access-hole...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Author information : Comparison of access-hole fil...

8, place du Général Catroux, 75017, Paris, France Rémy Tanimura Department of Clinical Community and Sciences, University of Alabama at Birmingham School of Dentistry, 1919 7th Avenue South, Birmingham, AL, 35294-0007, USA Shiro Suzuki You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar Correspondence to Rémy Tanimur...

Acknowledgements : Comparison of access-hole filli...

The authors thank Sun Medical Corporation for their material supply. RT and SS carried out the clinical data and their analysis. RT and SS have been involved in drafting the manuscript and approved the final version to be published. The authors, Rémy Tanimura and Shiro Suzuki, declare that they have no financial, commercial or any other competing interests. Springer Nature remains neutral with...

References : Comparison of access-hole filling mat...

de Pereira R P, Rocha CO, Reis JM, Arioli-Filho JN. Influence of sealing of the screw access hole on the fracture resistance of implant-supported restorations. Braz Dent J. 2016;27(2):148–52. Mihali S, Canjau S, Bratu E, Wang HL. Utilization of ceramic inlays for sealing implant prostheses screw access holes: a case-control study. Int J Oral Maxillofac Implants. 2016;31(5):1142–9. Download r...

References : Comparison of access-hole filling mat...

Taira Y, Sakai M, Sawase T. Effects of primer containing silane and thiophosphate monomers on bonding resin to a leucite-reinforced ceramic. J Dent. 2012;40(5):353–8. Kato H, Matsumura H, Tanaka T, Atsuta M. Bond strength and durability of porcelain bonding systems. J Prosthet Dent. 1996;75(2):163–8. Queiroz JR, Souza RO, Nogueira Junior Jr L, Ozcan M, Bottino MA. Influence of acid-etching a...

References : Comparison of access-hole filling mat...

Korsch M, Walther W. Peri-implantitis associated with type of cement: a retrospective analysis of different types of cement and their clinical correlation to the peri-implant tissue. Clin Implant Dent Relat Res. 2015;17(Suppl 2):e434–43. Linkevicius T, Vindasiute E, Puisys A, Linkeviciene L, Maslova N, Puriene A. The influence of the cementation margin position on the amount of undetected cemen...

References : Comparison of access-hole filling mat...

Millen C, Brägger U, Wittneben JG. Influence of prosthesis type and retention mechanism on complications with fixed implant-supported prostheses: a systematic review applying multivariate analyses. Int J Oral Maxillofac Implants. 2015;30(1):110–24. Guichet DL, Caputo AA, Choi H, Sorensen JA. Passivity of fit and marginal opening in screw- or cement-retained implant fixed partial denture desig...

Conclusions : Comparison of access-hole filling ma...

Within the limitation of the study, it was concluded that: The null-hypothesis “superficial and marginal deterioration of M4M and CR would not be significantly different” was accepted. The M4M (modified 4-META/MMA-TBB resin) and CR (composite resin) combined with a ceramic primer showed comparable characteristics (marginal integrity and wear behavior) in an access hole filling. The esthetic...

Discussion : Comparison of access-hole filling mat...

The analysis for the ratio of access-hole with or without marginal staining at the time of T = 12 M showed that the results in group CR (12/16) and in group M4M (12/16) were the same. For this reason, the marginal discrepancy pattern, different in both groups did not influence the aesthetical result. The occlusal contact point (A, B, or C) was compared to the marginal staining rate. Among the...

Discussion : Comparison of access-hole filling mat...

Focusing on numbers of access-hole showing a disappearance of the overfilling in an early period (up to T = 3 M), groups CR and M4M exhibited 82% (23/28) and 39.3% (11/28), respectively (Table 4). This can be explained by the differences of mechanical properties of both materials. The elastic moduli of M4M and CR are 1.9 and 7.9 MPa, respectively. Flexural strength of M4M is 66 MPa which i...

Discussion : Comparison of access-hole filling mat...

The in vivo evaluation is quite different from that of the in vitro analysis. In the previous study, all the specimens were calibrated to a flat surface with 2.5 mm diameter. In present study, each access hole had a different dimension and configuration. The filling surfaces were often ø3 to 4 mm in diameter. Access-holes located in the occlusal groove area or in the inclined cusp surface induc...

Discussion : Comparison of access-hole filling mat...

Nowadays, implant screw-retained prosthesis becomes a popular mode of implant supra-structure restoration. Cement retained implant restoration has issues including irretrievability and difficulty of controlling the cement excess beyond the abutment joint. The cement excess can be a major cause of peri-implantitis [13,14,15]. Screw-retained implant restoration has also some disadvantages including ...

Results : Comparison of access-hole filling materi...

Among the 56 access holes, no filling was dislodged during 12 months, and no complaint was registered from the patients regarding functional and aesthetical aspects. The results for surface areas changes of access-hole fillings at respective intervals were summarized in Table 3 and Fig. 6. The mean values of the change from T = 1 M to T = 12 M were 77.1 ± 13.1% for group M4M and...

Methods : Comparison of access-hole filling materi...

The marginal depth of the access-hole filling at T = 0, T = 1 M, T = 3 M, and T = 6 M could not be defined successfully because of the overfilling phenomenon which disrupted the measurement of marginal gap depth and angle (Fig. 3a–e). Only the marginal depth and angle at T = 12 M could be measured with the same digital microscope, and the mean value for each group was ca...

Methods : Comparison of access-hole filling materi...

Patients who received a metal framed ceramic screw retained implant crown or bridge were included in this study. These access holes were delimited only by ceramic. Those with metal surface exposure were excluded from this study. Patients with edentulous arch or section, full or partial denture as antagonists were excluded from the study. During the evaluation period, 2 patients (male) dropped out ...

Methods : Comparison of access-hole filling materi...

A total of 60 access-holes in 14 patients (5 male and 9 female) aging from 34 to 69 were restored and observed during 12 months. All subjects were informed about the study, and their written consent to participate in the study was taken. The materials used in this study are presented in Table 1. They include a phosphoric acid monomer ceramic primer (CP): UCP (Super-Bond Universal Ceramic Primer...

Background : Comparison of access-hole filling mat...

The retention of implant-supported prostheses is provided by the use of a screw or cement. Recently, it was demonstrated that cement-retained prostheses had a higher rate of technical and biological complications [1], despite a better passive fit than the screw-retained restorations [2]. The CAD/CAM development of the implant-supported prostheses allows a better passively fit with screw-retained p...

Abstract : Comparison of access-hole filling mater...

Screw retained implant prostheses seem to be an efficient restorative method to prevent peri-implantitis caused by cement excess around the abutment. The drawback of the screw-retained prostheses is the difficulty to realize an efficient access-hole filling functionally and aesthetically. Up to now, few in vitro and in vivo studies were reported in the literature. The aim of this study was to eval...

Fig. 5. Osteoblasts with an orientation tendency a...

Fig. 5. Osteoblasts with an orientation tendency after 24 h of rotation (phallacidin fluorescence staining). On the left side with 200× and on the right side with 400× magnification. The yellow arrows show the orientation of the cells. The red arched arrow within the coloured circle shows the direction of rotation. The dashed white line oriented to the right stands for the resulting centrifug...

Fig. 4. Randomly orientated osteoblasts without in...

Fig. 4. Randomly orientated osteoblasts without influence of rotation (phallacidin fluorescence staining). On the left side with 200× and on the right side with 400× magnification. The white X on the coloured circle marks the location upon the plate where the osteoblasts were located. The red X marks the centre of the plate Fig. 4. Randomly orientated osteoblasts without influence of rotati...

Fig. 3. Diagram for visualisation of the calculati...

centrifugal force and the glass plates’ dimensions. For example, at a distance of 25 mm from the centre of the upper plate, the shear forces’ value is 8.33 dyn/cm2, together with an additional centrifugal force that has a value of 0.55 dyn/cm2 Fig. 3. Diagram for visualisation of the calculation of shear stress rates taking into account the centrifugal force and the glass plates’ dim...

Fig. 2. Side view of a computerized simulation, sh...

earing gap and bottom plate are shown on the left side; rotation speed = 200 rpm; colour code bar (left edge) showing shear force values [Pa] [1 Pa = 10 dyn/cm2]; flow direction presented by arrows Fig. 2. Side view of a computerized simulation, showing the flow chambers’ lower compartment and the flow profile in between the two plates; shearing gap and bottom plate are shown on ...

Fig. 1. Three-dimensional illustration (a–e) and...

Fig. 1. Three-dimensional illustration (a–e) and photography (f) of the experimental setup with the components marked numerical. a as the lower plate); 2 Rotating glass panel [60 mm diameter (cell bearing)]; 3 Titanium axis. b4 Liquid medium (red). cGearwheel with set screw. eng ring with additional set screw Fig. 1. Three-dimensional illustration (a–e) and photography (f) of the experim...

Table 2 Listing of the culture media and additives...

Culture medium/additives Manufacturer Order no. Concentration Dulbecco’s modified Eagle medium (DMEM) with l-glutamine, plus 4.5 g glucose,...

Table 1 Listing of the single components of the fl...

Component Manufacturer Order no. Large petri dish Becton Dickinson, Franklin Lakes, NJ, USA ...

About this article : Cellular fluid shear stress o...

Kämmerer, P.W., Thiem, D.G.E., Alshihri, A. et al. Cellular fluid shear stress on implant surfaces—establishment of a novel experimental set up. Int J Implant Dent 3, 22 (2017). https://doi.org/10.1186/s40729-017-0085-3 Download citation Received: 27 February 2017 Accepted: 22 May 2017 Published: 31 May 2017 DOI: https://doi.org/10.1186/s40729-017-0085-3

Rights and permissions : Cellular fluid shear stre...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Cellular fluid shear stress o...

Correspondence to D. G. E. Thiem.

Author information : Cellular fluid shear stress o...

Department of Oral and Maxillofacial Surgery, Facial Plastic Surgery, University Medical Centre Rostock, Schillingallee 35, 18057, Rostock, Germany P. W. Kämmerer & D. G. E. Thiem Department of Prosthetic and Biomaterial Sciences, King Saud University, Riyadh, Saudi Arabia A. Alshihri Harvard School of Dental Medicine, Boston, MA, USA A. Alshihri Department of Oral and Maxillofacial Surge...

Acknowledgements : Cellular fluid shear stress on ...

The authors thank the Department of Hydraulic Machines, Faculty of Mechanical Engineering, Technical University of Munich, Germany, for helping with the computerised simulations. Nothing to declare The datasets supporting the conclusions of this article are available at the repository of the University Medical Centre Mainz, Germany, and can be provided on request. PK had substantial contributio...

References : Cellular fluid shear stress on implan...

Papadaki M, Eskin SG. Effects of fluid shear stress on gene regulation of vascular cells. Biotechnol Prog. 1997;13(3):209–21. James NL, Harrison DG, Nerem RM. Effects of shear on endothelial cell calcium in the presence and absence of ATP. FASEB J. 1995;9(10):968–73. Kämmerer PW, Lehnert M, Al-Nawas B, Kumar VV, Hagmann S, Alshihri A, et al. Osseoconductivity of a specific streptavidin-biot...

References : Cellular fluid shear stress on implan...

Hughes-Fulford M. Signal transduction and mechanical stress. Sci STKE. 2004;2004(249):RE12. Ruel J, Lemay J, Dumas G, Doillon C, Charara J. Development of a parallel plate flow chamber for studying cell behavior under pulsatile flow. ASAIO J. 1995;41(4):876–83. Kazakidi A, Sherwin SJ, Weinberg PD. Effect of Reynolds number and flow division on patterns of haemodynamic wall shear stress near br...

References : Cellular fluid shear stress on implan...

Becker J, Kirsch A, Schwarz F, Chatzinikolaidou M, Rothamel D, Lekovic V, et al. Bone apposition to titanium implants biocoated with recombinant human bone morphogenetic protein-2 (rhBMP-2). A pilot study in dogs. Clin Oral Investig. 2006;10(3):217–24. Hung CT, Allen FD, Pollack SR, Brighton CT. What is the role of the convective current density in the real-time calcium response of cultured bon...

References : Cellular fluid shear stress on implan...

Ehrlich PJ, Lanyon LE. Mechanical strain and bone cell function: a review. Osteoporos Int. 2002;13(9):688–700. Vaughan TJ, Haugh MG, Mcnamara LM. A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems. J R Soc Interface. 2013;10(81):20120900. Weinbaum S, Cowin SC, Zeng Y. A model for the excitation of osteocytes by mechanical loading-in...

Abbreviations : Cellular fluid shear stress on imp...

Fluid shear stress

Conclusions : Cellular fluid shear stress on impla...

To create fluid shear stress under in vitro conditions, several flow chambers have been developed in the past. The experimental setup of the flow chamber in the centre of this study offers advantages such as simplicity to assemble and ease of use as well as the creation of reproducible fluid shear forces on cells. Due to the new design, different cell types could be simultaneously analysed under r...

Discussion : Cellular fluid shear stress on implan...

Besides, in the model reported in this study, microscopic examinations are possible after completing the experiment only. Nevertheless, an advantage of the new flow chamber is the possibility of testing different cell colonies simultaneously in one single experiment by placing cells in different radial locations on the spinning disc. Due to the current flow gradient from the centre to the peripher...

Discussion : Cellular fluid shear stress on implan...

Due to the fact that constant flows were generated within the parallel flow chamber only, the situations of in vitro experiments differ from in vivo setting where dynamic flow profiles are particular [33]. As the constant laminar flow profile is not physiological in bones [34], vessels and other tissues [35], the informative value of the experimental setting is limited but it could be used for var...

Discussion : Cellular fluid shear stress on implan...

The aim of this study was to establish a new FSS model that is easy to use as well as simple to assemble in order to create reproducible fluid shear forces on cells close to implant material surfaces. Todays’ commonly used commercial flow devices differ in geometry and function, which makes comparisons between experiments difficult [4, 10, 26, 27]. The benefits of this novel testing device are r...

Results : Cellular fluid shear stress on implant s...

in which ρ = density, h = height, ω = angular velocity and r = radius. Figure 3 shows the respective physical force and its dependence on a bigger radius and higher rotational speed. The results of this study indicate that the centrifugal force represents only a little proportion of effective forces. Hence, the centrifugal forces’ impacts on the tested cells are considered to be insignifican...

Results : Cellular fluid shear stress on implant s...

Our analysis was focused on two main aspects: Simulation of the fluid flow characteristics as well as quantification of the arising shear forces at the plate/plate flow chamber with reliable reproducibility Assessment of the impact of fluid shear stress on osteoblast cells in terms of altered cell morphology and intracellular structural changes The computational fluid dynamic analysis and the q...

Methods : Cellular fluid shear stress on implant s...

For constant and fully developed laminar flow between the two parallel plates, the magnitude of the wall shear stress (τ) in between was calculated by formula 1: in which η is the dynamic fluid viscosity (dyn/cm2), r is the radius of the plate (cm), ω stands for angular velocity and H for height (vertical distance in between the two plates). To get information whether the flow is laminar or t...

Methods : Cellular fluid shear stress on implant s...

A three-dimensional illustration and photography of the plate/plate flow chamber model is shown in Fig. 1. A detailed list of used parts can be found in Appendix 1. The circulation within the flow chamber was generated by an externally attached electric motor, which rotates up to 500 rounds per minute (rpm). A commercial grade 4 pure medical titanium gear shaft (length = 40 mm, diameter =...

Background : Cellular fluid shear stress on implan...

Therefore, the aim of the present study was to establish a new cell chamber model for FSS simulation and stimulation. In addition to its ease of use, the reported model in this study should meet the requirements of a simple design, generating reproducible flow characteristics next to laminar flows and clearly defined flow gradients on implant surfaces.

Background : Cellular fluid shear stress on implan...

Cells can be influenced by different mechanostimuli, which lead to an activation of cellular and inter-cellular responses. These reactions may be caused by either a direct stimulation of the cell body (mechanoreception) or indirect cellular stimulation (response) [1,2,3]. Extracellular fluid movement induces fluid shear stress (FSS) that can result in different cellular processes including prolife...

Abstract : Cellular fluid shear stress on implant ...

Mechanostimuli of different cells can affect a wide array of cellular and inter-cellular biological processes responsible for dental implant healing. The purpose of this in vitro study was to establish a new test model to create a reproducible flow-induced fluid shear stress (FSS) of osteoblast cells on implant surfaces. As FSS effects on osteoblasts are detectable at 10 dyn/cm2, a custom-made f...

Fig. 7. a, b (The marginal discrepancy pattern for...

Fig. 7. CR and M4M). a Group CR (1: Ceramic surface, 2: CR surface) Units of the axis are in μm. b Group M4M (1: Ceramic surface, 2: M4M surface) Units of the axis are in μm Fig. 7. a, b (The marginal discrepancy pattern for group CR and M4M). a Group CR (1: Ceramic surface, 2: CR surface) Units of the axis are in μm. b Group M4M (1: Ceramic surface, 2: M4M surface) Units of the axis are i...

Fig. 6. Access-hole filling surface areas measurem...

Fig. 6. Access-hole filling surface areas measurement, average Fig. 6. Access-hole filling surface areas measurement, average

Fig. 5. Depth and angle at the margin : Comparison...

Fig. 5. Depth and angle at the margin Fig. 5. Depth and angle at the margin

Fig. 4. Margin depth measurement localization (exa...

Fig. 4. Margin depth measurement localization (example: TRA, T = 12 M) Fig. 4. Margin depth measurement localization (example: TRA, T = 12 M)

Fig. 3. a–e (Filling surface changes): a (ROG, T...

Fig. 3. ROG, T = 1 M). c (ROG, T = 3 M). d (ROG, T = 6 M). e (ROG, T = 12 M) Fig. 3. a–e (Filling surface changes): a (ROG, T = 0). b (ROG, T = 1 M). c (ROG, T = 3 M). d (ROG, T = 6 M). e (ROG, T = 12 M)

Fig. 2. Occlusal contact point : Comparison of acc...

Fig. 2. Occlusal contact point Fig. 2. Occlusal contact point

Fig. 1. Brush-dip technique : Comparison of access...

Fig. 1. Brush-dip technique Fig. 1. Brush-dip technique

Table 4 Disappearance of the overfilling. Unit: % ...

  T = 1 M T = 3 M T = 6 M T = 12 M No disappearance CR 53.5% (15/28) ...

Table 3 Surface areas changes of access-hole filli...

  T = 1 M T = 3 M T = 6 M T = 12 M CR 100 93.2 87.6 ...

Table 2 Aesthetical Outcomes at T = 12 M (VAS...

Patients Position CR   Patients Position M4M   T = 0 T = 12 ...

Table 1 ᅟ : Comparison of access-hole filling ma...

Materials Product names Batch numbers Manufacturer Ceramic primer Super-bond UCP ...

About this article : Comparison of access-hole fil...

Tanimura, R., Suzuki, S. Comparison of access-hole filling materials for screw retained implant prostheses: 12-month in vivo study. Int J Implant Dent 3, 19 (2017). https://doi.org/10.1186/s40729-017-0076-4 Download citation Received: 14 December 2016 Accepted: 22 April 2017 Published: 05 May 2017 DOI: https://doi.org/10.1186/s40729-017-0076-4

Rights and permissions : Comparison of access-hole...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Comparison of access-hole fil...

8, place du Général Catroux, 75017, Paris, France Rémy Tanimura Department of Clinical Community and Sciences, University of Alabama at Birmingham School of Dentistry, 1919 7th Avenue South, Birmingham, AL, 35294-0007, USA Shiro Suzuki You can also search for this author in PubMed Google Scholar You can also search for this author in PubMe...

Acknowledgements : Comparison of access-hole filli...

The authors thank Sun Medical Corporation for their material supply. RT and SS carried out the clinical data and their analysis. RT and SS have been involved in drafting the manuscript and approved the final version to be published. The authors, Rémy Tanimura and Shiro Suzuki, declare that they have no financial, commercial or any other competing interests. Springer Nature remains neutral with...

References : Comparison of access-hole filling mat...

de Pereira R P, Rocha CO, Reis JM, Arioli-Filho JN. Influence of sealing of the screw access hole on the fracture resistance of implant-supported restorations. Braz Dent J. 2016;27(2):148–52. Mihali S, Canjau S, Bratu E, Wang HL. Utilization of ceramic inlays for sealing implant prostheses screw access holes: a case-control study. Int J Oral Maxillofac Implants. 2016;31(5):1142–9. Download r...

References : Comparison of access-hole filling mat...

Taira Y, Sakai M, Sawase T. Effects of primer containing silane and thiophosphate monomers on bonding resin to a leucite-reinforced ceramic. J Dent. 2012;40(5):353–8. Kato H, Matsumura H, Tanaka T, Atsuta M. Bond strength and durability of porcelain bonding systems. J Prosthet Dent. 1996;75(2):163–8. Queiroz JR, Souza RO, Nogueira Junior Jr L, Ozcan M, Bottino MA. Influence of acid-etching a...

References : Comparison of access-hole filling mat...

Korsch M, Walther W. Peri-implantitis associated with type of cement: a retrospective analysis of different types of cement and their clinical correlation to the peri-implant tissue. Clin Implant Dent Relat Res. 2015;17(Suppl 2):e434–43. Linkevicius T, Vindasiute E, Puisys A, Linkeviciene L, Maslova N, Puriene A. The influence of the cementation margin position on the amount of undetected cemen...

References : Comparison of access-hole filling mat...

Millen C, Brägger U, Wittneben JG. Influence of prosthesis type and retention mechanism on complications with fixed implant-supported prostheses: a systematic review applying multivariate analyses. Int J Oral Maxillofac Implants. 2015;30(1):110–24. Guichet DL, Caputo AA, Choi H, Sorensen JA. Passivity of fit and marginal opening in screw- or cement-retained implant fixed partial denture desig...

Conclusions : Comparison of access-hole filling ma...

Within the limitation of the study, it was concluded that: The null-hypothesis “superficial and marginal deterioration of M4M and CR would not be significantly different” was accepted. The M4M (modified 4-META/MMA-TBB resin) and CR (composite resin) combined with a ceramic primer showed comparable characteristics (marginal integrity and wear behavior) in an access hole filling. The esthetic...

Discussion : Comparison of access-hole filling mat...

The analysis for the ratio of access-hole with or without marginal staining at the time of T = 12 M showed that the results in group CR (12/16) and in group M4M (12/16) were the same. For this reason, the marginal discrepancy pattern, different in both groups did not influence the aesthetical result. The occlusal contact point (A, B, or C) was compared to the marginal staining rate. Among the...

Discussion : Comparison of access-hole filling mat...

Focusing on numbers of access-hole showing a disappearance of the overfilling in an early period (up to T = 3 M), groups CR and M4M exhibited 82% (23/28) and 39.3% (11/28), respectively (Table 4). This can be explained by the differences of mechanical properties of both materials. The elastic moduli of M4M and CR are 1.9 and 7.9 MPa, respectively. Flexural strength of M4M is 66 MPa which i...

Discussion : Comparison of access-hole filling mat...

The in vivo evaluation is quite different from that of the in vitro analysis. In the previous study, all the specimens were calibrated to a flat surface with 2.5 mm diameter. In present study, each access hole had a different dimension and configuration. The filling surfaces were often ø3 to 4 mm in diameter. Access-holes located in the occlusal groove area or in the inclined cusp surface induc...

Discussion : Comparison of access-hole filling mat...

Nowadays, implant screw-retained prosthesis becomes a popular mode of implant supra-structure restoration. Cement retained implant restoration has issues including irretrievability and difficulty of controlling the cement excess beyond the abutment joint. The cement excess can be a major cause of peri-implantitis [13,14,15]. Screw-retained implant restoration has also some disadvantages including ...

Results : Comparison of access-hole filling materi...

Among the 56 access holes, no filling was dislodged during 12 months, and no complaint was registered from the patients regarding functional and aesthetical aspects. The results for surface areas changes of access-hole fillings at respective intervals were summarized in Table 3 and Fig. 6. The mean values of the change from T = 1 M to T = 12 M were 77.1 ± 13.1% for group M4M and...

Methods : Comparison of access-hole filling materi...

The marginal depth of the access-hole filling at T = 0, T = 1 M, T = 3 M, and T = 6 M could not be defined successfully because of the overfilling phenomenon which disrupted the measurement of marginal gap depth and angle (Fig. 3a–e). Only the marginal depth and angle at T = 12 M could be measured with the same digital microscope, and the mean value for each group was ca...

Methods : Comparison of access-hole filling materi...

Patients who received a metal framed ceramic screw retained implant crown or bridge were included in this study. These access holes were delimited only by ceramic. Those with metal surface exposure were excluded from this study. Patients with edentulous arch or section, full or partial denture as antagonists were excluded from the study. During the evaluation period, 2 patients (male) dropped out ...

Methods : Comparison of access-hole filling materi...

A total of 60 access-holes in 14 patients (5 male and 9 female) aging from 34 to 69 were restored and observed during 12 months. All subjects were informed about the study, and their written consent to participate in the study was taken. The materials used in this study are presented in Table 1. They include a phosphoric acid monomer ceramic primer (CP): UCP (Super-Bond Universal Ceramic Primer...

Background : Comparison of access-hole filling mat...

The retention of implant-supported prostheses is provided by the use of a screw or cement. Recently, it was demonstrated that cement-retained prostheses had a higher rate of technical and biological complications [1], despite a better passive fit than the screw-retained restorations [2]. The CAD/CAM development of the implant-supported prostheses allows a better passively fit with screw-retained p...

Abstract : Comparison of access-hole filling mater...

Screw retained implant prostheses seem to be an efficient restorative method to prevent peri-implantitis caused by cement excess around the abutment. The drawback of the screw-retained prostheses is the difficulty to realize an efficient access-hole filling functionally and aesthetically. Up to now, few in vitro and in vivo studies were reported in the literature. The aim of this study was to eval...

Fig. 5. Osteoblasts with an orientation tendency a...

Fig. 5. Osteoblasts with an orientation tendency after 24 h of rotation (phallacidin fluorescence staining). On the left side with 200× and on the right side with 400× magnification. The yellow arrows show the orientation of the cells. The red arched arrow within the coloured circle shows the direction of rotation. The dashed white line oriented to the right stands for the resulting centrifug...

Fig. 4. Randomly orientated osteoblasts without in...

Fig. 4. Randomly orientated osteoblasts without influence of rotation (phallacidin fluorescence staining). On the left side with 200× and on the right side with 400× magnification. The white X on the coloured circle marks the location upon the plate where the osteoblasts were located. The red X marks the centre of the plate Fig. 4. Randomly orientated osteoblasts without influence of rotati...

Fig. 3. Diagram for visualisation of the calculati...

to account the centrifugal force and the glass plates’ dimensions. For example, at a distance of 25 mm from the centre of the upper plate, the shear forces’ value is 8.33 dyn/cm2, together with an additional centrifugal force that has a value of 0.55 dyn/cm2 Fig. 3. Diagram for visualisation of the calculation of shear stress rates taking into account the centrifugal force and the glas...

Fig. 2. Side view of a computerized simulation, sh...

e in between the two plates; shearing gap and bottom plate are shown on the left side; rotation speed = 200 rpm; colour code bar (left edge) showing shear force values [Pa] [1 Pa = 10 dyn/cm2]; flow direction presented by arrows Fig. 2. Side view of a computerized simulation, showing the flow chambers’ lower compartment and the flow profile in between the two plates; shearing gap...

Fig. 1. Three-dimensional illustration (a–e) and...

Fig. 1. Three-dimensional illustration (a–e) and photography (f) of the experimental setup with the components marked numerical. a lower plate); 2 Rotating glass panel [60 mm diameter (cell bearing)]; 3 Titanium axis. b4 Liquid medium (red). cwheel with set screw. e ring with additional set screw Fig. 1. Three-dimensional illustration (a–e) and photography (f) of the experimental setup w...

Table 2 Listing of the culture media and additives...

Culture medium/additives Manufacturer Order no. Concentration Dulbecco’s modified Eagle medium (DMEM) with l-glutamine, plus 4.5 g glucose,...

Table 1 Listing of the single components of the fl...

Component Manufacturer Order no. Large petri dish Becton Dickinson, Franklin Lakes, NJ, USA ...

About this article : Cellular fluid shear stress o...

Kämmerer, P.W., Thiem, D.G.E., Alshihri, A. et al. Cellular fluid shear stress on implant surfaces—establishment of a novel experimental set up. Int J Implant Dent 3, 22 (2017). https://doi.org/10.1186/s40729-017-0085-3 Download citation Received: 27 February 2017 Accepted: 22 May 2017 Published: 31 May 2017 DOI: https://doi.org/10.1186/s40729-017-0085-3

Rights and permissions : Cellular fluid shear stre...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Cellular fluid shear stress o...

Correspondence to D. G. E. Thiem.

Author information : Cellular fluid shear stress o...

Department of Oral and Maxillofacial Surgery, Facial Plastic Surgery, University Medical Centre Rostock, Schillingallee 35, 18057, Rostock, Germany P. W. Kämmerer & D. G. E. Thiem Department of Prosthetic and Biomaterial Sciences, King Saud University, Riyadh, Saudi Arabia A. Alshihri Harvard School of Dental Medicine, Boston, MA, USA A. Alshihri Department of Oral and Maxillofacial Surge...

Acknowledgements : Cellular fluid shear stress on ...

The authors thank the Department of Hydraulic Machines, Faculty of Mechanical Engineering, Technical University of Munich, Germany, for helping with the computerised simulations. Nothing to declare The datasets supporting the conclusions of this article are available at the repository of the University Medical Centre Mainz, Germany, and can be provided on request. PK had substantial contributio...

References : Cellular fluid shear stress on implan...

Papadaki M, Eskin SG. Effects of fluid shear stress on gene regulation of vascular cells. Biotechnol Prog. 1997;13(3):209–21. James NL, Harrison DG, Nerem RM. Effects of shear on endothelial cell calcium in the presence and absence of ATP. FASEB J. 1995;9(10):968–73. Kämmerer PW, Lehnert M, Al-Nawas B, Kumar VV, Hagmann S, Alshihri A, et al. Osseoconductivity of a specific streptavidin-biot...

References : Cellular fluid shear stress on implan...

Hughes-Fulford M. Signal transduction and mechanical stress. Sci STKE. 2004;2004(249):RE12. Ruel J, Lemay J, Dumas G, Doillon C, Charara J. Development of a parallel plate flow chamber for studying cell behavior under pulsatile flow. ASAIO J. 1995;41(4):876–83. Kazakidi A, Sherwin SJ, Weinberg PD. Effect of Reynolds number and flow division on patterns of haemodynamic wall shear stress near br...

References : Cellular fluid shear stress on implan...

Becker J, Kirsch A, Schwarz F, Chatzinikolaidou M, Rothamel D, Lekovic V, et al. Bone apposition to titanium implants biocoated with recombinant human bone morphogenetic protein-2 (rhBMP-2). A pilot study in dogs. Clin Oral Investig. 2006;10(3):217–24. Hung CT, Allen FD, Pollack SR, Brighton CT. What is the role of the convective current density in the real-time calcium response of cultured bon...

References : Cellular fluid shear stress on implan...

Ehrlich PJ, Lanyon LE. Mechanical strain and bone cell function: a review. Osteoporos Int. 2002;13(9):688–700. Vaughan TJ, Haugh MG, Mcnamara LM. A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems. J R Soc Interface. 2013;10(81):20120900. Weinbaum S, Cowin SC, Zeng Y. A model for the excitation of osteocytes by mechanical loading-in...

Abbreviations : Cellular fluid shear stress on imp...

Fluid shear stress

Conclusions : Cellular fluid shear stress on impla...

To create fluid shear stress under in vitro conditions, several flow chambers have been developed in the past. The experimental setup of the flow chamber in the centre of this study offers advantages such as simplicity to assemble and ease of use as well as the creation of reproducible fluid shear forces on cells. Due to the new design, different cell types could be simultaneously analysed under r...

Discussion : Cellular fluid shear stress on implan...

Besides, in the model reported in this study, microscopic examinations are possible after completing the experiment only. Nevertheless, an advantage of the new flow chamber is the possibility of testing different cell colonies simultaneously in one single experiment by placing cells in different radial locations on the spinning disc. Due to the current flow gradient from the centre to the peripher...

Discussion : Cellular fluid shear stress on implan...

Due to the fact that constant flows were generated within the parallel flow chamber only, the situations of in vitro experiments differ from in vivo setting where dynamic flow profiles are particular [33]. As the constant laminar flow profile is not physiological in bones [34], vessels and other tissues [35], the informative value of the experimental setting is limited but it could be used for var...

Discussion : Cellular fluid shear stress on implan...

The aim of this study was to establish a new FSS model that is easy to use as well as simple to assemble in order to create reproducible fluid shear forces on cells close to implant material surfaces. Todays’ commonly used commercial flow devices differ in geometry and function, which makes comparisons between experiments difficult [4, 10, 26, 27]. The benefits of this novel testing device are r...

Results : Cellular fluid shear stress on implant s...

in which ρ = density, h = height, ω = angular velocity and r = radius. Figure 3 shows the respective physical force and its dependence on a bigger radius and higher rotational speed. The results of this study indicate that the centrifugal force represents only a little proportion of effective forces. Hence, the centrifugal forces’ impacts on the tested cells are considered to be insignifican...

Results : Cellular fluid shear stress on implant s...

Our analysis was focused on two main aspects: Simulation of the fluid flow characteristics as well as quantification of the arising shear forces at the plate/plate flow chamber with reliable reproducibility Assessment of the impact of fluid shear stress on osteoblast cells in terms of altered cell morphology and intracellular structural changes The computational fluid dynamic analysis and the q...

Methods : Cellular fluid shear stress on implant s...

For constant and fully developed laminar flow between the two parallel plates, the magnitude of the wall shear stress (τ) in between was calculated by formula 1: in which η is the dynamic fluid viscosity (dyn/cm2), r is the radius of the plate (cm), ω stands for angular velocity and H for height (vertical distance in between the two plates). To get information whether the flow is laminar or t...

Methods : Cellular fluid shear stress on implant s...

A three-dimensional illustration and photography of the plate/plate flow chamber model is shown in Fig. 1. A detailed list of used parts can be found in Appendix 1. The circulation within the flow chamber was generated by an externally attached electric motor, which rotates up to 500 rounds per minute (rpm). A commercial grade 4 pure medical titanium gear shaft (length = 40 mm, diameter =...

Background : Cellular fluid shear stress on implan...

Therefore, the aim of the present study was to establish a new cell chamber model for FSS simulation and stimulation. In addition to its ease of use, the reported model in this study should meet the requirements of a simple design, generating reproducible flow characteristics next to laminar flows and clearly defined flow gradients on implant surfaces.

Background : Cellular fluid shear stress on implan...

Cells can be influenced by different mechanostimuli, which lead to an activation of cellular and inter-cellular responses. These reactions may be caused by either a direct stimulation of the cell body (mechanoreception) or indirect cellular stimulation (response) [1,2,3]. Extracellular fluid movement induces fluid shear stress (FSS) that can result in different cellular processes including prolife...

Abstract : Cellular fluid shear stress on implant ...

Mechanostimuli of different cells can affect a wide array of cellular and inter-cellular biological processes responsible for dental implant healing. The purpose of this in vitro study was to establish a new test model to create a reproducible flow-induced fluid shear stress (FSS) of osteoblast cells on implant surfaces. As FSS effects on osteoblasts are detectable at 10 dyn/cm2, a custom-made f...

Fig. 7 Second stage surgery of patient in Fig. 1. ...

Fig. 7 Second stage surgery of patient in Fig. 1. a Vestibular depth reduction after augmentation and implant placement. b Partial thickness and apical repositioned flap. c CMX healing and soft tissue dehiscence with CCXBB exposure. d Dehiscence healing after re-contouring and buccal emergency profile. e Buccal aspect of the final restoration. f Buccal ridge contour

Fig. 6 Immunohistochemical analysis of slices from...

Fig. 6 Immunohistochemical analysis of slices from the same sample with four different markers. a TRAP. b OPN. c ALP. d OSC

Fig. 5. Survival rate of dental implants after aut...

Fig. 5. Survival rate of dental implants after autologous bone augmentation Fig. 5. Survival rate of dental implants after autologous bone augmentation

Fig. 4. Postoperative nerve alterations. Single as...

Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Double asterisk, N refers to the total number of the surgical approaches in the maxilla (N = 225) Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Dou...

Fig. 3. Surgical outcome after autologous augmenta...

Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites

Fig. 2. Survival rate of autologous bone grafts : ...

Fig. 2. Survival rate of autologous bone grafts Fig. 2. Survival rate of autologous bone grafts

Fig. 1. Postoperative complications at the donor a...

Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378) Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378)

Table 3 Intra- and postoperative complications aft...

Postoperative complications %/procedures (N) At donor sitea    Wound infection 2.6% (8/300) At recipient site...

Table 2 Donor sites and numbers of bone grafts as ...

Donor site Bone grafts (N)/patients (N) Lateral zygomatic buttress 113/112 Mandibular ramus (retromolar) ...

Table 1 Patient characteristics at the time of aug...

Patient characteristics N (%) Gendera    Male 250 (89.6%)  Female 29 (10.4%) ...

About this article : Autogenous bone grafts in ora...

Sakkas, A., Wilde, F., Heufelder, M. et al. Autogenous bone grafts in oral implantology—is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J Implant Dent 3, 23 (2017). https://doi.org/10.1186/s40729-017-0084-4 Download citation Received: 27 February 2017 Accepted: 22 May 2017 Published: 01 June 2017 DOI: https://doi...

Rights and permissions : Autogenous bone grafts in...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Autogenous bone grafts in ora...

Department of Oral and Plastic Maxillofacial Surgery, Military Hospital Ulm, Academic Hospital of the University of Ulm, Oberer Eselsberg 40, 89081, Ulm, Germany Andreas Sakkas, Frank Wilde, Marcus Heufelder & Alexander Schramm Institute of Anatomy, Medical Faculty of Leipzig University, Leipzig, Germany Karsten Winter Department of Oral and Plastic Maxillofacial Surgery, University Hospit...

Acknowledgements : Autogenous bone grafts in oral ...

The authors thank the patients for their kindness to participate as study cases and the whole medical team at the Bundeswehrkrankenhaus Ulm. AS participated in its design and coordination, carried out the data selection, and drafted the manuscript, and is the corresponding author. FW participated in its design and coordination and helped in drafting the manuscript. MH participated in its design a...

References : Autogenous bone grafts in oral implan...

Semper W, Kraft S, Mehrhof J, Nelson K. Impact of abutment rotation and angulation on marginal fit: theoretical considerations. Int J Oral Maxillofac Implants. 2010;25:752–8. Wiltfang J, Jätschmann N, Hedderich J, Neukam FW, Schlegel KA, Gierloff M. Effect of deproteinized bovine bone matrix coverage on the resorption of iliac cortico-spongeous bone grafts—a prospective study of two cohorts....

References : Autogenous bone grafts in oral implan...

Chiapasco M, Zaniboni M. Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations: a systematic review. Clin Oral Implants Res. 2009;20:113–23. Felice P, Pellegrino G, Checchi L, Pistilli R, Esposito M. Vertical augmentation with interpositional blocks of anorganic bovine bone vs. 7-mm-long implants in posterior mandibles: 1-year results of a randomized clinical...

References : Autogenous bone grafts in oral implan...

Verdugo F, Castillo A, Moragues MD, Pontón J. Bone microbial contamination influences autogenous grafting in sinus augmentation. J Periodontol. 2009;80:1355–64. Wiltfang J, Schultze-Mosgau S, Merten HA, Kessler P, Ludwig A, Engelke W. Endoscopic and ultrasonographic evaluation of the maxillary sinus after combined sinus floor augmentation and implant insertion. Oral Surg Oral Med Oral Pathol O...

References : Autogenous bone grafts in oral implan...

von Arx T, Buser D. Horizontal ridge augmentation using autogenous block grafts and the guided bone regeneration technique with collagen membranes: a clinical study with 42 patients. Clin Oral Implants Res. 2006;17:359–66. Levin L, Nitzan D, Schwartz-Arad D. Success of dental implants placed in intraoral block bone grafts. J Periodontol. 2007;78:18–21. Andersson L. Patient self-evaluation of...

References : Autogenous bone grafts in oral implan...

Aghaloo TL, Moy PK. Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement? Int J Oral Maxillofac Implants. 2007;22:49–70. Margonar R, dos Santos PL, Queiroz TP, Marcantonio E. Rehabilitation of atrophic maxilla using the combination of autogenous and allogeneic bone grafts followed by protocol-type prosthesis. J Craniofac Surg. 2010;2...

References : Autogenous bone grafts in oral implan...

Schwartz-Arad D, Dori S. Intraoral autogenous onlay block bone grafting for implant dentistry. Refuat Hapeh Vehashinayim. 2002;19:35–9. 77. Misch CM. Ridge augmentation using mandibular ramus bone grafts for the placement of dental implants: presentation of a technique. Pract Periodontics Aesthet Dent. 1996;8:127–35. Altiparmak N, Soydan SS, Uckan S. The effect of conventional surgery and pi...

References : Autogenous bone grafts in oral implan...

Jensen AT, Jensen SS, Worsaae N. Complications related to bone augmentation procedures of localized defects in the alveolar ridge. A retrospective clinical study. Oral Maxillofac Surg. 2016;20(2):115–22 [Epub ahead of print]. Buser D, Dula K, Hirt HP, Schenk RK. Lateral ridge augmentation using autografts and barrier membranes: clinical study with 40 partially edentulous patients. J Oral Maxill...

Conclusions : Autogenous bone grafts in oral impla...

The results of the clinical study proves the reliability and low comorbidity of autologous bone grafts in preprosthetic alveolar ridge reconstructions prior to implant insertion. The high graft success rate (95.6%) and the low early implant failure rate (0.38%) in a surveillance of all patients treated in three following years with this technique showing no exclusion and no dropout of any case for...

Discussion : Autogenous bone grafts in oral implan...

Data on risk factors based on the original examination and documentation are difficult to assess the adverse effects of variable factors on the surgical prognosis because of the multifactorial genesis of surgical complications [73]. Factors such as gender, age, or smoking habit could be associated with postoperative complications after two-stage dentoalveolar reconstruction with autologous bone gr...

Discussion : Autogenous bone grafts in oral implan...

The results of the present study have to take into account the absence of a control group with patients undergoing bone augmentation procedures with bone substitutes (allogen, alloplastic, exogen). Without a comparative group of grafting surgeries using alternative bone material, only limited statements can be made. However, the excellent surgical outcome of autologous surgical methods providing ...

Discussion : Autogenous bone grafts in oral implan...

The use of autologous bone in this study has shown excellent graft survival and success rate (95.6%). This is equal to the results from the studies on implants inserted in reconstructed sites [6, 8, 24]. The early implant survival rate of 99.7% found in the present material is very high comparable to that in the previous systematic reviews after staged horizontal ridge augmentation [9, 10, 22, 62,...

Discussion : Autogenous bone grafts in oral implan...

Of the sinus floor elevations performed in this study, 84.8% were defined absolutely successful. Only two of our 72 patients having sinus lift operations could not finally be treated with dental implants. These results are comparable to other studies considering the sinus graft to be a safe treatment modality with few complications [6, 8, 51,52,53]. Raghoebar et al. reported incidences of sinus co...

Discussion : Autogenous bone grafts in oral implan...

Postoperative morbidity after mandibular bone harvesting procedures was reported to be mainly related to temporary or permanent neural disturbances involving the inferior alveolar nerve and its branches [19]. In this study, only the incidence of the temporary hypoesthesia of the mandibular and lingual nerve after harvesting from the retromolar area could be detected. It was 10.4 and 2.8%, respecti...

Discussion : Autogenous bone grafts in oral implan...

Systematic reviews have failed to find evidence that one particular grafting technique is superior to others [10]. Intraoral bone grafts from the mandibular symphysis, mandibular ramus, and maxillary tuberosity provide a good treatment modality for ridge augmentation, and the amount of bone available for harvesting is sufficient for defects up to the width of three teeth [42]. Harvesting of retrom...

Discussion : Autogenous bone grafts in oral implan...

Several grafting procedures have been described to create sufficient volume of bone for implant placement [8, 9]. Autologous bone grafts can be harvested by an intraoral approach (mandibular ramus, mandibular symphysis, zygomatic buttress) or from distant sites (iliac crest, calvaria, and etc.) [17, 36, 37]. However, bone harvesting potentially causes donor site morbidity which is a major issue fo...

Results : Autogenous bone grafts in oral implantol...

The average healing period until implant placement after bone harvesting was 4.53 months. Initially, 546 implants in 279 patients were planned. After the healing period, it was possible to place 525 implants in 436 successfully augmented areas in 259 patients. Three hundred implants were inserted in the maxilla and 225 in the mandible. The remaining 21 implants planned for 20 patients could not b...

Results : Autogenous bone grafts in oral implantol...

Regarding intraoperative complications, all sinus membrane perforations were covered with a resorbable collagen membrane (Bio-Gide®, Geistlich Biomaterials, Baden-Baden, Germany) which applied as sealant to overlap the site of perforation prior to insertion of the graft material. These patients were advised to avoid physical stress, blowing their noses, or sneezing for a period of 3 weeks, and n...

Results : Autogenous bone grafts in oral implantol...

No permanent damage to any trigeminal nerves was evident in any of our entire cohort. All cases of postoperative hypoesthesia of the mental, lingual, or infraorbital nerve were just a temporary nature. At the time of implant surgery, none of these patients reported any persisting neural disturbances (Fig. 4). In eleven patients, hypoesthesia of the mental area was mentioned, and three of them al...

Results : Autogenous bone grafts in oral implantol...

Thirty-eight patients underwent a total of 116 augmentation procedures harvesting from the iliac crest. In 20 patients, a bone graft augmentation of the maxilla and the mandible in combination with bilateral sinus floor augmentations was performed. Eighteen patients had augmentations only in the maxilla, involving bone grafting and sinus lift elevations. Totally, 76 sinus lifts with bone material ...

Results : Autogenous bone grafts in oral implantol...

In six patients, a partial graft resorption was detected at the time of implantation and an additional simultaneous augmentation with bone chips harvested with the Safescraper device (C.G.M. S.p.A., Divisione Medicale META, Italy) was then necessary in order to ensure the osseointegration of the implants. Two out of these six cases had grafts from the crista zygomatico-alveolaris, two from the ram...

Results : Autogenous bone grafts in oral implantol...

A total of 112 sinus floor elevations were performed. In all of the cases, implants were inserted in a two-stage procedure. The donor site for harvesting the bone for the sinus elevations was in 76 procedures in the iliac crest area, and in 36 procedures, the bone was harvested with a bone scraper device from the lateral sinus wall at the site of sinus lifting. The distribution and number of tran...

Results : Autogenous bone grafts in oral implantol...

Two hundred seventy-nine patients—250 men and 29 women—underwent 456 augmentation procedures involving autologous bone grafts prior to implant placement. The patients ranged in age from 18.5 to 71.5 years (average 43.1 years) at the moment of augmentation surgery. Of those patients, 162 (58.1%) were younger than 40 years of age and 117 (41.9%) were older than 40 years of age. Caries or pe...

Methods : Autogenous bone grafts in oral implantol...

Early and late implant loss was documented in this study, defining the clinical success of osseointegration. Early implant failures were assessed before the acquisition of osseointegration, i.e., before the placement of prosthodontic restorations. Early implant failure could occur from the time of placement, during the healing phase and before abutment connection. The implant inserted after re-aug...

Methods : Autogenous bone grafts in oral implantol...

Medical history of patient Age of patient at the time of bone harvesting and augmentation History of periodontal disease Smoking habits Donor site Jaw area and dental situation of the recipient site Intraoperative complications Postoperative complications after augmentation Management of complications Bone graft stability and clinical resorption prior to implant placement Complications a...

Methods : Autogenous bone grafts in oral implantol...

In addition to the bone already gained with the bone scraper device from the sinus wall during the antrostomy, bone was harvested with the same device from the maxillary buccal buttress, if more volume was needed. By taking this approach, the collection of enough bone for the augmentation of at least two implantation sites was feasible with a mean surgical time of 5 to 10 min for harvesting. In c...

Methods : Autogenous bone grafts in oral implantol...

Grafting from the iliac crest was always performed under general anesthesia in a two-team approach. The iliac crest was exposed and autogenous grafts from the anterosuperior inner edge of the iliac wing were harvested with an oscillating saw and/or a chisel, keeping a safe distance of around 2 cm from the anterosuperior iliac spine. After harvesting the bone grafts, the corticocancellous bone blo...

Methods : Autogenous bone grafts in oral implantol...

A standardized two-stage surgical protocol was used, and all sites were treated in a similar fashion. In the first intervention, a bone block harvested from the donor site was fixed with osteosynthesis titanium screws to the recipient site as an onlay graft to achieve a horizontal and/or vertical enlargement of the alveolar ridge. Placement of the bone graft was always guided by an augmentation te...

Methods : Autogenous bone grafts in oral implantol...

For this retrospective cohort study, we reviewed the records of all patients without exclusion criteria who were referred to the department of oral and plastic maxillofacial surgery at the military hospital of Ulm, Germany, between January 2009 and December 2011 for alveolar ridge augmentations prior to implant insertions using autologous bone grafts harvested from different donor sites and unilat...

Background : Autogenous bone grafts in oral implan...

In our military outpatient center exclusively, autologous bone transplantations harvested from different donor sites were used intraorally (crista zygomatico-alveolaris, ramus mandible, symphysis mandible, anterior sinus wall) and extraorally (iliac crest) to reconstruct severe horizontal and/or vertical alveolar ridge atrophy prior to implant placement. The aim of this study was to assess the cli...

Background : Autogenous bone grafts in oral implan...

Although the iliac crest is most often used in jaw reconstruction, a significant bone resorption has been mentioned [12]. This disadvantage, and the fact that dental implants do not always require a large amount of bone, has increased the use of autologous block bone grafts from intraoral sources [13]. Bone grafts from intraoral donor sites offer several benefits like surgical accessibility, proxi...

Background : Autogenous bone grafts in oral implan...

Oral implantation has a significant role in the rehabilitation of patients. Bone reconstruction techniques have been advanced in order to optimize the esthetic and functional outcome. However, the restoration of the oral function of atrophic alveolar crests still remains a challenge in oral implantology. Bone augmentation procedures are often indicated to allow implant placement in an optimal thre...

Abstract : Autogenous bone grafts in oral implanto...

This review demonstrates the predictability of autologous bone material in alveolar ridge reconstructions prior to implant insertion, independent from donor and recipient site including even autologous bone chips for sinus elevation. Due to the low harvesting morbidity of autologous bone grafts, the clinical results of our study indicate that autologous bone grafts still remain the “gold standar...

Abstract : Autogenous bone grafts in oral implanto...

This study assessed the clinical outcomes of graft success rate and early implant survival rate after preprosthetic alveolar ridge reconstruction with autologous bone grafts. A consecutive retrospective study was conducted on all patients who were treated at the military outpatient clinic of the Department of Oral and Plastic Maxillofacial Surgery at the military hospital in Ulm (Germany) in the ...

Fig. 5. Histomorphometric analysis of the same sam...

ple. a Ground section stained with Levai-Laczkó. b Tissue identification of the ROI. c Closer view a bone and CCXBB. d Closer view of b Fig. 5. Histomorphometric analysis of the same sample. a Ground section stained with Levai-Laczkó. b Tissue identification of the ROI. c Closer view a arrow pointing a cement line between new mineralized bone and CCXBB. d Closer view of b

Fig. 4. Histological samples. a CCXBB control with...

Fig. 4. Histological samples. a CCXBB control without implantation. b Histologic samples with acute inflammatory infiltration. c Histologic sample with limited remaining CCXBB and large bone ingrowth Fig. 4. Histological samples. a CCXBB control without implantation. b Histologic samples with acute inflammatory infiltration. c Histologic sample with limited remaining CCXBB and large bone ingr...

Fig. 3. Re-entry procedure of patient in Fig. 1. ...

Fig. 3. Re-entry procedure of patient in Fig. 1. a Buccal aspect of the augmented region. b Horizontal bone augmentation. c Screws and pins removal and bone trephine sampling. d Implants placement and buccal bone width from the implant shoulder. e Primary flap closure. f Implants submerged healing Fig. 3. Re-entry procedure of patient in Fig. 1. a Buccal aspect of the augmented region. b Ho...

Fig. 2. Lateral bone augmentation of the alveolar ...

Fig. 2. Lateral bone augmentation of the alveolar crest (a) atrophic ridge. b Perforations and adaptation of the cortical layer. c Shaping, pre-wetting and fixation of CCXBB with titanium screws. d Horizontal contour and peripheral gap between CCXBB and bone layer. e Outlying DBBM filling. f CM stabilized with pins Fig. 2. Lateral bone augmentation of the alveolar crest (a) atrophic ridge. b ...

Fig. 1. Study chart and follow-up visits : Histomo...

Fig. 1. Study chart and follow-up visits Fig. 1. Study chart and follow-up visits

Table 4 Implant loss and tissue characteristics : ...

Differentiated tissues Implant lost (Yes/no) Mean SD Percentage SD (%) ...

Table 3 Immunohistochemical markers proportions (i...

Patient TRAP (%) OPN (%) ALP (%) OSC (%) 1 ...

Table 2 Quantitative histological analysis : Histo...

Tissue type Mean Standard deviation Median CI 95% Mineralized bone ...

Table 1 Clinical and histomorphometry assessments ...

Patient Soft tissue dehiscence Mineralized bone (%) CCXBB (%) Bone marrow (%) Connect...

About this article : Histomorphometric and immunoh...

Ortiz-Vigón, A., Martinez-Villa, S., Suarez, I. et al. Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement. Int J Implant Dent 3, 24 (2017). https://doi.org/10.1186/s40729-017-0087-1 Download citation Received: 21 March 2017 Accepted: 12 June 2017 Published: 21 Ju...

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Author information : Histomorphometric and immunoh...

ETEP Research Group, Facultad de Odontología, Universidad Complutense de Madrid, Plaza Ramón y Cajal, 28040, Madrid, Spain Alberto Ortiz-Vigón, Sergio Martinez-Villa, Iñaki Suarez, Fabio Vignoletti & Mariano Sanz You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar ...

Acknowledgements : Histomorphometric and immunohis...

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Acknowledgements : Histomorphometric and immunohis...

We wish to acknowledge the dedication and scientific advise of Prof. Dr. Tord Berglundh on the histological analysis as well as the diligent work in processing the histological samples to Estela Maldonado for the immunohistochemistry and Asal Shikhan and Fernando Muñoz for the histomorphometry. The work of Esperanza Gross on the statistical analysis is highly acknowledged. This study was partial...

References : Histomorphometric and immunohistochem...

Patti A, Gennari L, Merlotti D, Dotta F, Nuti R. Endocrine actions of osteocalcin. Int J Endocrinol. 2013;2013:846480. Schwarz F, Herten M, Sager M, Wieland M, Dard M, Becker J. Histological and immunohistochemical analysis of initial and early osseous integration at chemically modified and conventional SLA titanium implants: preliminary results of a pilot study in dogs. Clin Oral Implants Res. 2...

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Araujo MG, Linder E, Lindhe J. Bio-Oss collagen in the buccal gap at immediate implants: a 6-month study in the dog. Clin Oral Implants Res. 2011;22:1–8. Chiapasco M, Colletti G, Coggiola A, Di Martino G, Anello T, Romeo E. Clinical outcome of the use of fresh frozen allogeneic bone grafts for the reconstruction of severely resorbed alveolar ridges: preliminary results of a prospective study. I...

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Jeno L, Geza L. A simple differential staining method for semi-thin sections of ossifying cartilage and bone tissues embedded in epoxy resin. Mikroskopie. 1975;31:1–4. Dias RR, Sehn FP, de Santana Santos T, Silva ER, Chaushu G, Xavier SP. Corticocancellous fresh-frozen allograft bone blocks for augmenting atrophied posterior mandibles in humans. Clin Oral Implants Res. 2016;27:39–46. Nissan ...

References : Histomorphometric and immunohistochem...

Cremonini CC, Dumas M, Pannuti C, Lima LA, Cavalcanti MG. Assessment of the availability of bone volume for grafting in the donor retromolar region using computed tomography: a pilot study. Int J Oral Maxillofac Implants. 2010;25:374–8. Nkenke E, Weisbach V, Winckler E, Kessler P, Schultze-Mosgau S, Wiltfang J, et al. Morbidity of harvesting of bone grafts from the iliac crest for preprosthetic...

References : Histomorphometric and immunohistochem...

Sanz M, Vignoletti F. Key aspects on the use of bone substitutes for bone regeneration of edentulous ridges. Dent Mater. 2015;31:640–7. Benic GI, Hammerle CH. Horizontal bone augmentation by means of guided bone regeneration. Periodontology. 2014;66:13–40. Beretta M, Cicciu M, Poli PP, Rancitelli D, Bassi G, Grossi GB, et al. A Retrospective Evaluation of 192 Implants Placed in Augmented Bon...

Abbreviations : Histomorphometric and immunohistoc...

Alkaline phosphatase Cone beam computed tomography Collagen containing xenogeneic bone block Native collagen membrane Deproteinized bovine bone mineral Etiology and Therapy of Periodontal Diseases Osteopontin Osteocalcine Tartrate-resistant acid phosphatase

Conclusions : Histomorphometric and immunohistoche...

Within the limitations of this clinical study, we may conclude that the use of CCXBB in combination with DBBM particles and a native bilayer collagen membrane for staged lateral bone augmentation in severe atrophic alveolar crests achieved significant horizontal crestal width allowing for staged implant placement in most of the patients. Histological analysis and implant survival records indicate ...

Discussion : Histomorphometric and immunohistochem...

The immune-histochemical results reported expression of osteopontin mainly at the border between mineralized vital bone (MVB) with CCXBB, what coincides with findings from previous reports [38,39,40]. Alkaline phosphatase (ALP) is considered as an early osteoblast differentiation marker [41]. ALP-positive cells were detectable, in all specimens on the periphery of MVB, associated to areas of new b...

Discussion : Histomorphometric and immunohistochem...

When correlating the clinical results and the histological outcomes, there was a positive association between the presence of soft tissue dehiscence with CCXBB exposure and a diminished amount of new mineralized bone (p = 0.06). This lower amount of new bone within the xenogeneic graft suggests a lack of full graft integration and diminished vascular supply, what may have caused the soft tissu...

Discussion : Histomorphometric and immunohistochem...

The purpose of this investigation was to evaluate histologically and immunohistochemically the behavior of CCXBB blocks when used for staged lateral bone augmentation in severe human horizontal residual bone defects. Six months after the regenerative intervention using the CCXBB blocks, the mean increase in bone width was 4.12 mm and hence, this outcome allowed for the placement of dental implant...

Results : Histomorphometric and immunohistochemica...

The results from the histomorphometric measurements are depicted in Table 2. Bone biopsies were composed by 21.37% (SD 7.36) of residual CCXBB, 26.90% (SD 12.21) of mineralized vital bone (MVB), 47.13% (SD 19.15) of non-mineralized tissue and 0.92% of DBBM (Fig. 5b). Biopsies from patients who lost their implants had a statistical significant lower amount of MVB (p = 0.01u) and a statistical...

Results : Histomorphometric and immunohistochemica...

Twenty-eight CCXBB blocks were placed in 15 patients that fulfilled the selection criteria (12 women and 3 men) with a mean age of 54.5 (SD 8.34). The detailed clinical and radiographical outcomes have been reported previously [21]. In brief, one patient experienced pain and soft tissue dehiscence leading to removal of the graft material 3 days after the regenerative procedure. Another patient r...

Methods : Histomorphometric and immunohistochemica...

For the immunohistochemical analysis, the semi-thin sections were incubated over night with primary antibodies at 4 °C (Santa Cruz Biotechnology Inc., Santa Cruz, Calif., USA). The antibody dilutions used were alkaline phosphatase (ALP) 1:100, osteopontin (OPN) 1:100, osteocalcin (OSC) 1:100, and tatrate resistant acid phosphatase (TRAP) 1:100. The obtained semi-thin sections were evaluated wit...

Methods : Histomorphometric and immunohistochemica...

Twenty-six weeks after the regenerative procedure the patient returned for the re-entry intervention for placement of dental implants. After raising full-thickness flaps, the augmented area was exposed and horizontal crestal width measurements were performed. Then, the surgeon evaluated the bone availability and if implant placement was considered possible, a core bone biopsy was harvested with th...

Methods : Histomorphometric and immunohistochemica...

CCXBB (Bio-Graft® Geistlich Pharma) is a bone substitute material in a natural block form. The dimensions of the Bio-Graft block are 10 mm in height, 10 mm in length and 5 mm in width. It consists of a natural cancellous bone structure of hydroxyapatite and endogenous collagen type I and III, equine origin and is a class III medical device according to the Medical Device Directive 93/42 EECs...

Methods : Histomorphometric and immunohistochemica...

The present manuscript reports the histological outcomes of a prospective single arm study evaluating the safety and clinical performance of CCXBB blocks when used as replacement bone grafts for lateral bone augmentation prior to staged implant placement. The results of the clinical and radiographic outcomes have been reported in a previous publication [21]. For correlation of the histological wit...

Background : Histomorphometric and immunohistochem...

Different techniques and grafting materials have been used for the horizontal reconstruction of deficient alveolar processes before implant placement, resulting in different degrees of predictability and clinical outcomes [1]. Among the grafting materials, particulated xenogeneic materials have been extensively studied in both experimental and clinical studies and when combined with porcine-derive...

Abstract : Histomorphometric and immunohistochemic...

The osteoconductive properties of collagen containing xenogeneic bone blocks (CCXBB) remain unclear. The aim of this prospective single-arm clinical study was to assess the histological outcomes of CCXBB blocks used as bone replacement grafts for lateral bone augmentation procedures. In 15 patients with severe horizontal alveolar ridge resorption, lateral augmentation procedures were performed us...

About this article : In vitro comparison of two ti...

Dhaliwal, J.S., Marulanda, J., Li, J. et al. In vitro comparison of two titanium dental implant surface treatments: 3M™ESPE™ MDIs versus Ankylos®. Int J Implant Dent 3, 27 (2017). https://doi.org/10.1186/s40729-017-0083-5 Download citation Received: 19 January 2017 Accepted: 22 May 2017 Published: 27 June 2017 DOI: https://doi.org/10.1186/s40729-017-0083-5

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Author information : In vitro comparison of two ti...

Faculty of Dentistry, McGill University, Montreal, Quebec, Canada Jagjit Singh Dhaliwal, Juliana Marulanda, Sharifa Alebrahim, Jocelyne Sheila Feine & Monzur Murshed PAPRSB, Institute of Health Sciences, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong, BE1410, Brunei Darussalam Jagjit Singh Dhaliwal Faculty of Medicine, McGill University, Montreal, Quebec, Canada Jingjing Li & ...

Acknowledgements : In vitro comparison of two tita...

The authors would like to thank Prof. Georgios Romanos, School of Dental Medicine, Dept. of Periodontology, Stony Brook University, Stony Brook, NY, USA, for his contribution to the study. We would also like to thank 3M ESPE and Dentsply Friadent for providing the implant disks. This work is a part of the thesis submitted by JD for attaining a PhD degree at the Faculty of Dentistry, McGill Univers...

References : In vitro comparison of two titanium d...

Wennerberg A, Albrektsson T. Effects of titanium surface topography on bone integration: a systematic review. Clin Oral Implants Res. 2009;20 Suppl 4:172–84. Download references

References : In vitro comparison of two titanium d...

Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol. 1983;96(1):191–8. Novaes Jr AB, de Souza SL, de Barros RR, Pereira KK, Iezzi G, Piattelli A. Influence of implant surfaces on osseointegration. Braz Dent J. 2010;21(6):471–81. MacDonald DE, Markovic B, Allen M, Som...

References : In vitro comparison of two titanium d...

Buser D, Nydegger T, Oxland T, Cochran DL, Schenk RK, Hirt HP, et al. Interface shear strength of titanium implants with a sandblasted and acid-etched surface: a biomechanical study in the maxilla of miniature pigs. J Biomed Mater Res. 1999;45(2):75–83. Li D, Ferguson SJ, Beutler T, Cochran DL, Sittig C, Hirt HP, et al. Biomechanical comparison of the sandblasted and acid-etched and the machine...

References : In vitro comparison of two titanium d...

Griffitts TM, Collins CP, Collins PC. Mini dental implants: an adjunct for retention, stability, and comfort for the edentulous patient. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005;100(5):e81–4. Cooper LF, Zhou Y, Takebe J, Guo J, Abron A, Holmen A, et al. Fluoride modification effects on osteoblast behavior and bone formation at TiO2 grit-blasted c.p. titanium endosseous implants. B...

References : In vitro comparison of two titanium d...

Branemark PI, Hansson BO, Adell R, Breine U, Lindstrom J, Hallen O, et al. Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scand J Plast Reconstr Surg Suppl. 1977;16:1–132. Bulard RA, Vance JB. Multi-clinic evaluation using mini-dental implants for long-term denture stabilization: a preliminary biometric evaluation. Compend Contin Educ Dent. 20...

Conclusions : In vitro comparison of two titanium ...

Our results demonstrate that both implant surfaces are conducive for osteoblastic cell attachment, proliferation, and mineralization. However, 3M™ESPE™ MDI surface shows more pronounced effects on cell proliferation, which may in turn facilitate better osseointegration by enhancing ECM mineralization. Our ongoing research will provide further information on how implant surfaces may affect cell...

Discussion : In vitro comparison of two titanium d...

ALPL is a late osteogenic marker, which is essential for normal bone mineralization. ALPL-deficient osteoblasts fail to mineralize in culture. Considering that there was no significant difference in the relative ALPL activity in cells grown on two surfaces, it is unlikely that the surface property of the disks affected cell differentiation. This observation does not support the findings of Davies ...

Discussion : In vitro comparison of two titanium d...

MC3T3-E1 cells have been extensively used in numerous cell culture experiments as a model for osteoblasts [36]. Under differentiating conditions, e.g., in the presence of ascorbic acid and β-glycerol phosphate, these cells upregulate the osteogenic markers and, more importantly, promote the deposition of calcium phosphate minerals within and around the collagen-rich extracellular matrix (ECM). In...

Discussion : In vitro comparison of two titanium d...

In the current study, we used an in vitro cell culture system to evaluate the biocompatibility of two implant materials with different surface topography. Our objective was to establish the osseointegration potential of MDIs versus an established regular implant. Disks prepared from the implant material were coated with gelatin to grow cells, and proliferation and osteogenic differentiation parame...

Results : In vitro comparison of two titanium dent...

Pre-osteoblastic MC3T3-E1 cells were plated on each implant disk (40,000 cells/disk) and were differentiated with mineralization medium for 12 days. Quantification of cells after nuclear staining by H33258 revealed an increased number of cells on the 3M™ESPE™ MDI disks (Fig. 5a). Measurement of cell viability by the reduction of Alamar blue® after 3 days of culture of MC3T3-E1 cells furthe...

Results : In vitro comparison of two titanium dent...

The variable sizes of the implant disks obtained from two different manufacturers demanded an innovative culture system to ensure equal surface areas on both disks for the cell culture experiments. We achieved this by attaching constant diameter (5 mm) plastic cylinders to the disk surface. Disks were sterilized with absolute alcohol, and polystyrene cloning cylinders (Sigma) were attached onto t...

Methods : In vitro comparison of two titanium dent...

While performing the experiments, JM (first co-author) was not aware of the sources/manufacturers of the disks, which were identified by their size (small and large) only. At the end of the analyses, each disk’s manufacturer was revealed to her by JSD (first co-author).

Methods : In vitro comparison of two titanium dent...

Protein samples from the transfected cells were prepared in 1× SDS gel-loading buffer (Laemmli buffer) without adding β-mercaptoethanol and quantified using the Pierce™ Coomassie Plus Assay kit (Thermo Scientific, Rockford, IL, USA). Without heat denaturation, equal amount of protein samples (50 μg) were loaded on a 10% SDS-polyacrylamide gel. After electrophoresis, the gel was incubated in N...

Methods : In vitro comparison of two titanium dent...

Titanium disks made up with the same materials and surface characteristics as those with the original implants were obtained from the respective manufacturers. Two types of disks were used; the small disks represented 3M™ESPE™ MDI implants, while the large disks represented Ankylos®, Dentsply Friadent implants. A total of 10 disks of each brand were used for the study. Disks were sterilized ...

Background : In vitro comparison of two titanium d...

Despite the advantages of the MDI, evidence on their potential for osseointegration and long-term success is lacking. [15,16,17,18]. Newer implant systems entering the market must be studied first in vitro and then in vivo with animal models followed by human studies to demonstrate their osseointegration capability. Modifications of implant surface properties have been shown to have a positive in...

Background : In vitro comparison of two titanium d...

Prosthetic devices are often used as surrogates for missing skeletal and dental elements. These devices are in close contact with the surrounding tissues, and their functionality and stability are critically dependent on the successful integration within the tissue’s extracellular matrix (ECM). The surface of the implanted device directly interacts with cell and extracellular milieu and influenc...

Abstract : In vitro comparison of two titanium den...

An ideal implant should have a surface that is conducive to osseointegration. In vitro cell culture studies using disks made of same materials and surface as of implants may provide useful information on the events occurring at the implant-tissue interface. In the current study, we tested the hypothesis that there is no difference in the proliferation and differentiation capacities of osteoblastic...

Fig. 3. Forest plot of quality of life. A statisti...

Fig. 3. Forest plot of quality of life. A statistically significant improvement was observed in the quality of life parameter with mini implants than standard implants Fig. 3. Forest plot of quality of life. A statistically significant improvement was observed in the quality of life parameter with mini implants than standard implants

Fig. 2. Risk of bias of the included studies : Com...

Fig. 2. Risk of bias of the included studies Fig. 2. Risk of bias of the included studies

Fig. 1. PRISMA flow diagram : Comparison of patien...

Fig. 1. PRISMA flow diagram Fig. 1. PRISMA flow diagram

Table 2 Grading the strength of evidence : Compari...

Comparison of parameters between standard and mini-implants for implant-supported overdenture: Outcomes Parameter values No. of participants (studies) ...

Table 1 List of included studies : Comparison of p...

Author Participant Intervention Comparator Outcome De Souza 2015[8] ...

About this article : Comparison of patient satisfa...

Sivaramakrishnan, G., Sridharan, K. Comparison of patient satisfaction with mini-implant versus standard diameter implant overdentures: a systematic review and meta-analysis of randomized controlled trials. Int J Implant Dent 3, 29 (2017). https://doi.org/10.1186/s40729-017-0092-4 Download citation Received: 12 April 2017 Accepted: 22 June 2017 Published: 01 July 2017 DOI...

Rights and permissions : Comparison of patient sat...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Comparison of patient satisf...

Gowri Sivaramakrishnan and Kannan Sridharan declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Comparison of patient satisfa...

Department of Oral Health, College of Medicine, Nursing and Health Sciences, Fiji National University, Brown Street, Suva, Fiji Gowri Sivaramakrishnan Department of Pharmacology, Fiji National University, Extension Street, Suva, Fiji Kannan Sridharan You can also search for this author in PubMed Google Scholar You can also search for this author in ...

Acknowledgements : Comparison of patient satisfact...

We acknowledge Cochrane reviews for utilizing RevMan software for generating the pooled results and Forest plots. No source of funding.

References : Comparison of patient satisfaction wi...

Download references

References : Comparison of patient satisfaction wi...

Kumari P, Verma M, Sainia V, Gupta A, Gupta R, Gill S. Mini-implants, mega solutions: a case series. J Prosthodont. 2015. doi:10.1111/jopr.12382. Jackson BJ. Fixed partial denture treatment with mini dental implants. J Oral Implantol. 2014;40:744–50. Flanagan D, Mascolo A. The mini dental implant in fixed and removable prosthetics: a review. J Oral Implantol. 2011;37 Spec No:123–32. doi:10.1...

Conclusion : Comparison of patient satisfaction wi...

However, considering the results obtained from available evidence, mini-implants tend to provide good patient satisfaction compared to standard diameter implants when used for implant-supported overdentures. The results of this meta-analysis should be interpreted keeping in the mind the limited availability of data to be included. This paper would serve as a basis for future research comparing min...

Discussion : Comparison of patient satisfaction wi...

This study is an attempt to identify patient satisfaction with mini-implant overdentures compared to standard diameter implant-supported overdentures in completely edentulous patients. Implant-supported overdentures have been reported to offer many advantages like decreased bone resorption, reduced prosthesis movement, better esthetics, better occlusion and tooth positioning, improved occlusal loa...

Results : Comparison of patient satisfaction with ...

A total of 183 articles were identified using the search strategy. Screening of these papers yielded four studies comparing mini-implant-retained overdentures and standard diameter implant overdentures and were found eligible to be included in the systematic review [8,9,10,11]. Two studies [8, 11] comparing patient satisfaction between the groups were included for the meta-analysis. The PRISMA flo...

Materials and methodology : Comparison of patient ...

The protocol for this review was registered with International prospective register of systematic reviews (PROSPERO) with the registration number CRD42016043075. The review protocol can be accessed at https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016043075. A through literature search was conducted and was completed on 9 July 2016. The primary database used was MEDLINE (via PubMed...

Review : Comparison of patient satisfaction with m...

Implants have been considered to improve treatment outcomes of completely edentulous patients with anatomical challenges compromising the retention and stability. The root form dental implants which are 3–5 mm in diameter are considered standard diameter implants while less than 3 mm diameter implants are termed mini-implants [1]. Initially, mini-implants were used as a temporary measure, with...

Abstract : Comparison of patient satisfaction with...

Mini-implants have certain advantages over standard size implants which are being tested in various randomized controlled trials. This systematic review and meta-analysis aims to compare conventional implant overdentures to mini-implant-retained overdentures as regards to patient satisfaction. Electronic databases were searched for eligible studies data required were extracted. The extracted data ...

Fig. 10. Patient 1—post-operative evaluation of ...

Fig. 10. Patient 1—post-operative evaluation of placement accuracy of the implants in the mandible. Green is the planned position; blue is the actual position Fig. 10. Patient 1—post-operative evaluation of placement accuracy of the implants in the mandible. Green is the planned position; blue is the actual position

Fig. 9. Patient 1—prosthodontic end result 5 mo...

Fig. 9. Patient 1—prosthodontic end result 5 months after implant placement Fig. 9. Patient 1—prosthodontic end result 5 months after implant placement

Fig. 8. Patient 2—intra-oral situation during or...

Fig. 8. Patient 2—intra-oral situation during orthodontic treatment at the age of 14. A temporary crown with bracket is fixed on the dental implant. Eight months after start of orthodontic treatment, the 34 is already close to the planned end position Fig. 8. Patient 2—intra-oral situation during orthodontic treatment at the age of 14. A temporary crown with bracket is fixed on the dental...

Fig. 7. Patient 2—post-operative orthopantomogra...

Fig. 7. Patient 2—post-operative orthopantomogram (OPT) at age of 13. Situation 10 months after implant placement. Three months after starting the orthodontic treatment, the 34 is already erected Fig. 7. Patient 2—post-operative orthopantomogram (OPT) at age of 13. Situation 10 months after implant placement. Three months after starting the orthodontic treatment, the 34 is already erect...

Fig. 6. Patient 1—post-operative orthopantomogra...

Fig. 6. Patient 1—post-operative orthopantomogram (OPT) at age of 18 Fig. 6. Patient 1—post-operative orthopantomogram (OPT) at age of 18

Fig. 5. a Drilling templates of patient 1. Printed...

Fig. 5. he maxilla (left) and mandible (right) with drilling template and metal drilling inserts (Nobel biocare). b Drilling template for the mandible of patient 1. c Implant placement of patient 1. Dental implant placement in the mandible using the virtual developed tooth-supported templates and metal drilling inserts Fig. 5. a Drilling templates of patient 1. Printed model of the maxilla (l...

Fig. 4. a Patient 1—virtual set-up of the ultima...

Fig. 4. t goal. b Patient 2—virtual set-up of the ultimate implant position. One short dental implant was planned in region 35, based on the location of the mandibular nerve (orange), the impacted 34 (pink) and the bone quality and volume. c Patient 2—virtual set-up of the ultimate prosthetic treatment goal Fig. 4. a Patient 1—virtual set-up of the ultimate treatment goal. b Patient 2...

Fig. 3. a Patient 1—detailed 3D model of the com...

Fig. 3. e CBCT and intra-oral scan at age of 18. b Patient 2—detailed 3D model of the combined data from the CBCT and intra-oral scan at age of 12 Fig. 3. a Patient 1—detailed 3D model of the combined data from the CBCT and intra-oral scan at age of 18. b Patient 2—detailed 3D model of the combined data from the CBCT and intra-oral scan at age of 12

Fig. 2. a Patient 2—pre-implant orthopantomogram...

Fig. 2. uation before start of orthodontic and implant treatment. Eleven permanent teeth (including 2 third molars) were congenitally missing and the 34 is impacted. To erect the 34, orthodontic treatment was desired. Due to the lack of stable anchorages in the third quadrant, it was decided to place one implant at tooth region 35 for orthodontic anchorage and future prosthetics. Due to very lim...

Fig. 1. a Patient 1—orthopantomogram (OPT) at ag...

Fig. 1. osed deciduous teeth 55, 54, 65, 74, 75, 84, and 85 and start of orthodontic treatment. Eleven permanent teeth (including 4 third molars) were congenitally missing. b Patient 1—post-orthodontic situation at age of 16. The top of the mandibular processus alveolaris is small (upper). The interdental space at location of the second premolars in the maxilla is 7 and 14 mm at location of t...

Table 1 Accuracy data: Euclidian distances (ED, mm...

Patient Location implant (tooth nr) Shoulder Tip Axis X Y Z ED (mm) ...

About this article : Three-dimensional computer-gu...

Filius, M.A.P., Kraeima, J., Vissink, A. et al. Three-dimensional computer-guided implant placement in oligodontia. Int J Implant Dent 3, 30 (2017). https://doi.org/10.1186/s40729-017-0090-6 Download citation Received: 27 March 2017 Accepted: 22 June 2017 Published: 08 July 2017 DOI: https://doi.org/10.1186/s40729-017-0090-6

Rights and permissions : Three-dimensional compute...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Three-dimensional computer-g...

This is not applicable as this research was an evaluation of routine dental care. Not applicable. Author Marieke Filius, Joep Kraeima, Arjan Vissink, Krista Janssen, Gerry Raghoebar and Anita Visser state that there are no conflicts of interest. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Three-dimensional computer-gu...

Correspondence to Anita Visser.

Author information : Three-dimensional computer-gu...

Department of Oral and Maxillofacial Surgery, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands Marieke A. P. Filius, Joep Kraeima, Arjan Vissink, Gerry M. Raghoebar & Anita Visser Department of Orthodontics, University of Groningen and University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands K...

Acknowledgements : Three-dimensional computer-guid...

The authors like to sincerely thank all co-workers from the Department of Orthodontics, University Center Groningen, The Netherlands, for the potent collaboration during the treatment process. We also kindly thank native English speaker Jadzia Siemienski for critically reading our manuscript and making suggestions to improve the English. This research did not receive any specific grant from fund...

References : Three-dimensional computer-guided imp...

Schalk-van der Weide Y, Beemer FA, Faber JA, Bosman F. Symptomatology of patients with oligodontia. J Oral Rehabil. 1994;21:247–61. Filius MA, Cune MS, Raghoebar GM, Vissink A, Visser A. Prosthetic treatment outcome in patients with severe hypodontia: a systematic review. J Oral Rehabil. 2016;43:373–87. Shen P, Zhao J, Fan L, et al. Accuracy evaluation of computer-designed surgical guide tem...

Abbreviations : Three-dimensional computer-guided ...

(Cone beam) computer tomography Two-dimensional Three-dimensional Euclidian distances Orthopantomogram

Conclusion : Three-dimensional computer-guided imp...

This technical advanced article introduces a fully digitalized workflow for implant planning in complex oligodontia cases. The application of computer-designed surgical templates enables predictable implant placement in oligodontia, where bone quantity and limited interdental spaces can be challenging for implant placement. The stepwise approach described in this technical advanced article provide...

Discussion : Three-dimensional computer-guided imp...

This technical advanced article illustrated the benefit of a full three-dimensional virtual workflow to guide implant placement in oligodontia cases as well as that implants can be reliably placed at the planned positions with the technique proposed. The described full three-dimensional virtual workflow has several advantages. First, the surgeon is pre-operatively better informed about the requir...

Results : Three-dimensional computer-guided implan...

The surgical guides fitted well and facilitated implant placement. All implants were placed in the native bone. No dehiscences of the implant surface occurred. Post-operative orthopantomograms (OPT) of patients 1 and 2 are shown in Figs. 6 and 7. In patient 1, six implants were placed (NobelParallel Conical Connection implants, Nobel Biocare Holding AG, Zürich-Flughafen, Switzerland; Length 8.5...

Patient and methods : Three-dimensional computer-g...

After raising a mucoperiostal flap, the dental implants were placed using the virtual developed tooth-supported drilling templates using metal inserts (Fig. 5c). It was checked whether no dehiscences of the implant surface were present.

Patient and methods : Three-dimensional computer-g...

A CBCT (ICat, Image Sciences International, Hatfield, UK; 576 slices, voxel size 0.3 mm, FOV: 11 × 16 cm) was made of two oligodontia patients (for patient details, see Figs. 1 and 2) for implant planning. Detailed patient information was obtained with regard to the nerve position and bone quality and quantity. In addition, a digital intra-oral scan was made to get a detailed 3D image of t...

Introduction : Three-dimensional computer-guided i...

Oligodontia is the congenital absence of six or more permanent teeth, excluding third molars [1]. The need for oral rehabilitation in patients with oligodontia is high as they often suffer from functional and aesthetic problems due to a high number of missing teeth. Implant-based prosthodontics seem to be favourable to improve oral function and aesthetics in oligodontia [2]. Implant treatment in ...

Abstract : Three-dimensional computer-guided impla...

The aim of computer-designed surgical templates is to attain higher precision and accuracy of implant placement, particularly for compromised cases. The purpose of this study is to show the benefit of a full three-dimensional virtual workflow to guide implant placement in oligodontia cases where treatment is challenging due compromised bone quantity and limited interdental spaces. A full, digita...

Fig. 6. Loading of implant off-axially : Peri-impl...

Fig. 6. Loading of implant off-axially Fig. 6. Loading of implant off-axially

Fig. 5. Loading of implant axially : Peri-implant

Fig. 5. Loading of implant axially Fig. 5. Loading of implant axially

Fig. 4. Installation of strain gauges on surfaces ...

Fig. 4. Installation of strain gauges on surfaces of epoxy resin adjacent to mini implants Fig. 4. Installation of strain gauges on surfaces of epoxy resin adjacent to mini implants

Fig. 3. Lava Ultimate Restorative crown on the two...

Fig. 3. Lava Ultimate Restorative crown on the two mini implants. Fig. 3. Lava Ultimate Restorative crown on the two mini implants.

Fig. 2. Metal crown supported on two mini implants...

Fig. 2. Metal crown supported on two mini implants Fig. 2. Metal crown supported on two mini implants

Fig. 1. a Standard, b short-wide, and c single-pie...

Fig. 1. Fig. 1. a Standard, b short-wide, and c single-piece mini implants

Table 5 Descriptive statistics and results of comp...

Crown Implant type Axial Off-axial P-value Mean SD ...

Table 4 Descriptive statistics and results of comp...

Axial Off-axial P value Mean SD Mean SD ...

Table 3 Descriptive statistics and results of comp...

Lava Ultimate crowns Metal crowns P value Mean SD Mean ...

Table 2 Descriptive statistics and results of comp...

Load Crown type Standard Short-wide Double mini P value ...

Table 1 Descriptive statistics and results of comp...

Standard Short-wide Double mini P value Mean SD Mean ...

About this article : Peri-implant biomechanical re...

Elfadaly, L.S., Khairallah, L.S. & Al Agroudy, M.A. Peri-implant biomechanical responses to standard, short-wide, and double mini implants replacing missing molar supporting hybrid ceramic or full-metal crowns under axial and off-axial loading: an in vitro study. Int J Implant Dent 3, 31 (2017). https://doi.org/10.1186/s40729-017-0094-2 Download citation Received: 14 Februar...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Peri-implant biomechanical r...

The authors L.S.Elfadaly, L.S.Kheirallah, and M.A.Alagroudy state that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Peri-implant biomechanical re...

Fixed Prosthodontics, Cairo University, Giza, Egypt Lamiaa Said Elfadaly, Lamiaa Sayed Khairallah & Mona Atteya Al Agroudy You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar LSE have...

References : Peri-implant biomechanical responses ...

Gracis S, Nicholls J, Chalupnik J, Yuodelis R. Shock-absorbing behavior of five restorative materials used on implants. Int J Prosthodont. 1990;4:282–91. Skalak R. Biomechanical considerations in osseointegrated prostheses. J Prosthet Dent. 1983;49:843–8. Misch C. Clinical biomechanics in implant dentistry, Contemporary Implant Dentistry. 3rd ed. 2008. p. 543–56. mosby,inc. Lundgren D, La...

References : Peri-implant biomechanical responses ...

Himmlova L, Dostalova T, Kacovsky A, Konvickova S. Influence of implant length and diameter on stress distribution: a finite element analysis. J Prosthet Dent. 2004;91(1):20–5. Shetty S, Puthukkat N, Bhat S, Shenoy K. Short implants: a new dimension in rehabilitation of atrophic maxilla and mandible. Journal of Interdisciplinary Dentistry. 2014;4(2):66. Misch C, Bidez M. Contemporary implant d...

References : Peri-implant biomechanical responses ...

Barbier L, Vander SJ, Krzesinski G, Schepers E, Van der Perre G. Finite element analysis of non-axial versus axial loading of oral implants in the mandible of the dog. J Oral Rehabil. 1998;25(11):847–58. Saime S, Murat C, Emine Y. The influence of functional forces on the biomechanics of implant-supported prostheses—a review. J Dent. 2002;30:271–82. Balshi T, Hernandez R, Pryszlak M, Range...

References : Peri-implant biomechanical responses ...

Mazor Z, Lorean A, Mijiritsky E, Levin L. Replacement of a molar with 2 narrow diameter dental implants. Implant Dent. 2012;21(1):36–8. Atwood D. Postextraction changes in the adult mandible as illustrated by micrographs of midsagittal sections and serial cephalometric roentgenograms. J Prosthet Dent. 1963;13:810–24. Felice P, Pellegrino G, Checchi L, Pistilli R, Esposito M. Vertical augment...

Conclusions : Peri-implant biomechanical responses...

Within the limitations of this in vitro study, the following conclusions could be drawn: Implant design, superstructure material, and load direction significantly affect peri-implant microstrains. The recorded compressive and tensile microstrains for the tested designs were within the physiologic loading range, as they did not exceed the compressive or tensile strength of the bone-implant interf...

Discussion : Peri-implant biomechanical responses ...

Regarding the effect of superstructure material on induced microstrains, generally, different implant designs supporting Lava Ultimate crowns showed higher mean microstrain values(1927.3 ± 1536.6 μɛ), in comparison with those supporting metal crowns (1313.7 ± 973.1 μɛ).Theoretical considerations [44, 45] and in vitro experiments [46,47,48,49] suggest that an occlusal material with ...

Discussion : Peri-implant biomechanical responses ...

Regarding the effect of direction of loading on induced microstrains, it was shown that changing the position of occlusal loading had a considerable effect on the amount of distribution of stresses where axial loading generated even distribution of load around the implant in comparison to off-axial loading where stresses were more pronounced in the area of load application. This might be due to th...

Discussion : Peri-implant biomechanical responses ...

Previous studies have shown that direct correlations exist between microstrain magnitudes and bone stability/instability conditions. This has been summarized by Frost, when bone is loaded below about 2000 microstrains, bone can easily repair what little microdamage occurs. Yet, when pathologic overloading occurs (over 4000 microstrains), stress and strain gradients exceed the physiologic tolerance...

Discussion : Peri-implant biomechanical responses ...

To replace a missing lower molar in compromised ridge, different treatment options were suggested, using either a standard size implant with surgical procedures, short-wide implant, or two mini implants. Concerning the use of mini implant, splinted multiple implants increase the surface area that interfaces with the bone to lessen the per square millimeters of force borne by the bone [11]. The imp...

Results : Peri-implant biomechanical responses to ...

Results revealed that standard implant showed the statistically significantly highest mean microstrain values (3362.4 ± 757.4 μɛ). Double mini implant showed statistically significantly lower mean microstrain values (801.6 ± 251.4 μɛ), while short-wide implant showed the statistically significantly lowest mean microstrain values (697.6 ± 79.7 μɛ), with a P value

Methods : Peri-implant biomechanical responses to ...

Data were presented as mean and standard deviation (SD) values. Data were explored for normality by checking data distribution and histograms, calculating mean and median values, and finally using Kolmogorov-Smirnov and Shapiro-Wilk tests of normality. Stress data showed non-parametric distribution, so the Kruskal-Wallis test was used to compare between the types of implants. The Mann-Whitney U te...

Methods : Peri-implant biomechanical responses to ...

Each crown was cemented to its corresponding implant-abutment assembly using temporary cement (Cavex Temporary Cement, Cavex, Holland). Each implant received 4 strain gauges (Kowa strain gages, Japan) placed on the mesial, distal, buccal, and lingual surfaces of the epoxy resin adjacent to the implants. At these selected sites, the thickness of the epoxy resin surrounding each implant was reduced...

Methods : Peri-implant biomechanical responses to ...

In the present study, the following materials were used: titanium root form endosseous implants of standard diameter and length (4-mm platform, 3.8-mm diameter,12-mm length, fixture bevel 0.2 mm, Super Line System, Dentium, USA), short-wide implant (7-mm platform, 5.8-mm diameter, 7-mm length, Super Line System, Dentium, Seoul, Korea) with 1.5-mm machined surface and 5.5-mm threaded surface that ...

Background : Peri-implant biomechanical responses ...

There are several factors that affect force magnitudes in peri-implant bone. The application of functional forces induces stresses and strains within the implant prosthesis complex and affect the bone remodeling process around implants [8, 9]. While there are several methods of measuring strain, the most common is with a strain gauge, a device whose electrical resistance varies in proportion to t...

Background : Peri-implant biomechanical responses ...

The molars are one of the first teeth to be lost over lifetime; thus, their replacement is frequently needed. Implantation is generally the preferred choice to replace a missing single tooth avoiding vital teeth preparation and bridge fabrication [1]. The mandibular bone loss occurs as knife-edge residual ridge where there is marked narrowing of the labiolingual diameter of the crest of the ridge...

Abstract : Peri-implant biomechanical responses to...

The aim of this study was to evaluate the biomechanical response of the peri-implant bone to standard, short-wide, and double mini implants replacing missing molar supporting either hybrid ceramic crowns (Lava Ultimate restorative) or full-metal crowns under two different loading conditions (axial and off-axial loading) using strain gauge analysis. Three single-molar implant designs, (1) single, ...

Fig. 1. Flow diagram : Implant decontamination wit...

Fig. 1. Flow diagram Fig. 1. Flow diagram

Table 5 Average differences in BoP, SoP, and PPD b...

Outcome variable Crude modela β (95% CI) p value Adjusted modelb β (95% CI) p-value % Sites BoP ...

Table 4 Descriptive statistics of clinical paramet...

  Control Test T0 (n = 22) T3 (n = 20) T0 (n = 31) T3 (n = 30) ...

Table 3 Log-transformed mean bacterial anaerobic c...

N = 47a Total anaerobic bacterial load Log-transformed mean (SD)   T0 T3 Difference β (95% CI)b p value Control ...

Table 2 Log-transformed mean bacterial anaerobic c...

N = 40a Total anaerobic bacterial load Log-transformed mean (SD)   Tpre Tpost Difference β (95% CI)b p value ...

Table 1 Characteristics of included patients/impla...

Characteristics Control Test Number of patients 14 14 ...

About this article : Implant decontamination with ...

Hentenaar, D.F.M., De Waal, Y.C.M., Strooker, H. et al. Implant decontamination with phosphoric acid during surgical peri-implantitis treatment: a RCT. Int J Implant Dent 3, 33 (2017). https://doi.org/10.1186/s40729-017-0091-5 Download citation Received: 28 March 2017 Accepted: 22 June 2017 Published: 17 July 2017 DOI: https://doi.org/10.1186/s40729-017-0091-5

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Implant decontamination with...

Diederik F. M. Hentenaar, Yvonne C. M. de Waal, Hans Strooker, Henny J. A. Meijer, Arie-Jan van Winkelhoff, and Gerry M. Raghoe declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Implant decontamination with ...

Correspondence to Gerry M. Raghoebar.

Author information : Implant decontamination with ...

Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands Diederik F. M. Hentenaar, Henny J. A. Meijer & Gerry M. Raghoebar Center for Dentistry and Oral Hygiene, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands Yvonne C. M. De Waal, Hans Strooker, He...

References : Implant decontamination with phosphor...

Van Winkelhoff AJ, van Steenbergen TJ, Kippuw N, De Graaff J. Further characterization of Bacteroides endodontalis, an asaccharolytic black-pigmented Bacteroides species from the oral cavity. J Clin Microbiol. 1985;22:75–9. Zambon JJ. Periodontal diseases: microbial factors. Ann Periodontol. 1996;1:879–925. Héritier M. Effects of phosphoric acid on root dentin surface. A scanning and transm...

References : Implant decontamination with phosphor...

Htet M, Madi M, Zakaria O, Miyahara T, Xin W, Lin Z, Aoki K, Kasugai S. Decontamination of anodized implant surface with different modalities for peri-implantitis treatment: lasers and mechanical debridement with citric acid. J Periodontol. 2016;87:953–61. Mouhyi J, Sennerby L, Van Reck J. The soft tissue response to contaminated and cleaned titanium surfaces using CO2 laser, citric acid and hy...

References : Implant decontamination with phosphor...

Esposito M, Grusovin MG, Worthington HV. Treatment of peri-implantitis: what interventions are effective? A Cochrane systematic review. Eur J Oral Implantol. 2012;5:21–41. Louropoulou A, Slot DE, Van der Weijden F. The effects of mechanical instruments on contaminated titanium dental implant surfaces: a systematic review. Clin Oral Implants Res. 2014;25:1149–60. Ramanauskaite A, Daugela P, F...

References : Implant decontamination with phosphor...

Lang NP, Berglundh T, Working Group 4 of Seventh European Workshop on Periodontology. Periimplant diseases: where are we now?—Consensus of the Seventh European Workshop on Periodontology. J Clin Periodontol. 2011;38(Suppl):11,178–181. Derks J, Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol. 2015;42:158–71. Derks J, Schaller D, Hå...

Abbreviations : Implant decontamination with phosp...

Gerry Raghoebar Diederik Hentenaar Yvonne de Waal

Conclusions : Implant decontamination with phospho...

Implant surface decontamination is considered a highly susceptible step in the treatment of peri-implantitis. The application of 35% phosphoric acid after mechanical debridement is superior to mechanical debridement combined with sterile saline rinsing for decontamination of the implant surface during surgical peri-implantitis treatment. However, phosphoric acid as implant surface decontaminant do...

Discussion : Implant decontamination with phosphor...

Recent studies that zoom in on titanium surface physico-chemistry reveal interesting results [38, 39]. Kotsakis et al. [38] hypothesized that chemical residues alter the titanium surface physicochemistry and subsequently compromise cellular response to these decontaminated surfaces. However, they report on effective restoring of biocompatibility when sterile saline, citric acid, and EDTA/sodium hy...

Discussion : Implant decontamination with phosphor...

Phosphoric acid gel as agent for implant surface decontamination has only been investigated in two other clinical studies [26, 27]. Strooker et al. [26] used phosphoric acid 35% for peri-implant supportive therapy and found greater reductions in bacterial load, but no significant clinical differences compared to conventional mechanical supportive therapy. They concluded that local application of 3...

Discussion : Implant decontamination with phosphor...

This randomized controlled trial aimed to determine the effect of 35% phosphoric etching gel on decontamination of the implant surface during resective surgical treatment of peri-implantitis. Both decontamination procedures (mechanical debridement with curettes and gauzes combined with phosphoric acid 35% and mechanical debridement combined with sterile saline) resulted in a significant immediate ...

Results : Implant decontamination with phosphoric ...

The progress of patients throughout the different phases of the study is illustrated in Fig. 1. Table 1 depicts the baseline demographic patient and implant characteristics. The included patients had a total of 128 implants of which 53 implants showed signs of peri-implantitis. Different implant brands and types with different implant surfaces were present, including Straumann (Straumann AG, Bas...

Methods : Implant decontamination with phosphoric ...

Angular bony defects were eliminated, and bone was recontoured using a rotating round bur under saline irrigation. Mucosal flaps were apically positioned and firmly sutured (Vicryl Plus® 3-0; Ethicon Inc., Somerville, NJ, USA), and suprastructures were re-positioned. For both control and test group, surgery was followed by 2 weeks of mouth rinsing with 0.12% CHX + 0.05% CPC without alcohol t...

Methods : Implant decontamination with phosphoric ...

Implant mobility; Implants at which no position could be identified where proper probing measurements could be performed; Previous surgical treatment of the peri-implantitis lesions. The study protocol was based on the study protocols of two previous studies evaluating the decontaminating effect of chlorhexidine during surgical peri-implantitis treatment [10, 32] and is briefly described below....

Methods : Implant decontamination with phosphoric ...

The present study is a double-blind randomized controlled trial evaluating the effect of 35% phosphoric etching gel (test group) compared to the effect of saline (control group) for implant surface decontamination combined with mechanical debridement during surgical peri-implantitis treatment. Patients were randomly assigned to the test or control group using a one-to-one allocation ratio. The stu...

Background : Implant decontamination with phosphor...

Thus far, the use of phosphoric acid etching gel as decontaminating agent has not been evaluated in a randomized controlled trial. The aim of the present randomized controlled trial is to evaluate the short-term microbiological and clinical effectiveness of 35% phosphoric etching gel as a decontaminating agent of the implant surface during resective surgical treatment of peri-implantitis.

Background : Implant decontamination with phosphor...

Triggered host defense responses initiate inflammation of the peri-implant soft tissue (peri-implant mucositis), which can lead to loss of peri-implant supporting bone (peri-implantitis), and eventually, result in implant failure [1]. An increasing prevalence of peri-implantitis has been described in recent literature [2], with current incidence ranging from 1 to 47%. A non-linear, accelerating pa...

Abstract : Implant decontamination with phosphoric...

Peri-implantitis is known as an infectious disease that affects the peri-implant soft and hard tissue. Today, scientific literature provides very little evidence for an effective intervention protocol for treatment of peri-implantitis. The aim of the present randomized controlled trial is to evaluate the microbiological and clinical effectiveness of phosphoric acid as a decontaminating agent of th...

Fig. 7. Vestibular view of the final restoration :...

Fig. 7. Vestibular view of the final restoration Fig. 7. Vestibular view of the final restoration

Fig. 6. Occlusal view of the final restoration. In...

Fig. 6. Occlusal view of the final restoration. In this case, with the longest cantilever extension on a final restoration within this collective Fig. 6. Occlusal view of the final restoration. In this case, with the longest cantilever extension on a final restoration within this collective

Fig. 5. One-year post-surgery panoramic radiograph...

Fig. 5. One-year post-surgery panoramic radiograph with final restoration Fig. 5. One-year post-surgery panoramic radiograph with final restoration

Fig. 4. Occlusal view of implant-abutments 3 mont...

Fig. 4. Occlusal view of implant-abutments 3 months post-surgery at the first removal of the temporary restoration Fig. 4. Occlusal view of implant-abutments 3 months post-surgery at the first removal of the temporary restoration

Fig. 3. Fill-in of the occlusal perforations with ...

Fig. 3. Fill-in of the occlusal perforations with self-curing resin to connect the prostheses to the temporary titanium cylinders Fig. 3. Fill-in of the occlusal perforations with self-curing resin to connect the prostheses to the temporary titanium cylinders

Fig. 2. Preparation of the composite veneers for m...

Fig. 2. Preparation of the composite veneers for making the temporary restoration Fig. 2. Preparation of the composite veneers for making the temporary restoration

Fig. 1. Preparation of implant cavity through corr...

Fig. 1. Preparation of implant cavity through corresponding metal sleeves after extraction of the central incisors using a surgical template supported by hopeless remaining teeth Fig. 1. Preparation of implant cavity through corresponding metal sleeves after extraction of the central incisors using a surgical template supported by hopeless remaining teeth

Table 5 Marginal bone loss measured in mm : Six-im...

Collective Mesial Distal 1 year 55 months (40–84) 1 year ...

Table 4 Mean implant stability quotients (ISQ) of ...

Collective ISQ P At insertion 3 months Total (n = 57) 61.3 ± 7.8 ...

Table 3 Mean Periotest values (PT) of survived axi...

Collective PT value P At insertion 3 months Total (n = 57) −1.8 ± 2.4 ...

Table 2 Life table of implants : Six-implant-suppo...

Period # of implants # of failures Survival rate (%) Cumulative survival rate (%) 0 t...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Six-implant-supported immedi...

The retrospective data analysis was conducted in accordance with the Helsinki Declaration of 1975, as revised in 2008, and all patients signed an informed consent. After consulting the local ethic committee, the decision was that due to the retrospective character of this study, with no additional data acquisition, no ethical approval is needed according to the hospital laws of the appropriate sta...

Author information : Six-implant-supported immedia...

Department of Prosthetic Dentistry, University Medical Center of the Johannes Gutenberg-University Mainz, Augustusplatz 2, 55131, Mainz, Germany S. Wentaschek & S. Hartmann Department of Oral and Maxillofacial Surgery - Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Augustusplatz 2, 55131, Mainz, Germany C. Walter & W. Wagner You can also search for ...

Acknowledgements : Six-implant-supported immediate...

The authors would like to thank Bredent Medical (Senden, Germany) for providing the 3D-planning system and supporting the treatment nonfinancially.

References : Six-implant-supported immediate fixed...

Download references

References : Six-implant-supported immediate fixed...

Bayer G, Kistler F, Kistler S, Adler S, Neugebauer J. Sofortversorgung mit reduzierter Implantatanzahl: Wissenschaftliche Konzeption und klinische Ergebnisse. Berlin: Quintessenz; 2011. Hanley JA. Receiver operating characteristic (ROC) methodology: the state of the art. Crit Rev Diagn Imaging. 1989;29(3):307–35. Atieh MA, Alsabeeha NH, Payne AG, de Silva RK, Schwass DS, Duncan WJ. The prognos...

References : Six-implant-supported immediate fixed...

Pommer B, Mailath-Pokorny G, Haas R, Busenlechner D, Furhauser R, Watzek G. Patients’ preferences towards minimally invasive treatment alternatives for implant rehabilitation of edentulous jaws. Eur J Oral Implantol. 2014;7(Suppl 2):S91–109. Monje A, Suarez F, Galindo-Moreno P, Garcia-Nogales A, Fu JH, Wang HL. A systematic review on marginal bone loss around short dental implants (

Abbreviations : Six-implant-supported immediate fi...

Area under the curve Implant stability quotient Periotest Receiver operating characteristic

Conclusions : Six-implant-supported immediate fixe...

Within the limits of this small group (n = 10 patients/60 implants), the failure rate of the analyzed implant system (n = 3 respective 5% implant loss) seems to be comparable with other immediate-loading protocols. On the other side, the implant loss rate of tilted implants (n = 2 of 20) in the atrophic upper jaw was quite high, but still, the aimed treatment concept could be achieved in eve...

Discussion : Six-implant-supported immediate fixed...

Between baseline and first removal of the temporary restoration after 3 months, the mean ISQ increased and the mean PT value decreased significantly in the axial and tilted implants. This is in contrast to some other studies which evaluated no significant differences of stability parameters between primary and secondary stability with immediate loading in edentulous maxilla [16, 21, 22]. The pre...

Discussion : Six-implant-supported immediate fixed...

The overall implant survival rate of 95% is slightly lower than the reported mean survival rates of the concept of tilted implants and immediate loading in edentulous jaws [11] but still close to them and maybe more comparable to investigations in which implants were also immediately loaded in the edentulous maxilla which were partly placed in fresh extraction sites [15, 16]. Nevertheless, what is...

Results : Six-implant-supported immediate fixed re...

After the temporary restoration with a fixed prosthesis, all 10 patients selected a fixed final restoration. These consisted of a cast metal framework with a full ceramic veneering including the replacement of at least the second premolars. They were made after a new impression on the abutment level (Figs. 6 and 7). The neck of the 20 tilted distal implants was positioned in region 4 (n = 5 impl...

Results : Six-implant-supported immediate fixed re...

Ten patients with a mean age at implant insertion of 64 ± 11.3 years (range 38 to 81 years; six women, four men) were included. Sixty titanium screw implants (Table 1) were inserted and immediately loaded between 09/2009 and 01/2013. Seven patients had remaining teeth until implant surgery (two patients with 4, four patients with 7, and one patient with 12 teeth). Twenty-one (35%) of the 60 ...

Methods : Six-implant-supported immediate fixed re...

Changes in marginal bone level were measured using the routinely made digital panoramic radiographs if these were available. The measurement tool was calibrated with the known respective implant length. To evaluate the bone loss, the difference was formed between the bone level at follow-up examination (Fig. 5) and at implant placement which is the baseline. An implant was considered as successfu...

Methods : Six-implant-supported immediate fixed re...

The patients were screened with preliminary panoramic radiographs, and since all the implants were 3D planned (SKYplanX™ program, Bredent GmbH, Senden, Germany) and inserted with a guiding template, a cone-beam CT (CBCT) was obtained eventually (KaVo 3D eXam™ unit, KaVo Dental GmbH, Biberach/Riss, Germany). The drillings were performed using a 3D-planned surgical template with different metal...

Methods : Six-implant-supported immediate fixed re...

In a retrospective study, all patients with immediately loaded implants in an edentulous maxillae with limited posterior ridge dimensions that received an equal concept were included if they had a follow-up of at least 3 years. The concept contained immediate loading with distal tilted implants and six implants per edentulous maxillae of a single implant system (blueSky™ implants, Bredent GmbH,...

Background : Six-implant-supported immediate fixed...

For a few years, there has been a trend towards minimally invasive implant treatment concepts avoiding bone augmentation even in very atrophic edentulous jaws. These concepts aim to make an implant treatment with a shorter duration, with less inconvenience such as swelling or pain and possibly also economically more attractive [1]. If the implant treatment is less invasive, because of the possible...

Abstract : Six-implant-supported immediate fixed r...

The aim of this retrospective study was to evaluate the treatment outcome of six Bredent blueSky™ implants (Bredent GmbH, Senden, Germany) immediately loaded with a fixed full-arch prosthesis (two tilted posterior and four axial frontal and premolar implants). All 10 patients with atrophic edentulous maxillae being treated with a standardized procedure from 09/2009 to 01/2013, who had a follow-...

Fig. 17. The appearance of the case shown in Fig. ...

Fig. 17. The appearance of the case shown in Fig. 16 with the polythene “washer” removed at 2 weeks post-surgery, providing access to the zygomatic oncology implants Fig. 17. The appearance of the case shown in Fig. 16 with the polythene “washer” removed at 2 weeks post-surgery, providing access to the zygomatic oncology implants

Fig. 16. Another ZIP flap case demonstrating the u...

Fig. 16. Another ZIP flap case demonstrating the use of a perforated polythene “washer” to keep the flap from overgrowing the implant abutments during the healing phase Fig. 16. Another ZIP flap case demonstrating the use of a perforated polythene “washer” to keep the flap from overgrowing the implant abutments during the healing phase

Fig. 15. Facial appearance 18 months following tr...

Fig. 15. Facial appearance 18 months following treatment Fig. 15. Facial appearance 18 months following treatment

Fig. 14. Intra-oral view of perforated flap 3 wee...

Fig. 14. Intra-oral view of perforated flap 3 weeks following radiotherapy Fig. 14. Intra-oral view of perforated flap 3 weeks following radiotherapy

Fig. 13. Panoramic dental radiograph showing the p...

Fig. 13. Panoramic dental radiograph showing the position of the zygomatic implants and the seating of the initial fixed prosthesis Fig. 13. Panoramic dental radiograph showing the position of the zygomatic implants and the seating of the initial fixed prosthesis

Fig. 12. Provisional acrylic fixed dental prosthes...

Fig. 12. Provisional acrylic fixed dental prosthesis fitted at 4 weeks post-surgery Fig. 12. Provisional acrylic fixed dental prosthesis fitted at 4 weeks post-surgery

Fig. 11. Intra-oral view of the soft tissue flap a...

Fig. 11. Intra-oral view of the soft tissue flap at 3 weeks post-operatively with overgrowth of flap over the zygomatic oncology implants Fig. 11. Intra-oral view of the soft tissue flap at 3 weeks post-operatively with overgrowth of flap over the zygomatic oncology implants

Fig. 10. Radial forearm flap inset and sutured int...

Fig. 10. Radial forearm flap inset and sutured into the maxillary defect and perforated by the zygomatic oncology implant abutments Fig. 10. Radial forearm flap inset and sutured into the maxillary defect and perforated by the zygomatic oncology implant abutments

Fig. 9. Inter-occlusal registration using the pre-...

Fig. 9. Inter-occlusal registration using the pre-fabricated maxillary denture prosthesis relined with silicone putty over the implant abutment protection caps Fig. 9. Inter-occlusal registration using the pre-fabricated maxillary denture prosthesis relined with silicone putty over the implant abutment protection caps

Fig. 8. Abutment level impression utilising light-...

Fig. 8. Abutment level impression utilising light-cured acrylic tray material Fig. 8. Abutment level impression utilising light-cured acrylic tray material

Fig. 7. Conventional zygomatic implant insertion o...

Fig. 7. Conventional zygomatic implant insertion on the non-defect side of the maxilla following extraction of the remaining teeth and an alveoloplasty Fig. 7. Conventional zygomatic implant insertion on the non-defect side of the maxilla following extraction of the remaining teeth and an alveoloplasty

Fig. 6. Zygomatic oncology implants sited in the r...

Fig. 6. Zygomatic oncology implants sited in the residual zygomatic bone on the defect side of the maxilla Fig. 6. Zygomatic oncology implants sited in the residual zygomatic bone on the defect side of the maxilla

Fig. 5. Left-sided maxillary resection (Brown clas...

Fig. 5. Left-sided maxillary resection (Brown class 2b) Fig. 5. Left-sided maxillary resection (Brown class 2b)

Fig. 4. Panoramic dental radiograph showing dental...

Fig. 4. Panoramic dental radiograph showing dental status at presentation Fig. 4. Panoramic dental radiograph showing dental status at presentation

Fig. 3. Staging CT scan confirming maxillary destr...

Fig. 3. Staging CT scan confirming maxillary destruction but preservation of the orbital floor Fig. 3. Staging CT scan confirming maxillary destruction but preservation of the orbital floor

Fig. 2. Staging MRI scan showing destructive lesio...

Fig. 2. Staging MRI scan showing destructive lesion left maxilla Fig. 2. Staging MRI scan showing destructive lesion left maxilla

Fig. 1. Clinical view of left-sided maxillary tumo...

Fig. 1. Clinical view of left-sided maxillary tumour at presentation Fig. 1. Clinical view of left-sided maxillary tumour at presentation

Table 1 Patient-reported quality of life outcomes ...

Domain Score Activity 100 (“I am as active as I have ever been”) Anxiety 100 (“...

About this article : The zygomatic implant perfora...

Butterworth, C.J., Rogers, S.N. The zygomatic implant perforated (ZIP) flap: a new technique for combined surgical reconstruction and rapid fixed dental rehabilitation following low-level maxillectomy. Int J Implant Dent 3, 37 (2017). https://doi.org/10.1186/s40729-017-0100-8 Download citation Received: 14 May 2017 Accepted: 23 July 2017 Published: 29 July 2017 DOI: https...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : The zygomatic implant perfor...

Consent has been obtained from the patient for the use and publication of all images. Chris Butterworth and Simon Rogers declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : The zygomatic implant perfora...

Department of Oral & Maxillofacial Surgery, University Hospital Aintree, Lower Lane, Liverpool, L9 7AL, UK C. J. Butterworth & S. N. Rogers You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar CB devised the treatment concept and undertook all implant surgeries and prostho...

References : The zygomatic implant perforated (ZIP...

Okay DJ, Genden E, Buchbinder D, Urken M. Prosthodontic guidelines for surgical reconstruction of the maxilla: a classification system of defects. J Prosthet Dent. 2001;86(4):352–63. Rohner D, Bucher P, Hammer B. Prefabricated fibular flaps for reconstruction of defects of the maxillofacial skeleton: planning, technique, and long-term experience. Int J Oral Maxillofac Implants. 2013;28(5):e221...

Conclusions : The zygomatic implant perforated (ZI...

The ZIP flap technique represents an innovative approach to the management of patients presenting with low-level malignant maxillary tumours. It provides effective closure of the resulting maxillary defect restoring speech and swallowing functions and also establishing a high-quality fixed dental rehabilitation in a rapid timescale, thus facilitating a more timely return to function and restored f...

Case presentation : The zygomatic implant perforat...

Whilst technically, it would be possible to construct and fit the prosthesis on the same day or even a week later, the need for microvascular flap monitoring in the immediate post-operative period, together with the significant recovery period required by the patient following surgery has lead the authors to delay the fitting of the prosthesis at the 4 to 6-week period post-operatively. In terms o...

Case presentation : The zygomatic implant perforat...

In contrast, the use of a soft tissue flap such as the RFFF or antero-lateral thigh flap can often be safely employed in elderly patients with peripheral vascular disease without unduly lengthening the operation too significantly with two-team operating. In addition, the predictability of these flaps with their excellent pedicle lengths is ideal for closure of the resulting oro-nasal surgical defe...

Case presentation : The zygomatic implant perforat...

In low-level maxillectomy (Brown class II), the need for bony reconstruction is questionable depending on the horizontal component. With the preservation of the orbital floor, zygomatic prominence and some bony support for the nose, facial appearance, in the experience of the authors and, as demonstrated by this case, is not significantly worsened despite low-level removal of the maxilla. The key ...

Case presentation : The zygomatic implant perforat...

In order to address some of the issues highlighted in this early case, the technique was modified slightly to try and prevent flap overgrowth and prosthesis fracture in the early stages. In order to prevent flap overgrowth over the zygomatic oncology implant abutments, the use of a polythene washer was instituted on subsequent cases treated in the unit. Once the flap was perforated, a 2-mm thick p...

Case presentation : The zygomatic implant perforat...

The implant positions were then accurately registered by utilising light-cured resin tray material (Individo® Lux, Voco Gmbh, Germany) and abutment level impression copings. The resin material was applied in sections around the impression copings and cured incrementally to ensure a rigid splinting of the impression copings (Fig. 8). Abutment protection caps were then placed over all four abutment...

Case presentation : The zygomatic implant perforat...

A 66-year-old male patient presented with an enlarging mass in the left maxilla (Fig. 1). The mass had been present for a few weeks. An incisional biopsy revealed squamous cell carcinoma. Staging scans were undertaken (Fig. 2) which demonstrated a T4N0M0 maxillary alveolus tumour in close proximity to the left orbital floor with obliteration of the maxillary antrum and destruction of the lateral m...

Background : The zygomatic implant perforated (ZIP...

The surgical management and prosthodontic rehabilitation of the maxillectomy patient is complex with a variety of options available to the head and neck cancer team ranging from simple prosthodontic obturation [1] to reconstruction using pre-fabricated or digitally planned composite flaps [2] with or without the placement of osseointegrated implants [3]. The primary aims of treatment include effec...

Abstract : The zygomatic implant perforated (ZIP) ...

This aim of this report is to describe the development and evolution of a new surgical technique for the immediate surgical reconstruction and rapid post-operative prosthodontic rehabilitation with a fixed dental prosthesis following low-level maxillectomy for malignant disease. The technique involves the use of a zygomatic oncology implant perforated micro-vascular soft tissue flap (ZIP flap) fo...

Fig. 5. Change in BoP values according to the perc...

Fig. 5. Change in BoP values according to the percentage of sites with a score of 1, 2 or 3 by visit Fig. 5. Change in BoP values according to the percentage of sites with a score of 1, 2 or 3 by visit

Fig. 4. Percentages of sites with PPD 1–3, 4–5...

Fig. 4. Percentages of sites with PPD 1–3, 4–5 and ≥6 mm by visit (p 

Fig. 3. Changes in BoP values between baseline and...

Fig. 3. Changes in BoP values between baseline and the various examination time points Fig. 3. Changes in BoP values between baseline and the various examination time points

Fig. 2. Changes in PPD values between baseline and...

Fig. 2. Changes in PPD values between baseline and the various examination time points Fig. 2. Changes in PPD values between baseline and the various examination time points

Fig. 1. A chitosan brush (LBC, BioClean®, LABRIDA...

Fig. 1. A chitosan brush (LBC, BioClean®, LABRIDA AS) seated in an oscillating dental handpiece Fig. 1. A chitosan brush (LBC, BioClean®, LABRIDA AS) seated in an oscillating dental handpiece

Table 3 Level of crown margin at the different tim...

  Baseline n = 306 2 weeks n = 272 4 weeks n = 267 12 weeks n = 282 24 weeks n = 294 P ...

Table 2 Demographics by center : A novel non-surgi...

Center Oslo Jonkoping Rome Stavanger Kristianstad Tons...

About this article : A novel non-surgical method f...

Wohlfahrt, J.C., Evensen, B.J., Zeza, B. et al. A novel non-surgical method for mild peri-implantitis- a multicenter consecutive case series. Int J Implant Dent 3, 38 (2017). https://doi.org/10.1186/s40729-017-0098-y Download citation Received: 08 April 2017 Accepted: 13 July 2017 Published: 03 August 2017 DOI: https://doi.org/10.1186/s40729-017-0098-y

Rights and permissions : A novel non-surgical meth...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : A novel non-surgical method ...

J.C. Wohlfahrt is the inventor and patent holder of BioClean and is a shareholder in LABRIDA AS. B.J. Evensen, B. Zeza, H. Jansson, A. Pilloni, A.M. Roos-Jansåker, G.L. Di Tanna, A.M. Aass, M. Klepp and O.C. Koldsland state that there were no conflicts of interests during the undertaking of the study. Ethical approval was provided by the regional ethical review boards of each center (Norway: 201...

Author information : A novel non-surgical method f...

You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar JCW, BJE, BZ, HJ, AP, AMR-J, AMA, MK and OCK par...

Author information : A novel non-surgical method f...

Department of Periodontology, Institute of Clinical Dentistry, University of Oslo, Pb. 1109 Blindern, 0317, Oslo, Norway J. C. Wohlfahrt, A. M. Aass & O. C. Koldsland Private Practice, Tønsberg, Norway B. J. Evensen Department of Dental and Maxillofacial Sciences, Section of Periodontology, Sapienza, University of Rome, Rome, Italy B. Zeza & A. Pilloni Center for Oral Health, Departmen...

References : A novel non-surgical method for mild ...

Salvi GE, et al. Reversibility of experimental peri-implant mucositis compared with experimental gingivitis in humans. Clin Oral Implants Res. 2012;23(2):182–90. Korsch M, Obst U, Walther W. Cement-associated peri-implantitis: a retrospective clinical observational study of fixed implant-supported restorations using a methacrylate cement. Clin Oral Implants Res. 2014;25(7):797–802. Download ...

References : A novel non-surgical method for mild ...

Muthukuru M, et al. Non-surgical therapy for the management of peri-implantitis: a systematic review. Clin Oral Implants Res. 2012;23(Suppl 6):77–83. Esposito M, Grusovin MG, Worthington HV. Treatment of peri-implantitis: what interventions are effective? A Cochrane systematic review. Eur J Oral Implantol. 2012;5(Suppl):S21–41. Armitage GC, Xenoudi P. Post-treatment supportive care for the n...

References : A novel non-surgical method for mild ...

Rokn A, et al. Prevalence of peri-implantitis in patients not participating in well-designed supportive periodontal treatments: a cross-sectional study. Clin Oral Implants Res. 2017;28(3):314–9. Faggion CM Jr, et al. A systematic review and Bayesian network meta-analysis of randomized clinical trials on non-surgical treatments for peri-implantitis. J Clin Periodontol. 2014;41(10):1015–25. Me...

References : A novel non-surgical method for mild ...

Koldsland OC, Scheie AA, Aass AM. Prevalence of peri-implantitis related to severity of the disease with different degrees of bone loss. J Periodontol. 2010;81(2):231–8. Roos-Jansaker AM, et al. Nine- to fourteen-year follow-up of implant treatment. Part II: presence of peri-implant lesions. J Clin Periodontol. 2006;33(4):290–5. Derks J, et al. Effectiveness of implant therapy analyzed in a ...

Conclusions : A novel non-surgical method for mild...

In this multicenter case series of implants affected by mild peri-implantitis, significant reductions in the clinical parameters of inflammation were demonstrated at all time points after the initial treatment with a chitosan brush. The use of an oscillating chitosan device appears to be safe and has potential merits for the treatment of mild peri-implantitis and for the maintenance of dental impl...

Discussion : A novel non-surgical method for mild ...

The chitosan brush used in this study is made of a material that is soft with the aim to make a device optimized for removal of the biofilm within the implant threads. The soft bristles on the contrary make the device suboptimal for removal of hard deposits, such as calculus and cement remnants. It has been reported that such cement remnants are a common finding around dental implants [41], and in...

Discussion : A novel non-surgical method for mild ...

In the present study, significant reductions were observed in the clinical parameters of peri-implant inflammation at 2, 4, 12 and 24 weeks relative to baseline after debridement with the chitosan brush seated in an oscillating dental drill piece. No progression in radiographic bone loss was reported at any of the implants at the final evaluation, and the method was thus judged safe to use in cas...

Discussion : A novel non-surgical method for mild ...

Identifying peri-implant disease at an early stage and promptly treating the inflammatory condition is crucial to prevent the progression of peri-implant bone loss and ensure long-term implant survival [23,24,25]. After completion of active treatment and when the condition is controlled, supportive peri-implant therapy will reduce the risk of disease re-occurrence [9]. A number of scientific repor...

Results : A novel non-surgical method for mild per...

During this study, all 63 implants were reported to have stable radiographic levels of osseous support as validated by the six different local examiners. No adverse events were reported during the study.

Results : A novel non-surgical method for mild per...

In total, 63 implants in 63 patients were ultimately included in the analysis. Demographic information is presented in Tables 1 and 2. Significant reductions in both PPD and mBoP were seen at all time points relative to the baseline clinical measurements (p 

Case presentation : A novel non-surgical method fo...

Mann-Whitney rank sum tests were used to compare changes in the clinical parameters between baseline and subsequent time points. To assess the hierarchical structure of the data (center > patient > site), a linear mixed model using the restricted maximum likelihood method (multilevel logistic models for binary outcomes) was constructed to analyse the PPD, mBoP and suppuration, adjusting for fac...

Case presentation : A novel non-surgical method fo...

All patient-related information and clinical recordings were recorded in a web-based clinical research form (VieDoc version 3.24, PCG solutions, Uppsala, Sweden). Patients under 18 years of age; current smokers; patients who had undergone radiotherapy in the head and neck region, chemotherapy or systemic long-term corticosteroid treatment; patients who were pregnant or nursing; patients receivin...

Case presentation : A novel non-surgical method fo...

A 6-month multicenter prospective consecutive case series was performed in six different periodontal specialist clinics in Norway, Sweden and Italy. Ethical approval was provided by the regional ethical review boards of each center (Norway: 2014/852/REK sør-øst; Italy: Sapienza 2011/15, 3547; and Sweden: EPN Lund 2014/695.) Fifteen patients at each center were planned to be included in the stud...

Background : A novel non-surgical method for mild ...

A number of other studies also report that leaving fragments of the instrument on the implant surface or scratching the surface may impede optimal peri-implant healing [17,18,19,20]. Chitosan is a marine biopolymer which is based on chitin derived from the shells of marine crustaceans. The material has been approved for use in surgical bandages, as a haemostatic agent and as a dietary supplement ...

Background : A novel non-surgical method for mild ...

Inflammation and loss of attachment around dental implants (i.e. peri-implantitis) has become a growing concern within the field of dental implantology [1,2,3,4,5,6,7]. Peri-implantitis is a microbial infection-driven soft tissue inflammation with loss of bony attachment around an implant. Peri-implant mucositis is the precursor of peri-implantitis, as gingivitis is for periodontitis [8]. It is cl...

Abstract : A novel non-surgical method for mild pe...

The aim of the present study was to evaluate the effect on peri-implant mucosal inflammation from the use of a novel instrument made of chitosan in the non-surgical treatment of mild peri-implantitis across several clinical centers. In this 6-month multicenter prospective consecutive case series performed in six different periodontal specialist clinics, 63 implants in 63 patients were finally inc...

Fig. 2. Clinical image of patient 4: a region 21 b...

Fig. 2. Clinical image of patient 4: a region 21 before implant placement. b, c Implant placement using the GBR procedure with a synthetic bone substitute material composed of HA + β-TCP Fig. 2. Clinical image of patient 4: a region 21 before implant placement. b, c Implant placement using the GBR procedure with a synthetic bone substitute material composed of HA + β-TCP

Fig. 1. Schematic representation of the technical ...

Fig. 1. Schematic representation of the technical characteristics of the investigated C-Tech Esthetic Line implant system (provided by the manufacturer) Fig. 1. Schematic representation of the technical characteristics of the investigated C-Tech Esthetic Line implant system (provided by the manufacturer)

Table 2 Results from the clinical and radiological...

Patient Implant-localization (region) Implant loss (+/−) Buccal width of keratinized peri-implant gingiva (mm) Buccal thickness of keratinized peri-implant gi...

Table 1 Participating patients and the number and ...

Patient Gender (m/f) Age (years) Implant localization (region) Implant diameter (mm) ...

About this article : Investigation of peri-implant...

Lorenz, J., Lerner, H., Sader, R.A. et al. Investigation of peri-implant tissue conditions and peri-implant tissue stability in implants placed with simultaneous augmentation procedure: a 3-year retrospective follow-up analysis of a newly developed bone level implant system. Int J Implant Dent 3, 41 (2017). https://doi.org/10.1186/s40729-017-0104-4 Download citation Received...

Rights and permissions : Investigation of peri-imp...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Investigation of peri-implan...

This study was conducted in compliance with the principles of the Declaration of Helsinki, and the approval of the ethics committee required for the study was obtained from the Ethics Committee of the Medical Center of the Goethe University Frankfurt. The procedures to be performed were explained in detail, and the patients signed the consent form. Jonas Lorenz, Henriette Lerner, Robert Sader, an...

Author information : Investigation of peri-implant...

Department for Oral, FORM-Lab, Cranio-Maxillofacial, and Facial Plastic Surgery, Medical Center of the Goethe University Frankfurt, Frankfurt am Main, Germany Jonas Lorenz, Robert A. Sader & Shahram Ghanaati HL-Dentclinic, Baden-Baden, Germany Henriette Lerner You can also search for this author in PubMed Google Scholar You can also search for this author in ...

References : Investigation of peri-implant tissue ...

Lerner H, Lorenz J, Sader R, Ghanaati S. Two-year retrospective study of periimplant health and periimplant bone stability after immediate implant placement of a newly developed bone level implant system—a first report. EDI Journal (European Association of Dental Implantologists, Teamwork Media); 2017; ahead of print. Ghanaati S, Lorenz J, Obreja K, Choukroun J, Landes C, Sader R. Nanocrystalli...

References : Investigation of peri-implant tissue ...

Gurgel BC, Montenegro SC, Dantas PM, Pascoal AL, Lima KC, Calderon PD. Frequency of peri-implant diseases and associated factors. Clin Oral Implants Res. 2016; doi: 10.1111/clr.12944 Qian J, Wennerberg A, Albrektsson T. Reasons for marginal bone loss around oral implants. Clin Implant Dent Relat Res. 2012;14(6):792–807. Berglundh T, Lindhe J, Ericsson I, Marinello C, Liljenberg B, Thomsen P....

Abbreviations : Investigation of peri-implant tiss...

β-tricalcium phosphate Bleeding on probing Fixed prosthetics Guided bone regeneration Hydroxyapatite Multinucleated giant cells Pink Esthetic Score Removable prosthetics

Conclusions : Investigation of peri-implant tissue...

In the present study, the implant and peri-implant hard- and soft-tissue stability was analyzed in a bone level implant system placed simultaneously with a GBR procedure 3 years after prosthetic loading. Peri-implant hard- and soft-tissue parameters such as width and thickness of peri-implant keratinized gingiva, probing depth, BOP, PES, peri-implant bone loss, and the presence of peri-implant os...

Discussion : Investigation of peri-implant tissue ...

Comparing the present results to the aforementioned study with the same implant system on immediately placed implants, it seems that the GBR augmentation procedure has no influence on the long-term stability of the implants. In both studies with different placement modalities and protocols, comparable clinical and radiological results were achieved. This leads to the assumption that the investigat...

Discussion : Investigation of peri-implant tissue ...

The tissue reaction, however, did not only differ in bone substitute materials of different origin but also in bone substitute materials of the same origin. In an in vivo trial, two xenogeneic bone substitute materials processed with different techniques were implanted subcutaneously in CD-1 mice for up to 60 days. Both bone substitute materials showed good integration within the peri-implant tis...

Discussion : Investigation of peri-implant tissue ...

In the present retrospective study, C-Tech bone level implants placed simultaneously with a GBR procedure around the implant shoulder were investigated clinically and radiologically after at least 3 years of loading to assess peri-implant tissue conditions and document peri-implant tissue stability. A total of 47 implants were placed in the upper (23 implants) and lower jaw (24 implants) of 20 p...

Results : Investigation of peri-implant tissue con...

Investigation of the esthetic appearance via PES revealed a mean point score of 10.1 (ranging from 7 to 13) from a maximum of 14. The highest values and therefore acceptance were found in the alveolar process deficiency and the soft-tissue level, which can be interpreted as a benefit of the augmentation procedure around the implant shoulder. Peri-implant bone loss calculated using the average bon...

Results : Investigation of peri-implant tissue con...

Altogether, 47 implants were placed in the upper and lower jaws of a total of 20 patients. In all implants, lateral augmentation in a GBR process was performed simultaneously with implant placement due to reduced horizontal or vertical height of the alveolar crest. A total of 23 implants were placed in the upper jaw and 24 implants in the lower jaw. The implant diameter varied between 3.5 mm (32 ...

Methods : Investigation of peri-implant tissue con...

Investigation parameters: Implant being in situ Width and thickness of peri-implant keratinized gingiva Pink Esthetic Score (PES) Probing depth BOP Peri-implant bone loss Presence of peri-implant osteolysis

Methods : Investigation of peri-implant tissue con...

In the present retrospective study, bone level implants (C-Tech Esthetic Line implants) were investigated clinically and radiologically. The bone level implant system has a Morse-locking conical implant-abutment connection with platform switching and an indexing hex that allows subcrestal implant placement and aims to prevent peri-implant bone loss. The surface of the implant system is manufacture...

Methods : Investigation of peri-implant tissue con...

In the present retrospective study, 47 dental implants (C-Tech Esthetic Line implants) from 20 patients (11 female, 9 male) with a mean age of 58.5 years (45–75 years) were analyzed clinically and radiologically. Implant placement and follow-up investigation was performed at the HL Dentclinic in Baden-Baden, Germany. The study was approved by the ethics commission of the medical department of ...

Background : Investigation of peri-implant tissue ...

The aim of the present retrospective investigation was to assess clinically and radiologically peri-implant tissue conditions and document peri-implant tissue stability in C-Tech implants when placed simultaneously with a GBR augmentation procedure after at least 3 years of loading.

Background : Investigation of peri-implant tissue ...

The ability of bone substitute materials to form a sufficient and stable implantation bed has been proven in numerous clinical trials; however, it is still to a certain degree unclear if the different tissue reactions have an impact on the establishment of a peri-implant infection, especially when these biomaterials are used for augmentations around the implant shoulder. Due to the two-stage desig...

Background : Investigation of peri-implant tissue ...

The prevalence of peri-implantitis has grown in the past few years and has become a major issue in implant dentistry. Long-term stable and healthy soft- and hard-tissue conditions should be achieved in combination with esthetically and functionally satisfying results. However, the rising number of placed implants in the past decades has come with an increase in the prevalence of peri-implantitis [...

Abstract : Investigation of peri-implant tissue co...

Guided bone regeneration (GBR) has been proven to be a reliable therapy to regenerate missing bone in cases of atrophy of the alveolar crest. The aim of the present retrospective analysis was to assess peri-implant tissue conditions and document peri-implant tissue stability in C-Tech implants when placed simultaneously with a GBR augmentation procedure. A total of 47 implants, which were placed ...

Fig. 6. Cumulative survival rate of complication-f...

Fig. 6. Cumulative survival rate of complication-free prostheses by a gender (p = 0.1220) and b type of prostheses (p 

Fig. 5. Kaplan-Meier cumulative survival rate of c...

Fig. 5. Kaplan-Meier cumulative survival rate of complication-free prostheses at 10, 15, and 25 years after the prosthesis setting Fig. 5. Kaplan-Meier cumulative survival rate of complication-free prostheses at 10, 15, and 25 years after the prosthesis setting

Fig. 4. Cumulative incidence of peri-implantitis b...

Fig. 4. Cumulative incidence of peri-implantitis by a gender (p = 0.0221), b implant type (p = 0.0128), c implant position (p = 0.2470), d presence of additional soft tissue management (p = 0.2488), and e width of keratinized mucosa around implant (p = 0.0045). Log rank test was used for assessing statistical significance Fig. 4. Cumulative incidence of peri-implantitis by a gender ...

Fig. 3. Cumulative incidence of peri-implantitis :...

Fig. 3. Cumulative incidence of peri-implantitis Fig. 3. Cumulative incidence of peri-implantitis

Fig. 2. Kaplan-Meier cumulative survival rates by ...

Fig. 2. Kaplan-Meier cumulative survival rates by a gender (p = 0.1049), b implant type (p = 0.6259), c implant position (p 

Fig. 1. Kaplan-Meier cumulative survival rate at 1...

Fig. 1. Kaplan-Meier cumulative survival rate at 10, 15, and 25 years after the prosthesis setting Fig. 1. Kaplan-Meier cumulative survival rate at 10, 15, and 25 years after the prosthesis setting

Table 7 Cox regression analyses for cumulative sur...

  Hazard ratio 95% confidence interval p value Gender (male) 1.82 0.946~3.487 ...

Table 6 Cox regression analyses for cumulative inc...

  Hazard ratio 95% confidence interval p value Gender (male) 2.38 1.138~5.362 ...

Table 5 Cox regression analyses for implant surviv...

  Hazard ratio 95% confidence interval p value Gender (male) 1.99 0.538~8.201 ...

Table 4 Distribution of implants by length and loc...

Dia. (mm) Maxilla anterior Maxilla posterior Mandible anterior Mandible posterior Tot...

Table 3 Distribution of implants by diameter and l...

Dia. (mm) Maxilla anterior Maxilla posterior Mandible anterior Mandible posterior Tot...

Table 2 Distribution of implants in situ (n = 22...

Position 1 2 3 4 5 6 ...

Table 1 Age and gender distributions (n = 92) : ...

Age/gender Male Female Total 20–29 3 ...

About this article : Retrospective cohort study of...

Horikawa, T., Odatsu, T., Itoh, T. et al. Retrospective cohort study of rough-surface titanium implants with at least 25 years’ function. Int J Implant Dent 3, 42 (2017). https://doi.org/10.1186/s40729-017-0101-7 Download citation Received: 26 April 2017 Accepted: 28 August 2017 Published: 05 September 2017 DOI: https://doi.org/10.1186/s40729-017-0101-7

Rights and permissions : Retrospective cohort stud...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Retrospective cohort study o...

Tadashi Horikawa, Tetsurou Odatsu, Takatoshi Itoh, Yoshiki Soejima, Hutoshi Morinaga, Naruyoshi Abe, Naoyuki Tsuchiya, Toshikazu Iijima, and Takashi Sawase declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Retrospective cohort study of...

You can also search for this author in PubMed Google Scholar TH, TO, and TS initiated and designed the retrospective study and drafted the manuscript including the preparation of figures and tables. TH, TAI, YS, HM, NA, NT, and TOI reviewed the medical records and collected the data. All authors revised the manuscript and approved the final manuscript. Correspondence to...

Author information : Retrospective cohort study of...

Kyushu Implant Research Group, 4-14 Kokaihonmachi, Chuo-ku, Kumamoto, 860-0851, Japan Tadashi Horikawa, Takatoshi Itoh, Yoshiki Soejima, Hutoshi Morinaga, Naruyoshi Abe, Naoyuki Tsuchiya, Toshikazu Iijima & Takashi Sawase Department of Applied Prosthodontics, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan Tetsurou Odatsu & Takash...

References : Retrospective cohort study of rough-s...

Pjetursson BE, Thoma D, Jung R, Zwahlen M, Zembic A. A systematic review of the survival and complication rates of implant-supported fixed dental prostheses (FDPs) after a mean observation period of at least 5 years. Clin Oral Implants Res. 2012;23(Suppl 6):22–38. Dorner S, Zeman F, Koller M, Lang R, Handel G, Behr M. Clinical performance of complete dentures: a retrospective study. Int J Prost...

References : Retrospective cohort study of rough-s...

Duda M, Matalon S, Lewinstein I, Harel N, Block J, Ormianer Z. One piece immediately loading implants versus 1 piece or 2 pieces delayed: 3 years outcome. Implant Dent. 2016;25:109–13. Wennerberg A, Albrektsson T. Effects of titanium surface topography on bone integration: a systematic review. Clin Oral Implants Res. 2009;20(Suppl 4):172–84. Teughels W, Van Assche N, Sliepen I, Quirynen M. E...

References : Retrospective cohort study of rough-s...

Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg. 1988;81:672–6. Boyne PJ, James RA. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg. 1980;38:613–6. Hellem S, Karlsson U, Almfeldt I, Brunell G, Hamp SE, Astrand P. Nonsubmerged implants in the treatment of the edentulous lower jaw: a 5-year pro...

References : Retrospective cohort study of rough-s...

Brånemark PI, Adell R, Breine U, Hansson BO, Lindström J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3:81–100. Buser D, Sennerby L, De Bruyn H. Modern implant dentistry based on osseointegration: 50 years of progress, current trends and open questions. Periodontol. 2017;73:7–21. Ekelund JA, Lindquist LW, Carlsson GE, ...

Conclusions : Retrospective cohort study of rough-...

In conclusion, our analyses revealed a cumulative survival rate of 89.8% of TPS-surface implants with at least 25 years of functioning. The survival rate of maxillary positioned implants was significantly lower than that of mandibulary positioned implants. The patient gender, implant location, and width of keratinized mucosa affected the rate of peri-implantitis, resulting in late failure. Implan...

Discussion : Retrospective cohort study of rough-s...

We also observed that the tooth-implant-supported prostheses had a lower complication-free rate than implant-supported fixed prostheses due to caries, periodontitis, or the root fracture of abutment teeth. Lang et al. reported that the survival rates of tooth implant-supported fixed partial dentures were 94.1% after 5 years and 77.8% after 10 years of functioning [31], and these results were alm...

Discussion : Retrospective cohort study of rough-s...

Regarding the width of keratinized mucosa, many studies and a review have indicated that the presence of a sufficient width of keratinized mucosa is necessary for maintaining healthy peri-implants [26,27,28,29]. In the present study, when 2 mm of keratinized mucosa was used as the adequate width, the p value was 0.053 (data not shown). This also showed the tendency of the availability of keratini...

Discussion : Retrospective cohort study of rough-s...

Peri-implantitis is the major reason for late failure [13, 14]. The consensus report of the Sixth European Workshop on Periodontology described peri-implant mucositis in approx. 80% of subjects restored with implant, and peri-implantitis in 28–56% of subjects [15]. In the present study, the cumulative incidence of peri-implantitis was 9.5, 15.3, 21.0, and 27.9% at 5, 10, 15, and 25 years after ...

Discussion : Retrospective cohort study of rough-s...

Although all implants used in this study were withdrawn from the market about 20 years before, the longitudinal clinical outcomes over decades will help to better understand potential factors leading to implant failure or complications and assess the safe and predictable use of dental implant. Our analyses revealed a 25-year cumulative survival rate of 89.8% after the prosthesis setting, which se...

Results : Retrospective cohort study of rough-surf...

A total of 48 implants were eventually accompanied by a peri-implant infection: the cumulative incidence of peri-implantitis was 9.5, 15.3, 21.0, and 27.9% at 5, 10, 15, and 25 years after the prosthesis delivery, respectively (Fig. 3). After stepwise backward selection, the gender, implant type, and width of keratinized mucosa showed the significant difference in the cumulative survival rate (T...

Results : Retrospective cohort study of rough-surf...

A total of 92 patients (38 men, 54 women; mean age 54.3 years, range 20–78) received implant-supported prostheses (at the seven private practices) between 1984 and 1990. The distribution of patients by age and gender is presented in Table 1. Fifty-seven patients (140 implants) were considered dropouts due to the fact that no data were obtained at the endpoint, but 25 years had passed since th...

Methods : Retrospective cohort study of rough-surf...

This retrospective observational study was approved by the ethical committee of Nagasaki University (No. 1512). The cases of all of the patients who underwent dental implant treatment with a TPS-surfaced solid-screw implant and whose prosthesis was set in the years 1984–1990 at seven private practices were analyzed. All inserted implants were either a TPS-type (TPS-type, Institute Straumann, Bas...

Background : Retrospective cohort study of rough-s...

Dental implant treatment based on the concept of osseointegration [1] is now a widely accepted restorative treatment for fully and partially edentulous patients. In the earliest days of the use of osseointegrated implants, two different topographies were applied on the implant surfaces: a machined minimally rough titanium surface such as the Brånemark system and a rough microporous titanium plasm...

Abstract : Retrospective cohort study of rough-sur...

The longitudinal clinical outcomes over decades contribute to know potential factors leading to implant failure or complications and help in the decision of treatment alternatives. The cases of all patients who received dental implants treated with titanium plasma-sprayed surfaces and whose prostheses were set in the period 1984–1990 at seven private practices were retrospectively analyzed. The...

Fig. 3. Example of another case involved in the s...

Fig. 3. Example of another case involved in the study. a Preoperative view –premolars and molars are missing in left mandible. b Preoperative CT scan. The width of the ridge was around 4 mm. c Baseline periapical radiograph. Four narrow diameter implants were placed to restore the area. d Buccal view of the final full-contour zirconia restoration. e Periapical radiograph at 1 year after loa...

Fig. 2. Case 1: Example of one case involved in t...

Fig. 2. Case 1: Example of one case involved in the study. a Preoperative view of a partial edentulism in posterior mandible. b Preoperative CT scan. The width of the ridge was 4 mm. c Four narrow diameter implants were placed and left to a nonsubmerged healing. d Baseline periapical radiograph. e Buccal vieew of the final metal ceramic restoration. f Periapical radiograph at 1 year after loa...

Fig. 1. Characteristics of the implants used in t...

Fig. 1. Characteristics of the implants used in the study: a external macro-design of JDIcon Ultra S, 2.75 mm diameter implant and b external macro-design of JDEvolution S, 3.25 mm diameter implant Fig. 1. Characteristics of the implants used in the study: a external macro-design of JDIcon Ultra S, 2.75 mm diameter implant and b external macro-design of JDEvolution S, 3.25 mm diameter i...

Table 4 Comparison of mean bone levels (means ±...

Diameter 2.75 mm    Follow-up Mean bone level changes (mm) (n = 69) 0–6 months (95% CI) (n = 67) 0–12 months (95% CI) (n = 67) ...

Table 3 Comparison of mean bone levels (means ±...

Follow-up Mean bone level (mm) (n = 124) Time 0–6 months (95% CI) (n = 121) 0–12 months (95% CI) (n = 121) ...

Table 2 Dimensions (diameter and length) and final...

Length (mm) 8 18 (14.5%) 10 56 (45.2%) 11.5 ...

Table 1 Features of the subjects included in the s...

Number of patients 42 Males (%) 18 (42.9%) Females (%) 24 (57.1%) ...

About this article : Narrow implants (2.75 and 3.2...

Grandi, T., Svezia, L. & Grandi, G. Narrow implants (2.75 and 3.25 mm diameter) supporting a fixed splinted prostheses in posterior regions of mandible: one-year results from a prospective cohort study. Int J Implant Dent 3, 43 (2017). https://doi.org/10.1186/s40729-017-0102-6 Download citation Received: 23 March 2017 Accepted: 29 August 2017 Published: 08 September 2017 ...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Narrow implants (2.75 and 3....

Tommaso Grandi serves as a consultant for JDentalCare. Luigi Svezia and Giovanni Grandi declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Narrow implants (2.75 and 3.2...

Private practice, Via Contrada 323, 41126, Modena, Italy Tommaso Grandi & Luigi Svezia Department of Obstetrics, Gynecology and Pediatrics, University of Modena and Reggio Emilia, Modena, Italy Giovanni Grandi You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can ...

References : Narrow implants (2.75 and 3.25 mm di...

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References : Narrow implants (2.75 and 3.25 mm di...

Esposito M, Grusovin MG, Maghaireh H, Worthington HV. Interventions for replacing missing teeth: different times for loading dental implants (Review). Cochrane Database Syst Rev. 2013;(3):CD003878. https://doi.org/10.1002/14651858.CD003878.pub5. Esposito M, Grusovin MG, Felice P, Karatzopoulos G, Worthington HV, Coulthard P. The efficacy of horizontal and vertical bone augmentation procedures for...

Conclusions : Narrow implants (2.75 and 3.25 mm d...

Within the limits of this prospective cohort study, narrow-diameter implants (2.75 to 3.25 mm) can be successfully used as a minimally invasive alternative to horizontal bone augmentation in posterior mandible up to 1 year of function. This outcome could be related to the fact that these implants have been all splinted to other implants by a fixed prosthesis. These preliminary results must be co...

Discussion : Narrow implants (2.75 and 3.25 mm di...

On the one hand, due to the small sample size of this study and moreover, the short follow-up (only 1 year after loading), it would be hazardous to conclude that the placement of NDIs to support fixed prostheses in posterior mandible is a predictable treatment modality. In order to draw more reliable conclusions, we need to wait for longer follow-ups, since it may be possible that after several y...

Discussion : Narrow implants (2.75 and 3.25 mm di...

Dental implants with a reduced diameter are commonly used where bone width is narrow or in cases of restricted mesiodistal anatomy such as laterally maxillary and mandibular incisors. They could also be a viable alternative to bone augmentation especially in challenging situations such as the posterior regions of the mandible. While it has been shown that it is possible to horizontally augment bon...

Results : Narrow implants (2.75 and 3.25 mm diame...

The radiographic data are summarized in Tables 3 and 4. The group lost statistically significant marginal peri-implant bone at 6 months (−0.20; 95% C −0.14: −0.26, p 

Results : Narrow implants (2.75 and 3.25 mm diame...

Forty-eight patients were screened for eligibility, but six subjects were not included for the following reasons: five patients (10.4%) were hesitant to receive implant treatment, and one patient (2.1%) was treated with intravenous amino-bisphosphonates. Forty-two patients were then considered eligible and were consecutively enrolled in the study. All patients were treated according to the allocat...

Methods : Narrow implants (2.75 and 3.25 mm diame...

Primary outcome measures were as follows: Implant failure: evaluated as implant mobility and removal of stable implants dictated by progressive marginal bone loss or infection. The stability of each implant was measured manually by tightening the abutment screw with a wrench delivering a torque of 20 Ncm. Implant stability assessment was performed at delivery of definitive crowns (3 months afte...

Methods : Narrow implants (2.75 and 3.25 mm diame...

The present prospective study was conducted at a private practice (Tommaso Grandi, Modena) in Italy between October 2014 and January 2016. Any patient with partial edentulism in posterior regions of mandible (premolar/molar areas), requiring one multiple tooth implant-supported restoration (2-, 3-, or 4-unit bridge), having a residual bone height of at least 8 mm and a thickness of at least 4 m...

Background : Narrow implants (2.75 and 3.25 mm di...

The aim of this cohort study was to evaluate the outcome of narrow-diameter implants (2.75 and 3.25 mm diameter) used as definitive implants in patients with insufficient bone ridge thickness for placing standard-diameter implants in posterior regions of the mandible. The present study reports the clinical outcome up to 1 year after loading. It is planned to follow up this patients’ cohort to ...

Background : Narrow implants (2.75 and 3.25 mm di...

Historically, implants have been used and documented mainly with diameters between 3.7 and 4.3 mm. Employing these diameters for numerous indications, scientifically substantiated treatment protocols with excellent long-term results have been established [1]. One disadvantage of a standard-diameter implant is the fact that, in clinical use, the available horizontal crestal dimensions of the alveo...

Abstract : Narrow implants (2.75 and 3.25 mm diam...

Can multiple splinted narrow-diameter implants be used as definitive implants in patients with insufficient bone ridge thickness in posterior regions of the mandible? With this aim, we evaluated their outcomes in this set up to 1 year after loading. Forty-two patients with a mean age of 61.3 years old (range 49–73) in need of fixed prosthetic implant-supported rehabilitations in the posterior...

Fig. 4. Scatterplot depicting indirect calculated ...

Fig. 4. Scatterplot depicting indirect calculated and direct measured ISQ values of the tested implants Fig. 4. Scatterplot depicting indirect calculated and direct measured ISQ values of the tested implants

Fig. 3. Example of a typical autospectrum pointing...

Fig. 3. Example of a typical autospectrum pointing to a 1 maximum RF based on 1000 measurements in case of a Straumann test implant Fig. 3. Example of a typical autospectrum pointing to a 1 maximum RF based on 1000 measurements in case of a Straumann test implant

Fig. 2. Clamped Osstell probe orientated towards a...

Fig. 2. Clamped Osstell probe orientated towards a Smartpeg mounted on a test implant. Note the red laser beam dot on the flat surface of the Smartpeg hexagon part Fig. 2. Clamped Osstell probe orientated towards a Smartpeg mounted on a test implant. Note the red laser beam dot on the flat surface of the Smartpeg hexagon part

Fig. 1. Concept for study of deflection and stiffn...

Fig. 1. Concept for study of deflection and stiffness aspects of implant-Smartpeg complex by laser Doppler vibrometry. Intentional partial imbedding of implants allows to detect both the deflection of implant and Smartpeg separately at different vertical levels by changing the position of the laser beam Fig. 1. Concept for study of deflection and stiffness aspects of implant-Smartpeg complex ...

Table 2 Mean values (± SD) of recorded maximum ...

Batch # Implant system Implant length (mm) Implant diameter (mm) Mean measured resonance freq (kHz) SD meas...

Table 1 Published secondary implant stability valu...

Author and study Implant position (implant number) Mean ISQ values at given time-point post-insertion Type of Osstell device used Barewal et al. 2003 [10] ...

About this article : ISQ calculation evaluation of...

Debruyne, S., Grognard, N., Verleye, G. et al. ISQ calculation evaluation of in vitro laser scanning vibrometry-captured resonance frequency. Int J Implant Dent 3, 44 (2017). https://doi.org/10.1186/s40729-017-0105-3 Download citation Received: 11 April 2017 Accepted: 28 September 2017 Published: 12 October 2017 DOI: https://doi.org/10.1186/s40729-017-0105-3

Rights and permissions : ISQ calculation evaluatio...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : ISQ calculation evaluation o...

Stijn Debruyne, Nicolas Grognard, Gino Verleye, Korneel Van Massenhove, Dimitrios Mavreas, and Bart Vande Vannet declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : ISQ calculation evaluation of...

Correspondence to Nicolas Grognard.

Author information : ISQ calculation evaluation of...

Department of Mechanics, Research Group Propolis, School of Engeneering Sciences, Katholieke Hoge School Brugge-Oostende, Ostend, Belgium Stijn Debruyne Kliniek Royal, Koningstraat 41, 8400, Ostend, Belgium Nicolas Grognard CHIR-Unit Dentistry–ORHE, Department of Orthodontics, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium Nicolas Gro...

References : ISQ calculation evaluation of in vitr...

Han J, Lulic M, Lang NP. Factors influencing resonance frequency analyis assessed by Osstell Mentor during implant issue integration: II: implant surface modifications and implant diameter. Clin Oral Implants Res. 2010;6:605–11. Bornstein M, Hart C, Halbritter S, Morton D, Buser D. Early loading of nonsubmerged titanium implants with a chemically modified sand-blasted and acid-etched surface: 6...

References : ISQ calculation evaluation of in vitr...

Adell R, Lekholm U, Brånemark PI. Surgical procedures. In: Brånemark PI, Zarb GA, Albrektsson T, editors. Tissue integrated prothese. Osseointegration in clinical dentistry. Chigaco: Quintessence; 1985. p. 211–32. Strid K. Radiographic procedures. In: Brånemark P-I, Zarb G, Albrektsson T, editors. Tissue integrated prothese. Osseointegration in clinical dentistry. Chigaco: Quintessence; 1985...

Conclusions : ISQ calculation evaluation of in vit...

In conclusion, the present study demonstrated that the algorithm applied and provided by Osstell to calculate ISQ values is correct, making the laboratory procedure valuable for future research focused on stiffness aspects of the implant-Smartpeg complex and its possible influence on the overall RFA measurement. Vice versa, the present study demonstrates the correctness of the actual applied algor...

Discussion : ISQ calculation evaluation of in vitr...

The focus of this in vitro study was to develop a laboratory method, intended for future research of aspects of implant-Smartpeg complex stiffness and its possible influence on the overall RFA-based implant stability determination. In the past, other laboratory methodologies have been engineered to investigate implant deflection and/or lateral displacement by means of transducers. A setup using a ...

Results : ISQ calculation evaluation of in vitro l...

Mean values (± SD) of recorded maximum RF values, calculated indirect ISQ values, and direct recorded ISQ values for Ankylos (A) and Straumann (S) test implants are shown in Table 2. Using the Shapiro-Wilk test for indirect ISQ (p = 0.05) and direct ISQ (p = 0.02), we can conclude that both indirect and direct ISQ measures are not drawn from a normal distribution (data not shown). Bot...

Methods : ISQ calculation evaluation of in vitro l...

In total, for each given implant type with a given diameter/length configuration, 25 measurements for indirect and 5 measurements for direct ISQ computing were performed. The SPSS statistical software package 22.0 (IBM SPSS, Chicago, USA) was used. A Shapiro-Wilk test was used to verify distribution normality for both direct and indirect determined ISQ values. The paired sample t test and the Wil...

Methods : ISQ calculation evaluation of in vitro l...

The Smartpeg excitation mode was exactly performed as described above. Notation of the maximum resonance frequency for indirect measurements is followed by notation of direct ISQ value on the display of Osstell IDx device. Positioning of the probe was not changed during indirect and direct recordings for a given test implant. Each resin block contained five identical implants with attached Smartp...

Methods : ISQ calculation evaluation of in vitro l...

Test implants originating from various manufacturers were investigated. Straumann sandblasted, large-grit, acid-etched (SLA)® tissue level standard implants (Straumann AG, Basel, Switzerland) with the following diameter: length configurations were 3.3–12 mm (RN connection), 3.3–4.1 mm (RN connection), and 4.8–8 mm (WN connection), Ankylos Cell Plus® surfaced B-implant types (Dentsply Im...

Background : ISQ calculation evaluation of in vitr...

Laser Doppler vibrometry possesses a working principle based on the so-called Doppler effect and allows non-contact quantitative measurement of vibration (https://en.wikpedia.org/wiki/Laser_scanning_vibrometry, 2017). The Doppler effect itself finds its origin when a light beam is backscattered on a vibrating surface and experiences a change in wave phase (https://en.wikipedia.org/wiki/Doppler_eff...

Background : ISQ calculation evaluation of in vitr...

The computed ISQ value is based on the following calculation formulae: Hereby, f denotes the measured maximum resonance frequency (RF). Coefficients a, b, c, d, and e are property information of Osstell (Osstell AB, Gothenburg, Sweden). The coefficients were provided for internal use under the agreement of no publication. From clinical reports [10,11,12,13,14,15,16] listed in Table 1, it ...

Background : ISQ calculation evaluation of in vitr...

At present, multiple implant stability assessment methodologies are used, both of invasive and non-invasive nature, including percussion test [1], X-ray evaluation [2], cutting resistance during implant insertion (e.g., electronic insertion torque determination) [3], turn-out or reverse torque test [4], Periotest® [5, 6], and resonance frequency analysis (“RFA”), e.g., the Osstell method [7, ...

Abstract : ISQ calculation evaluation of in vitro ...

Implant stability testing at various stages of implant therapy by means of resonance frequency analysis is extensively used. The overall measurement outcome is a function of the resulting stiffness of three entities: surrounding bone, bone-implant complex, and implant-Smartpeg complex. The influence of the latter on the overall measurement results is presently unknown. It can be investigated in vi...

Table 6 Correlations between PPD and the other par...

Parameters H group correlation (R s ) HP group correlation (R s ) PPD-mPI 0.182 n.s. ...

Table 5 Correlations between PPD and characteristi...

Characteristics H group correlation (R s ) HP group correlation (R s ) Age 0.040 n.s. 0.209* Number of teeth (at the beginning o...

Table 4 Value of each clinical parameter : Correla...

Clinical parameters H group (n = 39) mean ± SD/median HP group (n = 91) mean ± SD/median Significance difference between H and HP group ...

Table 3 Prevalence of peri-implantitis and periodo...

Diagnosis in HP group (37 patients, 91 implants) Localized: ≤ 30% of site involved, generalized: > 30% of site involved Numbers of peri-implantitis and prevalence in diagnosis n = 14, 15.4% of HP group ...

Table 2 Characteristics of the study population : ...

  H group mean ± SD, or n (median) HP group mean ± SD, or n (median) Significant difference between H and HP group Age 56.0 ± 11.8 (57.9) ...

Table 1 Implant systems used : Correlations betwee...

Implant Number Replace select ™ 44 Novel Replace ® 31 ...

About this article : Correlations between clinical...

Seki, K., Nakabayashi, S., Tanabe, N. et al. Correlations between clinical parameters in implant maintenance patients: analysis among healthy and history-of-periodontitis groups. Int J Implant Dent 3, 45 (2017). https://doi.org/10.1186/s40729-017-0108-0 Download citation Received: 25 July 2017 Accepted: 19 October 2017 Published: 30 October 2017 DOI: https://doi.org/10.11...

Rights and permissions : Correlations between clin...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Correlations between clinica...

Patient recruitment and data collection for this study took place at Nihon University School of Dentistry Dental Hospital, Japan. The research was approved by the Nihon University School of Dentistry Ethics Committee (2013-15) and all activities were conducted in full accordance with ethical principles, including the World Medical Association Declaration of Helsinki. We described the purpose of th...

Author information : Correlations between clinical...

Implant Dentistry, Nihon University School of Dentistry Dental Hospital, Tokyo, 101-8310, Japan Keisuke Seki, Shinya Nakabayashi, Atsushi Kamimoto & Yoshiyuki Hagiwara Department of Comprehensive Dentistry and Clinical Education, Nihon University School of Dentistry, 1-8-13 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8310, Japan Keisuke Seki & Atsushi Kamimoto Department of Applied Mathemati...

References : Correlations between clinical paramet...

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References : Correlations between clinical paramet...

Karousis IK, Salvi GE, Heitz-Mayfield LJ, Brägger U, Hämmerle CH, Lang NP. Long-term implant prognosis in patients with and without a history of chronic periodontitis: a 10-year prospective cohort study of the ITI Dental Implant System. Clin Oral Implants Res. 2003;14:329–39. Mengel R, Flores-de-Jacoby L. Implants in patients treated for generalized aggressive and chronic periodontitis: a 3-y...

References : Correlations between clinical paramet...

Monjie A, Aranda L, Diaz KT, Alarcón MA, Bagramian RA, Wang HL, et al. Impact of maintenance therapy for the prevention of peri-implant diseases: a systematic review and meta-analysis. J Dent Res. 2016;95:372–9. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol. 1999;4:1–6. Lang NP, Berglundh T; Working group 4 of Seventh European W...

References : Correlations between clinical paramet...

Esposito M, Hirsch JM, Lekholm U, Thomsen P. Biological factors contributing to failures of osseointegrated oral implants. (I) Success criteria and epidemiology. Eur J Oral Sci. 1998;106:527–51. Ogata Y, Nakayama Y, Tatsumi J, Kubota T, Sato S, Nishida T, et al. Prevalence and risk factors for peri-implant diseases in Japanese adult dental patients. J Oral Sci. 2017;59:1–11. Heitz-Mayfield L...

Abbreviations : Correlations between clinical para...

Bleeding on probing Modified plaque index Probing pocket depth

Conclusions : Correlations between clinical parame...

We examined clinical parameters in patients receiving long-term implant maintenance. There were significant differences between the H and HP groups in age at the time of maintenance, number of natural teeth at the beginning of implant treatment, total number of extracted teeth, and maintenance. The prevalence of implant-based peri-implantitis was 10.8% of all the implants. All implants with peri-i...

Discussion : Correlations between clinical paramet...

A correlation between the PPD of the peri-implant tissue and lesion progression has been reported, similar to that seen with periodontitis [27]. Probing around the implant is useful for evaluating soft tissue inflammation and is considered reproducible [36]. Examination of peri-implant bleeding is reported to have higher diagnostic accuracy than probing around natural teeth [37]. However, because ...

Discussion : Correlations between clinical paramet...

BoP has been used to evaluate inflammatory conditions of periodontal tissue [33] and can also be an important evaluation item for peri-implant tissues. To avoid diagnosing bleeding resulting from strong probing as a false positive, we set the probing pressure to 0.15 N [34]. BoP values were low, with no significant difference between the groups (H group, 0.30; HP group, 0.28). This result was sim...

Discussion : Correlations between clinical paramet...

All the implants with peri-implantitis came from the HP group, not the H group, thus supporting the view that a history of periodontitis is a risk indicator for peri-implantitis. In the diagnosis of periodontitis within the HP group, it is notable that peri-implantitis increased as periodontitis become more severe. This supports the findings of a previous study that reported that the survival rate...

Discussion : Correlations between clinical paramet...

In this study, we reviewed the clinical parameters of 130 implants in 55 patients during ongoing long-term maintenance. We focused on the history of periodontitis and compared the parameters in two groups classified according to a history of periodontitis. A previous study on the prevalence of periodontitis revealed that moderate or severe periodontitis was observed in 64% of people over 65 years...

Results : Correlations between clinical parameters...

Because normality and homoscedasticity were not obtained for each clinical parameter between the two groups, a statistical study was conducted using the nonparametric test (Mann–Whitney U test) for the difference test between the two groups. PPD was recognized to be significantly greater (p 

Results : Correlations between clinical parameters...

Of the 55 subjects, 25 were male and 30 were female (H group: 8/10, HP group: 17/20, respectively). A total of 130 implants (H group 39, HP group 91) were included in the analysis (Table 2). The mean maintenance period was 6 years and 6 months. The average number of natural teeth at the first visit and at the beginning of implant treatment were 25.3 ± 2.9 and 22.4 ± 4.5, respectively. Com...

Methods : Correlations between clinical parameters...

At the time of optional maintenance, the following parameters were measured for each implant. Data collection and analysis were conducted by two operators who were blind to the research purpose and methods. One operator statistically analyzed the final data set. Plaque adhesion (modified Plaque Index: mPI) on the superstructure of the implant was measured on a 4-point scale (0, no plaque; 1, plaq...

Methods : Correlations between clinical parameters...

This study enrolled 55 patients (25 men, 30 women; mean age, 63.53 ± 10.51 years) who visited Nihon University School of Dentistry Dental Hospital for implant maintenance from April to September 2016. The inclusion criteria were treatment at the same hospital with two-stage implant placement before 2015, and ongoing maintenance at 3–6-month intervals after superstructure placement. Patients ...

Background : Correlations between clinical paramet...

Peri-implant diseases are the main biological complication of implant treatment and greatly influence treatment success [1]. Risk indicators for peri-implantitis include a history of periodontitis, poor oral hygiene, and smoking [2,3,4]. Peri-implantitis is often encountered clinically, occurring in 12 to 43% of implants and 28 to 47% of implant patients [5,6,7,8]. Similarities between the patholo...

Abstract : Correlations between clinical parameter...

The pathophysiology and pathology of peri-implantitis remain unclear; however, its similarity to periodontitis has been described. The evaluation of peri-implant tissue and the diagnostic criteria of peri-implant disease are not currently standardized as they are for periodontitis. In this study, we evaluated clinical parameters during the implant maintenance period to determine significant correl...

Fig. 5. a Postoperative orthopantomogram. b Follow...

Fig. 5. a Postoperative orthopantomogram. b Follow-up orthopantomogram. c Follow-up standard periapical radiogram (implants i42 and i44). d Follow-up standard periapical radiogram (implants i32 and i34) Fig. 5. a Postoperative orthopantomogram. b Follow-up orthopantomogram. c Follow-up standard periapical radiogram (implants i42 and i44). d Follow-up standard periapical radiogram (implants i3...

Fig. 4. a–h Prosthetic restauration—follow-up ...

Fig. 4. n. Intraoral and perioral views of a rehabilitated female patient. (She asked explicitly only for implantological treatment in the mandible.) Fig. 4. a–h Prosthetic restauration—follow-up examination. Intraoral and perioral views of a rehabilitated female patient. (She asked explicitly only for implantological treatment in the mandible.)

Fig. 3. a Primary implant stability. The histogram...

Fig. 3. by resonance frequency analysis (Osstell AB, Göteborg, Sweden). b Secondary implant stability. The histogram shows the distribution of the implant stability quotients (ISQ) of osseointegrated implants. According to the measurement implant stability was classified as low with ISQ values  70 [34] Fig. 3. a Primary implant stability. The histogram visualises the distribution of the im...

Fig. 2. Cumulative implant survival over the follo...

Fig. 2. Cumulative implant survival over the follow-up period. The Kaplan-Meyer diagram visualises the analysis of implant survival in the maxilla and in the mandible (log rank test, p = 0.173) over the follow-up period up to 37 months (Table 4) Fig. 2. Cumulative implant survival over the follow-up period. The Kaplan-Meyer diagram visualises the analysis of implant survival in the maxi...

Fig. 1. a Closed short expandable dental implant (...

Fig. 1. e implant-abutment connection is characterised by an internal hexagon for rotation stability, combining the advantages of conical and parallel surfaces to reduce microgaps and micromovement [68]. The microthread concept and platform switching concept are implemented in the implant shoulder to reduce periimplant bone strain [53]. b Manual fixation of the expansion tool. Take note of the ...

Table 4 Clinical characteristics of the study coho...

Patient Sex Age (years) Implant position (FDI) Indication categorya Bone quality Prosthetic treatment ...

Table 3 Prosthetic treatment protocol : Novel expa...

Type of prosthetic treatment Session Procedure Fixed denture (bridge) 1 Open impression ...

Table 2 Surgical treatment protocol : Novel expand...

Surgical protocol Bone quality   D1 D2 D3 D4 1. Drilli...

Table 1 Patient recruitment : Novel expandable sho...

Inclusion criteria Exclusion criteria 1. Adult patients, male and female 1. Comorbidity ASA category ≥ III 2. Partially/totally edentulous patients ...

About this article : Novel expandable short dental...

Reich, W., Schweyen, R., Heinzelmann, C. et al. Novel expandable short dental implants in situations with reduced vertical bone height—technical note and first results. Int J Implant Dent 3, 46 (2017). https://doi.org/10.1186/s40729-017-0107-1 Download citation Received: 18 August 2017 Accepted: 12 October 2017 Published: 30 October 2017 DOI: https://doi.org/10.1186/s40...

Rights and permissions : Novel expandable short de...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional files : Novel expandable short dental i...

Dataset presenting relevant raw data. (SAV 3 kb)

Ethics declarations : Novel expandable short denta...

WR is a senior physician at the University Hospital Halle, Martin Luther University Halle-Wittenberg, Department of Oral and Plastic Maxillofacial Surgery, Halle/Saale, Germany. RS is a clinical research associate at the University School of Dental Medicine, Department of Prosthetic Dentistry, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany. CH is a consultant at the University H...

Author information : Novel expandable short dental...

Correspondence to Waldemar Reich.

Author information : Novel expandable short dental...

Department of Oral and Plastic Maxillofacial Surgery, Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle (Saale), Germany Waldemar Reich, Christian Heinzelmann, Bilal Al-Nawas & Alexander Walter Eckert University School of Dental Medicine, Department of Prosthetic Dentistry, Martin Luther University Halle-Wittenberg, Magdeburger Straße 16, 06112, Halle (Saale), Ger...

Acknowledgements : Novel expandable short dental i...

The authors are grateful to the DenTack Company for providing some of the implants and components used in this study. The courtesy of Oz Vachtenberg is acknowledged for providing Fig. 1a–f and the movie clip. There are no financial supports or conflicts of interest associated with this publication that could have influenced its outcome. We thank the Osstell Company, which supplied the RFA devic...

References : Novel expandable short dental implant...

Mishra SK, Chowdhary R, Kumari S. Microleakage at different implant abutment interface: a systematic review. J Clin Diagn Res. 2017;11(6):ZE10–5. Feichtinger M, Gaggl A, SChultes G, Kärcher H. Evaluation of distraction implants for prosthetic treatment after vertical alveolar ridge distraction: a clinical investigation. Int J Prosthodont. 2003;16(1):19–24. Pradeep PR, Kasti KJ, Ananthakrish...

References : Novel expandable short dental implant...

Gehrke SA, Pérez-Albacete Martinez C, Piattelli A, Shibli JA, Markovic A, Calvo Guirado JL. The influence of three different apical implant designs at stability and osseointegration process: experimental study in rabbits. Clin Oral Implants Res. 2017;28(3):355–61. Herrero-Climent M, Santos-Garcia R, Jaramillo-Santos R, Romero-Ruiz MM, Fernandez-Palacin Lazaro-Calvo P, Bullon P, Rios-Santos JV....

References : Novel expandable short dental implant...

Malmstrom H, Gupta B, Ghanem A, Cacciato R, Ren Y, Romanos GE. Success rate of short dental implants supporting single crowns and fixed bridges. Clin Oral Implants Res. 2016;27(9):1093–8. Garfield RE. An expandable implant fixture. Dent Implantol Updat. 1998;9(5):37–40. Nowzari H, Chee W, Tuan A, Abou-Rass M, Landesman HM. Clinical and microbiological aspects of the Sargon immediate load imp...

References : Novel expandable short dental implant...

Brenner M, Brandt J, Lauer HC. Prothetische Versorgung auf kurzen Implantaten. Zahnmedizin up2date. 2014;2:123–42. (German) Eitner S, Wichmann M, Schlegel KA, Kollmannberger JE, Nickenig HJ. Oral health-related quality of life and implant therapy: an evaluation of preoperative, intermediate, and post-treatment assessments of patients and physicians. J Craniomaxillofac Surg. 2012;40(1):20–3. ...

References : Novel expandable short dental implant...

De Moraes SL, Verri FR, Santiago JF Jr, Almeida DA, de Mello CC, Pellizzer EP. A 3-D finite element study of the influence of crown-implant ratio on stress distribution. Braz Dent J. 2013;24(6):635–41. Moraes SL, Pellizzer EP, Verri FR, Santiago JF Jr, Silva JV. Three-dimensional finite element analysis on stress distribution in retention screws of different crown-implant ratios. Comput Methods...

References : Novel expandable short dental implant...

Thoma DS, Haas R, Tutak M, Garcia A, Schincaglia GP, Hämmerle CH. Randomised controlled multicenter study comparing short dental implants (6 mm) versus longer dental implants (11-15 mm) in combination with sinus floor elevation procedures. Part 1: demographic and patient-reported outcomes at 1 year of loading. J Clin Periodontol. 2015;42(1):72–80. Hentschel A, Herrmann J, Glauche I, Vollmer A,...

References : Novel expandable short dental implant...

Schwarz F, Terheyden H. Significance of dental implants for health care. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011;54(9):1097–101. (German) Gates WD, Cooper LF, Sanders AE, Reside GJ, De Kok IJ. The effect of implant-supported removable partial dentures on oral health quality of life. Clin Oral Impl Res. 2014;25:207–13. Fretwurst T, Nack C, Al-Ghrairi M, Raguse JD, ...

Abbreviations : Novel expandable short dental impl...

Bone quality (density) World Dental Federation Implant stability quotient Resonance frequency analysis

Conclusion : Novel expandable short dental implant...

Initial results of the ongoing study confirm the feasibility and safety of the employed system. The implant type seems to be useful for all bone qualities and shows high initial and secondary biomechanical stability in the maxilla and mandible. Long-term follow-up will be needed in validating these initial results in a larger 3-year clinical trial. Crestal bone changes should be evaluated in a la...

Discussion : Novel expandable short dental implant...

Comparable studies displayed at 24 months a crestal bone loss of 0.5–0.6 mm [15]. Other authors reported at 2, 3 and 5 years a mean loss of 0.57, 0.55 and 0.53 mm, respectively, in the mandible (without significant change after 1 year) [10]. On the other hand, randomised controlled trials demonstrated 1 year after loading periimplant marginal bone loss of 0.7 mm [70] and 1.1 mm [7] in th...

Discussion : Novel expandable short dental implant...

Contrary to conventional hollow-screw implants (only marginal gap), a problem of the expandable implant is the presence of gaps down to the apical region. Former microbial assessment of different implant-abutment interfaces displayed that none of the marginal connections had the capacity to prevent microbial leakage [63,64,65]. Therefore, an apical microleakage (comparable to distractable implants...

Discussion : Novel expandable short dental implant...

Regarding resonance frequency analysis, the values are related to bone quality and quantity as well as the exposed implant height above the alveolar crest, which depends on the type of implant and insertion technique [55,56,57]. Our results (primary stability in the maxilla 66.9 ± 8.9 ISQ units and in the mandible 72.5 ± 11.1 ISQ units; secondary stability in the maxilla 66.4 ± 10.0...

Discussion : Novel expandable short dental implant...

Several investigators analysed the preferred indications of short dental implants in the posterior mandible or maxilla and outlined the cost efficiency compared to additional vertical augmentations. In the present trial, we used a new short implant in both jaws and nearly all possible indication categories were represented, which proves the broad versatility (Table 4). In our study, two implant ...

Discussion : Novel expandable short dental implant...

Recent literature has shown that short implants have achieved growing acceptance in the field of oral implantology [9, 10, 39, 40]. Since the last years, concern has decreased about the length of endosseous implants; it should be noted that all extraoral screw implants are short implants [41, 42]. Nevertheless, there are local physiological and biomechanical differences regarding long-term stabili...

Results : Novel expandable short dental implants i...

Over the follow-up period, the mean crestal bone changes after loading were as follows (each compared to the baseline): in the first year, 1.0 ± 0.9 mm 95% CI (0.5; 1.5) in the maxilla and 0.7 ± 0.4 mm 95% CI (0.5; 1.0) in the mandible (p = 0.011; independent t test), and in the second year, 1.3 ± 0.8 mm 95% CI (0.8; 1.7) in the maxilla and 1.0 ± 0.7 mm 95% CI (0.6; 1.4...

Results : Novel expandable short dental implants i...

The first results of this longitudinal study include data from 9 patients with an average age of 57 years (range from 44 to 80) in whom 30 implants were inserted (maxilla n = 15, mandible n = 15). All 30 implants in the 9 patients could be inserted without intraoperative problems. Based on intraoperative and radiological findings, the bone quality was assessed as follows: D1 in n = 2,...

Material and methods : Novel expandable short dent...

All patients were pseudonymised, parameters were attached to a databank and analysed statistically (Additional file 2). Statistical analyses were performed using statistics software (IBM SPSS statistics, version 20, Chicago, IL, USA). The descriptive statistics presented the frequency and distribution of several occurrences as well as combinations of certain features. Analytical statistics were p...

Material and methods : Novel expandable short dent...

Simulation of the expansion process. At the end of the expansion process, a minimal snap back is realised. (MP4 9407 kb) Planning of the implantological treatment followed usual clinical and radiological examination and, concerning the position and number of implants, the recommended categories from the German consensus conference [35]. The drilling sequence, condensing preparation (where necess...

Material and methods : Novel expandable short dent...

The study was designed as a prospective monocentric longitudinal cohort study according to the STROBE criteria. The participants of this study were recruited at the university hospital of Martin Luther University Halle-Wittenberg, Department of Oral and Plastic Maxillofacial Surgery, implantological consultation from 2014 (June) until 2015 (June). Inclusion and exclusion criteria of adult patients...

Introduction : Novel expandable short dental impla...

It is known that achievement of primary stability is one precondition for osseointegration and treatment success. There are few reports of immediate [14] and early (6 weeks) functional loading of short implants [28]. This is related to good bone quality, implant design or implant site preparation (e.g. under-drilling). However, under-drilling of the crestal aspect may lead to decreased bone-to-im...

Introduction : Novel expandable short dental impla...

Endosseous implants have been established over several decades. The evaluation of treatment results under biomechanical, physiological, psychological, social and economic aspects has been well documented [1]. Furthermore, patient-based outcomes reveal a predictable gain in oral health-related quality of life [2]. Especially in patients with limited vertical bone height, process of treatment is ex...

Abstract : Novel expandable short dental implants ...

Short implants often have the disadvantage of reduced primary stability. The present study was conducted to evaluate the feasibility and safety of a new expandable short dental implant system intended to increase primary stability. As a “proof of concept”, a prospective clinical cohort study was designed to investigate intraoperative handling, primary and secondary implant stability (resonanc...

Fig. 6. Postoperative intraoral finding and radiog...

Fig. 6. Postoperative intraoral finding and radiograph Fig. 6. Postoperative intraoral finding and radiograph

Fig. 5. High p53, p63, and Ki-67 reactivity are al...

Fig. 5. High p53, p63, and Ki-67 reactivity are also observed in the basal cell layer (immunohistological staining, bar 400 μm) Fig. 5. High p53, p63, and Ki-67 reactivity are also observed in the basal cell layer (immunohistological staining, bar 400 μm)

Fig. 4. Immunohistological findings show a negativ...

Fig. 4. Immunohistological findings show a negative staining mosaic pattern for keratin 13 (k13) and positive staining for keratin 17 (k17) (immunohistological staining, bar 400 μm) Fig. 4. Immunohistological findings show a negative staining mosaic pattern for keratin 13 (k13) and positive staining for keratin 17 (k17) (immunohistological staining, bar 400 μm)

Fig. 3. Pathological microscopic examination revea...

Fig. 3. Pathological microscopic examination reveals thickened squamous epithelia with slight nuclear atypism and disorders of the epithelial rete pegs accompanied by moderate grade inflammatory cell infiltration (HE staining, bar: 400 μm) Fig. 3. Pathological microscopic examination reveals thickened squamous epithelia with slight nuclear atypism and disorders of the epithelial rete pegs a...

Fig. 2. Panoramic radiograph shows slight vertical...

Fig. 2. Panoramic radiograph shows slight vertical bone resorption around the implants in the right side of the mandible Fig. 2. Panoramic radiograph shows slight vertical bone resorption around the implants in the right side of the mandible

Fig. 1. Well-circumscribed gingival swelling on th...

Fig. 1. Well-circumscribed gingival swelling on the lingual side of the right side of the mandible Fig. 1. Well-circumscribed gingival swelling on the lingual side of the right side of the mandible

Table 1 Summary of immunohistochemical findings of...

Antibody Sorce Clone Staining Keratin 13 DAKO DE-K13 ...

About this article : Primary peri-implant oral int...

Noguchi, M., Tsuno, H., Ishizaka, R. et al. Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis. Int J Implant Dent 3, 47 (2017). https://doi.org/10.1186/s40729-017-0109-z Download citation Received: 15 March 2017 Accepted: 25 October 2017 Published: 16 November 2017 DOI: https://doi.org/10.1186...

Rights and permissions : Primary peri-implant oral...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Primary peri-implant oral in...

Written informed consent was obtained from the patient for publication of this case report and any accompanying images. Makoto Nogchi, Hiroaki Tsuno, Risa Ishizaka, Kumiko Fujiwara, Shuichi Imaue, and Kei Tomihara declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Primary peri-implant oral int...

Correspondence to Makoto Noguchi.

Author information : Primary peri-implant oral int...

Department of Oral and Maxillofacial Surgery, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, 2630 Sugitani Toyama city, Toyama, 9300194, Japan Makoto Noguchi, Hiroaki Tsuno, Risa Ishizaka, Kumiko Fujiwara, Shuichi Imaue & Kei Tomihara Department of Diagnosis Pathology, Graduate School of Medicine and Pharmaceutical Sciences for Research, Univers...

References : Primary peri-implant oral intra-epith...

Vasilescu F, Ceauşu M, Tänsen C, et al. P53, p63 and ki-67 assessment in HPV-induced cervical neoplasia. RJME. 2009;50:357–61. Ndiaye C, Mena M, Alemany L, et al. HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis. Lancet Oncol. 2014;15:1319–31. Nagy K, Sonkodi I, Szöke I, et al. The microflora associated with human oral carcinoma. ...

References : Primary peri-implant oral intra-epith...

Sah JP, Johnson NW, Batsakis JG. Oral cancer. London: Informa Healthcare; 2011. p. 3–32. Japan Society for Oral Tumors. General rules for clinical and pathological studies on oral cancer. 1st ed. Tokyo: Kanehara-shuppan Co; 2010. p. 44–7. Laprise C, Shahl HP, Madathil SA, et al. Periodontal diseases and risk of oral cancer in Southern India: results from the HeNCe Life Study. Int J Cancer. 2...

Abbreviations : Primary peri-implant oral intra-ep...

Deoxyribonucleic acid Human papilloma virus Oral intra-epithelial neoplasia/carcinoma in situ Squamous cell carcinoma

Conclusions : Primary peri-implant oral intra-epit...

In our case, the persistence of peri-implant mucositis or peri-implantitis around the dental implant was implicated as being a plausible risk factor for carcinogenesis. Regular follow-up to ensure the maintenance of oral hygiene after dental implant therapy has again been shown to be important for preventing peri-implantitis, a plausible risk factor for carcinogenesis.

Case presentation : Primary peri-implant oral intr...

The latest evidence implies that the human papilloma virus (HPV) may be responsible for carcinogenesis in the oral cavity [12, 13]; however, its role is debatable. The interaction of the HPV’s E6 and E7 oncoproteins with cell cycle proteins disturbs the cell cycle mechanism and subsequent alteration in the expression of proteins such as p53, p63, and Ki-67 [14]. In our case, the immunohistochemi...

Case presentation : Primary peri-implant oral intr...

OIN/CIS can sometimes be difficult to distinguish pathologically from epithelial dysplasia on hematoxylin- and eosin-staining sections; this has proved challenging for oral pathologists [9]. Recently, it has been reported that combined immunohistochemistry for k13 and k17 was useful for the differential diagnosis [9, 10]. K13 is a marker for cellular differentiation toward prickle cells in normal ...

Case presentation : Primary peri-implant oral intr...

A 65-year-old woman was referred to our clinic with a tumor in the right lower gingiva. Her medical history included breast cancer without metastatic lesion, diabetes mellitus, hyperlipidemia, and hypertension. She had taken orally aspirin, amlodipine, pravastatin, and bepotastine for 2 years. She drank alcohol socially, but she had no history of tobacco smoking habit. About 10 years prior to h...

Background : Primary peri-implant oral intra-epith...

Oral cancer ranks sixth among the malignancies in terms of worldwide prevalence, with more than 90% being pathologically squamous cell carcinoma (SCC) [1]. Oral SCC generally develops via multistep carcinogenesis. The squamous epithelium goes into irreversible change, including epithelial dysplasia and oral intra-epithelial neoplasia/carcinoma in-situ (OIN/CIS) [2], finally resulting in the develo...

Abstract : Primary peri-implant oral intra-epithel...

In this case, prolonged peri-implant mucositis or peri-implantitis may have been a plausible risk factor for carcinogenesis.

Abstract : Primary peri-implant oral intra-epithel...

Major risk factors for oral squamous cell carcinoma (SCC) are tobacco smoking, a betel quid chewing habit, and heavy alcohol consumption. However, around 15% of oral SCCs cannot be explained by these risk factors. Although oral SCC associated with dental implants is quite rare, there has been a recent gradual accumulation of reports about it. Here, we report a case of primary peri-implant oral int...

Table 5 Implant failure rates : Mucositis, peri-im...

  Failure rate n Univariate analyses Multivariate analyses OR (95% CI) P OR ...

Table 4 Risk factors for peri-implantitis : Mucosi...

  Peri-implantitis n Univariate analyses Multivariate analyses   OR (95% CI) P ...

Table 3 Risk factors for mucositis : Mucositis, pe...

  Mucositis n Univariate analyses Multivariate analyses OR (95% CI) P OR ...

Table 2 Observation period (patient and implant re...

Years Patients (total) GCP patients GAP patients Implants (total) Implants maxilla ...

Table 1 Implants in study population : Mucositis, ...

  GCP GAP Patient 24 5 Sex ...

About this article : Mucositis, peri-implantitis, ...

Mengel, R., Heim, T. & Thöne-Mühling, M. Mucositis, peri-implantitis, and survival and success rates of oxide-coated implants in patients treated for periodontitis 3- to 6-year results of a case-series study. Int J Implant Dent 3, 48 (2017). https://doi.org/10.1186/s40729-017-0110-6 Download citation Received: 29 August 2017 Accepted: 26 October 2017 Published: 28 Novemb...

Rights and permissions : Mucositis, peri-implantit...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Mucositis, peri-implantitis,...

RM is a professor at the Department of Prosthetic Dentistry, School of Dental Medicine, Philipps-University, Marburg/Lahn, Germany. TH is a private practicioner in Gruben, Brandenburg, Germany. MT is a researcher at the Department of Prosthetic Dentistry, School of Dental Medicine, Philipps-University, Marburg/Lahn, Germany. This clinical study was conducted in accordance with the World Medical A...

Author information : Mucositis, peri-implantitis, ...

Department of Prosthetic Dentistry, School of Dental Medicine, Philipps-University, Marburg/Lahn, Germany Reiner Mengel & Miriam Thöne-Mühling Gruben, Brandenburg, Germany Theresa Heim You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this au...

References : Mucositis, peri-implantitis, and surv...

Kim K-K, Sung H-M. Outcomes of dental implant treatment in patients with generalized aggressive periodontitis: a systematic review. J Adv Prosthodont. 2012;4:210–7. Pettersson K, Mengel R. Comments on the statistical analysis of the paper by Albouy et al comparing four different types of implants with respect to ‘spontaneous’ progression of peri-implantitis. Eur J Oral Implantol. 2011;1:9...

References : Mucositis, peri-implantitis, and surv...

Kinane DF, Radvar M. The effect of smoking on mechanical and antimicrobial periodontal therapy. J Periodontol. 1997;69:467–72. Swierkot K, Lottholz P, Flores-de-Jacoby L, Mengel R. Mucositis, peri-implantitis, implant success, and survival of implants in patients with treated generalized aggressive periodontitis: 3- to 16-year results of a prospective long-term cohort study. J Periodontol. 2012...

References : Mucositis, peri-implantitis, and surv...

Jungner M, Lundqvist P, Lundgren S. A retrospective comparison of oxidized and turned implants with respect to implant survival, marginal bone level and peri-implant soft tissue conditions after at least 5 years in function. Clin Implant Dent Relat Res. 2014;16:230–7. Rocci A, Rocci M, Rocci C, Scoccia A, Gargari M, Martignoni M, Gottlow J, Sennerby L. Immediate loading of Brånemark system TiU...

References : Mucositis, peri-implantitis, and surv...

Esposito M, Ardebili Y, Worthington HV. Interventions for replacing missing teeth: different types of dental implants. Cochrane Database Sys Rev. 2014;7:CD003815. Salata LA, Burgos PM, Rasmusson L, Novaes AB, Papalexiou V, Dahlin C, Sennerby L. Osseointegration of oxidized and turned implants in circumferential bone defects with and without adjunctive therapies: an experimental study on BMP-2 and...

Conclusions : Mucositis, peri-implantitis, and sur...

The results of the present case series study should be interpreted in a critical light because of the small study population. However, it can be concluded that periodontally diseased subjects treated in a supportive periodontal therapy can be successfully rehabilitated with oxide-coated dental implants for a follow-up period of 3 to 6 years. The results suggest that implants in the maxilla and in...

Discussion : Mucositis, peri-implantitis, and surv...

These results from long-term clinical studies indicate that oxide-coated implants achieve equivalent survival rates and prevalence of mucositis and peri-implantitis when compared to implants with other surface characteristics. They support the assumption that the implant surface has little influence on the development of mucositis or peri-implantitis. This was subsequently confirmed in a Cochrane ...

Discussion : Mucositis, peri-implantitis, and surv...

The present study examines the success rates of oxide-coated implants in subjects with treated periodontal disease. Several long-term clinical studies on periodontally healthy subjects have revealed survival rates of 97.1 to 99.2% for oxide-coated implants [10, 24, 25]. The results of the present study show a comparable implant survival rate (96.2% in GAP and 97.1% in GCP subjects) for subjects wi...

Discussion : Mucositis, peri-implantitis, and surv...

The present study examines the success rates of oxide-coated implants in subjects with treated periodontal disease. Several long-term clinical studies on periodontally healthy subjects have revealed survival rates of 97.1 to 99.2% for oxide-coated implants [10, 24, 25]. The results of the present study show a comparable implant survival rate (96.2% in GAP and 97.1% in GCP subjects) for subjects wi...

Results : Mucositis, peri-implantitis, and surviva...

The univariate analyses showed a significantly higher risk for peri-implantitis in GAP subjects (OR = 3.294 with p = 0.027) and at implants with bone quality grade 3 (OR = 21.200 with p = 0.000). However, these differences were not significant in multivariate analyses. Both the uni- and multivariate patient-related analyses were non-significant. The implant success rate was 77.9% for GCP...

Results : Mucositis, peri-implantitis, and surviva...

All 29 subjects were examined over the period of 3 to 6 years (Table 2). For the duration of the observation period, all the remaining teeth were periodontally healthy, with PDs ≤ 3 mm and negative BOP. All subjects were non-smokers, had excellent oral hygiene, attended the follow-up examinations on a regular basis, and had no systemic disease. In total, four implants (3.1%) were lost du...

Materials and methods : Mucositis, peri-implantiti...

Peri-implant mucositis was defined as PDs ≥ 5 mm with BOP and no bone loss after the first year of loading. Peri-implantitis was defined as PDs > 5 mm with or without BOP and an annual bone loss of > 0.2 mm after the first year of loading. All technical and surgical complications (e.g., fracture of the abutment screw or superstructure, compromised wound healing) were recorded. T...

Materials and methods : Mucositis, peri-implantiti...

All patients received a supportive periodontal therapy at the Dental School of Medicine, Philipps-University, Marburg, in the course of the observation period. The first clinical examination was 2 to 4 weeks before the non-retainable teeth were extracted. The periodontally healthy residual dentition and the implants were evaluated immediately after the superstructure was inserted. Subsequently, t...

Materials and methods : Mucositis, peri-implantiti...

Second-stage surgery was performed in the maxilla after 6 months and in the mandible after 3 months. Implant placement and second-stage surgery were performed by a single periodontist (R.M.). About 4 weeks after the final abutments were placed, GCP subjects were rehabilitated with single crowns, implant-supported bridges, or removable superstructures, according to the Marburg double crown syst...

Materials and methods : Mucositis, peri-implantiti...

A total of 29 partially edentulous subjects were consecutively recruited from the Dental School of Medicine, Philipps-University, Marburg, Germany between April 2010 and April 2013 (Table 1). Subjects were excluded for the following reasons: history of systemic disease (e.g., cardiovascular diseases, diabetes mellitus, osteoporosis), pregnancy, untreated caries, current orthodontic treatment, con...

Background : Mucositis, peri-implantitis, and surv...

The aim of this long-term clinical study on partially edentulous subjects treated for periodontal disease was to evaluate the prevalence of mucositis and peri-implantitis and to determine the survival and success rates of dental implants with oxide-coated surfaces.

Background : Mucositis, peri-implantitis, and surv...

In recent years, a great number of different implant systems varying in materials, surface structure, and macroscopic design have been introduced to the dental market [1]. In studies using implants with modified surfaces, it was concluded that rough surfaces induce a stronger initial bone response, achieve stability more rapidly, and integrate more fully with extant bone [2,3,4,5,6]. Dental implan...

Abstract : Mucositis, peri-implantitis, and surviv...

The aim of this case-series study is to evaluate the prevalence of mucositis, peri-implantitis, and survival and success rates of oxide-coated implants in subjects treated for periodontitis. Twenty-four subjects treated for generalized chronic periodontitis (GCP) and five treated for generalized aggressive periodontitis (GAP) were orally rehabilitated with a total of 130 dental implants. Subjects...

Fig. 8. There were moderately significant and posi...

Fig. 8. There were moderately significant and positive correlations between the ALP levels and OC levels at all measurements from week 1 to week 12. The OC levels in pg/μg protein were associated with the ALP levels in nM/μg protein at the implant site (a), control site (b), and pooled samples of the control and implant sites (c) Fig. 8. There were moderately significant and positive correl...

Fig. 7. Comparison between the trend of the biomar...

Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time Fig. 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time

Fig. 6. There were weakly significant and positive...

Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all measurements from week 1 to week 12. At the implant site, the ALP levels in nM/μg protein (a) or the OC levels in pg/μg protein (b) were associated with ISQ values Fig. 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all...

Fig. 5. Change in the median values of the OC leve...

Fig. 5. Change in the median values of the OC level over time. In the test group, the OC level continuously increased with time. There was a statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Fig. 4. Change in the median values of the ALP lev...

Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level decreased at 1–4 weeks and then increased at 6, 8, 10, and 12 weeks. There was no statistically significant difference in the ALP level in either the control or the test groups at any measurement Fig. 4. Change in the median values of the ALP level over time. In the test group, the ALP level d...

Fig. 3. Change in the median values of the GCF (co...

Fig. 3. Change in the median values of the GCF (control group) and PICF (test group) volume over time. In the test group, the PICF volume continuously decreased with time (a). There were no significant differences in the median values of the crevicular fluid volume in either the control group or the test groups at any measurement (b) Fig. 3. Change in the median values of the GCF (control gro...

Fig. 2. Change in the mean ISQ values over time. T...

Fig. 2. Change in the mean ISQ values over time. There was a statistically significant decrease in the mean ISQ values between 1 and 3 weeks (P 

Fig. 1. Timeline of the clinical study. I—implan...

Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth Fig. 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth

Table 5 Crevicular fluid ALP and OC levels : Relat...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks...

Table 4 Crevicular fluid volume : Relation between...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks...

Table 3 ISQ values according to gender and bone qu...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks...

Table 2 Profile of patients : Relation between the...

Patient no. Age Sex Positiona Bone qualityb 1 34 ...

Table 1 Inclusion and exclusion criteria : Relatio...

Inclusion criteria Exclusion criteria Patients aged 25–65 years Presence of periodontal disease or periapical lesions Ability to participat...

About this article : Relation between the stabilit...

Tirachaimongkol, C., Pothacharoen, P., Reichart, P.A. et al. Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study. Int J Implant Dent 2, 27 (2016). https://doi.org/10.1186/s40729-016-0058-y Download citation Received: 14 September 2016 Accepted: 18 November 2016 Published: 08 December 2016 DOI...

Rights and permissions : Relation between the stab...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Relation between the stabilit...

Center of Excellence for Dental Implantology, Faculty of Dentistry, Chiang Mai University, Suthep sub-district, A. Muang, Chiang Mai, 50200, Thailand Choknapa Tirachaimongkol & Pathawee Khongkhunthian Department of Biochemistry, Faculty of Medicine, Thailand Excellence Center for Tissue Engineering and Stem Cells, Chiang Mai, Thailand Peraphan Pothacharoen Department of Oral Medicine, Dental...

Acknowledgements : Relation between the stability ...

The authors acknowledge Mrs. Yupaporn Kiatsakulcharoen and Miss Kamolwan Mangkalad, the Center of Excellent for Dental Implantology, Chiang Mai University for clinical assistance, Mr. Aitthiphon Chongchai, the Department of Biochemistry, Faculty of Medicine Chiang Mai University for laboratory assistance, Dr.Thanapat Sastraruji, Faculty of Dentistry, Chiang Mai University for statistical consultat...

References : Relation between the stability of den...

Lekholm U, Zarb G, Albrektsson T. Tissue integrated prostheses. Patient selection and preparation. Chicago: Quintessence Publishing Co Inc; 1985. p. 199–209. Download references

References : Relation between the stability of den...

Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 2003;3:251–62. Emecen-Huja P, Eubank TD, Shapiro V, Yildiz V, Tatakis DN, Leblebicioglu B. Peri-implant versus periodontal wound healing. J Clin Periodontol. 2013;40:816–24. Chapple LLC, Socransky SS, Dibart S, Glenwright DH, Matthews JB. Chemiluminescent as...

References : Relation between the stability of den...

Bischof M, Nedir R, Szmukler-Moncler S, Bernard JP, Samson J. Implant stability measurement of delayed and immediately loaded implants during healing. Clin Oral Implants Res. 2004;5:529–39. Sim CPC, Lang NP. Factors influencing resonance frequency analysis assessed by Osstell mentor during implant tissue integration: I. Instrument positioning, bone structure, implant length. Clin Oral Implants ...

References : Relation between the stability of den...

Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155–70. Khongkhunthian P. Implant features. In: Khongkhunthian P, editor. PW Plus Thai Dental Implant. Bangkok: STZ Mospace design; 2015. p. 12. Lacey DL, Timms E, Tan HL, Kelley MJ, Dunstan CR, ...

Conclusions : Relation between the stability of de...

Within the limitations of this study and cautious interpretation due to small number of implants/patients, the ISQ values were weakly correlated with both ALP and OC molecules in PICF during the healing period. The results also show that osteocalcin may be used as a biological marker for monitoring implant healing at 6, 8, 10, and 12 weeks after implant placement. The ISQ values showed high stabi...

Discussion : Relation between the stability of den...

Vogel and Marcotte [33] suggested that the correlation between mRNA and protein quantities is approximately 40%. As there are many mechanisms between transcription and translation, especially in human cell and protein stability, at the gene expression level, the transcription data is beneficial in making decisions about molecular candidates for future studies at the protein level. The colorimetric...

Discussion : Relation between the stability of den...

The main sources of ALP in GCF are neutrophils, bacteria within dental plaque, fibroblasts, and osteoblasts [28]. Plagnat et al. [29] suggested that longitudinal monitoring of ALP in PICF might confirm its possible use as a marker of implant failure. Considering the change in the median values of the ALP level over time, in the test group, the ALP level decreased at 1–4 weeks and then increased...

Discussion : Relation between the stability of den...

The results of this study show that, at the time of implantation, the ISQ values ranged between 67.5 and 83. The mean initial ISQ value was 77.0 ± 1.32. These findings are in harmony with those of previous studies [16, 18]. Tallarico et al. (2011) reported that the macro-design of dental implant affects the primary anchorage [16]. They suggested that the high initial ISQ value is a factor in ...

Results : Relation between the stability of dental...

At the implant site, the OC level continuously increased with time. According to the Friedman followed by Wilcoxon signed-rank tests, there was statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Results : Relation between the stability of dental...

Ten patients, seven females, and three males, aged 42.4 ± 11.99 years (range, 28 to 64 years), with either a first mandibular or second mandibular molar edentulous area, who required a single nonsubmerged implant participated in this study, as shown in Table 2. The implants used for all patients were 10 mm long and 5 mm in diameter. All patients completed the follow-up. None of the impla...

Methods : Relation between the stability of dental...

Data were analyzed by using SPSS 17.0 software (SPSS Inc., Chicago, IL, USA). Repeated measures analysis of variance was performed to evaluate the change in the ISQ values at each measurement. The independent samples t test was used to investigate the differences in implant stability in the patients’ gender and bone quality. The Friedman test, followed by the Wilcoxon signed-rank test, was used ...

Methods : Relation between the stability of dental...

The level of OC was measured by using commercially available ELISA kits (Human Osteocalcin Quantikine ELISA Kit, R&D Systems, Inc., Minneapolis, MN, USA) according to the manufacturer’s instructions. A 100 μl volume of Assay Diluent RD1-117 (R&D Systems) was added into each well of the microplate and then 50 μl of standard (0–64 ng/ml) or sample was added to each well. The microplate was ...

Methods : Relation between the stability of dental...

To observe the level of two bone formation biomarkers (alkaline phosphatase and osteocalcin) during the osseointegration period compared with control group using GCF from the first molar of the contralateral side of implant position, the sample collection of GCF was performed before the surgical procedure, immediately after the surgical operation and after 1, 2, 3, 4, 6, 8, 10, and 12 weeks. The ...

Methods : Relation between the stability of dental...

The study is a prospective clinical study during the 3-month healing period of implant. The study was approved by the Human Experimentation Committee, Faculty of Dentistry, Chiang Mai University. The study outline is shown in Fig. 1. Ten patients, who were partially edentulous in the mandibular posterior region for whom a single nonsubmerged implant was planned, participated in this study. All o...

Background : Relation between the stability of den...

Osteocalcin (OC) is the most plentiful noncollagenous protein of the bone matrix. It is secreted from odontoblasts, osteocytes, and osteoblasts, in order to bind hydroxyapatite and calcium during matrix mineralization [7]. It is one of the serological markers in the bone formation process. Numerous studies have shown increased OC levels in bone formation. However, increased OC level relates more t...

Background : Relation between the stability of den...

Dental implants have shown a high success rate for rehabilitation of edentulous patients if certain conditions are met during treatment. Nevertheless, the risk of failure remains difficult to predict. The achievement of osseointegration depends on many factors, such as a suitable host, biocompatible materials, careful surgery, and an appropriate healing time [1].The primary stability comes from th...

Background : Relation between the stability of den...

Dental implants have shown a high success rate for rehabilitation of edentulous patients if certain conditions are met during treatment. Nevertheless, the risk of failure remains difficult to predict. The achievement of osseointegration depends on many factors, such as a suitable host, biocompatible materials, careful surgery, and an appropriate healing time [1]. The primary stability comes from ...

Abstract : Relation between the stability of denta...

The purposes of this study were to examine the correlation between the stability of dental implants and bone formation markers during the healing period and to monitor the stability of dental implants using the resonance frequency analysis (RFA) method. The null hypothesis of the study is no correlation between the stability of dental implant and bone formation markers. The study is a prospective...

Fig. 2. Figure illustrating the proposed mucosal t...

Fig. 2. Figure illustrating the proposed mucosal thickening index. A ≤1 mm, indicating no thickening; B >1 mm but ≤2 mm, indicating minimal thickening; C >2 mm but ≤5 mm, indicating moderate thickening; D >5 mm, indicating severe thickening Fig. 2. Figure illustrating the proposed mucosal thickening index. A ≤1 mm, indicating no thickening; B >1 mm but ≤2 mm, indicating min...

Fig. 1. Figure illustrating the reference points o...

Fig. 1. Figure illustrating the reference points of the CBCT measurements. A: most posterior point of the sinus wall; B: most anterior point of the sinus wall; C: mid-point between A and B; C1: measurement of mucosal thickening perpendicular to A–B line at point C; D: mid-point between A and C; D1: measurement of mucosal thickening perpendicular to A–B line at point D; E: mid-point between B...

Table 2 Statistical results after inter-variable a...

  Gender Respiratory diseases Cardio-vascular diseases Diabetes mellitus Smoking Hist...

Table 1 CBCT measurements of sinus mucosal thicken...

Patient Anterior (E1-floor of the sinus) Middle (C1-floor of the sinus) Posterior (D1-floor of the sinus) ...

About this article : Dental implants and grafting ...

Maska, B., Lin, GH., Othman, A. et al. Dental implants and grafting success remain high despite large variations in maxillary sinus mucosal thickening. Int J Implant Dent 3, 1 (2017). https://doi.org/10.1186/s40729-017-0064-8 Download citation Received: 18 October 2016 Accepted: 13 January 2017 Published: 18 January 2017 DOI: https://doi.org/10.1186/s40729-017-0064-8

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Dental implants and grafting ...

You can also search for this author in PubMed Google Scholar Correspondence to Yvonne Kapila.

Author information : Dental implants and grafting ...

Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, 1011 N University Ave, Ann Arbor, MI, USA Bartosz Maska, Guo-Hao Lin, Abdullah Othman, Shabnam Behdin, Suncica Travan, Erika Benavides & Yvonne Kapila Department of Surgical Sciences, School of Dentistry, Marquette University, 1801 W Wisconsin Ave, Milwaukee, WI, USA Guo-Hao Lin Department of Peri...

Acknowledgements : Dental implants and grafting su...

The authors thank Ms. Victoria Zakrzewski for her help with the figure generation and preparation. Co-primary author BM contributed to the CBCT measurement and preparation of the manuscript. Co-primary author G-HL contributed to the data analysis and preparation of the manuscript. Second author AO contributed to the protocol preparation, case review, case selection, and preparation of the manuscr...

References : Dental implants and grafting success ...

Romanos GE, Froum S, Costa-Martins S, Meitner S, Tarnow DP. Implant periapical lesions: etiology and treatment options. J Oral Implantol. 2011;37:53–63. Acharya A, Hao J, Mattheos N, Chau A, Shirke P, Lang NP. Residual ridge dimensions at edentulous maxillary first molar sites and periodontal bone loss among two ethnic cohorts seeking tooth replacement. Clin Oral Implants Res. 2014;25:1386–94...

References : Dental implants and grafting success ...

Pazera P, Bornstein MM, Pazera A, Sendi P, Katsaros C. Incidental maxillary sinus findings in orthodontic patients: a radiographic analysis using cone-beam computed tomography (CBCT). Orthod Craniofac Res. 2011;14:17–24. Ritter L, Lutz J, Neugebauer J, et al. Prevalence of pathologic findings in the maxillary sinus in cone-beam computerized tomography. Oral Surg Oral Med Oral Pathol Oral Radiol...

References : Dental implants and grafting success ...

Gardner DG. Pseudocysts and retention cysts of the maxillary sinus. Oral Surg Oral Med Oral Pathol. 1984;58:561–7. Chiapasco M, Palombo D. Sinus grafting and simultaneous removal of large antral pseudocysts of the maxillary sinus with a micro-invasive intraoral access. Int J Oral Maxillofac Surg. 2015;44:1499–505. Cano J, Campo J, Alobera MA, Baca R. Surgical ciliated cyst of the maxilla. Cl...

References : Dental implants and grafting success ...

Beretta M, Poli PP, Grossi GB, Pieroni S, Maiorana C. Long-term survival rate of implants placed in conjunction with 246 sinus floor elevation procedures: results of a 15-year retrospective study. J Dent. 2015;43:78–86. Del Fabbro M, Corbella S, Weinstein T, Ceresoli V, Taschieri S. Implant survival rates after osteotome-mediated maxillary sinus augmentation: a systematic review. Clin Implant D...

Abbreviations : Dental implants and grafting succe...

Cone-beam computed tomographic Protected Health Information Sinus floor elevation

Conclusions : Dental implants and grafting success...

Our study found that the largest tissue thickening was present in the middle section of the maxillary sinus. This tissue thickening did not vary based on gender, age, or smoking status, nor did it relate to the underlying alveolar ridge height. However, patients with a history of periodontal diseases demonstrated a significant association with mucosal thickening. A mucosal thickening index was pro...

Discussion : Dental implants and grafting success ...

Although residual alveolar ridge height has been associated with sinus mucosal thickening [36], our study did not find a significant association between these two parameters. Acharya et al. [36] reported that lower available bone height in the subsinus region was related to thickened sinus membranes within an Asian-Indian and Hong Kong-based Chinese population. Differences in the ethnic compositio...

Discussion : Dental implants and grafting success ...

Based on the findings of the current study, a history of periodontal disease is the only identified parameter significantly associated with sinus mucosal thickening. This finding indicates that clinicians should expect some degree of mucosal thickening when performing sinus augmentation procedures in a previously periodontally involved site. This finding is consistent with several previously publi...

Discussion : Dental implants and grafting success ...

CBCT imaging has been recognized as a more sensitive imaging modality for identifying sinus thickening and pathoses in the posterior maxilla compared to panoramic radiography [21, 22]. This could explain why the current study identified a higher prevalence of mucosal thickening compared to earlier studies [23]. However, compared to other similar CBCT studies [21, 24, 25], the prevalence reported i...

Results : Dental implants and grafting success rem...

Twenty-nine CBCT images (11 females and 18 males) were included in this study. All the implants placed in these included cases survived, representing a 100% implant survival rate. With regards to measurements of mucosal thickening, the intra-examiner reproducibility revealed an exact intra-examiner correlation of 99%, with a p value of 0.40 for a t test for independent samples, indicating a high r...

Methods : Dental implants and grafting success rem...

The sites that were measured are specified in the image below (Fig. 1). The most posterior and anterior aspects of the visible maxillary sinus were measured. The ½ point along with the ¼ and ¾ points were then selected, and the measurements of the mucosal thickening were then completed at these three sites. The thickest portion of the mucosa was also measured if it did not coincide with one of...

Methods : Dental implants and grafting success rem...

The study required access to University of Michigan Protected Health Information (PHI). PHI was necessary in order to track and coordinate the CBCT data and dental and medical history for each subject. Corresponding subject charts and electronic records were reviewed for retrieval of relevant implant placement and restorative history, medical history, and demographic information, including gender ...

Methods : Dental implants and grafting success rem...

Our study hypothesis was that mucosal thickening of more than 2 mm and up to 1/3 of the volume of the sinus would not alter the predictability for SFE and dental implant placement. The primary outcome was to determine the success rate of dental implant placement in augmented maxillary sinus areas with mucosal thickening. A secondary outcome was to evaluate the effect of gender, age, and smoking o...

Background : Dental implants and grafting success ...

Despite the high survival rate of dental implants inserted in maxillary sinuses that have undergone sinus floor elevation (SFE) with bone grafting, complications still occur [1–3]. Sinus membrane perforation is reported to be the most common complication [4, 5]. Postoperative maxillary sinusitis is less common (0–22%) [6, 7]; nevertheless, it could potentially compromise the outcome of SFE and...

Abstract : Dental implants and grafting success re...

Although mucosal thickening is the most common radiographic finding observed regarding sinus pathology, the knowledge regarding its clinical significance on the outcomes of dental implants and grafting in the maxillary sinuses is still limited. We hypothesized that mucosal thickening would not alter the predictability for sinus floor augmentation and dental implant placement. The purpose of this r...

About this article : Maxillary segmental osteoperi...

Tsegga, T., Wright, T. Maxillary segmental osteoperiosteal flap with simultaneous placement of dental implants: case report of a novel technique. Int J Implant Dent 3, 2 (2017). https://doi.org/10.1186/s40729-017-0067-5 Download citation Received: 06 December 2016 Accepted: 13 January 2017 Published: 19 January 2017 DOI: https://doi.org/10.1186/s40729-017-0067-5

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Author information : Maxillary segmental osteoperi...

Department of Oral & Maxillofacial Surgery, San Antonio Military Medical Center, 3551 Roger Brooke Dr., Ft. Sam Houston, 78234, TX, USA Tibebu Tsegga & Thomas Wright Department of Oral & Maxilofacial Surgery, Wilford Hall Ambulatory Surgical Center, 2200 Bergquist Dr, Suite 1, Lackland AFB, TX, 78236, USA Tibebu Tsegga & Thomas Wright You can also search for this author in ...

References : Maxillary segmental osteoperiosteal f...

Irinakis T. Efficacy of injectable demineralized bone matrix as graft material during sinus elevation surgery with simultaneous implant placement in the posterior maxilla: clinical evaluation of 49 sinuses. J Oral and Maxillofac Surg. 2011;69:134–41. Chiapasoo M, Casentini P, Zaniboni M. Bone augmentation procedures in implant dentistry. Int J Oral Maxillofac Implants. 2009;24:237–69. Jenson...

Conclusions : Maxillary segmental osteoperiosteal ...

This case highlights the evolving variations in dentoalveolar augmentation with an emphasis on concomitant implant placement. In the most traditional sense, a vertical osteoperiosteal flap technique would be bound with a stable basal bone that can be used to anchor simultaneous dental implant placement. Further refinement should consider minimizing crestal reflection and overall labial bone resorp...

Discussion : Maxillary segmental osteoperiosteal f...

A critical appraisal of the gingival architecture in the final end point of this case demonstrates some radiolucency through the soft tissue outlining the platform of the Nobel Biocare TiUnite implant. This would lead us to believe that either the transmucosal bone level placement attempt was inaccurate or excessive reflection of the labial tissue has caused some degree of resorption. This is anot...

Discussion : Maxillary segmental osteoperiosteal f...

A suitable alternative surgical management of this particular case might have been to simply perform an alveoloplasty to produce the desired inter-occlusal clearance and proceed with placement of implant and simultaneous direct sinus lift. That would have left more of the apical portion of the implant within the grafted sinus and possibly modified the location of keratinized band of tissue. The lo...

Case Presentation : Maxillary segmental osteoperio...

A 35-year-old female with a 10-year history of partial acquired edentulism at site numbers 3 and 4 presented to our clinic for dental implant evaluation. Preoperative clinical examination revealed a reproducible intercuspation, well-delineated band of keratinized tissue, and decreased inter-occlusal clearance to allow for optimal dimension of prosthetic crowns (Fig. 1). Radiographs demonstrated e...

Background : Maxillary segmental osteoperiosteal f...

Obtaining proper occlusal clearance to allow for a single unit crown restoration is a fundamental prerequisite for dental implant restoration. Long-standing edentulous sites are often fraught with disuse atrophy and unopposed supra-eruption of the opposing dentition. In the posterior maxillae/mandible, there are vital structures that have to be mobilized in order to allow space for either bone tra...

Abstract : Maxillary segmental osteoperiosteal fla...

Dental restorative space from the opposing dentition requires adequate distance for restorative material for an acceptable restoration. Typically, long-standing edentulous alveolar ridges will have vertical and or horizontal defects that require alveolar ridge augmentation for ideal dental implant restorations. Along with these defects, one will see the opposing dentition supra erupt which can obl...

About this article : Case report on managing incom...

Boehm, T.K. Case report on managing incomplete bone formation after bilateral sinus augmentation using a palatal approach and a dilating balloon technique. Int J Implant Dent 3, 3 (2017). https://doi.org/10.1186/s40729-017-0065-7 Download citation Received: 08 November 2016 Accepted: 13 January 2017 Published: 19 January 2017 DOI: https://doi.org/10.1186/s40729-017-0065-7...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Case report on managing incom...

Western University of Health Sciences College of Dental Medicine, 309 E Second Street, Pomona, CA, 91766, USA Tobias K. Boehm You can also search for this author in PubMed Google Scholar Correspondence to Tobias K. Boehm.

Acknowledgements : Case report on managing incompl...

I would like to thank the former dental students Dr. Lily Hoang and Dr. Shirley Hsieh and their prosthodontic supervisors Dr. James Ywom, Dr. Steven Sanders, and Dr. Alessandro Urdaneta for providing this patient’s continued restorative and preventive care after the surgeries and the dental assistants of the Western University of Health Sciences Dental Center, Mrs. Cindy Morton and Mrs. Melody P...

References : Case report on managing incomplete bo...

Penarrocha-Diago M, Galan-Gil S, Carrillo-Garcia C, Penarrocha-Diago D, Penarrocha-Diago M. Transcrestal sinus lift and implant placement using the sinus balloon technique. Med Oral Patol Oral Cir Bucal. 2012;17(1):e122–8. Kfir E, Goldstein M, Abramovitz I, Kfir V, Mazor Z, Kaluski E. The effects of sinus membrane pathology on bone augmentation and procedural outcome using minimal invasive antr...

References : Case report on managing incomplete bo...

Hernandez-Alfaro F, Torradeflot MM, Marti C. Prevalence and management of Schneiderian membrane perforations during sinus-lift procedures. Clin Oral Implants Res. 2008;19(1):91–8. Wallace SS, Mazor Z, Froum SJ, Cho SC, Tarnow DP. Schneiderian membrane perforation rate during sinus elevation using piezosurgery: clinical results of 100 consecutive cases. Int J Periodontics Restorative Dent. 2007;...

Conclusions : Case report on managing incomplete b...

We conclude that incomplete bone formation after sinus augmentation can be managed successfully through a variety of re-entry procedures and that successful long-term implant placement and restoration is possible in a compliant patient of good overall health.

Case presentation : Case report on managing incomp...

Healing was uneventful with little discomfort reported by the patient during the first week, and implant uncovery revealed an implant firmly embedded in bone after 12 months. A third implant was placed at the no. 30 site and supraerupted no. 18 extracted as planned. Restoration of the implants was uneventfully performed by senior dental students supervised by various prosthodontists (Fig. 11). P...

Case presentation : Case report on managing incomp...

For the left side, we decided to access the sinus using a lateral window as the area of deficient bone was much larger in size and more complex in shape. We also decided to approach this area from the palate, as the defect was closer to the palate and required much less bone removal as a buccal approach. Most importantly, we were already familiar with the anatomical structures on the lower medial ...

Case presentation : Case report on managing incomp...

A year later, we requested cone beam computed tomography for both posterior maxilla sites, and we found incomplete bone growth in the sinus. On the right side, bone growth had occurred only distal to the desired implant site, and there was an ovoid extension of sinus into the area planned for implant placement (Fig. 4). On the left side, a finger-like extension of sinus had developed between graf...

Case presentation : Case report on managing incomp...

Lateral window sinus augmentation was performed on each side during appointments spaced 3 months apart, following the technique developed by Tatum in 1974. For each site, a midcrestal mucoperiosteal incision with buccal releases was created, and the lateral Schneiderian membrane of the maxillary sinus exposed through an ovoid window osteotomy of about 15 mm diameter. Osteotomy was performed usin...

Case presentation : Case report on managing incomp...

A 65-year-old retired Caucasian male presented to the Western University of Health Sciences Dental Center expressing an interest in implants after consulting with a private practice periodontist and a dentist from a large implant dentistry practice. He had no medical conditions or known allergies, but reported a 40-pack-year history of using tobacco and quit just before attending the Dental Center...

Background : Case report on managing incomplete bo...

Membrane tears are a significant concern as they may result in postoperative complications such as an oroantral communication as reported recently. In this case, the communication was managed by inserting a fibrin sponge, but it resulted in a cyst-like concavity within grafted bone, which was subsequently managed by re-entry and grafting of the affected site prior to implant placement [14]. As see...

Background : Case report on managing incomplete bo...

Patients with severe periodontal disease often display severely resorbed ridges in the posterior maxilla. Implant therapy can be a challenge for those patients as available bone height is limited by the maxillary sinus. Although sinus augmentation using subantral or lateral window approaches are routinely used, complications occur that may limit bone augmentation in the sinus after any given proce...

Abstract : Case report on managing incomplete bone...

Patients with resorbed edentulous alveolar ridges in the posterior maxilla often require lateral window sinus augmentation procedures prior to implant placement. Lateral window sinus augmentation procedures can produce incomplete bone augmentation as consequence of surgical and healing complications producing unusual and complex sinus anatomy. Although incomplete bone formation after sinus augment...

About this article : Customized SmartPeg for measu...

Dhaliwal, J.S., Albuquerque, R.F., Fakhry, A. et al. Customized SmartPeg for measurement of resonance frequency of mini dental implants. Int J Implant Dent 3, 4 (2017). https://doi.org/10.1186/s40729-017-0066-6 Download citation Received: 09 November 2016 Accepted: 13 January 2017 Published: 01 February 2017 DOI: https://doi.org/10.1186/s40729-017-0066-6

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Customized SmartPeg for measu...

Faculty of Dentistry, McGill University, 2001 McGill College Avenue, Suite 500, Montreal, Quebec, H3A 1G1, Canada Jagjit Singh Dhaliwal, Ali Fakhry & Jocelyne S. Feine Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil Rubens F. Albuquerque Jr Department of Zoology, Panjab University, Chandigarh, India Sukhbir Kaur PAPRSB Institute of Health Sci...

References : Customized SmartPeg for measurement o...

Dhaliwal J, Albuquerque R, Murshed, M, Tamimi, F, Feine, JS. A histomorphometric comparison of osseointegration with MDIs and standard implants. IADR/AADR/CADR 91st General Session, Seattle, Washington, USA, March 20–23, 2013 Zix J, Hug S, Kessler-Liechti G, Mericske-Stern R. Measurement of dental implant stability by resonance frequency analysis and damping capacity assessment: comparison of b...

References : Customized SmartPeg for measurement o...

Barros RR, Novaes Jr AB, Muglia VA, Iezzi G, Piattelli A. Influence of interimplant distances and placement depth on peri-implant bone remodeling of adjacent and immediately loaded Morse cone connection implants: a histomorphometric study in dogs. Clin Oral Implants Res. 2010;21(4):371–8. Epub 2010/02/05. Marin C, Bonfante EA, Granato R, Suzuki M, Granjeiro JM, Coelho PG. The effect of alterati...

References : Customized SmartPeg for measurement o...

Meredith N, Book K, Friberg B, Jemt T, Sennerby L. Resonance frequency measurements of implant stability in vivo. A cross-sectional and longitudinal study of resonance frequency measurements on implants in the edentulous and partially dentate maxilla. Clin Oral Implants Res. 1997;8(3):226–33. Epub 1997/06/01. Meredith N, Alleyne D, Cawley P. Quantitative determination of the stability of the im...

References : Customized SmartPeg for measurement o...

Ersanli S, Karabuda C, Beck F, Leblebicioglu B. Resonance frequency analysis of one-stage dental implant stability during the osseointegration period. J Periodontol. 2005;76(7):1066–71. Epub 2005/07/16. Bornstein MM, Chappuis V, von Arx T, Buser D. Performance of dental implants after staged sinus floor elevation procedures: 5-year results of a prospective study in partially edentulous patients...

References : Customized SmartPeg for measurement o...

Shatkin TE, Oppenheimer BD, Oppenheimer AJ. Mini dental implants for long-term fixed and removable prosthetics: a retrospective analysis of 2514 implants placed over a five-year period. Compend Contin Educ Dent. 2007;28(2):92–9. quiz 100-1. Epub 2007/02/27. Griffitts TM, Collins CP, Collins PC. Mini dental implants: an adjunct for retention, stability, and comfort for the edentulous patient. Or...

References : Customized SmartPeg for measurement o...

Branemark PI, Adell R, Breine U, Hansson BO, Lindstrom J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3(2):81–100. Epub 1969/01/01. Meredith N. Assessment of implant stability as a prognostic determinant. Int J Prosthodont. 1998;11(5):491–501. Epub 1999/01/29. Lioubavina-Hack N, Lang NP, Karring T. Significance of primar...

Conclusions : Customized SmartPeg for measurement ...

The results of this animal study indicate that ISQ measurement of these single-piece MDIs is possible with the help of a custom-made SmartPeg and that 3M™ESPE™MDIs attain primary and secondary stability at the same levels as standard implants in the rabbit tibia.

Discussion : Customized SmartPeg for measurement o...

As there are no studies that provide data based on resonance frequency measurements for single-piece MDIs, the exact RFA threshold values for MDIs may have to be identified with more studies conducted in vivo. The resonance frequency assessment with a customized SmartPeg would be a useful tool to provide clinically useful information about the condition of the bone-implant interface of 3M™ ESPE...

Discussion : Customized SmartPeg for measurement o...

If the initial ISQ value is high, a small drop in stability normally levels out with time. A big drop in stability or decrease should be taken as a warning sign. Lower values are expected to be higher after the healing period. The opposite could be a sign of an unsuccessful implant, and actions should be taken accordingly. Studies have shown that the resonance frequency value is greatly associate...

Discussion : Customized SmartPeg for measurement o...

It is important to measure the Implant Stability Quotient (ISQ) of single-piece mini dental implants as they are becoming increasingly popular, with the concomitant increase in publications demonstrating their high survival and success rates. Although the clinical use of Osstell devices is also increasing, there is lack of studies on its use with single-piece implants, which do not have internal t...

Results : Customized SmartPeg for measurement of r...

The ISQ values obtained while calibrating the customized SmartPeg were similar to in vivo results. Median ISQ values at insertion and at 6 postoperative weeks were 53.3 (IQR 8.3) and 60.5 (5.5) for the 3M™ESPE™MDIs, and 58.5 (4.75) and 65.5 (9.3) for the Ankylos® implants, respectively, with no statistical difference (Figs. 2 and 3). The ISQ values of both 3M™ESPE™ MDI and Ankylos® (Fig...

Methods : Customized SmartPeg for measurement of r...

ISQ values were averaged and compared between implant types and times using Wilcoxon’s matched pairs signed-rank tests at a significance level of p 

Methods : Customized SmartPeg for measurement of r...

For the MDIs, a small longitudinal skin incision was made just distal to the tibia/femur joint. The tibia/femur head was exposed subperiosteally, and an osteotomy was performed with the pilot drill under copious irrigation with saline solution, transposing the cortical bone to the depth of 0.5 mm. The implants were aseptically transferred to the bone site and manually rotated clockwise while exer...

Methods : Customized SmartPeg for measurement of r...

Single use Osstell SmartPegs for standard implants are made from a soft metal with a zinc-coated magnet mounted on top of it and attached to the implants or abutments’ internal threads. As the company does not provide SmartPegs for one-piece implants, we developed a customized SmartPeg for mini dental implants (3M™ESPE™ MDIs), which do not have internal threads (Fig. 1). After confirming th...

Objective : Customized SmartPeg for measurement of...

The aim of the study is to test the feasibility of a customized SmartPeg for ISQ measurement of single-piece mini dental implants and to compare the primary stability of a standard and the mini dental implant (3M™ESPE™MDI) in a rabbit model after 6 weeks of healing.

Background : Customized SmartPeg for measurement o...

There are no published studies on the ISQ measurement of mini dental implants, as SmartPegs for these implants are not available till date. Since these are one-piece implants and do not have an internal thread for the SmartPeg’s attachment, a custom-made SmartPeg needs to be fabricated for ISQ measurement. Therefore, we developed and tested a customized SmartPeg for 3M™ESPE™ MDIs to measure ...

Background : Customized SmartPeg for measurement o...

Mechanical testing methods like reverse torque, or “pullout test,” have been used to study and measure the mechanical interface between implant and bone in various ways [22, 23]. The Branemark group has evaluated the mechanical properties of osseointegrated implants using torsion and pullout tests and lateral loading tests [24, 25]. Presence or absence of mobility and the bone level around the...

Background : Customized SmartPeg for measurement o...

Osseointegration refers to the phenomenon for close apposition of the bone to the surface of an implant with no interposing tissue that can be clinically demonstrated by absence of mobility [1, 2]. Obtaining primary stability seems to be a precondition for a successful osseointegration [3]. Dental implants have a success rate of over 90% and are available in various sizes with different surfaces [...

Abstract : Customized SmartPeg for measurement of ...

The new custom-made SmartPeg is suitable for measuring the Implant Stability Quotient of 3M™ESPE™MDIs. The primary stability of 3M™ESPE™MDIs is similar to the primary stability attained by standard implants in the rabbit tibia.

Abstract : Customized SmartPeg for measurement of ...

One-piece narrow diameter implants (NDIs) have been recommended as “Single-tooth replacements in the anterior zones, single posterior, multiple-unit fixed dental prosthesis (FDP), edentulous jaws to be rehabilitated with FDP, and edentulous jaws rehabilitation with overdentures in situations with reduced mesiodistal space or reduced ridge width.” (ITI consensus 2013). Since NDIs can be immedia...

About this article : Zirconia implants and peek re...

Parmigiani-Izquierdo, J.M., Cabaña-Muñoz, M.E., Merino, J.J. et al. Zirconia implants and peek restorations for the replacement of upper molars. Int J Implant Dent 3, 5 (2017). https://doi.org/10.1186/s40729-016-0062-2 Download citation Received: 13 October 2016 Accepted: 22 December 2016 Published: 20 February 2017 DOI: https://doi.org/10.1186/s40729-016-0062-2

Rights and permissions : Zirconia implants and pee...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Zirconia implants and peek re...

Periodontics Unit, Faculty of Medicine and Dentistry, University of Murcia (Spain), Murcia, Spain Arturo Sánchez-Pérez Clínica CIROM, Murcia, 30001, Spain José María Parmigiani-Izquierdo, María Eugenia Cabaña-Muñoz & José Joaquín Merino Clínica Odontologíca Universitaria, Hospital Morales Meseguer, 2ª planta, C/ Marqués de los Vélez s/n, Murcia, 30008, Spain Arturo Sánchez-...

References : Zirconia implants and peek restoratio...

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References : Zirconia implants and peek restoratio...

Bormann K-H, Gellrich N-C, Kniha H, Dard M, Wieland M, Gahlert M. Biomechanical evaluation of a microstructured zirconia implant by a removal torque comparison with a standard Ti-SLA implant. Clin oral implants res. 2012;23:1210–6. Oliva J, Oliva X, Oliva JD. One-year follow-up of first consecutive 100 zirconia dental implants in humans: a comparison of 2 different rough surfaces. Int j oral ma...

References : Zirconia implants and peek restoratio...

Brånemark PI, Hansson BO, Adell R, Breine U, Lindström J, Hallén O, et al. Osseointegrated implants in the treatment of the edentulous jaw. Experience from a 10-year period. Scand j plast reconstr surg suppl. 1977;16:1–132. Parmigiani-Izquierdo JM. TécnicaAtraumática en Implantología. Rev esp odontoestomatológica implant. 11:30–5. Parmigiani-Izquierdo JM, Sánchez-Pérez A, Cabaña-Mu...

Conclusions : Zirconia implants and peek restorati...

Zirconia implants with PEEK restorations can be considered a good alternative for replacing natural teeth. Their biocompatibility and biostability make them a promising material for those patients who suffer from allergies and sensitivity to metal alloys. PEEK restorations are a valid and alternative recommendation when using zirconia implants because of their cushioning effect and elastic modulu...

Case presentation : Zirconia implants and peek res...

In addition to PEEK, new coatings based on PMMA or composite materials (Anaxblent®Anaxdent®, Nexco®Ivoclar®, Solidex®Shofu®, Novo.lign®Bredent®, etc.) which incorporate ceramic fillings have been developed. Due to their molecular structure, these materials have excellent density and homogeneity [24]. The micro filling integrated into the polymer matrix increases abrasion resistance, at the...

Case presentation : Zirconia implants and peek res...

In terms of the load-cushioning capacity of the prosthetic elements, the use of PEEK as a prosthetic structure on implants has increased in recent years [14]. PEEK is a high-density thermoplastic polymer with a linear aromatic semi-crystalline structure that has exceptional physical and chemical properties as regards toughness, hardness and elasticity. Also, its low molecular weight, combined with...

Case presentation : Zirconia implants and peek res...

Fifteen days after surgery, the appearance of the soft tissue was excellent, with no signs of inflammation in the mucosa. The patient mentioned the absence of bleeding and pain during the post-operation period. At the same time, we made a clinical and radiological evaluation. Three months after surgery, the stumps of the implants were carved to improve their parallelism with a special diamond dril...

Case presentation : Zirconia implants and peek res...

A patient who is a 45-year-old woman and non-smoker has no medical record of interest. The patient complained of pain in the right second upper molar. She said that she felt intense pain while chewing. The pain was accentuated with occlusion and while chewing, making normal functioning impossible. The patient mentioned the absence of piece 16, which had been extracted 8 years previously. Clinica...

Background : Zirconia implants and peek restoratio...

In the field of implant dentistry, the most widely used implants over the past 40 years are those manufactured from titanium [1], which are still the most popular. The recent demands for materials without metal alloys in dentistry, together with the increased sensitivity and allergies of some patients, have promoted the development of new materials. An example of this is zirconia-based dental i...

Abstract : Zirconia implants and peek restorations...

One of the disadvantages of the zirconia implants is the lack of elasticity, which is increased with the use of ceramic or zirconia crowns. The consequences that could result from this lack of elasticity have led to the search for new materials with improved mechanical properties. A patient who is a 45-year-old woman, non-smoker and has no medical record of interest with a longitudinal fracture i...

Fig. 4. Comparative illustration of mean ISQ value...

Fig. 4. Comparative illustration of mean ISQ values Fig. 4. Comparative illustration of mean ISQ values

Fig. 3. Implants were placed after application of ...

Fig. 3. Implants were placed after application of CGF membrane Fig. 3. Implants were placed after application of CGF membrane

Fig. 2. CGF membrane was applied in study group im...

Fig. 2. CGF membrane was applied in study group implant sockets Fig. 2. CGF membrane was applied in study group implant sockets

Fig. 1. CGF was obtained after centrifugation : Ev...

Fig. 1. CGF was obtained after centrifugation Fig. 1. CGF was obtained after centrifugation

Table 3 Mean ISQ value changes between study and c...

  Control group Study group Immediate–1st week −2.25 ± 1.713 1.40 ± 1.847 Immediate–4th wee...

Table 2 Mean ISQ values in the study and control g...

  Control group Study group Immediate 75.75 ± 5.552 78.00 ± 2.828 1st week ...

Table 1 Demographic data of patients : Evaluation ...

Case no. Age Sex Group Implant number 1 20 ...

About this article : Evaluation of effectiveness o...

Pirpir, C., Yilmaz, O., Candirli, C. et al. Evaluation of effectiveness of concentrated growth factor on osseointegration. Int J Implant Dent 3, 7 (2017). https://doi.org/10.1186/s40729-017-0069-3 Download citation Received: 16 December 2016 Accepted: 16 February 2017 Published: 03 March 2017 DOI: https://doi.org/10.1186/s40729-017-0069-3

Rights and permissions : Evaluation of effectivene...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Evaluation of effectiveness o...

Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Karadeniz Technical University, Trabzon, Turkey Cagasan Pirpir, Onur Yilmaz, Celal Candirli & Emre Balaban You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in ...

References : Evaluation of effectiveness of concen...

Prakash S, Thakur A. Platelet concentrates: past, present and future. J Maxillofac Oral Surg. 2011;10(1):45–9. Rodella LF, Favero G, Boninsegna R, Buffoli B, Labanca M, Scari G, et al. Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fraction. Microsc Res Tech. 2011;74(8):772–7. Ademokun JA, Chapman C, Dunn J, Lander D, Mair K, Proctor SJ, et al...

References : Evaluation of effectiveness of concen...

Huwiler MA, Pjetursson BE, Bosshardt DD, Salvi GE, Lang NP. Resonance frequency analysis in relation to jawbone characteristics and during early healing of implant installation. Clin Oral Implants Res. 2007;18(3):275–80. Kroese-Deutman HC, Vehof JW, Spauwen PH, Stoelinga PJ, Jansen JA. Orthotopic bone formation in titanium fiber mesh loaded with platelet-rich plasma and placed in segmental defe...

References : Evaluation of effectiveness of concen...

Nurden AT, Nurden P, Sanchez M, Andia I, Anitua E. Platelets and wound healing. Front Biosci. 2008;13:3532–48. Anitua E, Sanchez M, Zalduendo MM, de la Fuente M, Prado R, Orive G, et al. Fibroblastic response to treatment with different preparations rich in growth factors. Cell Prolif. 2009;42(2):162–70. He L, Lin Y, Hu X, Zhang Y, Wu H. A comparative study of platelet-rich fibrin (PRF) and ...

References : Evaluation of effectiveness of concen...

Raghavendra S, Wood MC, Taylor TD. Early wound healing around endosseous implants: a review of the literature. Int J Oral Maxillofac Implants. 2005;20(3):425–31. Oncu E, Bayram B, Kantarci A, Gulsever S, Alaaddinoglu EE. Positive effect of platelet rich fibrin on osseointegration. Med Oral Patol Oral Cir Bucal. 2016;21(5):e601–7. Anitua E. Plasma rich in growth factors: preliminary results o...

Abbreviations : Evaluation of effectiveness of con...

Bone morphogenetic protein Concentrated growth factor Computed tomography Insulin-like growth factor Platelet-derived growth factor Platelet-rich fibrin Platelet-rich plasma Resonance frequency analysis Transforming growth factor-β1 Transforming growth factor-β2 Vascular endothelial growth factor

Conclusions : Evaluation of effectiveness of conce...

Considering this data, it appears that application of CGF enhanced stability of implants and accelerated osseointegration in the early period. CGF has positive effects on the ISQ value at the first week and fourth week. Further laboratory studies are needed to demonstrate the positive effects of blood products on the osseointegration process at the histopathological level.

Discussion : Evaluation of effectiveness of concen...

In a study by Monov et al. using PRP around the implant, a higher stability value was obtained in the study group during the early recovery period (6 weeks) although difference between the groups was not statistically significant [23]. Kim et al. reported in a study that there was a statistically significant increase in bone-implant contact with PRP administration in the vicinity of the implant [...

Discussion : Evaluation of effectiveness of concen...

Introduced in 1998 by Marx, PRP is used in oral and maxillofacial surgeries to speed up the recovery of grafts in bone-grafted areas [14, 26–30]. Although many studies have shown that platelet-rich plasma affects bone healing positively, the results of some other studies suggest otherwise [31, 32]. In recent years, the platelet-rich fibrin (PRF) was described by Choukroun as a second-generation...

Discussion : Evaluation of effectiveness of concen...

Implant stability is one of the important parameters that assess the loading time and dental implant success. Investigators have recommended that implants with ISQ 

Results : Evaluation of effectiveness of concentra...

The study includes 12 patients (5 males, 7 females). Patients participating in the study are between 20–68 years of age and the mean age is 44 years. A total of 40 implants were placed, 20 of these were included in the study group (50%), and the other 20 were included in the control group (50%). Twenty-one implants were placed in type 2 bone, 19 implants in type 3 bone (Table 1). The distribu...

Methods : Evaluation of effectiveness of concentra...

Independent sample t test was applied between the two groups by taking the differences between the data obtained in these periods. Two-way ANOVA and Fisher’s LSD test was used for evaluating the associations among group and insertion torque. A value of p 

Methods : Evaluation of effectiveness of concentra...

All surgical procedures were performed under local anesthesia by the same surgeon. A full-thickness mucoperiosteal flap was removed by incision on the alveolar crest. Implant cavities were prepared according to the surgical protocol of the Bego Semados implant system (BEGO Implant Systems GmbH & Co. KG, Bremen, Germany). The final osteotomy diameters were the same as the placed implants. In the st...

Methods : Evaluation of effectiveness of concentra...

This study was conducted in compliance with the principles of the Declaration of Helsinki, and approval of the ethics committee required for the study was obtained from the Ethics Committee of the Karadeniz Technical University (2015/21). The procedures to be performed were explained in detail and patients signed the consent forms. The study was carried out on individuals who applied to Karadeniz ...

Background : Evaluation of effectiveness of concen...

That the implant has sufficient stability after placement is important for providing the necessary bone formation around the implant and for the optimal distribution of functional forces at the implant-bone interface during healing [15–17]. It can be said that resonance frequency analysis (RFA) is a very important tool for tracking the osseointegration process [18, 19]. RFA is a technique that ...

Background : Evaluation of effectiveness of concen...

Osseointegration of dental implants is important for long-term success and stability. There is no standardization in terms of the time of osseointegration and the timing of prosthetic loading. This process varies between 0–6 months [1]. Various strategies are being explored to shorten this period. Changes in implant surface properties and design have increased primer stability and helped the pe...

Abstract : Evaluation of effectiveness of concentr...

Growth factor-containing products have been reported to increase implant stability and accelerate osseointegration. Concentrated growth factor (CGF) can be used for this purpose with the growth factors it contains. The aim of this study is to assess the effect of CGF on implant stability and osseointegration. Twelve patients with maxillary anterior toothless were included in the study. Implant ca...

About this article : Short-term follow-up of masti...

Tanaka, M., Bruno, C., Jacobs, R. et al. Short-term follow-up of masticatory adaptation after rehabilitation with an immediately loaded implant-supported prosthesis: a pilot assessment. Int J Implant Dent 3, 8 (2017). https://doi.org/10.1186/s40729-017-0070-x Download citation Received: 24 October 2016 Accepted: 23 February 2017 Published: 07 March 2017 DOI: https://doi.o...

Rights and permissions : Short-term follow-up of m...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Short-term follow-up of masti...

Department of Prosthetic Dentistry, Graduate School of Biomedical Science, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan Mihoko Tanaka, Tetsurou Torisu & Hiroshi Murata Centre for Periodontology and Implantology Leuven, IJzerenmolenstraat 110, B-3001, Heverlee, Belgium Mihoko Tanaka & Collaert Bruno OMFS IMPATH, Department of Imaging & Pathology, University of Leuven, Kap...

Acknowledgements : Short-term follow-up of mastica...

The authors are grateful to the volunteers who participated in this study. This work was supported by JSPS Grant-in-Aid for Scientific Research (C), grant number 23592860. MT, CB, and RJ conceived and designed the experiment. MT and CB performed the experiments and analyzed the data with R J. TT and HM helped to draft the manuscript. All authors read and approved the final manuscript. Mihoko Tan...

References : Short-term follow-up of masticatory a...

Collaert B, Wijnen L, De Bruyn H. A 2-year prospective study on immediate loading with fluoride-modified implants in the edentulous mandible. Clin Oral Implants Res. 2011;22:1111–6. Collaert B, De Bruyn H. Immediate functional loading of TiOblast dental implants in full-arch edentulous maxillae: a 3-year prospective study. Clin Oral Implants Res. 2008;19:1254–60. Matsui Y, Ohno K, Michi K, S...

References : Short-term follow-up of masticatory a...

Bakke M, Holm B, Gotfredsen K. Masticatory function and patient satisfaction with implant-supported mandibular overdentures: a prospective 5-year study. Int J Prosthodont. 2002;15:575–81. Miyaura K, Morita M, Matsuka Y, Yamashita A, Watanabe T. Rehabilitation of biting abilities in patients with different types of dental prostheses. J Oral Rehabil. 2000;27:1073–6. Peyron MA, Blanc O, Lund JP...

References : Short-term follow-up of masticatory a...

Trulsson M, Johansson RS. Encoding of amplitude and rate of forces applied to the teeth by human periodontal mechanoreceptive afferents. J Neurophysiol. 1994;72:1734–44. Hidaka O, Morimoto T, Masuda Y, Kato T, Matsuo R, Inoue T, et al. Regulation of masticatory force during cortically induced rhythmic jaw movements in the anesthetized rabbit. J Neurophysiol. 1997;77:3168–79. Hidaka O, Morimo...

References : Short-term follow-up of masticatory a...

Klineberg IJ, Trulsson M, Murray GM. Occlusion on implants—is there a problem? J Oral Rehabil. 2012;39:522–37. Feine J, Jacobs R, Lobbezoo F, Sessle BJ, Van Steenberghe D, Trulsson M, Fejerskov O, Svensson P. A functional perspective on oral implants—state-of-the-science and future recommendations. J Oral Rehabil. 2006;33:309–12. Jacobs R, van Steenberghe D, Naert I. Masseter muscle fati...

Conclusions : Short-term follow-up of masticatory ...

The present pilot study could not confirm an immediate rise in bite force after implant rehabilitation. Instead, improvements were mainly noted up to 3 months after surgery and rehabilitation. Furthermore, it became evident that despite gradually improved bite force in all patients, masticatory efficiency and food hardness perception did not necessarily follow the same trend. The present findings...

Discussion : Short-term follow-up of masticatory a...

Occlusal contact was significantly increased 3 months after implant rehabilitation when compared to stage one (prior to implant rehabilitation). We assumed the reason was that some participant’s occlusion was worn down because the material of provisional restoration was resin. To observe the adaptation of masticatory function after rehabilitation with an immediately loaded implant-supported pro...

Results : Short-term follow-up of masticatory adap...

Hardness perception became better after implant rehabilitation, with a reduction of the error rate by 16% (Fig. 3). While five out of eight participants performed better in this test after rehabilitation, the results in the others were less clear. More detailed analysis showed that, despite wearing dentures, four participants were 100% successful in recognition of hardness before implant surgery,...

Results : Short-term follow-up of masticatory adap...

Two participants were unavailable to attend the testing at 1–2 weeks after the provisional restoration had been inserted, which resulted in missing data. Overall descriptive analyses yielded the following observations for the four tests. Occlusal contact and approximate maximum bite force were significantly increased 3 months after implant rehabilitation because of the adjustment of provisio...

Methods : Short-term follow-up of masticatory adap...

To assess the hardness differences, the examiner placed each test specimen on the tongue with chopsticks, and then the participants chewed on all sides and swallowed. They were asked to remember the hardness of the first specimen, which always had medium hardness and served as a control, and then to determine the level of hardness (hard, medium, or soft) of four consecutive and randomly administer...

Methods : Short-term follow-up of masticatory adap...

To assess the masticatory efficiency, we used glucose extraction in the filtrate obtained after chewing the specimen. After rinsing the mouth with tap water, a gum-like specimen mixed with 5% glucose with a height of 10 mm (Glucosensor Gummy, GC, Tokyo, Japan) was placed on patient’s tongue with chopsticks. Patients were requested to chew on the cube for 20 s, after which, they expectorated al...

Methods : Short-term follow-up of masticatory adap...

Six females and 2 males (average age 66.4 years, range 52–85 years) with upper (n = 7) or lower (n = 1) complete dentures participated in this study. Inclusion criteria were (1) an opposite jaw that included natural dentition at least to the second premolar on both sides, (2) a need for fixed rehabilitation, (3) no medical contraindication to the placement of implants, (4) no need for ...

Background : Short-term follow-up of masticatory a...

The purpose of this pilot investigation was to use testing methodologies involving four aspects of masticatory adaptation after rehabilitation with an immediately loaded implant-supported prosthesis and to observe the recovery of each aspect respectively. Our hypothesis is that bite force may recover quickly, but other aspects will require monitoring and recording in order to form an overall judgm...

Background : Short-term follow-up of masticatory a...

In addition, it also remains to be demonstrated how a potential compensatory mechanism might work, with one of the options being osseoperception [2, 18–23]. In this context, it is also important to consider the adaptation time needed after oral rehabilitation. Some studies have performed longitudinal evaluations of masticatory function for more than 3 years [24, 25]. However, there are limited ...

Background : Short-term follow-up of masticatory a...

Tooth loss represents a major oral disability comparable to an amputation, with severe impairment of oral functions [1]. While denture wearers can rely on mucosal sensors, anchoring prosthetic teeth to the bone via osseointegrated implants has been assumed to create a (partial) sensory substitution for missing periodontal ligament receptors from stimuli transmitted via the bone [2]. The restoratio...

Abstract : Short-term follow-up of masticatory ada...

When teeth are extracted, sensory function is decreased by a loss of periodontal ligament receptions. When replacing teeth by oral implants, one hopes to restore the sensory feedback pathway as such to allow for physiological implant integration and optimized oral function with implant-supported prostheses. What remains to be investigated is how to adapt to different oral rehabilitations. The pur...

About this article : A novel report on the use of ...

Dattani, A., Richardson, D. & Butterworth, C.J. A novel report on the use of an oncology zygomatic implant-retained maxillary obturator in a paediatric patient. Int J Implant Dent 3, 9 (2017). https://doi.org/10.1186/s40729-017-0073-7 Download citation Received: 24 November 2016 Accepted: 26 February 2017 Published: 28 March 2017 DOI: https://doi.org/10.1186/s40729-017-00...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : A novel report on the use of ...

Oral and Maxillofacial Surgery, Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, UK Amit Dattani Maxillofacial Surgery, Regional Craniofacial Unit, Alder Hey Children’s Hospital, Liverpool, UK David Richardson Maxillofacial Prosthodontics, Regional Maxillofacial Unit, University Hospital Aintree, Longmoor Lane, Liverpool, L9 7AL, UK Chris J. Butterworth You can also sea...

References : A novel report on the use of an oncol...

Brown JS, Shaw RJ. Reconstruction of the maxilla and midface: introducing a new classification. Lancet Oncol. 2010;11(10):1001–8. Breeze J, Rennie A, Morrison A, Dawson D, Tipper J, Rehman K, et al. Health-related quality of life after maxillectomy: obturator rehabilitation compared with flap reconstruction. Br J Oral Maxillofac Surg. 2016;54(8):857–62. Kim SM, Park MW, Cho YA, Myoung H, Lee...

Conclusions : A novel report on the use of an onco...

The use of zygomatic implants to supplement the stability and retention of the maxillary obturator in this case has improved the function of the prosthesis and provided for a very high-quality rehabilitation for the patient reported with no evidence of disruption to facial growth in the 22 months following surgery.

Discussion : A novel report on the use of an oncol...

The use of modified zygomatic implants (Fig. 1) allows improved hygiene by the patient of the implants within the maxillary defect. The threaded portion of the implants is fully engaged into the bone with only the smooth portion protruding into the defect. Clearly this ongoing hygiene by the patient is of utmost importance in preventing peri-implant soft and hard tissue changes, but the implant d...

Discussion : A novel report on the use of an oncol...

The difficulty of restoration with a maxillary obturator prosthesis depends on the extent of the surgical resection, with the acceptance that resections with an increasing horizontal component provide a much greater prosthodontic challenge. The number of remaining teeth is a key component in conventional obturator design [9] with the remaining dentition being used exclusively to retain the prosthe...

Discussion : A novel report on the use of an oncol...

The paediatric population rarely suffer malignant disease of the oral cavity requiring any form of maxillectomy, and there is little published evidence around the rehabilitation and restorative management of children undergoing such procedures. The seemingly most common approach for a limited low-level maxillary resection in a child would be to consider resection and simple prosthetic obturation a...

Case presentation : A novel report on the use of a...

Four weeks later, the patient was returned to the operating room for removal and modification of the obturator. The cavity was healing well, and both implants were firm with no evidence of infection. The initial obturator was modified with the application of a soft lining material and the patient subsequently discharged with instructions on the insertion and removal of the obturator. At the 12-we...

Case presentation : A novel report on the use of a...

A medically fit and well 13-year 11-month-old male was referred to the oral and maxillofacial surgery department at Alder Hey Children’s Hospital in Liverpool in regard to an intra-oral swelling of the right palatal region (Fig. 2). An incisional biopsy was initially reported as a pleomorphic adenoma of the premolar region. Subsequently, a CT scan showed no significant bony abnormality, and a w...

Background : A novel report on the use of an oncol...

The characteristics of a good obturator will improve swallowing, speech function, minimise nasal fluid leakage from the antrum and nasal spaces, restore facial aesthetics including the teeth and facilitate masticatory function and speech. A surgical obturator can be provided at the time of surgery to facilitate function and haemostasis in the immediate post-operative period, and this can subsequen...

Background : A novel report on the use of an oncol...

Maxillary defects of acquired [1] or congenital origin produce a communication between the oral and nasal cavities sometimes via an opening into the maxillary antrum and by direct communication into the nose. This in turn can result in masticatory compromise, swallowing and speech impairment, nasal fluid regurgitation and aesthetic concerns. The management of the maxillectomy patient is a complex ...

Abstract : A novel report on the use of an oncolog...

This report details the use of zygomatic oncology osseointegrated implants to support and retain a maxillary obturator in a 13-year-old male patient who underwent a right-sided hemi-maxillectomy (Brown Class 2b) (Brown and Shaw, Lancet Oncol 11:1001–8, 2010) for a myxoid spindle cell carcinoma. At the time of maxillary resection, two zygomatic oncology implants were inserted into the right zygom...

About this article : Treatment with teriparatide f...

Zushi, Y., Takaoka, K., Tamaoka, J. et al. Treatment with teriparatide for advanced bisphosphonate-related osteonecrosis of the jaw around dental implants: a case report. Int J Implant Dent 3, 11 (2017). https://doi.org/10.1186/s40729-017-0074-6 Download citation Received: 06 December 2016 Accepted: 12 February 2017 Published: 30 March 2017 DOI: https://doi.org/10.1186/s4...

Rights and permissions : Treatment with teriparati...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Treatment with teriparatide f...

Department of Oral and Maxillofacial Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan Yusuke Zushi, Kazuki Takaoka, Joji Tamaoka, Miho Ueta, Kazuma Noguchi & Hiromitsu Kishimoto You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Schola...

References : Treatment with teriparatide for advan...

Stanton DC, Balasanian E. Outcome of surgical management of bisphosphonate-related osteonecrosis of the jaws: review of 33 surgical cases. J Oral Maxillofac Surg. 2009;67:943–50.Carlson ER, Basile JD. The role of surgical resection in the management of bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2009;67:85–95.Wilde F, Heufelder M, Winter K, et al. The role of surg...

References : Treatment with teriparatide for advan...

Stanton DC, Balasanian E. Outcome of surgical management of bisphosphonate-related osteonecrosis of the jaws: review of 33 surgical cases. J Oral Maxillofac Surg. 2009;67:943–50. Carlson ER, Basile JD. The role of surgical resection in the management of bisphosphonate-related osteonecrosis of the jaws. J Oral Maxillofac Surg. 2009;67:85–95. Wilde F, Heufelder M, Winter K, et al. The role of ...

References : Treatment with teriparatide for advan...

Grant BT, Amenedo C, Freeman K, Kraut RA. Outcomes of placing dental implants in patients taking oral bisphosphonates: a review of 115 cases. J Oral Maxillofac Surg. 2008;66:223–30. Goss A, Bartold M, Sambrook P, Hawker P. The nature and frequency of bisphosphonate-associated osteonecrosis of the jaws in dental implant patients: a South Australian case series. J Oral Maxillofac Surg. 2010;68:33...

References : Treatment with teriparatide for advan...

Marx RE. Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg. 2003;61:1115–7. Marx RE, Sawatari J, Fortin M, et al. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis) of the jaws; risk factors, recognition, prevention, and treatment. J Oral Maxillofac Surg. 2005;63:1567. Harper RP, Fung E. Resolution of...

Conclusions : Treatment with teriparatide for adva...

We have reported a case of a severely osteoporotic elderly woman with BRONJ around her dental implants, who was treated successfully with teriparatide. Teriparatide therapy appeared to exert beneficial effects in this patient.

Discussion : Treatment with teriparatide for advan...

It is therefore important that all patients treated with oral BPs must be given a full explanation of the potential risks of implant failure and BRONJ development in the short and long term. Because the potential role of infection in implant failure and BRONJ occurrence is still debated, great attention should be paid to the long-term oral hygiene and plaque control of implant-prosthetic restorati...

Discussion : Treatment with teriparatide for advan...

We describe a case of a patient with a 6-year history of alendronate therapy, in which BRONJ developed around her dental implants. In this patient, the dental implants achieved successful osseointegration, and BRONJ occurred after the second surgery. Several factors could have played a role in the development of BRONJ in this patient. Glucocorticoid therapy is associated with an increased risk of ...

Case presentation : Treatment with teriparatide fo...

In November 2011, after a consultation with an osteoporosis expert at the Orthopedic Medicine Clinic of our hospital, alendronate therapy was stopped and subcutaneous teriparatide therapy at a dose of 20 μg per day was started. During the course of the teriparatide therapy, the patient continued to use 0.02% benzalkonium chloride solution for local irrigation. In April 2012, after 5 months of ...

Case presentation : Treatment with teriparatide fo...

A 66-year-old woman was referred to the Oral and Maxillofacial Surgery Clinic at Hyogo College of Medicine Hospital, Japan, in September 2011, for an extraoral fistula and refractory pain of the right mandible associated with a purulent discharge and soft tissue swelling. The patient’s osteoporosis was diagnosed in 2005 and treated with 35 mg of alendronate weekly by the family doctor. The pati...

Background : Treatment with teriparatide for advan...

Oral bisphosphonates (BPs) are used to treat osteoporosis, Paget’s disease, and osteogenesis imperfecta. They are most widely used for treatment of osteoporosis. BP-related osteonecrosis of the jaw (BRONJ) was first reported by Marx in 2003 [1]. The risk of BRONJ in osteoporotic patients treated with BPs remains low compared with that of oncology patients [2]. Recent studies have indicated that ...

Abstract : Treatment with teriparatide for advance...

We report a case of a 66-year-old severely osteoporotic woman with bisphosphonate-related osteonecrosis of the jaw (BRONJ) around her dental implants, who was treated successfully with teriparatide and sequestrectomy of the mandible. After 5 months of teriparatide therapy, the sequestrum separation had progressed and a sequestrectomy was performed under general anesthesia. Five months after the o...

Fig. 6. Micro CT scan images of the MDIs and Ankyl...

Fig. 6. Micro CT scan images of the MDIs and Ankylos® embedded in rabbit bone 6 weeks post implantation Fig. 6. Micro CT scan images of the MDIs and Ankylos® embedded in rabbit bone 6 weeks post implantation

Fig. 5. Histological section of standard implant i...

Fig. 5. Histological section of standard implant in rabbit tibia stained with methylene blue and basic fuchsin Fig. 5. Histological section of standard implant in rabbit tibia stained with methylene blue and basic fuchsin

Fig. 4. Histological section of mini dental implan...

Fig. 4. Histological section of mini dental implant in rabbit tibia stained with methylene blue and basic fuchsin Fig. 4. Histological section of mini dental implant in rabbit tibia stained with methylene blue and basic fuchsin

Fig. 3. Histological sections being obtained with ...

Fig. 3. Histological sections being obtained with Leica SP 1600 saw microtome Fig. 3. Histological sections being obtained with Leica SP 1600 saw microtome

Fig. 2. Leica SP 1600 saw microtome : Osseointegra...

Fig. 2. Leica SP 1600 saw microtome Fig. 2. Leica SP 1600 saw microtome

Fig. 1. Radiograph showing implants in the rabbit ...

Fig. 1. Radiograph showing implants in the rabbit tibia Fig. 1. Radiograph showing implants in the rabbit tibia

Table 2 Descriptive statistics of the experimental...

BIC 3M™ ESPE™ MDIs Ankylos® Friadent (Dentsply) Median 58.5 57 ...

Table 1 Comparison of % BIC in both groups : Osseo...

Sample 3M™ESPE™ MDIs Ankylos® 1. 67 54 2. ...

About this article : Osseointegration of standard ...

Dhaliwal, J.S., Albuquerque, R.F., Murshed, M. et al. Osseointegration of standard and mini dental implants: a histomorphometric comparison. Int J Implant Dent 3, 15 (2017). https://doi.org/10.1186/s40729-017-0079-1Download citationReceived: 22 February 2017Accepted: 26 April 2017Published: 01 May 2017DOI: https://doi.org/10.1186/s40729-017-0079-1

About this article : Osseointegration of standard ...

Dhaliwal, J.S., Albuquerque, R.F., Murshed, M. et al. Osseointegration of standard and mini dental implants: a histomorphometric comparison. Int J Implant Dent 3, 15 (2017). https://doi.org/10.1186/s40729-017-0079-1 Download citation Received: 22 February 2017 Accepted: 26 April 2017 Published: 01 May 2017 DOI: https://doi.org/10.1186/s40729-017-0079-1

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional information : Osseointegration of stand...

This article was ammended to correct discrpencies in the Abstract. An erratum has also been published for this manuscript. An erratum to this article is available at http://dx.doi.org/10.1186/s40729-017-0088-0.

Author information : Osseointegration of standard ...

Faculty of Dentistry, McGill University, 2001 McGill College Avenue, Suite 500, Montreal, Quebec, H3A 1G1, Canada Jagjit S. Dhaliwal, Monzur Murshed & Jocelyne S. Feine Faculty of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil Rubens F. Albuquerque Jr Department of Medicine, McGill University, Montreal, Quebec, Canada Monzur Murshed You can also search...

References : Osseointegration of standard and mini...

Schwartz Z, Lohmann CH, Oefinger J, Bonewald LF, Dean DD, Boyan BD. Implant surface characteristics modulate differentiation behavior of cells in the osteoblastic lineage. Adv Dent Res. 1999;13:38–48. Boyan BD, Lossdorfer S, Wang L, Zhao G, Lohmann CH, Cochran DL, et al. Osteoblasts generate an osteogenic microenvironment when grown on surfaces with rough microtopographies. Eur Cell Mater. 2003...

References : Osseointegration of standard and mini...

Hayakawa T, Yoshinari M, Kiba H, Yamamoto H, Nemoto K, Jansen JA. Trabecular bone response to surface roughened and calcium phosphate (Ca-P) coated titanium implants. Biomaterials. 2002;23(4):1025–31. Sul YT, Byon ES, Jeong Y. Biomechanical measurements of calcium-incorporated oxidized implants in rabbit bone: effect of calcium surface chemistry of a novel implant. Clin Implant Dent Relat Res. ...

References : Osseointegration of standard and mini...

Park JW, Kim HK, Kim YJ, An CH, Hanawa T. Enhanced osteoconductivity of micro-structured titanium implants (XiVE S CELLplus) by addition of surface calcium chemistry: a histomorphometric study in the rabbit femur. Clin Oral Implants Res. 2009;20(7):684–90. Yang GL, He FM, Yang XF, Wang XX, Zhao SF. Bone responses to titanium implants surface-roughened by sandblasted and double etched treatments...

References : Osseointegration of standard and mini...

Buser D, Schenk RK, Steinemann S, Fiorellini JP, Fox CH, Stich H. Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs. J Biomed Mater Res. 1991;25(7):889–902. Gotfredsen K, Wennerberg A, Johansson C, Skovgaard LT, Hjorting-Hansen E. Anchorage of TiO2-blasted, HA-coated, and machined implants: an experimental study with rabbi...

References : Osseointegration of standard and mini...

Trisi P, Lazzara R, Rao W, Rebaudi A. Bone-implant contact and bone quality: evaluation of expected and actual bone contact on machined and osseotite implant surfaces. Int J Periodontics Restorative Dent. 2002;22(6):535–45. Froum SJ, Simon H, Cho SC, Elian N, Rohrer MD, Tarnow DP. Histologic evaluation of bone-implant contact of immediately loaded transitional implants after 6 to 27 months. In...

References : Osseointegration of standard and mini...

Hong RK, Heo JM, Ha YK. Lever-arm and mini-implant system for anterior torque control during retraction in lingual orthodontic treatment. Angle Orthod. 2005;75(1):129–41. Mazor Z, Steigmann M, Leshem R, Peleg M. Mini-implants to reconstruct missing teeth in severe ridge deficiency and small interdental space: a 5-year case series. Implant Dent. 2004;13(4):336–41. Siddiqui AA, Sosovicka M, Go...

References : Osseointegration of standard and mini...

Branemark PI, Adell R, Breine U, Hansson BO, Lindstrom J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3(2):81–100. Boerrigter EM, Stegenga B, Raghoebar GM, Boering G. Patient satisfaction and chewing ability with implant-retained mandibular overdentures: a comparison with new complete dentures with or without preprosthetic ...

Conclusions : Osseointegration of standard and min...

The results of this study show that MDIs as well as regular implants osseointegrate in rabbits.

Discussion : Osseointegration of standard and mini...

Our study is also in concordance with the results of a removal torque study by Simon et al. [63] in immediately loaded “transitional endosseous implants” in humans. The percentage BIC for MDIs was similar to standard implants. The surface topography also affects the BIC, Wennerberg et al. [32] measured and compared removal torque values on screw-shaped titanium implants with three surface typ...

Discussion : Osseointegration of standard and mini...

The osseointegration potential of 3M™ESPE™ MDIs has not been studied. The MDI is a one-piece implant that simplifies the restorative phase resulting in a reduced cost for the patient. Titanium-aluminum-vanadium alloy (Ti 6Al-4V-ELI) is used for increased strength. The success of these implants led to its use in long-term fixed and removable dental prostheses [51]. Conventional implant treatmen...

Results : Osseointegration of standard and mini de...

On the whole, postoperative wound healing in all the rabbits was good. None of them exhibited any signs of wound infection or exposure. A total of 36 specimens were retrieved for histological examination. All of the implants in both groups showed osseointegration and displayed a good amount of bone contact length (Figs. 4 and 5). No discernible differences were noticed between both the groups. T...

Methods : Osseointegration of standard and mini de...

The saw blade has a thickness of 280 μm and a feed of 310 μm was selected to obtain the final section thickness of 30 μm. The knurled screw was used for the setting of the section thickness. The prepared section was finally removed from the saw blade. The specimens were prepared for histology by the method as described by Donath and Breuner [49]. Subsequently, the sections were stained with...

Methods : Osseointegration of standard and mini de...

The specimens were dehydrated in the ascending graded ethanol solution and kept in a pre-filtration solution for 3 h at room temperature and then in the filtration solution at 4 °C for 17 h. The specimens were then embedded in a light curing resin Technovit 9100 NEW (Kulzer & Co., Wehrheim, Germany) polymerization system based on methyl methacrylate, specially developed for embedding mineraliz...

Methods : Osseointegration of standard and mini de...

Expected length of the procedure was approximately 1 h. Following placement of the implants, the wound was sutured in layers. The underlying muscle, fascia, and dermal layers were sutured with the help of Vicryl (Polyglactin 910) suture with 3/8 circle reverse cutting needle. The skin was sutured to a primary closer with the same suture material. Plain X-ray images of all the rabbit tibia were t...

Methods : Osseointegration of standard and mini de...

A small longitudinal skin incision just distal to the tibia-femur joint was made. The tibia/femur head was exposed subperiosteally and an osteotomy performed with the delicately placed pilot drill over the entry point and lightly pumped up and down under copius saline irrigation just to enter the cortical bone for the MDIs. This was used for initial bone drilling to depth of 0.5 mm. The 3M™ESPE...

Methods : Osseointegration of standard and mini de...

Nine clinically healthy New Zealand white rabbits weighing 3.5 kg and more were used for the study, and the animals were housed in the central animal house facility. The head of tibia/femur of the animals were used for the implantation of samples. Rabbits’ tibiae and femur have been widely used as an animal model by various other authors to study osseointegration of dental implants [36–45]. ...

Background : Osseointegration of standard and mini...

Despite the advantages of the mini dental implants, evidence on their efficacy and long-term success is lacking. The success of these implants will depend on their union with the surrounding bone. New implant systems entering into the market have to be studied with the help of animal models first, to demonstrate the osseointegration potential for their probable success in humans. There is a limite...

Background : Osseointegration of standard and mini...

The term “osseointegration” was first introduced to explain the phenomenon for stable fixation of titanium to bone by Brånemark et al. in the 1960s [1]. Osseointegrated implants were introduced, a new era in oral rehabilitation began, and many studies were conducted [2, 3]. A success rate of over 90% has been reported [4, 5]. Further, a success rate of 81% in the maxillary bone and 91% in the...

Abstract : Osseointegration of standard and mini d...

Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit model. Nine New Zealand ...

Fig. 3. Mean bone loss at 6 months and 1 year. M...

Fig. 3. Mean bone loss at 6 months and 1 year. Mean bone loss distribution charts at 6 months and 1 year present no statistically significant difference. p value at 6 months was 0.2981 and at 1 year 0.6613 Fig. 3. Mean bone loss at 6 months and 1 year. Mean bone loss distribution charts at 6 months and 1 year present no statistically significant difference. p value at 6 months was ...

Fig. 2. ISQ values at placement, 6 weeks, 6 mont...

Fig. 2. ISQ values at placement, 6 weeks, 6 months, and 1 year. Mean and standard deviation of ISQ values taken at placement, 6 weeks, 6 months, and 1 year is presented. No statistical significant difference was determined between ISQ values at all time points. (p 

Fig. 1. Implant design. The OSPTX and OSP implants...

Fig. 1. Implant design. The OSPTX and OSP implants are manufactured from high-grade commercially pure titanium with surface roughness produced via a fluoride treatment process. The OSP implant is a screw-shaped self-tapping implant. The diameter used in this study was 4.0 mm. The implant length used in this study was 8 mm. The OSPTX implant has the same features as the OSP except the apex of t...

Table 2 Outcome success criteria : Comparative eva...

Implant success Clinically immobile when tested manually and/or with RFA (minimum ISQ = 65) Absence of peri-implant radiolucency present on an undistorted radiograph Absence of unresolved pain, discomfort, inf...

Table 1 Patient selection criteria : Comparative e...

Inclusion Male or female At least 18 years old Healthy enough to undergo routine implant surgery and subsequent dental treatment Partially edentulous requiring...

About this article : Comparative evaluation of the...

Simmons, D.E., Maney, P., Teitelbaum, A.G. et al. Comparative evaluation of the stability of two different dental implant designs and surgical protocols—a pilot study. Int J Implant Dent 3, 16 (2017). https://doi.org/10.1186/s40729-017-0078-2 Download citation Received: 18 January 2017 Accepted: 22 April 2017 Published: 02 May 2017 DOI: https://doi.org/10.1186/s40729-01...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Comparative evaluation of the...

Department of Periodontics, Louisiana State University Health Sciences Center School of Dentistry, 1100 Florida Avenue, New Orleans, LA, 70119, USA David E. Simmons, Pooja Maney, Austin G. Teitelbaum, Susan Billiot & A. Archontia Palaiologou Tulane University SPHTM, 1440 Canal St, Suite 2001, New Orleans, LA, 70130, USA Lomesh J. Popat You can also search for this author in ...

References : Comparative evaluation of the stabili...

De Bruyn H, Raes F, Cooper LF, Reside G, Garriga JS, Tarrida LG, et al. Three-years clinical outcome of immediate provisionalization of single Osseospeed() implants in extraction sockets and healed ridges. Clin Oral Implants Res. 2013;24(2):217–23. Ebler S, Ioannidis A, Jung RE, Hammerle CH, Thoma DS. Prospective randomized controlled clinical study comparing two types of two-piece dental impla...

References : Comparative evaluation of the stabili...

O'Sullivan D, Sennerby L, Meredith N. Influence of implant taper on the primary and secondary stability of osseointegrated titanium implants. Clin Oral Implants Res. 2004;15(4):474–80. Schwartz-Arad D, Herzberg R, Levin L. Evaluation of long-term implant success. J Periodontol. 2005;76(10):1623–8. Alves CC, Neves M. Tapered implants: from indications to advantages. Int J Periodontics Restora...

References : Comparative evaluation of the stabili...

Anitua E, Orive G. Short implants in maxillae and mandibles: a retrospective study with 1 to 8 years of follow-up. J Periodontol. 2010;81(6):819–26. Feldman S, Boitel N, Weng D, Kohles SS, Stach RM. Five-year survival distributions of short-length (10 mm or less) machined-surfaced and Osseotite implants. Clin Implant Dent Relat Res. 2004;6(1):16–23. Felice P, Cannizzaro G, Checchi V, March...

Notes : Comparative evaluation of the stability of...

DENTSPLY International, Susquehanna Commerce Center, 221 West Philadelphia Street, York, PA 17401 I-CAT 17 19; Imaging Services International LLC, 1910 North Penn Rd., Hatfield, PA 19440 Intra-Lock International, 6560 S. West Rogers Circle, Suite 24, Boca Raton, FL 33487 Osstell USA, 6700 Alexander Bell Drive, Suite 200, Columbia, MD 21046 ImageJ 1.50i Wayne Rasband National Institutes of Heal...

Conclusions : Comparative evaluation of the stabil...

Survival rates and stability of OSP and OSPTX implants was comparable. Osteotomy preparation either by the standard or by the soft bone surgical protocol had no significant effect on implant survival, success, and stability. Insertion torque presented a moderate to strong correlation with ISQ values at 6 weeks, 6 months, and 1 year. Insertion torque presented a weak correlation to ISQ values...

Discussion : Comparative evaluation of the stabili...

Insertion torque presented a moderate to strong correlation with ISQ values at 6 weeks, 6 months, and 1 year but not at time of implant insertion. This finding is in agreement with Acil et al. who reported no statistically significant correlation between insertion torque and ISQ at time of implant placement [22]. Although a strong correlation was found between insertion torque and bone loss at...

Discussion : Comparative evaluation of the stabili...

Augmentation of the maxillary sinus prior to dental implant placement is routinely performed in order to help patients restore their maxillary posterior dentition. Unfortunately, not all patients are candidates for this procedure due to either health, personal, or financial concerns. An alternative treatment without the need for a sinus elevation procedure is the use of a shorter implant. Research...

Results : Comparative evaluation of the stability ...

Overall implant survival rate was 93.3%. Two implants failed, one implant in group A (OSPTXSoft) and one in group B (OSPTXStd). Both implant failures occurred at the time of uncovery (at 6 weeks) and prior to loading of the implants and were attributed to lack of integration. With the exception of these two failed implants, there was 100% success for all remaining implants using the parameters de...

Methods : Comparative evaluation of the stability ...

ANOVA was used to compare the mean implant stabilities between the three groups. Post hoc testing was done via Tukey’s honestly significant differences test to calculate the differences between ISQ measurements at the time of implant placement, 6 weeks and 6 and 12 months (Fig. 2) as well as bone levels at 6 and 12 months (Fig. 3). The correlations of multiple parameters such as insertion t...

Methods : Comparative evaluation of the stability ...

Following proper approval by the LSUHSC Institution Review Board (LSUNO IRB#7438), 27 (30 implant sites) systemically healthy patients at least 18 years old were enrolled in the study and randomly divided into three groups as follows (inclusion and exclusion criteria are described in detail in Table 1): Group A received 10 OSPTX implants using the soft bone surgical protocol (OSPTXSoft). G...

Background : Comparative evaluation of the stabili...

A recent systematic review by Stocchero et al. concluded that an undersized drilling protocol in soft bone is an effective way to enhance insertion torque but recommended that further clinical studies are needed to confirm these data [18]. Our study was designed to address this question, as it compared the standard drilling protocol to a soft bone protocol. Our study hypothesis is that the stabil...

Background : Comparative evaluation of the stabili...

Dental implants are now a widely accepted treatment option for the replacement of missing teeth. The therapeutic goal of dental implants is to support restorations that replace single or multiple missing teeth so as to provide patient comfort, function, and esthetics as well as assist in the ongoing maintenance of remaining intraoral and perioral structures. However, anatomic limitations such as t...

Abstract : Comparative evaluation of the stability...

Survival and stability of OSPTX and OSP implants is comparable. Osteotomy preparation by either standard or soft bone surgical protocol presented no significant effect on implant survival and stability for the specific implant designs.

Abstract : Comparative evaluation of the stability...

The purpose of this study was to compare a parallel wall design implant to a tapered apex design implant when placed in the posterior maxilla using two different surgical protocols. Twenty-seven patients (30 implants) were divided into three groups. All implants were 4 mm wide in diameter and 8 mm long. Group A received 10 tapered implants (OSPTX) (Astra Tech OsseoSpeed TX™) using the soft b...

Fig. 7. a, b (The marginal discrepancy pattern for...

Fig. 7. and M4M). a Group CR (1: Ceramic surface, 2: CR surface) Units of the axis are in μm. b Group M4M (1: Ceramic surface, 2: M4M surface) Units of the axis are in μm Fig. 7. a, b (The marginal discrepancy pattern for group CR and M4M). a Group CR (1: Ceramic surface, 2: CR surface) Units of the axis are in μm. b Group M4M (1: Ceramic surface, 2: M4M surface) Units of the axis are in ...

Fig. 6. Access-hole filling surface areas measurem...

Fig. 6. Access-hole filling surface areas measurement, average Fig. 6. Access-hole filling surface areas measurement, average

Fig. 5. Depth and angle at the margin : Comparison...

Fig. 5. Depth and angle at the margin Fig. 5. Depth and angle at the margin

Fig. 4. Margin depth measurement localization (exa...

Fig. 4. Margin depth measurement localization (example: TRA, T = 12 M) Fig. 4. Margin depth measurement localization (example: TRA, T = 12 M)

Fig. 3. a–e (Filling surface changes): a (ROG, T...

Fig. 3.  1 M). c (ROG, T = 3 M). d (ROG, T = 6 M). e (ROG, T = 12 M) Fig. 3. a–e (Filling surface changes): a (ROG, T = 0). b (ROG, T = 1 M). c (ROG, T = 3 M). d (ROG, T = 6 M). e (ROG, T = 12 M)

Fig. 2. Occlusal contact point : Comparison of acc...

Fig. 2. Occlusal contact point Fig. 2. Occlusal contact point

Fig. 1. Brush-dip technique : Comparison of access...

Fig. 1. Brush-dip technique Fig. 1. Brush-dip technique

Table 4 Disappearance of the overfilling. Unit: % ...

  T = 1 M T = 3 M T = 6 M T = 12 M No disappearance CR 53.5% (15/28) ...

Table 3 Surface areas changes of access-hole filli...

  T = 1 M T = 3 M T = 6 M T = 12 M CR 100 93.2 87.6 ...

Table 2 Aesthetical Outcomes at T = 12 M (VAS...

Patients Position CR   Patients Position M4M   T = 0 T = 12 ...

Table 1 ᅟ : Comparison of access-hole filling ma...

Materials Product names Batch numbers Manufacturer Ceramic primer Super-bond UCP ...

About this article : Comparison of access-hole fil...

Tanimura, R., Suzuki, S. Comparison of access-hole filling materials for screw retained implant prostheses: 12-month in vivo study. Int J Implant Dent 3, 19 (2017). https://doi.org/10.1186/s40729-017-0076-4 Download citation Received: 14 December 2016 Accepted: 22 April 2017 Published: 05 May 2017 DOI: https://doi.org/10.1186/s40729-017-0076-4

Rights and permissions : Comparison of access-hole...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Comparison of access-hole fil...

8, place du Général Catroux, 75017, Paris, France Rémy Tanimura Department of Clinical Community and Sciences, University of Alabama at Birmingham School of Dentistry, 1919 7th Avenue South, Birmingham, AL, 35294-0007, USA Shiro Suzuki You can also search for this author in PubMed Google Scholar You can also search for this author in PubMe...

Acknowledgements : Comparison of access-hole filli...

The authors thank Sun Medical Corporation for their material supply. RT and SS carried out the clinical data and their analysis. RT and SS have been involved in drafting the manuscript and approved the final version to be published. The authors, Rémy Tanimura and Shiro Suzuki, declare that they have no financial, commercial or any other competing interests. Springer Nature remains neutral with...

Acknowledgements : Comparison of access-hole filli...

The authors thank Sun Medical Corporation for their material supply. RT and SS carried out the clinical data and their analysis. RT and SS have been involved in drafting the manuscript and approved the final version to be published. The authors, Rémy Tanimura and Shiro Suzuki, declare that they have no financial, commercial or any other competing interests. Springer Nature remains neutral with...

References : Comparison of access-hole filling mat...

de Pereira R P, Rocha CO, Reis JM, Arioli-Filho JN. Influence of sealing of the screw access hole on the fracture resistance of implant-supported restorations. Braz Dent J. 2016;27(2):148–52. Mihali S, Canjau S, Bratu E, Wang HL. Utilization of ceramic inlays for sealing implant prostheses screw access holes: a case-control study. Int J Oral Maxillofac Implants. 2016;31(5):1142–9. Download r...

References : Comparison of access-hole filling mat...

Taira Y, Sakai M, Sawase T. Effects of primer containing silane and thiophosphate monomers on bonding resin to a leucite-reinforced ceramic. J Dent. 2012;40(5):353–8. Kato H, Matsumura H, Tanaka T, Atsuta M. Bond strength and durability of porcelain bonding systems. J Prosthet Dent. 1996;75(2):163–8. Queiroz JR, Souza RO, Nogueira Junior Jr L, Ozcan M, Bottino MA. Influence of acid-etching a...

References : Comparison of access-hole filling mat...

Korsch M, Walther W. Peri-implantitis associated with type of cement: a retrospective analysis of different types of cement and their clinical correlation to the peri-implant tissue. Clin Implant Dent Relat Res. 2015;17(Suppl 2):e434–43. Linkevicius T, Vindasiute E, Puisys A, Linkeviciene L, Maslova N, Puriene A. The influence of the cementation margin position on the amount of undetected cemen...

References : Comparison of access-hole filling mat...

Millen C, Brägger U, Wittneben JG. Influence of prosthesis type and retention mechanism on complications with fixed implant-supported prostheses: a systematic review applying multivariate analyses. Int J Oral Maxillofac Implants. 2015;30(1):110–24. Guichet DL, Caputo AA, Choi H, Sorensen JA. Passivity of fit and marginal opening in screw- or cement-retained implant fixed partial denture desig...

Conclusions : Comparison of access-hole filling ma...

Within the limitation of the study, it was concluded that: The null-hypothesis “superficial and marginal deterioration of M4M and CR would not be significantly different” was accepted. The M4M (modified 4-META/MMA-TBB resin) and CR (composite resin) combined with a ceramic primer showed comparable characteristics (marginal integrity and wear behavior) in an access hole filling. The esthetic...

Discussion : Comparison of access-hole filling mat...

The analysis for the ratio of access-hole with or without marginal staining at the time of T = 12 M showed that the results in group CR (12/16) and in group M4M (12/16) were the same. For this reason, the marginal discrepancy pattern, different in both groups did not influence the aesthetical result. The occlusal contact point (A, B, or C) was compared to the marginal staining rate. Among the...

Discussion : Comparison of access-hole filling mat...

Focusing on numbers of access-hole showing a disappearance of the overfilling in an early period (up to T = 3 M), groups CR and M4M exhibited 82% (23/28) and 39.3% (11/28), respectively (Table 4). This can be explained by the differences of mechanical properties of both materials. The elastic moduli of M4M and CR are 1.9 and 7.9 MPa, respectively. Flexural strength of M4M is 66 MPa which i...

Discussion : Comparison of access-hole filling mat...

The in vivo evaluation is quite different from that of the in vitro analysis. In the previous study, all the specimens were calibrated to a flat surface with 2.5 mm diameter. In present study, each access hole had a different dimension and configuration. The filling surfaces were often ø3 to 4 mm in diameter. Access-holes located in the occlusal groove area or in the inclined cusp surface induc...

Discussion : Comparison of access-hole filling mat...

Nowadays, implant screw-retained prosthesis becomes a popular mode of implant supra-structure restoration. Cement retained implant restoration has issues including irretrievability and difficulty of controlling the cement excess beyond the abutment joint. The cement excess can be a major cause of peri-implantitis [13,14,15]. Screw-retained implant restoration has also some disadvantages including ...

Results : Comparison of access-hole filling materi...

Among the 56 access holes, no filling was dislodged during 12 months, and no complaint was registered from the patients regarding functional and aesthetical aspects. The results for surface areas changes of access-hole fillings at respective intervals were summarized in Table 3 and Fig. 6. The mean values of the change from T = 1 M to T = 12 M were 77.1 ± 13.1% for group M4M and...

Methods : Comparison of access-hole filling materi...

The marginal depth of the access-hole filling at T = 0, T = 1 M, T = 3 M, and T = 6 M could not be defined successfully because of the overfilling phenomenon which disrupted the measurement of marginal gap depth and angle (Fig. 3a–e). Only the marginal depth and angle at T = 12 M could be measured with the same digital microscope, and the mean value for each group was ca...

Methods : Comparison of access-hole filling materi...

Patients who received a metal framed ceramic screw retained implant crown or bridge were included in this study. These access holes were delimited only by ceramic. Those with metal surface exposure were excluded from this study. Patients with edentulous arch or section, full or partial denture as antagonists were excluded from the study. During the evaluation period, 2 patients (male) dropped out ...

Methods : Comparison of access-hole filling materi...

A total of 60 access-holes in 14 patients (5 male and 9 female) aging from 34 to 69 were restored and observed during 12 months. All subjects were informed about the study, and their written consent to participate in the study was taken. The materials used in this study are presented in Table 1. They include a phosphoric acid monomer ceramic primer (CP): UCP (Super-Bond Universal Ceramic Primer...

Background : Comparison of access-hole filling mat...

The retention of implant-supported prostheses is provided by the use of a screw or cement. Recently, it was demonstrated that cement-retained prostheses had a higher rate of technical and biological complications [1], despite a better passive fit than the screw-retained restorations [2]. The CAD/CAM development of the implant-supported prostheses allows a better passively fit with screw-retained p...

Abstract : Comparison of access-hole filling mater...

Screw retained implant prostheses seem to be an efficient restorative method to prevent peri-implantitis caused by cement excess around the abutment. The drawback of the screw-retained prostheses is the difficulty to realize an efficient access-hole filling functionally and aesthetically. Up to now, few in vitro and in vivo studies were reported in the literature. The aim of this study was to eval...

Fig. 5. Survival rate of dental implants after aut...

Fig. 5. Survival rate of dental implants after autologous bone augmentation Fig. 5. Survival rate of dental implants after autologous bone augmentation

Fig. 4. Postoperative nerve alterations. Single as...

Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Double asterisk, N refers to the total number of the surgical approaches in the maxilla (N = 225) Fig. 4. Postoperative nerve alterations. Single asterisk, N refers to the total number of the surgical approaches in the mandible (N = 155). Dou...

Fig. 3. Surgical outcome after autologous augmenta...

Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites Fig. 3. Surgical outcome after autologous augmentation procedures from different donor sites

Fig. 2. Survival rate of autologous bone grafts : ...

Fig. 2. Survival rate of autologous bone grafts Fig. 2. Survival rate of autologous bone grafts

Fig. 1. Postoperative complications at the donor a...

Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378) Fig. 1. Postoperative complications at the donor and recipient site, N refers to the total number of the donor sites (N = 300), N refers to the total number of the recipient sites (N = 378)

Table 3 Intra- and postoperative complications aft...

Postoperative complications %/procedures (N) At donor sitea    Wound infection 2.6% (8/300) At recipient site...

Table 2 Donor sites and numbers of bone grafts as ...

Donor site Bone grafts (N)/patients (N) Lateral zygomatic buttress 113/112 Mandibular ramus (retromolar) ...

Table 1 Patient characteristics at the time of aug...

Patient characteristics N (%) Gendera    Male 250 (89.6%)  Female 29 (10.4%) ...

About this article : Autogenous bone grafts in ora...

Sakkas, A., Wilde, F., Heufelder, M. et al. Autogenous bone grafts in oral implantology—is it still a “gold standard”? A consecutive review of 279 patients with 456 clinical procedures. Int J Implant Dent 3, 23 (2017). https://doi.org/10.1186/s40729-017-0084-4 Download citation Received: 27 February 2017 Accepted: 22 May 2017 Published: 01 June 2017 DOI: https://doi...

Rights and permissions : Autogenous bone grafts in...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Author information : Autogenous bone grafts in ora...

Department of Oral and Plastic Maxillofacial Surgery, Military Hospital Ulm, Academic Hospital of the University of Ulm, Oberer Eselsberg 40, 89081, Ulm, Germany Andreas Sakkas, Frank Wilde, Marcus Heufelder & Alexander Schramm Institute of Anatomy, Medical Faculty of Leipzig University, Leipzig, Germany Karsten Winter Department of Oral and Plastic Maxillofacial Surgery, University Hospit...

Acknowledgements : Autogenous bone grafts in oral ...

The authors thank the patients for their kindness to participate as study cases and the whole medical team at the Bundeswehrkrankenhaus Ulm. AS participated in its design and coordination, carried out the data selection, and drafted the manuscript, and is the corresponding author. FW participated in its design and coordination and helped in drafting the manuscript. MH participated in its design a...

References : Autogenous bone grafts in oral implan...

Semper W, Kraft S, Mehrhof J, Nelson K. Impact of abutment rotation and angulation on marginal fit: theoretical considerations. Int J Oral Maxillofac Implants. 2010;25:752–8. Wiltfang J, Jätschmann N, Hedderich J, Neukam FW, Schlegel KA, Gierloff M. Effect of deproteinized bovine bone matrix coverage on the resorption of iliac cortico-spongeous bone grafts—a prospective study of two cohorts....

References : Autogenous bone grafts in oral implan...

Chiapasco M, Zaniboni M. Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations: a systematic review. Clin Oral Implants Res. 2009;20:113–23. Felice P, Pellegrino G, Checchi L, Pistilli R, Esposito M. Vertical augmentation with interpositional blocks of anorganic bovine bone vs. 7-mm-long implants in posterior mandibles: 1-year results of a randomized clinical...

References : Autogenous bone grafts in oral implan...

Verdugo F, Castillo A, Moragues MD, Pontón J. Bone microbial contamination influences autogenous grafting in sinus augmentation. J Periodontol. 2009;80:1355–64. Wiltfang J, Schultze-Mosgau S, Merten HA, Kessler P, Ludwig A, Engelke W. Endoscopic and ultrasonographic evaluation of the maxillary sinus after combined sinus floor augmentation and implant insertion. Oral Surg Oral Med Oral Pathol O...

References : Autogenous bone grafts in oral implan...

von Arx T, Buser D. Horizontal ridge augmentation using autogenous block grafts and the guided bone regeneration technique with collagen membranes: a clinical study with 42 patients. Clin Oral Implants Res. 2006;17:359–66. Levin L, Nitzan D, Schwartz-Arad D. Success of dental implants placed in intraoral block bone grafts. J Periodontol. 2007;78:18–21. Andersson L. Patient self-evaluation of...

References : Autogenous bone grafts in oral implan...

Aghaloo TL, Moy PK. Which hard tissue augmentation techniques are the most successful in furnishing bony support for implant placement? Int J Oral Maxillofac Implants. 2007;22:49–70. Margonar R, dos Santos PL, Queiroz TP, Marcantonio E. Rehabilitation of atrophic maxilla using the combination of autogenous and allogeneic bone grafts followed by protocol-type prosthesis. J Craniofac Surg. 2010;2...

References : Autogenous bone grafts in oral implan...

Schwartz-Arad D, Dori S. Intraoral autogenous onlay block bone grafting for implant dentistry. Refuat Hapeh Vehashinayim. 2002;19:35–9. 77. Misch CM. Ridge augmentation using mandibular ramus bone grafts for the placement of dental implants: presentation of a technique. Pract Periodontics Aesthet Dent. 1996;8:127–35. Altiparmak N, Soydan SS, Uckan S. The effect of conventional surgery and pi...

References : Autogenous bone grafts in oral implan...

Jensen AT, Jensen SS, Worsaae N. Complications related to bone augmentation procedures of localized defects in the alveolar ridge. A retrospective clinical study. Oral Maxillofac Surg. 2016;20(2):115–22 [Epub ahead of print]. Buser D, Dula K, Hirt HP, Schenk RK. Lateral ridge augmentation using autografts and barrier membranes: clinical study with 40 partially edentulous patients. J Oral Maxill...

Conclusions : Autogenous bone grafts in oral impla...

The results of the clinical study proves the reliability and low comorbidity of autologous bone grafts in preprosthetic alveolar ridge reconstructions prior to implant insertion. The high graft success rate (95.6%) and the low early implant failure rate (0.38%) in a surveillance of all patients treated in three following years with this technique showing no exclusion and no dropout of any case for...

Discussion : Autogenous bone grafts in oral implan...

Data on risk factors based on the original examination and documentation are difficult to assess the adverse effects of variable factors on the surgical prognosis because of the multifactorial genesis of surgical complications [73]. Factors such as gender, age, or smoking habit could be associated with postoperative complications after two-stage dentoalveolar reconstruction with autologous bone gr...

Discussion : Autogenous bone grafts in oral implan...

The results of the present study have to take into account the absence of a control group with patients undergoing bone augmentation procedures with bone substitutes (allogen, alloplastic, exogen). Without a comparative group of grafting surgeries using alternative bone material, only limited statements can be made. However, the excellent surgical outcome of autologous surgical methods providing ...

Discussion : Autogenous bone grafts in oral implan...

The use of autologous bone in this study has shown excellent graft survival and success rate (95.6%). This is equal to the results from the studies on implants inserted in reconstructed sites [6, 8, 24]. The early implant survival rate of 99.7% found in the present material is very high comparable to that in the previous systematic reviews after staged horizontal ridge augmentation [9, 10, 22, 62,...

Discussion : Autogenous bone grafts in oral implan...

Of the sinus floor elevations performed in this study, 84.8% were defined absolutely successful. Only two of our 72 patients having sinus lift operations could not finally be treated with dental implants. These results are comparable to other studies considering the sinus graft to be a safe treatment modality with few complications [6, 8, 51,52,53]. Raghoebar et al. reported incidences of sinus co...

Discussion : Autogenous bone grafts in oral implan...

Postoperative morbidity after mandibular bone harvesting procedures was reported to be mainly related to temporary or permanent neural disturbances involving the inferior alveolar nerve and its branches [19]. In this study, only the incidence of the temporary hypoesthesia of the mandibular and lingual nerve after harvesting from the retromolar area could be detected. It was 10.4 and 2.8%, respecti...

Discussion : Autogenous bone grafts in oral implan...

Systematic reviews have failed to find evidence that one particular grafting technique is superior to others [10]. Intraoral bone grafts from the mandibular symphysis, mandibular ramus, and maxillary tuberosity provide a good treatment modality for ridge augmentation, and the amount of bone available for harvesting is sufficient for defects up to the width of three teeth [42]. Harvesting of retrom...

Discussion : Autogenous bone grafts in oral implan...

Several grafting procedures have been described to create sufficient volume of bone for implant placement [8, 9]. Autologous bone grafts can be harvested by an intraoral approach (mandibular ramus, mandibular symphysis, zygomatic buttress) or from distant sites (iliac crest, calvaria, and etc.) [17, 36, 37]. However, bone harvesting potentially causes donor site morbidity which is a major issue fo...

Results : Autogenous bone grafts in oral implantol...

The surgical outcome after augmentation and implantation procedures is presented in Fig. 5.

Results : Autogenous bone grafts in oral implantol...

The average healing period until implant placement after bone harvesting was 4.53 months. Initially, 546 implants in 279 patients were planned. After the healing period, it was possible to place 525 implants in 436 successfully augmented areas in 259 patients. Three hundred implants were inserted in the maxilla and 225 in the mandible. The remaining 21 implants planned for 20 patients could not b...

Results : Autogenous bone grafts in oral implantol...

Regarding intraoperative complications, all sinus membrane perforations were covered with a resorbable collagen membrane (Bio-Gide®, Geistlich Biomaterials, Baden-Baden, Germany) which applied as sealant to overlap the site of perforation prior to insertion of the graft material. These patients were advised to avoid physical stress, blowing their noses, or sneezing for a period of 3 weeks, and n...

Results : Autogenous bone grafts in oral implantol...

No permanent damage to any trigeminal nerves was evident in any of our entire cohort. All cases of postoperative hypoesthesia of the mental, lingual, or infraorbital nerve were just a temporary nature. At the time of implant surgery, none of these patients reported any persisting neural disturbances (Fig. 4). In eleven patients, hypoesthesia of the mental area was mentioned, and three of them al...

Results : Autogenous bone grafts in oral implantol...

Thirty-eight patients underwent a total of 116 augmentation procedures harvesting from the iliac crest. In 20 patients, a bone graft augmentation of the maxilla and the mandible in combination with bilateral sinus floor augmentations was performed. Eighteen patients had augmentations only in the maxilla, involving bone grafting and sinus lift elevations. Totally, 76 sinus lifts with bone material ...

Results : Autogenous bone grafts in oral implantol...

A total of 104 retromolar bone graft procedures in 86 patients were conducted. Twenty-two harvesting procedures were performed for augmentation of the maxilla and 82 for the mandible. Seven retromolar bone grafts (93.2%) in seven single-tooth gap dental regions by seven patients had been lost. Therefore, seven implants could not be inserted in augmented alveolar sites after graft failure. Three of...

Results : Autogenous bone grafts in oral implantol...

In six patients, a partial graft resorption was detected at the time of implantation and an additional simultaneous augmentation with bone chips harvested with the Safescraper device (C.G.M. S.p.A., Divisione Medicale META, Italy) was then necessary in order to ensure the osseointegration of the implants. Two out of these six cases had grafts from the crista zygomatico-alveolaris, two from the ram...

Results : Autogenous bone grafts in oral implantol...

A total of 112 sinus floor elevations were performed. In all of the cases, implants were inserted in a two-stage procedure. The donor site for harvesting the bone for the sinus elevations was in 76 procedures in the iliac crest area, and in 36 procedures, the bone was harvested with a bone scraper device from the lateral sinus wall at the site of sinus lifting. The distribution and number of tran...

Results : Autogenous bone grafts in oral implantol...

Two hundred seventy-nine patients—250 men and 29 women—underwent 456 augmentation procedures involving autologous bone grafts prior to implant placement. The patients ranged in age from 18.5 to 71.5 years (average 43.1 years) at the moment of augmentation surgery. Of those patients, 162 (58.1%) were younger than 40 years of age and 117 (41.9%) were older than 40 years of age. Caries or pe...

Methods : Autogenous bone grafts in oral implantol...

Early and late implant loss was documented in this study, defining the clinical success of osseointegration. Early implant failures were assessed before the acquisition of osseointegration, i.e., before the placement of prosthodontic restorations. Early implant failure could occur from the time of placement, during the healing phase and before abutment connection. The implant inserted after re-aug...

Methods : Autogenous bone grafts in oral implantol...

Medical history of patient Age of patient at the time of bone harvesting and augmentation History of periodontal disease Smoking habits Donor site Jaw area and dental situation of the recipient site Intraoperative complications Postoperative complications after augmentation Management of complications Bone graft stability and clinical resorption prior to implant placement Complications a...

Methods : Autogenous bone grafts in oral implantol...

In addition to the bone already gained with the bone scraper device from the sinus wall during the antrostomy, bone was harvested with the same device from the maxillary buccal buttress, if more volume was needed. By taking this approach, the collection of enough bone for the augmentation of at least two implantation sites was feasible with a mean surgical time of 5 to 10 min for harvesting. In c...

Methods : Autogenous bone grafts in oral implantol...

Grafting from the iliac crest was always performed under general anesthesia in a two-team approach. The iliac crest was exposed and autogenous grafts from the anterosuperior inner edge of the iliac wing were harvested with an oscillating saw and/or a chisel, keeping a safe distance of around 2 cm from the anterosuperior iliac spine. After harvesting the bone grafts, the corticocancellous bone blo...

Methods : Autogenous bone grafts in oral implantol...

A standardized two-stage surgical protocol was used, and all sites were treated in a similar fashion. In the first intervention, a bone block harvested from the donor site was fixed with osteosynthesis titanium screws to the recipient site as an onlay graft to achieve a horizontal and/or vertical enlargement of the alveolar ridge. Placement of the bone graft was always guided by an augmentation te...

Methods : Autogenous bone grafts in oral implantol...

For this retrospective cohort study, we reviewed the records of all patients without exclusion criteria who were referred to the department of oral and plastic maxillofacial surgery at the military hospital of Ulm, Germany, between January 2009 and December 2011 for alveolar ridge augmentations prior to implant insertions using autologous bone grafts harvested from different donor sites and unilat...

Background : Autogenous bone grafts in oral implan...

In our military outpatient center exclusively, autologous bone transplantations harvested from different donor sites were used intraorally (crista zygomatico-alveolaris, ramus mandible, symphysis mandible, anterior sinus wall) and extraorally (iliac crest) to reconstruct severe horizontal and/or vertical alveolar ridge atrophy prior to implant placement. The aim of this study was to assess the cli...

Background : Autogenous bone grafts in oral implan...

Although the iliac crest is most often used in jaw reconstruction, a significant bone resorption has been mentioned [12]. This disadvantage, and the fact that dental implants do not always require a large amount of bone, has increased the use of autologous block bone grafts from intraoral sources [13]. Bone grafts from intraoral donor sites offer several benefits like surgical accessibility, proxi...

Background : Autogenous bone grafts in oral implan...

Oral implantation has a significant role in the rehabilitation of patients. Bone reconstruction techniques have been advanced in order to optimize the esthetic and functional outcome. However, the restoration of the oral function of atrophic alveolar crests still remains a challenge in oral implantology. Bone augmentation procedures are often indicated to allow implant placement in an optimal thre...

Abstract : Autogenous bone grafts in oral implanto...

This review demonstrates the predictability of autologous bone material in alveolar ridge reconstructions prior to implant insertion, independent from donor and recipient site including even autologous bone chips for sinus elevation. Due to the low harvesting morbidity of autologous bone grafts, the clinical results of our study indicate that autologous bone grafts still remain the “gold standar...

Abstract : Autogenous bone grafts in oral implanto...

This study assessed the clinical outcomes of graft success rate and early implant survival rate after preprosthetic alveolar ridge reconstruction with autologous bone grafts. A consecutive retrospective study was conducted on all patients who were treated at the military outpatient clinic of the Department of Oral and Plastic Maxillofacial Surgery at the military hospital in Ulm (Germany) in the ...

Fig. 8. Soft tissue dehiscence (a) CCXBB exposure ...

Fig. 8. Soft tissue dehiscence (a) CCXBB exposure 15 weeks after bone augmentation, the dehiscence healed 2 weeks later after reducing the graft exposure (b) after soft tissue augmentation and abutment connection leading to the loss of the mesial implant. After partial removal of the bone graft and place a connective tissue graft the area healed properly and a month later it was possible to re...

Fig. 7. Second stage surgery of patient in Fig. 1...

Fig. 7. Second stage surgery of patient in Fig. 1. a Vestibular depth reduction after augmentation and implant placement. b Partial thickness and apical repositioned flap. c CMX healing and soft tissue dehiscence with CCXBB exposure. d Dehiscence healing after re-contouring and buccal emergency profile. e Buccal aspect of the final restoration. f Buccal ridge contour Fig. 7. Second stage sur...

Fig. 6. Immunohistochemical analysis of slices fro...

Fig. 6. Immunohistochemical analysis of slices from the same sample with four different markers. a TRAP. b OPN. c ALP. d OSC Fig. 6. Immunohistochemical analysis of slices from the same sample with four different markers. a TRAP. b OPN. c ALP. d OSC

Fig. 5. Histomorphometric analysis of the same sam...

section stained with Levai-Laczkó. b Tissue identification of the ROI. c Closer view aized bone and CCXBB. d Closer view of b Fig. 5. Histomorphometric analysis of the same sample. a Ground section stained with Levai-Laczkó. b Tissue identification of the ROI. c Closer view a arrow pointing a cement line between new mineralized bone and CCXBB. d Closer view of b

Fig. 4. Histological samples. a CCXBB control with...

Fig. 4. Histological samples. a CCXBB control without implantation. b Histologic samples with acute inflammatory infiltration. c Histologic sample with limited remaining CCXBB and large bone ingrowth Fig. 4. Histological samples. a CCXBB control without implantation. b Histologic samples with acute inflammatory infiltration. c Histologic sample with limited remaining CCXBB and large bone ingr...

Fig. 3. Re-entry procedure of patient in Fig. 1. ...

Fig. 3. Re-entry procedure of patient in Fig. 1. a Buccal aspect of the augmented region. b Horizontal bone augmentation. c Screws and pins removal and bone trephine sampling. d Implants placement and buccal bone width from the implant shoulder. e Primary flap closure. f Implants submerged healing Fig. 3. Re-entry procedure of patient in Fig. 1. a Buccal aspect of the augmented region. b Ho...

Fig. 2. Lateral bone augmentation of the alveolar ...

Fig. 2. Lateral bone augmentation of the alveolar crest (a) atrophic ridge. b Perforations and adaptation of the cortical layer. c Shaping, pre-wetting and fixation of CCXBB with titanium screws. d Horizontal contour and peripheral gap between CCXBB and bone layer. e Outlying DBBM filling. f CM stabilized with pins Fig. 2. Lateral bone augmentation of the alveolar crest (a) atrophic ridge. b ...

Fig. 1. Study chart and follow-up visits : Histomo...

Fig. 1. Study chart and follow-up visits Fig. 1. Study chart and follow-up visits

Table 4 Implant loss and tissue characteristics : ...

Differentiated tissues Implant lost (Yes/no) Mean SD Percentage SD (%) ...

Table 3 Immunohistochemical markers proportions (i...

Patient TRAP (%) OPN (%) ALP (%) OSC (%) 1 ...

Table 2 Quantitative histological analysis : Histo...

Tissue type Mean Standard deviation Median CI 95% Mineralized bone ...

Table 1 Clinical and histomorphometry assessments ...

Patient Soft tissue dehiscence Mineralized bone (%) CCXBB (%) Bone marrow (%) Connect...

About this article : Histomorphometric and immunoh...

Ortiz-Vigón, A., Martinez-Villa, S., Suarez, I. et al. Histomorphometric and immunohistochemical evaluation of collagen containing xenogeneic bone blocks used for lateral bone augmentation in staged implant placement. Int J Implant Dent 3, 24 (2017). https://doi.org/10.1186/s40729-017-0087-1 Download citation Received: 21 March 2017 Accepted: 12 June 2017 Published: 21 Ju...

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Author information : Histomorphometric and immunoh...

ETEP Research Group, Facultad de Odontología, Universidad Complutense de Madrid, Plaza Ramón y Cajal, 28040, Madrid, Spain Alberto Ortiz-Vigón, Sergio Martinez-Villa, Iñaki Suarez, Fabio Vignoletti & Mariano Sanz You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar ...

Acknowledgements : Histomorphometric and immunohis...

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Acknowledgements : Histomorphometric and immunohis...

We wish to acknowledge the dedication and scientific advise of Prof. Dr. Tord Berglundh on the histological analysis as well as the diligent work in processing the histological samples to Estela Maldonado for the immunohistochemistry and Asal Shikhan and Fernando Muñoz for the histomorphometry. The work of Esperanza Gross on the statistical analysis is highly acknowledged. This study was partial...

References : Histomorphometric and immunohistochem...

Patti A, Gennari L, Merlotti D, Dotta F, Nuti R. Endocrine actions of osteocalcin. Int J Endocrinol. 2013;2013:846480. Schwarz F, Herten M, Sager M, Wieland M, Dard M, Becker J. Histological and immunohistochemical analysis of initial and early osseous integration at chemically modified and conventional SLA titanium implants: preliminary results of a pilot study in dogs. Clin Oral Implants Res. 2...

References : Histomorphometric and immunohistochem...

Araujo MG, Linder E, Lindhe J. Bio-Oss collagen in the buccal gap at immediate implants: a 6-month study in the dog. Clin Oral Implants Res. 2011;22:1–8. Chiapasco M, Colletti G, Coggiola A, Di Martino G, Anello T, Romeo E. Clinical outcome of the use of fresh frozen allogeneic bone grafts for the reconstruction of severely resorbed alveolar ridges: preliminary results of a prospective study. I...

References : Histomorphometric and immunohistochem...

Jeno L, Geza L. A simple differential staining method for semi-thin sections of ossifying cartilage and bone tissues embedded in epoxy resin. Mikroskopie. 1975;31:1–4. Dias RR, Sehn FP, de Santana Santos T, Silva ER, Chaushu G, Xavier SP. Corticocancellous fresh-frozen allograft bone blocks for augmenting atrophied posterior mandibles in humans. Clin Oral Implants Res. 2016;27:39–46. Nissan ...

References : Histomorphometric and immunohistochem...

Cremonini CC, Dumas M, Pannuti C, Lima LA, Cavalcanti MG. Assessment of the availability of bone volume for grafting in the donor retromolar region using computed tomography: a pilot study. Int J Oral Maxillofac Implants. 2010;25:374–8. Nkenke E, Weisbach V, Winckler E, Kessler P, Schultze-Mosgau S, Wiltfang J, et al. Morbidity of harvesting of bone grafts from the iliac crest for preprosthetic...

References : Histomorphometric and immunohistochem...

Sanz M, Vignoletti F. Key aspects on the use of bone substitutes for bone regeneration of edentulous ridges. Dent Mater. 2015;31:640–7. Benic GI, Hammerle CH. Horizontal bone augmentation by means of guided bone regeneration. Periodontology. 2014;66:13–40. Beretta M, Cicciu M, Poli PP, Rancitelli D, Bassi G, Grossi GB, et al. A Retrospective Evaluation of 192 Implants Placed in Augmented Bon...

Abbreviations : Histomorphometric and immunohistoc...

Alkaline phosphatase Cone beam computed tomography Collagen containing xenogeneic bone block Native collagen membrane Deproteinized bovine bone mineral Etiology and Therapy of Periodontal Diseases Osteopontin Osteocalcine Tartrate-resistant acid phosphatase

Conclusions : Histomorphometric and immunohistoche...

Within the limitations of this clinical study, we may conclude that the use of CCXBB in combination with DBBM particles and a native bilayer collagen membrane for staged lateral bone augmentation in severe atrophic alveolar crests achieved significant horizontal crestal width allowing for staged implant placement in most of the patients. Histological analysis and implant survival records indicate ...

Discussion : Histomorphometric and immunohistochem...

The immune-histochemical results reported expression of osteopontin mainly at the border between mineralized vital bone (MVB) with CCXBB, what coincides with findings from previous reports [38,39,40]. Alkaline phosphatase (ALP) is considered as an early osteoblast differentiation marker [41]. ALP-positive cells were detectable, in all specimens on the periphery of MVB, associated to areas of new b...

Discussion : Histomorphometric and immunohistochem...

When correlating the clinical results and the histological outcomes, there was a positive association between the presence of soft tissue dehiscence with CCXBB exposure and a diminished amount of new mineralized bone (p = 0.06). This lower amount of new bone within the xenogeneic graft suggests a lack of full graft integration and diminished vascular supply, what may have caused the soft tissu...

Discussion : Histomorphometric and immunohistochem...

The purpose of this investigation was to evaluate histologically and immunohistochemically the behavior of CCXBB blocks when used for staged lateral bone augmentation in severe human horizontal residual bone defects. Six months after the regenerative intervention using the CCXBB blocks, the mean increase in bone width was 4.12 mm and hence, this outcome allowed for the placement of dental implant...

Results : Histomorphometric and immunohistochemica...

The results from the histomorphometric measurements are depicted in Table 2. Bone biopsies were composed by 21.37% (SD 7.36) of residual CCXBB, 26.90% (SD 12.21) of mineralized vital bone (MVB), 47.13% (SD 19.15) of non-mineralized tissue and 0.92% of DBBM (Fig. 5b). Biopsies from patients who lost their implants had a statistical significant lower amount of MVB (p = 0.01u) and a statistical...

Results : Histomorphometric and immunohistochemica...

Twenty-eight CCXBB blocks were placed in 15 patients that fulfilled the selection criteria (12 women and 3 men) with a mean age of 54.5 (SD 8.34). The detailed clinical and radiographical outcomes have been reported previously [21]. In brief, one patient experienced pain and soft tissue dehiscence leading to removal of the graft material 3 days after the regenerative procedure. Another patient r...

Methods : Histomorphometric and immunohistochemica...

For the immunohistochemical analysis, the semi-thin sections were incubated over night with primary antibodies at 4 °C (Santa Cruz Biotechnology Inc., Santa Cruz, Calif., USA). The antibody dilutions used were alkaline phosphatase (ALP) 1:100, osteopontin (OPN) 1:100, osteocalcin (OSC) 1:100, and tatrate resistant acid phosphatase (TRAP) 1:100. The obtained semi-thin sections were evaluated wit...

Methods : Histomorphometric and immunohistochemica...

Twenty-six weeks after the regenerative procedure the patient returned for the re-entry intervention for placement of dental implants. After raising full-thickness flaps, the augmented area was exposed and horizontal crestal width measurements were performed. Then, the surgeon evaluated the bone availability and if implant placement was considered possible, a core bone biopsy was harvested with th...

Methods : Histomorphometric and immunohistochemica...

CCXBB (Bio-Graft® Geistlich Pharma) is a bone substitute material in a natural block form. The dimensions of the Bio-Graft block are 10 mm in height, 10 mm in length and 5 mm in width. It consists of a natural cancellous bone structure of hydroxyapatite and endogenous collagen type I and III, equine origin and is a class III medical device according to the Medical Device Directive 93/42 EECs...

Methods : Histomorphometric and immunohistochemica...

The present manuscript reports the histological outcomes of a prospective single arm study evaluating the safety and clinical performance of CCXBB blocks when used as replacement bone grafts for lateral bone augmentation prior to staged implant placement. The results of the clinical and radiographic outcomes have been reported in a previous publication [21]. For correlation of the histological wit...

Background : Histomorphometric and immunohistochem...

Different techniques and grafting materials have been used for the horizontal reconstruction of deficient alveolar processes before implant placement, resulting in different degrees of predictability and clinical outcomes [1]. Among the grafting materials, particulated xenogeneic materials have been extensively studied in both experimental and clinical studies and when combined with porcine-derive...

Abstract : Histomorphometric and immunohistochemic...

The osteoconductive properties of collagen containing xenogeneic bone blocks (CCXBB) remain unclear. The aim of this prospective single-arm clinical study was to assess the histological outcomes of CCXBB blocks used as bone replacement grafts for lateral bone augmentation procedures. In 15 patients with severe horizontal alveolar ridge resorption, lateral augmentation procedures were performed us...

Fig. 3. Forest plot of quality of life. A statisti...

Fig. 3. Forest plot of quality of life. A statistically significant improvement was observed in the quality of life parameter with mini implants than standard implants Fig. 3. Forest plot of quality of life. A statistically significant improvement was observed in the quality of life parameter with mini implants than standard implants

Fig. 2. Risk of bias of the included studies : Com...

Fig. 2. Risk of bias of the included studies Fig. 2. Risk of bias of the included studies

Fig. 1. PRISMA flow diagram : Comparison of patien...

Fig. 1. PRISMA flow diagram Fig. 1. PRISMA flow diagram

Table 2 Grading the strength of evidence : Compari...

Comparison of parameters between standard and mini-implants for implant-supported overdenture: Outcomes Parameter values No. of participants (studies) ...

Table 1 List of included studies : Comparison of p...

Author Participant Intervention Comparator Outcome De Souza 2015[8] ...

About this article : Comparison of patient satisfa...

Sivaramakrishnan, G., Sridharan, K. Comparison of patient satisfaction with mini-implant versus standard diameter implant overdentures: a systematic review and meta-analysis of randomized controlled trials. Int J Implant Dent 3, 29 (2017). https://doi.org/10.1186/s40729-017-0092-4 Download citation Received: 12 April 2017 Accepted: 22 June 2017 Published: 01 July 2017 DOI...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Comparison of patient satisf...

Gowri Sivaramakrishnan and Kannan Sridharan declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Comparison of patient satisfa...

Department of Oral Health, College of Medicine, Nursing and Health Sciences, Fiji National University, Brown Street, Suva, Fiji Gowri Sivaramakrishnan Department of Pharmacology, Fiji National University, Extension Street, Suva, Fiji Kannan Sridharan You can also search for this author in PubMed Google Scholar You can also search for this author in ...

Acknowledgements : Comparison of patient satisfact...

We acknowledge Cochrane reviews for utilizing RevMan software for generating the pooled results and Forest plots. No source of funding.

References : Comparison of patient satisfaction wi...

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References : Comparison of patient satisfaction wi...

Kumari P, Verma M, Sainia V, Gupta A, Gupta R, Gill S. Mini-implants, mega solutions: a case series. J Prosthodont. 2015. doi:10.1111/jopr.12382. Jackson BJ. Fixed partial denture treatment with mini dental implants. J Oral Implantol. 2014;40:744–50. Flanagan D, Mascolo A. The mini dental implant in fixed and removable prosthetics: a review. J Oral Implantol. 2011;37 Spec No:123–32. doi:10.1...

Conclusion : Comparison of patient satisfaction wi...

However, considering the results obtained from available evidence, mini-implants tend to provide good patient satisfaction compared to standard diameter implants when used for implant-supported overdentures. The results of this meta-analysis should be interpreted keeping in the mind the limited availability of data to be included. This paper would serve as a basis for future research comparing min...

Discussion : Comparison of patient satisfaction wi...

This study is an attempt to identify patient satisfaction with mini-implant overdentures compared to standard diameter implant-supported overdentures in completely edentulous patients. Implant-supported overdentures have been reported to offer many advantages like decreased bone resorption, reduced prosthesis movement, better esthetics, better occlusion and tooth positioning, improved occlusal loa...

Results : Comparison of patient satisfaction with ...

A total of 183 articles were identified using the search strategy. Screening of these papers yielded four studies comparing mini-implant-retained overdentures and standard diameter implant overdentures and were found eligible to be included in the systematic review [8,9,10,11]. Two studies [8, 11] comparing patient satisfaction between the groups were included for the meta-analysis. The PRISMA flo...

Materials and methodology : Comparison of patient ...

The protocol for this review was registered with International prospective register of systematic reviews (PROSPERO) with the registration number CRD42016043075. The review protocol can be accessed at https://www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42016043075. A through literature search was conducted and was completed on 9 July 2016. The primary database used was MEDLINE (via PubMed...

Review : Comparison of patient satisfaction with m...

Implants have been considered to improve treatment outcomes of completely edentulous patients with anatomical challenges compromising the retention and stability. The root form dental implants which are 3–5 mm in diameter are considered standard diameter implants while less than 3 mm diameter implants are termed mini-implants [1]. Initially, mini-implants were used as a temporary measure, with...

Abstract : Comparison of patient satisfaction with...

Mini-implants have certain advantages over standard size implants which are being tested in various randomized controlled trials. This systematic review and meta-analysis aims to compare conventional implant overdentures to mini-implant-retained overdentures as regards to patient satisfaction. Electronic databases were searched for eligible studies data required were extracted. The extracted data ...

Fig. 6. Loading of implant off-axially : Peri-impl...

Fig. 6. Loading of implant off-axially Fig. 6. Loading of implant off-axially

Fig. 5. Loading of implant axially : Peri-implant

Fig. 5. Loading of implant axially Fig. 5. Loading of implant axially

Fig. 4. Installation of strain gauges on surfaces ...

Fig. 4. Installation of strain gauges on surfaces of epoxy resin adjacent to mini implants Fig. 4. Installation of strain gauges on surfaces of epoxy resin adjacent to mini implants

Fig. 3. Lava Ultimate Restorative crown on the two...

Fig. 3. Lava Ultimate Restorative crown on the two mini implants. Fig. 3. Lava Ultimate Restorative crown on the two mini implants.

Fig. 2. Metal crown supported on two mini implants...

Fig. 2. Metal crown supported on two mini implants Fig. 2. Metal crown supported on two mini implants

Fig. 1. a Standard, b short-wide, and c single-pie...

Fig. 1. a Standard, b short-wide, and c single-piece mini implants

Table 5 Descriptive statistics and results of comp...

Crown Implant type Axial Off-axial P-value Mean SD ...

Table 4 Descriptive statistics and results of comp...

Axial Off-axial P value Mean SD Mean SD ...

Table 3 Descriptive statistics and results of comp...

Lava Ultimate crowns Metal crowns P value Mean SD Mean ...

Table 2 Descriptive statistics and results of comp...

Load Crown type Standard Short-wide Double mini P value ...

Table 1 Descriptive statistics and results of comp...

Standard Short-wide Double mini P value Mean SD Mean ...

About this article : Peri-implant biomechanical re...

Elfadaly, L.S., Khairallah, L.S. & Al Agroudy, M.A. Peri-implant biomechanical responses to standard, short-wide, and double mini implants replacing missing molar supporting hybrid ceramic or full-metal crowns under axial and off-axial loading: an in vitro study. Int J Implant Dent 3, 31 (2017). https://doi.org/10.1186/s40729-017-0094-2 Download citation Received: 14 Februar...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Peri-implant biomechanical r...

The authors L.S.Elfadaly, L.S.Kheirallah, and M.A.Alagroudy state that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Peri-implant biomechanical re...

Fixed Prosthodontics, Cairo University, Giza, Egypt Lamiaa Said Elfadaly, Lamiaa Sayed Khairallah & Mona Atteya Al Agroudy You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar LSE have...

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Gracis S, Nicholls J, Chalupnik J, Yuodelis R. Shock-absorbing behavior of five restorative materials used on implants. Int J Prosthodont. 1990;4:282–91. Skalak R. Biomechanical considerations in osseointegrated prostheses. J Prosthet Dent. 1983;49:843–8. Misch C. Clinical biomechanics in implant dentistry, Contemporary Implant Dentistry. 3rd ed. 2008. p. 543–56. mosby,inc. Lundgren D, La...

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Himmlova L, Dostalova T, Kacovsky A, Konvickova S. Influence of implant length and diameter on stress distribution: a finite element analysis. J Prosthet Dent. 2004;91(1):20–5. Shetty S, Puthukkat N, Bhat S, Shenoy K. Short implants: a new dimension in rehabilitation of atrophic maxilla and mandible. Journal of Interdisciplinary Dentistry. 2014;4(2):66. Misch C, Bidez M. Contemporary implant d...

References : Peri-implant biomechanical responses ...

Barbier L, Vander SJ, Krzesinski G, Schepers E, Van der Perre G. Finite element analysis of non-axial versus axial loading of oral implants in the mandible of the dog. J Oral Rehabil. 1998;25(11):847–58. Saime S, Murat C, Emine Y. The influence of functional forces on the biomechanics of implant-supported prostheses—a review. J Dent. 2002;30:271–82. Balshi T, Hernandez R, Pryszlak M, Range...

References : Peri-implant biomechanical responses ...

Mazor Z, Lorean A, Mijiritsky E, Levin L. Replacement of a molar with 2 narrow diameter dental implants. Implant Dent. 2012;21(1):36–8. Atwood D. Postextraction changes in the adult mandible as illustrated by micrographs of midsagittal sections and serial cephalometric roentgenograms. J Prosthet Dent. 1963;13:810–24. Felice P, Pellegrino G, Checchi L, Pistilli R, Esposito M. Vertical augment...

Conclusions : Peri-implant biomechanical responses...

Within the limitations of this in vitro study, the following conclusions could be drawn: Implant design, superstructure material, and load direction significantly affect peri-implant microstrains. The recorded compressive and tensile microstrains for the tested designs were within the physiologic loading range, as they did not exceed the compressive or tensile strength of the bone-implant interf...

Discussion : Peri-implant biomechanical responses ...

Regarding the effect of superstructure material on induced microstrains, generally, different implant designs supporting Lava Ultimate crowns showed higher mean microstrain values(1927.3 ± 1536.6 μɛ), in comparison with those supporting metal crowns (1313.7 ± 973.1 μɛ).Theoretical considerations [44, 45] and in vitro experiments [46,47,48,49] suggest that an occlusal material with ...

Discussion : Peri-implant biomechanical responses ...

Regarding the effect of direction of loading on induced microstrains, it was shown that changing the position of occlusal loading had a considerable effect on the amount of distribution of stresses where axial loading generated even distribution of load around the implant in comparison to off-axial loading where stresses were more pronounced in the area of load application. This might be due to th...

Discussion : Peri-implant biomechanical responses ...

Previous studies have shown that direct correlations exist between microstrain magnitudes and bone stability/instability conditions. This has been summarized by Frost, when bone is loaded below about 2000 microstrains, bone can easily repair what little microdamage occurs. Yet, when pathologic overloading occurs (over 4000 microstrains), stress and strain gradients exceed the physiologic tolerance...

Discussion : Peri-implant biomechanical responses ...

To replace a missing lower molar in compromised ridge, different treatment options were suggested, using either a standard size implant with surgical procedures, short-wide implant, or two mini implants. Concerning the use of mini implant, splinted multiple implants increase the surface area that interfaces with the bone to lessen the per square millimeters of force borne by the bone [11]. The imp...

Results : Peri-implant biomechanical responses to ...

Results revealed that standard implant showed the statistically significantly highest mean microstrain values (3362.4 ± 757.4 μɛ). Double mini implant showed statistically significantly lower mean microstrain values (801.6 ± 251.4 μɛ), while short-wide implant showed the statistically significantly lowest mean microstrain values (697.6 ± 79.7 μɛ), with a P value

Methods : Peri-implant biomechanical responses to ...

Data were presented as mean and standard deviation (SD) values. Data were explored for normality by checking data distribution and histograms, calculating mean and median values, and finally using Kolmogorov-Smirnov and Shapiro-Wilk tests of normality. Stress data showed non-parametric distribution, so the Kruskal-Wallis test was used to compare between the types of implants. The Mann-Whitney U te...

Methods : Peri-implant biomechanical responses to ...

Each crown was cemented to its corresponding implant-abutment assembly using temporary cement (Cavex Temporary Cement, Cavex, Holland). Each implant received 4 strain gauges (Kowa strain gages, Japan) placed on the mesial, distal, buccal, and lingual surfaces of the epoxy resin adjacent to the implants. At these selected sites, the thickness of the epoxy resin surrounding each implant was reduced...

Methods : Peri-implant biomechanical responses to ...

In the present study, the following materials were used: titanium root form endosseous implants of standard diameter and length (4-mm platform, 3.8-mm diameter,12-mm length, fixture bevel 0.2 mm, Super Line System, Dentium, USA), short-wide implant (7-mm platform, 5.8-mm diameter, 7-mm length, Super Line System, Dentium, Seoul, Korea) with 1.5-mm machined surface and 5.5-mm threaded surface that ...

Background : Peri-implant biomechanical responses ...

There are several factors that affect force magnitudes in peri-implant bone. The application of functional forces induces stresses and strains within the implant prosthesis complex and affect the bone remodeling process around implants [8, 9]. While there are several methods of measuring strain, the most common is with a strain gauge, a device whose electrical resistance varies in proportion to t...

Background : Peri-implant biomechanical responses ...

The molars are one of the first teeth to be lost over lifetime; thus, their replacement is frequently needed. Implantation is generally the preferred choice to replace a missing single tooth avoiding vital teeth preparation and bridge fabrication [1]. The mandibular bone loss occurs as knife-edge residual ridge where there is marked narrowing of the labiolingual diameter of the crest of the ridge...

Abstract : Peri-implant biomechanical responses to...

The aim of this study was to evaluate the biomechanical response of the peri-implant bone to standard, short-wide, and double mini implants replacing missing molar supporting either hybrid ceramic crowns (Lava Ultimate restorative) or full-metal crowns under two different loading conditions (axial and off-axial loading) using strain gauge analysis. Three single-molar implant designs, (1) single, ...

Fig. 7. Vestibular view of the final restoration :...

Fig. 7. Vestibular view of the final restoration Fig. 7. Vestibular view of the final restoration

Fig. 6. Occlusal view of the final restoration. In...

Fig. 6. Occlusal view of the final restoration. In this case, with the longest cantilever extension on a final restoration within this collective Fig. 6. Occlusal view of the final restoration. In this case, with the longest cantilever extension on a final restoration within this collective

Fig. 5. One-year post-surgery panoramic radiograph...

Fig. 5. One-year post-surgery panoramic radiograph with final restoration Fig. 5. One-year post-surgery panoramic radiograph with final restoration

Fig. 4. Occlusal view of implant-abutments 3 mont...

Fig. 4. Occlusal view of implant-abutments 3 months post-surgery at the first removal of the temporary restoration Fig. 4. Occlusal view of implant-abutments 3 months post-surgery at the first removal of the temporary restoration

Fig. 3. Fill-in of the occlusal perforations with ...

Fig. 3. Fill-in of the occlusal perforations with self-curing resin to connect the prostheses to the temporary titanium cylinders Fig. 3. Fill-in of the occlusal perforations with self-curing resin to connect the prostheses to the temporary titanium cylinders

Fig. 2. Preparation of the composite veneers for m...

Fig. 2. Preparation of the composite veneers for making the temporary restoration Fig. 2. Preparation of the composite veneers for making the temporary restoration

Fig. 1. Preparation of implant cavity through corr...

Fig. 1. Preparation of implant cavity through corresponding metal sleeves after extraction of the central incisors using a surgical template supported by hopeless remaining teeth Fig. 1. Preparation of implant cavity through corresponding metal sleeves after extraction of the central incisors using a surgical template supported by hopeless remaining teeth

Table 5 Marginal bone loss measured in mm : Six-im...

Collective Mesial Distal 1 year 55 months (40–84) 1 year ...

Table 4 Mean implant stability quotients (ISQ) of ...

Collective ISQ P At insertion 3 months Total (n = 57) 61.3 ± 7.8 ...

Table 3 Mean Periotest values (PT) of survived axi...

Collective PT value P At insertion 3 months Total (n = 57) −1.8 ± 2.4 ...

Table 2 Life table of implants : Six-implant-suppo...

Period # of implants # of failures Survival rate (%) Cumulative survival rate (%) 0 t...

Table 1 Diameters and lengths of immediately loade...

  Diameter Length 10 mm 12 mm 14 mm 16 mm Axial ...

About this article : Six-implant-supported immedia...

Wentaschek, S., Hartmann, S., Walter, C. et al. Six-implant-supported immediate fixed rehabilitation of atrophic edentulous maxillae with tilted distal implants. Int J Implant Dent 3, 35 (2017). https://doi.org/10.1186/s40729-017-0096-0 Download citation Received: 14 March 2017 Accepted: 13 July 2017 Published: 25 July 2017 DOI: https://doi.org/10.1186/s40729-017-0096-0

Rights and permissions : Six-implant-supported imm...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Six-implant-supported immedi...

The retrospective data analysis was conducted in accordance with the Helsinki Declaration of 1975, as revised in 2008, and all patients signed an informed consent. After consulting the local ethic committee, the decision was that due to the retrospective character of this study, with no additional data acquisition, no ethical approval is needed according to the hospital laws of the appropriate sta...

Author information : Six-implant-supported immedia...

Department of Prosthetic Dentistry, University Medical Center of the Johannes Gutenberg-University Mainz, Augustusplatz 2, 55131, Mainz, Germany S. Wentaschek & S. Hartmann Department of Oral and Maxillofacial Surgery - Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Augustusplatz 2, 55131, Mainz, Germany C. Walter & W. Wagner You can also search for ...

Acknowledgements : Six-implant-supported immediate...

The authors would like to thank Bredent Medical (Senden, Germany) for providing the 3D-planning system and supporting the treatment nonfinancially.

References : Six-implant-supported immediate fixed...

Download references

References : Six-implant-supported immediate fixed...

Bayer G, Kistler F, Kistler S, Adler S, Neugebauer J. Sofortversorgung mit reduzierter Implantatanzahl: Wissenschaftliche Konzeption und klinische Ergebnisse. Berlin: Quintessenz; 2011. Hanley JA. Receiver operating characteristic (ROC) methodology: the state of the art. Crit Rev Diagn Imaging. 1989;29(3):307–35. Atieh MA, Alsabeeha NH, Payne AG, de Silva RK, Schwass DS, Duncan WJ. The prognos...

References : Six-implant-supported immediate fixed...

Pommer B, Mailath-Pokorny G, Haas R, Busenlechner D, Furhauser R, Watzek G. Patients’ preferences towards minimally invasive treatment alternatives for implant rehabilitation of edentulous jaws. Eur J Oral Implantol. 2014;7(Suppl 2):S91–109. Monje A, Suarez F, Galindo-Moreno P, Garcia-Nogales A, Fu JH, Wang HL. A systematic review on marginal bone loss around short dental implants (

Abbreviations : Six-implant-supported immediate fi...

Area under the curve Implant stability quotient Periotest Receiver operating characteristic

Conclusions : Six-implant-supported immediate fixe...

Within the limits of this small group (n = 10 patients/60 implants), the failure rate of the analyzed implant system (n = 3 respective 5% implant loss) seems to be comparable with other immediate-loading protocols. On the other side, the implant loss rate of tilted implants (n = 2 of 20) in the atrophic upper jaw was quite high, but still, the aimed treatment concept could be achieved in eve...

Discussion : Six-implant-supported immediate fixed...

Between baseline and first removal of the temporary restoration after 3 months, the mean ISQ increased and the mean PT value decreased significantly in the axial and tilted implants. This is in contrast to some other studies which evaluated no significant differences of stability parameters between primary and secondary stability with immediate loading in edentulous maxilla [16, 21, 22]. The pre...

Discussion : Six-implant-supported immediate fixed...

The overall implant survival rate of 95% is slightly lower than the reported mean survival rates of the concept of tilted implants and immediate loading in edentulous jaws [11] but still close to them and maybe more comparable to investigations in which implants were also immediately loaded in the edentulous maxilla which were partly placed in fresh extraction sites [15, 16]. Nevertheless, what is...

Results : Six-implant-supported immediate fixed re...

After the temporary restoration with a fixed prosthesis, all 10 patients selected a fixed final restoration. These consisted of a cast metal framework with a full ceramic veneering including the replacement of at least the second premolars. They were made after a new impression on the abutment level (Figs. 6 and 7). The neck of the 20 tilted distal implants was positioned in region 4 (n = 5 impl...

Results : Six-implant-supported immediate fixed re...

Ten patients with a mean age at implant insertion of 64 ± 11.3 years (range 38 to 81 years; six women, four men) were included. Sixty titanium screw implants (Table 1) were inserted and immediately loaded between 09/2009 and 01/2013. Seven patients had remaining teeth until implant surgery (two patients with 4, four patients with 7, and one patient with 12 teeth). Twenty-one (35%) of the 60 ...

Methods : Six-implant-supported immediate fixed re...

Changes in marginal bone level were measured using the routinely made digital panoramic radiographs if these were available. The measurement tool was calibrated with the known respective implant length. To evaluate the bone loss, the difference was formed between the bone level at follow-up examination (Fig. 5) and at implant placement which is the baseline. An implant was considered as successfu...

Methods : Six-implant-supported immediate fixed re...

The patients were screened with preliminary panoramic radiographs, and since all the implants were 3D planned (SKYplanX™ program, Bredent GmbH, Senden, Germany) and inserted with a guiding template, a cone-beam CT (CBCT) was obtained eventually (KaVo 3D eXam™ unit, KaVo Dental GmbH, Biberach/Riss, Germany). The drillings were performed using a 3D-planned surgical template with different metal...

Methods : Six-implant-supported immediate fixed re...

In a retrospective study, all patients with immediately loaded implants in an edentulous maxillae with limited posterior ridge dimensions that received an equal concept were included if they had a follow-up of at least 3 years. The concept contained immediate loading with distal tilted implants and six implants per edentulous maxillae of a single implant system (blueSky™ implants, Bredent GmbH,...

Background : Six-implant-supported immediate fixed...

For a few years, there has been a trend towards minimally invasive implant treatment concepts avoiding bone augmentation even in very atrophic edentulous jaws. These concepts aim to make an implant treatment with a shorter duration, with less inconvenience such as swelling or pain and possibly also economically more attractive [1]. If the implant treatment is less invasive, because of the possible...

Abstract : Six-implant-supported immediate fixed r...

The aim of this retrospective study was to evaluate the treatment outcome of six Bredent blueSky™ implants (Bredent GmbH, Senden, Germany) immediately loaded with a fixed full-arch prosthesis (two tilted posterior and four axial frontal and premolar implants). All 10 patients with atrophic edentulous maxillae being treated with a standardized procedure from 09/2009 to 01/2013, who had a follow-...

Fig. 5. Change in BoP values according to the perc...

Fig. 5. Change in BoP values according to the percentage of sites with a score of 1, 2 or 3 by visit Fig. 5. Change in BoP values according to the percentage of sites with a score of 1, 2 or 3 by visit

Fig. 4. Percentages of sites with PPD 1–3, 4–5...

Fig. 4. Percentages of sites with PPD 1–3, 4–5 and ≥6 mm by visit (p 

Fig. 3. Changes in BoP values between baseline and...

Fig. 3. Changes in BoP values between baseline and the various examination time points Fig. 3. Changes in BoP values between baseline and the various examination time points

Fig. 2. Changes in PPD values between baseline and...

Fig. 2. Changes in PPD values between baseline and the various examination time points Fig. 2. Changes in PPD values between baseline and the various examination time points

Fig. 1. A chitosan brush (LBC, BioClean®, LABRIDA...

Fig. 1. A chitosan brush (LBC, BioClean®, LABRIDA AS) seated in an oscillating dental handpiece Fig. 1. A chitosan brush (LBC, BioClean®, LABRIDA AS) seated in an oscillating dental handpiece

Table 3 Level of crown margin at the different tim...

  Baseline n = 306 2 weeks n = 272 4 weeks n = 267 12 weeks n = 282 24 weeks n = 294 P ...

Table 2 Demographics by center : A novel non-surgi...

Center Oslo Jonkoping Rome Stavanger Kristianstad Tons...

Table 1 Demographics : A novel non-surgical method...

Variable Number (%) SD Range (min; max) Gender (female/male) 45/18 (71.4/28.6)  ...

About this article : A novel non-surgical method f...

Wohlfahrt, J.C., Evensen, B.J., Zeza, B. et al. A novel non-surgical method for mild peri-implantitis- a multicenter consecutive case series. Int J Implant Dent 3, 38 (2017). https://doi.org/10.1186/s40729-017-0098-y Download citation Received: 08 April 2017 Accepted: 13 July 2017 Published: 03 August 2017 DOI: https://doi.org/10.1186/s40729-017-0098-y

Rights and permissions : A novel non-surgical meth...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : A novel non-surgical method ...

J.C. Wohlfahrt is the inventor and patent holder of BioClean and is a shareholder in LABRIDA AS. B.J. Evensen, B. Zeza, H. Jansson, A. Pilloni, A.M. Roos-Jansåker, G.L. Di Tanna, A.M. Aass, M. Klepp and O.C. Koldsland state that there were no conflicts of interests during the undertaking of the study. Ethical approval was provided by the regional ethical review boards of each center (Norway: 201...

Author information : A novel non-surgical method f...

You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar JCW, BJE, BZ, HJ, AP, AMR-J, AMA, MK and OCK par...

Author information : A novel non-surgical method f...

Department of Periodontology, Institute of Clinical Dentistry, University of Oslo, Pb. 1109 Blindern, 0317, Oslo, Norway J. C. Wohlfahrt, A. M. Aass & O. C. Koldsland Private Practice, Tønsberg, Norway B. J. Evensen Department of Dental and Maxillofacial Sciences, Section of Periodontology, Sapienza, University of Rome, Rome, Italy B. Zeza & A. Pilloni Center for Oral Health, Departmen...

References : A novel non-surgical method for mild ...

Salvi GE, et al. Reversibility of experimental peri-implant mucositis compared with experimental gingivitis in humans. Clin Oral Implants Res. 2012;23(2):182–90. Korsch M, Obst U, Walther W. Cement-associated peri-implantitis: a retrospective clinical observational study of fixed implant-supported restorations using a methacrylate cement. Clin Oral Implants Res. 2014;25(7):797–802. Download ...

References : A novel non-surgical method for mild ...

Muthukuru M, et al. Non-surgical therapy for the management of peri-implantitis: a systematic review. Clin Oral Implants Res. 2012;23(Suppl 6):77–83. Esposito M, Grusovin MG, Worthington HV. Treatment of peri-implantitis: what interventions are effective? A Cochrane systematic review. Eur J Oral Implantol. 2012;5(Suppl):S21–41. Armitage GC, Xenoudi P. Post-treatment supportive care for the n...

References : A novel non-surgical method for mild ...

Rokn A, et al. Prevalence of peri-implantitis in patients not participating in well-designed supportive periodontal treatments: a cross-sectional study. Clin Oral Implants Res. 2017;28(3):314–9. Faggion CM Jr, et al. A systematic review and Bayesian network meta-analysis of randomized clinical trials on non-surgical treatments for peri-implantitis. J Clin Periodontol. 2014;41(10):1015–25. Me...

References : A novel non-surgical method for mild ...

Koldsland OC, Scheie AA, Aass AM. Prevalence of peri-implantitis related to severity of the disease with different degrees of bone loss. J Periodontol. 2010;81(2):231–8. Roos-Jansaker AM, et al. Nine- to fourteen-year follow-up of implant treatment. Part II: presence of peri-implant lesions. J Clin Periodontol. 2006;33(4):290–5. Derks J, et al. Effectiveness of implant therapy analyzed in a ...

Conclusions : A novel non-surgical method for mild...

In this multicenter case series of implants affected by mild peri-implantitis, significant reductions in the clinical parameters of inflammation were demonstrated at all time points after the initial treatment with a chitosan brush. The use of an oscillating chitosan device appears to be safe and has potential merits for the treatment of mild peri-implantitis and for the maintenance of dental impl...

Conclusions : A novel non-surgical method for mild...

In this multicenter case series of implants affected by mild peri-implantitis, significant reductions in the clinical parameters of inflammation were demonstrated at all time points after the initial treatment with a chitosan brush. The use of an oscillating chitosan device appears to be safe and has potential merits for the treatment of mild peri-implantitis and for the maintenance of dental impl...

Discussion : A novel non-surgical method for mild ...

The chitosan brush used in this study is made of a material that is soft with the aim to make a device optimized for removal of the biofilm within the implant threads. The soft bristles on the contrary make the device suboptimal for removal of hard deposits, such as calculus and cement remnants. It has been reported that such cement remnants are a common finding around dental implants [41], and in...

Discussion : A novel non-surgical method for mild ...

In the present study, significant reductions were observed in the clinical parameters of peri-implant inflammation at 2, 4, 12 and 24 weeks relative to baseline after debridement with the chitosan brush seated in an oscillating dental drill piece. No progression in radiographic bone loss was reported at any of the implants at the final evaluation, and the method was thus judged safe to use in cas...

Discussion : A novel non-surgical method for mild ...

Identifying peri-implant disease at an early stage and promptly treating the inflammatory condition is crucial to prevent the progression of peri-implant bone loss and ensure long-term implant survival [23,24,25]. After completion of active treatment and when the condition is controlled, supportive peri-implant therapy will reduce the risk of disease re-occurrence [9]. A number of scientific repor...

Results : A novel non-surgical method for mild per...

During this study, all 63 implants were reported to have stable radiographic levels of osseous support as validated by the six different local examiners. No adverse events were reported during the study.

Results : A novel non-surgical method for mild per...

In total, 63 implants in 63 patients were ultimately included in the analysis. Demographic information is presented in Tables 1 and 2. Significant reductions in both PPD and mBoP were seen at all time points relative to the baseline clinical measurements (p 

Case presentation : A novel non-surgical method fo...

Mann-Whitney rank sum tests were used to compare changes in the clinical parameters between baseline and subsequent time points. To assess the hierarchical structure of the data (center > patient > site), a linear mixed model using the restricted maximum likelihood method (multilevel logistic models for binary outcomes) was constructed to analyse the PPD, mBoP and suppuration, adjusting for fac...

Case presentation : A novel non-surgical method fo...

All patient-related information and clinical recordings were recorded in a web-based clinical research form (VieDoc version 3.24, PCG solutions, Uppsala, Sweden). Patients under 18 years of age; current smokers; patients who had undergone radiotherapy in the head and neck region, chemotherapy or systemic long-term corticosteroid treatment; patients who were pregnant or nursing; patients receivin...

Case presentation : A novel non-surgical method fo...

A 6-month multicenter prospective consecutive case series was performed in six different periodontal specialist clinics in Norway, Sweden and Italy. Ethical approval was provided by the regional ethical review boards of each center (Norway: 2014/852/REK sør-øst; Italy: Sapienza 2011/15, 3547; and Sweden: EPN Lund 2014/695.) Fifteen patients at each center were planned to be included in the stud...

Background : A novel non-surgical method for mild ...

A number of other studies also report that leaving fragments of the instrument on the implant surface or scratching the surface may impede optimal peri-implant healing [17,18,19,20]. Chitosan is a marine biopolymer which is based on chitin derived from the shells of marine crustaceans. The material has been approved for use in surgical bandages, as a haemostatic agent and as a dietary supplement ...

Background : A novel non-surgical method for mild ...

Inflammation and loss of attachment around dental implants (i.e. peri-implantitis) has become a growing concern within the field of dental implantology [1,2,3,4,5,6,7]. Peri-implantitis is a microbial infection-driven soft tissue inflammation with loss of bony attachment around an implant. Peri-implant mucositis is the precursor of peri-implantitis, as gingivitis is for periodontitis [8]. It is cl...

Abstract : A novel non-surgical method for mild pe...

The aim of the present study was to evaluate the effect on peri-implant mucosal inflammation from the use of a novel instrument made of chitosan in the non-surgical treatment of mild peri-implantitis across several clinical centers. In this 6-month multicenter prospective consecutive case series performed in six different periodontal specialist clinics, 63 implants in 63 patients were finally inc...

Fig. 4. Scatterplot depicting indirect calculated ...

Fig. 4. Scatterplot depicting indirect calculated and direct measured ISQ values of the tested implants Fig. 4. Scatterplot depicting indirect calculated and direct measured ISQ values of the tested implants

Fig. 3. Example of a typical autospectrum pointing...

Fig. 3. Example of a typical autospectrum pointing to a 1 maximum RF based on 1000 measurements in case of a Straumann test implant Fig. 3. Example of a typical autospectrum pointing to a 1 maximum RF based on 1000 measurements in case of a Straumann test implant

Fig. 2. Clamped Osstell probe orientated towards a...

Fig. 2. Clamped Osstell probe orientated towards a Smartpeg mounted on a test implant. Note the red laser beam dot on the flat surface of the Smartpeg hexagon part Fig. 2. Clamped Osstell probe orientated towards a Smartpeg mounted on a test implant. Note the red laser beam dot on the flat surface of the Smartpeg hexagon part

Fig. 1. Concept for study of deflection and stiffn...

Fig. 1. Concept for study of deflection and stiffness aspects of implant-Smartpeg complex by laser Doppler vibrometry. Intentional partial imbedding of implants allows to detect both the deflection of implant and Smartpeg separately at different vertical levels by changing the position of the laser beam Fig. 1. Concept for study of deflection and stiffness aspects of implant-Smartpeg complex ...

Table 2 Mean values (± SD) of recorded maximum ...

Batch # Implant system Implant length (mm) Implant diameter (mm) Mean measured resonance freq (kHz) SD meas...

Table 1 Published secondary implant stability valu...

Author and study Implant position (implant number) Mean ISQ values at given time-point post-insertion Type of Osstell device used Barewal et al. 2003 [10] ...

About this article : ISQ calculation evaluation of...

Debruyne, S., Grognard, N., Verleye, G. et al. ISQ calculation evaluation of in vitro laser scanning vibrometry-captured resonance frequency. Int J Implant Dent 3, 44 (2017). https://doi.org/10.1186/s40729-017-0105-3 Download citation Received: 11 April 2017 Accepted: 28 September 2017 Published: 12 October 2017 DOI: https://doi.org/10.1186/s40729-017-0105-3

Rights and permissions : ISQ calculation evaluatio...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : ISQ calculation evaluation o...

Stijn Debruyne, Nicolas Grognard, Gino Verleye, Korneel Van Massenhove, Dimitrios Mavreas, and Bart Vande Vannet declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : ISQ calculation evaluation of...

Correspondence to Nicolas Grognard.

Author information : ISQ calculation evaluation of...

Department of Mechanics, Research Group Propolis, School of Engeneering Sciences, Katholieke Hoge School Brugge-Oostende, Ostend, Belgium Stijn Debruyne Kliniek Royal, Koningstraat 41, 8400, Ostend, Belgium Nicolas Grognard CHIR-Unit Dentistry–ORHE, Department of Orthodontics, Faculty of Medicine and Pharmacy, Vrije Universiteit Brussel, Laarbeeklaan 103, 1090, Brussels, Belgium Nicolas Gro...

References : ISQ calculation evaluation of in vitr...

Han J, Lulic M, Lang NP. Factors influencing resonance frequency analyis assessed by Osstell Mentor during implant issue integration: II: implant surface modifications and implant diameter. Clin Oral Implants Res. 2010;6:605–11. Bornstein M, Hart C, Halbritter S, Morton D, Buser D. Early loading of nonsubmerged titanium implants with a chemically modified sand-blasted and acid-etched surface: 6...

References : ISQ calculation evaluation of in vitr...

Adell R, Lekholm U, Brånemark PI. Surgical procedures. In: Brånemark PI, Zarb GA, Albrektsson T, editors. Tissue integrated prothese. Osseointegration in clinical dentistry. Chigaco: Quintessence; 1985. p. 211–32. Strid K. Radiographic procedures. In: Brånemark P-I, Zarb G, Albrektsson T, editors. Tissue integrated prothese. Osseointegration in clinical dentistry. Chigaco: Quintessence; 1985...

Conclusions : ISQ calculation evaluation of in vit...

In conclusion, the present study demonstrated that the algorithm applied and provided by Osstell to calculate ISQ values is correct, making the laboratory procedure valuable for future research focused on stiffness aspects of the implant-Smartpeg complex and its possible influence on the overall RFA measurement. Vice versa, the present study demonstrates the correctness of the actual applied algor...

Discussion : ISQ calculation evaluation of in vitr...

The focus of this in vitro study was to develop a laboratory method, intended for future research of aspects of implant-Smartpeg complex stiffness and its possible influence on the overall RFA-based implant stability determination. In the past, other laboratory methodologies have been engineered to investigate implant deflection and/or lateral displacement by means of transducers. A setup using a ...

Results : ISQ calculation evaluation of in vitro l...

Mean values (± SD) of recorded maximum RF values, calculated indirect ISQ values, and direct recorded ISQ values for Ankylos (A) and Straumann (S) test implants are shown in Table 2. Using the Shapiro-Wilk test for indirect ISQ (p = 0.05) and direct ISQ (p = 0.02), we can conclude that both indirect and direct ISQ measures are not drawn from a normal distribution (data not shown). Bot...

Methods : ISQ calculation evaluation of in vitro l...

In total, for each given implant type with a given diameter/length configuration, 25 measurements for indirect and 5 measurements for direct ISQ computing were performed. The SPSS statistical software package 22.0 (IBM SPSS, Chicago, USA) was used. A Shapiro-Wilk test was used to verify distribution normality for both direct and indirect determined ISQ values. The paired sample t test and the Wil...

Methods : ISQ calculation evaluation of in vitro l...

The Smartpeg excitation mode was exactly performed as described above. Notation of the maximum resonance frequency for indirect measurements is followed by notation of direct ISQ value on the display of Osstell IDx device. Positioning of the probe was not changed during indirect and direct recordings for a given test implant. Each resin block contained five identical implants with attached Smartp...

Methods : ISQ calculation evaluation of in vitro l...

Test implants originating from various manufacturers were investigated. Straumann sandblasted, large-grit, acid-etched (SLA)® tissue level standard implants (Straumann AG, Basel, Switzerland) with the following diameter: length configurations were 3.3–12 mm (RN connection), 3.3–4.1 mm (RN connection), and 4.8–8 mm (WN connection), Ankylos Cell Plus® surfaced B-implant types (Dentsply Im...

Background : ISQ calculation evaluation of in vitr...

Laser Doppler vibrometry possesses a working principle based on the so-called Doppler effect and allows non-contact quantitative measurement of vibration (https://en.wikpedia.org/wiki/Laser_scanning_vibrometry, 2017). The Doppler effect itself finds its origin when a light beam is backscattered on a vibrating surface and experiences a change in wave phase (https://en.wikipedia.org/wiki/Doppler_eff...

Background : ISQ calculation evaluation of in vitr...

The computed ISQ value is based on the following calculation formulae: Hereby, f denotes the measured maximum resonance frequency (RF). Coefficients a, b, c, d, and e are property information of Osstell (Osstell AB, Gothenburg, Sweden). The coefficients were provided for internal use under the agreement of no publication. From clinical reports [10,11,12,13,14,15,16] listed in Table 1, it ...

Background : ISQ calculation evaluation of in vitr...

At present, multiple implant stability assessment methodologies are used, both of invasive and non-invasive nature, including percussion test [1], X-ray evaluation [2], cutting resistance during implant insertion (e.g., electronic insertion torque determination) [3], turn-out or reverse torque test [4], Periotest® [5, 6], and resonance frequency analysis (“RFA”), e.g., the Osstell method [7, ...

Abstract : ISQ calculation evaluation of in vitro ...

Implant stability testing at various stages of implant therapy by means of resonance frequency analysis is extensively used. The overall measurement outcome is a function of the resulting stiffness of three entities: surrounding bone, bone-implant complex, and implant-Smartpeg complex. The influence of the latter on the overall measurement results is presently unknown. It can be investigated in vi...

Table 6 Correlations between PPD and the other par...

Parameters H group correlation (R s ) HP group correlation (R s ) PPD-mPI 0.182 n.s. ...

Table 5 Correlations between PPD and characteristi...

Characteristics H group correlation (R s ) HP group correlation (R s ) Age 0.040 n.s. 0.209* Number of teeth (at the beginning o...

Table 4 Value of each clinical parameter : Correla...

Clinical parameters H group (n = 39) mean ± SD/median HP group (n = 91) mean ± SD/median Significance difference between H and HP group ...

Table 3 Prevalence of peri-implantitis and periodo...

Diagnosis in HP group (37 patients, 91 implants) Localized: ≤ 30% of site involved, generalized: > 30% of site involved Numbers of peri-implantitis and prevalence in diagnosis n = 14, 15.4% of HP group ...

Table 2 Characteristics of the study population : ...

  H group mean ± SD, or n (median) HP group mean ± SD, or n (median) Significant difference between H and HP group Age 56.0 ± 11.8 (57.9) ...

Table 1 Implant systems used : Correlations betwee...

Implant Number Replace select ™ 44 Novel Replace ® 31 ...

About this article : Correlations between clinical...

Seki, K., Nakabayashi, S., Tanabe, N. et al. Correlations between clinical parameters in implant maintenance patients: analysis among healthy and history-of-periodontitis groups. Int J Implant Dent 3, 45 (2017). https://doi.org/10.1186/s40729-017-0108-0 Download citation Received: 25 July 2017 Accepted: 19 October 2017 Published: 30 October 2017 DOI: https://doi.org/10.11...

Rights and permissions : Correlations between clin...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Correlations between clinica...

Patient recruitment and data collection for this study took place at Nihon University School of Dentistry Dental Hospital, Japan. The research was approved by the Nihon University School of Dentistry Ethics Committee (2013-15) and all activities were conducted in full accordance with ethical principles, including the World Medical Association Declaration of Helsinki. We described the purpose of th...

Author information : Correlations between clinical...

Implant Dentistry, Nihon University School of Dentistry Dental Hospital, Tokyo, 101-8310, Japan Keisuke Seki, Shinya Nakabayashi, Atsushi Kamimoto & Yoshiyuki Hagiwara Department of Comprehensive Dentistry and Clinical Education, Nihon University School of Dentistry, 1-8-13 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8310, Japan Keisuke Seki & Atsushi Kamimoto Department of Applied Mathemati...

References : Correlations between clinical paramet...

Download references

References : Correlations between clinical paramet...

Karousis IK, Salvi GE, Heitz-Mayfield LJ, Brägger U, Hämmerle CH, Lang NP. Long-term implant prognosis in patients with and without a history of chronic periodontitis: a 10-year prospective cohort study of the ITI Dental Implant System. Clin Oral Implants Res. 2003;14:329–39. Mengel R, Flores-de-Jacoby L. Implants in patients treated for generalized aggressive and chronic periodontitis: a 3-y...

References : Correlations between clinical paramet...

Monjie A, Aranda L, Diaz KT, Alarcón MA, Bagramian RA, Wang HL, et al. Impact of maintenance therapy for the prevention of peri-implant diseases: a systematic review and meta-analysis. J Dent Res. 2016;95:372–9. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol. 1999;4:1–6. Lang NP, Berglundh T; Working group 4 of Seventh European W...

References : Correlations between clinical paramet...

Esposito M, Hirsch JM, Lekholm U, Thomsen P. Biological factors contributing to failures of osseointegrated oral implants. (I) Success criteria and epidemiology. Eur J Oral Sci. 1998;106:527–51. Ogata Y, Nakayama Y, Tatsumi J, Kubota T, Sato S, Nishida T, et al. Prevalence and risk factors for peri-implant diseases in Japanese adult dental patients. J Oral Sci. 2017;59:1–11. Heitz-Mayfield L...

Abbreviations : Correlations between clinical para...

Bleeding on probing Modified plaque index Probing pocket depth

Conclusions : Correlations between clinical parame...

We examined clinical parameters in patients receiving long-term implant maintenance. There were significant differences between the H and HP groups in age at the time of maintenance, number of natural teeth at the beginning of implant treatment, total number of extracted teeth, and maintenance. The prevalence of implant-based peri-implantitis was 10.8% of all the implants. All implants with peri-i...

Discussion : Correlations between clinical paramet...

A correlation between the PPD of the peri-implant tissue and lesion progression has been reported, similar to that seen with periodontitis [27]. Probing around the implant is useful for evaluating soft tissue inflammation and is considered reproducible [36]. Examination of peri-implant bleeding is reported to have higher diagnostic accuracy than probing around natural teeth [37]. However, because ...

Discussion : Correlations between clinical paramet...

BoP has been used to evaluate inflammatory conditions of periodontal tissue [33] and can also be an important evaluation item for peri-implant tissues. To avoid diagnosing bleeding resulting from strong probing as a false positive, we set the probing pressure to 0.15 N [34]. BoP values were low, with no significant difference between the groups (H group, 0.30; HP group, 0.28). This result was sim...

Discussion : Correlations between clinical paramet...

All the implants with peri-implantitis came from the HP group, not the H group, thus supporting the view that a history of periodontitis is a risk indicator for peri-implantitis. In the diagnosis of periodontitis within the HP group, it is notable that peri-implantitis increased as periodontitis become more severe. This supports the findings of a previous study that reported that the survival rate...

Discussion : Correlations between clinical paramet...

In this study, we reviewed the clinical parameters of 130 implants in 55 patients during ongoing long-term maintenance. We focused on the history of periodontitis and compared the parameters in two groups classified according to a history of periodontitis. A previous study on the prevalence of periodontitis revealed that moderate or severe periodontitis was observed in 64% of people over 65 years...

Results : Correlations between clinical parameters...

Because normality and homoscedasticity were not obtained for each clinical parameter between the two groups, a statistical study was conducted using the nonparametric test (Mann–Whitney U test) for the difference test between the two groups. PPD was recognized to be significantly greater (p 

Results : Correlations between clinical parameters...

Of the 55 subjects, 25 were male and 30 were female (H group: 8/10, HP group: 17/20, respectively). A total of 130 implants (H group 39, HP group 91) were included in the analysis (Table 2). The mean maintenance period was 6 years and 6 months. The average number of natural teeth at the first visit and at the beginning of implant treatment were 25.3 ± 2.9 and 22.4 ± 4.5, respectively. Com...

Methods : Correlations between clinical parameters...

At the time of optional maintenance, the following parameters were measured for each implant. Data collection and analysis were conducted by two operators who were blind to the research purpose and methods. One operator statistically analyzed the final data set. Plaque adhesion (modified Plaque Index: mPI) on the superstructure of the implant was measured on a 4-point scale (0, no plaque; 1, plaq...

Methods : Correlations between clinical parameters...

This study enrolled 55 patients (25 men, 30 women; mean age, 63.53 ± 10.51 years) who visited Nihon University School of Dentistry Dental Hospital for implant maintenance from April to September 2016. The inclusion criteria were treatment at the same hospital with two-stage implant placement before 2015, and ongoing maintenance at 3–6-month intervals after superstructure placement. Patients ...

Background : Correlations between clinical paramet...

Peri-implant diseases are the main biological complication of implant treatment and greatly influence treatment success [1]. Risk indicators for peri-implantitis include a history of periodontitis, poor oral hygiene, and smoking [2,3,4]. Peri-implantitis is often encountered clinically, occurring in 12 to 43% of implants and 28 to 47% of implant patients [5,6,7,8]. Similarities between the patholo...

Abstract : Correlations between clinical parameter...

The pathophysiology and pathology of peri-implantitis remain unclear; however, its similarity to periodontitis has been described. The evaluation of peri-implant tissue and the diagnostic criteria of peri-implant disease are not currently standardized as they are for periodontitis. In this study, we evaluated clinical parameters during the implant maintenance period to determine significant correl...

Fig. 5. a Postoperative orthopantomogram. b Follow...

Fig. 5. Fig. 5. a Postoperative orthopantomogram. b Follow-up orthopantomogram. c Follow-up standard periapical radiogram (implants i42 and i44). d Follow-up standard periapical radiogram (implants i32 and i34)

Fig. 4. a–h Prosthetic restauration—follow-up ...

mandible.) Fig. 4. a–h Prosthetic restauration—follow-up examination. Intraoral and perioral views of a rehabilitated female patient. (She asked explicitly only for implantological treatment in the mandible.)

Fig. 3. a Primary implant stability. The histogram...

Fig. 3. ution of the implant stability quotients (ISQ) for both jaws measured by resonance frequency analysis (Osstell AB, Göteborg, Sweden). b Secondary implant stability. The histogram shows the distribution of the implant stability quotients (ISQ) of osseointegrated implants. According to the measurement implant stability was classified as low with ISQ values  70 [34] Fig. 3. a Primary ...

Fig. 2. Cumulative implant survival over the follo...

Fig. 2. Cumulative implant survival over the follow-up period. The Kaplan-Meyer diagram visualises the analysis of implant survival in the maxilla and in the mandible (log rank test, p = 0.173) over the follow-up period up to 37 months (Table 4) Fig. 2. Cumulative implant survival over the follow-up period. The Kaplan-Meyer diagram visualises the analysis of implant survival in the maxi...

Fig. 1. a Closed short expandable dental implant (...

Fig. 1. he implant-abutment connection is characterised by an internal hexagon for rotation stability, combining the advantages of conical and parallel surfaces to reduce microgaps and micromovement [68]. The microthread concept and platform switching concept are implemented in the implant shoulder to reduce periimplant bone strain [53]. b Manual fixation of the expansion tool. Take note of the...

Table 4 Clinical characteristics of the study coho...

Patient Sex Age (years) Implant position (FDI) Indication categorya Bone quality Prosthetic treatment ...

Table 3 Prosthetic treatment protocol : Novel expa...

Type of prosthetic treatment Session Procedure Fixed denture (bridge) 1 Open impression ...

Table 2 Surgical treatment protocol : Novel expand...

Surgical protocol Bone quality   D1 D2 D3 D4 1. Drilli...

Table 1 Patient recruitment : Novel expandable sho...

Inclusion criteria Exclusion criteria 1. Adult patients, male and female 1. Comorbidity ASA category ≥ III 2. Partially/totally edentulous patients ...

About this article : Novel expandable short dental...

Reich, W., Schweyen, R., Heinzelmann, C. et al. Novel expandable short dental implants in situations with reduced vertical bone height—technical note and first results. Int J Implant Dent 3, 46 (2017). https://doi.org/10.1186/s40729-017-0107-1 Download citation Received: 18 August 2017 Accepted: 12 October 2017 Published: 30 October 2017 DOI: https://doi.org/10.1186/s40...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Additional files : Novel expandable short dental i...

Dataset presenting relevant raw data. (SAV 3 kb)

Ethics declarations : Novel expandable short denta...

WR is a senior physician at the University Hospital Halle, Martin Luther University Halle-Wittenberg, Department of Oral and Plastic Maxillofacial Surgery, Halle/Saale, Germany.RS is a clinical research associate at the University School of Dental Medicine, Department of Prosthetic Dentistry, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.CH is a consultant at the University Hospi...

Ethics declarations : Novel expandable short denta...

WR is a senior physician at the University Hospital Halle, Martin Luther University Halle-Wittenberg, Department of Oral and Plastic Maxillofacial Surgery, Halle/Saale, Germany. RS is a clinical research associate at the University School of Dental Medicine, Department of Prosthetic Dentistry, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany. CH is a consultant at the University H...

Author information : Novel expandable short dental...

Correspondence to Waldemar Reich.

Author information : Novel expandable short dental...

Department of Oral and Plastic Maxillofacial Surgery, Martin Luther University Halle-Wittenberg, Ernst-Grube Str. 40, 06120, Halle (Saale), Germany Waldemar Reich, Christian Heinzelmann, Bilal Al-Nawas & Alexander Walter Eckert University School of Dental Medicine, Department of Prosthetic Dentistry, Martin Luther University Halle-Wittenberg, Magdeburger Straße 16, 06112, Halle (Saale), Ger...

Acknowledgements : Novel expandable short dental i...

The authors are grateful to the DenTack Company for providing some of the implants and components used in this study. The courtesy of Oz Vachtenberg is acknowledged for providing Fig. 1a–f and the movie clip. There are no financial supports or conflicts of interest associated with this publication that could have influenced its outcome. We thank the Osstell Company, which supplied the RFA devic...

References : Novel expandable short dental implant...

Mishra SK, Chowdhary R, Kumari S. Microleakage at different implant abutment interface: a systematic review. J Clin Diagn Res. 2017;11(6):ZE10–5. Feichtinger M, Gaggl A, SChultes G, Kärcher H. Evaluation of distraction implants for prosthetic treatment after vertical alveolar ridge distraction: a clinical investigation. Int J Prosthodont. 2003;16(1):19–24. Pradeep PR, Kasti KJ, Ananthakrish...

References : Novel expandable short dental implant...

Gehrke SA, Pérez-Albacete Martinez C, Piattelli A, Shibli JA, Markovic A, Calvo Guirado JL. The influence of three different apical implant designs at stability and osseointegration process: experimental study in rabbits. Clin Oral Implants Res. 2017;28(3):355–61. Herrero-Climent M, Santos-Garcia R, Jaramillo-Santos R, Romero-Ruiz MM, Fernandez-Palacin Lazaro-Calvo P, Bullon P, Rios-Santos JV....

References : Novel expandable short dental implant...

Malmstrom H, Gupta B, Ghanem A, Cacciato R, Ren Y, Romanos GE. Success rate of short dental implants supporting single crowns and fixed bridges. Clin Oral Implants Res. 2016;27(9):1093–8. Garfield RE. An expandable implant fixture. Dent Implantol Updat. 1998;9(5):37–40. Nowzari H, Chee W, Tuan A, Abou-Rass M, Landesman HM. Clinical and microbiological aspects of the Sargon immediate load imp...

References : Novel expandable short dental implant...

Brenner M, Brandt J, Lauer HC. Prothetische Versorgung auf kurzen Implantaten. Zahnmedizin up2date. 2014;2:123–42. (German) Eitner S, Wichmann M, Schlegel KA, Kollmannberger JE, Nickenig HJ. Oral health-related quality of life and implant therapy: an evaluation of preoperative, intermediate, and post-treatment assessments of patients and physicians. J Craniomaxillofac Surg. 2012;40(1):20–3. ...

References : Novel expandable short dental implant...

De Moraes SL, Verri FR, Santiago JF Jr, Almeida DA, de Mello CC, Pellizzer EP. A 3-D finite element study of the influence of crown-implant ratio on stress distribution. Braz Dent J. 2013;24(6):635–41. Moraes SL, Pellizzer EP, Verri FR, Santiago JF Jr, Silva JV. Three-dimensional finite element analysis on stress distribution in retention screws of different crown-implant ratios. Comput Methods...

References : Novel expandable short dental implant...

Thoma DS, Haas R, Tutak M, Garcia A, Schincaglia GP, Hämmerle CH. Randomised controlled multicenter study comparing short dental implants (6 mm) versus longer dental implants (11-15 mm) in combination with sinus floor elevation procedures. Part 1: demographic and patient-reported outcomes at 1 year of loading. J Clin Periodontol. 2015;42(1):72–80. Hentschel A, Herrmann J, Glauche I, Vollmer A,...

References : Novel expandable short dental implant...

Schwarz F, Terheyden H. Significance of dental implants for health care. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011;54(9):1097–101. (German) Gates WD, Cooper LF, Sanders AE, Reside GJ, De Kok IJ. The effect of implant-supported removable partial dentures on oral health quality of life. Clin Oral Impl Res. 2014;25:207–13. Fretwurst T, Nack C, Al-Ghrairi M, Raguse JD, ...

Abbreviations : Novel expandable short dental impl...

Bone quality (density) World Dental Federation Implant stability quotient Resonance frequency analysis

Conclusion : Novel expandable short dental implant...

Initial results of the ongoing study confirm the feasibility and safety of the employed system. The implant type seems to be useful for all bone qualities and shows high initial and secondary biomechanical stability in the maxilla and mandible. Long-term follow-up will be needed in validating these initial results in a larger 3-year clinical trial. Crestal bone changes should be evaluated in a la...

Discussion : Novel expandable short dental implant...

Comparable studies displayed at 24 months a crestal bone loss of 0.5–0.6 mm [15]. Other authors reported at 2, 3 and 5 years a mean loss of 0.57, 0.55 and 0.53 mm, respectively, in the mandible (without significant change after 1 year) [10]. On the other hand, randomised controlled trials demonstrated 1 year after loading periimplant marginal bone loss of 0.7 mm [70] and 1.1 mm [7] in th...

Discussion : Novel expandable short dental implant...

Contrary to conventional hollow-screw implants (only marginal gap), a problem of the expandable implant is the presence of gaps down to the apical region. Former microbial assessment of different implant-abutment interfaces displayed that none of the marginal connections had the capacity to prevent microbial leakage [63,64,65]. Therefore, an apical microleakage (comparable to distractable implants...

Discussion : Novel expandable short dental implant...

Regarding resonance frequency analysis, the values are related to bone quality and quantity as well as the exposed implant height above the alveolar crest, which depends on the type of implant and insertion technique [55,56,57]. Our results (primary stability in the maxilla 66.9 ± 8.9 ISQ units and in the mandible 72.5 ± 11.1 ISQ units; secondary stability in the maxilla 66.4 ± 10.0...

Discussion : Novel expandable short dental implant...

Several investigators analysed the preferred indications of short dental implants in the posterior mandible or maxilla and outlined the cost efficiency compared to additional vertical augmentations. In the present trial, we used a new short implant in both jaws and nearly all possible indication categories were represented, which proves the broad versatility (Table 4). In our study, two implant ...

Discussion : Novel expandable short dental implant...

Recent literature has shown that short implants have achieved growing acceptance in the field of oral implantology [9, 10, 39, 40]. Since the last years, concern has decreased about the length of endosseous implants; it should be noted that all extraoral screw implants are short implants [41, 42]. Nevertheless, there are local physiological and biomechanical differences regarding long-term stabili...

Results : Novel expandable short dental implants i...

Over the follow-up period, the mean crestal bone changes after loading were as follows (each compared to the baseline): in the first year, 1.0 ± 0.9 mm 95% CI (0.5; 1.5) in the maxilla and 0.7 ± 0.4 mm 95% CI (0.5; 1.0) in the mandible (p = 0.011; independent t test), and in the second year, 1.3 ± 0.8 mm 95% CI (0.8; 1.7) in the maxilla and 1.0 ± 0.7 mm 95% CI (0.6; 1.4...

Results : Novel expandable short dental implants i...

The first results of this longitudinal study include data from 9 patients with an average age of 57 years (range from 44 to 80) in whom 30 implants were inserted (maxilla n = 15, mandible n = 15). All 30 implants in the 9 patients could be inserted without intraoperative problems. Based on intraoperative and radiological findings, the bone quality was assessed as follows: D1 in n = 2,...

Material and methods : Novel expandable short dent...

All patients were pseudonymised, parameters were attached to a databank and analysed statistically (Additional file 2). Statistical analyses were performed using statistics software (IBM SPSS statistics, version 20, Chicago, IL, USA). The descriptive statistics presented the frequency and distribution of several occurrences as well as combinations of certain features. Analytical statistics were p...

Material and methods : Novel expandable short dent...

Simulation of the expansion process. At the end of the expansion process, a minimal snap back is realised. (MP4 9407 kb) Planning of the implantological treatment followed usual clinical and radiological examination and, concerning the position and number of implants, the recommended categories from the German consensus conference [35]. The drilling sequence, condensing preparation (where necess...

Material and methods : Novel expandable short dent...

The study was designed as a prospective monocentric longitudinal cohort study according to the STROBE criteria. The participants of this study were recruited at the university hospital of Martin Luther University Halle-Wittenberg, Department of Oral and Plastic Maxillofacial Surgery, implantological consultation from 2014 (June) until 2015 (June). Inclusion and exclusion criteria of adult patients...

Introduction : Novel expandable short dental impla...

It is known that achievement of primary stability is one precondition for osseointegration and treatment success. There are few reports of immediate [14] and early (6 weeks) functional loading of short implants [28]. This is related to good bone quality, implant design or implant site preparation (e.g. under-drilling). However, under-drilling of the crestal aspect may lead to decreased bone-to-im...

Introduction : Novel expandable short dental impla...

Endosseous implants have been established over several decades. The evaluation of treatment results under biomechanical, physiological, psychological, social and economic aspects has been well documented [1]. Furthermore, patient-based outcomes reveal a predictable gain in oral health-related quality of life [2]. Especially in patients with limited vertical bone height, process of treatment is ex...

Abstract : Novel expandable short dental implants ...

Short implants often have the disadvantage of reduced primary stability. The present study was conducted to evaluate the feasibility and safety of a new expandable short dental implant system intended to increase primary stability. As a “proof of concept”, a prospective clinical cohort study was designed to investigate intraoperative handling, primary and secondary implant stability (resonanc...

Fig. 6. Postoperative intraoral finding and radiog...

Fig. 6. Postoperative intraoral finding and radiograph Fig. 6. Postoperative intraoral finding and radiograph

Fig. 5. High p53, p63, and Ki-67 reactivity are al...

Fig. 5. High p53, p63, and Ki-67 reactivity are also observed in the basal cell layer (immunohistological staining, bar 400 μm) Fig. 5. High p53, p63, and Ki-67 reactivity are also observed in the basal cell layer (immunohistological staining, bar 400 μm)

Fig. 4. Immunohistological findings show a negativ...

Fig. 4. Immunohistological findings show a negative staining mosaic pattern for keratin 13 (k13) and positive staining for keratin 17 (k17) (immunohistological staining, bar 400 μm) Fig. 4. Immunohistological findings show a negative staining mosaic pattern for keratin 13 (k13) and positive staining for keratin 17 (k17) (immunohistological staining, bar 400 μm)

Fig. 3. Pathological microscopic examination revea...

Fig. 3. Pathological microscopic examination reveals thickened squamous epithelia with slight nuclear atypism and disorders of the epithelial rete pegs accompanied by moderate grade inflammatory cell infiltration (HE staining, bar: 400 μm) Fig. 3. Pathological microscopic examination reveals thickened squamous epithelia with slight nuclear atypism and disorders of the epithelial rete pegs a...

Fig. 2. Panoramic radiograph shows slight vertical...

Fig. 2. Panoramic radiograph shows slight vertical bone resorption around the implants in the right side of the mandible Fig. 2. Panoramic radiograph shows slight vertical bone resorption around the implants in the right side of the mandible

Fig. 1. Well-circumscribed gingival swelling on th...

Fig. 1. Well-circumscribed gingival swelling on the lingual side of the right side of the mandible Fig. 1. Well-circumscribed gingival swelling on the lingual side of the right side of the mandible

Table 1 Summary of immunohistochemical findings of...

Antibody Sorce Clone Staining Keratin 13 DAKO DE-K13 ...

About this article : Primary peri-implant oral int...

Noguchi, M., Tsuno, H., Ishizaka, R. et al. Primary peri-implant oral intra-epithelial neoplasia/carcinoma in situ: a case report considering risk factors for carcinogenesis. Int J Implant Dent 3, 47 (2017). https://doi.org/10.1186/s40729-017-0109-z Download citation Received: 15 March 2017 Accepted: 25 October 2017 Published: 16 November 2017 DOI: https://doi.org/10.1186...

Rights and permissions : Primary peri-implant oral...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Primary peri-implant oral in...

Written informed consent was obtained from the patient for publication of this case report and any accompanying images.Makoto Nogchi, Hiroaki Tsuno, Risa Ishizaka, Kumiko Fujiwara, Shuichi Imaue, and Kei Tomihara declare that they have no competing interests.Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Ethics declarations : Primary peri-implant oral in...

Written informed consent was obtained from the patient for publication of this case report and any accompanying images. Makoto Nogchi, Hiroaki Tsuno, Risa Ishizaka, Kumiko Fujiwara, Shuichi Imaue, and Kei Tomihara declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Primary peri-implant oral int...

Correspondence to Makoto Noguchi.

Author information : Primary peri-implant oral int...

Department of Oral and Maxillofacial Surgery, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, 2630 Sugitani Toyama city, Toyama, 9300194, Japan Makoto Noguchi, Hiroaki Tsuno, Risa Ishizaka, Kumiko Fujiwara, Shuichi Imaue & Kei Tomihara Department of Diagnosis Pathology, Graduate School of Medicine and Pharmaceutical Sciences for Research, Univers...

References : Primary peri-implant oral intra-epith...

Vasilescu F, Ceauşu M, Tänsen C, et al. P53, p63 and ki-67 assessment in HPV-induced cervical neoplasia. RJME. 2009;50:357–61. Ndiaye C, Mena M, Alemany L, et al. HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis. Lancet Oncol. 2014;15:1319–31. Nagy K, Sonkodi I, Szöke I, et al. The microflora associated with human oral carcinoma. ...

References : Primary peri-implant oral intra-epith...

Sah JP, Johnson NW, Batsakis JG. Oral cancer. London: Informa Healthcare; 2011. p. 3–32. Japan Society for Oral Tumors. General rules for clinical and pathological studies on oral cancer. 1st ed. Tokyo: Kanehara-shuppan Co; 2010. p. 44–7. Laprise C, Shahl HP, Madathil SA, et al. Periodontal diseases and risk of oral cancer in Southern India: results from the HeNCe Life Study. Int J Cancer. 2...

Abbreviations : Primary peri-implant oral intra-ep...

Deoxyribonucleic acid Human papilloma virus Oral intra-epithelial neoplasia/carcinoma in situ Squamous cell carcinoma

Conclusions : Primary peri-implant oral intra-epit...

In our case, the persistence of peri-implant mucositis or peri-implantitis around the dental implant was implicated as being a plausible risk factor for carcinogenesis. Regular follow-up to ensure the maintenance of oral hygiene after dental implant therapy has again been shown to be important for preventing peri-implantitis, a plausible risk factor for carcinogenesis.

Case presentation : Primary peri-implant oral intr...

The latest evidence implies that the human papilloma virus (HPV) may be responsible for carcinogenesis in the oral cavity [12, 13]; however, its role is debatable. The interaction of the HPV’s E6 and E7 oncoproteins with cell cycle proteins disturbs the cell cycle mechanism and subsequent alteration in the expression of proteins such as p53, p63, and Ki-67 [14]. In our case, the immunohistochemi...

Case presentation : Primary peri-implant oral intr...

OIN/CIS can sometimes be difficult to distinguish pathologically from epithelial dysplasia on hematoxylin- and eosin-staining sections; this has proved challenging for oral pathologists [9]. Recently, it has been reported that combined immunohistochemistry for k13 and k17 was useful for the differential diagnosis [9, 10]. K13 is a marker for cellular differentiation toward prickle cells in normal ...

Case presentation : Primary peri-implant oral intr...

A 65-year-old woman was referred to our clinic with a tumor in the right lower gingiva. Her medical history included breast cancer without metastatic lesion, diabetes mellitus, hyperlipidemia, and hypertension. She had taken orally aspirin, amlodipine, pravastatin, and bepotastine for 2 years. She drank alcohol socially, but she had no history of tobacco smoking habit. About 10 years prior to h...

Background : Primary peri-implant oral intra-epith...

Oral cancer ranks sixth among the malignancies in terms of worldwide prevalence, with more than 90% being pathologically squamous cell carcinoma (SCC) [1]. Oral SCC generally develops via multistep carcinogenesis. The squamous epithelium goes into irreversible change, including epithelial dysplasia and oral intra-epithelial neoplasia/carcinoma in-situ (OIN/CIS) [2], finally resulting in the develo...

Abstract : Primary peri-implant oral intra-epithel...

In this case, prolonged peri-implant mucositis or peri-implantitis may have been a plausible risk factor for carcinogenesis.

Abstract : Primary peri-implant oral intra-epithel...

Major risk factors for oral squamous cell carcinoma (SCC) are tobacco smoking, a betel quid chewing habit, and heavy alcohol consumption. However, around 15% of oral SCCs cannot be explained by these risk factors. Although oral SCC associated with dental implants is quite rare, there has been a recent gradual accumulation of reports about it. Here, we report a case of primary peri-implant oral int...

Fig. 5. SEM images of the mesial margin of abrasio...

Fig. 5. SEM images of the mesial margin of abrasion under topography contrast (a) and material contrast (b) Fig. 5. SEM images of the mesial margin of abrasion under topography contrast (a) and material contrast (b)

Fig. 4. Luting agent located mostly in the crown (...

Fig. 4. Luting agent located mostly in the crown (a) and only sparsely on the implant (b). A crown fragment is remaining on the implant Fig. 4. Luting agent located mostly in the crown (a) and only sparsely on the implant (b). A crown fragment is remaining on the implant

Fig. 3. Area of abrasion (yellow surface) and maxi...

Fig. 3. Area of abrasion (yellow surface) and maximum vertical wear (arrow) Fig. 3. Area of abrasion (yellow surface) and maximum vertical wear (arrow)

Fig. 2. Four replicas on specimen stubs and foam p...

Fig. 2. Four replicas on specimen stubs and foam pellets in the sample holder of the Micro-CT Fig. 2. Four replicas on specimen stubs and foam pellets in the sample holder of the Micro-CT

Fig. 1. Luted crown on embedded implant before che...

Fig. 1. Luted crown on embedded implant before chewing simulation Fig. 1. Luted crown on embedded implant before chewing simulation

Table 3 Stability of conditions across four CS rou...

ANOVA results  Pull-out forces  Maximum wear  Volume wear F (df) 0.02 (3, 16) ...

Table 2 Mean (standard deviation) of assessed para...

CS round (n) Pull-out forces Maximum wear Volume wear #1 (5) 319.6 (75.4) ...

Table 1 Micro-CT scanning parameters of the repli...

Voltage 60 kV Amperage 167 μA Filter No filter ...

About this article : Biomechanical properties of p...

Baumgart, P., Kirsten, H., Haak, R. et al. Biomechanical properties of polymer-infiltrated ceramic crowns on one-piece zirconia implants after long-term chewing simulation. Int J Implant Dent 4, 16 (2018). https://doi.org/10.1186/s40729-018-0127-5 Download citation Received: 16 November 2017 Accepted: 20 March 2018 Published: 23 May 2018 DOI: https://doi.org/10.1186/s4072...

Rights and permissions : Biomechanical properties ...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Biomechanical properties of ...

Not applicable Not applicable Pia Baumgart, Holger Kirsten, Rainer Haak, and Constanze Olms declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Biomechanical properties of p...

Department of Dental Prosthodontics and Materials Science, University of Leipzig, Liebigstraße 12, Haus 1, 04103, Leipzig, Germany Pia Baumgart Institute for Medical Informatics, Statistics, and Epidemiology (IMISE), Haertelstraße 16-18, 04107, Leipzig, Germany Holger Kirsten LIFE Research Center for Civilization Diseases, University of Leipzig, Philipp-Rosenthal-Straße 27, 04103, Leipzig, ...

Acknowledgements : Biomechanical properties of pol...

The authors would like to thank T. Meißner for the lab support. Not applicable The datasets supporting the conclusions of this article are available. Availability of data and materials by the corresponding author: constanze.olms@medizin.uni-leipzig.de

References : Biomechanical properties of polymer-i...

Coldea A, Swain MV, Thiel N. Mechanical properties of polymer-infiltrated-ceramic-network materials. Dent Mater. 2013;29:419–26. Dirxen C, Blunck U, Preissner S. Clinical performance of a new biomimetic double network material. Open Dent J. 2013;7:118–22. Della Bona A, Corazza PH, Zhang Y. Characterization of a polymer-infiltrated ceramic-network material. Dent Mater. 2014;30:564–9. Keul ...

References : Biomechanical properties of polymer-i...

Guess PR, Att W, Strub JR. Zirconia in Fixed Implant Prosthodontics. Clin Implant Dent Relat Res. 2012;14:633-45 Wilson TG Jr. The Positive Relationship Between Excess Cement and Peri-Implant Disease: A prospective Clinical Endoscopic Study. J Periodontol. 2009;80:1388–92. Schwenter J, Schmidli F, Weiger R, Fischer J. Adhesive bonding to polymer infiltrated ceramic. Dent Mater J. 2016;35:796...

Abbreviations : Biomechanical properties of polyme...

Three-dimensional space Analysis of variance Computer-aided design/computer-aided manufacturing confidence interval (exact) according to Clopper-Pearson Chewing simulation degrees of freedom Et alii/et aliae/et alia F test Mean X-ray micro-computed tomography Number p value Polymer-infiltrated ceramic network Standard deviation Scanning electron microscope Vita Enamic

Conclusions : Biomechanical properties of polymer-...

The present study demonstrates that elastic PICN crowns on rigid one-piece zirconia implants seem to be a promising material combination for clinical practice. Though the crowns suffered major wear after CS, the stability was not affected, and no catastrophic failure occurred. However, clinical trials are essential to examine the behavior of the material combination, especially in comparison to ot...

Discussion : Biomechanical properties of polymer-i...

The missing comparison to other PICN materials can be considered a limitation of the study. Since VE is a unicum in the family of PICN materials, it is difficult to find an appropriate material of comparison, especially since Lava Ultimate (3M Espe), a resin nanoceramic, is no longer indicated as a crown material due to a high rate of loosening. The review of Mainjot et al. reported that the loose...

Discussion : Biomechanical properties of polymer-i...

In the study of Naumova et al., volume and vertical wear of PICN crowns, compared to other materials such as a nanoceramic resin and a lithium silicate reinforced ceramic after CS, were tested [11]. They used the same settings of CS as in the present study, but the crowns were luted to extracted molars instead of implants and extracted molars as antagonists were used as well. Concerning volume and...

Discussion : Biomechanical properties of polymer-i...

To the best of our knowledge, it was the first time that the biomechanical properties of polymer-infiltrated ceramic crowns on one-piece zirconia implants after long-term chewing simulation were examined. The present in vitro study investigated the biomechanical properties concerning surface wear and bond strength. No fractures occurred during long-term chewing simulation, and the abrasion of the ...

Results : Biomechanical properties of polymer-infi...

No failure occurred as none of the tested crowns or implants was fractured or loosened during or after CS. The tested crowns showed a maximum wear depth of M = 0.31 ± 0.04 mm (mean ± SD) and volume wear of M = 0.74 ± 0.23 mm3 (mean ± SD). Table 2 shows the mean and standard deviation of assessed parameters (pull-out forces, maximum wear, volume wear) of each round o...

Methods : Biomechanical properties of polymer-infi...

For volume assessment of abrasion, each 3D data set was segmented before and after CS in CTAn (CTAnalyzer V.1.15.4.0, Bruker microCT). Both data sets were overlapped, and the remaining volume of abrasion quantified in pixels and converted into cubic millimeters. The maximum wear depth was determined by “blowing up” virtual bullets within the surface of abrasion. The diameter of the most massi...

Methods : Biomechanical properties of polymer-infi...

The specimens attached to the parallelometer were perpendicularly recessed until only the upper coils of the implants were on view. To produce replicas of the specimens from the experimental group, the crowns’ occlusal was cast using VPS Hydro Putty und VPS Hydro Light Body (Henry Schein Inc., New York, USA) before and after CS. The impression was grouted with Stycast 1266 (Loctite Henkel Elect...

Methods : Biomechanical properties of polymer-infi...

Twenty-five PICN crowns (Vita Enamic, Vita Zahnfabrik, Bad Säckingen, Germany) for premolars were produced using CAD/CAM technology and polished with the Vita Enamic Polishing Set Technical (Vita Zahnfabrik) as recommended by the manufacturer. All crowns were bonded to identical one-piece zirconia testing implants. The implants were turned from pre-sintered zirconia blocks (VITA In-Ceram® 2000 ...

Background : Biomechanical properties of polymer-i...

The demand for tooth-colored dental restorations has increased rapidly within the last few years. Ceramic restorations can often meet these requirements. In dental implantology, zirconia especially—due to its esthetical advantage as well as high flexural strength and outstanding biocompatibility—has gained importance [1]. On the other hand, one-piece zirconia implants are not yet commonly use...

Abstract : Biomechanical properties of polymer-inf...

Implant and superstructure provide a complex system, which has to withstand oral conditions. Concerning the brittleness of many ceramics, fractures are a greatly feared issue. Therefore, polymer-infiltrated ceramic networks (PICNs) were developed. Because of its high elastic modulus, the PICN crown on a one-piece zirconia implant might absorb forces to prevent the system from fracturing in order ...

Fig. 4. Cross-sectional images of areas 1–3 of a...

Fig. 4. Cross-sectional images of areas 1–3 of a 39-year-old female. The visibility ratios for the superior wall in areas 1, 2, and 3 were 0.2, 0.9, and 0.9, respectively, whereas those of the inferior wall were 0.7, 0.9, and 1.0, respectively Fig. 4. Cross-sectional images of areas 1–3 of a 39-year-old female. The visibility ratios for the superior wall in areas 1, 2, and 3 were 0.2, 0.9...

Fig. 3. Visibility ratios of the superior and infe...

Fig. 3. Visibility ratios of the superior and inferior walls in three areas. The Friedman test and Scheffe’s test were used for the statistical analysis Fig. 3. Visibility ratios of the superior and inferior walls in three areas. The Friedman test and Scheffe’s test were used for the statistical analysis

Fig. 2. Visibilities of the superior and inferior ...

Fig. 2. Visibilities of the superior and inferior walls of the mandibular canal. a Both walls are visible. b Only the inferior wall is visible. c Neither of the walls is visible Fig. 2. Visibilities of the superior and inferior walls of the mandibular canal. a Both walls are visible. b Only the inferior wall is visible. c Neither of the walls is visible

Fig. 1. Cross-sectional images in the range of 30...

Fig. 1. Cross-sectional images in the range of 30 mm just distal to the mental foramen were used for evaluation. The range was divided into three areas, each of which was 10 mm in length, designated as area 1, area 2, and area 3, from anterior to posterior. (The mental foramen was identified on another section and was not visualized on this image) Fig. 1. Cross-sectional images in the range...

Table 3 Frequency of cases with visibility ratio o...

  Number of cases Mandibular canal wall Area 1 Area 2 Area 3 Superior wall ...

Table 2 Mean visibility ratio ± SD : Diagnost...

NoneTable 2 Mean visibility ratio ± SD

Table 1 κ-values for interobserver agreement : Di...

Mandibular canal wall Area 1 Area 2 Area 3 Superior wall 0.7795 ...

About this article : Diagnostic ability of limited...

Ishii, H., Tetsumura, A., Nomura, Y. et al. Diagnostic ability of limited volume cone beam computed tomography with small voxel size in identifying the superior and inferior walls of the mandibular canal. Int J Implant Dent 4, 18 (2018). https://doi.org/10.1186/s40729-018-0133-7 Download citation Received: 20 December 2017 Accepted: 23 April 2018 Published: 26 July 2018 D...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Diagnostic ability of limite...

All procedures followed were in accordance with the ethical standards of the responsible committees on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. The study was approved by an institutional review board of our university (approval No. D2016-061). The requirement for informed consent from each patient was waived in this retrospect...

Author information : Diagnostic ability of limited...

Correspondence to Akemi Tetsumura.

Author information : Diagnostic ability of limited...

Department of Oral and Maxillofacial Radiology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan Hiroko Ishii, Akemi Tetsumura, Yoshikazu Nomura, Shin Nakamura & Tohru Kurabayashi URA, Research Administration Division, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan Masako Akiyama Yo...

Availability of data and materials : Diagnostic ab...

The datasets during and/or analyzed during the current study are available from the corresponding author on reasonable request.

References : Diagnostic ability of limited volume ...

Bertl K, Heimel P, Reich KM, Schwarze UY, Ulm C. A histomorphometric analysis of the nature of the mandibular canal in the anterior molar region. Clin Oral Investig. 2014;18:41–7. Starkie C, Stewart D. The intra-mandibular course of the inferior dental nerve. J Anat. 1931;65:319–23. Carter RB, Keen EN. The intramandibular course of the inferior alveolar nerve. J Anat. 1971;108:433–40. Nai...

References : Diagnostic ability of limited volume ...

Faul F, Erdfelder E, Lang A-G, Buchner A. G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods. 2007;39:175–91. Kundel HL, Polansky M. Measurement of observer agreement. Radiology. 2003;228:303–8. Alhassani AA, AlGhamdi AS. Inferior alveolar nerve injury in implant dentistry: diagnosis, causes, prevention, and managem...

References : Diagnostic ability of limited volume ...

Tyndall DA, Price JB, Tetradis S, Ganz SD, Hildebolt C, Scarfe WC. Position statement of the American Academy of Oral and Maxillofacial Radiology on selection criteria for the use of radiology in dental implantology with emphasis on cone beam computed tomography. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;113:817–26. Weckx A, Agbaje JO, Sun Y, Jacobs R, Politis C. Visualization techniques...

Abbreviations : Diagnostic ability of limited volu...

Cone beam computed tomography Field of view

Conclusions : Diagnostic ability of limited volume...

In conclusion, we evaluated the visibility of the mandibular canal walls on limited volume CBCT images with a small voxel size. Evaluation was performed in the range of 30 mm in length just posterior to the mental foramen, which was divided into three equal areas (areas 1, 2, and 3, from anterior to posterior). The superior wall was significantly more poorly visualized than the inferior wall in a...

Discussion : Diagnostic ability of limited volume ...

Our study had some limitations that should be addressed. First, in our study, antero-posterior location of the mandibular canal was defined by the distance from the mental foramen. Tooth positions could not be used as a reference, because premolars and molars were totally or partially missing in considerable number of the cases. Although areas 1–3 were considered mostly to correspond to the area...

Discussion : Diagnostic ability of limited volume ...

Jung and Cho [6] reported that the mandibular canal was clearly visible in 50% of CBCT images in the first molar and in 58% in the second molar region. Similarly, Oliveira-Santos et al. [5] reported that it was visible in 63, 66, and 67% of second premolar, first molar, and second molar regions, respectively. As described above, these studies did not discriminate between the superior and the infer...

Discussion : Diagnostic ability of limited volume ...

In this study, we only used CBCT images of the mandible obtained with the smallest FOV, 40 × 40 mm. On those images, the range of 30 mm in length in the mandible just posterior to the mental foramen was divided into three equal areas, each of which was 10 mm in length. They were designated as areas 1, 2, and 3, from anterior to posterior. After that, the visibilities of the superior and in...

Discussion : Diagnostic ability of limited volume ...

It is very important to know the location of the mandibular canal prior to dental implant surgery to avoid surgical complications including vascular trauma or nerve damage. CBCT is widely accepted to be the imaging method of choice for obtaining this information [1, 2]. However, it is well known that the mandibular canal cannot usually be identified over its entire course even when CBCT is used. ...

Results : Diagnostic ability of limited volume con...

Interobserver agreement was substantial or almost perfect agreement (Table 1). The mean values of the visibility ratio of the superior and inferior walls in each area are shown in Table 2 and Fig. 3. In all areas, the ratio of the superior wall was significantly lower than that of the inferior wall (p = 0.0000). As for variance among the three areas, the ratio was highest in the most poste...

Methods : Diagnostic ability of limited volume con...

The ratio ranged from 0 to 1. Sample size was determined using the free software G* Power 3.1 [11]. We evaluated 30 patients, and the effect size was calculated from the mean, standard deviation, and correlation. Wilcoxon signed-rank sum test was chosen, and the significance level was set to 0.05. The result showed that a sample size of 26 to 75 patients would provide a power of at least 0.8 for ...

Methods : Diagnostic ability of limited volume con...

This study was approved by an institutional review board of our university (D2016-061). Among the patients whose mandibles were examined by CBCT at our dental hospital between April 2012 and August 2016, 96 patients who fulfilled the following two conditions were selected. On CBCT imaging: The smallest field of view (FOV) of the device, 40 × 40 mm, was used. The mental foramen and the ma...

Background : Diagnostic ability of limited volume ...

The mandibular canal is an important anatomical structure that contains the neurovascular bundle, i.e., the inferior alveolar nerve and artery. The location of the mandibular canal must be correctly identified prior to dental implant surgery to avoid complications including intraoperative and postoperative hemorrhage and neurosensory loss. Cone beam computed tomography (CBCT) is considered the ima...

Abstract : Diagnostic ability of limited volume co...

The aim of this study was to evaluate the visibility of the superior and inferior walls of the mandibular canal separately using limited volume cone beam computed tomography (CBCT) with small voxel size. CBCT cross-sectional images of 86 patients obtained by 3D Accuitomo FPD and reconstructed with a voxel size of 0.08 mm were used for the evaluation. A 30-mm range of the mandible just distal to ...

Fig. 2. a Radiographic image of a 3.5-mm-wide by 7...

Fig. 2. a Radiographic image of a 3.5-mm-wide by 7-mm-length dental implant at the time of its placement at the mandibular left second premolar in a 63-year-old Caucasian female. b Radiographic image of a three-unit fixed partial denture upon its initial placement. The dental implant is the anterior abutment with the prosthesis screw retained to it. The distal abutment is the mandibular left sec...

Fig. 1. a Initial radiograph exposed at abutment i...

Fig. 1. a Initial radiograph exposed at abutment installation on a 5-mm-wide by 7-mm-length dental implant used to help support a removable partial denture for a 71-year-old Caucasian male. b Radiograph of the area taken at 82 months demonstrates good bone stability. c Clinical image of the area 82 months later. Soft tissue remains healthy. The two teeth anterior are in the process of receivin...

Table 5 Resonance frequency analysis : A 1–7 ye...

Time ISQ n Implant insertion 73.6 ± 8.1 86 1–4 weeks ...

Table 4 Implant survival, life table analysis : A ...

Interval Implants Failed Not followed CSR (%) Insertion to 1 year ...

Table 3 Specification of failed implants (three im...

Sex Age Smoker Risk factors Position Implant diameter ...

Table 2 Implant and site-related specifications : ...

  Number Percent Jaw Maxilla 60 69.8 Mandible ...

Table 1 Patient demographics : A 1–7 year retro...

  Number Percent Age (years) 20–29 1 1.3 30–39 ...

About this article : A 1–7 year retrospective f...

Rosen, P.S., Sahlin, H., Seemann, R. et al. A 1–7 year retrospective follow-up on consecutively placed 7-mm-long dental implants with an electrowetted surface. Int J Implant Dent 4, 24 (2018). https://doi.org/10.1186/s40729-018-0136-4 Download citation Received: 08 January 2018 Accepted: 21 May 2018 Published: 23 August 2018 DOI: https://doi.org/10.1186/s40729-018-0136...

Rights and permissions : A 1–7 year retrospecti...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : A 1–7 year retrospective ...

The study was performed in compliance with the Declaration of Helsinki. Data collection was performed in such a manner that subjects could not be identified, and therefore, it was exempt from IRB review according to Federal Regulation 45 CFR 46.101(b). All participants consented to publish their information details through the clinic’s standard patient consent procedure. Also, all images appear...

Author information : A 1–7 year retrospective f...

Clinical Professor of Periodontics, Baltimore College of Dental Surgery, University of Maryland Dental School, Baltimore, MD, USA Paul S. Rosen Private Practice limited to Periodontics and Dental Implants, 907 Floral Vale Boulevard, Yardley, PA, 19067, USA Paul S. Rosen Neoss Ltd, Gothenburg, Sweden Herman Sahlin University Clinic of Craniofacial, Maxillofacial and Oral Surgery, Vienna, Aust...

Availability of data and materials : A 1–7 year...

Due to the ethical and legal responsibility to respect participants’ rights to privacy and to protect their identity, the clinical dataset is not made publicly available.

References : A 1–7 year retrospective follow-up...

Srinivasan M, Vazquez L, Rieder P, Moraguez O, Bernard JP, Belser UC. Survival rates of short (6 mm) micro-rough surface implants: a review of literature and meta-analysis. Clin Oral Implants Res. 2014;25(5):539–45. Chrcanovic BR, Albrektsson T, Wennerberg A. Diabetes and oral implant failure: a systematic review. J Dent Res. 2014;93(9):859–67. Giro G, Chambrone L, Goldstein A, Rodrigues JA,...

References : A 1–7 year retrospective follow-up...

Jemt T, Olsson M, Franke SV. Incidence of first implant failure: a retroprospective study of 27 years of implant operations at one specialist clinic. Clin Implant Dent Relat Res. 2015;17(Suppl 2):e501–10. Pommer B, Frantal S, Willer J, Posch M, Watzek G, Tepper G. Impact of dental implant length on early failure rates: a meta-analysis of observational studies. J Clin Periodontol. 2011;38(9):856...

Abbreviations : A 1–7 year retrospective follow...

Cumulative survival rate Implant stability quotient Insertion torque Odds ratio Resonance frequency analysis Relative risk

Conclusion : A 1–7 year retrospective follow-up...

The current retrospective consecutive case series study provides preliminary data that treatment with 7-mm-length short implants with a hydrophilic electrowetted surface is a reasonable approach in sites with limited vertical bone dimension. It adds to the body of evidence supporting short implant use for compromised sites. The success seen might be attributed to the larger implant diameters that ...

Discussion : A 1–7 year retrospective follow-up...

Thirty-six percent of the implants in the study were placed in extraction sockets. Provided that sufficient initial implant stability is achieved, there should be no additional risk factors compared to implants in healed sites. Studies have shown no difference in marginal bone remodeling between immediately placed and delayed implants [15]. The biggest limitation of the current study is its very ...

Discussion : A 1–7 year retrospective follow-up...

A wide distribution in implant insertion torque (10–50 Ncm) was seen in the study. This reflects the variety of clinical situations in which the implants were placed. Assessments were made by using both the RFA value and the insertion torque as to first whether an implant should have been left to heal in the first place and if so, how this would be best accomplished, i.e., through its submergen...

Discussion : A 1–7 year retrospective follow-up...

This retrospective study is the first to look at short dental implants with a hydrophilic electrowetted surface. The survival data suggest that this treatment is a viable option to care. In a systematic review that identified 13 studies on implants shorter than 10 mm, the CSR from the individual studies ranged from 80 to 100% with a combined CSR of 98.3% after 5 years, 94.8% after 6 years, and ...

Results : A 1–7 year retrospective follow-up on...

The chart review identified 86 placed implants in 75 patients. Table 1 summarizes the patient demographics of the 75 patients. Patients ranged in age from 29 to 88 years with a mean of 61.0 ± 12.5 years. Twenty-seven of the patients were males and 48 were females. Table 2 summarizes the implant and site-related information of the 86 placed implants. Mean insertion torque was 30.1 ± 7...

Methods : A 1–7 year retrospective follow-up on...

Baseline parameters, both patient- and implant-related, as well as follow-up parameters (implant survival, follow-up time, and resonance frequency analysis) were collected from a review of the patient records. The main study parameters (principal outcome parameters) were defined to be implant loss and follow-up time. The cumulative survival rate was estimated. The influence of several factors on ...

Methods : A 1–7 year retrospective follow-up on...

A retrospective study on short 7 mm hydrophilic implants from a single center was conducted in a private practice limited to periodontics and surgical dental implant placements from one of the authors, PSR (Yardley, Pennsylvania, USA). An exhaustive chart review identified 75 patients for analysis that were treated with 86 short (7 mm) implants during a 5-year period (September 1, 2009, to Novem...

Background : A 1–7 year retrospective follow-up...

The aim of this retrospective consecutive case series study was to investigate implant survival rate and analyze possible factors affecting the survival of short implants placed in one surgical practice focused on implantology and periodontology in a temporal cohort.

Background : A 1–7 year retrospective follow-up...

In the past decades, the osseointegration rate of dental implants has dramatically increased, particularly in sites of softer dental bone, which may be attributed to the introduction of moderately roughened surfaces [1, 2]. Moreover, because of this increase in success, clinicians have attempted to push the envelope and place implants into sites that may provide a greater challenge as they wish to...

Abstract : A 1–7 year retrospective follow-up o...

This retrospective consecutive case series study was performed to determinate the survival rate and implant stability of short (7 mm length) dental implants with an electrowetted hydrophilic surface that were in function from 1 to 7 years. A retrospective chart review identified and evaluated 86 consecutively placed 7-mm-long dental implants (ProActive, Neoss Ltd., Harrogate, England) in 75 pat...

Fig. 3. One possible missing category (depicted as...

Fig. 3. One possible missing category (depicted as “X”) would be a bone type with thick cortical layer and sparse trabecular bone, which would have intermediate characteristics and behavior between the types with thick (2) or thin (3) cortical bones Fig. 3. One possible missing category (depicted as “X”) would be a bone type with thick cortical layer and sparse trabecular bone, which ...

Fig. 2. Preoperative CT image showing the site for...

Fig. 2. Preoperative CT image showing the site for the definition of the ROI (simulated area delimited by a yellow dashed line for illustration purpose) in the axial (a), coronal (b), and sagittal (6 × 6 mm) (c) sections Fig. 2. Preoperative CT image showing the site for the definition of the ROI (simulated area delimited by a yellow dashed line for illustration purpose) in the axial (...

Fig. 1. Clinical case of a short implant (4.1 ×...

Fig. 1. Clinical case of a short implant (4.1 × 6 mm) placed in the region of the left maxillary first molar. a Implant installed. b Insertion torque measurement using the manual torque wrench. c Implant with healing cap and flap suture. d Immediate periapical radiograph after surgery Fig. 1. Clinical case of a short implant (4.1 × 6 mm) placed in the region of the left maxillar...

Table 3 Comparison of CT mean gray values (average...

Variable Meana Std error 95% confidence interval P value (F; DF) Arch    

Table 2 Matrix of Spearman correlation coefficient...

Variables Torque Tactile CT visual MGV_avg MGV_axial M...

Table 1 Descriptive statistics of the sample : Rel...

Variable Frequency Mean SD 95% confidence interval Patient ...

About this article : Relation between insertion to...

Triches, D.F., Alonso, F.R., Mezzomo, L.A. et al. Relation between insertion torque and tactile, visual, and rescaled gray value measures of bone quality: a cross-sectional clinical study with short implants. Int J Implant Dent 5, 9 (2019). https://doi.org/10.1186/s40729-019-0158-6 Download citation Received: 07 October 2018 Accepted: 06 January 2019 Published: 11 February...

Rights and permissions : Relation between insertio...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Relation between insertion t...

This study was conducted in accordance with the tenets of the Declaration of Helsinki, and all procedures involving human subjects were approved by the ethics committee of the Pontifical Catholic University of Rio Grande do Sul/UBEA (ethical approval letter OF.CEP-772/10; research protocol CEP 10/05074). Written informed consent was obtained from all study participants. Diego Fernandes Triches, ...

Author information : Relation between insertion to...

All authors (1) made substantial contributions to the conception and/or design of the work or the acquisition, analysis, or interpretation of data for the work; (2) drafted the paper or revised it critically; (3) approved the final version of this manuscript; and (4) agreed to be accountable for all aspects of the work. Categories of authors’ contribution are as follows: concept/design (RSS, DFT...

Author information : Relation between insertion to...

Postgraduate Program in Dentistry, Pontifical Catholic University of Rio Grande do Sul (PUCRS), Dental School, Avenida Ipiranga, 6681 – Prédio 6, Porto Alegre, RS, 90619-900, Brazil Diego Fernandes Triches, Fernando Rizzo Alonso, Danilo Renato Schneider, Eduardo Aydos Villarinho, Maria Ivete Rockenbach, Eduardo Rolim Teixeira & Rosemary Sadami Shinkai Postgraduate Program in Dentistry,...

Acknowledgements : Relation between insertion torq...

The authors would like to thank Professor Helena de Oliveira and Dr. Geisa Medeiros for their early assistance with CT software. The work was supported by a research grant from Coordination for the Improvement of Higher Education Personnel (CAPES, Brazil; PNPD grant), the National Counsel of Technological and Scientific Development (CNPq, Brazil; Universal grant), and the International Team for I...

References : Relation between insertion torque and...

Kaya S, Yavuz I, Uysal I, Akkus Z. Measuring bone density in healing periapical lesions by using cone beam computed tomography: a clinical investigation. J Endod. 2012;38:28–31. Brosh T, Yekaterina BE, Pilo R, Shpack N, Geron S. Can cone beam CT predict the hardness of interradicular cortical bone? Head Face Med. 2014;10:12. Tatli U, Salimov F, Kürkcü M, Akoğlan M, Kurtoğlu C. Does cone be...

References : Relation between insertion torque and...

Nomura Y, Watanabe H, Honda E, Kurabayashi T. Reliability of voxel values from cone-beam computed tomography for dental use in evaluating bone mineral density. Clin Oral Implants Res. 2010;21:558–62. Reeves TE, Mah P, McDavid WD. Deriving Hounsfield units using gray levels in cone beam CT: a clinical application. Dentomaxillofac Radiol. 2012;41:500–8. Cassetta M, Stefanelli LV, Pacifici A, P...

References : Relation between insertion torque and...

Degidi M, Daprile G, Piattelli A. Determination of primary stability: a comparison of the surgeon’s perception and objective measurements. Int J Oral Maxillofac Implants. 2010;25:558–61. Alonso FR, Triches DF, Mezzomo LAM, Teixeira ER, Shinkai RSA. Primary and secondary stability of single short implants. J Craniofac Surg. 2018. https://doi.org/10.1097/SCS.0000000000004567. Ribeiro-Rotta RF,...

Abbreviations : Relation between insertion torque ...

Cone beam computed tomography Computed tomographic Digital Imaging and Communications in Medicine Field of view Mean gray values Region of interest

Conclusions : Relation between insertion torque an...

In summary, within the conditions and limitations of this study, the results suggest that bone quality has a significant effect on the primary stability of short implants as measured by insertion torque. Insertion torque had significant correlation with all assessment methods of bone quality. For preoperative CT evaluation of bone quality, mean gray values (optical density) had stronger associatio...

Discussion : Relation between insertion torque and...

The present study also used the same preoperative CT images for visual evaluation of bone quality at the exact implant site, using the axial, coronal, and sagittal sections in a standardized procedure. There was a fairly moderate correlation between CT visual assessment and mean gray values, but no statistical difference was found in average mean gray values between the visual classification of bo...

Discussion : Relation between insertion torque and...

In this study, low- and medium-density values (air and a central FOV soft tissue) were used as reference calibration points for image normalization. The use of a reference object in the FOV containing at least two materials of known density could allow for a calibration similar to the use of reference phantoms in quantitative CT, rather than the “standard” automatic normalization function avai...

Discussion : Relation between insertion torque and...

This study showed that low bone quality, as assessed by clinical and image methods, is related with low primary stability of 6-mm short implants placed at the posterior region of the maxilla and mandible. Higher insertion torque values were associated with better bone types and higher mean gray values in CT images. Insertion torque had a negative moderate association with bone type categorization ...

Results : Relation between insertion torque and ta...

Descriptive statistics of the sample are shown in Table 1. For statistical analysis, some data were missing: one implant had mobility after surgery and was lost and four CT scans, containing 11 ROIs, were not used for bone quality analysis due to technical problems. As only one case was categorized as bone type 1 by CT visual or by tactile evaluation, the corresponding mean gray values were exclu...

Methods : Relation between insertion torque and ta...

The mean gray value of each rescaled ROI was measured on the three orthogonal planes: axial, coronal, and sagittal, totaling three ROIs per implant site. The average of the rescaled gray values for the three ROIs was computed for each implant site. Data were analyzed by descriptive and inferential statistics using the software XLSTAT version 2018 (Addinsoft SARL, New York, USA), and a two-tailed ...

Methods : Relation between insertion torque and ta...

Axial ROI: Using the reference implant location line, the ROI was defined as the alveolar bone area with a 6-mm width corresponding to 3 mm on each side of the future implant center, including the buccal and lingual cortical layers. Coronal ROI: Area defined by the outer border of the cortical bone with a 6-mm height and a line joining the buccal and lingual cortical layers. Sagittal ROI: A 6...

Methods : Relation between insertion torque and ta...

The insertion torque was measured using the manual torque wrench (Straumann Dental Implant System®, Waldenburg, Switzerland) (Fig. 1b), according to three categories:  35 N cm. A healing cap was installed, and the suture was made with nylon 5-0 (Fig. 1c). The patients were prescribed with antibiotics (amoxicillin 500 mg, 8/8 h for 7 days), anti-inflammatory drugs (nimesulide 100 mg,...

Methods : Relation between insertion torque and ta...

This study reports cross-sectional, correlational data of a prospective clinical research project [2] approved by the university Institutional Review Board (10/05074). The research protocol followed the precepts of the Declaration of Helsinki and its amendments. All patients signed an informed consent form. A consecutive, non-probabilistic sample consisted of 45 implants placed in 20 patients tre...

Background : Relation between insertion torque and...

Both multislice CT and cone beam CT are used for presurgical assessment of bone density and quality [4,5,6,7,8,9,10,11]. There is a strong correlation between gray values in cone beam CT and Hounsfield units in multislice CT [4, 12,13,14]. The visual inspection of CT sections avoids the superimposition of anatomical structures seen in radiographs; thus, the region of interest in trabecular bone ca...

Background : Relation between insertion torque and...

The early clinical success of short implants can be affected by poor bone quality and low primary stability because implant micromovement can promote the formation of a fibrous capsule during the osseointegration process. It has been reported that the greater the insertion torque, the greater the resistance of the bone-implant interface to the shear forces that tend to rotate the implant [1]. Clin...

Abstract : Relation between insertion torque and t...

This study assessed the relationship between insertion torque and bone quality evaluated during surgery and in preoperative computed tomographic (CT) images analyzed either visually or by rescaled mean gray values (MGVs). The study also tested the correlation between the clinical and radiographic measures of bone quality. The consecutive sample was composed of 45 short implants (4.1 × 6 mm...

Fig. 6. Forest plot on differences in implant mean...

Fig. 6. Forest plot on differences in implant mean marginal bone loss between MS and RS groups in alle included RCT's Fig. 6. Forest plot on differences in implant mean marginal bone loss between MS and RS groups in alle included RCT's

Fig. 5. Forest plot on differences in implant surv...

Fig. 5. Forest plot on differences in implant survival between MS and RS groups in all included RCT's Fig. 5. Forest plot on differences in implant survival between MS and RS groups in all included RCT's

Fig. 4. Forest plot on differences in implant mean...

Fig. 4. Forest plot on differences in implant mean marginal bone loss between MS and RS groups in all included studies Fig. 4. Forest plot on differences in implant mean marginal bone loss between MS and RS groups in all included studies

Fig. 3. Forest plot on differences in implant surv...

Fig. 3. Forest plot on differences in implant survival between MS and RS groups in all included studies Fig. 3. Forest plot on differences in implant survival between MS and RS groups in all included studies

Fig. 2. a Presentation of risk of bias evaluation ...

Fig. 2. a Presentation of risk of bias evaluation for included RCTs according to the Cochrane Collaboration’s tool. b Presentation of risk of bias evaluation for included non-RCTs according to the Newcastle-Ottawa assessment scale Fig. 2. a Presentation of risk of bias evaluation for included RCTs according to the Cochrane Collaboration’s tool. b Presentation of risk of bias evaluation fo...

Fig. 1. Flowchart of the search strategy : Effect ...

Fig. 1. Flowchart of the search strategy Fig. 1. Flowchart of the search strategy

Table 1 Study characteristics and individual resul...

Study (first author and year of publication)   Design General health Perio health Perio status ...

About this article : Effect of dental implant surf...

Dank, A., Aartman, I.H.A., Wismeijer, D. et al. Effect of dental implant surface roughness in patients with a history of periodontal disease: a systematic review and meta-analysis. Int J Implant Dent 5, 12 (2019). https://doi.org/10.1186/s40729-019-0156-8 Download citation Received: 14 August 2018 Accepted: 06 January 2019 Published: 13 February 2019 DOI: https://doi.org/...

Rights and permissions : Effect of dental implant ...

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Additional files : Effect of dental implant surfac...

Conflict of interest form (PDF 569 kb) Conflict of interest form (PDF 1224 kb) Conflict of interest form (PDF 569 kb) Conflict of interest form (PDF 569 kb)

Ethics declarations : Effect of dental implant sur...

Not applicable. All authors read and approved the final manuscript. Anton Dank, Irene H.A. Aartman, Daniël Wismeijer, and Ali Tahmaseb declare that they have no competing interests (Additional files 1, 2, 3 and 4). Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Effect of dental implant surf...

Section of Oral Implantology and Prosthetic Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands Anton Dank, Daniël Wismeijer & Ali Tahmaseb Department of Social Dentistry, Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Ams...

Acknowledgements : Effect of dental implant surfac...

The authors would like to thank Dr. Elena Nicu for providing missing information about her study. None. This paper is distributed under the terms of the Creative Commons Attribution 4.0 International License, which permits unrestricted use, distribution, and reproduction in any medium, provided the author gives appropriate credit to the original author(s) and the source, provide a link to the Cr...

References : Effect of dental implant surface roug...

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Wennström JL, Ekestubbe A, Gröndahl K, Karlsson S, Lindhe J. Oral rehabilitation with implant-supported fixed partial dentures in periodontitis-susceptible subjects. J Clin Periodontol. 2004;31:713–24. Matarasso S, Rasperini G, Siciliano V, Salvi GE, Lang NP, Aglietta M. A 10-year retrospective analysis of radiographic bone-level changes of implants supporting single-unit crowns in periodonta...

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Kumar A, Jaffin RA, Berman C. The effect of smoking on achieving osseointegration of surface-modified implants: a clinical report. Int J Oral Maxillofac Implants. 2002;17:816–9. Albouy JP, Abrahamsson I, Persson LG, Berghlundh T. Spontaneous progression of peri-implantitis of different types of implants: an experimental study in dogs. I: clinical and radiographic observations. Clin Oral Implant...

References : Effect of dental implant surface roug...

Rosenberg ES, Dent HD, Cho S, Elian N, Jalbout ZN, Froum S. A comparison of characteristics of implant failure and survival in periodontally compromised and periodontally healthy patients: a clinical report. Int J Oral Maxillofac Implants. 2004;19:873–9. Balshe AA, Eckert SE, Koka S, Assad DA, Weaver AL. The effects of smoking on the survival of smooth- and rough-surface dental implants. Int J ...

References : Effect of dental implant surface roug...

Quirynen M, Abarca M, Van Assche N, Nevins M, Van Steenberghe D. Impact of supportive periodontal therapy and implant surface roughness on implant outcome in patients with a history of periodontitis. J Clin Periodontol. 2007;34:805–15. Albrektsson T, Wennerberg A. Oral implant surfaces: part 1–review focusing on topographic and chemical properties of different surfaces and in vivo responses t...

Abbreviations : Effect of dental implant surface r...

Acid-etched Anterior Fixed partial denture Fully edentulous Hydroxyl apatite Hybrid surface Mandible Maxilla Machined surface No data Not reported Non-smoking Partially edentulous Periodontally compromised patient Periodontally healthy patient Posterior Prospective Retrospective Rough surface Smoking Sandblasted acid-etched Titanium plasma sprayed

Conclusions : Effect of dental implant surface rou...

Due to lack of long-term data (> 5 years), the heterogeneity and variability in study designs and lack of reporting on confounding factors, definitive conclusions on differences in implant survival, and mean marginal bone loss between machined and moderate rough implants in periodontally compromised patients cannot be drawn. In order to understand whether or not machined surfaces are superior to...

Discussion : Effect of dental implant surface roug...

The heterogeneity and the variability in the study designs, together with the fact that most previous studies have not reported on confounding factors, make it difficult to draw definitive conclusions. In addition, the broad confidence intervals provide an uncertain outcome. In spite of their relatively higher failure rate, machined implants have possible advantages on the long term, because they ...

Discussion : Effect of dental implant surface roug...

Bias is present in the included papers, and this can have a substantial impact on our findings. For example, in the studies by Wennström et al. and Nicu et al., smoking is a confounding factor, since both non-smokers and smokers have been combined [38, 40]. However, Cavalcanti et al. have performed a retrospective multicenter cohort study and have demonstrated almost twice as many implant failure...

Discussion : Effect of dental implant surface roug...

The current study reviews the literature on the effect of dental implant surfaces in patients with a history of periodontal disease. The six included papers comprised both retrospective and prospective studies [36,37,38,39,40,41]. The two prospective randomized clinical trials were analyzed separately [38, 40]. As demonstrated by equality of the risk ratios and on account of the limited amount of ...

Results : Effect of dental implant surface roughne...

Figure 3 illustrates a forest plot showing no significant differences in implant survival between MS and RS groups in all included studies [36,37,38,39,40,41]. The implant mean marginal bone loss in the remaining group of six included studies containing 1342 implants ranged from 0.33 to 3.77 mm, with a minimum and maximum of − 0.74 and 5.20 mm, respectively [36,37,38,39,40,41]. The forest ...

Results : Effect of dental implant surface roughne...

There is some variation in the follow-up between the different studies. Two studies had a follow-up of 5 years (Sayardoust et al. and Wennström et al.), two had a follow-up of 10 years (Aglietta et al. and Matarasso et al.), and for two studies, it was 3 years (Nicu et al. and Gallego et al.) [36,37,38,39,40,41]. All included periodontally compromised patients participated in a regular periodo...

Results : Effect of dental implant surface roughne...

The initial electronic database search on PubMed/MEDLINE and Cochrane library resulted in 2411 titles. Thirteen articles were cited in both databases (duplicates). After screening the abstracts, 45 relevant titles were selected by two independent reviewers and 2353 were excluded for not being related to the topic. Following examination and discussion by the reviewers, 43 articles were selected for...

Methods : Effect of dental implant surface roughne...

Two reviewers independently extracted data from the included studies. Disagreements were again resolved through discussion. Corresponding authors were contacted when data were incomplete or unclear. With respect to the listed PICO question, data were sought for (P) periodontally compromised and patients without a history of periodontitis receiving dental implant placement, (I) machined surface den...

Methods : Effect of dental implant surface roughne...

This study followed the PRISMA statement guidelines and is registered at PROSPERO under registration code CRD42018093063. A review protocol does not exist. The listed PICO question is used in the present systematic search strategy. The electronic data resources consulted were PubMed/MEDLINE and Cochrane Library, including all published clinical studies until May 2018. The results were limited to ...

Background : Effect of dental implant surface roug...

Several animal studies have suggested that the roughness of the implant surface influences the progression of peri-implantitis and the outcome of peri-implantitis treatment [27,28,29,30,31]. There is some evidence in men showing that machined implants are less prone to peri-implantitis compared with implants with rougher surfaces [32]. Moreover, implants with a rough surface have higher rates of l...

Background : Effect of dental implant surface roug...

Rough titanium implants are currently the standard treatment in implant dentistry [1]. They are roughly divided into three different types of surface roughness (Sa): machined/minimal (± 0.5 μm), moderate (1.0–2.0 μm), and rough (> 2.0 μm) [2]. Generally, rougher implant surfaces have greater bone-to-implant contact [3]. In a randomized controlled clinical trial, it has been demonstra...

Abstract : Effect of dental implant surface roughn...

To review the literature on the effect of dental implant surface roughness in patients with a history of periodontal disease. The present review addresses the following focus question: Is there a difference for implant survival, mean marginal bone loss, and the incidence of bleeding on probing in periodontally compromised patients receiving a machined dental implant or rough surface dental implant...

Table 5 Implant failure rates : Mucositis, peri-im...

  Failure rate n Univariate analyses Multivariate analyses OR (95% CI) P OR ...

Table 4 Risk factors for peri-implantitis : Mucosi...

  Peri-implantitis n Univariate analyses Multivariate analyses   OR (95% CI) P ...

Table 3 Risk factors for mucositis : Mucositis, pe...

  Mucositis n Univariate analyses Multivariate analyses OR (95% CI) P OR ...

Table 2 Observation period (patient and implant re...

Years Patients (total) GCP patients GAP patients Implants (total) Implants maxilla ...

Table 1 Implants in study population : Mucositis, ...

  GCP GAP Patient 24 5 Sex ...

About this article : Mucositis, peri-implantitis, ...

Mengel, R., Heim, T. & Thöne-Mühling, M. Mucositis, peri-implantitis, and survival and success rates of oxide-coated implants in patients treated for periodontitis 3- to 6-year results of a case-series study. Int J Implant Dent 3, 48 (2017). https://doi.org/10.1186/s40729-017-0110-6 Download citation Received: 29 August 2017 Accepted: 26 October 2017 Published: 28 Novemb...

Rights and permissions : Mucositis, peri-implantit...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Mucositis, peri-implantitis,...

RM is a professor at the Department of Prosthetic Dentistry, School of Dental Medicine, Philipps-University, Marburg/Lahn, Germany. TH is a private practicioner in Gruben, Brandenburg, Germany. MT is a researcher at the Department of Prosthetic Dentistry, School of Dental Medicine, Philipps-University, Marburg/Lahn, Germany. This clinical study was conducted in accordance with the World Medical A...

Author information : Mucositis, peri-implantitis, ...

Department of Prosthetic Dentistry, School of Dental Medicine, Philipps-University, Marburg/Lahn, Germany Reiner Mengel & Miriam Thöne-Mühling Gruben, Brandenburg, Germany Theresa Heim You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar You can also search for this au...

References : Mucositis, peri-implantitis, and surv...

Kim K-K, Sung H-M. Outcomes of dental implant treatment in patients with generalized aggressive periodontitis: a systematic review. J Adv Prosthodont. 2012;4:210–7. Pettersson K, Mengel R. Comments on the statistical analysis of the paper by Albouy et al comparing four different types of implants with respect to ‘spontaneous’ progression of peri-implantitis. Eur J Oral Implantol. 2011;1:9...

References : Mucositis, peri-implantitis, and surv...

Kinane DF, Radvar M. The effect of smoking on mechanical and antimicrobial periodontal therapy. J Periodontol. 1997;69:467–72. Swierkot K, Lottholz P, Flores-de-Jacoby L, Mengel R. Mucositis, peri-implantitis, implant success, and survival of implants in patients with treated generalized aggressive periodontitis: 3- to 16-year results of a prospective long-term cohort study. J Periodontol. 2012...

References : Mucositis, peri-implantitis, and surv...

Jungner M, Lundqvist P, Lundgren S. A retrospective comparison of oxidized and turned implants with respect to implant survival, marginal bone level and peri-implant soft tissue conditions after at least 5 years in function. Clin Implant Dent Relat Res. 2014;16:230–7. Rocci A, Rocci M, Rocci C, Scoccia A, Gargari M, Martignoni M, Gottlow J, Sennerby L. Immediate loading of Brånemark system TiU...

References : Mucositis, peri-implantitis, and surv...

Esposito M, Ardebili Y, Worthington HV. Interventions for replacing missing teeth: different types of dental implants. Cochrane Database Sys Rev. 2014;7:CD003815. Salata LA, Burgos PM, Rasmusson L, Novaes AB, Papalexiou V, Dahlin C, Sennerby L. Osseointegration of oxidized and turned implants in circumferential bone defects with and without adjunctive therapies: an experimental study on BMP-2 and...

Conclusions : Mucositis, peri-implantitis, and sur...

The results of the present case series study should be interpreted in a critical light because of the small study population. However, it can be concluded that periodontally diseased subjects treated in a supportive periodontal therapy can be successfully rehabilitated with oxide-coated dental implants for a follow-up period of 3 to 6 years. The results suggest that implants in the maxilla and in...

Discussion : Mucositis, peri-implantitis, and surv...

These results from long-term clinical studies indicate that oxide-coated implants achieve equivalent survival rates and prevalence of mucositis and peri-implantitis when compared to implants with other surface characteristics. They support the assumption that the implant surface has little influence on the development of mucositis or peri-implantitis. This was subsequently confirmed in a Cochrane ...

Discussion : Mucositis, peri-implantitis, and surv...

The present study examines the success rates of oxide-coated implants in subjects with treated periodontal disease. Several long-term clinical studies on periodontally healthy subjects have revealed survival rates of 97.1 to 99.2% for oxide-coated implants [10, 24, 25]. The results of the present study show a comparable implant survival rate (96.2% in GAP and 97.1% in GCP subjects) for subjects wi...

Results : Mucositis, peri-implantitis, and surviva...

The univariate analyses showed a significantly higher risk for peri-implantitis in GAP subjects (OR = 3.294 with p = 0.027) and at implants with bone quality grade 3 (OR = 21.200 with p = 0.000). However, these differences were not significant in multivariate analyses. Both the uni- and multivariate patient-related analyses were non-significant. The implant success rate was 77.9% for GCP...

Results : Mucositis, peri-implantitis, and surviva...

All 29 subjects were examined over the period of 3 to 6 years (Table 2). For the duration of the observation period, all the remaining teeth were periodontally healthy, with PDs ≤ 3 mm and negative BOP. All subjects were non-smokers, had excellent oral hygiene, attended the follow-up examinations on a regular basis, and had no systemic disease. In total, four implants (3.1%) were lost du...

Materials and methods : Mucositis, peri-implantiti...

Peri-implant mucositis was defined as PDs ≥ 5 mm with BOP and no bone loss after the first year of loading. Peri-implantitis was defined as PDs > 5 mm with or without BOP and an annual bone loss of > 0.2 mm after the first year of loading. All technical and surgical complications (e.g., fracture of the abutment screw or superstructure, compromised wound healing) were recorded. T...

Materials and methods : Mucositis, peri-implantiti...

All patients received a supportive periodontal therapy at the Dental School of Medicine, Philipps-University, Marburg, in the course of the observation period. The first clinical examination was 2 to 4 weeks before the non-retainable teeth were extracted. The periodontally healthy residual dentition and the implants were evaluated immediately after the superstructure was inserted. Subsequently, t...

Materials and methods : Mucositis, peri-implantiti...

Second-stage surgery was performed in the maxilla after 6 months and in the mandible after 3 months. Implant placement and second-stage surgery were performed by a single periodontist (R.M.). About 4 weeks after the final abutments were placed, GCP subjects were rehabilitated with single crowns, implant-supported bridges, or removable superstructures, according to the Marburg double crown syst...

Materials and methods : Mucositis, peri-implantiti...

A total of 29 partially edentulous subjects were consecutively recruited from the Dental School of Medicine, Philipps-University, Marburg, Germany between April 2010 and April 2013 (Table 1). Subjects were excluded for the following reasons: history of systemic disease (e.g., cardiovascular diseases, diabetes mellitus, osteoporosis), pregnancy, untreated caries, current orthodontic treatment, con...

Background : Mucositis, peri-implantitis, and surv...

The aim of this long-term clinical study on partially edentulous subjects treated for periodontal disease was to evaluate the prevalence of mucositis and peri-implantitis and to determine the survival and success rates of dental implants with oxide-coated surfaces.

Background : Mucositis, peri-implantitis, and surv...

In recent years, a great number of different implant systems varying in materials, surface structure, and macroscopic design have been introduced to the dental market [1]. In studies using implants with modified surfaces, it was concluded that rough surfaces induce a stronger initial bone response, achieve stability more rapidly, and integrate more fully with extant bone [2,3,4,5,6]. Dental implan...

Abstract : Mucositis, peri-implantitis, and surviv...

The aim of this case-series study is to evaluate the prevalence of mucositis, peri-implantitis, and survival and success rates of oxide-coated implants in subjects treated for periodontitis. Twenty-four subjects treated for generalized chronic periodontitis (GCP) and five treated for generalized aggressive periodontitis (GAP) were orally rehabilitated with a total of 130 dental implants. Subjects...

Fig. 1. Anatomical location of the control and Ca...

Fig. 1. Anatomical location of the control and Ca2+-modified dental implants Fig. 1. Anatomical location of the control and Ca2+-modified dental implants

Table 3 Outcomes of experimental and control group...

Variable Experimental Control P 

Table 2 Length and diameter of the dental implants...

  Diameter (mm) Total 4.25 5.00 5.50 6.00 6.25 ...

Table 1 Length and diameter of the dental implants...

  Diameter (mm) Total 4.25 5.00 5.50 6.00 6.25 ...

About this article : Early marginal bone stability...

Anitua, E., Piñas, L. & Alkhraisat, M.H. Early marginal bone stability of dental implants placed in a transalveolarly augmented maxillary sinus: a controlled retrospective study of surface modification with calcium ions. Int J Implant Dent 3, 49 (2017). https://doi.org/10.1186/s40729-017-0111-5 Download citation Received: 04 September 2017 Accepted: 15 November 2017 Publi...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were...

Ethics declarations : Early marginal bone stabilit...

An exemption from IRB approval of the study protocol was granted by the author’s institution as it was a retrospective study, and the evaluated medical device had already been approved for clinical use. This study was performed following the Helsinki declaration regarding the investigation with human subjects. Not applicable. Eduardo Anitua is the Scientific Director of BTI Biotechnology Insti...

Author information : Early marginal bone stability...

Private practice in oral implantology, Clínica Eduardo Anitua, Vitoria, Spain Eduardo Anitua University Institute for Regenerative Medicine and Oral Implantology - UIRMI (UPV/EHU-Fundación Eduardo Anitua), Vitoria, Spain Eduardo Anitua & Mohammad Hamdan Alkhraisat BTI Biotechnology Institute, Vitoria, Spain Eduardo Anitua & Mohammad Hamdan Alkhraisat Universidad Europea de Madrid, Madr...

Acknowledgements : Early marginal bone stability o...

Not applicable No funding was received for this study. The data will not be shared but are available upon request.

References : Early marginal bone stability of dent...

Schulze R, Krummenauer F, Schalldach F, d'Hoedt B. Precision and accuracy of measurements in digital panoramic radiography. Dentomaxillofac Radiol. 2000;29:52–6. Download references

References : Early marginal bone stability of dent...

Jaffin RA, Berman CL. The excessive loss of Branemark fixtures in type IV bone: a 5-year analysis. J Periodontol. 1991;62:2–4. Anitua E, Alkhraisat MH, Pinas L, Orive G. Efficacy of biologically guided implant site preparation to obtain adequate primary implant stability. Ann Anat. 2015;199:9–15. Anitua E, Alkhraist MH, Piñas L, Orive G. Association of transalveolar sinus floor elevation, p...

References : Early marginal bone stability of dent...

Moraschini V, Poubel LA, Ferreira VF, Barboza Edos S. Evaluation of survival and success rates of dental implants reported in longitudinal studies with a follow-up period of at least 10 years: a systematic review. Int J Oral Maxillofac Surg. 2015;44:377–88. Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 200...

Abbreviations : Early marginal bone stability of d...

Plasma rich in growth factors Strengthening the Reporting of Observational studies in Epidemiology

Conclusions : Early marginal bone stability of den...

The modification of an acid-etched surface with calcium ions (UnicCa®) seems to enhance the marginal bone stability of dental implants, placed after transalveolar sinus floor elevation.

Results and discussion : Early marginal bone stabi...

Unlike Ca2+-modified dental implants, two early implant losses were observed for the same dental implants but without Ca2+. Moderately rough implant surface has enhanced implant osseointegration and has increased the implant secondary stability [2, 3, 19]. Hydrophilic moderately rough surfaces showed faster osseointegration compared to those with hydrophobic characteristics [20, 21]. Ca2+ ions hav...

Results and discussion : Early marginal bone stabi...

In this study, 51 patients participated with 65 dental implants. The mean age of the patients was 58 ± 11 years (range 38 to 72 years) at the time of surgery, and 28 were females. The experimental group had 34 Ca2+-modified dental implants, and the control group had 31 dental implants (without surface modification with calcium ions). Tables 1 and 2 show the diameters and lengths of the p...

Methods : Early marginal bone stability of dental ...

The plasma rich in growth factors (PRGF) was prepared using the Endoret® system following the manufacturer instructions (BTI Biotechnology Institute, Vitoria, Spain). The technique for transalveolar sinus floor elevation is explained elsewhere [15]. Briefly, conventional drills working at low speed (150 rpm) without irrigation was used to prepare the implant site. A frontal cutting drill was the...

Methods : Early marginal bone stability of dental ...

The manuscript was written following STROBE (Strengthening the Reporting of Observational studies in Epidemiology) guidelines. All described data and treatments were obtained from a single dental clinic in Vitoria, Spain. The time period of the study was between December 2014 and April 2016. Patients’ records were retrospectively reviewed to identify patients that fulfilled the following inclusi...

Background : Early marginal bone stability of dent...

Dental implants are nowadays the treatment of choice to replace missing teeth due to their high predictability and long-term success [1]. This success is the outcome of several cellular and molecular events that take place at the implant-bone interface. Although the process of osseointegration is not fully understood, research is ongoing to enhance and accelerate this process. Moderately rough imp...

Abstract : Early marginal bone stability of dental...

Recently, components of the extracellular cellular matrix have been assessed to enhance the biological response to dental implants. This study aims to assess the effect of surface modification with calcium ions on the early marginal bone loss of dental implants placed in a transalveolarly augmented maxillary sinus. A retrospective study of transalveolar sinus floor augmentation was conducted in a...

About this article : The influence of systemically...

Kanazawa, M., Atsuta, I., Ayukawa, Y. et al. The influence of systemically or locally administered mesenchymal stem cells on tissue repair in a rat oral implantation model. Int J Implant Dent 4, 2 (2018). https://doi.org/10.1186/s40729-017-0112-4 Download citation Received: 19 September 2017 Accepted: 04 December 2017 Published: 13 January 2018 DOI: https://doi.org/10.118...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : The influence of systemicall...

Miya Kanazawa, Ikiru Atsuta, Yasunori Ayukawa, Takayoshi Yamaza, Ryosuke Kondo, Yuri Matsuura, and Kiyoshi Koyano declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : The influence of systemically...

Correspondence to Ikiru Atsuta.

Author information : The influence of systemically...

Section of Implant and Rehabilitative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan Miya Kanazawa, Ikiru Atsuta, Yasunori Ayukawa, Ryosuke Kondo, Yuri Matsuura & Kiyoshi Koyano Department of Molecular Cell and Oral Anatomy, Faculty of Dental Science, Kyushu University, Fukuoka, Japan Takayoshi...

Acknowledgements : The influence of systemically o...

This work was supported by JSPS KAKENHI Grant Numbers JP 15H05029 and 15H02573 to Y. Ayukawa.

References : The influence of systemically or loca...

Bazhanov N, Ylostalo JH, Bartosh TJ, Tiblow A, Mohammadipoor A, Foskett A, Prockop DJ. Intraperitoneally infused human mesenchymal stem cells form aggregates with mouse immune cells and attach to peritoneal organs. Stem Cell Res Ther. 2016;7:27. Goldmacher GV, Nasser R, Lee DY, Yigit S, Rosenwasser R, Iacovitti L. Tracking transplanted bone marrow stem cells and their effects in the rat MCAO stro...

References : The influence of systemically or loca...

Stepp MA, Spurr-Michaud S, Tisdale A, Elwell J, Gipson IK. Alpha 6 beta 4 integrin heterodimer is a component of hemidesmosomes. Proc Natl Acad Sci U S A. 1990;87:8970–4. Schroeder A, van der Zypen E, Stich H, Sutter F. The reactions of bone, connective tissue, and epithelium to endosteal implants with titanium-sprayed surfaces. J Maxillofac Surg. 1981;9:15–25. Schroeder HE, Listgarten MA. F...

References : The influence of systemically or loca...

Zhang L, Li K, Liu X, Li D, Luo C, Fu B, Cui S, Zhu F, Zhao RC, Chen X. Repeated systemic administration of human adipose-derived stem cells attenuates overt diabetic nephropathy in rats. Stem Cells Dev. 2013;22:3074–86. Zheng B, von See MP, Yu E, Gunel B, Lu K, Vazin T, Schaffer DV, Goodwill PW, Conolly SM. Quantitative magnetic particle imaging monitors the transplantation, biodistribution, a...

References : The influence of systemically or loca...

Egusa H, Sonoyama W, Nishimura M, Atsuta I, Akiyama K. Stem cells in dentistry—part I: stem cell sources. J Prosthodont Res. 2012;56:151–65. Lindhe J, Berglundh T. The interface between the mucosa and the implant. Periodontol. 1998;17:47–54. Ikeda H, Shiraiwa M, Yamaza T, Yoshinari M, Kido MA, Ayukawa Y, Inoue T, Koyano K, Tanaka T. Difference in penetration of horseradish peroxidase trace...

Conclusions : The influence of systemically or loc...

Our study supports systemic administration of MSCs to enable accelerated soft tissue sealing of the Ti surface in our rat oral implantation model. Although local MSC administration had little positive effect in our model, the MSCs accumulated around the peri-implant oral mucosa and were identified in various organs, indicating a wide range of possible applications. This study highlights that clini...

Results and discussion : The influence of systemic...

Figure 7C and D showed the suitable amount of MSCs had much better positive effect for the migration and adhesion of OECs to titanium surface. MSC attachment within the upper Transwell chamber was determined 24 h after seeding by fluorescence microscopy, as shown in Fig. 7D (a). The majority of MSCs appeared flattened with numerous cytoplasmic extensions and lamellipodia. The majority of MSCs pass...

Results and discussion : The influence of systemic...

Due to the existence of muscles, connective tissue, dermal layer, and basement membrane, cells within the mass of the injected area encounter these barriers, inhibiting the distance of migration between the application region and inflammatory site, which has an estimated diameter of 20–30 μm (Fig. 6). High-density cell injection at the topical region is also an obstacle for homing, thus using a...

Results and discussion : The influence of systemic...

Subcutaneously administrated cells or drugs are reported to take a few days to be delivered into the body through vessel bloods [33, 34]. This may be owed to difficulty of the cells in securing vascular accesses to the target site because of a lack of blood vessels at the buccinators, while systemic MSC homing occurs more readily through the bloodstream [35]. The effects of MSC treatment on level...

Results and discussion : The influence of systemic...

As shown in Fig. 3b, expression of adhesion proteins on the interface between PIE-implant was significantly lower in the control and local groups compared with the systemic group. Ln-332 is the major adhesive ligand for integrin α6β4, which interacts with the cytoskeletal elements, and is a component of the hemidesmosomes, epithelial adhesion plaques that tack the plasma membrane of the epithe...

Results and discussion : The influence of systemic...

Because MSC treatment is being introduced more widely as a clinically available therapy, the method of administration must be considered to better mitigate risk. Although for a number of other factors also need consideration, including cell source, cell donor condition, cell population, and timing of MSC administration, this study only focused on comparison between systemic and local injection of ...

Methods : The influence of systemically or locally...

OEC adhesion assays were conducted according to previously published methods [16, 20]. Non-adherent or weakly attached cells were removed by shaking (3 × 5 min at 75 rpm) using a rotary shaker (NX-20, Nissin, Tokyo, Japan). Adherent cells were then counted and calculated as a percentage of the initial count, which was used to define adhesive strength of the cells. Scratch assays were perfo...

Methods : The influence of systemically or locally...

For apoptosis detection, the 10-μm bucco-palatal sections from around the experimental implant were incubated overnight with FITC-conjugated anti-rat GFP (1:100, Sigma-Aldrich) and 7-amino actinomycin D (7-AAD, Apoptosis Detection Kit; BD Biosciences, Franklin Lakes, NJ) at 4 °C. Apoptotic cells were then counted and calculated as a percentage of the total cells. MSCs were cultured in osteogen...

Methods : The influence of systemically or locally...

Twenty-four hours after implantation, rats were lightly anesthetized with chloral hydrate and lidocaine hydrochloride, and ex vivo expanded P3 green fluorescent protein (GFP)-MSCs (1 × 106 cells) were administrated via one of the following modes: (1) systemic injection via the tail vein (systemic group), (2) local injection into the gingivobuccal fold around the dental implant (local group), ...

Methods : The influence of systemically or locally...

Bone marrow cells were flushed out of the femurs and tibias of 4-week-old green fluorescent protein-transgenic Wistar rats. Cells were treated with a 0.85% NH4Cl solution for 10 min to lyse the red blood cells and were passed through a 70-μm cell strainer to obtain a single cell suspension. Cells were seeded into 100-mm plastic culture dishes (1 × 106 cells/dish), washed with phosphate buff...

Background : The influence of systemically or loca...

The purpose of this study was to verify the effects and mechanisms of bone marrow-derived MSCs following their local administration using an oral implantation rat model, to deepen our understanding of this approach for effective utilization of MSCs.

Background : The influence of systemically or loca...

Mesenchymal stem cell (MSC)-based approaches can be broadly divided into two categories: cell therapy and regenerative medicine. Cell therapy is focused on the anti-inflammatory, immune-regulatory, and homeostasis-regulatory actions of MSCs to treat disorders like malignant lymphoma, angina pectoris, and atopic dermatitis. Conversely, regenerative medicine is focused on MSCs playing a tissue engin...

Abstract : The influence of systemically or locall...

Multipotent mesenchymal stem cells (MSCs) are used clinically in regenerative medicine. Our previous report showed systemically injected MSCs improved peri-implant sealing and accelerated tissue healing. However, the risks of systemic MSC administration, including lung embolism, must be considered; therefore, their local application must be assessed for clinical safety and efficacy. We investigate...

Fig. 1. The frequency of each training standard co...

Fig. 1. The frequency of each training standard covered by CPD courses Fig. 1. The frequency of each training standard covered by CPD courses

Table 5 Selection criteria for NHS dental implant ...

Selection criteria for NHS dental implant therapy 1 People with congenital conditions resulting in deformed and/or missing teeth 2 ...

Table 4 Summary of findings from analysis of CPD c...

Qualification Duration (years) Study mode Mean tuition fee—per course (£) CPD (11 verifiable, 2 non-verifiable) ...

Table 3 Summary of findings from analysis of acade...

Level of qualification Mean duration (years) Study mode Mean tuition fee—per course (£) FT ...

Table 2 List of dental institutions offering postg...

Dental institutions BPP University Cardiff University Edge Hill University Faculty of General Dental Practitioners ...

Table 1 Training standards in FGDP (UK) TSID 2016 ...

Training Standards in Implant Dentistry, 2016 1 Basic sciences: surgical anatomy, pathological process, bone defects, healing processes 2 ...

About this article : Postgraduate education in den...

Kim, N.Y., Stagnell, S. Postgraduate education in dental implantology in the United Kingdom: a review. Int J Implant Dent 4, 8 (2018). https://doi.org/10.1186/s40729-017-0115-1 Download citation Received: 27 August 2017 Accepted: 28 December 2017 Published: 29 January 2018 DOI: https://doi.org/10.1186/s40729-017-0115-1

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Author information : Postgraduate education in den...

Dover Health Centre Dental Department, Maidson Dieu Road, Dover, CT16 1RH, UK Na Yeoun Kim Southampton NHS Treatment Centre, Royal South Hants Hospital, Brinton Terrace, Southampton, Hampshire, SO14 0YG, UK Sami Stagnell You can also search for this author in PubMed Google Scholar You can also search for this author in PubMed Google Scholar ...

Funding : Postgraduate education in dental implant...

Author Na Yeoun Kim and Sami Stagnell state that no funding was received.

References : Postgraduate education in dental impl...

Marketsandmarkets. Dental Implants and Prosthetics Market by Type (Implant, Crown, Bridge, Denture, Abutment, Veneer, Inlay, Onlay), Material (Titanium, Zirconium, Ceramic, Porcelain-Fused-to-Metal), Type of Facility (Hospitals, Dental Laboratories) - Forecast to 2021. Available from: http://www.marketsandmarkets.com/Market-Reports/dental-implants-prosthetics-market-695.html [Accessed 16 April 201...

Abbreviations : Postgraduate education in dental i...

Continuing professional development Faculty of General Dental Practice (United Kingdom) General Dental Council National Health Service Royal College of Surgeons of England Training Standards in Implant Dentistry Universities and Colleges Admissions Services United Kingdom

Conclusion : Postgraduate education in dental impl...

Development of FGDP (UK) TSID guidelines has led to a significant improvement in the quality of postgraduate education in Dental Implantology in the UK. However, not all courses are fully compliant with these guidelines, and the provision of mentoring for implant placements also needs to be standardised. Quality-assured training is directly related to patient safety, and therefore, all UK postgrad...

Review : Postgraduate education in dental implanto...

Teaching experience and formal qualifications of speakers were shown to be the most important criterion for quality assurance of the courses, and it is fundamental that more nationally or internationally accredited courses with quality teaching staff become widely available throughout the country. In addition, all courses should have clear aims and learning objectives as well as formal end-of-cour...

Review : Postgraduate education in dental implanto...

This study revealed the variation that exists amongst the postgraduate academic and CPD courses in Dental Implantology in terms of level of qualification, duration, study mode, tuition fee, entry requirements and core modules. The level of qualification ranged from non-verifiable CPD to masters level, and the duration of courses also varied in accordance with the level of qualifications. Most of t...

Review : Postgraduate education in dental implanto...

Due to the design of the study, the data collection was only based on the information available online or in dental journals. This inevitably carried the risk of the information being outdated or exclusion of further details that were available via other methods. This was particularly relevant when reviewing the core modules of the academic courses identified. A considerable number of courses only...

Review : Postgraduate education in dental implanto...

A total of 13 CPD courses were included in this study. The mean duration for CPD courses was 0.94 years, and all courses were delivered in part-time mode. The mean tuition fee per course was £7543.08. Eleven of these courses were verifiable CPD courses, and two courses were providing certificates only, which would be considered as non-verifiable CPD courses. Of 11 institutions who declared that ...

Review : Postgraduate education in dental implanto...

All the academic courses identified from this process were included in this study, and a total of 18 courses were included in the study. The list of ten dental institutions offering postgraduate academic courses in Dental Implantology is shown in Table 2. There were eight master level courses with three full-time options and five part-time options, and the mean duration of the courses was 2.50 ...

Review : Postgraduate education in dental implanto...

This article aims to evaluate the current standards of the postgraduate education in Dental Implantology in the UK by identifying all postgraduate academic qualifications and CPD courses available in the field of Dental Implantology and comparing their core modules against the FGDP (UK) TSID 2016 guidelines. Completion of specialist training in another field of dentistry, such as oral surgery, pe...

Review : Postgraduate education in dental implanto...

The global dental implants and prosthetics market is expected to reach USD 12.32 billion by 2021, at a compound annual growth rate of 7.2% from 2016 to 2021 [1]. Although Europe accounted for the largest share of the global dental implants and prosthetics market in 2015 [1], the number of implants placed per 10,000 people in the United Kingdom (UK) is significantly lower than many comparable Europ...

Abstract : Postgraduate education in dental implan...

The qualified dentists in the United Kingdom (UK) are not expected to be competent in practising implant dentistry without further training in the subject and there is now greater emphasis on postgraduate training in Dental Implantology. There are three main education pathways at present, yet their training standards vary significantly. This study aims to identify UK postgraduate academic qualifi...

Fig. 5. Bone resorption in the follow-up of the co...

Fig. 5. Bone resorption in the follow-up of the control group and the perforation group Fig. 5. Bone resorption in the follow-up of the control group and the perforation group

Fig. 4. The initial bone level of the control grou...

Fig. 4. The initial bone level of the control group and the perforation group Fig. 4. The initial bone level of the control group and the perforation group

Fig. 3. Reasons for perforations : Impact of surgi...

Fig. 3. Reasons for perforations Fig. 3. Reasons for perforations

Fig. 2. Overview of the perforation treatment in t...

Fig. 2. Overview of the perforation treatment in the study group Fig. 2. Overview of the perforation treatment in the study group

Fig. 1. Bone levels after sinus floor elevation : ...

Fig. 1. Bone levels after sinus floor elevation Fig. 1. Bone levels after sinus floor elevation

Table 6 Fisher’s exact test: incidence of peri-i...

  Peri-implantitis No peri-implantitis Perforation group 12 80 Control group ...

Table 5 Fisher’s exact test: surgical strategy d...

  One-stage procedure Two-stage procedure Perforation group 11 81 Control group ...

Table 4 Multiple comparisons of subgroups: postope...

Adjusted p values multiple comparison Control group bone level  4 mm 0.0453 Control group bone level > ...

Table 3 Data summary of bone level development : I...

  Bone level preoperatively Bone level postoperatively Bone level follow-up Bone resorption Perforation group ...

Table 2 Origin of bone graft : Impact of surgical ...

Origin of bone graft No bone graft Linea obliqua Iliac crest Scapula flap Perforation...

Table 1 Distribution of implant positions : Impact...

Implant position 3 4 5 6 7 8...

About this article : Impact of surgical management...

Beck-Broichsitter, B.E., Westhoff, D., Behrens, E. et al. Impact of surgical management in cases of intraoperative membrane perforation during a sinus lift procedure: a follow-up on bone graft stability and implant success. Int J Implant Dent 4, 6 (2018). https://doi.org/10.1186/s40729-018-0116-8 Download citation Received: 03 October 2017 Accepted: 03 January 2018 Publish...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Impact of surgical managemen...

The authors Benedicta Beck-Broichsitter, Dorothea Westhoff, Eleonore Behrens, Jörg Wiltfang, and Stephan T. Becker declare that there are no existing competing interests concerning this collaborative work. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Impact of surgical management...

Correspondence to Benedicta E. Beck-Broichsitter.

Author information : Impact of surgical management...

Department of Oral and Maxillofacial Surgery, Charité–University Medical Center Berlin, Augustenburger Platz 1, 13353, Berlin, Germany Benedicta E. Beck-Broichsitter Department of Oral and Maxillofacial Surgery, Schleswig-Holstein University Hospital, Arnold-Heller-Straße 3, Haus 26, 24105, Kiel, Germany Dorothea Westhoff, Eleonore Behrens, Jörg Wiltfang & Stephan T. Becker You can al...

Funding : Impact of surgical management in cases o...

This study was not funded.

References : Impact of surgical management in case...

Shlomi B, Horowitz I, Kahn A, Dobriyan A, Chaushu G. The effect of sinus membrane perforation and repair with Lambone on the outcome of maxillary sinus floor augmentation: a radiographic assessment. Int J Oral Maxillofac Implants. 2004;19(4):559–62. Moreno Vazquez JC, Gonzalez de Rivera AS, Gil HS, Mifsut RS. Complication rate in 200 consecutive sinus lift procedures: guidelines for prevention ...

References : Impact of surgical management in case...

Sakkas A, Konstantinidis I, Winter K, Schramm A, Wilde F. Effect of Schneiderian membrane perforation on sinus lift graft outcome using two different donor sites: a retrospective study of 105 maxillary sinus elevation procedures. GMS Interdiscip Plast Reconstr Surg DGPW. 2016;5:Doc11. Springer IN, Terheyden H, Geiss S, Harle F, Hedderich J, Acil Y. Particulated bone grafts—effectiveness of bone...

References : Impact of surgical management in case...

Wiltfang J, Schultze-Mosgau S, Nkenke E, Thorwarth M, Neukam FW, Schlegel KA. Onlay augmentation versus sinuslift procedure in the treatment of the severely resorbed maxilla: a 5-year comparative longitudinal study. Int J Oral Maxillofac Surg. 2005;34(8):885–9. Pikos MA. Maxillary sinus membrane repair: report of a technique for large perforations. Implant Dent. 1999;8(1):29–34. Cha HS, Kim ...

Conclusions : Impact of surgical management in cas...

In conclusion, and within the limits of its retrospective nature, our study implies that in cases of intraoperative perforation of the Schneiderian membrane, a consequent surgical assessment and treatment might avoid complications regarding graft stability and implant survival. Two-stage procedures might be appropriate if primary stability does not seem to be achievable. Augmentation of the sinus ...

Discussion : Impact of surgical management in case...

The surgical management in cases of a membrane perforation might also influence the overall postoperative outcome and complications. Although the sinus lifting procedure has been established for many years now, there are no evidence-based guidelines for perforation closure or indications to interrupt the procedure. To date, most existing studies recommend sealing smaller sizes of perforations with...

Discussion : Impact of surgical management in case...

One implant was lost in the perforation group due to early-onset peri-implantitis, whereas all implants in the control group were still in place. As we had previously prospectively reported on the first 6 months after dental implantation in this cohort [11], there was no further impact of membrane perforation on implant loss for at least 12 to 24 months in this retrospective evaluation. The appe...

Discussion : Impact of surgical management in case...

The aim of this retrospective cohort study was to evaluate the impact of intraoperative perforations of the Schneiderian membrane during sinus floor elevation on the stability of the augmented area and its influence on osseointegration after implant insertion. Therefore, we could re-assess a patient cohort of originally 34 patients with 41 perforations and compare their outcome with a control grou...

Results : Impact of surgical management in cases o...

The initial bone level differed significantly (p = 0.05) between both groups with a median value of 5.69 mm in the study group and 3.87 mm in the control group (Fig. 4). A Mann-Whitney-U-Wilcoxon test revealed no significant difference between bone level postoperatively (p = 0.7851; median value control group 17.40 mm; median value perforation group 16.91 mm), in follow-up (p = 0....

Results : Impact of surgical management in cases o...

The mean control interval was 2.69 (± 2.03) years. At the time of the follow-up examination, the average age was 59.95 (± 11.82) years. In the remaining collective of 31 patients (96.97%; 12 males (37.54%) and 19 females (59.43%)), a total of 92 implants were inserted. The overview of perforation treatment in the study group is given in Fig. 2, and Fig. 3 depicts the reasons for perforati...

Methods : Impact of surgical management in cases o...

One independent oral and maxillofacial surgeon performed the clinical follow-up examinations according to a standardized protocol. A peri-implant probing including probing pocket depths and recessions on four sites of each implant was assessed as was bleeding on probing (BOP) to determine the status of oral hygiene objectively. Signs of gingivitis and pus suppuration were also recorded. The criter...

Methods : Impact of surgical management in cases o...

Three different oral and maxillofacial surgeons performed the sinus lift procedure with an external approach according to comparable surgical standards and inserted all implants examined in this study in a submerged protocol with uncovering after 3–4 months due to the manufacturer’s surgical recommendations. Specifically, a total of 35 external sinus floor elevations were performed through a ...

Methods : Impact of surgical management in cases o...

In accordance with the WMA Declaration of Helsinki—Ethical Principles for Medical Research Involving Human Subjects, approval was given by the local ethics committee of the Christian-Albrechts-University in Kiel (AZ 132/10). All patients gave informed written consent to participate. A total of 201 sinus floor elevation procedures, which were performed from 2005 to 2006 in the Department of Oral...

Background : Impact of surgical management in case...

Sinus floor elevation procedures have become a predictable and successful treatment, performed when the maxillary alveolar ridge is atrophied and the bone height is not sufficient for primary implantation. If the postoperative course remains uneventful, the outcome is highly predictable [1,2,3]. However, complications may have a negative impact on the overall treatment success. As a common complic...

Abstract : Impact of surgical management in cases ...

Until now, sinus floor elevation represents the gold standard procedure in the atrophic maxilla in order to facilitate dental implant insertion. Although the procedure remains highly predictive, the perforation of the Schneiderian membrane might compromise the stability of the augmented bone and implant success due to chronic sinus infection. The aim of this retrospective cohort study was to show ...

Fig. 7. Multiple graphs comparing A-B distance (he...

Fig. 7. Multiple graphs comparing A-B distance (height bone) (a) and the C-D distance (tissue thickness) (b) among different groups. Differences between groups were assessed by Dunn’s multiple comparison test (*P 

Fig. 6. Graph comparing the data of buccal (B) and...

Fig. 6. Graph comparing the data of buccal (B) and lingual (L) measured the C-D distance (tissue thickness). Group 1 = implant installed in fresh extraction and submerged; group 2 = implants in fresh extraction and immediately exposed; group 3 = implants installed in healed site and submerged; and group 4 = implants in healed site and immediately exposed Fig. 6. Graph comparing the data of bu...

Fig. 5. Graph comparing the data of buccal (B) and...

Fig. 5. Graph comparing the data of buccal (B) and lingual (L) measured the A-B distance (bone height). Group 1 = implant installed in fresh extraction and submerged; group 2 = implants in fresh extraction and immediately exposed; group 3 = implants installed in healed site and submerged; and group 4 = implants in healed site and immediately exposed Fig. 5. Graph comparing the data of buc...

Fig. 4. Images of groups 3 and 4 representing the ...

Fig. 4. Images of groups 3 and 4 representing the implants place in healed alveolar sites. Picrosirius red staining. Original magnification × 4 Fig. 4. Images of groups 3 and 4 representing the implants place in healed alveolar sites. Picrosirius red staining. Original magnification × 4

Fig. 3. Images of groups 1 and 2 representing the ...

Fig. 3. Images of groups 1 and 2 representing the implants place in fresh sockets sites. Picrosirius red staining. Original magnification × 4 Fig. 3. Images of groups 1 and 2 representing the implants place in fresh sockets sites. Picrosirius red staining. Original magnification × 4

Fig. 2. Parameters measured in each group. Crestal...

Fig. 2. Parameters measured in each group. Crestal bone loss is the distance between the implant collar (A) and the first bone contact of the crestal bone (B) = A-B bone height; and, the tissue thickness that is the distance from the implant collar (C) to the more external portion of the tissues (D) = C-D tissue thickness. Picrosirius red staining. Original magnification × 16 Fig. 2. Param...

Fig. 1. Image of the implant (a) and surface (b) u...

Fig. 1. Image of the implant (a) and surface (b) used in the present study Fig. 1. Image of the implant (a) and surface (b) used in the present study

Table 3 Statistical analysis comparing measured di...

  Group    1 2 3 4 Friedman test ...

Table 2 Mean, median, standard deviation, and stan...

  Tissue thickness (C-D distance in mm) Buccal Lingual Group 1 Group 2 Group 3 ...

Table 1 Mean, median, standard deviation, and stan...

  Crestal bone loss (A-B distance in mm) Buccal Lingual Group 1 Group 2 Group 3 ...

About this article : Evaluation of dimensional beh...

Gehrke, S.A., Bragança, L.K., Velasco-Ortega, E. et al. Evaluation of dimensional behavior of peri-implant tissues in implants immediately exposed or submerged in fresh extraction and healed sites: a histological study in dogs. Int J Implant Dent 4, 5 (2018). https://doi.org/10.1186/s40729-018-0120-z Download citation Received: 02 October 2017 Accepted: 10 January 2018 Pu...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Evaluation of dimensional be...

Sergio Alexandre Gehrke, Leana Kathleen Bragança, Eugenio Velasco-Ortega, and Jose Luis Calvo-Guirado declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Evaluation of dimensional beh...

Biotecnos Research Center, Calle Cuareim, 1483, CP: 11.100, Montevideo, Uruguay Sergio Alexandre Gehrke University Catholica San Antonio de Murcia (UCAM), Murcia, Spain Sergio Alexandre Gehrke Implant Dentistry, Seville University, Seville, Spain Leana Kathleen Bragança General Dentistry, Seville University, Seville, Spain Eugenio Velasco-Ortega Implant Dentistry Master, Seville Universit...

References : Evaluation of dimensional behavior of...

Trisi P, Lazzara R, Rao W, Rebaudi A. Bone-implant contact and bone quality: evaluation of expected and actual bone contact on machined and osseotite implant surfaces. Int J Periodontics Restorative Dent. 2002;22(6):535–45. Calvo-Guirado JL, Ortiz-Ruiz AJ, Negri B, López-Marí L, Rodriguez-Barba C, Schlottig F. Histological and histomorphometric evaluation of immediate implant placement on a d...

References : Evaluation of dimensional behavior of...

Spray JR, Black CG, Morris HF, Ochi S. The influence of bone thickness on facial marginal bone response: stage 1 placement through stage 2 uncovering. Ann Periodontol. 2000;5(1):119–28. Bornstein MM, Lussi A, Schmid B, Belser UC, Buser D. Early loading of nonsubmerged titanium implants with a sandblasted and acid-etched (SLA) surface: 3-year results of a prospective study in partially edentulou...

References : Evaluation of dimensional behavior of...

Lang NP, Pun L, Lau KY, Li KY, Wong MC. A systematic review on survival and success rates of implants placed immediately into fresh extraction sockets after at least 1 year. Clin Oral Implants Res. 2012;23(Suppl 5):39–66. Bornstein MM, Valderrama P, Jones AA, Wilson TG, Seibl R, Cochran DL. Bone apposition around two different sandblasted and acid-etched titanium implant surfaces: a histomorpho...

References : Evaluation of dimensional behavior of...

Chen ST, Buser D. Esthetic outcomes following immediate and early implant placement in the anterior maxilla—a systematic review. Int J Oral Maxillofac Implants. 2014;29(Suppl):186–215. Berberi AN, Tehini GE, Noujeim ZF, Khairallah AA, Abousehlib MN, Salameh ZA. Influence of surgical and prosthetic techniques on marginal bone loss around titanium implants. Part I: immediate loading in fresh ex...

References : Evaluation of dimensional behavior of...

Botticelli D, Berglundh T, Lindhe J. Hard-tissue alterations following immediate implant placement in extraction sites. J Clin Periodontol. 2004;31(10):820–8. Araújo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol. 2005;32(2):212–8. Araújo MG, Sukekava F, Wensström JL, Lindhe J. Ridge alterations following implan...

Conclusions : Evaluation of dimensional behavior o...

Within the limitations of this study, our findings suggest that the crestal bone height is larger when implants are inserted in healed areas in comparison with implants installed in fresh extraction sites. Moreover, significant differences were found between non-exposed and immediately exposed implants with regards to crestal bone height position, and higher thickness tissue values in the groups o...

Discussion : Evaluation of dimensional behavior of...

New studies are needed to define the influence of other surface compositions and neck configurations for implants placed in fresh extraction sockets with/or without submerged and the influence of abutment change on crestal bone stabilization during the remodeling process. These would appear to be important factors for improving peri-implant bone and soft tissue stability and clinical outcomes, inc...

Discussion : Evaluation of dimensional behavior of...

In the present study, the implants were positioned in the crestal bone level, by following Bornstein et al. [34, 35] which reported that the implants are often inserted within the bone crest. Tomasi et al. [36] in a clinical trial observed that the implant position conditioned the amount of buccal crest resorption. Moreover, the thickness of the buccal bone plate and the tridimensional positioning...

Discussion : Evaluation of dimensional behavior of...

The immediate implants in fresh sockets have demonstrated a great success rate [18, 22,23,24]. However, the removal of a single tooth followed by immediate placement of an implant results in marked alterations of the ridge in the horizontal as well as in the vertical dimension. The early phases of tissue integration in immediate post-extraction implants have been well documented [1, 25, 26]. The i...

Results : Evaluation of dimensional behavior of pe...

The surgical sites healed uneventfully. All animals presented appropriate healing during the first week following the surgical procedure. Post-surgical inspections for 2 weeks post-operatively indicated the absence of infection or inflammation. All implants presented osseointegration after the proposed period and were available for histological analysis. Direct contact was observed between livin...

Methods : Evaluation of dimensional behavior of pe...

A power analysis was conducted to determine appropriate sample size; although it was determined that 6 samples from each group would generate a 95% confidence limit (G3Power), 10 samples were proposed for each situation to increase the level of significance.

Methods : Evaluation of dimensional behavior of pe...

The hemimandibles were removed with care to preserve the integrity of both peri-implant hard and soft tissues, washed in saline solution and fixed in 10% buffered formalin, and sent for processing at the Laboratory of Ucam-Biotecnos (Murcia, Spain). Specimens were dehydrated in ascending series of alcohol rinses and embedded in a glycol methacrylate resin (Technovit 7200 VLC; Kulzer, Wehrheim, Ger...

Methods : Evaluation of dimensional behavior of pe...

A total of 40 implants were installed (ICI implant, Galimplant, Sarria, Spain), with 3.5 mm in diameter by 10 mm in length. Eight implants in each dog, half per hemimandible. The surface treatment of this implant model is developed by blasting with three different granulometries of Al2O3 and pickling using a hydrofluoric solution (HF) at low temperature and short time, which aims to remove any t...

Background : Evaluation of dimensional behavior of...

Then, the good results were obtained with both techniques (implants placed into fresh alveolus and implants non-submerged); these have been joined together with the objective to reduce the time of the treatment. However, the esthetic results can directly influence by the peri-implant tissue dimension (vertical or horizontal) and position in relationship of the cervical implant portion. In this way...

Background : Evaluation of dimensional behavior of...

After the tooth loss, there is a progressive involution of the alveolar bone both in the horizontal and the vertical dimensions [1, 2]. Moreover, the most rapid reduction in the alveolar bone after tooth extraction occurs during the first 3 months [3, 4]. Implants immediately positioned in alveolus after the surgical extraction of the tooth exhibit a success ranging from 92.7 to 98.0% [5]. Some a...

Abstract : Evaluation of dimensional behavior of p...

The aim of this study was to compare histologically the dimensional behavior of peri-implant tissues during osseointegration of immediately exposed or submerged implant placement in fresh extraction and healed sites. Four fresh extraction and four delayed implant sites were placed in each hemimandible of five dogs at the bone crest level. In 2 implants of each side were installed a healing abutme...

Fig. 8. Distribution of occlusal force in models. ...

Fig. 8. Distribution of occlusal force in models. a Im67, b Im6, c Im4567, d Im456, e MT67, and f MT7. R right TMJ, L left TMJ, 4 first premolar, 5 second premolar, 6 first molar, and 7 second molar. Numbers within circles indicate implant superstructure Fig. 8. Distribution of occlusal force in models. a Im67, b Im6, c Im4567, d Im456, e MT67, and f MT7. R right TMJ, L left TMJ, 4 first prem...

Fig. 7. Initializing models altering the load disp...

Fig. 7. Initializing models altering the load displacement curves of springs Fig. 7. Initializing models altering the load displacement curves of springs

Fig. 6. Springs for opposing teeth and TMJs and lo...

Fig. 6. Springs for opposing teeth and TMJs and load directions. Arrows indicate loads, arrowheads indicate restricted nods, and spiral lines indicate springs Fig. 6. Springs for opposing teeth and TMJs and load directions. Arrows indicate loads, arrowheads indicate restricted nods, and spiral lines indicate springs

Fig. 5. Distribution of occlusal force in the natu...

Fig. 5. Distribution of occlusal force in the natural teeth model displayed in Fig.4 Fig. 5. Distribution of occlusal force in the natural teeth model displayed in Fig.4

Fig. 4. Three-dimensional finite element model wit...

Fig. 4. Three-dimensional finite element model with natural teeth and no defect Fig. 4. Three-dimensional finite element model with natural teeth and no defect

Fig. 3. Load displacement curves of natural teeth ...

Fig. 3. Load displacement curves of natural teeth in FE model Fig. 3. Load displacement curves of natural teeth in FE model

Fig. 2. Load displacement curves of springs : Sign...

Fig. 2. Load displacement curves of springs Fig. 2. Load displacement curves of springs

Fig. 1. Three-dimensional finite element model. Th...

Fig. 1. Three-dimensional finite element model. The tooth roots and implant bodies are displayed with permeability. a Im67, b Im6, c Im4567, d Im456, e MT67, and f MT7 Fig. 1. Three-dimensional finite element model. The tooth roots and implant bodies are displayed with permeability. a Im67, b Im6, c Im4567, d Im456, e MT67, and f MT7

Table 1 Material properties : Significance of mand...

Material Modulus of elasticity (MPa) Poisson ratio References Cortical bone 140,000 ...

About this article : Significance of mandibular mo...

Yoshitani, M., Takayama, Y. & Yokoyama, A. Significance of mandibular molar replacement with a dental implant: a theoretical study with nonlinear finite element analysis. Int J Implant Dent 4, 4 (2018). https://doi.org/10.1186/s40729-018-0117-7 Download citation Received: 13 March 2017 Accepted: 08 January 2018 Published: 27 February 2018 DOI: https://doi.org/10.1186/s407...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Significance of mandibular m...

Author Masazumi Yoshitani, Yoshiyuki Takayama, and Atsuro Yokoyama state that there are no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Significance of mandibular mo...

Division of Oral Functional Science, Department of Oral Functional Prosthodontics, Graduate School of Dental Medicine, Hokkaido University, Kita-13, Nishi-7, Kita-ku, Sapporo, 060-8648, Japan Masazumi Yoshitani & Atsuro Yokoyama Removable Prosthodontics, Hokkaido University Hospital, Hokkaido University, Kita-14, Nishi-5, Kita-Ku, Sapporo, 060-8648, Japan Yoshiyuki Takayama You can also sear...

References : Significance of mandibular molar repl...

Minagi S, Ohmori T, Sato T, Matsunaga T, Akamatsu Y. Effect of eccentric clenching on mandibular deviation in the vicinity of mandibular rest position. J Oral Rehabil. 2000;27:175–9. Yamazaki M, Yugami K, Baba K, Ohyama T. Effect of clenching level on mandibular displacement in Kennedy Class II partially edentulous patients. Int J Prosthodont. 2003;16:183–8. Gibbs CH, Mahan PE, Lundeen HC, B...

References : Significance of mandibular molar repl...

Kim Y, Oh TJ, Misch CE, Wang HL. Occlusal considerations in implant therapy: clinical guidelines with biomechanical rationale. Clin Oral Implants Res. 2005;16:26–35. Korioth TW, Hannam AG. Deformation of the human mandible during simulated tooth clenching. J Dent Res. 1994;73:56–66. van Zyl PP, Grundling NL, Jooste CH, Terblanche E. Three-dimensional finite element model of a human mandible ...

References : Significance of mandibular molar repl...

Baba K, Igarashi Y, Nishiyama A, John MT, Akagawa Y, Ikebe K, Ishigami T, Kobayashi H, Yamashita S. Patterns of missing occlusal units and oral health-related quality of life in SDA patients. J Oral Rehabil. 2008;35:621–8. Kasai K, Takayama Y, Yokoyama A. Distribution of occlusal forces during occlusal adjustment of dental implant prostheses: a nonlinear finite element analysis considering the ...

References : Significance of mandibular molar repl...

Chappuis V, Buser R, Bragger U, Bornstein MM, Salvi GE, Buser D. Long-term outcomes of dental implants with a titanium plasma-sprayed surface: a 20-year prospective case series study in partially edentulous patients. Clin Implant Dent Relat Res. 2013;15:780–90. Bural C, Bilhan H, Cilingir A, Geckili O. Assessment of demographic and clinical data related to dental implants in a group of Turkish ...

Conclusions : Significance of mandibular molar rep...

Within the limitations of this theoretical study, we demonstrated that restoration with the same number of implants as missing teeth shows almost symmetric occlusal force distribution, and it produced less biomechanically stress for a unilateral defect of the mandible. However, if restoration of a missing second molar with an implant is impossible or difficult, then an SDA with implants may also b...

Discussion : Significance of mandibular molar repl...

It should be noted that our results were obtained under conditions of vertical loading by bilaterally balanced muscle activity with tight intercuspation in the correct mandibular position because the horizontal displacement of the premolars and molars was restrained. The actual distribution of occlusal forces may differ due to individual differences in the material properties of the soft tissue. A...

Discussion : Significance of mandibular molar repl...

Occlusal adjustment is usually performed to obtain symmetrical occlusal force distribution in natural dentition. However, occlusal force distribution among natural teeth and implants depends on occlusal force because of the difference of displaceability between a natural tooth and an implant [14, 15]. Therefore, we evaluated the result of the analysis from viewpoints of symmetry of occlusal force ...

Discussion : Significance of mandibular molar repl...

FEA is useful for mechanical simulations of a living body and has been used in implant dentistry research under careful consideration of the analysis conditions [32, 33]. Although some reports have demonstrated that bone density varies according to bone type and location, the material properties of the mandible were homogenous and isotropic in this study. However, the effect of this difference was...

Results : Significance of mandibular molar replace...

In model Im456 (Fig. 8d), under loads 100 and 200 N, the occlusal force at the premolars on the defect side was larger than that in model Im4567 (shown in Fig. 8c). The occlusal force was also larger than that in model MT7 (shown in Fig. 6f). However, the occlusal force at the second premolar under load 200 N was 34.5 N, which was slightly smaller than the occlusal force at the second molar ...

Results : Significance of mandibular molar replace...

In model Im6 (Fig. 8b), the occlusal force at the second premolar under loads 100, 200, 400, and 800 N were 18.3, 37.0, 38.8, and 70.2 N, respectively. The occlusal force was larger than that in model Im67 (shown in Fig. 8a), while it was approximately equivalent to that in model MT7 (shown in Fig. 8f). Under loads 100 and 200 N, the occlusal force at the second premolar on the defect side w...

Results : Significance of mandibular molar replace...

The distributions of occlusal force are shown in Fig. 8. In model MT67 (Fig. 8e), the occlusal force at the first premolar on the defect side was 10.0–86.5 N, which was 1.2–15.0-fold larger than that on the natural dentition side. The occlusal force at the second premolar on the defect side was 24.6–190.1 N, which was 2.6–8.3-fold larger than on the natural dentition side. The occlusal...

Methods : Significance of mandibular molar replace...

Analysis was performed according to the report by Kayumi et al. [15]. In linear finite element analysis (FEA), all teeth maintain perfect contact with antagonists with no stress on occlusal surfaces before loading. However, there must be some occlusal force on the occlusal surface when a mandible is in the intercuspal position. Since the displaceabilities of osseointegrated implants, natural teeth...

Methods : Significance of mandibular molar replace...

Nonlinear characteristics according to the load displacement curve of teeth [21,22,23,24] and cartilage [30] were given to the springs for the opposing teeth and TMJs, respectively (Fig. 2). The nonlinear elasticity of the springs on the teeth and implants simulated displaceability of opposing natural teeth at compression and separation of the occlusal surface from opposing teeth at tension. The...

Methods : Significance of mandibular molar replace...

The 3D FEMs were constructed based on those reported by Kasai et al. [14], Kayumi et al. [15] and consisted of a mandible, natural teeth with the periodontal ligament (PDL), and titanium implant(s) with superstructures in the left premolar and molar regions. The surface of the mandible was generated using measurements of a commercially available model (QS7, SOMSO) of the dentate mandible with a 3...

Background : Significance of mandibular molar repl...

From the viewpoint of occlusal force distribution, when a second molar defect remains without prosthesis, the force might concentrate in the implant, residual teeth, or temporomandibular joints (TMJs). Therefore, the aim of this study was to investigate occlusal force distribution in SDA in the mandible with/without an implant using a three-dimensional (3D) finite element model (FEM).

Background : Significance of mandibular molar repl...

Dental implant treatment has been frequently applied in dental practice as the most important prosthodontic procedure with long-term predictability to restore oral function, maintain occlusion, and improve the quality of life (QoL) of a patient [1]. Clinically, dental implants are mainly applied to correct mandibular distally extended edentulism [2]. However, implant placement in the molar region ...

Abstract : Significance of mandibular molar replac...

Dental implants are frequently applied to unilateral defects in the mandible. However, implant placement in the molar region of the mandible can be difficult due to anatomical structure. The aim of this study was to evaluate the distribution of occlusal force in a mandibular shortened dental arch (SDA) with implants. Three-dimensional finite element (FE) models of the mandible with varying number...

Fig. 3. Proportion of dental implant FEA articles ...

Fig. 3. Proportion of dental implant FEA articles with a validation. (Left) Among totally 522 FEA articles of dental implants which we were able to access English full text up to January 2017, there are only 47 articles with a validation. (Right) The articles with a validation were categorized according to their validation method as follows levels: A, in vivo (human bodies); B, performed in vivo...

Fig. 2. Hierarchy of validations based on their si...

Fig. 2. Hierarchy of validations based on their similarity to real biomechanical behaviors. The articles (n = 47) were categorized according to their validation method as follows: in vivo experiments in humans (n = 1) and other animals (n = 3), model experiments (n = 32), others’ clinical data and past literature (n = 9), and other software (n = 2) Fig. 2. Hierarchy ...

Fig. 1. Flowchart of literature review. An electro...

Fig. 1. Flowchart of literature review. An electronic literature search of PubMed was conducted up to January 2017 using the Medical Subject Headings “dental implants” and “finite element analysis.” After accessing the full texts, the context of each article was searched using the words “valid” and “validation” and articles in which these words appeared were read to determine whe...

Table 1 All studies in the literature that conside...

Ranking Authors Year FE model FEM geometry reference Material properties of tissues a...

About this article : Finite element analysis of de...

Chang, Y., Tambe, A.A., Maeda, Y. et al. Finite element analysis of dental implants with validation: to what extent can we expect the model to predict biological phenomena? A literature review and proposal for classification of a validation process. Int J Implant Dent 4, 7 (2018). https://doi.org/10.1186/s40729-018-0119-5 Download citation Received: 05 November 2017 Accepte...

Rights and permissions : Finite element analysis o...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Finite element analysis of d...

Yuanhan Chang, Abhijit Anil Tambe, Yoshinobu Maeda, Masahiro Wada, and Tomoya Gonda declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Finite element analysis of de...

Department of Prosthodontics, Gerodontology and Oral Rehabilitation, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka, 565-0871, Japan Yuanhan Chang, Yoshinobu Maeda, Masahiro Wada & Tomoya Gonda Mahatma Gandhi Vidyamandir’s Karmaveer Bhausaheb Hiray Dental College & Hospital, Mumbai Agra Road, Panchwati, Nashik, Maharashtra, India Abhijit Anil Tambe You can als...

References : Finite element analysis of dental imp...

Koolstra JH, van Eijden TM. Combined finite-element and rigid-body analysis of human jaw joint dynamics. J Biomech. 2005;38:2431–9. Houdijk H, Bobbert MF, de Haan A. Evaluation of a Hill based muscle model for the energy cost and efficiency of muscular contraction. J Biomech. 2006;39:536–43. Maeda Y, Wood WW. Finite element method simulation of bone resorption beneath a complete denture. J D...

References : Finite element analysis of dental imp...

van Staden RC, Li X, Guan H, Johnson NW, Reher P, Loo YC. A finite element study of short dental implants in the posterior maxilla. Int J Oral Maxillofac Implants. 2014;29:e147–54. Piotrowski B, Baptista AA, Patoor E, Bravetti P, Eberhardt A, Laheurte P. Interaction of bone-dental implant with new ultra low modulus alloy using a numerical approach. Mater Sci Eng C Mater Biol Appl. 2014;38:151...

References : Finite element analysis of dental imp...

Vayron R, Nguyen VH, Bosc R, Naili S, Haïat G. Finite element simulation of ultrasonic wave propagation in a dental implant for biomechanical stability assessment. Biomech Model Mechanobiol. 2015;14:1021–32. Cicciù M, Cervino G, Bramanti E, Lauritano F, Lo Gudice G, Scappaticci L, et al. FEM analysis of mandibular prosthetic overdenture supported by dental implants: evaluation of different re...

References : Finite element analysis of dental imp...

Sotto-Maior BS, Mercuri EG, Senna PM, Assis NM, Francischone CE, Del Bel Cury AA. Evaluation of bone remodeling around single dental implants of different lengths: a mechanobiological numerical simulation and validation using clinical data. Comput Methods Biomech Biomed Engin. 2016;19:699–706. Wang C, Li Q, McClean C, Fan Y. Numerical simulation of dental bone remodeling induced by implant-supp...

References : Finite element analysis of dental imp...

Nagasawa S, Hayano K, Niino T, Yamakura K, Yoshida T, Mizoguchi T, et al. Nonlinear stress analysis of titanium implants by finite element method. Dent Mater J. 2008;27:633–9. Huang HL, Huang JS, Ko CC, Hsu JT, Chang CH, Chen MY. Effects of splinted prosthesis supported a wide implant or two implants: a three-dimensional finite element analysis. Clin Oral Implants Res. 2005;16:466–72. Iplik...

References : Finite element analysis of dental imp...

Chou IC, Lee SY, Jiang CP. Effects of implant neck design on primary stability and overload in a type IV mandibular bone. Int J Numer Method Biomed Eng. 2014;30:1223–37. Chang SH, Huang SR, Huang SF, Lin CL. Mechanical response comparison in an implant overdenture retained by ball attachments on conventional regular and mini dental implants: a finite element analysis. Comput Methods Biomech Bio...

References : Finite element analysis of dental imp...

Alrbata RH, Yu W, Kyung HM. Biomechanical effectiveness of cortical bone thickness on orthodontic microimplant stability: an evaluation based on the load share between cortical and cancellous bone. Am J Orthod Dentofac Orthop. 2014;146:175–82. Nagasao T, Miyamoto J, Kawana H. Biomechanical evaluation of implant placement in the reconstructed mandible. Int J Oral Maxillofac Implants. 2009;24:999...

References : Finite element analysis of dental imp...

Van Staden RC, Guan H, Loo YC. Application of the finite element method in dental implant research. Comput Methods Biomech Biomed Engin. 2006;9:257–70. Maminskas J, Puisys A, Kuoppala R, Raustia A, Juodzbalys G. The prosthetic influence and biomechanics on peri-implant strain: a systematic literature review of finite element studies. J Oral Maxillofac Res. 2016;7:e4. Gass SI. Decision-adding m...

Conclusions : Finite element analysis of dental im...

High-level validation of FEA using in vivo experiments is still rare in the dental implant field. It is necessary to clearly indicate the validation process of the model when a study using FEA is presented. The hierarchy proposed in this study based on the evidence level of the validations can be applied to evaluate the clinical significance of studies using FEA.

Review : Finite element analysis of dental implant...

To explain or analyze the mechanical properties involved in biological phenomena such as motor tasks (mastication, walking, or heart contraction), a time-dependent finite element model may provide a more realistic view. However, if time-dependent performance criteria are considered (the most common is to clarify the influence of musculoskeletal structure on function or the performance of a motor t...

Review : Finite element analysis of dental implant...

Because of the limitations of computer technology, most FEA models [75,76,77,78,79] simplify the skeletal muscle architecture in terms of a uniform fiber length, pennation angle, and line of action and represent the architecture using a Hill-based muscle model. However, how well the modeling of skeletal muscles as one-dimensional strings represents the behavior of the full three-dimensional muscle...

Review : Finite element analysis of dental implant...

Table 1 shows all studies in the literature that considered the need for validation of FEAs. According to these studies, we established a hierarchy based on the evidence level of the validations (A to G, i.e., high to low) (Fig. 2). Level A: validation using living humans Level B: validation using living heterogeneous animals Levels C and D: validation using homogenous and heterogeneous bone ...

Review : Finite element analysis of dental implant...

Level E: model experiment performed using artificial materials (n = 23) [14, 25, 26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46] Artificial materials such as acrylic resin, polyurethane, or plastic bone models were commonly used as embedded “bone” implants in validation experiments. Level E includes the use of special materials and specific methods to measure the force di...

Review : Finite element analysis of dental implant...

We classified all validation processes based on their similarity to real biomechanical behaviors into the following hierarchy (levels A to G) (Fig. 2): Level A: performed in vivo (human bodies) (n = 1) [10] The top level of the hierarchy, level A, includes in vivo methods of FEA validation conducted in humans. In 2006, Heckmann et al. [10] quantified the degree of stress that occurs in the...

Review : Finite element analysis of dental implant...

In total, 601 articles were obtained from the PubMed electronic search using the Medical Subject Headings “dental implants” and “finite element analysis.” After excluding articles for which the full text could not be accessed (n = 69) and that were not written in English (n = 10), 522 articles remained. These articles were searched using the terms “validation,” “validity,” ...

Review : Finite element analysis of dental implant...

FEA studies with validation have recently become more common in the biomechanical field. FEA validations can be divided into two types: (1) direct validation, which involves experiments on the quantities of interest (from basic material characterizations to hierarchical system analysis such as model experiments and in vitro experiments), and (2) indirect validation, which involves the use of liter...

Review : Finite element analysis of dental implant...

Finite element analysis (FEA) has been applied to investigate dental implant designs, the structure and material of the superstructure, and the stability of the surrounding bone [1, 2]. According to PubMed, only 10 FEA studies of dental implants were published in 1990, while 102 papers were published in 2014. FEA has become an increasingly useful tool in the past few decades. In the medical field...

Abstract : Finite element analysis of dental impla...

A literature review of finite element analysis (FEA) studies of dental implants with their model validation process was performed to establish the criteria for evaluating validation methods with respect to their similarity to biological behavior. An electronic literature search of PubMed was conducted up to January 2017 using the Medical Subject Headings “dental implants” and “finite element...

About this article : The influence of implant–ab...

Tsuruta, K., Ayukawa, Y., Matsuzaki, T. et al. The influence of implant–abutment connection on the screw loosening and microleakage. Int J Implant Dent 4, 11 (2018). https://doi.org/10.1186/s40729-018-0121-y Download citation Received: 20 November 2017 Accepted: 24 January 2018 Published: 09 April 2018 DOI: https://doi.org/10.1186/s40729-018-0121-y

Rights and permissions : The influence of implant...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : The influence of implant–a...

The present study was not required ethical approval. Katsuhiro Tsuruta, Yasunori Ayukawa, Tatsuya Matsuzaki, Masafumi Kihara, and Kiyoshi Koyano declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : The influence of implant–ab...

Section of Implant and Rehabilitative Dentistry, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 8128582, Japan Katsuhiro Tsuruta, Yasunori Ayukawa, Tatsuya Matsuzaki, Masafumi Kihara & Kiyoshi Koyano You can also search for this author in PubMed Google Scholar You can also search for this author ...

Funding : The influence of implant–abutment conn...

The experiment was done by self-funding.

References : The influence of implant–abutment c...

Egol KA, Kubiak EN, Fulkerson E, Kummer FJ, Koval KJ. Biomechanics of locked plates and screws. J Orthop Trauma. 2004;18:488–93. Tsuge T, Hagiwara Y, Matsumura H. Marginal fit and microgaps of implant-abutment interface with internal anti-rotation configuration. Dent Mater J. 2008;27:29–34. Scarano A, Valbonetti L, Degidi M, Pecci R, Piattelli A, de Oliveira PS, et al. Implant-abutment conta...

References : The influence of implant–abutment c...

Sakka S, Baroudi K, Nassani MZ. Factors associated with early and late failure of dental implants. J Investig Clin Dent. 2012;3:258–61. Tallarico M, Canullo L, Caneva M, Ozcan M. Microbial colonization at the implant-abutment interface and its possible influence on periimplantitis: a systematic review and meta-analysis. J Prosthodont Res. 2017;61:233–41. Sasada Y, Cochran DL. Implant-abutmen...

Conclusions : The influence of implant–abutment ...

Within the limitation of the present study, after the offset cyclic tensile and compressive loading, the amount of microleakage from implant–abutment interface was smaller in conical connection than in internal parallel connection.

Discussion : The influence of implant–abutment c...

In the present study, chronological increase of the amount of microleakage was observed in all three groups. This is in consistent with previous studies [5, 13, 15, 16]. Sigmoid curves of microleakage in all groups meant that the amount of leakage was large at the early stage of loading. This was in agreement with previous reports. Harder et al. reported that bacterial toxin leak occurred within 5...

Discussion : The influence of implant–abutment c...

In the present study, cyclic tensile and compressive loading were applied to cantilever superstructure. In the clinical situation, both compressive and tensile force was exerted to implant-supported prosthesis, but no previous study has discussed the microleakage using model study under this situation. In case of conical connection, compressive force may have promoted a higher penetration of the a...

Results : The influence of implant–abutment conn...

During the experiment, one (EP) and two (IP) abutment screws out of seven samples were fractured. In this case, abutment screw was changed to new one and experimental procedure was re-run. After the 2000 cycles of compressive tensile loadings, RTV of abutment screw was measured. There were no statistical differences in the RTV among three groups. Standard deviation was largest in the RTV of EP a...

Methods : The influence of implant–abutment conn...

Three kinds of Nobel Biocare implants were employed in the present study, namely, Nobel SpeedyGroovy WP 5.0 × 15 mm (EP), Nobel Replace WP 5.0 × 15 mm (IP), and Nobel Parallel CC RP 5.0 × 15 mm (CC) (n = 7 each) (Nobel Biocare, Kloten, Switzerland). Implant–abutment connections are external, internal parallel, and internal and conical connection, respectively. Implant was e...

Background : The influence of implant–abutment c...

Although promising outcome of implant therapy has been reported, periimplantitis which is known to be one of the most important factors associated with late failure [1] is a serious complication and expected to overcome to obtain successful outcome. It is known that there are some spaces between abutment and implant body which can be a reservoir of microorganisms and other toxic substance [2], and...

Abstract : The influence of implant–abutment con...

There are some spaces between abutment and implant body which can be a reservoir of toxic substance, and they can penetrate into subgingival space from microgap at the implant–abutment interface. This penetration may cause periimplantitis which is known to be one of the most important factors associated with late failure. In the present study, three kinds of abutment connection system, external ...

Fig. 6. Roughness (Sa) box plot : In vitro surface...

Fig. 6. Roughness (Sa) box plot Fig. 6. Roughness (Sa) box plot

Fig. 5. 3D profile : In vitro surface characterist...

Fig. 5. 3D profile Fig. 5. 3D profile

Fig. 4. CLSM : In vitro surface characteristics an...

Fig. 4. CLSM Fig. 4. CLSM

Fig. 3. SEM for localization of EDX analysis : In ...

Fig. 3. SEM for localization of EDX analysis Fig. 3. SEM for localization of EDX analysis

Fig. 2. SEM. White arrow (→) exemplary mark the ...

Fig. 2. SEM. White arrow (→) exemplary mark the droplet like shape of surface as described in the text Fig. 2. SEM. White arrow (→) exemplary mark the droplet like shape of surface as described in the text

Fig. 1. Diagram of different implant areas used fo...

Fig. 1. Diagram of different implant areas used for sampling. 1) Machined (untreated) area. 2) rough (treated) area Fig. 1. Diagram of different implant areas used for sampling. 1) Machined (untreated) area. 2) rough (treated) area

Table 3 Roughness analysis : In vitro surface char...

   Amplitude parameters Group Name Sa (μm) Machined area WhiteSKY ...

Table 2 EDX : In vitro surface characteristics and...

Element composition/semi-quantitative evaluation Location Type Zr at %min–at %max Hf at % Y at %min–at %max...

Table 1 Five commercially available ceramic implan...

NoneTable 1 Five commercially available ceramic implants and surface characteristics

About this article : In vitro surface characterist...

Beger, B., Goetz, H., Morlock, M. et al. In vitro surface characteristics and impurity analysis of five different commercially available dental zirconia implants. Int J Implant Dent 4, 13 (2018). https://doi.org/10.1186/s40729-018-0124-8 Download citation Received: 11 December 2017 Accepted: 08 February 2018 Published: 26 April 2018 DOI: https://doi.org/10.1186/s40729-018...

Rights and permissions : In vitro surface characte...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : In vitro surface characteris...

Not applicable. Not applicable. Beger B, Goetz H, Morlock M, Schiegnitz E, and Al-Nawas B declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : In vitro surface characterist...

Department of Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Augustusplatz 2, 55131, Mainz, Germany B. Beger, M. Morlock, E. Schiegnitz & B. Al-Nawas Biomaterials in Medicine (BioAPP), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany H. Goetz You can also search for this author in Pub...

References : In vitro surface characteristics and ...

Papanagiotou HP, Morgano SM, Giordano RA, Pober R. In vitro evaluation of low-temperature aging effects and finishing procedures on the flexural strength and structural stability of Y-TZP dental ceramics. J Prosthet Dent. 2006;96(3):154–64. Ewais OH, Al Abbassy F, Ghoneim MM, Aboushelib MN. Novel zirconia surface treatments for enhanced osseointegration: laboratory characterization. Int J Dent....

References : In vitro surface characteristics and ...

Ong JL, Carnes DL, Cardenas HL, Cavin R. Surface roughness of titanium on bone morphogenetic protein-2 treated osteoblast cells in vitro. Implant Dent. 1997;6(1):19–24. Schwartz Z, Kieswetter K, Dean DD, Boyan BD. Underlying mechanisms at the bone-surface interface during regeneration. J Periodontal Res. 1997;32(1 Pt 2):166–71. Al-Nawas B, Gotz H. Three-dimensional topographic and metrologic...

References : In vitro surface characteristics and ...

Jacobi-Gresser E, Huesker K, Schutt S. Genetic and immunological markers predict titanium implant failure: a retrospective study. Int J Oral Maxillofac Surg. 2013;42(4):537–43. Wenz HJ, Bartsch J, Wolfart S, Kern M. Osseointegration and clinical success of zirconia dental implants: a systematic review. Int J Prosthodont. 2008;21(1):27–36. Shulte W. The intra-osseous Al2O3 (Frialit) Tuebingen...

Abbreviations : In vitro surface characteristics a...

Aluminum oxide Ceramic injection molding Confocal laser scanning microscopy Energy-dispersive X-ray spectroscopy Hot isostatic pressing Implant Kilovolt Millibar Megapascal Nanometer Area roughness parameter Scanning electron microscopy Sandblasted, Large-grit, Acid-etched Yttrium-stabilized tetragonal zirconium polycrystalline Micrometer

Conclusions : In vitro surface characteristics and...

New ceramic implants are showing a variety of surface characteristics due to different manufacturing processes as shown by other groups [2, 28]. The surface structures of the investigated implants are close to titanium implants. If the surface characteristics really have a high influence on osseointegration, ceramic implants cannot yet compare to the long experience with titanium. However, there a...

Discussion : In vitro surface characteristics and ...

The semi-quantitative energy-dispersive X-ray spectroscopy (EDX) can be used to further analyze the components of the implant surface. None of the implants showed any impurity or unexpected results. Implants 4 and 5 showed yttrium under the detection limit in the EDX analysis. This could be caused by the lower dosage of yttrium endowment in the stabilization processing in comparison to other impla...

Discussion : In vitro surface characteristics and ...

The surface shape (droplet-like surface), which was observed in the SEM samples, can be caused due to the sintering process in which ceramic powder was melted and then formed. Different particle, immersion, and droplet sizes can also change due to possible reasons like usage of various types and dosages of acid for the etching process and change of exposure time to acid effect. A longer exposure t...

Discussion : In vitro surface characteristics and ...

Implant surface characteristics are of ongoing scientific interest. Implants made from titanium are still the most common to be used. Titanium implants are made from alpha-beta alloy which consists of 6% aluminum and 4% vanadium (Ti-6Al-4V). These materials have low density, high strength, and resistance to fatigue and corrosion, and their modulus of elasticity is closer to the bone than any other...

Results : In vitro surface characteristics and imp...

Implant 2 (Sa 1.27 μm ± 0.24) and implant 5 (Sa 1.22 μm ± 0.36) show the highest roughness values (Sa) of all tested implants: Straumann’s pure ceramic implant was blasted and etched and shows the overall highest Sa value in the rough area. Implant 3 (vitaclinical) shows correspondingly lower Sa around 1.05 μm (± 0.17) (Table 3). The lowest Sa value could be found in implant ...

Results : In vitro surface characteristics and imp...

SEM micrographs presented in Fig. 2 demonstrate the dissimilarity of the sample surface microstructure. Implant 1 shows an overall smoother surface and a slaty-like surface without evidence of a typical etching process. The surface shows sparse roughness. Implants 2–4 show deep markings from their brand’s specific etching and sandblasting processes. In × 10,000 magnification, immersions ca...

Methods : In vitro surface characteristics and imp...

Subsequently, the depth map images are imported in the SPIP™ 4.2.6 (Image Metrology) software for roughness and texture evaluation. According to the ISO 25178-2 reference, all surface roughness parameters implemented in SPIP™ are evaluated and classified as amplitude, hybrid, functional, and spatial parameters. Selected values are shown in Table 3.

Methods : In vitro surface characteristics and imp...

Analysis of the element composition of the implant surfaces by means of energy-dispersive X-ray spectroscopy (EDX) was performed with an INCA Energy 350 system (Oxford Instruments, Wiesbaden, Germany) coupled with the SEM Quanta 200 FEG (Fig. 2). Similar to the micro-morphological presentation, each implant was divided into comparable sites of interest. Typical areas were selected and evaluated (...

Methods : In vitro surface characteristics and imp...

The following five commercially available dental zirconia implants were used in this study (Table 1). Bredent whiteSKY™ implant (I1) is made from unground Brezirkon™, an yttrium oxide (Y2O3)-stabilized tetragonal polycrystalline zirconium oxide and is sandblasted. Zirconium oxide is endowed with 3 mol% yttrium oxide to gain a rectangle and room temperature stable structure [17]. Straumann® ...

Background : In vitro surface characteristics and ...

Dental implants have become a well-established treatment method for oral rehabilitation after tooth loss. Pure titanium is still the material of choice when it comes to dental intraosseous implants and has been used for decades. However, titanium implants have esthetic limitations, especially in the front aspect of the maxillary jaw. The recession of the gingiva can lead to visible implant necks. ...

Abstract : In vitro surface characteristics and im...

The aim of this study was to assess surface characteristics, element composition, and surface roughness of five different commercially available dental zirconia implants. Five zirconia implants (Bredent whiteSKY™ (I1), Straumann® PURE Ceramic (I2), ceramic.implant vitaclinical (I3), Zeramex® (I4), Ceralog Monobloc M10 (I5)) were evaluated. The evaluation was performed by means of scanning el...

Fig. 7. Box and Whisker plot representing median a...

Fig. 7. Box and Whisker plot representing median and range values of membrane thicknesses with different morphologies Fig. 7. Box and Whisker plot representing median and range values of membrane thicknesses with different morphologies

Fig. 6. Box plot representing mean values of membr...

Fig. 6. Box plot representing mean values of membrane thicknesses for the investigated groups Fig. 6. Box plot representing mean values of membrane thicknesses for the investigated groups

Fig. 5. Endoscopic view from the crestal osteotomy...

Fig. 5. Endoscopic view from the crestal osteotomy site showing perforation of the sinus lining under the power of magnification and illumination of the endoscope Fig. 5. Endoscopic view from the crestal osteotomy site showing perforation of the sinus lining under the power of magnification and illumination of the endoscope

Fig. 4. Schematic drawing showing entrance of the ...

Fig. 4. Schematic drawing showing entrance of the endoscope from the crestal osteotomy site after sinus membrane elevation to assess the integrity of the membrane Fig. 4. Schematic drawing showing entrance of the endoscope from the crestal osteotomy site after sinus membrane elevation to assess the integrity of the membrane

Fig. 3. Endoscopic view from the lateral sinus wal...

Fig. 3. Endoscopic view from the lateral sinus wall showing the dome-shape elevation of sinus lining Fig. 3. Endoscopic view from the lateral sinus wall showing the dome-shape elevation of sinus lining

Fig. 2. Malleting instruments supplied from InnoBi...

Fig. 2. Malleting instruments supplied from InnoBioSurg (IBS) Company, Korea. a magic sinus splitter: used to widen and split the crest. b magic sinus lifter: used to lift the available bone with its attached membrane Fig. 2. Malleting instruments supplied from InnoBioSurg (IBS) Company, Korea. a magic sinus splitter: used to widen and split the crest. b magic sinus lifter: used to lift the a...

Fig. 1. A trephined hole (4 mm bone) in the later...

Fig. 1. A trephined hole (4 mm bone) in the lateral wall of the maxillary sinus to allow entrance of the endoscope Fig. 1. A trephined hole (4 mm bone) in the lateral wall of the maxillary sinus to allow entrance of the endoscope

Table 4 Chi square test showing perforation rate b...

Morphology No perforation Perforation P value No. (%) No. (%) Flat (n = 4) ...

Table 3 Descriptive statistics, results of Kruskal...

Morphology Mean ± SD (mm) Median (range) P value Perforation rate (%) Flat (n = 4) ...

Table 2 Chi square test showing perforation rate a...

Group No perforation Perforation P value No. (%) No. (%) Group (A) ...

Table 1 Descriptive statistics of membrane thickne...

Group Membrane thickness Mean ± SD (mm) Median (range) Percentage (%) (from total) Perforation rate (%...

About this article : Crestal endoscopic approach f...

Elian, S., Barakat, K. Crestal endoscopic approach for evaluating sinus membrane elevation technique. Int J Implant Dent 4, 15 (2018). https://doi.org/10.1186/s40729-018-0126-6 Download citation Received: 08 November 2017 Accepted: 20 March 2018 Published: 17 May 2018 DOI: https://doi.org/10.1186/s40729-018-0126-6

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Ethics declarations : Crestal endoscopic approach ...

Faculty of Dentistry, Minia University ethics committee approved the study. All patients gave the consent to participate in the surgery. All patients approved for publications. The authors Samy Elian and Khaled Barakat declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Crestal endoscopic approach f...

Faculty of Dentistry, Royal College of Surgeons in Ireland (RCSI), Dublin, Ireland Samy Elian Faculty of Dental Surgery, Royal College of Physicians and Surgeons of Glasgow, Glasgow, Scotland Samy Elian Dentistry Department, Sohag University Hospital, Sohag, Egypt Samy Elian Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Minya University, Minya, Egypt Khaled Barakat You c...

Acknowledgements : Crestal endoscopic approach for...

We would like to express our gratitude to Ass. Prof. Hamed Gad for his clinical collaboration. This research was carried out without funding. The data supporting our findings can be requested for free at any time.

References : Crestal endoscopic approach for evalu...

Berengo M, Sivolella S, Majzoub Z, Cordioli G. Endoscopic evaluation of the bone-added osteotome sinus floor elevation procedure. Int J Oral Maxillofac Surg. 2004;33(2):189–94. Nkenke E, Schlegel A, Schultze-Mosgau S, Neukam FW, Wiltfang J. The endoscopically controlled osteotome sinus floor elevation: a preliminary prospective study. Int J Oral Maxillofac Implants. 2002;17(4):557–66. Nahlie...

References : Crestal endoscopic approach for evalu...

Summers RB. A new concept in maxillary implant surgery: the osteotome technique. Compendium. 1994;15(2):152. 54-6, 58 passim; quiz 62 Zitzmann NU, Scharer P. Sinus elevation procedures in the resorbed posterior maxilla. Comparison of the crestal and lateral approaches. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998;85(1):8–17. Ardekian L, Oved-Peleg E, Mactei EE, Peled M. The clinical ...

Discussion : Crestal endoscopic approach for evalu...

Crestal sinus lifting technique is a simple less invasive procedure. Nevertheless, it suffers a serious disadvantage of being a blind technique. Thus, perforation can easily occur without being detected which will lead to later implant failure especially when bone graft is added [1, 12,13,14]. We used endoscopic-assisted evaluation as a dependable method to assess the safety of the Schneiderian me...

Results : Crestal endoscopic approach for evaluati...

On the other hand, assessing the effect of membrane morphology pattern on the perforation risk revealed that the polyp type has the lowest risk of perforation, whereas the irregular type represents the most insecure pattern. There was a relation between different membrane morphology and perforation.

Results : Crestal endoscopic approach for evaluati...

All patients tolerated the procedure without major complications. Minor complications included postoperative swelling, edema, and pain that were managed by antibiotic and anti-inflammatory drugs. All implants were successfully osseo-integrated and loaded after about 6 months. The floor was lifted without perforation in 83.33% of cases. The lifter was able to raise and stretch the sinus membrane ...

Patients and methods : Crestal endoscopic approach...

After completing the elevation of the Schneiderian membrane, the endoscope (70° lens) was removed from the lateral wall of the maxillary sinus and re-inserted (with 0°) from the crestal osteotomy site of the implant (Fig. 4) to check the integrity of the Schneiderian membrane, as well as to ensure the absence of any undetected minor perforation (Fig. 5). The implant was finally inserted in the...

Patients and methods : Crestal endoscopic approach...

Twelve patients (4 males and 8 females) ranging in age from 25 to 60 years were included in the study. All patients have bone height ranging 3–5 mm below the sinus membrane. They all performed closed sinus lifting and simultaneous immediate implant insertion. Under local anesthesia, the flap was elevated and retracted exposing the crestal and buccal bone. A trephine bur 4 mm diameter on hand...

Introduction : Crestal endoscopic approach for eva...

The evolution of closed sinus lift techniques since 1994 [1] was proposed as a less invasive method for management of atrophic posterior maxillae [2]. However, it is a blind technique that lacks the ability to confirm an intact sinus floor elevation without perforation and thus represented a real shortcoming [3]. Various forms of osteotome lifters were designed to guarantee safe elevation of maxil...

Fig. 5. ROC analyses of PICF calprotectin and NTx ...

Fig. 5. ROC analyses of PICF calprotectin and NTx to predict peri-implant diseases. PICF samples were collected from sites with and without peri-implant diseases (n = 74). Calprotectin (a) and NTx (b) amounts in PICF samples were subjected to ROC curve analysis. AUC values for calprotectin and NTx amounts were 0.964 (95% CI = 0.913–0.996, P 

Fig. 4. Correlation between NTx amounts and PD or ...

Fig. 4. Correlation between NTx amounts and PD or BL rates. a The correlation between PICF NTx amounts and PD was evaluated in PICF samples from peri-implant disease and healthy groups (n = 74, ρ = 0.434, P 

Fig. 3. Relationship between PICF calprotectin amo...

Fig. 3. Relationship between PICF calprotectin amounts and PD or GI scores. a The relationship between PICF calprotectin amounts and PD was evaluated in PICF samples from peri-implant disease and healthy groups (n = 74, ρ = 0.709, P 

Fig. 2. Comparison of NTx levels in PICF. NTx amou...

Fig. 2. Comparison of NTx levels in PICF. NTx amounts (a) in PICF samples from peri-implant disease sites (n = 40, diseased) and non-diseased sites (n = 34, healthy) were measured by ELISA, and its concentration (b) was normalized by the volume of PICF. Horizontal bars show the mean values of each group. ‡P 

Fig. 1. Comparison of calprotectin levels in PICF....

Fig. 1. Comparison of calprotectin levels in PICF. PICF samples were collected from peri-implant disease sites (n = 40, diseased) and non-diseased sites (n = 34, healthy). Calprotectin amounts (a) were measured by ELISA, and its concentration (b) was normalized by the volume of PICF. Horizontal bars show the mean values of each group. *P 

Table 1 Characteristics of participants and examin...

Participants  Number of participants 35    Gender (male/female) 10:25    Age (y...

About this article : Calprotectin and cross-linked...

Sakamoto, E., Kido, R., Tomotake, Y. et al. Calprotectin and cross-linked N-telopeptides of type I collagen levels in crevicular fluid from implant sites with peri-implant diseases: a pilot study. Int J Implant Dent 4, 26 (2018). https://doi.org/10.1186/s40729-018-0138-2 Download citation Received: 22 December 2017 Accepted: 25 May 2018 Published: 13 September 2018 DOI: h...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Calprotectin and cross-linke...

The present study was approved by the Ethics Committees of Tokushima University Hospital (nos. 2368 and 2719) in accordance with the Helsinki Declaration of 2013. Participants with peri-implants gave their written informed consent after receiving an explanation of this clinical study. Authors Eijiro Sakamoto, Rie Kido, Yoritoki Tomotake, Yoshihito Naitou, Yuichi Ishida and Jun-ichi Kido declare t...

Author information : Calprotectin and cross-linked...

Correspondence to Jun-ichi Kido.

Author information : Calprotectin and cross-linked...

Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto, Tokushima, 770-8504, Japan Eijiro Sakamoto, Rie Kido & Jun-ichi Kido Oral Implant Center, Tokushima University Hospital, Tokushima, Japan Yoritoki Tomotake & Yoshihito Naitou Department of Oral and Maxillofacial Prosthodontics, Institute of Biomedical S...

Acknowledgements : Calprotectin and cross-linked N...

We thank Dr. Toyoko Tajima (Oral Implant Center, Tokushima University Hospital) and Dr. Toshihiko Nagata, Dr. Koji Naruishi, Dr. Hiromichi Yumoto, Dr. Masami Ninomiya, Dr. Mika Bando, Dr. Yuji Inagaki, Dr. Chie Mihara, Dr. Takahisa Ikuta, Mr. Ryosuke Takagi, and Mr. Kohei Nonaka (Department of Periodontology and Endodontology, Institute of Biomedical Sciences, Tokushima University Graduate School)...

References : Calprotectin and cross-linked N-telop...

Download references

References : Calprotectin and cross-linked N-telop...

Aboyoussef H, Carter C, Jandinski JJ, Panagakos FS. Detection of prostaglandin E2 and matrix metalloproteinases in implant crevicular fluid. Int J Oral Maxillofac Implants. 1998;13:689–96. Melo RF, Lopes BM, Shibli JA, Marcantonio E Jr, Marcantonio RA, Galli GM. Interleukin-1β and interleukin-6 expression and gene polymorphisms in subjects with peri-implant disease. Clin Implant Dent Relat Res...

References : Calprotectin and cross-linked N-telop...

Becerik S, Afacan B, Öztürk VÖ, Atmaca H, Emingil G. Gingival crevicular fluid calprotectin, osteocalcin and cross-linked N-terminal telopeptide levels in health and different periodontal diseases. Dis Markers. 2011;31:343–52. Becerik S, Gürkan A, Afacan B, Özgen ÖV, Atmac H, Töz H, et al. Gingival crevicular fluid osteocalcin, N-terminal telopeptides, and calprotectin levels in cyclospo...

References : Calprotectin and cross-linked N-telop...

Fagerhol MK, Andersson KB, Naess-Andersen CF, Brandtzaeg P, Dale I. Calprotectin (the L1 leukocyte protein). In: Smith UL, Dedman JR, editors. Stimulus response coupling: the role of intracellular calcium-binding proteins. Boca Raton, FL: CRC Press; 1990. p. 187–210. Stříž I, Trebichavský I. Calprotectin—a pleiotropic molecule in acute and chronic inflammation. Physiol Res. 2004;53:245–...

References : Calprotectin and cross-linked N-telop...

Mombelli A, Müller N, Cionca N. The epidemiology of peri-implantitis. Clin Oral Implants Res. 2012;23(Suppl 6):67–76. Figuero E, Graziani F, Sanz I, Herrera D, Sanz M. Management of peri-implant mucositis and peri-implantitis. Periodontol. 2000;2014(66):255–73. Hämmerle CHF, Glauser R. Clinical evaluation of dental implant treatment. Periodontol. 2000;2004(34):230–9. Heitz-Mayfield LJA....

Abbreviations : Calprotectin and cross-linked N-te...

Aspartate aminotransferase Bone loss Bleeding on probing Cumulative interceptive supportive therapy Gingival crevicular fluid Gingival index Cross-linked C-telopeptide of type I collagen Interleukin-1β Matrix metalloproteinase-8 Nuclear factor-κB Cross-linked N-telopeptide of type I collagen Osteocalcin Probing depth Peri-implant crevicular fluid Receptor activator of NF-κB ligand...

Conclusions : Calprotectin and cross-linked N-telo...

Calprotectin and NTx in PICF are markers of inflammation and bone resorption in peri-implant tissues and may be useful diagnostic markers for peri-implant diseases.

Discussion : Calprotectin and cross-linked N-telop...

Treatments for peri-implant diseases are selected by CIST [6], in which clinical indicators including PD, BOP, implant mobility, and BL on radiographs are used to diagnose peri-implant diseases. However, these clinical indicators are not considered to be sufficiently accurate or objective for the diagnosis of peri-implant diseases. Biomarkers in PICF contribute to the diagnosis of peri-implant dis...

Discussion : Calprotectin and cross-linked N-telop...

We did not classify peri-implant diseases into peri-implant mucositis and peri-implantitis in this pilot study. Peri-implant mucositis does not show BL, whereas peri-implantitis shows BL of more than 2.5 or 3 mm on intra-oral radiographs [39, 40]. Figuero et al. [2] introduced plural diagnostic criteria for peri-implant mucositis and peri-implantitis. Rakic et al. [5] defined peri-implantitis as ...

Discussion : Calprotectin and cross-linked N-telop...

Diagnostic studies on peri-implant diseases using biomarkers in PICF have been performing because clinical indicators do not necessarily lead to an accurate evaluation of peri-implant diseases [5, 7, 8, 32]. Calprotectin levels were significantly higher in periodontitis GCF than in healthy GCF, and thus, calprotectin is regarded as a useful inflammatory marker for periodontal diseases [16, 17, 19]...

Results : Calprotectin and cross-linked N-telopept...

NTx amounts in PICF samples correlated with PD at PICF sampling sites (ρ = 0.434, P 

Results : Calprotectin and cross-linked N-telopept...

Thirty-four of PICF samples were collected from healthy peri-implant sites and forty samples from diseased sites (Table 1). The mean PD in diseased sites was 4.70 mm, which was significantly deeper than that of healthy sites (2.32 mm). The mean GI score of diseased sites was 1.5, which was significantly higher than that of healthy sites. A significant difference was observed in the BOP-positive...

Methods : Calprotectin and cross-linked N-telopept...

Calprotectin in PICF samples was determined using Calprotectin Human ELISA kit® (Hycult Biotech, PB Uden, the Netherlands) according to the instruction manual. Briefly, the extracted PICF solution was diluted to 100–200-fold using dilution buffer provided in the kit. The diluted PICF solution was added to wells coated with an antibody of human calprotectin and incubated at room temperature for ...

Methods : Calprotectin and cross-linked N-telopept...

The present clinical study was approved by the Ethics Committees of Tokushima University Hospital (nos. 2368 and 2719) in accordance with the Helsinki Declaration of 2013 and performed from November 2016 to August 2017. Patients who received dental implants from 3 to 9 years ago, had healthy or diseased implants with peri-implant diseases, and visited at Tokushima University Hospital for the main...

Background : Calprotectin and cross-linked N-telop...

Calprotectin (S100A8/S100A9) is an inflammation-related protein that is produced in leukocytes, macrophages/monocytes, and epithelial cells, and its level increases in several inflammatory diseases including ulcerative colitis, rheumatoid arthritis, and cystic fibrosis [14, 15]. Calprotectin was previously detected in GCF, and its level was significantly higher in GCF from periodontal disease site...

Background : Calprotectin and cross-linked N-telop...

Dental treatments with implants are now being widely performed due to advances in the development of surgical procedures for dental implants and prosthodontics. However, the incidence of peri-implant diseases has been increasing with implant placement [1], and thus, the early detection of these diseases is important for maintaining dental implants. Peri-implant diseases with inflammation and the d...

Abstract : Calprotectin and cross-linked N-telopep...

Peri-implant crevicular fluid (PICF) contains calprotectin and NTx, which are markers for inflammation and bone resorption, respectively. The aims of this pilot study were to compare calprotectin and NTx levels in PICF from implant sites with or without peri-implant diseases and to evaluate the usefulness of calprotectin and NTx as diagnostic markers for peri-implant diseases. Thirty-five patient...

Fig. 5. Mean and standard deviation of the biomech...

Fig. 5. Mean and standard deviation of the biomechanical data at both observation periods (P > 0.05). a Removal torque. b Removal energy. c Connection stiffness Fig. 5. Mean and standard deviation of the biomechanical data at both observation periods (P > 0.05). a Removal torque. b Removal energy. c Connection stiffness

Fig. 4. Comparison among secant and tangent method...

Fig. 4. Comparison among secant and tangent methods to calculate the connection stiffness values, which reveals the absence of mathematical discrepancy Fig. 4. Comparison among secant and tangent methods to calculate the connection stiffness values, which reveals the absence of mathematical discrepancy

Fig. 3. Representative curve of the torque test fo...

Fig. 3. Representative curve of the torque test for implants. a Graph of torque versus angular displacement with linear regression curve, and equation, representing the connection stiffness. b Determination procedure of unscrewing implant work up to test’s maximum torque Fig. 3. Representative curve of the torque test for implants. a Graph of torque versus angular displacement with linear r...

Fig. 2. Adaptation of Shimadzu universal testing m...

Fig. 2. Adaptation of Shimadzu universal testing machine for performing removal torque test of dental implants. a General view. b Assembly detail of connection between Allen keys socket and the implant placed in the tibia Fig. 2. Adaptation of Shimadzu universal testing machine for performing removal torque test of dental implants. a General view. b Assembly detail of connection between Allen...

Fig. 1. Two pairs of implants (10 mm × 4 mm...

Fig. 1. Two pairs of implants (10 mm × 4 mm, L × Ø) from each of the experimental groups were placed in each tibia with an alternating fashion in terms of medio-distal positioning regarding the group, but with the first group chosen at random. Implants were placed with an inter-implant distance of 1 cm Fig. 1. Two pairs of implants (10 mm × 4 mm, L × Ø) from each of...

Table 2 Spearman rank correlation coefficient valu...

    Removal torque Removal energy Connection stiffness Spearman’s rho Removal torque Coefficient ...

Table 1 One-way ANOVA variance and Tukey’s post ...

  Sum of squares df Mean square F Sig. (P value) Removal torque Between groups ...

About this article : Interfacial biomechanical pro...

de Jesus, R.N.R., Carrilho, E., Antunes, P.V. et al. Interfacial biomechanical properties of a dual acid-etched versus a chemically modified hydrophilic dual acid-etched implant surface: an experimental study in Beagles. Int J Implant Dent 4, 28 (2018). https://doi.org/10.1186/s40729-018-0139-1 Download citation Received: 01 February 2018 Accepted: 29 May 2018 Published: 2...

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Interfacial biomechanical pr...

The animal experimental protocol was approved by the Bioethics Committee for Animal Experimentation (CEUA, protocol no. 098/10) at the Federal University of Uberlândia. Rainde Naiara Rezende de Jesus, Eunice Carrilho, Pedro V. Antunes, Amílcar Ramalho, Camilla Christian Gomes Moura, Andreas Stavropoulos, and Darceny Zanetta-Barbosa declare that they have no competing interests. Springer Nature...

Author information : Interfacial biomechanical pro...

You can also search for this author in PubMed Google Scholar RNRJ participated in the study concept and design and performed the animal operations, biomechanical test, and data analysis and interpretation. EC, PVA, and AR contributed to define the test protocol and performed the biomechanical test and data analysis. CCGM and DZ participated in the study concept and desig...

Author information : Interfacial biomechanical pro...

Department of Periodontology, Faculty of Odontology, Malmö University, Carl Gustafs väg 34, 205-06, Malmö, Sweden Rainde Naiara Rezende de Jesus & Andreas Stavropoulos IBILI, Faculty of Medicine, University of Coimbra, Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal Rainde Naiara Rezende de Jesus & Eunice Carrilho CEMUC, Mechanical Engineering Department, University of ...

Acknowledgements : Interfacial biomechanical prope...

The assistance of fifth-year dental students of the Federal University of Uberlândia in surgeries, including auscultation, and other practicalities is highly appreciated. The Brazilian Federal Agency for Support and Evaluation of Graduate Education (CAPES research fellow, Full PhD Program, process no. 0975-14.1) provided funding and Neodent® (Curitiba, PR, Brazil) produced the titanium implants...

References : Interfacial biomechanical properties ...

Kim S, Lee S, Cho I, Kim S, Kim T. Rotational resistance of surface-treated mini-implants. Angle Orthod. 2009;79(5):899–907. https://doi.org/10.2319/090608-466.1. Download references

References : Interfacial biomechanical properties ...

de Jesus RNR, Stavropoulos A, Oliveira MTF, Soares PBF, Moura CCG, Zanetta-Barbosa D. Histomorphometric evaluation of a dual acid-etched vs. a chemically modified hydrophilic dual acid-etched implant surface. An experimental study in dogs. Clin Oral Implants Res. 2017;28(5):551–7. https://doi.org/10.1111/clr.12833. Frost HM. Skeletal structural adaptations to mechanical usage (SATMU): 1. Redefi...

References : Interfacial biomechanical properties ...

Boyan BD, Cheng A, Olivares-Navarrete R, Schwartz Z. Implant surface design regulates mesenchymal stem cell differentiation and maturation. Adv Dent Res. 2016;28(1):10–7. https://doi.org/10.1177/0022034515624444. Mamalis AA, Silvestros SS. Analysis of osteoblastic gene expression in the early human mesenchymal cell response to a chemically modified implant surface: an in vitro study. Clin Oral ...

References : Interfacial biomechanical properties ...

Wall I, Donos N, Carlqvist K, Jones F, Brett P. Modified titanium surfaces promote accelerated osteogenic differentiation of mesenchymal stromal cells in vitro. Bone. 2009;45(1):17–26. https://doi.org/10.1016/j.bone.2009.03.662. Mamalis AA, Markopoulou C, Vrotsos I, Koutsilirieris M. Chemical modification of an implant surface increases osteogenesis and simultaneously reduces osteoclastogenesis...

References : Interfacial biomechanical properties ...

Cochran DL, Jackson JM, Jones AA, Jones JD, Kaiser DA, Taylor TD, et al. A 5-year prospective multicenter clinical trial of non-submerged dental implants with a titanium plasma-sprayed surface in 200 patients. J Periodontol. 2011;82(7):990–9. https://doi.org/10.1902/jop.2011.100464. Wallkamm B, Ciocco M, Ettlin D, Syfrig B, Abbott W, Listrom R, et al. Three-year outcomes of Straumann Bone Level...

Notes : Interfacial biomechanical properties of a ...

Chemically modified sandblasted, large grit, and acid-etched surfaces Sandblasted, large grit, and acid-etched surfaces Neodent, Rua Benjamin Lins, 742, Curitiba, PR 80420–100, Brazil Shimadzu Corporation, Nishinokyo Kuwabara-cho, Nakagyo-ku, Kyoto 604–8511, Japan IBM Corporation v.23, 1 New Orchard Road, Armonk, New York 10, 504–1722, USA

Conclusions : Interfacial biomechanical properties...

No significant differences were observed between the specific hydrophilic (SAE-HD) and hydrophobic (SAE) surfaces evaluated in this study, in terms of biomechanical properties during the early osseointegration period.

Discussion : Interfacial biomechanical properties ...

In fact, the observed lack of differences between the groups could be attributed to the relatively low number of specimens per group. According to the observed data herein, applying a high power (80%) with the present sample size would had revealed a relatively large difference in removal torque equivalent to 43% between the experimental groups. Regarding removal energy and connection stiffness, t...

Discussion : Interfacial biomechanical properties ...

On the other hand, lack of significant differences between the two groups in the present experiment could be due to the fact that the effect of hydrophilicity, in terms of accelerating bone healing and osseointegration, was unfolded before the first evaluation time-point of 2 weeks, i.e., during the very early healing period. Consistently, pre-clinical investigations show the potential of chemica...

Discussion : Interfacial biomechanical properties ...

Improving surface wettability aims to increase the implant surface area achieving most favorable protein adsorption and cellular adhesion and thereby to positively regulate the biological response at the initial osseointegration process. Thus, the superior potential of superhydrophilic surfaces in enhancing osseointegration at early stages of bone formation may also enhance their load-bearing capa...

Results : Interfacial biomechanical properties of ...

No remarkable events were observed during the surgical procedures and the subsequent healing period. The relative biomechanical performance of both experimental implant surfaces is illustrated in a representative graph of removal torque versus angular displacement. The removal torque, removal energy, and connection stiffness values are described in terms of mean, standard deviation, and 95% confid...

Methods : Interfacial biomechanical properties of ...

To assess the biomechanical strength of the bone-implant interface, the following parameters were assessed: (a) maximum removal torque (N cm) (primary outcome measure), obtained during the unscrewing process (primary outcome measure); (b) connection stiffness (N cm/rad), corresponding to the ratio between removal torque and angular displacement (secondary outcome measure); and (c) removal energy...

Methods : Interfacial biomechanical properties of ...

Six male Beagle dogs (~ 1.5 years old), weighting between 13 and 15 kg, were used in the present study. All animals were acclimatized in the experimental animal care facility of Federal University of Uberlândia for 2 weeks previously to the experimental procedures and randomly pair-housed in standard shelters (1 × 1.5 m kennel) to allow environmental enrichment (i.e., variety of toys, ...

Methods : Interfacial biomechanical properties of ...

The present preclinical in vivo study is reported according to the Animal Research: Reporting of In Vivo Experiments (ARRIVE) guidelines, in regard with relevant items [33]. The animal experimental protocol was approved by the Bioethics Committee for Animal Experimentation (CEUA, protocol no. 098/10) at the Federal University of Uberlândia and followed the normative guidelines of the National Cou...

Background : Interfacial biomechanical properties ...

Evaluation of biological effects and biomechanical properties of innovative technologies in the field of implant dentistry in preclinical animal models, prior to translational research, complies with standard regulations [33]. Thus, the aim of this preclinical animal study was to evaluate the effect of surface microtopography and chemistry on the biomechanical properties of implants with a sandbla...

Background : Interfacial biomechanical properties ...

The progressive evolution of oral implant surface technology (i.e., micro to nanotopography and chemical composition) [1, 2], implant macrogeometry, surgical procedures [3,4,5], and loading protocols [6,7,8] has resulted in high survival and clinical success rates [9]. Accordingly, chemically active micro and nanostructured implant surfaces, presenting moderate surface roughness (Ra/Sa values betw...

Abstract : Interfacial biomechanical properties of...

In this study, no significant differences were observed between the specific hydrophilic (SAE-HD) and hydrophobic (SAE) surfaces evaluated, in terms of biomechanical properties during the early osseointegration period.

Abstract : Interfacial biomechanical properties of...

The high survival clinical success rates of osseointegration are requisites for establishing a long-term biomechanical fixation and load-bearing potential of endosseous oral implants. The objective of this preclinical animal study was to evaluate the effect of surface microtopography and chemistry on the early stages of biomechanical rigidity with a sandblasted, dual acid-etched surface, with or w...

Fig. 1. PRISMA flow diagram of literature search :...

Fig. 1. PRISMA flow diagram of literature search Fig. 1. PRISMA flow diagram of literature search

Table 8 In vivo studies using animal models that ...

Study (year) Sample (size) Treatment group (size) Methodology Parameter ...

Table 7 Clinical studies that investigated the eff...

Study (year) Sample (size) Treatment group (size) Methodology Parameter ...

Table 6 In vitro studies that investigated the eff...

Study (year) Sample Treatment group Methodology Parameter Outco...

Table 5 Items of the ARRIVE Guidelines [18] : The ...

Item Domain 5 Ethical statement 6 Study design ...

Table 4 Quality assessment of the methodology of t...

Study 5 6 7 8 9 ...

Table 3 Quality and bias assessment of human clini...

Study Random sequence generation Allocation concealment Blinding of participants/personnel Blinding of outcome assessment ...

Table 2 Modified CONSORT checklist of items for re...

Item Domain 1 Abstract: structured summary of trial design, methods, results, and conclusions Introduction ...

Table 1 Quality assessment of in vitro studies acc...

Study 1 2 3 4 5 ...

About this article : The effect of non-steroidal a...

Luo, J., Miller, C., Jirjis, T. et al. The effect of non-steroidal anti-inflammatory drugs on the osteogenic activity in osseointegration: a systematic review. Int J Implant Dent 4, 30 (2018). https://doi.org/10.1186/s40729-018-0141-7 Download citation Received: 22 May 2018 Accepted: 13 July 2018 Published: 09 October 2018 DOI: https://doi.org/10.1186/s40729-018-0141-7

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : The effect of non-steroidal ...

Not applicable Not applicable Jie Denny Luo, Catherine Miller, Tamara Jirjis, Masoud Nasir, and Dileep Sharma declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : The effect of non-steroidal a...

College of Medicine & Dentistry, James Cook University, 14-88 McGregor Road, Smithfield, QLD, 4878, Australia Jie Denny Luo, Tamara Jirjis, Masoud Nasir & Dileep Sharma College of Public Health, Medical and Veterinary Sciences, James Cook University, 14-88 McGregor Road, Smithfield, QLD, 4878, Australia Catherine Miller You can also search for this author in PubMed...

Acknowledgements : The effect of non-steroidal ant...

The authors acknowledge and are grateful for the help and preparation of manuscript by the supporting research supervisors: Dr. Ernest Jennings and Prof. Alan Nimmo. The systematic review is funded by James Cook University College of Medicine and Dentistry as part of a Dentistry Honours Research Project. A meta-analysis was not conducted for this systematic review. The critical analysis tables t...

References : The effect of non-steroidal anti-infl...

Winnett B, Tenenbaum HC, Ganss B, Jokstad A. Perioperative use of non-steroidal anti-inflammatory drugs might impair dental implant osseointegration. Clin Oral Implants Res. 2016;27(2):E1–7. Goodman SB, Ma T, Mitsunaga L, Miyanishi K, Genovese MC, Smith RL. Temporal effects of a COX-2-selective NSAID on bone ingrowth. J Biomed Mater Res A. 2005;72((3):279–87. Ribeiro FV, Cesar-Neto JB, Nocit...

References : The effect of non-steroidal anti-infl...

Marquez-Lara A, Hutchinson ID, Nuñez F, Smith TL, Miller AN. Nonsteroidal anti-inflammatory drugs and bone-healing: a systematic review of research quality. JBJS Rev. 2016;4(3). https://doi.org/10.2106/JBJS.RVW.O.00055. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JPA, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate...

References : The effect of non-steroidal anti-infl...

Salari P, Abdollahi M. Controversial effects of non-steroidal anti-inflammatory drugs on bone: a review. Inflamm Allergy Drug Targets. 2009;8(3):169–75. Boursinos LA, Karachalios T, Poultsides L, Malizos KN. Do steroids, conventional non-steroidal anti-inflammatory drugs and selective Cox-2 inhibitors adversely affect fracture healing? J Musculoskelet Neuronal Interact. 2009;9(1):44–52. Kaly...

Abbreviations : The effect of non-steroidal anti-i...

Cyclooxygenase Non-steroidal anti-inflammatory drug/s Prostaglandin Prostaglandin E2

Conclusions : The effect of non-steroidal anti-inf...

The analgesic and therapeutic effects of NSAIDs are achieved by COX-2 inhibition [4]. It is likely that COX inhibition by NSAIDs is detrimental to the bone healing process, given the favourable actions of PG on this process [4]. Osteoblasts have the capacity to produce PGs, where PGE2 is most abundant, through the COX pathway though the evidence asserting that PGs have a direct role in bone healin...

Review : The effect of non-steroidal anti-inflamma...

The majority of the included studies revealed a high risk of bias, and conclusions from studies that have a high risk of bias are sufficient to affect interpretation of data [16,17,18]. Publication and selection bias is apparent in several included studies, as the negative effects of NSAIDs on osseointegration can be expected in the studies that administered NSAID at a high concentration and/or fo...

Review : The effect of non-steroidal anti-inflamma...

The influence of NSAIDS on bone healing in animal models has been shown to be related to the duration of treatment and drug selectivity [5]. A total of seven studies were identified that investigated the effect of NSAIDs on the osseointegration of titanium implants in animals: mice, rabbits, and rats (Table 8). The duration of treatment is a factor to consider when using NSAIDs, and a study cond...

Review : The effect of non-steroidal anti-inflamma...

The effects of NSAIDs on the osteogenic activity of osteoblasts have been extensively studied at the molecular pharmacological level [23]. However, only two studies have been identified that investigated the effect of NSAIDs on osteoblasts attached to titanium surfaces (Table 6). In the study conducted by Boyan et al., their results demonstrated that a non-selective COX inhibitor (indomethacin, 0...

Review : The effect of non-steroidal anti-inflamma...

The eligibility and study selection criteria as mentioned above were applied to the 79 full-text articles. A total of 66 studies were excluded after a full-text assessment for the following reasons: The study did not explore the role of COX pathway in osseointegration (n = 26). The effects of NSAIDs on osteoblasts were not investigated on titanium (n = 24). The study was a systematic re...

Review : The effect of non-steroidal anti-inflamma...

The full-text manuscripts of included studies were catalogued into in vitro, clinical, and in vivo studies. The data from the included studies were independently extracted by the primary (JDL) and the second reviewer (TJ) according to the “Data items” section as listed below. Disagreements or uncertainties were discussed with the third reviewer (MN) until an agreement was reached. The data co...

Review : The effect of non-steroidal anti-inflamma...

An electronic search into four databases: Ovid, Pubmed, Scopus, and Web of Science was performed to systematically identify the available literature. Articles published between January 1, 1999, and July 7, 2018, were considered. The focus question, used to guide the search strategy, according to the PICO schema is “Will variables such as the dosage, duration of administration, and selectivity o...

Review : The effect of non-steroidal anti-inflamma...

Cyclooxygenases have an important role in the production of PGs where these enzymes in bone tissues show increased activity under the influence of hypoxia-inducible factors [6, 11]. Therefore, local activity of COX enzymes promotes bone formation and resorption through the production of PGs [12]. Non-selective NSAIDs are reported to inhibit the activity of COX-1 equally, if not more than COX-2 [2]...

Review : The effect of non-steroidal anti-inflamma...

Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of drugs with anti-inflammatory, analgesic, and antipyretic effects. They are commonly used in dentistry for management of dental pain associated with inflammation. NSAIDs exert their effects through the inhibition of the cyclooxygenase (COX) enzyme, therefore interfering with the synthesis of prostaglandins (PG) and thromboxanes; PGs and ...

Abstract : The effect of non-steroidal anti-inflam...

Non-steroidal anti-inflammatory drugs are commonly used in implant dentistry for management of post-operative pain. The objective of this systematic review was to analyse the effect of non-steroidal anti-inflammatory drugs on the osteogenic activity of osteoblasts with an emphasis on its effect on osseointegration. A systematic literature search for in vitro, animal models, and clinical trials was...

Fig. 2. a Radiographic image of a 3.5-mm-wide by 7...

Fig. 2. a Radiographic image of a 3.5-mm-wide by 7-mm-length dental implant at the time of its placement at the mandibular left second premolar in a 63-year-old Caucasian female. b Radiographic image of a three-unit fixed partial denture upon its initial placement. The dental implant is the anterior abutment with the prosthesis screw retained to it. The distal abutment is the mandibular left sec...

Fig. 1. a Initial radiograph exposed at abutment i...

Fig. 1. a Initial radiograph exposed at abutment installation on a 5-mm-wide by 7-mm-length dental implant used to help support a removable partial denture for a 71-year-old Caucasian male. b Radiograph of the area taken at 82 months demonstrates good bone stability. c Clinical image of the area 82 months later. Soft tissue remains healthy. The two teeth anterior are in the process of receivin...

Table 5 Resonance frequency analysis : A 1–7 ye...

Time ISQ n Implant insertion 73.6 ± 8.1 86 1–4 weeks ...

Table 4 Implant survival, life table analysis : A ...

Interval Implants Failed Not followed CSR (%) Insertion to 1 year ...

Table 3 Specification of failed implants (three im...

Sex Age Smoker Risk factors Position Implant diameter ...

Table 2 Implant and site-related specifications : ...

  Number Percent Jaw Maxilla 60 69.8 Mandible ...

Table 1 Patient demographics : A 1–7 year retro...

  Number Percent Age (years) 20–29 1 1.3 30–39 ...

About this article : A 1–7 year retrospective f...

Rosen, P.S., Sahlin, H., Seemann, R. et al. A 1–7 year retrospective follow-up on consecutively placed 7-mm-long dental implants with an electrowetted surface. Int J Implant Dent 4, 24 (2018). https://doi.org/10.1186/s40729-018-0136-4 Download citation Received: 08 January 2018 Accepted: 21 May 2018 Published: 23 August 2018 DOI: https://doi.org/10.1186/s40729-018-0136...

Rights and permissions : A 1–7 year retrospecti...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : A 1–7 year retrospective ...

The study was performed in compliance with the Declaration of Helsinki. Data collection was performed in such a manner that subjects could not be identified, and therefore, it was exempt from IRB review according to Federal Regulation 45 CFR 46.101(b). All participants consented to publish their information details through the clinic’s standard patient consent procedure. Also, all images appear...

Author information : A 1–7 year retrospective f...

Clinical Professor of Periodontics, Baltimore College of Dental Surgery, University of Maryland Dental School, Baltimore, MD, USA Paul S. Rosen Private Practice limited to Periodontics and Dental Implants, 907 Floral Vale Boulevard, Yardley, PA, 19067, USA Paul S. Rosen Neoss Ltd, Gothenburg, Sweden Herman Sahlin University Clinic of Craniofacial, Maxillofacial and Oral Surgery, Vienna, Aust...

Availability of data and materials : A 1–7 year...

Due to the ethical and legal responsibility to respect participants’ rights to privacy and to protect their identity, the clinical dataset is not made publicly available.

References : A 1–7 year retrospective follow-up...

Srinivasan M, Vazquez L, Rieder P, Moraguez O, Bernard JP, Belser UC. Survival rates of short (6 mm) micro-rough surface implants: a review of literature and meta-analysis. Clin Oral Implants Res. 2014;25(5):539–45. Chrcanovic BR, Albrektsson T, Wennerberg A. Diabetes and oral implant failure: a systematic review. J Dent Res. 2014;93(9):859–67. Giro G, Chambrone L, Goldstein A, Rodrigues JA,...

References : A 1–7 year retrospective follow-up...

Jemt T, Olsson M, Franke SV. Incidence of first implant failure: a retroprospective study of 27 years of implant operations at one specialist clinic. Clin Implant Dent Relat Res. 2015;17(Suppl 2):e501–10. Pommer B, Frantal S, Willer J, Posch M, Watzek G, Tepper G. Impact of dental implant length on early failure rates: a meta-analysis of observational studies. J Clin Periodontol. 2011;38(9):856...

Abbreviations : A 1–7 year retrospective follow...

Cumulative survival rate Implant stability quotient Insertion torque Odds ratio Resonance frequency analysis Relative risk

Conclusion : A 1–7 year retrospective follow-up...

The current retrospective consecutive case series study provides preliminary data that treatment with 7-mm-length short implants with a hydrophilic electrowetted surface is a reasonable approach in sites with limited vertical bone dimension. It adds to the body of evidence supporting short implant use for compromised sites. The success seen might be attributed to the larger implant diameters that ...

Discussion : A 1–7 year retrospective follow-up...

Thirty-six percent of the implants in the study were placed in extraction sockets. Provided that sufficient initial implant stability is achieved, there should be no additional risk factors compared to implants in healed sites. Studies have shown no difference in marginal bone remodeling between immediately placed and delayed implants [15]. The biggest limitation of the current study is its very ...

Discussion : A 1–7 year retrospective follow-up...

A wide distribution in implant insertion torque (10–50 Ncm) was seen in the study. This reflects the variety of clinical situations in which the implants were placed. Assessments were made by using both the RFA value and the insertion torque as to first whether an implant should have been left to heal in the first place and if so, how this would be best accomplished, i.e., through its submergen...

Discussion : A 1–7 year retrospective follow-up...

This retrospective study is the first to look at short dental implants with a hydrophilic electrowetted surface. The survival data suggest that this treatment is a viable option to care. In a systematic review that identified 13 studies on implants shorter than 10 mm, the CSR from the individual studies ranged from 80 to 100% with a combined CSR of 98.3% after 5 years, 94.8% after 6 years, and ...

Results : A 1–7 year retrospective follow-up on...

The chart review identified 86 placed implants in 75 patients. Table 1 summarizes the patient demographics of the 75 patients. Patients ranged in age from 29 to 88 years with a mean of 61.0 ± 12.5 years. Twenty-seven of the patients were males and 48 were females. Table 2 summarizes the implant and site-related information of the 86 placed implants. Mean insertion torque was 30.1 ± 7...

Methods : A 1–7 year retrospective follow-up on...

Baseline parameters, both patient- and implant-related, as well as follow-up parameters (implant survival, follow-up time, and resonance frequency analysis) were collected from a review of the patient records. The main study parameters (principal outcome parameters) were defined to be implant loss and follow-up time. The cumulative survival rate was estimated. The influence of several factors on ...

Methods : A 1–7 year retrospective follow-up on...

A retrospective study on short 7 mm hydrophilic implants from a single center was conducted in a private practice limited to periodontics and surgical dental implant placements from one of the authors, PSR (Yardley, Pennsylvania, USA). An exhaustive chart review identified 75 patients for analysis that were treated with 86 short (7 mm) implants during a 5-year period (September 1, 2009, to Novem...

Background : A 1–7 year retrospective follow-up...

The aim of this retrospective consecutive case series study was to investigate implant survival rate and analyze possible factors affecting the survival of short implants placed in one surgical practice focused on implantology and periodontology in a temporal cohort.

Background : A 1–7 year retrospective follow-up...

In the past decades, the osseointegration rate of dental implants has dramatically increased, particularly in sites of softer dental bone, which may be attributed to the introduction of moderately roughened surfaces [1, 2]. Moreover, because of this increase in success, clinicians have attempted to push the envelope and place implants into sites that may provide a greater challenge as they wish to...

Abstract : A 1–7 year retrospective follow-up o...

This retrospective consecutive case series study was performed to determinate the survival rate and implant stability of short (7 mm length) dental implants with an electrowetted hydrophilic surface that were in function from 1 to 7 years. A retrospective chart review identified and evaluated 86 consecutively placed 7-mm-long dental implants (ProActive, Neoss Ltd., Harrogate, England) in 75 pat...

Fig. 5. Box plot illustrating maximum PD reduction...

Fig. 5. Box plot illustrating maximum PD reduction between the grafted and non-grafted patient groups that did not reach a significant difference (p = 0.968) Fig. 5. Box plot illustrating maximum PD reduction between the grafted and non-grafted patient groups that did not reach a significant difference (p = 0.968)

Fig. 4. Box plot presenting mean BOP reduction bet...

Fig. 4. Box plot presenting mean BOP reduction between the two patient groups (grafted and non-grafted) with no significant difference (p = 0.778) Fig. 4. Box plot presenting mean BOP reduction between the two patient groups (grafted and non-grafted) with no significant difference (p = 0.778)

Fig. 3. Dumbbell—dot plots illustrating (a) dise...

Fig. 3. Dumbbell—dot plots illustrating (a) disease resolution and no resolution at non-grafted and grafted sites at the patient level analysis with no significant difference between the two groups (p = 0.579). Patents with improvement, deterioration, and no improvement following the treatment based on the max PD changes are depicted; (b) disease resolution and no resolution at the implant...

Fig. 2. Box plot depicting no significant differen...

Fig. 2. Box plot depicting no significant differences of the baseline maximum PD values between the grafted and non-grafted patient groups (p = 0.353) Fig. 2. Box plot depicting no significant differences of the baseline maximum PD values between the grafted and non-grafted patient groups (p = 0.353)

Fig. 1. Combined surgical therapy of peri-implanti...

Fig. 1. Combined surgical therapy of peri-implantitis at respective defect sites: class I: intrabony component showing either a buccal dehiscency with a semicircular component (Ib) or a buccal dehiscency with a cicumferential component (Ic). Class II: supracrestal component. The red rectangles indicate the surface areas undergoing an implantoplasty, while the green areas indicate the defect area...

Table 4 Reduction of maximum PD (mm) : Clinical ou...

Group Patient level Implant level Mean SD Median ...

Table 3 Reduction of mean BOP (%) : Clinical outco...

Group Patient level Implant level mean SD median ...

Table 2 Disease resolution between the non-grafted...

  Non-grafted sites Grafted sites Total Patient level 7/29 (24.1%) 4/10 (40%) ...

Table 1 Implant site characteristics : Clinical ou...

  Non-grafted sites Grafted sites Implant number 41 16 Maxilla/mandible ...

About this article : Clinical outcomes following s...

Ramanauskaite, A., Becker, K., Juodzbalys, G. et al. Clinical outcomes following surgical treatment of peri-implantitis at grafted and non-grafted implant sites: a retrospective analysis. Int J Implant Dent 4, 27 (2018). https://doi.org/10.1186/s40729-018-0135-5 Download citation Received: 28 November 2017 Accepted: 21 May 2018 Published: 09 August 2018 DOI: https://doi.o...

Rights and permissions : Clinical outcomes followi...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Clinical outcomes following ...

The study protocol was approved by the Heinrich-Heine University (Düsseldorf, Germany) ethics committee. Ausra Ramanauskaite, Kathrin Becker, Gintaras Juodzbalys, and Frank Schwarz declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Clinical outcomes following s...

Department of Oral Surgery, Westdeutsche Kieferklinik, Universitätsklinikum Düsseldorf, D-40225, Düsseldorf, Germany Ausra Ramanauskaite Clinic of Dental and Oral Pathology, Lithuanian University of Health Sciences, Kaunas, Lithuania Ausra Ramanauskaite Department of Orthodontics, Westdeutsche Kieferklinik, Universitätsklinikum Düsseldorf, D-40225, Düsseldorf, Germany Kathrin Becker De...

Funding : Clinical outcomes following surgical tre...

The study was self-funded by the authors’ own departments.

References : Clinical outcomes following surgical ...

Download references

References : Clinical outcomes following surgical ...

Carcuac O, Derks J, Abrahamsson I, Wennström JL, Petzold M, Berglundh T. Surgical treatment of peri-implantitis. 3-year results from a randomized controlled clinical trial. J Clin Periodontol. 2017;44(12):1294–303. Canullo L, Peñarrocha-Oltra D, Covani U, Botticelli D, Serino G, Penarrocha M. Clinical and microbiological findings in patients with peri-implantitis: a cross-sectional study. Cli...

References : Clinical outcomes following surgical ...

Lindhe J, Meyle J, Working Group D of European Workshop on Periodontology. Peri-implant diseases: Consensus Report of the Sixth European Workshop on Periodontology. J Clin Periodontol. 2008;35(Suppl 8):282–5. Lang NP, Berglundh T, Working Group 4 of Seventh European Workshop on Periodontology. Periimplant diseases: where are we now?--Consensus of the Seventh European Workshop on Periodontology....

Conclusions : Clinical outcomes following surgical...

Within the limitations of the current study, it was concluded that the effectiveness of combined surgical therapy of peri-implantitis was comparable at both grafted and non-grafted implant sites and was not influenced by the initial bone-grafting procedures.

Discussion : Clinical outcomes following surgical ...

The further evaluation of maximum PD reduction did not indicate a significant difference between the two groups (i.e., grafted vs. non-grafted), with the range of 1.57 to 2.20 mm at the patient level analysis and 1.31 to 2.10 mm at the implant level. These results are in concurrence with data from the previous studies, where mean PD reduction amounted from 0.74 to 2.55 mm [16], up to 3 [18], an...

Discussion : Clinical outcomes following surgical ...

According to the eighth European Workshop of Periodontology (EFP), evaluation of the effectiveness of different peri-implantitis therapies should be based on a composite outcome of disease resolution, including resolutions of mucosal inflammation, reductions in probing pocket depths, and no further bone loss [3]. The current retrospective clinical investigation evaluated treatment outcomes follow...

Results : Clinical outcomes following surgical tre...

At the implant level, BOP reduction was noted to be 74.96% (minimum 0%; maximum 100%) at grafted implant sites and 54.88% (minimum 0%; maximum 100%) at non-grafted implant sites. According to the results of the chi-square test, the mean BOP reduction did not differ significantly between the groups at either the patient (p = 0.778, df = 1, χ2 = 0.079) or the implant (p = 0.515, df...

Results : Clinical outcomes following surgical tre...

The present analysis was based on 39 patients diagnosed with peri-implantitis in 57 implants. The patients were divided into 2 groups according to the grafting of the site: non-grafted implant sites (29 patients/41 implants) and grafted implant sites (10 patients/16 implants). The characteristics of the implant sites are presented in Table 1. In total, 26 implants (45.6%) were located in the max...

Methods : Clinical outcomes following surgical tre...

For all patients, the following clinical parameters were available: BOP (as measured within 60 s after probing) and PD (as measured in millimeters from the mucosal margin to the bottom of the probeable pocket). BOP and PD were assessed at six aspects around the implant: mesio-buccal, mid-buccal, disto-buccal, mesio-oral, mid-oral, and disto-oral. Maximum PD values (max PD) and mean BOP scores wer...

Methods : Clinical outcomes following surgical tre...

Peri-implantitis was defined as bleeding on probing (BOP) with or without suppuration (Supp) in addition to changes in the radiographic bone level. Interproximal bone level changes were estimated on intraoral radiographs. In the absence of available baseline radiographs taken at prosthesis installation, “a threshold vertical distance of 2 mm from the expected marginal bone level” was used to a...

Methods : Clinical outcomes following surgical tre...

For this retrospective analysis, standardized clinical record forms of a total of 39 partially/fully edentulous patients (25 female and 12 male) exhibiting 57 implants were screened. All patients had attended the Department of Oral Surgery, Heinrich Heine University, Düsseldorf, Germany for the treatment of peri-implantitis between 2007 and 2010, and were under regular implant maintenance care. T...

Background : Clinical outcomes following surgical ...

Peri-implantitis is caused by a bacterial challenge and characterized by inflammation in the peri-implant soft tissues and a progressive loss of supporting bone [1, 2]. Consequently, its treatment is cause-related and primarily aimed at arresting disease progression [3]. Based on the currently available evidence, non-surgical mechanical debridement alone seems to have a limited efficacy for the m...

Abstract : Clinical outcomes following surgical tr...

This retrospective analysis aimed at comparing the clinical outcomes following combined surgical therapy of peri-implantitis at initially grafted and non-grafted (i.e., pristine) implant sites. A total of 39 patients exhibiting 57 implants diagnosed with peri-implantitis (i.e., 16 implants at grafted and 41 implants at non-grafted sites) were included. Each subject had received a combined (i.e., ...

Fig. 6. Funnel plot for anchorage loss in the vert...

Fig. 6. Funnel plot for anchorage loss in the vertical dimension (MD mean difference, SE standard error) Fig. 6. Funnel plot for anchorage loss in the vertical dimension (MD mean difference, SE standard error)

Fig. 5. Funnel plot for anchorage loss in the hori...

Fig. 5. Funnel plot for anchorage loss in the horizontal dimension (MD mean difference, SE standard error) Fig. 5. Funnel plot for anchorage loss in the horizontal dimension (MD mean difference, SE standard error)

Fig. 4. Forest plot for anchorage loss in the vert...

Fig. 4. Forest plot for anchorage loss in the vertical dimension Fig. 4. Forest plot for anchorage loss in the vertical dimension

Fig. 3. Forest plot for anchorage loss in the hori...

Fig. 3. Forest plot for anchorage loss in the horizontal dimension Fig. 3. Forest plot for anchorage loss in the horizontal dimension

Fig. 2. Graphic visualization of the risk of bias ...

Fig. 2. Graphic visualization of the risk of bias judgements Fig. 2. Graphic visualization of the risk of bias judgements

Fig. 1. PRISMA study flow diagram : Efficacy of or...

Fig. 1. PRISMA study flow diagram Fig. 1. PRISMA study flow diagram

Table 3 Risk of bias judgment according to the Coc...

NoneTable 3 Risk of bias judgment according to the Cochrane Collaboration

Table 2 Characteristics of the included studies (T...

Reference Number of patients Type of study (RCT/CCT/other) Control intervention Type of implant (length, material) ...

Table 1 List of excluded studies (with reason) (Of...

Reference Reason for exclusion Barros et al. (2017) [3] Anchorage loss at first molar not specified Borsos et al. (2012) [7]...

About this article : Efficacy of orthodontic mini ...

Becker, K., Pliska, A., Busch, C. et al. Efficacy of orthodontic mini implants for en masse retraction in the maxilla: a systematic review and meta-analysis. Int J Implant Dent 4, 35 (2018). https://doi.org/10.1186/s40729-018-0144-4 Download citation Received: 04 May 2018 Accepted: 27 August 2018 Published: 25 October 2018 DOI: https://doi.org/10.1186/s40729-018-0144-4

Rights and permissions : Efficacy of orthodontic m...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Additional file : Efficacy of orthodontic mini imp...

Data extraction template. (CSV 2 kb)

Ethics declarations : Efficacy of orthodontic mini...

Not applicable Not applicable Kathrin Becker, Annika Pliska, Caroline Busch, Benedict Wilmes, Michael Wolf, and Dieter Drescher declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Efficacy of orthodontic mini ...

Correspondence to Kathrin Becker.

Author information : Efficacy of orthodontic mini ...

Michael Wolf and Dieter Drescher contributed equally to this work. Department of Orthodontics, Universitätsklinikum Düsseldorf, 40225, Düsseldorf, Germany Kathrin Becker, Annika Pliska, Caroline Busch, Benedict Wilmes & Dieter Drescher Department of Orthodontics, Universitätsklinikum RWTH Aachen, Aachen, Germany Michael Wolf You can also search for this author in ...

Acknowledgements : Efficacy of orthodontic mini im...

We acknowledge the work of S. Moscarino, E. Burceck, and J. Bartz who assisted in the abstract screening and hand searching. The study was self-funded by the authors. The data extracted for the meta-analysis are available in the Additional file 1.

References : Efficacy of orthodontic mini implants...

Xun CL, Zeng XL, Wang X. Clinical application of miniscrew implant for maximum anchorage cases. Zhonghua Kou Qiang Yi Xue Za Zhi. 2004;39(6):505–8. Yao CC, Lai EH, Chang JZ, Chen I, Chen YJ. Comparison of treatment outcomes between skeletal anchorage and extraoral anchorage in adults with maxillary dentoalveolar protrusion. Am J Orthod Dento Orthoped. 2008;134(5):615–24. Download references ...

References : Efficacy of orthodontic mini implants...

Upadhyay M, Yadav S, Patil S. Mini-implant anchorage for en-masse retraction of maxillary anterior teeth: a clinical cephalometric study. Am J Orthod Dentofac Orthop. 2008b;134(6):803–10. Upadhyay M, Yadav S, Nagaraj K, Uribe F, Nanda R. Mini-implants vs fixed functional appliances for treatment of young adult Class II female patients: a prospective clinical trial. Angle Orthod. 2012;82(2):294...

References : Efficacy of orthodontic mini implants...

Nienkemper M, Wilmes B, Pauls A, Drescher D. Impact of mini-implant length on stability at the initial healing period: a controlled clinical study. Head Face Med. 2013;9:30. Papageorgiou SN, Zogakis IP, Papadopoulos MA. Failure rates and associated risk factors of orthodontic miniscrew implants: a meta-analysis. Am J Orthod Dentofac Orthop. 2012;142(5):577–595.e577. Park HS, Kwon TG, Sung JH. ...

References : Efficacy of orthodontic mini implants...

Kawa D, Kunkel M, Heuser L, Jung BA. What is the best position for palatal implants? A CBCT study on bone volume in the growing maxilla. Clin Oral Investig. 2017;21(2):541–9. Kuhlberg AJ, Burstone CJ. T-loop position and anchorage control. Am J Orthod Dentofac Orthop. 1997;112(1):12–8. Kuhlberg AJ, Priebe DN. Space closure and anchorage control. Semin Orthod. 2001;7(1):42–9. Kuroda S, Yam...

References : Efficacy of orthodontic mini implants...

de Almeida MR, Herrero F, Fattal A, Davoody AR, Nanda R, Uribe F. A comparative anchorage control study between conventional and self-ligating bracket systems using differential moments. Angle Orthod. 2013;83(6):937–42. Durrani OK, Shaheed S, Khan A, Bashir U. Comparison of in-vivo failure of single-thread and dualthread temporary anchorage devices over 18 months: A split-mouth randomized contr...

References : Efficacy of orthodontic mini implants...

Al-Sibaie S, Hajeer MY. Assessment of changes following en-masse retraction with mini-implants anchorage compared to two-step retraction with conventional anchorage in patients with class II division 1 malocclusion: a randomized controlled trial. Eur J Orthod. 2014;36(3):275–83. Alharbi F, Almuzian M, Bearn D. Miniscrews failure rate in orthodontics: systematic review and meta-analysis. Eur J O...

Conclusions : Efficacy of orthodontic mini implant...

The present systematic review and meta-analysis revealed that orthodontic mini implants are associated with a significantly lower anchorage loss at the first upper molars compared to conventional anchorage devices for en-masse retraction in the maxilla. However, the ideal implant location (anterior palate versus alveolar ridge) and the most beneficial concept (direct or indirect anchorage) need t...

Discussion : Efficacy of orthodontic mini implants...

Indirect anchorage through implants in the alveolar ridge was associated with mesial molar migration in all studies included in the present review [5, 9, 54, 57]. Nonetheless, anchorage loss with indirect anchorage was significantly lower compared to the conventional devices [5, 9, 57]. It has been suggested that the anchorage loss at indirectly anchored mid-palatal implants may be caused by a sli...

Discussion : Efficacy of orthodontic mini implants...

The present systematic review was conducted to address the following focused question: “In patients with a need for en masse retraction of the upper front teeth, what is the efficacy of orthodontic mini implants for anchorage control compared with conventional anchorage devices?” The literature search revealed that efficacy of anchorage control of orthodontic mini implants in comparison to co...

Results : Efficacy of orthodontic mini implants fo...

Meta-analysis was performed on RCTs reporting on anchorage loss at the first molar. Based on seven studies [1, 4, 11, 28, 49, 50, 52], the weighted mean differences (WMD) [95% CI, p] in horizontal anchorage loss between test and control groups amounted up to − 2.79 mm [− 3.56 to − 2.03 mm, p 

Results : Efficacy of orthodontic mini implants fo...

The overall success rates of the orthodontic mini implants varied among the studies. A success rate of 95.7% with a loss of 2 from 46 implants was reported by Upadhyay et al. [48], and the implants could be replaced immediately. Two patients developed a peri-implant inflammation which was resolved through improved oral hygiene. A loss of 5 of 72 implants was reported by Upadhyay et al. [49], and i...

Results : Efficacy of orthodontic mini implants fo...

In detail, anchorage loss associated with indirect anchorage and a mid-palatal implant amounted to 1.5 ± 2.6 mm versus 3 ± 3.4 mm [5], 0.7 ± 0.4 (right molar) and 1.1 ± 0.3 mm (left molar) [54], 1.73 ± 0.39 mm (horseshoe), and 0.36 ± 0.11 mm (posterior reinforcement) versus 4.21 ± 1.17 mm [57]. An anchorage loss of 0.2 ± 0.35 mm versus 2.0 mm ± ...

Results : Efficacy of orthodontic mini implants fo...

The study samples considered for the qualitative synthesis consisted of females exhibiting Angle Class II,1 malocclusion with upper dental protrusion and an overjet of at least 7 mm [48], patients with a dental Class II, a need for extraction of the first upper premolars and front retraction [54], or Class III patients with a need for pre-surgical decompensation through premolar extraction and fr...

Results : Efficacy of orthodontic mini implants fo...

The search for the review was undertaken at December 31, 2017. A total of 2046 potentially relevant titles and abstracts were found during the electronic and manual search (676 after duplicate removal) of which 99 titles were considered relevant for abstract screening. During the first stage of study selection, 58 publications were excluded based on the abstract. For the second phase, the complete...

Methods : Efficacy of orthodontic mini implants fo...

When data were not available in the printed report, we calculated the missing information whenever possible (e.g., by subtracting pre- and post en masse retraction values). In cases where a zero variance (0.00 mm) was presented in the summary tables, these values were changed to 0.01 mm to enable meta-analysis. The corresponding authors of the published studies were contacted when needed. Heter...

Methods : Efficacy of orthodontic mini implants fo...

Inclusion of less than five patients Lack of clinical data on anchorage loss Measurement of anchorage loss not by superimposition of lateral cephalograms or superimposition of study casts Previous orthodontic treatment Treatment in control group not specified Inclusion of diseased patients, e.g., patients with systemic diseases, periodontal disease, and syndromes Other treatment than en mass...

Methods : Efficacy of orthodontic mini implants fo...

AND (“anchorage loss” OR “anchorage quality” OR “quality of life” OR “benefit” or “harm” OR “efficacy” OR “side effects” OR “effect” OR “orthodontic anchorage procedures”[mh] OR “treatment outcome”[mh]) Search terms EMBASE (including EMTREE terms) (“en-masse retraction” OR “incisor retraction” OR “front retraction” OR “orthodontic gap clo...

Methods : Efficacy of orthodontic mini implants fo...

This systematic review was structured and conducted according to the preferred reporting items of the PRISMA statement [34]. The focused question serving for literature search was structured according to the PICO (Patients, Intervention, Control, Outcome) format: “In patients with a need for en masse retraction of the upper front teeth, what is the efficacy of orthodontic mini implants for anch...

Review : Efficacy of orthodontic mini implants for...

Extraction of the permanent teeth for retraction of the protruded front teeth is a routine approach in orthodontics. Various techniques such as headgear, Nance button, and transpalatal arches (TPA) have been proposed to achieve sufficient anchorage [5, 8, 9, 12, 28, 31, 45]. Nevertheless, anchorage control turned out to be highly demanding as the conventional approaches were commonly associated wi...

Abstract : Efficacy of orthodontic mini implants f...

Retraction of the upper incisors/canines requires maximum anchorage. The aim of the present study was to analyze the efficacy of mini implants in comparison to conventional devices in patients with need for en masse retraction of the front teeth in the upper jaw. An electronic search of PubMed, Web of Science, and EMBASE and hand searching were performed. Relevant articles were assessed, and data...

Fig. 8. PPD on natural teeth. No significant diffe...

Fig. 8. PPD on natural teeth. No significant differences appreciable Fig. 8. PPD on natural teeth. No significant differences appreciable

Fig. 7. PPD on dental implants. No significant dif...

Fig. 7. PPD on dental implants. No significant differences appreciable Fig. 7. PPD on dental implants. No significant differences appreciable

Fig. 6. BoP on natural teeth. While the control gr...

between 1 month and 3 months, the test group values decrease during all the duration of the study Fig. 6. BoP on natural teeth. While the control group shows a mild increase between 1 month and 3 months, the test group values decrease during all the duration of the study

Fig. 5. BoP on dental implants. It can be observed...

Fig. 5. BoP on dental implants. It can be observed how the values keep decreasing after 1 month only in the test group Fig. 5. BoP on dental implants. It can be observed how the values keep decreasing after 1 month only in the test group

Fig. 4. PI on natural teeth. After 1 month, the t...

Fig. 4. PI on natural teeth. After 1 month, the test group showed mild reduction while control a light improvement Fig. 4. PI on natural teeth. After 1 month, the test group showed mild reduction while control a light improvement

Fig. 3. PI on dental implants. Test values keep re...

Fig. 3. PI on dental implants. Test values keep reducing after 1 month while control maintains the same level Fig. 3. PI on dental implants. Test values keep reducing after 1 month while control maintains the same level

Fig. 2. Patients’ population flow chart : Effect...

Fig. 2. Patients’ population flow chart Fig. 2. Patients’ population flow chart

Fig. 1. Electric toothbrush heads: on the left is ...

Fig. 1. Electric toothbrush heads: on the left is the one designed for natural teeth, and on the right is the one designed for dental implants Fig. 1. Electric toothbrush heads: on the left is the one designed for natural teeth, and on the right is the one designed for dental implants

Table 1 BoP, PI, and PPD mean values at baseline, ...

  Baseline 1 month 3 months T0 T1 T2 BoP implants, t...

About this article : Effectiveness and compliance ...

Allocca, G., Pudylyk, D., Signorino, F. et al. Effectiveness and compliance of an oscillating-rotating toothbrush in patients with dental implants: a randomized clinical trial. Int J Implant Dent 4, 38 (2018). https://doi.org/10.1186/s40729-018-0150-6 Download citation Received: 12 April 2018 Accepted: 24 October 2018 Published: 10 December 2018 DOI: https://doi.org/10.11...

Rights and permissions : Effectiveness and complia...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Effectiveness and compliance...

Not applicable This study was conducted in compliance with the principles of the Declaration of Helsinki, and the approval of the ethics committee required for the study was obtained from the Ethics Committee of the IRCCS Ospedale Maggiore Policlinico di Milano, Fondazione Ca’ Granda. The procedures to be performed were explained in detail, and the patients signed the consent form. Not applica...

Author information : Effectiveness and compliance ...

Center for Edentulism and Jaw Atrophies, Maxillofacial Surgery and Dentistry Unit, Fondazione IRCCS Cà Granda – Ospedale Maggiore Policlinico, University of Milan, Via Commenda 10, 20122, Milan, Italy Giuseppe Allocca, Diana Pudylyk, Fabrizio Signorino & Carlo Maiorana Oral Surgery, Maxillofacial Surgery and Dentistry Unit, Fondazione IRCCS Cà Granda – Ospedale Maggiore Policlinico, Un...

Acknowledgements : Effectiveness and compliance of...

Not applicable The authors declare no funds for the research. Mean data of PI, BoP, and PPD collected from 80 periodontal charts are shown in Table 1.

References : Effectiveness and compliance of an os...

Download references

References : Effectiveness and compliance of an os...

Berglundh T, Lindhe J. Dimension of the periimplant mucosa. Biological width revisited. J Clin Periodontol. 1996;23(10):971–3 PubMed PMID: 8915028. Berglundh T, Lindhe J, Ericsson I, Marinello CP, Liljenberg B, Thomsen P. The soft tissue barrier at implants and teeth. Clin Oral Implants Res. 1991;2(2):81–90 PubMed PMID: 1809403. Berglundh T, Abrahamsson I, Welander M, Lang NP, Lindhe J. Morp...

References : Effectiveness and compliance of an os...

Quirynen M, De Soete M, van Steenberghe D. Infectious risks for oral implants: a review of the literature. Clin Oral Implants Res. 2002;13(1):1–19 PubMed PMID: 12005139. Roos-Jansåker AM, Renvert S, Egelberg J. Treatment of peri-implant infections: a literature review. J Clin Periodontol. 2003;30(6):467–85 PubMed PMID: 12795785. Ho HP, Niederman R. Effectiveness of the Sonicare sonic toothb...

References : Effectiveness and compliance of an os...

Pjetursson BE, Lang NP. Prosthetic treatment planning on the basis of scientific evidence. J Oral Rehabil. 2008;35(Suppl 1):72–9. https://doi.org/10.1111/j.1365-2842.2007.01824.x PubMed PMID: 18181936. Jung RE, Pjetursson BE, Glauser R, Zembic A, Zwahlen M, Lang NP. A systematic review of the 5-year survival and complication rates of implant-supported single crowns. Clin Oral Implants Res. 2008...

Abbreviations : Effectiveness and compliance of an...

Bleeding on probing Plaque index Pocket probing depth

Conclusion : Effectiveness and compliance of an os...

The oscillating-rotating toothbrush can be used for the plaque and bleeding control around both natural teeth and dental implants. It has also been shown how the toothbrush head designed for dental implant can be effective in plaque removing of the peri-implant tissues.

Discussion : Effectiveness and compliance of an os...

At the end of the present study, electric toothbrush groups showed plaque and bleeding values lower (PI and BoP on teeth) or at least without significative differences (BoP on implants) than the control group. These data may suggest how the use of electric toothbrush, associated to the dedicate heads, can be an effective method for plaque and bleeding reduction.

Discussion : Effectiveness and compliance of an os...

This 3-month study aimed to demonstrate the efficacy of an electric toothbrush in reducing plaque and gingival inflammation around dental implants and natural teeth. To better understand the different data collected around two different anatomical structures, we decided to collect data separately. Analyzing our results, it is possible to observe how the mean values for probing, bleeding, and plaqu...

Results : Effectiveness and compliance of an oscil...

The difference between the BoP recorded on dental implant sites at baseline and the end of the study showed statistical significance for both the test and control groups (P 

Results : Effectiveness and compliance of an oscil...

Seventy-eight patients successfully completed the study (45 women and 33 men aged from 31 to 76 years old) (Fig. 2). Two patients of test group did not show up both at the first and second controls. No patients were excluded or showed complications or adverse reaction. Results are shown in Table 1. The average number of implants per patients was 4.8 ± 3.4 in the control group and 4.4 ±...

Methods : Effectiveness and compliance of an oscil...

Mean scores of all clinical indices for each subject were calculated separately for dental implants and natural teeth. The final data analysis was performed for those subjects who completed the study. The Student’s t test and the Mann-Whitney U test were used to evaluate whether any statistically significant differences were present between the two groups at each time point, and the Wilcoxon sig...

Methods : Effectiveness and compliance of an oscil...

The study was conducted between September 2015 and June 2017 at Implantology Department of Policlinic Hospital, University of Milan, Milan. It was designed as a monocentric randomized clinical study according to the STROBE criteria. Eighty patients who underwent dental implant rehabilitation were selected for this study. At the screening visit, subjects were asked to read and sign a written inform...

Background : Effectiveness and compliance of an os...

Dental implants became one of the most accepted treatments for the rehabilitation of partial or complete edentulism [1]. However, inflammatory processes may still occur due to the presence of the implant itself [2]. It is well known that peri-mucositis and peri-implantitis are strictly related to the presence of plaque on the surface of the implant-prosthetic complex, which lead respectively to th...

Abstract : Effectiveness and compliance of an osci...

The aim of this randomized clinical trial was to assess the efficacy of an oscillating-rotating toothbrush in reducing plaque and inflammation around dental implants. Eighty patients presenting dental implants were enrolled in this study and assigned randomly to two different groups: 40 patients in the test group and 40 in the control one. Each patient in the test group received an oscillating-ro...

Fig. 2. The cumulative survival rates for the diff...

RFs (log rank, p = 0.006) Fig. 2. The cumulative survival rates for the different RF groups revealing a significant difference for patients without any and patients with local and systemic RFs (log rank, p = 0.006)

Fig. 1. On Kaplan-Meier survival estimates, the cu...

Fig. 1. On Kaplan-Meier survival estimates, the cumulative survival rate was 91.5% Fig. 1. On Kaplan-Meier survival estimates, the cumulative survival rate was 91.5%

Table 2 Clinical parameters and reason for implant...

Region Systemic RF Local RF Immediate procedure Bone grafting Time of failure (months...

Table 1 Distribution of patients with local and sy...

Systemic RF No. of implants (n = 31) No. of patients (n = 14) Local RF No. of implants (n = 100) ...

About this article : Retrospective cohort study of...

Saridakis, S.K., Wagner, W. & Noelken, R. Retrospective cohort study of a tapered implant with high primary stability in patients with local and systemic risk factors—7-year data. Int J Implant Dent 4, 41 (2018). https://doi.org/10.1186/s40729-018-0151-5 Download citation Received: 20 May 2018 Accepted: 24 October 2018 Published: 17 December 2018 DOI: https://doi.org/10...

Rights and permissions : Retrospective cohort stud...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Retrospective cohort study o...

This article contains data obtained during follow-up in a cohort of patients treated with a CE-certified implant in a University Medical Center. Since the product is already approved in accordance with the German Medical Devices Act, no additional ethics approval was not required for treatment. All procedures performed in studies involving human participants were in accordance with the ethical sta...

Author information : Retrospective cohort study of...

Department of Oral and Maxillofacial Surgery – Plastic Surgery, University Medical Center, Johannes Gutenberg University of Mainz, Augustusplatz 2, 55131, Mainz, Germany Sotirios Konstantinos Saridakis, Wilfried Wagner & Robert Noelken Private Practice for Oral Surgery, Lindau/Lake Constance, Germany Robert Noelken You can also search for this author in PubMed Go...

Acknowledgements : Retrospective cohort study of a...

Not applicable The work was supported by the Clinic of Oral and Maxillofacial Surgery, University Medical Center, Mainz. The dataset supporting the conclusions of this article is partially included within the article. The SPSS data can be given on demand of the editor.

References : Retrospective cohort study of a taper...

Schropp L, Isidor F, Kostopoulos L, Wenzel A. Patient experience of, and satisfaction with, delayed-immediate vs delayed single-tooth implant placement. Clin Oral Implants Res. 2004;15:498–503. Download references

References : Retrospective cohort study of a taper...

August M, Chung K, Chang Y, Glowacki J. Influence of estrogen status on endosseous implant osseointegration. J Oral Maxillofac Surg. 2001;59:1285–9. Hultin M, Gustafsson A, Hallstrom H, Johansson LA, Ekfeldt A, Klinge B. Microbiological findings and host response in patients with periimplantitis. Clin Oral Implants Res. 2002;13:349–58. Heitz-Mayfield LJA. Peri-implant diseases: diagnosis and...

References : Retrospective cohort study of a taper...

Chrcanovic BR, Albrektsson T, Wennerberg A. Diabetes and oral implant failure: a systematic review. J Dent Res. 2014;93(9):859–67. Balshi TJ, Wolfinger GJ. Dental implants in the diabetic patient: a retrospective study. Implant Dent. 1999;8:355–9. Fiorellini JP, Chen PK, Nevins M, Nevins ML. A retrospective study of dental implants in diabetic patients. Int J Periodontics Restorative Dent. 2...

References : Retrospective cohort study of a taper...

Kramer FJ, Baethge C, Swennen G, Bremer B, Schwestka-Polly R, Dempf R. Dental implants in patients with orofacial clefts: a long-term follow-up study. Int JOral Maxillofac Surg. 2005;34:715–21. Ortega-Martinez J, Perez-Pascual T, Mareque-Bueno S, Hernandez-Alfaro F, Ferres-Padro E. Immediate implants following tooth extraction. A systemic review. Med Oral Patol Oral Cir Bucal. 2012;17(2):e251...

References : Retrospective cohort study of a taper...

U.S. Census Bureau, 2012 Population Estimates and 2014 National Projections. [Zitiert:18.12.2014]. https://www.census.gov/data/tables/2014/demo/popproj/2014-summary-tables.html. Ikebe K, Wada M, Kagawa R, Maeda Y. Is old age a risk factor for dental implants? Jpn Dent Sci Rev. 2009;45:59–64. Hu SC, Lan CE. High-glucose environment disturbs the physiologic functions of keratinocytes: focusing o...

Conclusions : Retrospective cohort study of a tape...

This study was based on the recruitment of a quite heterogeneous group of patients treated with NobelActive implants, for the purpose of investigating the influence of local and systemic risk factors on implant survival and marginal bone levels. It can be considered that the presence of local or systemic risk factors does not influence implant survival whereas the combination of local and systemic...

Discussion : Retrospective cohort study of a taper...

A major weakness of the study is the relative small size of the group with systemic RFs (14 implants by 6 patients) as well as of the group with systematic and local RFs (17 implants by 6 patients). Because of the relative small size of the sample, this study can provide the basis for further investigations based on larger patient samples.

Discussion : Retrospective cohort study of a taper...

The survival rate for 93 implants in 45 patients with no RFs was 94.8%. Moraschini et al. [44] have exhibited in their systematic review, based on 7711 implants, similar SRs with cumulative mean values of 94.6%. Moreover, in the subcohort of our study, by 44 of the above 93, implants were performed immediate procedures (25 immediate implantations, 35 immediate restorations, 16 both of them) so the...

Discussion : Retrospective cohort study of a taper...

In one patient with three implants and long intake of corticosteroids against rheumatoid arthritis (7.5 mg prednisolone per day for at least 2 years), no complication was detected in our study. Long-term use of corticosteroids can also lead to implant failures, according to Wood and Vermilyea [34] by modifying the patient’s response to bacterial infection [35], but at the present time, there i...

Discussion : Retrospective cohort study of a taper...

Most implant studies deal only with local risk factors, although the existence of systemic risk factors plays a significant role to the implant survival. We use the NobelActive dental implant in this study in order to investigate if this promising implant with the special design could achieve better survival rates in difficult situations with several risk factors. The present study revealed no sta...

Results : Retrospective cohort study of a tapered ...

Regarding the implant shoulder level, the average interproximal marginal bone level was − 0.49 ± 0.83 mm (range, 0 to − 3.3 mm) at the mesial aspect and − 0.51 ± 0.82 mm (range, 0 to − 3.9 mm) at the distal aspect of the implants. When the marginal bone level was considered as a function of time, there was no strict correlation between the marginal bone status and th...

Results : Retrospective cohort study of a tapered ...

Ninety-eight patients with 207 implants complied with the treatment protocol attended the follow-up. During the follow-up period, 15 implants failed in 12 patients. Age and gender were not correlated with a lower implant survival. The implant losses occurred in a time range between 0.5 and 39 months following implant placement (mean 7.3 ± 11.1 months). The reasons for implant failure were ...

Material and methods : Retrospective cohort study ...

Subpopulations within the study group (immediate vs. delayed placement) were compared using the Wilcoxon-Mann-Whitney non-parametric U test. The reported p values were two sided. All calculations were carried out using SPSS for Mac, Version 22 (SPSS Inc., Chicago, IL, USA).

Material and methods : Retrospective cohort study ...

Preservation of all alveolar socket walls via longitudinal extraction after periotomy avoiding oro-vestibular luxation. Meticulous cleaning of the extraction site. Placement of rather long implants that allow for a high level of primary stability. Implant dimensions were as follows: implant length 8.5 mm, 24 implants; 10 mm, 6 implants; 11.5 mm, 64 implants; 13 mm, 80 implants; 15 mm, 31 i...

Material and methods : Retrospective cohort study ...

These patients received a total of 207 NobelActive implants (Nobel Biocare, Zurich, Switzerland) placed by two experienced surgeons. Between November 2011 and February 2015, 188 implants were placed in the maxilla, and 19 implants in the mandible. All implant placement procedures were conducted at the Department of Oral and Maxillofacial Surgery of the University Medical Center, Mainz, Germany. Fi...

Material and methods : Retrospective cohort study ...

One hundred and ten patients were invited for follow-up evaluation. All patients were treated in the period from 10/2008 to 02/2015 in the Clinic of Oral and Maxillofacial Surgery, University Medical Center Mainz. Inclusion criteria were as follows: implant placement of a NobelActive implant, study subjects over 18 years old, residual bone dimension in the edentulous region of at least 5 mm in h...

Introduction : Retrospective cohort study of a tap...

Primary stability is a prerequisite for successful osseointegration and remains the most significant factor for the survival of dental implants [16]. Therefore, current research focuses on amelioration of existing augmentation techniques and materials or on the development of new implants with self-tapping properties for improving bone contact as well for increasing primary stability. The aim of ...

Introduction : Retrospective cohort study of a tap...

Based on published demographic data, the median age of the world population constantly increases [1]. This has led to an increase in the number of dental implants inserted in senior individuals with local and systemic risk factors [2]. Nevertheless, despite numerous studies having been conducted on this topic, the results remain controversial, almost 50 years after the first dental implant placem...

Abstract : Retrospective cohort study of a tapered...

This retrospective study examined the mid- to long-term clinical and radiographic performance of a tapered implant in various treatment protocols in patients with local and systemic risk factors (RFs). Two hundred seven NobelActive implants were inserted in 98 patients in the period from 10/2008 to 02/2015. The subdivision of the cohort was defined by local (n = 40), systemic (n = 6), loc...

Fig. 4. Vestibular view of contralateral lateral i...

Fig. 4. Vestibular view of contralateral lateral incisor Fig. 4. Vestibular view of contralateral lateral incisor

Fig. 3. Vestibular view of right lateral implant s...

Fig. 3. Vestibular view of right lateral implant supported crown Fig. 3. Vestibular view of right lateral implant supported crown

Fig. 2. Probing of the peri-implant sulcus : Esthe...

Fig. 2. Probing of the peri-implant sulcus Fig. 2. Probing of the peri-implant sulcus

Fig. 1. a Pre-operative panoramic radiograph of th...

Fig. 1. a Pre-operative panoramic radiograph of the patient, (b) abutment in place, following the osseointegration period, (c) periapical radiograph at 1-year follow up, (d) final restoration at 1-year follow up, and (e) smile line Fig. 1. a Pre-operative panoramic radiograph of the patient, (b) abutment in place, following the osseointegration period, (c) periapical radiograph at 1-year foll...

Table 6 Spearman’s correlation test between smil...

  Smile line VAS Smile line Correlation coefficient 1 − .699a ...

Table 5 PES of patients with different smile lines...

PES result Smile line Low (n = 4) Medium (n = 10) High (n = 5) Poor (0–...

Table 4 Spearman’s correlation test between VAS ...

  PES WES VAS Spearman’s rho VAS Correlation coefficient ...

Table 3 Detailed results of pink and white estheti...

  Esthetic score 0 1 2 PES  Mesial papilla ...

Table 2 Esthetic scores, sub-classification of the...

  Number of patients Percentage Pink esthetic score  Poor (0–7) 2 10.5% ...

Table 1 Clinical features of the implants (Of: Est...

Implant site Biotype Smile line Placement timing PES WES ...

About this article : Esthetic evaluation of implan...

Altay, M.A., Sindel, A., Tezerişener, H.A. et al. Esthetic evaluation of implant-supported single crowns: a comparison of objective and patient-reported outcomes. Int J Implant Dent 5, 2 (2019). https://doi.org/10.1186/s40729-018-0153-3 Download citation Received: 25 July 2018 Accepted: 09 December 2018 Published: 07 January 2019 DOI: https://doi.org/10.1186/s40729-018-0...

Rights and permissions : Esthetic evaluation of im...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Esthetic evaluation of impla...

This study was approved by the Akdeniz University Ethical Review Board. All participants consented to publish their information details. Dr. Altay has provided consultancy for Checkpoint Surgical LLC in 2014. All other authors declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Esthetic evaluation of implan...

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Akdeniz University, Dumlupinar Boulevard, Campus, 07058, Antalya, Turkey Mehmet Ali Altay, Alper Sindel, Hüseyin Alican Tezerişener & Nelli Yıldırımyan Department of Prosthodontics, Faculty of Dentistry, Akdeniz University, Antalya, Turkey Mehmet Mustafa Özarslan You can also search for this author in ...

Acknowledgements : Esthetic evaluation of implant-...

Not applicable. This study was conducted without external funding. All data generated and analyzed during this study are included in this article.

References : Esthetic evaluation of implant-suppor...

Jivraj S, Chee W. Treatment planning of implants in the aesthetic zone. British Dental J. 2006;201(2):77–89. Buser D, Martin W, Belser UC. Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants. 2004;19:43–61. Huynh-Ba G, Meister DJ, Hoders AB, Mealey BL, Mills MP, Oates TW, Cochran DL, Prihoda TJ, McMahan C...

References : Esthetic evaluation of implant-suppor...

Hof M, Umar N, Budas N, Seemann R, Pommer B, Zechner W. Evaluation of implant esthetics using eight objective indices-comparative analysis of reliability and validity. Clin Oral Implants Res. 2018;29(7):697–706. Li X, Wu B, Cheng X, Li Y, Xie X, Deng F. Esthetic evaluation of implant-supported single crowns: the implant restoration esthetic index and patient perception. J Prosthodont. 2017. htt...

References : Esthetic evaluation of implant-suppor...

Rokn A, Bassir S, Ghahroudi AR, Kharazifard M, Manesheof R. Long-term stability of soft tissue esthetic outcomes following conventional single implant treatment in the anterior maxilla: 10-12 year results. Open Dent. 2016;10:602. Angkaew C, Serichetaphongse P, Krisdapong S, Dart MM, Pimkhaokham A. Oral health-related quality of life and esthetic outcome in single anterior maxillary implants. Clin...

Abbreviations : Esthetic evaluation of implant-sup...

Pink esthetic score Standard deviation Statistical Package for the Social Sciences Visual analogue scale White esthetic score

Conclusions : Esthetic evaluation of implant-suppo...

Professionally reported esthetic outcomes (PES and WES results) may not significantly correlate with patient-reported outcomes, although they are helpful in monitorization of implants in the anterior zone during follow-ups. This study reveals that smile line is a significant factor in patient satisfaction, which should be evaluated thoroughly prior to implant placement in the anterior maxilla.

Discussion : Esthetic evaluation of implant-suppor...

Only a limited number of studies compared esthetic outcomes of implants placed using different protocols [3, 25, 26]. A majority of these studies compared the results of immediate implant placement (type 1) with other protocols. Huynh-Ba et al. found no difference in terms of esthetics between type 1 and type 2 implant placement [25]. Similarly, Boardman et al. observed higher PES results followin...

Discussion : Esthetic evaluation of implant-suppor...

In the present study, only two implants in patients with thin gingival biotypes failed to reach the clinically acceptable PES level. All other patients with both thick and thin biotypes achieved either acceptable or almost perfect scores for both PES and WES. According to the results of Angkaew et al., the PES/WES scores of patients with thick gingival biotype were significantly higher than those ...

Discussion : Esthetic evaluation of implant-suppor...

Ever since the introduction of dental implants in the 1960s, they have been used worldwide with high success rates and accepted predictability [13]. Initial efforts of implant treatment mainly focused on osseointegration and function, whereas today, esthetics is also regarded as an essential component, which is commonly addressed together with functional goals of rehabilitation with dental implant...

Results : Esthetic evaluation of implant-supported...

All implants were loaded 3–6 months after implant surgery (conventional loading protocol); therefore, this parameter was not analyzed in this study. The overall effect of gingival biotype and smile line on PES, WES, or VAS was studied using a general linear regression analysis for multivariate tests. Although both PES and WES were not affected (p = 0.580, p = 303; respectively), VAS wa...

Results : Esthetic evaluation of implant-supported...

Question4. “How do you feel about the color of the gum that is around your new implant tooth?” Mean patient rating was calculated as 8.4 (range 2–10, SD ± 2.0). Median score was 9. Fifteen patients responded with a score of ≥ 8 and 17 patients responded with a score of ≥ 6. Question5. “What is your overall satisfaction with the new implant tooth?” Mean patient rating was ca...

Results : Esthetic evaluation of implant-supported...

A total of 19 (7 female and 12 male) patients, who were rehabilitated with a single implant in the anterior maxilla, were included in this study. Patients’ ages ranged between 19 and 42 with a mean of 31.8 years. None of the implants were associated with increased probing depth, bleeding, suppuration, foreign body sensation, pain, morbidity, or infection. Clinical features related to anterior s...

Methods : Esthetic evaluation of implant-supported...

All patients were assessed according to the White Esthetic Score [8] which comprised the evaluation of five variables including general tooth form, tooth contour, tooth color (hue and value), surface texture, and translucence. Each variable was given a score of 0, 1, or 2. A score of 0 indicated the worst and a score of 2 indicated the best result for each variable. The implant-supported tooth was...

Methods : Esthetic evaluation of implant-supported...

This study was conducted in accordance with the Declaration of Helsinki on medical protocol and was approved by the Akdeniz University Ethical Review Board. The patients rehabilitated with a single implant-supported fixed prosthesis in the maxillary esthetic zone at the departments of Oral and Maxillofacial Surgery and Prosthetic Dentistry of Akdeniz University between June 2015 and April 2017 we...

Background : Esthetic evaluation of implant-suppor...

Patient satisfaction, which indicates the success of the implant treatment from the patient’s perspective, is another important outcome measure and is commonly performed with questionnaires or a visual analog scale (VAS) [2, 8]. A current review of the literature, however, reveals only a limited number of studies reporting on patient-centered outcomes in addition to objective evaluations of impl...

Background : Esthetic evaluation of implant-suppor...

Rehabilitation of missing teeth in the anterior maxilla with an implant-supported fixed prosthesis is a widely accepted treatment modality [1]. Dental implants have high rates of predictability in terms of osseointegration, particularly due to improvements in treatment techniques and surface topography [2]. However, rehabilitation with dental implants is not yet considered a perfect treatment moda...

Abstract : Esthetic evaluation of implant-supporte...

This study investigated objective and patient-reported esthetic outcomes and their correlation for single-tooth implant restorations in the maxillary anterior region. Nineteen patients were included. Gingival biotypes and smile lines were evaluated. Esthetic evaluation was performed according to the pink and white esthetic scores (PES and WES). Patients rated their satisfaction regarding the impl...

Fig. 1. The clinical images of patient 4, with imp...

Fig. 1. The clinical images of patient 4, with implant-supported single crowns in regions 26 and 27. No signs of a peri-implant infection, mucositis, peri-implantitis, or marginal bone loss were detected. a Occlusal view. b Left-side view. c Orthopantogram. d Close-up radiographic view Fig. 1. The clinical images of patient 4, with implant-supported single crowns in regions 26 and 27. No sign...

About this article : Short implants in the posteri...

Lorenz, J., Blume, M., Korzinskas, T. et al. Short implants in the posterior maxilla to avoid sinus augmentation procedure: 5-year results from a retrospective cohort study. Int J Implant Dent 5, 3 (2019). https://doi.org/10.1186/s40729-018-0155-1 Download citation Received: 19 September 2018 Accepted: 20 December 2018 Published: 22 January 2019 DOI: https://doi.org/10.11...

Rights and permissions : Short implants in the pos...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Short implants in the poster...

The study was approved by the ethics commission of the medical department of Goethe University in Frankfurt am Main, Germany (79/18). All participating patients gave informed written consent to participate in the retrospective study and for publication of the obtained data. All participating patients gave informed written consent to participate in the retrospective study and for publication of th...

Author information : Short implants in the posteri...

Correspondence to Jonas Lorenz.

Author information : Short implants in the posteri...

FORM-Lab, Department for Oral, Cranio-Maxillofacial, and Facial Plastic Surgery, Medical Center of the Goethe University Frankfurt, Frankfurt am Main, Germany Jonas Lorenz, Shahram Ghanaati & Robert A. Sader Private Dental Practice, Mainz, Germany Maximilian Blume Private Practice, Bokštų 9, LT-92125, Klaipeda, Lithuania Tadas Korzinskas You can also search for this author in ...

Acknowledgements : Short implants in the posterior...

Not applicable This study was supported by a grant from the Camlog Foundation. The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.

References : Short implants in the posterior maxil...

Lorenz J, Lerner H, Sader R, Ghanaati S. Investigation of peri-implant tissue conditions and peri-implant tissue stability in implants placed with simultaneous augmentation procedure: a 3-year retrospective follow-up analysis of a newly developed bone level implant system. Int J of Impl Dent. 2017;5(1):41. Del Fabbro M, Rosano G, Taschieri S. Implant survival rates after maxillary sinus augmentat...

References : Short implants in the posterior maxil...

Lorenz J, Barbeck M, Kirkpatrick CJ, Sader R, Lerner H, Ghanaati S. Injectable bone substitute material on the basis of β-TCP and hyaluronan achieves complete bone regeneration while undergoing nearly complete degradation. Int J Oral Maxillofac Implants. 2018;33(3):636–44. Lorenz J, Kubesch A, Korzinskas T, Barbeck M, Landes C, Sader R, Kirkpatrick CJ, Ghanaati S. TRAP-positive multinucleated ...

Abbreviations : Short implants in the posterior ma...

Absent Present Bleeding on probing Disto-buccal Disto-oral Female Fixed prosthetics Male Mesio-buccal Marginal bone loss Mesio-oral Probing pocket depth Removable prosthetics

Conclusion : Short implants in the posterior maxil...

The present retrospective study analyzed the clinical and radiological performance of dental implants of 7-mm length in the posterior maxilla used to avoid sinus augmentation procedures. After a mean period of loading of 5 years, a survival rate of 100% and an absence of peri-implant infections were detected, which leads to the conclusion that “short implants” are a reliable treatment option...

Discussion : Short implants in the posterior maxil...

In a systematic review, Lemos et al. compared short implants with a length of 8 mm or less to standard implants (larger than 8 mm) placed in posterior regions of the maxilla and mandible. The authors reviewed 13 studies with a total of 1269 patients who had received a total of 2631 dental implants. Short implants showed marginal bone loss, prosthetic failures, and complication rates similar to...

Discussion : Short implants in the posterior maxil...

In the present retrospective study, dental implants of reduced length (7 mm) that were placed in the posterior maxilla to avoid sinus augmentation procedure were clinically and radiologically followed up after a mean loading period of 5 years. The clinical and radiological results demonstrate successful midterm results regarding implant survival and peri-implant hard and soft tissue health. Lo...

Results : Short implants in the posterior maxilla ...

To analyze peri-implant bone loss over the study period of 5 years, digitally recorded perpendicular single-tooth images recorded immediately after implant placement and at the follow-up investigation were compared. A mean total peri-implant marginal bone loss of 0.5 mm, ranging from 0 to 1.5 mm, was shown. Sub-analysis indicated mesial peri-implant bone loss of 0.4 mm and distal peri-impl...

Results : Short implants in the posterior maxilla ...

After patient screening was performed, 30 implants in the premolar and molar regions of the upper jaw in 14 patients met the inclusion criteria and were clinically and radiologically followed up according to the study protocol. The aim of the follow-up investigation was to analyze whether implants of 7-mm length are suitable for prosthetic rehabilitation in the atrophic maxilla to avoid a sinus au...

Materials and methods : Short implants in the post...

Implant being in situ and suitable for prosthetic rehabilitation Buccal width and thickness of peri-implant keratinized gingiva Probing depth (at 4 sites per implant) BoP (per implant) Peri-implant bone loss Presence of peri-implant osteolysis

Materials and methods : Short implants in the post...

After a mean loading period of 5 years (range 2–7 years), the implants were clinically and radiologically analyzed to determine the overall implant success, mean survival and suitability for prosthetic rehabilitation, peri-implant hard and soft tissue health, and patient acceptance. Furthermore, peri-implant hard and soft tissue indices, such as bleeding on probing (BoP), probing pocket dept...

Materials and methods : Short implants in the post...

In the present retrospective study, 14 patients (5 females and 9 males) with a mean age of 63 years (34–80 years) received Conelog® Screw-line implants (Camlog Biotechnologies, Basle, Suisse) with a length of 7 mm. In total, 30 implants were clinically and radiologically investigated after a mean loading period of 5 years (range 2–7 years). All patients from the Department for Oral...

Introduction : Short implants in the posterior max...

In the present retrospective study, implants of 7-mm length and a specific implant design, including a conical implant-abutment connection and platform switching, placed in the posterior maxilla were investigated by means of a clinical and radiological analysis after a mean loading period of 5 years. The aim of this study was to analyze whether a reduced implant length has any impact on implant s...

Introduction : Short implants in the posterior max...

In the past few decades, technical developments of dental implants in combination with continuous development of surgical techniques and biomaterials have led to an expansion of the indications for implant-retained prosthetics. Prevention of atrophy after tooth extraction by socket or ridge preservation or reconstruction of the alveolar crest in cases of atrophy by augmentation with autologous bon...

Abstract : Short implants in the posterior maxilla...

Short implants present a promising approach for patients with advanced atrophy to avoid augmentative procedures. However, concerns about increased biological and technical complications due to an unfavorable implant-crown ratio are still present. The aim of the present retrospective study was to evaluate whether a reduced implant length has any impact on implant success and peri-implant hard and ...

Fig. 4. Statistical analysis for different variabl...

Fig. 4. Statistical analysis for different variables. a Weighted mean survival rate. b Implant survival rate according to degree of penetration. c Analysis of clinical complications. d Analysis of radiographic complications Fig. 4. Statistical analysis for different variables. a Weighted mean survival rate. b Implant survival rate according to degree of penetration. c Analysis of clinical com...

Fig. 3. Graphic representation of group 1 ≤ 4...

Fig. 3. Graphic representation of group 1 ≤ 4 mm penetration and group 2 > 4 mm penetrations Fig. 3. Graphic representation of group 1 ≤ 4 mm penetration and group 2 > 4 mm penetrations

Fig. 1. Graphic representation of implants intrudi...

Fig. 1. Graphic representation of implants intruding sinus perforating or not the Schneiderian membrane Fig. 1. Graphic representation of implants intruding sinus perforating or not the Schneiderian membrane

Fig. 2. PRISMA flowchart of the screening process ...

Fig. 2. PRISMA flowchart of the screening process Fig. 2. PRISMA flowchart of the screening process

Table 3 Articles excluded and reasons for exclusio...

Reason for exclusion Investigations Study design (case series or case report) Kim et al. (2017), Hatano et al. (2007) Different grafting techn...

Table 2 Characteristics of the included investigat...

Author (year) Study design Follow-up (months) N of patients N of implants Smokers Le...

Table 1 Clinical and radiographic complications re...

Clinical complications Radiographic complications Sinusitis Thickening of Schneiderian membrane Nasal bleeding, nasal obstruction, nasal secre...

About this article : Influence of exposing dental ...

Ragucci, G.M., Elnayef, B., Suárez-López del Amo, F. et al. Influence of exposing dental implants into the sinus cavity on survival and complications rate: a systematic review. Int J Implant Dent 5, 6 (2019). https://doi.org/10.1186/s40729-019-0157-7 Download citation Received: 09 October 2018 Accepted: 06 January 2019 Published: 05 February 2019 DOI: https://doi.org/10...

Rights and permissions : Influence of exposing den...

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were m...

Ethics declarations : Influence of exposing dental...

Not applicable Not applicable Gian Maria Ragucci, Basel Elnayef, Fernando Suárez López del Amo, Hom-Lay Wang, Federico Hernández-Alfaro, and Jordi Gargallo-Albiol declare that they have no competing interests. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Author information : Influence of exposing dental ...

Correspondence to Basel Elnayef.

Author information : Influence of exposing dental ...

Department of Oral and Maxillofacial Surgery, International University of Catalonia, C/Josep Trueta Sn, Sant Cugat del Vallés, C.P 08195, Barcelona, Spain Gian Maria Ragucci, Basel Elnayef, Federico Hernández-Alfaro & Jordi Gargallo-Albiol Department of Periodontics, University of Oklahoma Health Sciences Center – College of Dentistry, Oklahoma City, OK, USA Fernando Suárez-López del ...

Acknowledgements : Influence of exposing dental im...

The authors want to thank Mr Juan Luis Gómez Martínez for the support in the statistical analysis. Not applicable Not applicable The authors do not have any financial interests, either directly or indirectly, in the products or information listed in the paper.

References : Influence of exposing dental implants...

Schwarz L, Schiebel V, Hof M, Ulm C, Watzek G, Pommer B. Risk factors of membrane perforation and postoperative complications in sinus floor elevation surgery: review of 407 augmentation procedures. J Oral Maxillofac Surg. 2015;73:1275–82. Jung JA, Choi BH, Zhu SJ, Lee SH, Huh JY, You TM, Lee HJ, Li J. The effects of exposing dental implants to the maxillary sinus cavity on sinus complications....

References : Influence of exposing dental implants...

Ardekian L, Oved-Peleg E, Mactei EE, Peled M. The clinical significance of sinus membrane perforation during augmentation of the maxillary sinus. J Oral Maxillofac Surg. 2006 Feb;64(2):277–82. Anavi Y, Allon DM, Avishai G, Calderon S. Complications of maxillary sinus augmentations in a selective series of patients. Oral Surg Oral Med Oral Patho Oral RadiolEndod. 2008;106(1):34–8. Van den Ber...

References : Influence of exposing dental implants...

Curi MM, Cardoso CL, de Ribeiro C. Retrospective study of pterygoid implants in the atrophic posterior maxilla: implant and prosthesis survival rates up to 3 years. Int J Oral Maxillofac Implants. 2015;30(2):378–83. Boyne PJ, James RA. Grafting of the maxillary sinus floor with autogenous marrow and bone. J Oral Surg. 1980;38(8):613–6. Tatum H.Jr. Maxillary and sinus implant reconstructions....

References : Influence of exposing dental implants...

Roccuzzo M, Bonino L, Dalmasso P, Aglietta M. Long-term results of a three arms prospective cohort study on implants in periodontally compromised patients: 10-year data around sandblasted and acid-etched (SLA) surface. Clin Oral Implants Res. 2014;25(10):1105–12. Esposito M, Grusovin MG, Rees J, Karasoulos D, Felice P, Alissa R, Worthington H, Coulthard P. Effectiveness of sinus lift procedures...

Conclusions : Influence of exposing dental implant...

The current review showed that the exposure of dental implants in the sinus cavity without the augmentation procedure or graft materials shows a high survival rate of 95.6%, without statistically significant differences according to the level of penetration (lower or higher to 4 mm). Changes in maxillary sinuses in relation to protruding implants within the sinus cavity do not statically affect ...

Discussion : Influence of exposing dental implants...

Consequently, it seems that maxillary sinus changes in relation to protruded implants inside the sinus cavity and does not statically affect to implant survival rate neither to clinical nor radiographic complications. Several limitations could be described for the present review. Firstly, there is a lack of a control group in the included studies, to compare outcomes and complications, with impla...

Discussion : Influence of exposing dental implants...

Pneumatization of the maxillary sinus and resorption of the residual alveolar ridge following tooth extraction can compromise the dental implant placement. Similarly, extension of the dental implants inside the maxillary sinus cavity is not rare. Some studies have observed some differences in relation to the depth of the implant extension inside the sinus cavity. When the implants penetrate inside...

Results : Influence of exposing dental implants in...

Seven studies [27,28,29,30,31,32,33] provide information on clinical complications with a global sample of 232 patients. Clinical complications among the different authors range from 0 to 14.3%, being the weighted mean complication rate 3.4% with an IC 95% [0 7.5] (Fig. 4c) Clinical complications analyzed in the studies were sinusitis, nasal bleeding, nasal obstruction, nasal secretion, mucopurul...

Results : Influence of exposing dental implants in...

An initial screening yielded a total of 3551 publications of which 26 potentially relevant articles were selected after an evaluation of their titles and abstracts. Full text of these articles was obtained and evaluated thoroughly. Of these, eight articles [26,27,28,29,30,31,32,33] (Table 2) fulfilled the inclusion criteria and subsequently were included in the qualitative analysis (Fig. 2). Rea...

Materials and methods : Influence of exposing dent...

Heterogeneity was assessed based on calculation of the I2 statistic (percentage variability of estimated effect that can be attributed to the heterogeneity of the effects) and the null statistic test. Galbraith graphs displayed the degree of heterogeneity. In studies where great heterogeneity was detected, a sensitivity analysis was performed to determine its source. Funnel plots and the Egger tes...

Materials and methods : Influence of exposing dent...

Articles were included in this systematic review if they met the following inclusion criteria: human prospective or retrospective studies, reporting outcomes of implant placed perforating the sinus floor with implant burs, and without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material. The intrusion into the sinus cavity can occur during drilling or implant p...

Materials and methods : Influence of exposing dent...

This systematic review and subsequent meta-analysis follow the guidelines of the PRISMA statement. The following focus question was developed: Is the intrusion of dental implants into the sinus cavity during implant drilling or implant placement, without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material, has an effect on implant survival or increase clinica...

Introduction : Influence of exposing dental implan...

Intrusion of dental implants into the maxillary sinus perforating through the Schneiderian membrane is considered a cause of undesirable complications [24, 25]. However, this phenomenon has never been properly evaluated and systematically studied. For this reason, the aim of this systematic review was to assess the implant survival and complication rates of implants intruding into the sinus cavity...

Introduction : Influence of exposing dental implan...

The edentulous posterior maxillary region often presents with unique challenging conditions in implant dentistry [1]. Limited bone height secondary to pneumatization of the maxillary sinus and the resorption of the alveolar ridge preclude in many instances the installation of dental implants. To compensate for the lack of bone height, several treatment options have been proposed. The most conserv...

Abstract : Influence of exposing dental implants i...

The overall survival rate of the implants into the sinus cavity was 95.6%, without statistical differences according to the level of penetration. The clinical and radiological complications were 3.4% and 14.8% respectively. The most frequent clinical complication was the epistaxis, and the radiological complication was thickening of the Schneiderian membrane, without reaching statistical significa...

Abstract : Influence of exposing dental implants i...

After tooth loss, the posterior maxilla is usually characterized by limited bone height secondary to pneumatization of the maxillary sinus and/or collapse of the alveolar ridge that preclude in many instances the installation of dental implants. In order to compensate for the lack of bone height, several treatment options have been proposed. These treatment alternatives aimed at the installation o...

Table 7 Cox regression analyses for cumulative sur...

  Hazard ratio 95% confidence interval p value Gender (male) 1.82 0.946~3.487 ...

Table 6 Cox regression analyses for cumulative inc...

  Hazard ratio 95% confidence interval p value Gender (male) 2.38 1.138~5.362 ...

Table 5 Cox regression analyses for implant surviv...

  Hazard ratio 95% confidence interval p value Gender (male) 1.99 0.538~8.201 ...

Table 4 Distribution of implants by length and loc...

Dia. (mm) Maxilla anterior Maxilla posterior Mandible anterior Mandible posterior Tot...

Table 3 Distribution of implants by diameter and l...

Dia. (mm) Maxilla anterior Maxilla posterior Mandible anterior Mandible posterior Tot...

Table 2 Distribution of implants in situ (n = 22...

Position 1 2 3 4 5 6 ...

Table 1 Age and gender distributions (n = 92)

Age/gender Male Female Total 20–29 3 ...

References: Retrospective cohort study of rough-su...

References Brånemark PI, Adell R, Breine U, Hansson BO, Lindström J, Ohlsson A. Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg. 1969;3:81–100. Buser D, Sennerby L, De Bruyn H. Modern implant dentistry based on osseointegration: 50 years of progress, current trends and open questions. Periodontol. 2017;73:7–...

Conclusions: Retrospective cohort study of rough-s...

Conclusions In conclusion, our analyses revealed a cumulative survival rate of 89.8% of TPS-surface implants with at least 25 years of functioning. The survival rate of maxillary positioned implants was significantly lower than that of mandibulary positioned implants. The patient gender, implant location, and width of keratinized mucosa affected the rate of peri-implantitis, resulting in l...

Results: Retrospective cohort study of rough-surfa...

A total of 48 implants were eventually accompanied by a peri-implant infection: the cumulative incidence of peri-implantitis was 9.5, 15.3, 21.0, and 27.9% at 5, 10, 15, and 25 years after the prosthesis delivery, respectively (Fig. 3). After stepwise backward selection, the gender, implant type, and width of keratinized mucosa showed the significant difference in the cumulative survival rate (T...

Results: Retrospective cohort study of rough-surfa...

Results Patient cohort A total of 92 patients (38 men, 54 women; mean age 54.3 years, range 20–78) received implant-supported prostheses (at the seven private practices) between 1984 and 1990. The distribution of patients by age and gender is presented in Table 1. Fifty-seven patients (140 implants) were considered dropouts due to the fact that no data were obtained at the endpoint, bu...

Methods: Retrospective cohort study of rough-surfa...

Methods Study design This retrospective observational study was approved by the ethical committee of Nagasaki University (No. 1512). The cases of all of the patients who underwent dental implant treatment with a TPS-surfaced solid-screw implant and whose prosthesis was set in the years 1984–1990 at seven private practices were analyzed. All inserted implants were either a TPS-type (TPS-t...

Background: Retrospective cohort study of rough-su...

Background Dental implant treatment based on the concept of osseointegration [1] is now a widely accepted restorative treatment for fully and partially edentulous patients. In the earliest days of the use of osseointegrated implants, two different topographies were applied on the implant surfaces: a machined minimally rough titanium surface such as the Brånemark system and a rough micropor...

Retrospective cohort study of rough-surface titani...

Abstract Background The longitudinal clinical outcomes over decades contribute to know potential factors leading to implant failure or complications and help in the decision of treatment alternatives. Methods The cases of all patients who received dental implants treated with titanium plasma-sprayed surfaces and whose prostheses were set in the period 1984–1990 at seven...

Figure 4. Patient satisfaction throughout the stud...

  Figure 4. Patient satisfaction throughout the study

Figure 3. Bone level changes from loading to 5-yea...

  Figure 3. Bone level changes from loading to 5-year follow up

Figure 2. Clinical parameters and soft tissue para...

  Figure 2. Clinical parameters and soft tissue parameters. a Modified plaque index. Error bars indicate standard deviation. * = p ≤ 0.05, *** = p ≤ 0.001. b Sulcus bleeding index. Error bars indicate standard deviation. * = p ≤ 0.05, *** = p ≤ 0.001. c Pocket probing depth. The asterisk represents statistically significant differences (* = p ≤ 0.05) observed between ...

Figure 1. Study flow diagram

Figure 1. Study flow diagram: follow up status and reasons for not completing the study; six-month, 2-year and 4-year follow up was optional Figure 1. Study flow diagram: follow up status and reasons for not completing the study; six-month, 2-year and 4-year follow up was optional

Table 4 Life table analysis showing the cumulative...

Table 4 Life table analysis showing the cumulative success rate according to Albrektsson et al. and Buser et al.   Interval(months) Implants in interval According to Albrektsson et al. According to Buser et al. Implants withdrawn during interval Failures during interval Cumulative success rate (%) Implants withdrawn during interval Failures during interval Cumulativ...

Table 3 Patient demographics with respect to impla...

Table 3 Patient demographics with respect to implants     Overall Subgroup* Platform switching Platform matching Total Implants, n 285 203* 68* Number of implants placed per patient, n (%) 1 125 (63.8) 97 (67.4) 20 (48.8) 2 56 (28.6) 37 (25.7) 16 (39.0) 3 12 (6.1) 7 (4.9) 5 (12.2) 4 3 (1.5) 3 (2.1) 0 (0.0) Implant...

Table 2 Patient demographics

Table 2 Patient demographics   Overall Subgroup* Platform switching Platform matching Patients, n (%) 196 (100) 144 41 Sex, n (%)  Male 87 (44.4) 62 (43.1) 19 (46.3)  Female 109 (55.6) 82 (56.9) 22 (53.7) Age, years  Mean (SD) 51.5 (14.2) 53.1 (14.4) 47.4 (12.9)   Range 17.9–82.1 17.9–82.1 19.3–78.5 Pr...

Table 1 Table of study centers

Investigator* City/country Number of patients included Number of implants included Dr. Helfried Hulla Strass in Steiermark, Austria 10 15 Prof. DDr. Gerald Krennmair Marchtrenk, Austria 10 20 Dr. S. Marcus Beschnidt (PI) Baden-Baden, Germany 8 12 Dr. Karl-Ludwig Ackermann Filderstadt, Germany 14 18 Dr. Thomas Barth Leipzig, Germany 15 28 Dr...

Abbreviations & References: Implant success and su...

Abbreviations ASA: American Society of Anesthesiologists MPI: Modified Plaque Index PPD: Pocket probing depth RCT: Randomized controlled clinical trial SBI: Sulcus Bleeding Index SD: Standard deviation SLA: Sand-blasted, large grit, acid-etched References Hjalmarsson L, Gheisarifar M, Jemt T. A systematic review of survival of s...

Discussion and conclusions: Implant success and su...

The appearance of poorer oral hygiene later in the study also appears to correspond with the drop in follow-up attendance, which again supports the importance of follow-up. All other complications could be resolved and were not persisting. Furthermore, patients selected for inclusion in this study were optimal candidates for dental implants. Though the inclusion criteria predestinate the patient s...

Discussion and conclusions: Implant success and su...

At 5-year follow-up, the overall SBI was 0.32 ± 0.49, reflective of no bleeding given that 0 equals no bleeding and 1 equals isolated bleeding spots visible [27]. The PPD initially decreased within the first 6 months from which point it significantly increased to 2.34 ± 1.18 mm at 5-year follow-up. Nevertheless, the measured mean PPD still reflects the norm for conventionally placed i...

Discussion and conclusions: Implant success and su...

On the one hand, the variety of bone level changes in this study may be explained by different vertical soft tissue thicknesses, but cannot be validated due to these missing data. On the other hand, there are multiple confounding factors influencing the change in bone level, such as the size of the platform (mismatch), occlusal loading, and the microgap. Additional to the standard success criteria...

Discussion and conclusions: Implant success and su...

Over the 5-year study period, we report

Discussion and conclusions: Implant success and su...

At 3-year follow-up, bone loss was noted in one patient (reclassified as peri-implantitis at the 4-year follow-up) and an important bone loss (due to poor oral hygiene and bruxism; two implants) in a patient with psychosocial issues who could not be treated during the study. Such a patient would not have been included in an RCT. Consequently, three implants were lost based on the bone loss criter...

Discussion and conclusions: Implant success and su...

Discussion and conclusions This large, multicenter study provides real-life long-term data on 285 implants placed in 196 patients. The results show that the placement of CAMLOG SCREW-LINE implants with platform-matching or platform-switching abutments results in high survival and success in the long term. The overall success rate for implants was 97.1% at 5-year post-loading, and 97.4% and 96.2...

Results: Implant success and survival rates (3)

Jemt papilla score At loading, the Jemt papilla score was 1.93 ± 1.01, significantly increasing to 2.14 ± 0.95 at 5-year follow-up (p = 0.023) (Fig. 2d). For the platform-switching subgroup, a significant difference was observed between baseline and 5-year follow-up (p 

Results: Implant success and survival rates (2)

Implant survival The cumulative survival rate was 100% at 1-year follow-up, 99.6% at 3-year follow-up, and 98.6% at 5-year follow-up. All three late failures were in the platform-switching subgroup. Clinical parameters/soft tissue parameters Plaque index Mean modified plaque indices were very low at below 0.5 for all but one measurement throughout the course of the study (Fig. 2a). At loading...

Results: Implant success and survival rates (1)

Results Patient demographics  In total, 196 patients from 17 centers met the inclusion criteria for this study and were included in the per-protocol analysis. In total, 285 implants were placed (Table 1). At the 5-year follow-up, data were available for the 137 patients who completed the study (Fig. 1). Patient demographic data is presented in Tables 2 and 3. Implant success Implant success...

Methods: Implant success and survival rates (4)

The primary stability of the implant was assessed during surgery. Implant success and survival were evaluated in the group of implants restored with abutments [5, 29] at both placements of the provisional and definitive prostheses and at each follow-up visit thereafter. Implants were deemed successful in accordance with the criteria for implant success laid down by Albrektsson et al. [30]. Implan...

Methods: Implant success and survival rates (3)

  Assessments Throughout the study, only radiographs consistent with standard implant procedures were taken. Bone level changes were assessed based on available and evaluable standardized periapical radiographs with a film-holder using parallel-technique or panoramic radiographs (depending on the standard in the study centers). Baseline was defined as the time of the first prosthetic installati...

Methods: Implant success and survival rates (2)

The treatment indications were single or multiple tooth replacement in the maxilla or mandible without the use of simultaneous augmentation or membrane, of which the implants were to be restored with either fixed single crown or fixed partial denture restorations. Treatment procedure Patients were to be treated according to standard practice for implant procedures applicable in the countries par...

Methods: Implant success and survival rates (1)

Methods Study design This was a prospective multicenter non- interventional study to assess implant success and survival rates in daily dental practices using the CAMLOG SCREW-LINE implants (CAMLOG Biotechnologies AG, Basel, Switzerland) used with or without platform-switching abutments. Patients were enrolled over a period of 2 years from October 2008 to September 2010 from 17 sites across f...

Background: Implant success and survival rates (2)

In the present study, CAMLOG SCREW-LINE implants with the Promote plus surface (sandblasted and acid-etched surface) were used. These implants in combination with platform-matching abutments have been shown to have high long-term success rates ranging from 97.8 to 100% at 5-year to 10-year follow-up [9,10,11,12,13]. They can be restored with either platform-matching or platform-switching abutments...

Background: Implant success and survival rates (1)

Background   Success and survival rates of endosseous implants are well-documented in a number of controlled clinical trials and systematic reviews [1,2,3]. Generally, controlled trials evaluate endosseous implants in specific clinical situations; thus, the patient population is subjected to rigorous inclusion criteria and follow-up. Accordingly, controlled clinical trials do not reflect th...

Implant success and survival rates in daily dental...

Implant success and survival rates in daily dental practice: 5-year results of a non-interventional study using CAMLOG SCREW-LINE implants with or without platform-switching abutments Abstract Background The performance of dental implants in controlled clinical studies is often investigated in homogenous populations. Observational studies are necessary to evaluate the outcome of implant resto...

Figure 7. Post-operative occlusal photograph of th...

Figure 7. Post-operative occlusal photograph of the maxilla

Figure 6. Post-operative lateral view of the right...

  Figure 6. Post-operative lateral view of the right maxillary arch

Figure 5. Post-operative lateral view of the left ...

  Figure 5. Post-operative lateral view of the left maxillary arch

Figure 4. Post-operative frontal view with teeth i...

  Figure 4. Post-operative frontal view with teeth in occlusion

Table 2 Chronological timeline of the implant ther...

Date Site number Implant diameter (mm) Implant length (mm) Immediate load Bone graft augmentation 3/26/14 12 4.3 10 Yes Allograft 3/26/14 14 4.3 10 Yes None 11/10/14 10 3.5 13 Yes Allograft 3/5/15 7 3.5 13 Yes Allograft 4/19/16 11 4.3 11.5 Yes None 2/22/17 3 4.3 10 Yes Allograft 2/22/17 4 5.0 10 Yes Allograft ...

Figure 1. Characteristic blue sclerae

  Figure 1. Characteristic blue sclerae

Table 1 Osteogenesis imperfecta classifications

Table 1 Osteogenesis imperfecta classifications Type Inheritance Gene Locus Clinical features OMIM I AD COL1A1 or COL1A2 17q21.33 or 7q21.3 Variable bone fragility, moderate bone deformity, blue sclerae, possible dentinogenesis imperfecta 166,200 II AD COL1A1 or COL1A2 17q21.33 or 7q21.3 Perinatally lethal 166,210 III AD COL1A1 or COL1A2 17q21....

References : Implant therapy for a patient

References Sillence DO, Senn A, Danks DM. Genetic heterogeneity in osteogenesis imperfecta. J Med Genet. 1979;16:101–16. Orioli IM, Castilla EE, Barbosa-Neto JG. The birth prevalence rates for the skeletal dysplasias. J Med Genet. 1986;23:328–32. Stevenson DA, Carey JC, Byrne JL, Srisukhumbowornchai S, Feldkamp ML. Analysis of skeletal dysplasias in the Utah population. Am J Med Genet...

Discussion : Implant therapy for a patient (2)

Discussion The vast majority of published articles regarding OI type I revolve around fractures of the long bones and treatment strategies. An extensive literature search for manuscripts detailing the implant therapy for patients diagnosed with OI produced a marginal amount of literature (Table 3). Our case posits that oral restoration is attainable without implant failure for OI type I patien...

Case presentation : Implant therapy for a patient ...

  Surgical technique The patient underwent implant therapy in stages under general anesthesia with immediate load protocol. Intravenous access was obtained, and the patient was anesthetized under general anesthesia by our anesthesiologist. Carpules of 2% lidocaine with 1:100,000 epinephrine, 4% articaine hydrochloride with 1:100,000 epinephrine (Septocaine), and 0.5% bupivacaine hydrochloride w...

Case presentation : Implant therapy for a patient ...

Case presentation Evaluation A 53-year-old male diagnosed with OI type I was referred to our clinic for extraction of the remaining maxillary teeth and evaluation for full arch immediate load hybrid prosthesis. His clinical history included osteogenesis type 1, bipolar disorder, alopecia, and hypothyroidism. The patient presented with normal stature, measuring 170.18 cm and weighing 81.65 kg...

Introduction : Implant therapy for a patient

Introduction Osteogenesis imperfecta (OI), colloquially known as “brittle bone disease,” is a broad term for a group of congenital disorders affecting the connective tissue resulting in a susceptibility to fractures. In 1979, Sillence et al. conducted an epidemiological and genetic study of OI patients [1]. These patients were grouped according to four distinct syndromes: (1) dominantly inh...

Implant therapy for a patient with osteogenesis im...

Implant therapy for a patient with osteogenesis imperfecta type I: review of literature with a case report Abstract Bone fragility and skeletal irregularities are the characteristic features of osteogenesis imperfecta (OI). Many patients with OI have weakened maxillary and mandibular bone, leading to poor oral hygiene and subsequent loss of teeth. Improvements in implant therapy have allowed f...

Table 1 Comparison of OHIP-14

Table 1 Comparison of OHIP-14 and its domains in the pre-and postoperative periods OHIP-14 Preoperative Postoperative P value Median (min-max) D1 6 (2–8) 0 (0–3) 0.002 D2 5 (1–8) 0 (0–3) 0.002 D3 7.5 (1–8) 0 (0–4) 0.002 D4 7.5 (2–8) 0 (0–1) 0.002 D5 8 (3–8) 0 (0–4) 0.002 D6 2 (0–8) 0 (0–0) 0.003 D7 4 ...

Figure 8. Final aspect

  Figure 8. Final aspect

Figure 7. Panoramic radiography of the follow-up

  Figure 7. Panoramic radiography of the follow-up

Figure 6. Tomographic scan of the follow-up

  Figure 6. Tomographic scan of the follow-up

Figure 5. Mini-pillar guide

Figure 5. a Mini-pillar guide. b Installation of the mini-pillars. c Protectors on the mini-pillars. d Relief of the prosthesis on the mini-pillars

Figure 4. Insertion of the implant

  Figure 4. Insertion of the implant. a Prototyped surgical guide installed and stabilized. b Long transmaxillary implants are placed on both sides of the maxilla. c Long transmaxillary implant placement with the final insertion using a ratchet or tufted wrench

Figure 3. Surgical guide

  Figure 3. Surgical guide. a Surgical guide in occlusal view. b Surgical guide in frontal view. c Prototyped model of the atrophic maxilla

Figure 2. Maxillary computed tomography. a Axial ...

  Figure 2. Maxillary computed tomography. a Axial view. b Coronal view

Figure 1. Schematic drawing of the transmaxillary ...

  Figure 1. Schematic drawing of the transmaxillary implant. Perforation is made using the 2.0 mm lance implant, for giving guidance and stability to the next drill, using the 3.0 mm implant

References: Long transmaxillary implants

References Alzarea BK. Assessment and evaluation of quality of life (OHRQoL) of patients with dental im-plants using the Oral Health Impact Profile (OHIP-14) - a clinical study. J Clin Diagn Res. 2016;10:57–60. Aparicio C, Manresa C, Francisco K, Ouazzani W, Claros P, Potau JM, Aparicio A. The long-term use of zygomatic implants: a 10-year clinical and radiographic report. Clin Implant D...

Discussion: Long transmaxillary implants

Discussion Considering the particularities of rehabilitation treatments with implants, such as patients with the atrophic edentulous maxilla, and particularly rehabilitation using long implants, this study aimed to assess the impact of using a modified long transmaxillary implant, placed horizontally on the OHRQoL of patients with the atrophic maxilla. The missing teeth impair mastication ...

Results: Long transmaxillary implants

Results The study consisted of 12 individuals, with 10 (83.3%) females and two (16.7%) males. The mean age of the sample was 55.83 ± 2.78 years. A total of 12 maxillary atrophic patients were rehabilitated, 10 using the transmaxillary implants. Of these, two patients rehabilitated with the transmaxillary implant required postoperative adjustments because the implants were lost. In the first c...

Materials and methods: Long transmaxillary implant...

  Surgical procedures External antisepsis was performed on the face using 2% Riorex chlorhexidine digluconate (Rioquímica, São José do Rio Preto, SP, Brazil) and intrabuccal (intraoral) antisepsis was performed using digluconate 0.12% chlorhexidine (Colgate, São Paulo, SP, Brazil). The entire maxilla was anesthetized using 4% articaine and 1:100,000 epinephrine (DFL, Rio de Janeiro, Brazil)...

Materials and methods: Long transmaxillary implant...

The transmaxillary implant is more conservative than the zygomatic implant, because it is installed only in the lower third of the maxilla. The zygomatic implant can reach noble regions of the face and can cause serious risks of injury to support structures, including the face, eye socket, and infratemporal fossa. Long transmaxillary implants are positioned horizontally in the maxillary bone, unli...

Materials and methods: Long transmaxillary implant...

Materials and methods Ethical aspects This retrospective case series was approved by the local Research Ethics Committee (CAAE 98088718.5.0000.0093). Patients were informed of the nature of the study and procedures, according to the Free and Informed Consent Term. Additionally, this study followed the Helsinki guidelines [19]. Study design Twelve adult patients of both sexes were evaluated. ...

Background: Long transmaxillary implants (1)

Background The introduction of osseointegrated implants is considered one of the greatest breakthroughs in dentistry [4]. Dental implants have been used in edentulous jaws to improve the retention and stability of complete dentures. Attachment to implants, in addition to improving stability and functional aspects, increases patient satisfaction [7, 8]. In addition, implant connection improves ...

Long transmaxillary implants

Long transmaxillary implants improve oral health-related quality of life of patients with atrophic jaws-a case series Abstract Background The advancement of contemporary dentistry is related to the improvement of existing techniques, materials, and technology, consistently for improving people’s oral health, which can ultimately reflect better quality of life. This study aimed to evaluate t...

Figure 2. Clinical image of patient 4

  Figure 2. Clinical image of patient 4: a region 21 before implant placement. b, c Implant placement using the GBR procedure with a synthetic bone substitute material composed of HA + β-TCP

Figure 1. Schematic representation of the technica...

    Figure 1. Schematic representation of the technical characteristics of the investigated C-Tech Esthetic Line implant system (provided by the manufacturer)

Table 2 Results from the clinical and radiological...

Patient Implant-localization (region) Implant loss (+/−) Buccal width of keratinized peri-implant gingiva (mm) Buccal thickness of keratinized peri-implant gingiva (mm) Pink Esthetic Score (PES) Probing depth (mm) at four sites (mb, db, mo, do) Bleeding on Probing (+/−) at four sites (mb, db, mo, do) Peri-implant bone loss (mm) Presence of peri-implant osteolysis (+/−) ...

Table 1 Participating patients and the number and ...

Patient Gender (m/f) Age (years) Implant localization (region) Implant diameter (mm) Implant length (mm) Augmentation material Prosthetic rehabilitation 1 f 50 32 3.5 13 HA + β-TCP r.p       34 4.3 11 HA + β-TCP r.p       42 3.5 13 HA + β-TCP r.p       44 4.3 11 HA + β-TCP r.p 2 m 61 36 3.5 11 HA + β-TCP ...

Discussion: Investigation of peri-implant in impla...

Abbreviations β-TCP: β-tricalcium phosphate BOP: Bleeding on probing F.P.: Fixed prosthetics GBR: Guided bone regeneration HA: Hydroxyapatite MNGCs: Multinucleated giant cells PES: Pink Esthetic Score R.P.: Removable prosthetics References Gurgel BC, Montenegro SC, Dantas PM, Pascoal AL, Lima KC, Calderon PD. Frequency o...

Discussion: Investigation of peri-implant in impla...

Comparing the present results to the aforementioned study with the same implant system on immediately placed implants, it seems that the GBR augmentation procedure has no influence on the long-term stability of the implants. In both studies with different placement modalities and protocols, comparable clinical and radiological results were achieved. This leads to the assumption that the inve...

Discussion: Investigation of peri-implant in impla...

The tissue reaction, however, did not only differ in bone substitute materials of different origin but also in bone substitute materials of the same origin. In an in vivo trial, two xenogeneic bone substitute materials processed with different techniques were implanted subcutaneously in CD-1 mice for up to 60 days. Both bone substitute materials showed good integration within the peri-impla...

Discussion: Investigation of peri-implant in impla...

Discussion In the present retrospective study, C-Tech bone level implants placed simultaneously with a GBR procedure around the implant shoulder were investigated clinically and radiologically after at least 3 years of loading to assess peri-implant tissue conditions and document peri-implant tissue stability. A total of 47 implants were placed in the upper (23 implants) and lower jaw (24...

Results: Investigation of peri-implant in implants

Results Altogether, 47 implants were placed in the upper and lower jaws of a total of 20 patients. In all implants, lateral augmentation in a GBR process was performed simultaneously with implant placement due to reduced horizontal or vertical height of the alveolar crest. A total of 23 implants were placed in the upper jaw and 24 implants in the lower jaw. The implant diameter varied between 3...

Methods: Investigation of peri-implant in implants...

C-Tech implant system In the present retrospective study, bone level implants (C-Tech Esthetic Line implants) were investigated clinically and radiologically. The bone level implant system has a Morse-locking conical implant-abutment connection with platform switching and an indexing hex that allows subcrestal implant placement and aims to prevent peri-implant bone loss. The surface of the implan...

Methods: Investigation of peri-implant in implants...

Methods Patient population In the present retrospective study, 47 dental implants (C-Tech Esthetic Line implants) from 20 patients (11 female, 9 male) with a mean age of 58.5 years (45–75 years) were analyzed clinically and radiologically. Implant placement and follow-up investigation was performed at the HL Dentclinic in Baden-Baden, Germany. The study was approved by the ethics commissio...

Background: Investigation of peri-implant in impla...

Regarding the stability of peri-implant hard and soft tissue, biological or anatomical factors are not the only elements that could be proven to have an impact. Technical factors such as the implant-abutment connection are also known to be key factors for long-term stable hard- and soft-tissue health [11]. Regarding the implant-abutment connection, which seems to be the key issue, located on the i...

Background: Investigation of peri-implant in impla...

However, in most patients, the local bone amount is reduced due to atrophy, inflammatory processes, or resectional defects. Therefore, in the past few years, different techniques have been described to enlarge the local bone amount in prospective implant sites [7]. Besides methods such as GBR or the sinus augmentation technique, different augmentation materials have been investigated and establish...

Background: Investigation of peri-implant in impla...

Background   The prevalence of peri-implantitis has grown in the past few years and has become a major issue in implant dentistry. Long-term stable and healthy soft- and hard-tissue conditions should be achieved in combination with esthetically and functionally satisfying results. However, the rising number of placed implants in the past decades has come with an increase in the prevalence of ...

Investigation of peri-implant in implants

Investigation of peri-implant tissue conditions and peri-implant tissue stability in implants placed with simultaneous augmentation procedure: a 3-year retrospective follow-up analysis of a newly developed bone level implant system Abstract Background Guided bone regeneration (GBR) has been proven to be a reliable therapy to regenerate missing bone in cases of atrophy of the alveolar crest. T...

Figure 3. Example of another case involved in the ...

  Figure 3. Example of another case involved in the study. a Preoperative view –premolars and molars are missing in left mandible. b Preoperative CT scan. The width of the ridge was around 4 mm. c Baseline periapical radiograph. Four narrow diameter implants were placed to restore the area. d Buccal view of the final full-contour zirconia restoration. e Periapical radiograph at 1...

Figure 2. Case 1: Example of one case involved in ...

  Figure 2. Case 1: Example of one case involved in the study. a Preoperative view of a partial edentulism in posterior mandible. b Preoperative CT scan. The width of the ridge was 4 mm. c Four narrow diameter implants were placed and left to a nonsubmerged healing. d Baseline periapical radiograph. e Buccal vieew of the final metal ceramic restoration. f Periapical radiograph at ...

Table 4 Comparison of mean bone levels (means ± S...

Diameter 2.75 mm    Follow-up Mean bone level changes (mm) (n = 69) 0–6 months (95% CI) (n = 67) 0–12 months (95% CI) (n = 67) p inter-groups  Baseline 0.02 ± 0.07 −0.18 (−0.09; −0.27) −0.47 (−0.27; −0.67) p = 0.786  6 months 0.20 ± 0.12 p intra-group  12 months 0.49 ± 0.30 p 

Table 2 Dimensions (diameter and length) and final...

Length (mm) 8 18 (14.5%) 10 56 (45.2%) 11.5 43 (34.7%) 13 7 (5.6%) Diameter (mm) 2.75 69 (55.6%) 3.25 55 (44.4%) Insertion torque (Ncm) 30 21 (16.9%) 35 16 (12.9%) 40 10 (8.1%) 45 11 (8.9%) 50 32 (25.8%) 55 7 (5.6%) 60 16 (12.9%) 65 5 (4.1%) 70 6 (4.8%)

Table 1 Features of the subjects included in the s...

Number of patients 42 Males (%) 18 (42.9%) Females (%) 24 (57.1%) Mean age at insertion (range) 62.6 (49–73) Smokers (less than 10 cigarettes/die) 12 (28.6%) Diseases in history  Controlled diabetes type 2 11 (26.2%)  Hypertension 19 (45.2%) Site of insertion  Premolar 81 (65.3%)  Molar 43 (34.7%) Opposite dentition ...

Figure 1. Characteristics of the implants used in ...

  Figure 1. Characteristics of the implants used in the study: a external macro-design of JDIcon Ultra S, 2.75 mm diameter implant and b external macro-design of JDEvolution S, 3.25 mm diameter implant

References: Narrow implants supporting a fixed spl...

References Esposito M, Grusovin MG, Maghaireh H, Worthington HV. Interventions for replacing missing teeth: different times for loading dental implants (Review). Cochrane Database Syst Rev. 2013;(3):CD003878. https://doi.org/10.1002/14651858.CD003878.pub5. Esposito M, Grusovin MG, Felice P, Karatzopoulos G, Worthington HV, Coulthard P. The efficacy of horizontal and vertical bone augmenta...

Discussion: Narrow implants supporting a fixed spl...

Klein et al., in a recent systematic review, reported that the survival rate of implants with a diameter of

Discussion: Narrow implants supporting a fixed spl...

Discussion Dental implants with a reduced diameter are commonly used where bone width is narrow or in cases of restricted mesiodistal anatomy such as laterally maxillary and mandibular incisors. They could also be a viable alternative to bone augmentation especially in challenging situations such as the posterior regions of the mandible. While it has been shown that it is possible to horizo...

Results: Narrow implants supporting a fixed splint...

Results Forty-eight patients were screened for eligibility, but six subjects were not included for the following reasons: five patients (10.4%) were hesitant to receive implant treatment, and one patient (2.1%) was treated with intravenous amino-bisphosphonates. Forty-two patients were then considered eligible and were consecutively enrolled in the study. All patients were treated according to ...

Methods : Narrow implants supporting a fixed splin...

Secondary outcome measures were as follows: Peri-implant marginal bone level changes: evaluated on intraoral radiographs taken with the paralleling technique at implant placement, 6 months and 1 year after loading. All measurements were taken by an independent assessor (LS). Radiographs were scanned, digitized in JPG format, converted to TIFF format with a 600 dpi resolution, and stored in...

Methods : Narrow implants supporting a fixed splin...

On the day of surgery, patients were treated under local anesthesia. Full-thickness crestal flaps were elevated with a minimal extension to reduce patient discomfort. The implant sites were prepared according to the procedure recommended by the implant manufacturer (JDentalCare, Modena, Italy). Tapered narrow-diameter implants titanium grade 5 (2.75 and 3.25 mm diameter, respectively, JDIcon Ult...

Methods : Narrow implants supporting a fixed splin...

Methods The present prospective study was conducted at a private practice (Tommaso Grandi, Modena) in Italy between October 2014 and January 2016. Any patient with partial edentulism in posterior regions of mandible (premolar/molar areas), requiring one multiple tooth implant-supported restoration (2-, 3-, or 4-unit bridge), having a residual bone height of at least 8 mm and a thickness of at ...

Background : Narrow implants supporting a fixed sp...

Background Historically, implants have been used and documented mainly with diameters between 3.7 and 4.3 mm. Employing these diameters for numerous indications, scientifically substantiated treatment protocols with excellent long-term results have been established [1]. One disadvantage of a standard-diameter implant is the fact that, in clinical use, the available horizontal crestal dimension...

Narrow implants supporting a fixed splinted prosth...

Narrow implants (2.75 and 3.25 mm diameter) supporting a fixed splinted prostheses in posterior regions of mandible: one-year results from a prospective cohort study   Abstract Background Can multiple splinted narrow-diameter implants be used as definitive implants in patients with insufficient bone ridge thickness in posterior regions of the mandible? With this aim, we evaluated their out...

Table 5 Multiple regression coefficients (p 

  Sleeve length Clearance Total length Offset Error at the apex − 0.1854 0.0037 0.0453   Error at the neck − 0.1041 0.0018   0.0461

Table 4 Error at the neck (mm)

Table 4 Error at the neck (mm) Sleeve length (mm) Clearance (μm) Offset (mm) 6 7 8 9 10 11 12 13 14 15 16 17 4 50 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.2 80 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.3 0.3 0.3 110 0.1 0.1 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.4 0.4 0.4 140 0.1 0.2 0.2 0.2 0.3 0.3 0.4 0.4 0.4...

Table 3 Error at the apex (mm) and deviation of im...

Table 3 Error at the apex (mm) and deviation of implant axis (degrees) for sleeve lengths 6 and 7 mm     Sleeve length (mm) Clearance (μm) Deviation (°) Total length (mm) 16 17 18 19 20 21 22 23 24 25 26 27 28 29 6 50 0.5 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 80 0.8 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.3...

Table 2 Error at the apex (mm) and deviation of im...

Table 2 Error at the apex (mm) and deviation of implant axis (°) for sleeve lengths 4 and 5 mm   Sleeve length (mm) Clearance (μm) Deviation (degrees) Total length (mm) 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 4.00 50.00 0.72 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 80.00 1.15 0.2 0.3 0.3 0.3 0.3...

Table 1 Range of various maximum permissible error...

Table 1 Range of various maximum permissible errors as calculated in the present study     Axis deviation (°) Error at the neck (mm) Error at the apex (mm) Vertical error at the apex (mm) Min 0.4 0.1 0.1 0.0 Max 5.9 1.5 2.8 0.1

Figure 2. The various errors in implant positionin...

  Figure 2. The various errors in implant positioning

Figure 1. The parameters used for the calculation ...

Figure 1. The parameters used for the calculation of the various errors and the deviation of implant axis Figure 1. The parameters used for the calculation of the various errors and the deviation of implant axis

References : CAD/CAM implant surgical guides

Abbreviations 3d: Three dimensional CAD: Computer-aided design CAM: Computer-aided manufacturing CBCT: Cone beam computed tomography CI: Confidence interval CT: Computed tomography Dicom: Digital imaging and communications in medicine FDM: Fused deposition modelling GIS: Guided implant surgery SLA: Stereolithography apparatus STL...

Discussion : CAD/CAM implant surgical guides

Discussion The purpose of a computer designed and computer manufactured (CAD/CAM) surgical guide is to provide the means for an accurate and reliable transfer of the computer-realised virtual treatment plan to the actual surgical field. The availability of the CBCT imaging modality should have led to an explosion of the usage of these guides, since they have been shown to be...

Results : CAD/CAM implant surgical guides

Results The range of the various maximum permissible errors due to the metal sleeve/osteotomy drill combination is presented in Table 1. Concerning the error at the apex, two reference tables were reported (Tables 2 and 3). In these tables, the deviation of the implant axis was also tabulated. A separate table (Table 4) tabulated the error at the neck. Multiple regression ...

Methods & Definition : CAD/CAM implant surgical gu...

Based on the geometric analysis of the problem in hand, an algorithm was developed and implemented in C programming language. The purpose of this program was to readily and accurately compute the following maximum positioning errors, permissible by the different sleeve/drill/guide properties (Fig. 2): 1. Deviation of the implant axis in degrees, 2. Error at the neck in mm, 2. Er...

Methods & Definition : CAD/CAM implant surgical gu...

Methods For the estimation of the errors in implant positioning due to the properties of the metal sleeve/osteotomy drill combination, four parameters are necessary: (1) sleeve length, (2) clearance (space between the bur and the sleeve), (3) implant length, and (4) offset (distance of the lip of the metal sleeve to the neck of the implant) (Figs. 1 and 2). Definitions Basic...

Background : CAD/CAM implant surgical guides

Background Computer-aided designed and computer-aided manufactured (CAD/CAM) implant surgical guides are long recommended to reliably transfer a virtual treatment plan to the surgical field. The 3d-printed guide stands a basic part of a process commonly referred to as guided implant surgery (GIS). The outcome of this process has been shown to be relatively accurate, even when th...

CAD/CAM implant surgical guides: maximum errors in...

CAD/CAM implant surgical guides: maximum errors in implant positioning attributable to the properties of the metal sleeve/osteotomy drill combination   Abstract Background The purpose of this study is to provide the relevant equations and the reference tables needed for calculating the maximum errors in implant positioning attributed to the properties of the mechanical parts of any CAD/CAM ...

Figure 3. Data from the VAS of patient-related out...

  Figure 3. Data from the VAS of patient-related outcome measures at the time of mounting of the implant-supported crown and at the final follow-up of the PRF and control group

Figure 2. Box plot of the radiographic peri-implan...

  Figure 2. Box plot of the radiographic peri-implant marginal bone level at different time points in millimeter. Baseline: the time of implant placement; abutment: the time of abutment operation; impression: the time of impression taking; follow-up: the time of the final follow-up

Figure 1. Intraoperative photos illustrating bone ...

  Figure 1. Intraoperative photos illustrating bone harvesting and lateral bone augmentation in the PRF group. Initially, an incision is made at the lateral aspect of the posterior part of the mandibular corpus (a) followed by exposing the mucoperiosteal flap (b), before making the osteotomy line (c). The bone block (d) is then retrieved before adjusted to the contour at the recipient site and...

Table 4 Patient-related outcome measures at baseli...

Table 4 Patient-related outcome measures at baseline and at the final follow-up   Test group Control group Difference p value Mean (95% CI) Mean (95% CI) Mean (95% CI) Baseline 9.44 (9.09 to 9.78) 9.57 (9.20 to 9.95) 0.13 (− 0.40 to 0.66) 0.61 Follow-up 9.66 (9.30 to 10.02) 9.55 (9.15 to 9.96) − 0.10 (-0.66 to 0.46) 0.71 Difference 0.22 (...

Table 3 Radiographic marginal bone level and clini...

Table 3 Radiographic marginal bone level and clinical recession on neighbouring tooth surface Group Baseline (mean, 95% CI) Follow-up (mean, 95% CI) Difference (mean, 95% CI) p value Radiographic marginal bone level in mm  Test 1.94 (1.50 to 2.38) 2.07 (1.64 to 2.51) − 0.14 (− 0.25 to − 0.02) p = 0.03  Control 2.34 (1.62 to 3.08) 2.49 (1.73...

Table 2 Radiographic peri-implant marginal bone le...

Table 2 Radiographic peri-implant marginal bone level in mm Test group Control group Mean difference 95% CI p value Obs Mean 95% CI Obs Mean 95% CI Baseline 14 − 0.24 − 0.48 to 0.00 13 − 0.28 − 0.52 to 0.03 0.04 − 0.314 to 0.39 p = 0.82 Abutment 14 0.07 − 0.17 to 0.30 13 − 0.01 − 0.26 to 0.25 0.08 − 0.278...

Table 1 Demographics and survival rates of implant...

Table 1 Demographics and survival rates of implants and implant crowns   Test group (PRF) Control group Number of implants 14 13 Mean age, years (range) 47.9 (23–66) 52.3 (24–72) Gender  Female 6 6  Male 8 7 Smokers Total 2 1   20 cigarettes per day 1 1 Number of implants 14 13 Implant length (mm) and imp...

Abbreviations & References: A clinical and radiogr...

Abbreviations ASC: Angulated screw channel BOP: Bleeding on probing DBBM: Deproteinised bovine bone mineral GBR: Guided bone regeneration ICC: Intraclass correlation coefficient KT: Keratinised peri-implant tissue PCR: Plaque control record PD: Probing depth PRF: Platelet-rich fibrin PROM: Patient-related outcome measures RCF: ...

Discussion: A clinical and radiographic study of i...

A minor, but statistically significant, radiographic bone loss occurred from baseline to the final follow-up at the neighbouring tooth surfaces in both groups. Moreover, both groups experienced a minor recession of the marginal gingiva from baseline to the final follow-up, but the change was not significant. Recession and the bone level of the neighbouring tooth surfaces to implants placed in ...

Discussion: A clinical and radiographic study of i...

The combination of the NobelParallel CC implant launched in 2015 and an abutment with ASC is relatively new and has so far been lined to only few mechanical problems [39, 40], among which rotation of the crown when torqueing the abutment screw was not stated. In both patients, a new implant was placed without any need for additional bone augmentation and without further complications. ...

Discussion: A clinical and radiographic study of i...

Discussion The present study focused on clinical and radiographic characteristics of staged implants placed in autogenous bone grafts covered by either a PRF membrane (PRF group) or a standard procedure (gold standard) involving coverage of the autogenous bone graft using a deproteinised bovine bone mineral and a resorbable collagen membrane (control group). The PRF group demonstrated a hi...

Results: A clinical and radiographic study of impl...

One patient (control group) expressed minimally changed extraoral sensation in the chin region at both the 1- and 2-week follow-up. However, the extra- and intraoral clinical examination revealed no sensory disturbances. The patient was not affected by this and described the same changed sensation at the final clinical follow-up after 29 months. Another patient (PRF group) experienced sensory d...

Results: A clinical and radiographic study of impl...

Radiographic peri-implant marginal bone change The mean peri-implant marginal bone level at the different time points is shown in Table 2 and Fig. 2. The mean marginal bone level at follow-up was 0.26 mm (95% CI: 0.01–0.50 mm) in the PRF group and 0.68 mm (95% CI: 0.41–0.96 mm) in the control group. The difference between the groups was − 0.43 mm (95% CI: − 0.80 to − 0....

Results: A clinical and radiographic study of impl...

Bleeding on probing The estimated probability or observed proportion of BOP for implants was 0.31 (95% CI: 0.14–0.70) in the PRF group and 0.30 (95% CI: 0.12–0.77) in the control group. The ratio of the probability of observing BOP was 1.046 (95% CI: 0.91–1.20), indicating that the probability of observing BOP is 4.6% higher in the PRF group than in the control group. No statistical differe...

Results: A clinical and radiographic study of impl...

Results Implant survival Two of the 27 initially placed implants were lost in the control group (Table 1). Twenty months after placement of the implant-supported crown, one implant (first premolar, regular platform (4.3 mm), length: 13 mm) was lost due to failed osseointegration. No periodontitis or peri-implant marginal bone resorption was obvious at the time of implant removal. A second...

Material & methods: A clinical and radiographic st...

The distance from the implant-abutment connection to the peri-implant marginal bone level was measured mesially and distally in parallel with the long axis of the implant using open-source software (ImageJ, National Institutes of Health, Bethesda, MD, USA). The distance from the cemento-enamel junction to the marginal bone level at the neighbouring tooth surfaces was also measured in parallel with...

Material & methods: A clinical and radiographic st...

Prosthodontic treatment Forty-nine days (range: 27–113 days) after placement of the healing abutment, the abutment was removed and the implant position was registered by an impression coping on the implant. The final implant-supported restoration was fabricated by using an individually designed angulated screw channel (ASC) zirconium abutment (Nobel Biocare®, Zürich, Switzerland) and venee...

Material & methods: A clinical and radiographic st...

  Methylprednisolone was prescribed the following morning (16 mg) and evening (16 mg). Additionally, postoperative ibuprofen (400 mg, four times daily) and paracetamol (1000 mg, four times daily) were prescribed for 1 week. The patients were instructed to rinse with 0.12% chlorhexidine digluconate twice daily and discontinue the use of their prostheses (if any). Patients were seen for ...

Material & methods: A clinical and radiographic st...

The bone graft was retrieved by making a continuous osteotomy line with a cylindrical and a round bur at the lateral part of the mandible, with a uniform size of approximately 15 × 25 mm (Fig. 1c, d). The bone block containing mainly cortical bone was then gently separated from the mandible using a raspartorium. The block graft was covered with a saline-moistened gauze until used. In the PRF g...

Material & methods: A clinical and radiographic st...

At the time of the bone augmentation procedure, two patients (14%) in the PRF group and one (8%) patient in the control group were smokers. Patients were partially edentulous due to trauma (n = 22), agenesis (n = 3) or marginal periodontitis [2]. Two patients were unavailable for the final follow-up. The referring dentist followed the non-attenders, and telephone interview revealed no subjective o...

Material & methods: A clinical and radiographic st...

Material and methods   The study was performed according to the Declaration of Helsinki and internationally accepted guidelines for RCT, including the CONSORT statement (www.consort-statement.org). The volumetric changes of the augmented bone [26], the histological composition of the augmented bone [27] and pain after the primary bone augmentation procedure [28] were previously described in d...

Background: A clinical and radiographic study of i...

Despite the shape of a membrane, the PRF membrane does not have the properties of a resorbable barrier membrane [21, 22], due to its fast degradation in the same manner as a natural blood clot (1–2 weeks) [23]. Therefore, the PRF membrane is not believed to replace a barrier membrane in the classic understanding of guide bone regeneration (GBR), but rather to enhance the healing capacity of t...

Background: A clinical and radiographic study of i...

Background Implant-supported single crowns are characterised by high long-term survival and few biological and technical complications, which typically includes peri-implant marginal bone loss, screw-loosening and fracture of veneering material complications [1,2,3]. To achieve a successful treatment outcome, the implants must be inserted in sufficient bone volume of an adequate quality to obta...

A clinical and radiographic study of implants plac...

A clinical and radiographic study of implants placed in autogenous bone grafts covered by either a platelet-rich fibrin membrane or deproteinised bovine bone mineral and a collagen membrane: a pilot randomised controlled clinical trial with a 2-year follow-up   Abstract Purpose To compare the survival and clinical performance of implants placed in sites previously augmented with autogenous ...

Figure 17. polythene “washer”

  Figure 17. The appearance of the case shown in Fig. 16 with the polythene “washer” removed at 2 weeks post-surgery, providing access to the zygomatic oncology implants

Figure 15. Facial appearance 18 months following ...

Figure 15. Facial appearance 18 months following treatment Figure 15. Facial appearance 18 months following treatment

Figure 14. Intra-oral view of perforated flap 3 we...

Figure 14. Intra-oral view of perforated flap 3 weeks following radiotherapy

Figure 13. Panoramic dental radiograph showing the...

  Figure 13. Panoramic dental radiograph showing the position of the zygomatic implants and the seating of the initial fixed prosthesis

Figure 12. Provisional acrylic fixed dental prosth...

  Figure 12. Provisional acrylic fixed dental prosthesis fitted at 4 weeks post-surgery

Figure 11. Intra-oral view of the soft tissue flap

Figure 11. Intra-oral view of the soft tissue flap at 3 weeks post-operatively with overgrowth of flap over the zygomatic oncology implants

Figure 10. Radial forearm flap inset and sutured i...

Figure 10. Radial forearm flap inset and sutured into the maxillary defect and perforated by the zygomatic oncology implant abutments Figure 10. Radial forearm flap inset and sutured into the maxillary defect and perforated by the zygomatic oncology implant abutments

Figure 9. Inter-occlusal registration using the pr...

  Figure 9. Inter-occlusal registration using the pre-fabricated maxillary denture prosthesis relined with silicone putty over the implant abutment protection caps

Figure 8. Abutment level impression utilising ligh...

Figure 8. Abutment level impression utilising light-cured acrylic tray material

Figure 7. Conventional zygomatic implant insertion

  Figure 7. Conventional zygomatic implant insertion on the non-defect side of the maxilla following extraction of the remaining teeth and an alveoloplasty

Figure 6. Zygomatic oncology implants sited in the...

Figure 6. Zygomatic oncology implants sited in the residual zygomatic bone on the defect side of the maxilla

Figure 5. Left-sided maxillary resection (Brown cl...

Figure 5. Left-sided maxillary resection (Brown class 2b)  

Figure 4. Panoramic dental radiograph showing dent...

  Figure 4. Panoramic dental radiograph showing dental status at presentation

Figure 3. Staging CT scan confirming maxillary des...

  Figure 3. Staging CT scan confirming maxillary destruction but preservation of the orbital floor

Figure 2. Staging MRI scan showing destructive les...

Figure 2. Staging MRI scan showing destructive lesion left maxilla

Figure 1. Clinical view of left-sided maxillary tu...

Figure 1. Clinical view of left-sided maxillary tumour at presentation

Table 1 Patient-reported quality of life outcomes ...

Table 1 Patient-reported quality of life outcomes following ZIP flap procedure From: The zygomatic implant perforated (ZIP) flap: a new technique for combined surgical reconstruction and rapid fixed dental rehabilitation following low-level maxillectomy Domain Score Activity 100 (“I am as active as I have ever been”) Anxiety 100 (“I am not anxious about ...

References: The zygomatic implant perforated (ZIP)...

References Okay DJ, Genden E, Buchbinder D, Urken M. Prosthodontic guidelines for surgical reconstruction of the maxilla: a classification system of defects. J Prosthet Dent. 2001;86(4):352–63. Rohner D, Bucher P, Hammer B. Prefabricated fibular flaps for reconstruction of defects of the maxillofacial skeleton: planning, technique, and long-term experience. Int J Oral Maxillofac Impl...

Conclusions: The zygomatic implant perforated (ZIP...

Conclusions The ZIP flap technique represents an innovative approach to the management of patients presenting with low-level malignant maxillary tumours. It provides effective closure of the resulting maxillary defect restoring speech and swallowing functions and also establishing a high-quality fixed dental rehabilitation in a rapid timescale, thus facilitating a more timely return to function...

Discussion: The zygomatic implant perforated (ZIP)...

Immediate/early loading of zygomatic [8] and dental implants [9] have been well demonstrated already within the literature with very high implant survival rates. In the oncology setting, Boyes-Varley et al. [4] lost no zygomatic/oncology implants in their series of 20 patients restored with implant-retained obturators, 6 of whom received radiotherapy post-operatively. The case reported...

Discussion: The zygomatic implant perforated (ZIP)...

The use of soft tissue flaps to close a typical hemi-maxillectomy defect is an effective way of dealing with the oro-nasal communication, but in isolation, this technique works against dental rehabilitation as the bulk of the flap provides a very poor moveable foundation for a subsequent removable prosthesis. The move towards the use of composite reconstruction (especially the fibula flap) h...

Discussion: The zygomatic implant perforated (ZIP)...

Discussion In order to reduce intra-operative time, the soft tissue free flap is harvested at the same time as the implant placement and prosthodontic procedures. On raising a skin island, it is appropriate to make it a little over-sized for the required defect to ensure that tension and possible dehiscence at the surgical margins during healing is reduced. In low-level maxillectomy (Brown...

Procedural modifications to the ZIP flap technique

Procedural modifications to the ZIP flap technique In order to address some of the issues highlighted in this early case, the technique was modified slightly to try and prevent flap overgrowth and prosthesis fracture in the early stages. In order to prevent flap overgrowth over the zygomatic oncology implant abutments, the use of a polythene washer was instituted on subsequent cases treated in th...

The ZIP flap technique (2)

The radial forearm free flap (RFFF) was then disconnected from the arm and inset into the maxillary defect after creating a tunnel down into the left neck for the pedicle. The flap was carefully perforated over the zygomatic implant abutment protection caps using a short incision just through the skin layer followed by blunt dissection to allow the abutment and cap to perforate the flap ensuring a...

The ZIP flap technique (1)

The ZIP flap technique The patient underwent tracheostomy, a limited left-sided selective neck dissection for node sampling and vessels preparation. The maxillary tumour was excised in a standard manner via an intra-oral approach with preservation of the left orbital floor (Fig. 5). The resection extended to the maxillary alveolar midline in the incisor region with extension posteriorly just into...

Case : The zygomatic implant perforated (ZIP) flap

Case presentation A 66-year-old male patient presented with an enlarging mass in the left maxilla (Fig. 1). The mass had been present for a few weeks. An incisional biopsy revealed squamous cell carcinoma. Staging scans were undertaken (Fig. 2) which demonstrated a T4N0M0 maxillary alveolus tumour in close proximity to the left orbital floor with obliteration of the maxillary antrum and destruc...

Background : The zygomatic implant perforated (ZIP...

Background The surgical management and prosthodontic rehabilitation of the maxillectomy patient is complex with a variety of options available to the head and neck cancer team ranging from simple prosthodontic obturation [1] to reconstruction using pre-fabricated or digitally planned composite flaps [2] with or without the placement of osseointegrated implants [3]. The primary aims of treatment...

The zygomatic implant perforated (ZIP) flap

The zygomatic implant perforated (ZIP) flap: a new technique for combined surgical reconstruction and rapid fixed dental rehabilitation following low-level maxillectomy Abstract This aim of this report is to describe the development and evolution of a new surgical technique for the immediate surgical reconstruction and rapid post-operative prosthodontic rehabilitation with a fixed dental prost...

Figure 2. Three implants were embedded in an artif...

  Figure 2. Three implants were embedded in an artificial mandible    

Figure 1. Breakdown of respondents. The retrieval ...

  Figure 1. Breakdown of respondents. The retrieval rate was approximately 40% in each of the three societies

Table 8 Survey of dentists who offer implant treat...

Table 8 Survey of dentists who offer implant treatment (671 dentists). “Do you use the implant card?”     The number of respondents The card developed by the Japanese Society of Oral Implantology 54 (8%) The pocket notebook developed by the Japanese Academy of Maxillofacial Implants 11 (2%) Implant card developed by manufacturers 133 (20%) Unique...

Table 6 Methods to identify the presence of implan...

Table 6 Methods to identify the presence of implants in patients receiving home-visit dental care     The number of respondents Visual inspection 153 (53%) Radiography 49 (17%) Information provided by patients or their families 88 (30%) Ask patients’ dentists 10 (3%) Implant card 5 (2%) Dental records of implant surgeries that I perform...

Table 5 Number, implants, and oral self-care of pa...

Table 5 Number, implants (whether placed by the visiting dentist), and oral self-care of patients receiving home-visit dental care seen by dentists who provided home-visit dental care over the past 12 months (291 dentists, 4,569 institutions)     Total number of patients Patients with implants Patients with implants placed by the visiting dentist Total number of pat...

Table 3 Have you been consulted by your implant pa...

Table 3 Have you been consulted by your implant patients or their families about oral health management when the patients were admitted to the hospital or became bedridden?     The number of respondents Yes, I have 150 (22%) No, have not 513 (76%) No answer 8 (1%)

Table 4 If you are informed by one of your implant...

Table 4 If you are informed by one of your implant patients that s/he cannot visit your clinic due to becoming bedridden, how do you address this?     The number of respondents I’ll do nothing 34 (5%) I’ll ask another dentist to provide the patient with home-visit dental care 217 (32%) I’ll advice the patient to perform oral self-care only 111 (17%)...

Table 2 Among the patients who received implant tr...

Table 2 Among the patients who received implant treatment at your clinic, are there any patients who were admitted to the hospital or became bedridden at home?     The number of respondents Yes, there is 204 (30%) No, there isn’t 182 (27%) I don’t know 278 (41%) No answer 7 (1%)

Table 1 Survey questions

Table 1 Survey questions 1. Do you offer implant treatment? 2. Do you give a “card/pocket notebook” to patients for whom implant treatment has been completed? 3. Among the patients who received implant treatment at your clinic, are there any patients who were admitted to the hospital or became bedridden at home? 4. Have you been consulted by your implant patient...

References : A preliminary report on dental implan...

References Statistic Bureau of Japan, Population Estimates (December 2016), http://www.stat.go.jp/english/data/jinsui/tsuki/index.htm. Accessed 3 Mar 2018. Outline of the Status of Insured Long-Term Care Service, Ministry of Health, Labour and Welfare (Preliminary version April 2016), http://www.mhlw.go.jp/topics/kaigo/osirase/jigyo/m16/dl/1604a.pdf. Accessed 3 Mar 2018. Survey of Denta...

Discussion : A preliminary report on dental implan...

Discussion Questionnaire survey by post mail had been said to be low retrieval rate, but it was considered to be suitable for information response of many clinics and hospitals. In this research, a questionnaire survey was conducted for representative members or dental specialists of three academic societies who are likely to understand the significance of the research and are thought to be...

Results : A preliminary report on dental implant c...

Results Of the 924 dentists participating in the survey, 465 respondents (50%) offer implant treatment only and 85 respondents (9%) provide home-visit dental care only. Two hundred and six respondents (22%) provide both implant treatment and home-visit dental care (Fig. 2). The number of dentists who provide home-visit dental care was significantly lower among those who offer implant treatment (p...

Methods : A preliminary report on dental implant c...

Methods The survey was conducted during 3 months from August to October 2015 by non-anonymous questionnaire (four pages on A4 paper) including questions developed by the authors of the present study (Table 1). The survey sheets were sent and collected by post mail. The target population of the survey was 2339 representative members or dental specialists belonging to any of the following three or...

Review : A preliminary report on dental implant co...

Review Background In September 2016, Japan’s graying population reached a level where 27.3% (34.61 million) of the total population was 65 years or older, as announced by the Statistics Bureau of the Ministry of Internal Affairs and Communications. Of the older adults, over 6 million people or approximately 20% require long-term care. These elderly people have difficulty attending clinics, w...

A preliminary report on dental implant condition

A preliminary report on dental implant condition among dependent elderly based on the survey among Japanese dental practitioners Abstract Background The objective of this study was to ascertain the situation relevant to implants, the status of oral self-care, the status of aftercare provided by the dentist who placed the implant, and the usage status of the implant card, in homebound or insti...

Figure 4. Bone implant contact of different test g...

  Figure 4. Bone implant contact of different test groups

Figure 3. Stained histomorphometric section

Figure 3. a Stained histomorphometric section demonstrating bone implant contact of uncoated zirconia implant. b Stained histomorphometric section demonstrating bone implant contact of HA–hybrid–zirconia surface. c Stained histomorphometric section demonstrating bone implant contact of PRP–hybrid–zirconia surface Figure 3. a Stained histomorphometric section demonstrating bone...

Figure 2. SEM image, ×10,000, demonstrating the c...

Figure 2. a SEM image, ×10,000, demonstrating the characteristic porous surface of selective infiltration etching surface of zirconia. b SEM image, ×500, demonstrating deposition of PRP coat and complete filling of the porous surface. c SEM image, ×500, demonstrating filling of the porous surface with particles of HA Figure 2. a SEM image, ×10,000, demonstrating the characteristic...

Figure 1. Mercury porosimetry and the average pore...

  Figure 1. a Mercury porosimetry and the average pore diameter of the prepared implants. b EDX analysis of hybrid–zirconia surface showing peaks of zirconia, calcium, and phosphate. Ca/P ratio is 1.67. c XRD peaks of uncoated and bioactive implants showing characteristic peaks specific for tetragonal yttrium zirconium oxide crystal system represented by (101), (112), (200), and (211) a...

References : Bioactive–hybrid–zirconia implant...

References Pye AD, Lockhart DEA, Dawson MP, et al. A review of dental implants and infection. J Hosp Infect. 2009;72:104–10. Heydecke G, Thomason JM, Lund JP, Feine JS. The impact of conventional and implant supported prostheses on social and sexual activities in edentulous adults: results from a randomized trial 2 months after treatment. J Dent. 2005;33:649–57. Albrektsson T, Branema...

Discussion : Bioactive–hybrid–zirconia implant...

Discussion Several techniques were previously tested for coating hydroxyl apatite particles in the surface of implants as the following: thermal (plasma) spraying, dipping coating, electrochemical deposition, sputter coating, pulsed laser deposition, and sol-gel technique. Many parameters determined the performance of HA coating both in vitro and in vivo, including chemical composition, crystal...

Results : Bioactive–hybrid–zirconia implant su...

Results Mercury porosimetry revealed comparable (F = 0.047, P 

Methods : Bioactive–hybrid–zirconia implant su...

Methods Preparation of zirconia implants CAD/CAM zirconia milling blocks (NobelBiocare, Göteborg, Sweden) were used for preparation of zirconia implants (cylinders 3.7 mm × 8 mm). The milled implants were sintered according to manufacturer recommendations (1350 °C for 6 h). To produce a nano-porous surface, all specimens were subjected to selective infiltration etching (SIE) techniq...

Background : Bioactive–hybrid–zirconia implant...

Background Dental implants became one of the most reliable techniques used to restore missing teeth. Material composition and surface topography play a fundamental role in osseointegration. Therefore, various chemical and physical surface modifications have been developed to improve osseous healing around the inserted implants. Two main approaches have been suggested to improve surface properti...

Bioactive–hybrid–zirconia implant surface

Bioactive–hybrid–zirconia implant surface for enhancing osseointegration: an in vivo study Abstract Background Zirconia is characterized by a hard, dense, and chemically inert surface which requires additional surface treatments in order to enhance osseointegration. The proposed hypothesis of the study was that combination of a nano-porous surface infiltrated with a bioactive material may...

Figure 10. Patient 1—post-operative evaluation o...

  Figure 10. Patient 1—post-operative evaluation of placement accuracy of the implants in the mandible. Green is the planned position; blue is the actual position

Figure 9. Patient 1—prosthodontic end result 5 m...

  Figure 9. Patient 1—prosthodontic end result 5 months after implant placement

Figure 8. Patient 2—intra-oral situation during ...

  Figure 8. Patient 2—intra-oral situation during orthodontic treatment at the age of 14. A temporary crown with bracket is fixed on the dental implant. Eight months after start of orthodontic treatment, the 34 is already close to the planned end position

Figure 7. Patient 2—post-operative orthopantomog...

  Figure 7. Patient 2—post-operative orthopantomogram (OPT) at age of 13. Situation 10 months after implant placement. Three months after starting the orthodontic treatment, the 34 is already erected

Figure 6. Patient 1—post-operative orthopantomog...

  Figure 6. Patient 1—post-operative orthopantomogram (OPT) at age of 18

Figure 5. a Drilling templates of patient 1

  Figure 5. a Drilling templates of patient 1. Printed model of the maxilla (left) and mandible (right) with drilling template and metal drilling inserts (Nobel biocare). b Drilling template for the mandible of patient 1. c Implant placement of patient 1. Dental implant placement in the mandible using the virtual developed tooth-supported templates and metal drilling inserts

Figure 4. a Patient 1—virtual set-up of the ult...

  Figure 4. a Patient 1—virtual set-up of the ultimate treatment goal. b Patient 2—virtual set-up of the ultimate implant position. One short dental implant was planned in region 35, based on the location of the mandibular nerve (orange), the impacted 34 (pink) and the bone quality and volume. c Patient 2—virtual set-up of the ultimate prosthetic treatment goal

Figure 3. a Patient 1—detailed 3D model of the ...

  Figure 3. a Patient 1—detailed 3D model of the combined data from the CBCT and intra-oral scan at age of 18. b Patient 2—detailed 3D model of the combined data from the CBCT and intra-oral scan at age of 12

Figure 2 a Patient 2—pre-implant orthopantomogr...

  Figure 2 a Patient 2—pre-implant orthopantomogram (OPG) at the age of 12. Situation before start of orthodontic and implant treatment. Eleven permanent teeth (including 2 third molars) were congenitally missing and the 34 is impacted. To erect the 34, orthodontic treatment was desired. Due to the lack of stable anchorages in the third quadrant, it was decided to place one implant at tooth...

Figure 1. Patient 1—orthopantomogram (OPT) at ag...

    Figure 1. a Patient 1—orthopantomogram (OPT) at age of 13. Situation before extraction of the ankylosed deciduous teeth 55, 54, 65, 74, 75, 84, and 85 and start of orthodontic treatment. Eleven permanent teeth (including 4 third molars) were congenitally missing. b Patient 1—post-orthodontic situation at age of 16. The top of the mandibular processus alveolaris is small (upper). T...

Results : Three-dimensional computer-guided implan...

Results Clinical and radiographic assessments The surgical guides fitted well and facilitated implant placement. All implants were placed in the native bone. No dehiscences of the implant surface occurred. Post-operative orthopantomograms (OPT) of patients 1 and 2 are shown in Figs. 6 and 7. In patient 1, six implants were placed (NobelParallel Conical Connection implants, Nobel Biocare Ho...

Methods : Three-dimensional computer-guided implan...

Patient and methods Implant planning and placement Pre-implant procedure and 3D planning A CBCT (ICat, Image Sciences International, Hatfield, UK; 576 slices, voxel size 0.3 mm, FOV: 11 × 16 cm) was made of two oligodontia patients (for patient details, see Figs. 1 and 2) for implant planning. Detailed patient information was obtained with regard to the nerve position and bone quality an...

Introduction : Three-dimensional computer-guided i...

Introduction Oligodontia is the congenital absence of six or more permanent teeth, excluding third molars [1]. The need for oral rehabilitation in patients with oligodontia is high as they often suffer from functional and aesthetic problems due to a high number of missing teeth. Implant-based prosthodontics seem to be favourable to improve oral function and aesthetics in oligodontia [2]. Impla...

Three-dimensional computer-guided implant placemen...

Three-dimensional computer-guided implant placement in oligodontia Abstract Background The aim of computer-designed surgical templates is to attain higher precision and accuracy of implant placement, particularly for compromised cases. Purpose The purpose of this study is to show the benefit of a full three-dimensional virtual workflow to guide implant placement in oligodontia cases where t...

Figure 1. Flow diagram

Figure 1. Flow diagram Figure 1. Flow diagram

Table 5 Average differences in BoP, SoP, and PPD b...

Table 5 Average differences in BoP, SoP, and PPD between the control and test group at 3-month follow-up Outcome variable Crude modelaβ (95% CI) p value Adjusted modelbβ (95% CI) p-value % Sites BoP% Sites SoPMean PPD 16.2 (−7.9 to 40.3)0.0 (−10.9 to 10.9)0.6 (−0.6 to 1.8) 0.7431.0000.205 7.9 (−16.4 to 32.3)0.7 (−10.1 to 11.4)0.2 (−1.0 to 1.3) 0.8210.882...

Table 4 Descriptive statistics of clinical paramet...

Table 4 Descriptive statistics of clinical parameters     Control Test T0 (n = 22) T3 (n = 20) T0 (n = 31) T3 (n = 30) Plaque % of sites (SD)% of implants (n) 4.5 (12.5)13.6 (3) 10.0 (18.8)25.0 (5) 4.0 (9.3)16.1 (5) 2.5 (7.6)9.7 (3) BoP % of sites (SD)% of implants (n) 86.4 (18.5)100 (22) 28.8 (35.6)50 (10) 66.1 (29.3)96.8 (30) 39.2 (31.3...

Table 3 Log-transformed mean bacterial anaerobic c...

Table 3 Log-transformed mean bacterial anaerobic counts (SD) for the control and test group before (T0) and 3 months after (T3) the surgical treatment (paperpoint samples) N = 47a Total anaerobic bacterial loadLog-transformed mean (SD)   T0 T3 Difference β (95% CI)b p value Control 6.69 (1.32) 6.31 (1.30) 0.38 (1.36) −0.26 (−0.84–0.33) 0.377 ...

Table 2 Log-transformed mean bacterial anaerobic c...

Table 2 Log-transformed mean bacterial anaerobic counts (SD) of culture-positive implants for the control and test group before (Tpre) and after (Tpost) debridement and decontamination of the implant surface (intra-operative microbrush samples) N = 40a Total anaerobic bacterial loadLog-transformed mean (SD)   Tpre Tpost Difference β (95% CI)b p value Control 5.57 ...

Table 1 Characteristics of included patients/impla...

Table 1 Characteristics of included patients/implants Characteristics Control Test Number of patients 14 14 Age (years; mean [SD]) 57.0 (13.7) 60.9 (7.2) Gender; M (male), F (female) M5, F9 M7, F7 Smoking; n subjects (%) 1 (7%) 3 (21%) History of periodontitis; n subjects (%) 4 (29%) 5 (36%) Dental status; n subjects (%) - Partially edentul...

References : Implant decontamination with phosphor...

References Lang NP, Berglundh T, Working Group 4 of Seventh European Workshop on Periodontology. Periimplant diseases: where are we now?—Consensus of the Seventh European Workshop on Periodontology. J Clin Periodontol. 2011;38(Suppl):11,178–181. Derks J, Tomasi C. Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol. 2015;42:158–71. Derks ...

Discussion : Implant decontamination with phosphor...

The residual biofilm area was significantly greater after treatment with phosphoric acid compared to air abrasive treatment with powder or even control treatment without powder. Apparently, only water and air might be effective in reducing the biofilm. Nonetheless, when the titanium surface was viewed under a scanning electron microscopy (SEM), no visible titanium surface change was seen aft...

Discussion : Implant decontamination with phosphor...

A gel as application mode has the great advantage of being precisely applicable with minimal touching of the surrounding bone or connective tissue. A disadvantage of a gel might be the limited flow in deeper areas of the rough implant surface. To overcome this problem, it was decided to continuously rub the etching gel onto the implant surface with a small brush during the decontamination pe...

Discussion : Implant decontamination with phosphor...

Discussion This randomized controlled trial aimed to determine the effect of 35% phosphoric etching gel on decontamination of the implant surface during resective surgical treatment of peri-implantitis. Both decontamination procedures (mechanical debridement with curettes and gauzes combined with phosphoric acid 35% and mechanical debridement combined with sterile saline) resulted in a sign...

Results : Implant decontamination with phosphoric ...

Clinical outcomes Descriptive statistics of the clinical outcomes at baseline and follow-up are depicted in Table 4. At 3-month follow-up, 75% of the implants (66.7% of the patients) in the control group and 63.3% of the implants (53.8% of the patients) in the test group showed no clinical signs of inflammation (PPD ≤4 mm without bleeding and/or suppuration on probing) (Table 4). The results...

Results : Implant decontamination with phosphoric ...

Results The progress of patients throughout the different phases of the study is illustrated in Fig. 1. Table 1 depicts the baseline demographic patient and implant characteristics. The included patients had a total of 128 implants of which 53 implants showed signs of peri-implantitis. Different implant brands and types with different implant surfaces were present, including Straumann (Strauman...

Statistical analysis : Implant decontamination wit...

Assuming a two-sided two sample t test with a significance level (α) of 0.05 and a power (β) of 80% required a sample size of 34 implants. A 20% compensation for dropouts was taken into account (34/0.8 = 42.5 implants). Based on a previous study [10], it was expected that not all baseline microbiological samples would yield a detectable number of cultivable bacteria ([10], 19 out of 79 =...

Randomization : Implant decontamination with phosp...

Peri-implant pocket depth was measured at four sites per implant (mesial, buccal, distal, and lingual) using a pressure sensitive probe (KerrHawe Click Probe®, Bioggo, Switzerland) (probe force of 0.25 N). Bleeding and suppuration were scored up to 30s after pocket probing. Microbiological peri-implant sulcus samples were collected from each implant with peri-implantitis using four sterile paper...

Outcomes : Implant decontamination with phosphoric...

Angular bony defects were eliminated, and bone was recontoured using a rotating round bur under saline irrigation. Mucosal flaps were apically positioned and firmly sutured (Vicryl Plus® 3-0; Ethicon Inc., Somerville, NJ, USA), and suprastructures were re-positioned. For both control and test group, surgery was followed by 2 weeks of mouth rinsing with 0.12% CHX + 0.05% CPC without alcohol t...

Interventions : Implant decontamination with phosp...

Interventions The study protocol was based on the study protocols of two previous studies evaluating the decontaminating effect of chlorhexidine during surgical peri-implantitis treatment [10, 32] and is briefly described below. Within 1 month before surgical treatment, all patients received extensive oral hygiene instructions and mechanical non-surgical debridement of implants and remaining de...

Methods : Implant decontamination with phosphoric ...

Methods Trial design The present study is a double-blind randomized controlled trial evaluating the effect of 35% phosphoric etching gel (test group) compared to the effect of saline (control group) for implant surface decontamination combined with mechanical debridement during surgical peri-implantitis treatment. Patients were randomly assigned to the test or control group using a one-to-one al...

Background : Implant decontamination with phosphor...

Background Triggered host defense responses initiate inflammation of the peri-implant soft tissue (peri-implant mucositis), which can lead to loss of peri-implant supporting bone (peri-implantitis), and eventually, result in implant failure [1]. An increasing prevalence of peri-implantitis has been described in recent literature [2], with current incidence ranging from 1 to 47%. A non-linear, acc...

Implant decontamination with phosphoric acid

Implant decontamination with phosphoric acid during surgical peri-implantitis treatment: a RCT Abstract Background Peri-implantitis is known as an infectious disease that affects the peri-implant soft and hard tissue. Today, scientific literature provides very little evidence for an effective intervention protocol for treatment of peri-implantitis. The aim of the present randomized controlled t...

Figure 5. Florescence microscopy

  Figure 5. a Florescence microscopy showing H33258-stained MC3T3-E1 cells on Ankylos® and 3M™ESPE™ MDI disks. Although equal numbers of cells were plated, after 12 days of culture, more cells were detected on the 3M™ESPE™ MDI disks. b Increased Alamar blue® reduction in MC3T3-E1 cells seeded on 3M™ESPE™ MDI disks when compared to cells cultured on Ankylos®. c Increase...

Figure 4. a C2C12 cells (control) and pBMP-2-tran...

  Figure 4. a C2C12 cells (control) and pBMP-2-transfected C2C12 cells were seeded on a 24-well plate (50,000 cell/well) and cultured in DMEM medium for 48 h. ALPL assay showing upregulated ALPL activity in the BMP-2-transfected C2C12 cells. b Cell extracts of C2C12 cells and pBMP-2-transfected cells were run on a 10% SDS-PAGE under non-denaturing conditions. The gel was then stained with ...

Figure 3. Increased proliferation of C2C12 cells g...

  Figure 3. Increased proliferation of C2C12 cells grown on 3M™ESPE™ MDI disks in comparison to the cells grown on the Ankylos® disks untreated and treated with bone morphogenetic protein-BMP-2

Figure 2. Implant surface characterization under S...

    Figure 2. Implant surface characterization under SEM. Increased surface roughness in the 3M™ESPE™ MDI dental implants when compared to Ankylos® implants

Figure 1. Preparation of specimens

  Figure 1. Preparation of specimens. Small disks represent 3M™ESPE™ MDI implants, and large disks represent Ankylos® implants. Note that the attachment of polystyrene rings ensures the area of culture remains constant regardless of the disk size

Discussion : Comparison of two titanium dental imp...

MacDonald et al. have shown that wettability, i.e., hydrophilic surfaces support cell interactions and biological fluids better than the hydrophobic surfaces. It has also been shown that roughening the titanium surface improves hydrophilicity. In addition, many authors have stated that rougher surfaces promote differentiation, growth and attachment of bone cells, and higher production of gro...

Discussion : Comparison of two titanium dental imp...

Because of their pluripotency, these cells have been considered as a type of mesenchymal stem cells. It has been shown that when treated with BMPs, these cells readily upregulate many key osteoblast markers including RUNX2, OSX, osteocalcin, and alkaline phosphatase (ALPL). In the current study, we used C2C12 cells that were treated with BMP-2 or stably transfected with a BMP-2 expression v...

Discussion : Comparison of two titanium dental imp...

Discussion In the current study, we used an in vitro cell culture system to evaluate the biocompatibility of two implant materials with different surface topography. Our objective was to establish the osseointegration potential of MDIs versus an established regular implant. Disks prepared from the implant material were coated with gelatin to grow cells, and proliferation and osteogenic diff...

Methods : Comparison of two titanium dental implan...

  Alkaline phosphatase immunostaining and assay BMP-2-transfected C2C12 cells were fixed in 4% PFA for 15 min, and then blocked with 5% bovine serum albumin (Fisher, Pittsburgh, PA, USA) in Tris buffered saline-0.025%Triton for 30 min at room temperature, followed by overnight incubation with an anti-mouse alkaline phosphatase antibody (R&D systems, Minneapolis, MN, USA). Detection was done by ...

Methods : Comparison of two titanium dental implan...

The reduction of Alamar blue was measured at 560 nm (reference wavelength 610 nm) after 5-h incubation at 37 °C using a microplate reader (Infinite 200, Tecan). Generation of BMP2 expressing C2C12 cells C2C12 cells were electroporated together with 0.4 μg of a BMP-2 expression vector (a kind gift from Dr. Katagiri) and 0.1 μg of pCMV-Tag, which expresses a neomycin-resistance gene. Culture...

Results : Comparison of two titanium dental implan...

Results Ring culture technique The variable sizes of the implant disks obtained from two different manufacturers demanded an innovative culture system to ensure equal surface areas on both disks for the cell culture experiments. We achieved this by attaching constant diameter (5 mm) plastic cylinders to the disk surface. Disks were sterilized with absolute alcohol, and polystyrene cloning cyli...

Methods : Comparison of two titanium dental implan...

Methods Implant disks Titanium disks made up with the same materials and surface characteristics as those with the original implants were obtained from the respective manufacturers. Two types of disks were used; the small disks represented 3M™ESPE™ MDI implants, while the large disks represented Ankylos®, Dentsply Friadent implants. A total of 10 disks of each brand were used for the stud...

Background : Comparison of two titanium dental imp...

Background Prosthetic devices are often used as surrogates for missing skeletal and dental elements. These devices are in close contact with the surrounding tissues, and their functionality and stability are critically dependent on the successful integration within the tissue’s extracellular matrix (ECM). The surface of the implanted device directly interacts with cell and extracellular milie...

In vitro comparison of two titanium dental implant...

In vitro comparison of two titanium dental implant surface treatments: 3M™ESPE™ MDIs versus Ankylos® Abstract Background An ideal implant should have a surface that is conducive to osseointegration. In vitro cell culture studies using disks made of same materials and surface as of implants may provide useful information on the events occurring at the implant-tissue interface. In the curr...

Table 2 Insertion torque (IT), removal torque (RT)...

Code IT(N•cm) RT(N•cm) ISQ 12S 13.67 (1.88) 11.68 (1.06) 51.40 (2.95) 06D 20.19 (1.61) 17.45 (1.28) 53.77 (2.73) 06S 22.30 (1.78) 20.25 (2.47) 55.66(1.62)

Table 1 Dimensions of implants

Implant code Thread type Pitch (mm) Lead (mm) Lead angle (degree) Total thread length (mm) 12S Single-threaded 1.2 1.2 8.1 64 06D Double-threaded 0.6 1.2 8.1 129 06S Single-threaded 0.6 0.6 4.65 129

Figure 6. Bone debris at the contact interfaces

  Figure 6. Bone debris at the contact interfaces. a Numbers of debris particles. b Number and size of debris particles. Each dot indicates a debris particle, and dashes indicate median particle sizes. Particle sizes: small, < 1000 μm2; medium, 1000–10000 μm2, and large, ≥ 10,000 μm2. c Particle size distribution

Figure 5. Microscopic analysis of contact interfac...

  Figure 5. Microscopic analysis of contact interfaces. Microscopic observations of the artificial bone-implant and number of debris particles. The small arrows in the panel indicate voids in the implant-bone interface

Figure 4. Torque kinetics. Immediately after inser...

  Figure 4. Torque kinetics. Immediately after insertion terminated, the implant was removed using the same load and rotation speed. Torque kinetics were measured during implant insertion (top) and removal (bottom)

Figure 3. Comparison between IT and RT

  Figure 3. Comparison between IT and RT. Maximum IT value was measured when insertion was terminated. Immediately after insertion, the implant was removed, and the RT value was measured when removal commenced

Figure 2. Insertion torque (IT), removal torque (R...

  Figure 2. Insertion torque (IT), removal torque (RT), and implant stability quotient (ISQ)  

Figure 1. Implant code 12S

Figure 1. Implants. Implant code 12S is similar to a commercially available standard single-threaded implant with equal thread pitch and a 1.2-mm lead. The thread length of implant code 06D is doubled by adding the second thread (light blue). The thread length of implant code 06S is doubled by a 50% reduction in pitch and lead angles. Characteristics of each implant are summarized in Table 1 Fi...

References : Effects of implant thread design on p...

References Javed F, Ahmed HB, Crespi R, Romanos GE. Role of primary stability for successful osseointegration of dental implants: factors of influence and evaluation. Interv Med Appl Sci. 2013;5:162–7. Falco A, Berardini M, Trisi P. Correlation between implant geometry, implant surface, insertion torque, and primary stability: in vitro biomechanical analysis. Int J Oral Maxillofac Implan...

Discussion : Effects of implant thread design on p...

Although bone models composed of a combination of cortical and cancellous bone are also available, this study used a single bone model with a homogeneous density to eliminate any effect of cortical bone and evaluate only the effect of design features on torque and ISQ values. Experimental implant placement using artificial bone models is generally conducted to si...

Discussion : Effects of implant thread design on p...

Clinicians are advised to recognize the risk associated with using a multithreaded implant with a high lead angle, which may compromise primary stability because of greater bone tissue damage despite faster insertion. The question of placement speed warrants further consideration. Indeed, another advantage of double-threaded implants is placement speed. The implantation speed...

Discussion : Effects of implant thread design on p...

Moreover, the IT and RT values of 12S were consistent with those of the standard implant (Straumann) measured in our previous study. Here, the RT value of each implant was lower compared with their respective IT values, consistent with other reports. The IT and RT values of 06S were highest, followed by 06D and 12S. In contrast, the differences between RT and IT values were highest for...

Discussion : Effects of implant thread design on p...

In the artificial bone adjacent to 06D, there were more voids compared with those associated with 06S or 12S, which accounts for the increase in torque. The highest numbers and larger sizes of debris particles were associated with 06D, followed by 0S and 12S, indicating the potential for greater tissue damage. These results likely explain the lower (50%) torque value of 06S compared with tho...

Discussion : Effects of implant thread design on p...

Discussion We show here that increasing thread length and reducing pitch can increase primary implant stability without changing the size of an implant. Compared with the standard single-threaded implant with a 1.2-mm pitch/lead (12S), torque values and ISQ were significantly increased by doubling the thread length by adding the second thread (06D) or by reducing pitch/lead and lead angle o...

Results : Effects of implant thread design on prim...

Results The IT, RT, and ISQ values revealed significant differences among the implants (Table 2). The IT and RT values of 12S were not significantly different compared with published data (IT, 13.13 ± 1.763 N cm; RT, 12.37 ± 1.746 N cm) (Student t test, df = 9, t = 2.91, p < .017). Compared with 12S, the IT and RT values of 06D and 06S were significantly different (147% and 150%, a...

Methods : Effects of implant thread design on prim...

Methods Implants Three types of grade-4 titanium cylindrical nonself-tapping implants (codes 12S, 06D, and 06S) were specially designed and manufactured (Suwa Co., Ltd., Fujiyoshida, Yamanashi, Japan) (Fig. 1 and Table 1). The code 12S single-threaded implant served as a reference. Codes 06D and 06S were designed to double the thread length compared to 12S. Code 06D was a double-threated impla...

Introduction : Effects of implant thread design on...

Introduction Secure primary stability is positively associated with successful long-term implant integration to ensure a successful clinical outcome. Initial implant stability is defined as biomechanical stability upon insertion, which is influenced by factors such as bone quantity and quality, geometry of the implant, surgical technique, and insertion torque (IT). New bone develops around the ...

Effects of implant thread design on primary stabil...

Effects of implant thread design on primary stability—a comparison between single- and double-threaded implants in an artificial bone model   Abstract Background Primary implant stability is essential for osseointegration. To increase stability without changing the implant size, the thread length must be extended by reducing pitch, using a double-threaded implant, or reducing pitch/lead a...

Figure 6. BIC percentage measured with ImageJ anal...

  Figure 6. BIC percentage measured with ImageJ analysis software

Figure 5. Time arrow about the stages of the study

  Figure 5. Time arrow about the stages of the study

Figure 4. A 2-month period was allowed for plaque ...

  Figure 4. A 2-month period was allowed for plaque retention and peri-implantitis

Figure 3. Silk ligatures placed in a submarginal p...

Figure 3. Silk ligatures placed in a submarginal position around the implants

Figure 2. Edentulous posterior mandible of the dog...

Figure 2. Edentulous posterior mandible of the dog at 3 months after tooth extraction  

Figure 1. Flowchart of the research design employe...

  Figure 1. Flowchart of the research design employed in the study. *Three dogs were used in each group 1 and 2. Three implants were inserted right side of the mandibles. After peri-implantitis period, extracted implants were inserted into the left side of the mandibles. **Two dogs were used in each group 3 and 4. Six failed implants from human inserted into the one dog’s mandible bilaterall...

Table 3 Inter- and intra-group ISQ analysis and me...

Table 3 Inter- and intra-group ISQ analysis and measurements on day of surgery and at 3-month follow-up     Mean ± SDISQ day 0 Mean ± SDISQ at 3 month p Group 1 69.33 ± 8.48 77.77 ± 1.78 .019 Group 2 68.88 ± 5.90 79.44 ± 2.55 .001* Group 3 71.77 ± 5.71 75.11 ± 5.84 .366 Group 4 70.44 ± 5.15 79.12 ± 4...

Table 2 Comparison of BIC percentages of 3 mm cres...

Table 2 Comparison of BIC percentages of 3 mm crestal area of the implants at 3-month follow-up Group 1[Mean ± SD] Group 2[Mean ± SD] Group3[Mean ± SD] Group 4[Mean ± SD] p 77.67 ± 5.03 75.28 ± 10.65 71.86 ± 8.34 80.63 ± 5.58 .144*

Table 1 Comparison of BIC percentages of over the ...

Group 1[Mean ± SD] Group 2[Mean ± SD] Group3[Mean ± SD] Group 4[Mean± SD] p 83.39 ± 6.37 79.93 ± 11.83 75.45 ± 9.09 80.53 ± 5.22 290*

Discussion : Reusing dental implants (3)

Levin et al. conducted a similar study and investigated the success rate of retrieved dental implants that were re-implanted into dogs. The infected implants were re-implanted into dog jaws without any chemical or mechanical cleaning and the authors reported that there was no difference in terms of BIC percentage between the infected/reinserted and new dental implants after a...

Discussion : Reusing dental implants (2)

Levin et al. conducted a similar study and investigated the success rate of retrieved dental implants that were re-implanted into dogs. The infected implants were re-implanted into dog jaws without any chemical or mechanical cleaning and the authors reported that there was no difference in terms of BIC percentage between the infected/reinserted and new dental implants after an appropriate he...

Discussion : Reusing dental implants (1)

Discussion Approximately two million new dental implants are inserted per year around the world and tens of millions of implants are still in use. Moreover, it is estimated that approximately 200,000–250,000 implants are removed every year. Peri-implantitis is the major cause of the implant retrieval and also the most common complication caused by implant surgery. Mombelli et al. reported...

Results : Reusing dental implants

Results The experimental period and the laboratory workup of the study were unremarkable. Surgical operations were uneventful and the post-operative healing periods were completed with no complications. Histologic analysis and the ISQ values indicated that osseointegration was achieved in all the implants. Histomorphometric analysis Histomorphometric analysis demonstrated that adequate bone f...

Methods : Reusing dental implants (4)

Removal and preparation of the implant-bone specimens The implants with a neighboring bone were removed en bloc, and the adhesive soft tissues were dissected to investigate the healing status and the bone-implant contact (BIC) percentage. The specimens were fixed in 10% neutral buffered formalin for 48 h and dehydrated in subsequent concentrations of 70–99.9% ethanol. After dehydration, the sp...

Methods : Reusing dental implants (3)

Subsequently, the implant surfaces were rinsed with sterile saline solution and then all the implants were inserted in the contralateral side of the mandible of the same dog. After a 3-month osseointegration period, the animals were sacrificed with a high dose of pentobarbital (i.v.). In group 2, the same procedures were applied as in group 1. However, unlike the implants in group 1, the implants...

Methods : Reusing dental implants (2)

Infiltration anesthesia with 2% articaine (Ultracaine DS, Sanofi Aventis Drugs, Istanbul, Turkey) was applied to the premolar area for hemostasis and for post-operative pain control. A full-thickness vestibular flap was elevated gently, and surgical tooth extraction was performed using surgical burs with straight elevators. Surgical wounds were closed with 3/0 vicryl sutures and streptomycin 0.5 g...

Methods : Reusing dental implants (1)

Methods Research design This in vivo study had a comparative, randomized, prospective research design, and each group consisted of 10 male beagle dogs that were veterinarian-controlled, healthy, and of similar weight. Animal Research Reporting in Vivo Experiment (ARRIVE) guidelines were used, and surgical procedure was approved by the Local Animal Experiments Ethical Committee of Erciyes Unive...

Background : Reusing dental implants

Background Branemark et al. conducted the first experimental trial with titanium dental implants and created a new vision by defining the term “osseointegration” in the 1960s. Despite the advances in implant technology and protocols and the accumulating evidence in the literature, implant failure/loss may still occur due to several reasons. On the other hand, although dental implant therapy...

Reusing dental implants

Reusing dental implants: an experimental study for detecting the success rates of re-osseointegration   Abstract Background The aim of this study was to histomorphometrically compare the implant-host integration between retrieved implants and new implants. Methods Jaws in 10 male beagle dogs were divided into four groups, and 36 dental implants were inserted into the jaws. In groups 1 and...

Table 4 Implant survival in autogenous bone grafts...

  RDX No RDX Author Year of publication No. of implants placed into autogenous bone grafts with RDX (and failures) Overall implant survival of implants placed into autogenous bone grafts with RDX No. of patients who had implants placed into autogenous bone grafts with RDX (and failures) Patient based implant survival of implant placed into autogenous bone grafts with RDX No. of...

Table 3 Implant survival in autogenous bone grafts...

  Non-vascularised bone graft Vascularised bone graft Author Year of publication No. of patients who had implants placed into non-vascularised autogenous bone grafts (and failures) Overall patient implant survival in non-vascularised autogenous bone grafts No. of implants placed into non-vascularised autogenous bone grafts (and failures) Overall implant survival in non-vasculari...

Table 2 Summary of implant survival and implant su...

  Implant survival Implant success Author Year of publication Donor site of autogenous bone graft Radiotherapy/chemotherapy to bone graft site Complications No. of patients who had implants placed into autogenous bone grafts (and failures) Overall patient implant survival in autogenous bone grafts No. of implants placed into autogenous bone grafts (and failures) Overall i...

Table 1 Study characteristics and MINORS scores

Author Year of publication Study design Outcome measure Criteria—survival Criteria—success Quality assessment using the MINORS assessment tool Head and neck cancer diagnosis Patients age range Follow-up period Implant site Implant system Implant placement protocol Prosthodontic rehabilitation Studies with an average follow-up of 3 years or greater Watzinger et...

Figure 1. Flow chart of study selection procedure

Figure 1. Flow chart of study selection procedure

References : Survival of dental implants placed

References Schoen PJ, Reintsema H, Raghoebar GM, Vissink A, Roodenburg JLN. The use of implant retained mandibular prostheses in the oral rehabilitation of head and neck cancer patients. A review and rationale for treatment planning. Oral Oncol. 2004;40:862–71. Müller F, Schädler M, Wahlmann U, Newton JP. The use of implant-supported prostheses in the functional and psychosocial rehabi...

Conclusion : Survival of dental implants placed

Conclusion Within the limitations of the current review, it can be concluded that implant survival in autogenous bone grafts in H&N oncology patients appears to be promising with implant survival being reported at over 80% in 16 of the 20 studies included with 11 of these reporting implant survival of over 90% in follow-up ranging from 3 months [28] to 15 years [5]. However, there i...

Discussion : Survival of dental implants placed (3...

A clear deficiency of many of the studies was the imprecise and inconsistent definitions of implant survival or implant success, as detailed in Table 1. In addition, in a number of studies, the terminology ‘implant success’ and ‘implant survival’ were used interchangeably within the narrative making comparison of the studies challenging and rendering statistical analysis of the surv...

Discussion : Survival of dental implants placed (2...

The implant placement protocol with regard to primary (immediate) or secondary (delayed) implant placement was also reviewed, and there is limited evidence from Fenlon et al. that implant failure is significantly worse in immediately placed implants in comparison with a delayed approach in free vascularized grafts. Implant success was shown to be lower than implant survival and was related ...

Discussion : Survival of dental implants placed (1...

Discussion Summary of evidence Dental implants are now perceived to be a vital part of the clinician’s armamentarium in the provision of oral and dental rehabilitation for patients with acquired deformity following management of their H&N cancer, and therefore, this systematic review is relevant to clinicians and stakeholders involved in the treatment and management of H&N cancer patient...

Results : Survival of dental implants placed (8)

Six of these studies (Schultes et al., Wang et al., Zou et al., Chiapasco et al., Chiapasco et al., Wu et al.) reported some of this lack of success to the peri-implant soft tissue which was most frequently the soft tissue component of a combined bone and soft tissue free flap (most commonly the external skin). Complications A variety of implant-based complications were documented. Complicatio...

Results : Survival of dental implants placed (7)

Implant survival and Peri-implant soft tissue Only one study (Linsen et al. ) reported on the effect of the peri-implant soft tissue and implant survival of implants placed into autogenous bone grafts. Linsen et al. reported a higher implant failure of implants placed into bone and soft tissue grafts in comparison to implants placed into a bone grafts with residual soft tissues. This difference...

Results : Survival of dental implants placed (6)

However, in two studies (Teoh et al., Burgess et al.), no statistical significance was found despite higher implant failure. Primary and secondary implant placement and implant survival Six studies clearly reported the use of both primary and secondary implant placement within their study (Fenlon et al., Ch’ng et al., Zou et al., Burgess et al., Watzinger et al., Wu et al.); however, only on...

Results : Survival of dental implants placed (5)

Two studies (Fenlon et al., Burgess et al. ) reported no significant effect on implant survival in varying graft donor sites; however, three studies (Hessling et al., Shaw et al., Chiapasco et al.) reported varying implant survival rates within different autogenous bone grafts but only one study (Hessling et al.) reported that implant loss was significant with this being for implants placed into...

Results : Survival of dental implants placed (4)

Autogenous bone graft type and implant survival Seventeen studies reported on the specific bone graft type (non-vascularised or vascularised) into which the implants were placed. In the remaining three studies (Buddula et al., Fierz et al., Yerit et al.), this distinction was not possible. Of these 17 studies, 8 studies reported on implant survival in non-vascularised bone grafts and 14 studie...

Results : Survival of dental implants placed (3)

The surgical and loading implant protocols were reported in 17 studies with no description given in 3 studies (Barrowman et al., Fierz et al., Hessling et al.). The implant placement protocols were diverse with variables including the use of surgical templates/guides, primary and/or secondary implant placement following autogenous bone grafting, and immediate and/or delayed implant loading; howe...

Results : Survival of dental implants placed (2)

These 20 studies were published over a range of 21 years (1996 to 2017) and provide cumulative data on 1905 implants placed into autogenous bone grafts in H&N cancer patients with both benign and malignant tumours being reported. The exact patient number for this intervention within some of the studies was unclear as a result of the studies reporting on implant rather than patient number or ther...

Results : Survival of dental implants placed (1)

Results Study selection Searches of EMBASE, the Cochrane Central Register of Controlled Trials, Science Direct and MEDLINE generated 619 articles. After duplicate articles were removed, 566 unique articles were remaining. After the review of the titles and abstracts, 151 articles were accepted for further consideration, and 415 were rejected. After the full text was attained and reviewed for t...

Methods : Survival of dental implants placed (3)

Data items Data was collected for implant survival, implant success, implant failure, implant complications, surgical implant placement protocol, implant system used, clinical follow-up, how the author defined success/survival, the type of autogenous bone graft, implant site, the prosthodontic rehabilitation and type of cancer, and the use of radiotherapy were documented where possible. Risk of ...

Methods : Survival of dental implants placed (2)

Information sources Four electronic databases were used to systematically search the available literature: (1) The National Library of Medicine (MEDLINE via PubMed), (2) EMBASE, (3) Cochrane Central Register of Controlled Trials and (4) Science Direct. The searches were limited to studies involving human subjects and publication dates from January 1980 to August 2017 that satisfied the inclusion ...

Methods : Survival of dental implants placed (1)

Methods Protocol The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) for describing and summarising the results of our review was used. A quality assessment of all selected full-text articles was performed using the Methodological Index for Non-Randomized Studies (MINORS) assessment tool to assess the risk of bias of the included studies. The MINORS scoring list co...

Introduction : Survival of dental implants placed

Introduction Rationale The use of implants to retain prostheses as part of oral and dental rehabilitation of head and neck (H&N) cancer patients is becoming an increasingly common treatment approach. A number of benefits advocating implant anchorage over conventionally secured prostheses have been proposed but importantly include a significant improvement in the reported quality of life (QoL) of...

Survival of dental implants placed in autogenous b...

Survival of dental implants placed in autogenous bone grafts and bone flaps in head and neck oncology patients: a systematic review   Abstract Using implants to retain prostheses as part of the oral rehabilitation of head and neck cancer patients is an increasingly common treatment modality, particularly in transported bone which is used to reconstruct defects following oncological surgical ...

Table 1 Implant characteristics—insertion region...

Patient Implant region(FDI) Implant parameters Dimensions of implantDiameter [mm]/length [mm] Explantation[Days after placement] 1 3637 First placementStraumannRN SLactive®(TiZr) First placementØ: 4.1; L: 10Ø: 4.1; L: 8 3   3637 Second placementStraumannTissue level(TiZr) Second placementØ :4.1, L: 8Ø :4.1, L: 8 3   36 Third placementConelog ScrewLine(...

Figure 2. a Patient 2. Postoperative orthopantomo...

  Figure 2. a Patient 2. Postoperative orthopantomogram one day after implant placement. b Patient 2. Postoperative orthopantomogram after second Implant placement

Figure 1. a Patient 1. Post grafting orthopantomo...

  Figure 1. a Patient 1. Post grafting orthopantomogram. The bone block was secured with a single microscrew. b Patient 1. The radiograph demonstrates veritable inserted Straumann bone level implants after the first implant placement (1 day after implant placement). A peri-implant osteolysis is not visible. c Patient 1. Postoperative orthopantomogram (1 day after implant placement) afte...

References : Vitamin D deficiency in early implant...

References Esposito M, Thomsen P, Ericson LE, Lekholm U. Histopathologic observations on early oral implant failures. Int J Oral Maxillofac Implants. 1999;14:798–810. Olmedo-Gaya MV, Manzano-Moreno FJ, Cañaveral-Cavero E, de Dios Luna-Del Castillo J, Vallecillo-Capilla M. Risk factors associated with early implant failure: a 5-year retrospective clinical study. J Prosthet Dent. 2016;115...

Discussion : Vitamin D deficiency in early implant...

However, a synergistic effect with other factors is conceivable. Some authors stated that implant osseointegration is not simply a wound healing phenomenon but rather complex foreign body reaction with activation of the immune system. Titanium and metal particle release is discussed as cause for implant failure as well as implant dentistry. It is assumed that metal particles influence the ma...

Discussion : Vitamin D deficiency in early implant...

However, a present human study cannot confirm an effect due to vitamin D supplementation on bone formation or graft resorption after maxillary sinus augmentation. Satue et al. found a positive influence of 7-dehydrocholesterol (7-DHC), the precursor of vitamin D, coated implants on osteoblast differentiation in vitro. But whether vitamin D-coated dental implants have an effect of osseo...

Discussion : Vitamin D deficiency in early implant...

Discussion This article demonstrated that implant placement was successful after vitamin D supplementation in patients with vitamin D deficiency and early failed implants. None of the patients showed systemic disease or did take regular medication, alcohol, nicotine, or drugs. The patients were not immunosuppressed, irradiated, or received chemotherapy. All implants were inserted with the s...

Case presentation : Vitamin D deficiency in early ...

After vitamin D supplementation and a healing period of 6 months, a third surgical intervention was planned and one implant (Conelog ScrewLine) was inserted in region 36 (see Table 1 and Fig. 1d). During implant placement, the former explantation site appeared clinically fully re-ossified. The patient received an intraoperative intravenous single-dose antibiotic therapy with Isocillin 1.2 mega. At...

Case presentation : Vitamin D deficiency in early ...

  Patient The medical history of this 48-year-old male patient showed a high blood pressure; otherwise, the patient was healthy. A successfully completed periodontal therapy was done before implant therapy. The patient demonstrated stable marginal bone levels. Autologous retromolar bone grafting using local anesthesia was performed in the left mandible (see Fig. 1a). This patient received a pos...

Case presentation : Vitamin D deficiency in early ...

Case presentation Patients and surgical procedure Patients treated consecutively in one center (Department of Oral- and Craniomaxillofacial Surgery, University Medical Center Freiburg). None of the patients showed systemic disease. Both patients did not take regular medication and were negative for alcohol, nicotine, and drug use. Bothe male patients (48 and 51 years of age) were not immunosu...

Background : Vitamin D deficiency in early implant...

Background Long-term stable osseointegrated implants are the primary goal in dental implantology. Although dental implants have proven clinical reliable in the long term, the failure of implants at a very early stage of osseointegration has been described. The pursuit to identify the mechanisms leading to early implant failure is ongoing to date and include the following: tobacco usage, diabete...

Vitamin D deficiency in early implant failure: two...

Abstract An association between vitamin D deficiency and early dental implant failure is not properly verified, but its role in osteoimmunology is discussed. This article illustrates two case reports with vitamin D deficiency and early implant failure. Prior to implant placement, the first patient received crestal bone grafting with autologous material. Both patients received dental implants fr...

Figure 4. Kaplan-Meier implant survival curves for...

Figure 4. Kaplan-Meier implant survival curves for bone and bone substitutes

Figure 3. Kaplan-Meier survival curves for membran...

  Figure 3. Kaplan-Meier survival curves for membrane types

Figure 2. Kaplan-Meier implant survival curves for...

  Figure 2. Kaplan-Meier implant survival curves for augmentation procedures

Figure 1. Kaplan-Meier survival curves for implant...

Figure 1. a Kaplan-Meier survival curves for implants with or without augmentation. Dashed line 95% confidence interval. b Kaplan-Meier survival curves for single crown implants overall and with or without augmentation. Dashed line 95% confidence interval

Table 5 Implants lost and in function up to 20.2 y...

Table 5 Implants lost and in function up to 20.2 years after implant insertion using different graft materials Graft material Implants (n) Min/max observation time (years) Lost implants % (n) Absolute survival rate % p value No graft material 4609 0.0/20.2 5.51 (254) 94.49   Geistlich Bio-Oss 2939 0.0/15.6 2.76 (81) 97.24 0.0004 Autogenous bone particles ...

Table 3 Explantations of implants inserted using d...

Table 3 Explantations of implants inserted using different augmentation procedures up to 20.2 years after implantation   Augmentation procedure Implants(n) Lost implants % (n) Absolute survival rate % p value No augmentation 4242 5.72 (243) 94.28   Lateral augmentation 3210 4.02 (129) 95.98 0.0010 External sinus lift one-step 1101 4.09 (45) 95.91 0.032...

Table 2 Implant loss in augmented and non-augmente...

Table 2 Implant loss in augmented and non-augmented sites up to 20.2 years after implant insertion Augmentation Implants (n) Lost implants % (n) Early implant loss % (n) Late implant loss % (n) Absolute survival rate % No augmentation 4242 5.73 (243) 0.38 (16) 5.35 (227) 94.27 With augmentation 5916 3.67 (217) 0.32 (19) 3.35 (198) 96.33 Total 10158 4.53 ...

Table 1 Distribution of implants according to the ...

Table 1 Distribution of implants according to the period of observation Year Number of implants Relative number of implants (%)

References : Retrospective analysis of 10,000 impl...

References Buser D, Martin W, Belser UC. Optimizing esthetics for implant restorations in the anterior maxilla: anatomic and surgical considerations. Int J Oral Maxillofac Implants. 2004;19(Suppl):43–61. Nkenke E, Neukam FW. Autogenous bone harvesting and grafting in advanced jaw resorption: morbidity, resorption and implant survival. Eur J Oral Implantol. 2014;7 Suppl 2:S203–17. von ...

Discussion : Retrospective analysis of 10,000 impl...

In addition, Buch et al. compared the different criteria proposed for implant success with regard to their clinical value. The authors demonstrated that the proposed criteria led to very different success rates 6 years after implant insertion (75–89%) and did not allow reliable comparison of the results with each other. Thus, during control visits in our practices, only prosthetic complica...

Discussion : Retrospective analysis of 10,000 impl...

The most often used graft material in our evaluation was Geistlich Bio-Oss (53.0%) followed by autogenous bone (32.5%). When compared to no graft, the use of both grafts resulted in significantly higher implant survival rates. In various studies, the bone substitute was found to promote bone regeneration and to allow for long-term stability of the augmented volume. A recent meta-analysis com...

Discussion : Retrospective analysis of 10,000 impl...

However, there are also a few clinical studies in which reduced survival rates for implants inserted in grafted areas were found. Differences in numbers of implants analysed, surgical techniques, indications and/or graft materials may account for these inconsistent results and further studies might be needed. In the retrospective analysis shown here, the comparison of different augmentation...

Discussion : Retrospective analysis of 10,000 impl...

Discussion The retrospective analysis presented here evaluates implants inserted in three different private practices with or without augmentation procedures. Treatments were performed according to the standard protocols applied in the private practices. More than 10,000 implants were inserted in various indications and were followed up to 20.2 years from the day of implant insertion. The o...

Results : Retrospective analysis of 10,000 implant...

When looking into the Kaplan-Meier implant survival curves of the augmentation procedures using the log-rank test, the highest implant survival was found for bone condensing followed by lateral augmentation, internal sinus lift, transplantation of bone blocks, bone splitting/spreading, titanium mesh, external sinus lift (one- and two-step) and finally, no augmentation. This sequence was statistica...

Results : Retrospective analysis of 10,000 implant...

Results Of the 10,158 implants, 58.2% (5916 implants) were inserted using an augmentation procedure. The minimal observation period until the last control visit or until explantation was 0 days (day of implantation); the maximum period was 20.2 years. Distribution of analysed implants according to the period of observation is shown in Table 1. A total of 4.53% (460 implants) of all implants...

Statistical evaluation : Retrospective analysis of...

The membranes applied included the native collagen membrane Geistlich Bio-Gide (Geistlich Pharma AG, Wolhusen, Switzerland) either alone or combined with one of the following membranes: Vicryl (Johnson & Johnson Medical GmbH, Norderstedt, Germany), Biovin Membran (OT Medical, Bremen, Germany), Parasorb Vlies (Resorba, Nuremberg, Germany), Gore-Tex Resolut (W.L. Gore & Associates, F...

Methods : Retrospective analysis of 10,000 implant...

The membranes applied included the native collagen membrane Geistlich Bio-Gide (Geistlich Pharma AG, Wolhusen, Switzerland) either alone or combined with one of the following membranes: Vicryl (Johnson & Johnson Medical GmbH, Norderstedt, Germany), Biovin Membran (OT Medical, Bremen, Germany), Parasorb Vlies (Resorba, Nuremberg, Germany), Gore-Tex Resolut (W.L. Gore & Associates, Flagstaff, USA), ...

Methods : Retrospective analysis of 10,000 implant...

Methods The retrospective analysis evaluates patients who underwent implant therapy with or without accompanying augmentation procedures between August 1991 and December 2011 in three private practices. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines were followed. To investigate the effect of the different techniques applied on implant survival without ...

Background : Retrospective analysis of 10,000 impl...

Background Replacing missing teeth with dental implants is a routine treatment in many dental practices. In order to achieve adequate functional and aesthetic results, an optimal three-dimensional implant position has to be assured. Various materials are available to build up missing bone. While autogenous bone is usually regarded to be the gold standard, harvesting may be associated with morbi...

Retrospective analysis of 10,000 implants

Retrospective analysis of 10,000 implants from insertion up to 20 years—analysis of implantations using augmentative procedures Abstract Background A sufficient amount of bone is essential to ensure long-term stability of dental implants. To support the bone regeneration process, different techniques and materials are available. It has been questioned whether these techniques and materials...

Table 3 Mean value and standard deviation for the ...

Item Mean ± SD pre-operative Mean ± SD post-operative Mean ± SD in the last time Have you felt pain in your mouth? 0.9 ± 1.1 1.2 ± 1.0 0.3 ± 0.6 Have you had difficulties with your mouth opening? 0.2 ± 0.6 0.5 ± 0.9 0.1 ± 1.0 Have you had painful gums? 0.9 ± 1.0 1.0 ± 1.1 0.5 ± 0.8 Have you had a ...

Table 2 Mean value and standard deviation

Item Mean ± SD before sinus lift Mean ± SD after sinus lift p value Have you felt tense because of problems with your teeth, mouth or dentures? 1.8 ± 1.1 0.8 ± 1.0

Table 1 Mean value and standard deviation

Item Mean ± SD before sinus lift Mean ± SD after sinus lift p value Have you had difficulty chewing any foods? 1.6 ± 1.2 0.4 ± 0.7

Figure 5. Total score for physical and psychologic...

  Figure 5. Total score for physical and psychological disabilities before (gray) and after (hatched) sinus augmentation according to indications

Figure 4. Total score for functional limitations b...

  Figure 4. Total score for functional limitations before (gray) and after (hatched) sinus augmentation according to indications

Figure 3. Total score for complaints

  Figure 3. Total score for complaints due to surgical procedure pre-operative, post-operative, and recently

Figure 2. Cumulative survival rate

  Figure 2. Cumulative survival rate according to Kaplan–Meier and sinus augmentation procedure  

Figure 1. Flow chart of patients included in the s...

Figure 1. Flow chart of patients included in the study Figure 1. Flow chart of patients included in the study

References : Impact of maxillary sinus augmentatio...

References Al-Nawas B, Schiegnitz E. Augmentation procedures using bone substitute materials or autogenous bone—a systematic review and meta-analysis. Eur J Oral Implantol. 2014 Summer;7 Suppl 2:S219-34. Derks J, Hakansson J, Wennstrom JL, Tomasi C, Larsson M, Berglundh T. Effectiveness of implant therapy analyzed in a Swedish population: early and late implant loss. J Dent Res. 2015;94(...

Discussion : Impact of maxillary sinus augmentatio...

  The authors concluded that in clinical decision-making regarding donor site for bone graft harvesting, patients and clinicians should consider expected decrease in HRQoL if deciding to use extra-oral donor sites. Therefore, the authors recommended to prefer intra-oral donor sites whenever possible. In a recent study of Nickenig et al., OHIP-G 21 was evaluated in 8689 patients with variou...

Discussion : Impact of maxillary sinus augmentatio...

In this prospective study, health-related quality of life questionnaire was given to 76 patients evaluating patient perception of recovery in the four areas pain, oral function, general activity, and other symptoms. The results showed that average and maximal pain peaked on post-operative day 1 and improved on post-operative days 4 and 5. Difficulty in mouth opening was greatest on pos...

Discussion : Impact of maxillary sinus augmentatio...

Discussion The clinical and radiological outcomes of sinus augmentation procedures have been published in several studies. However, little data on the physical and psychological impact of this procedure on the patient is available yet. The present study evaluated pre-operative and post-treatment OHRQoL self-assessment scores of patients treated with dental implants after sinus augmentation ...

Results : Impact of maxillary sinus augmentation (...

In the subcategory physical and psychological disabilities, all questions had significant better values after the sinus lift (p 

Results : Impact of maxillary sinus augmentation (...

Results Survival analysis After an average time in situ of 41.2 ± 27 months (3.4 years; range 0–96 months), 40 of the 863 implants were lost. These results indicated an in situ rate of 95.4%. One-year and five-year survival rate according to Kaplan–Meier were 95.4 and 94.4%. In patients receiving an external sinus lift an in situ rate of 95.1% and in patients with an internal sinus...

Methods : Impact of maxillary sinus augmentation o...

Methods Study design and subjects This retrospective study addresses the oral health-related quality of life after maxillary sinus augmentation. Therefore, all patients that received an implantation after maxillary sinus augmentation in the Department of Oral and Maxillofacial Surgery of the University Medical Centre Mainz, Germany, between July 2002 and December 2007 were included in this stu...

Background : Impact of maxillary sinus augmentatio...

Background Rehabilitation of completely and partial edentulous patients with dental implants has proved to be a safe and predictable procedure. However, reduced bone height and the proximity of the maxillary sinus are challenging limitations for dental implant placement in the posterior maxilla. Besides the use of short and tilted implants, one of the most frequently used surgical techniques fo...

Impact of maxillary sinus augmentation on oral hea...

Abstract Background The aim of this study was to measure the oral health-related quality of life (OHRQoL) after maxillary sinus augmentation to determine the physical and psychological impact of this procedure for the patient. Methods Three hundred sixteen patients treated with an external or internal maxillary sinus augmentation and a total of 863 implants in the Department of Oral and Maxi...

Figure 5. Osteoblasts with an orientation tendency...

  Figure 5. Osteoblasts with an orientation tendency after 24 h of rotation (phallacidin fluorescence staining). On the left side with 200× and on the right side with 400× magnification. The yellow arrows show the orientation of the cells. The red arched arrow within the coloured circle shows the direction of rotation. The dashed white line oriented to the right stands for the r...

Figure 4. Randomly orientated osteoblasts without ...

  Figure 4. Randomly orientated osteoblasts without influence of rotation (phallacidin fluorescence staining). On the left side with 200× and on the right side with 400× magnification. The white X on the coloured circle marks the location upon the plate where the osteoblasts were located. The red X marks the centre of the plate

Figure 3. Diagram for visualisation of the calcula...

  Figure 3. Diagram for visualisation of the calculation of shear stress rates taking into account the centrifugal force and the glass plates’ dimensions. For example, at a distance of 25 mm from the centre of the upper plate, the shear forces’ value is 8.33 dyn/cm2, together with an additional centrifugal force that has a value of 0.55 dyn/cm2

Figure 2. Side view of a computerized simulation

  Figure 2. Side view of a computerized simulation, showing the flow chambers’ lower compartment and the flow profile in between the two plates; shearing gap and bottom plate are shown on the left side; rotation speed = 200 rpm; colour code bar (left edge) showing shear force values [Pa] [1 Pa = 10 dyn/cm2]; flow direction presented by arrows

Figure 1. Three-dimensional illustration and photo...

Figure 1. Three-dimensional illustration (a–e) and photography (f) of the experimental setup with the components marked numerical. a 1 Lower petri dish (s’ bottom serving as the lower plate); 2 Rotating glass panel [60 mm diameter (cell bearing)]; 3 Titanium axis. b 4 Liquid medium (red). c 5 Reversed upper petri dish. d 6 Gearwheel with set screw. e 7 Closing; 8 Electronic motor device and ...

References : Cellular fluid shear stress on implan...

References Ehrlich PJ, Lanyon LE. Mechanical strain and bone cell function: a review. Osteoporos Int. 2002;13(9):688–700. Vaughan TJ, Haugh MG, Mcnamara LM. A fluid-structure interaction model to characterize bone cell stimulation in parallel-plate flow chamber systems. J R Soc Interface. 2013;10(81):20120900. Weinbaum S, Cowin SC, Zeng Y. A model for the excitation of osteocytes by mec...

Discussion : Cellular fluid shear stress on implan...

Besides, in the model reported in this study, microscopic examinations are possible after completing the experiment only. Nevertheless, an advantage of the new flow chamber is the possibility of testing different cell colonies simultaneously in one single experiment by placing cells in different radial locations on the spinning disc. Due to the current flow gradient from the centre to the pe...

Discussion : Cellular fluid shear stress on implan...

Due to the fact that constant flows were generated within the parallel flow chamber only, the situations of in vitro experiments differ from in vivo setting where dynamic flow profiles are particular. As the constant laminar flow profile is not physiological in bones, vessels and other tissues, the informative value of the experimental setting is limited but it could be used for various cell...

Discussion : Cellular fluid shear stress on implan...

Further on, the simulations indicated that the flow profile in between the two plates was not influenced by peripheral turbulences alongside the peripheral regions. To verify a cellular realignment towards the shear direction, cells were microscopically examined prior and after exposure to shear forces for 24 h upon a spinning disc at a speed level of 200 rpm. Even if not sufficiently ...

Discussion : Cellular fluid shear stress on implan...

Discussion The aim of this study was to establish a new FSS model that is easy to use as well as simple to assemble in order to create reproducible fluid shear forces on cells close to implant material surfaces. Todays’ commonly used commercial flow devices differ in geometry and function, which makes comparisons between experiments difficult. The benefits of this novel testing device are...

Results : Cellular fluid shear stress on implant s...

Regarding the upper compartment, peripheral turbulent flow along the outer edges was similar to the fluid movements within the area in between the plates. At the top, the turbulent flow directed from the centre to the periphery whereas the turbulences at the bottom were orientated in reverse to that. Moreover, the effect of the shear forces on the osteoblast cells was also influenced by the centri...

Results : Cellular fluid shear stress on implant s...

Results Our analysis was focused on two main aspects: Simulation of the fluid flow characteristics as well as quantification of the arising shear forces at the plate/plate flow chamber with reliable reproducibility Assessment of the impact of fluid shear stress on osteoblast cells in terms of altered cell morphology and intracellular structural changes Evaluation of the f...

Methods : Cellular fluid shear stress on implant s...

  Test procedure The experimental process involved three steps. First, a count of n = 50.000 commercially available osteoblasts (PromoCell, Heidelberg, Germany) per millilitre of culture medium were cultured on the bottom of the cell-bearing surface (glass panel). Therefore, cells were seeded in a culture medium (cf. Appendix 2 for a detailed composition) at 37 °C. Prior to the test proce...

Methods : Cellular fluid shear stress on implant s...

  Analytical formula for evaluating the flow characteristics Frequently used flow chambers are characterised by an internal fluid flow along a stationary cell-bearing surface, whereas the osteoblast test cells of this newly developed model are circulating within a resting culture medium. For constant and fully developed laminar flow between the two parallel plates, the magnitude of the wall sh...

Methods : Cellular fluid shear stress on implant s...

Methods Experimental setup A three-dimensional illustration and photography of the plate/plate flow chamber model is shown in Fig. 1. A detailed list of used parts can be found in Appendix 1. The circulation within the flow chamber was generated by an externally attached electric motor, which rotates up to 500 rounds per minute (rpm). A commercial grade 4 pure medical titanium gear shaft (len...

Cellular fluid shear stress on implant surfaces

Abstract Background Mechanostimuli of different cells can affect a wide array of cellular and inter-cellular biological processes responsible for dental implant healing. The purpose of this in vitro study was to establish a new test model to create a reproducible flow-induced fluid shear stress (FSS) of osteoblast cells on implant surfaces. Methods As FSS effects on osteoblasts are detectabl...

Reference : Dental implants in patients treated wi...

Abbreviations BP: bisphosphonate BP-ONJ: bisphosphonate-associated osteonecrosis of the jaws CTX: C-terminal telopeptide of the type I collagen PICO: patients intervention control outcome PRISMA-P: preferred reporting items for systematic reviews and meta-analyses protocols QoL: quality of life ST: search term TMJ: temporomandibular joint ...

Discussion : Dental implants in patients treated w...

Next to this, the patients need to be compliant with an appropriate motivation for oral hygiene and the necessary skills to transfer this. Infectious foci should be treated before implant therapy to further reduce the risk of osteonecrosis development. The surgical sites should be followed up clinically (persisting sharp bone edges without any tendency to remodel) and radiologically (e...

Discussion : Dental implants in patients treated w...

Although there are only very few cases in the literature with augmentation of bone/sinus lift, these procedures are linked to a functioning vascular recipient site with working osteoclastic resorption and osteoblastic bone formation, and this is compromised in patients with antiresorptive therapy. Due to the denudation of the bone at the recipient site the vascular situation might be e...

Discussion : Dental implants in patients treated w...

Discussion Even latest guidelines and statements dealing with medication associated osteonecrosis of the jaws such as the American, Scottish, Swiss or German do not address implant therapy in these patients in detail. Due to this lack of data a systematic literature review was performed to fill this gap. Unfortunately the literature dealing with this topic is very sparse and consists mainl...

Results : Dental implants in patients treated with...

Nibbe analyzed 128 patients with IV BP or denosumab separated into 3 groups. In the first group 5 out of 60 patients with no denture had an osteonecrosis (8%), in the 2nd group 5 out of 34 patients with a fixed partial denture had an osteonecrosis 15%, and in the 3rd group 11 out of 34 patients with a removable denture had an osteonecrosis (32%). Kyrgidis determined that dentures increase the ris...

Results : Dental implants in patients treated with...

Results Out of 606 articles 556 articles were excluded because they were either duplicates, case reports, narrative reviews, case series with less than 5 cases or were not associated with the topic at all (Table 1 and Fig. 1). Some of the articles analyzed more than one outcome and are referred to several times. Since the available literature is very inhomogeneous with a low level of evidence a...

Introduction : Dental implants in patients treated...

Introduction Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is a well-known side effect in patients receiving bisphosphonates (BP) due to e.g. osteoporosis, multiple myeloma or malignant diseases with metastases to the bone; prevalences range between 0.1% for patients with primary osteoporosis to 1% in patients with secondary osteoporosis and up to about 20% for special high risk ...

Dental implants in patients treated with antiresor...

Dental implants in patients treated with antiresorptive medication – a systematic literature review Abstract Objective Bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) is triggered by inflammatory processes. Typical trigger factors are periodontal disease, denture pressure sores, and surgical interventions such as tooth extractions. Unfortunately there is only little data on how...

Table 2 Risk of bias of the included studies

Author Year Study type Selection bias (homogeneity and confounders) Performance bias (fidelity to protocol) Attrition bias (loss of participants) Detection bias (reliable measures) Reporting bias (selective reporting or conflict interests) Summary assessment risk of bias Alsaadi 2007 Retrospective H U U L L L Aguilar-Salvatierra 2015 Prospective H L L L L...

Table 1 List of the included studies and its main ...

Table 1 List of the included studies and its main characteristics   Author Year Study type Diabetes type Control Diabetes therapy Glycemic control [HbA1c %] Duration of diabetes (years) Number of patients Number of implants Duration of study (years) Implant survival [%] Conclusion Alsaadi 2007 Retrospective Type II Non-diabetes n.d. n.d. n.d. 2004 (overall) 6...

Figure 1. Selection process of the included litera...

Figure 1. Selection process of the included literature

References : Dental implants and diabetes mellitus...

References Moraschini V, Poubel LA, Ferreira VF, Barboza Edos S. Evaluation of survival and success rates of dental implants reported in longitudinal studies with a follow-up period of at least 10 years: a systematic review. Int J Oral Maxillofac Surg. 2015;44(3):377–88. Khader YS, Dauod AS, El-Qaderi SS, Alkafajei A, Batayha WQ. Periodontal status of diabetics compared with nondiabetics...

Conclusion : Dental implants and diabetes mellitus...

  Conclusions The literature included to this review is very heterogeneous concerning the investigated objects, methods, and conclusions. Diabetes is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. When looking at the complications and side effects resulting from diabetes, it is important to know which type of diabetes the pati...

Results : Dental implants and diabetes mellitus—...

While four studies conclude better implant survival and less peri-implant complications in the well-controlled group, the three others see no difference in implant success even in the poorly controlled patients. The study of Khandelwal treated exclusively patients with poor glycemic control (HbA1c 7.5–11.4 %) and had 98 % implant survival, after 4 months; therefore, he concluded that impla...

Results : Dental implants and diabetes mellitus—...

  Diabetes and bone augmentation We identified two prospective studies that evaluated “advanced” implant surgery covering sinus lift procedure and guided bone regeneration. The study of Erdogan consists of type II diabetics moderately and well-controlled (HbA1c 6–7.5 %) with a mean duration of disease of 7.5 years and a healthy control group. Augmentation of the maxilla was perform...

Results : Dental implants and diabetes mellitus—...

 The bleeding on probing is more often in the poorly controlled population, but the probing depth is not increased. Diabetes and implant survival Implant survival is an easily defined and measured endpoint for dental implant therapy. Nearly every study reports its implant survival rate. Our literature search identified 18 publications with these data. We divided them into two groups: the ...

Results : Dental implants and diabetes mellitus—...

The results in the prospective study of Gomez-Moreno show that elevated HbA1c causes more bone resorption after 3 years, but this effect is not significant. We identified two prospective studies investigating the influence of type II diabetes on osseointegration. They are published by the same author but are independent studies from different years. In both studies, the patients included...

Results : Dental implants and diabetes mellitus—...

Results Study selection There are no guidelines existing to the topic of dental implants and diabetes mellitus. A total of 327 potentially relevant titles and abstracts were found by the electronic search and additional evaluation of reference lists. During the first screening, 230 publications were excluded based on the title and keywords. Additionally, 24 titles were excluded based on abstract...

Materials & methods : Dental implants and diabetes...

Materials and methods The substructure of the systematic review is based on the PRISMA statement. The focused question according to the PICO schema is: “Do diabetic patients with dental implants have a higher complication rate in comparison to healthy controls?” Search strategies The systematic literature search was performed by an independent scientist (Burkhard Kunzendorf). The following ...

Review : Dental implants and diabetes mellitus—a...

Review Introduction Today, dental implants are one of the restorative methods to replace missing teeth. Improvements in implant design, surface characteristics, and surgical protocols made implants a secure and highly predictable procedure with a mean survival rate of 94.6 % and a mean success rate of 89.7 % after more than 10 years. Implant survival is initially dependent on successful osseoi...

Dental implants and diabetes mellitus—a systemat...

Abstract Dental implant surgery has developed to a widely used procedure for dental rehabilitation and is a secure and predictable procedure. Local and systemic risk factors can result in higher failure rates. Diabetes mellitus is a chronic disease that goes in with hyperglycemia and causes multifarious side effects. Diabetes as a relative contraindication for implant surgery is controversially...

Figure 8. There were moderately significant and po...

    Figure 8. There were moderately significant and positive correlations between the ALP levels and OC levels at all measurements from week 1 to week 12. The OC levels in pg/μg protein were associated with the ALP levels in nM/μg protein at the implant site (a), control site (b), and pooled samples of the control and implant sites (c)

Figure 7. Comparison between biomarker levels & IS...

  Figure 7. Comparison between the trend of the biomarker levels and the trend of the ISQ values over time

Figure 6. There were weakly significant and positi...

  Figure 6. There were weakly significant and positive correlations between the ALP or OC levels and ISQ values at all measurements from week 1 to week 12. At the implant site, the ALP levels in nM/μg protein (a) or the OC levels in pg/μg protein (b) were associated with ISQ values

Figure 5. Change in the median values of the OC le...

  Figure 5. Change in the median values of the OC level over time. In the test group, the OC level continuously increased with time. There was a statistically significant increase in the OC level at 6, 8, 10, and 12 weeks when compared with 1 week (P 

Figure 4. Change in the median values of the ALP l...

  Figure 4. Change in the median values of the ALP level over time. In the test group, the ALP level decreased at 1–4 weeks and then increased at 6, 8, 10, and 12 weeks. There was no statistically significant difference in the ALP level in either the control or the test groups at any measurement

Figure 3. Change in the median values

    Figure 3. Change in the median values of the GCF (control group) and PICF (test group) volume over time. In the test group, the PICF volume continuously decreased with time (a). There were no significant differences in the median values of the crevicular fluid volume in either the control group or the test groups at any measurement (b)

Figure 2. Change in the mean ISQ values over time

  Figure 2. Change in the mean ISQ values over time. There was a statistically significant decrease in the mean ISQ values between 1 and 3 weeks (P 

Figure 1. Timeline of the clinical study

  Figure 1. Timeline of the clinical study. I—implant site, T—contralateral posterior mandibular nonsurgical tooth

Table 5 Crevicular fluid ALP and OC levels

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Median (interquartile range) ALP level  (nM/μg protein)   Tooth (control) 175 (215) 203 (308) 148 (269) 143 (112) 266 (427) 145 (96) 181 (148) 191 (263) 107 (128)   Implant (test) 230 (238) 139 (139) 157 (293) 108 (134) 166 (434) 179 (251) 147 (...

Table 4 Crevicular fluid volume

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Median (interquartile range) CF volume (μl)  Tooth (control) 0.20 (0.23) 0.26 (0.25) 0.19 (0.20) 0.19 (0.50) 0.17 (0.33) 0.18 (0.08) 0.13 (0.24) 0.23 (0.42) 0.20 (0.17)  Implant (test) 0.26 (0.30) 0.25 (0.41) 0.16 (0.21) 0.17 (0.19) 0.18 (0.33) 0.13 (0.14) ...

Table 3 ISQ values according to gender and bone qu...

Time Day 0 1 week 2 weeks 3 weeks 4 weeks 6 weeks 8 weeks 10 weeks 12 weeks Mean ISQ values 77.0 ± 1.32 65.6 ± 2.70a 70.5 ± 2.03a 72.1 ± 1.64a 74.2 ± 1.65 76.1 ± 1.33 78.1 ± 1.38 78.2 ± 1.32 79.6 ± 1.06 Gender  Male (n = 3) 77.0 ± 0.58 59.7 ± 4.62 71.7 ± 3.24 75.0 ± 1.89 7...

Table 2 Profile of patients

Patient no. Age Sex Positiona Bone qualityb 1 34 Female 46 3 2 38 Female 36 3 3 43 Female 37 3 4 64 Male 46 2 5 30 Female 47 3 6 48 Female 36 2 7 57 Male 36 3 8 28 Female 46 3 9 33 Male 46 2 10 49 Female 46 3

Table 1 Inclusion and exclusion criteria

Inclusion criteria Exclusion criteria Patients aged 25–65 years Presence of periodontal disease or periapical lesions Ability to participate in this study History of bone augmentation at the implant site in the past 6 months No systemic diseases (e.g., diabetes, osteoporosis, hypertension, etc.) History of tooth extraction at the implant site in the past 6 months ...

Reference : Relation between the stability of dent...

References Albrektsson T, Brånemark PI, Hansson HA, Lindström J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155–70. Khongkhunthian P. Implant features. In: Khongkhunthian P, editor. PW Plus Thai Dental Implant. Bangkok: STZ Mospace design; 2015. p. 12. Lacey DL, Timms E, Tan HL, Kelle...

Discussion : Relation between the stability of den...

Regarding the relationship between the ISQ values and ALP or OC levels, although the ISQ values were weakly correlated with the bone markers (r = 0.226 for ALP level and r = 0.245 for OC level, P = 0.05), there were significant and positive correlations between the ISQ values and ALP or OC levels at all measurements from week 1 to week 12. These results are in harmony with the ...

Discussion : Relation between the stability of den...

That study showed that PICF volume decreased significantly from week 1 to week 3. Alteration of the gingival fluid volume and contents occur according to the condition of the tissues surrounding the teeth. The presence of inflammation increases the gingival fluid volume. Also, changes in peri-implant crevicular fluid contents and volume result from the condition of the peri-implant tis...

Discussion : Relation between the stability of den...

Discussion The results of this study show that, at the time of implantation, the ISQ values ranged between 67.5 and 83. The mean initial ISQ value was 77.0 ± 1.32. These findings are in harmony with those of previous studies. Tallarico et al. (2011) reported that the macro-design of dental implant affects the primary anchorage. They suggested that the high initial ISQ value is a factor...

Results : Relation between the stability of dental...

Results Ten patients, seven females, and three males, aged 42.4 ± 11.99 years (range, 28 to 64 years), with either a first mandibular or second mandibular molar edentulous area, who required a single nonsubmerged implant participated in this study, as shown in Table 2. The implants used for all patients were 10 mm long and 5 mm in diameter. All patients completed the follow-up. None of t...

Methods : Relation between the stability of dental...

The color in the wells changed from blue to yellow. After that, the color solution in each well was measured at 450/540 nm within 30 min. The OC level in each sample was calculated from a standard curve and normalized by total protein. The level of the ALP activity was measured by colorimetric analysis. Briefly, 80 μl of sample solution were added into each well of a 96-well microplate, and t...

Methods : Relation between the stability of dental...

  Sample preparation and analysis GCF/PICF in the Periopaper strip was eluted by adding 320 μl quantity of phosphate-buffered saline (PBS) into the sample tube and incubated at 4 °C, overnight. The eluted protein solution from each gingival fluid sample was used for the biochemical analysis. Total protein in the gingival fluid sample was measured by the Bradford analysis. Briefly, a 10 μl...

Methods : Relation between the stability of dental...

  RFA assessments At implant placement and after 1, 2, 3, 4, 6, 8, 10, and 12 weeks, RFA assessments were performed using the Osstell® ISQ (Integration Diagnostics AB, Goteborg, Sweden) according to the manufacturer’s instructions. A Smartpeg™ (type 47) (Integration Diagnostics AB) was screwed to the implant using a Smartpeg mount. After Smartpeg mount removal, the RFA assessment was perf...

Methods : Relation between the stability of dental...

Methods The study is a prospective clinical study during the 3-month healing period of implant. The study was approved by the Human Experimentation Committee, Faculty of Dentistry, Chiang Mai University. The study outline is shown in Fig. 1. Patients Ten patients, who were partially edentulous in the mandibular posterior region for whom a single nonsubmerged implant was planned, participated ...

Background : Relation between the stability of den...

The second phenomenon is contact osteogenesis, in which bone formation takes place from the implant surface toward the local bone. This osteogenesis consists of the early phase of osteogenic cell migration, osteoconduction, and de novo bone formation. The de novo bone formation at a solid surface has four stages. The first stage is secretion of the two noncollagenous proteins, osteopontin, and bon...

Background : Relation between the stability of den...

Background Dental implants have shown a high success rate for rehabilitation of edentulous patients if certain conditions are met during treatment. Nevertheless, the risk of failure remains difficult to predict. The achievement of osseointegration depends on many factors, such as a suitable host, biocompatible materials, careful surgery, and an appropriate healing time. The primary stability c...

Relation between the stability of dental implants ...

Relation between the stability of dental implants and two biological markers during the healing period: a prospective clinical study Abstract Objectives The purposes of this study were to examine the correlation between the stability of dental implants and bone formation markers during the healing period and to monitor the stability of dental implants using the resonance frequency analysis (R...

Figure 3. Postoperative radiograph of the resected...

Figure 3. Postoperative radiograph of the resected dental implant in the right anterior maxilla

Figure 2. On radiological examination

  Figure 2. On radiological examination, it was confirmed that the dental implant had perforated the cortical bone of the right nasal floor

Figure 1. On anterior rhinoscopy, the apical part ...

  Figure 1. On anterior rhinoscopy, the apical part of the titanium dental implant in the right anterior maxilla was seen in the nasal floor close to the nasal septum

Discussion

Discussion Insertion of endosseous dental implants is usually associated with a low incidence of complications and excellent prognosis. However, physiologic changes following tooth loss may complicate or even impede insertion of dental implants in the upper jaw. Furthermore dental implants can only be inserted if there is sufficient bone for adequate stabilization. Therefore, in severely at...

Background & case presentation

Background Endosseous dental implants are commonly used to rehabilitate fully or partially edentulous patients. The insertion of such implants can in some cases cause complications, especially in the edentulous atrophic maxilla. In this paper, an unusual complication of altered nasal airflow after the placement of an endosseous dental implant in the maxilla is presented. Subsequent treatmen...

Altered nasal airflow: an unusual complication fol...

Altered nasal airflow: an unusual complication following implant surgery in the anterior maxilla Abstract Dental implants have been in routine clinical use for over three decades and are a predictable treatment modality. However, as with all other aspects of dentistry, complications occur. A 50-year-old female patient with complaints of a long ongoing unpleasant altered nasal airflow presented...

Table 1 Statistical analysis of individual paramet...

  Zygomatic implant group   Conventional implant group     Variable N Mean PD IC 95 % N Mean PD IC 95 % p Overall satisfaction 14 8.88 0.71 −1.17/−0.38 14 9.65 0.13 −1.19/−0.36 0.001 Stability 14 9.79 0.54 −0.50/0.09 14 10.00 0.00 −0.52/0.11 0.009 Ease of cleaning 14 5.82 1.99 −3.49/−1.14 14 8.15 0.78 −3....

Figure 8. Visual analog scale—evaluator version

Figure 8. Visual analog scale—evaluator version

Figure 7. Visual analog scale—patient version

  Figure 7. Visual analog scale—patient version

Figure 6. Zygomatic implant probing using a WHO pe...

  Figure 6. Zygomatic implant probing using a WHO periodontal probe

Figure 5. Coronal slice from the CBCT showing smal...

  Figure 5. Coronal slice from the CBCT showing small exteriorization of a zygomatic implant apex

Figure 4. Coronal slice from the CBCT showing impl...

  Figure 4. Coronal slice from the CBCT showing implant apical third inside the zygomatic bone

Figure 3. Panoramic radiograph showing bone level ...

Figure 3. Panoramic radiograph showing bone level maintenance around the conventional implants

Figure 2. Periapical radiographs using the paralle...

  Figure 2. Periapical radiographs using the parallelism technique. a Conventional implants—anterior. b Conventional implants—posterior

Figure 1. a Brånemark technique. b Sinus slot ...

Figure 1. a Brånemark technique. b Sinus slot technique. c Extrasinus technique

Reference : Evaluation of patients undergoing plac...

References Stievenart M, Malevez C. Rehabilitation of totally atrophied maxilla by means of four zygomatic implants and fixed prosthesis: a 6–40-month follow up. Int J Oral Maxillofac Surg. 2010;39:358–63. Van der Mark EL, Bierenbroodspot F, Baas EM, De Lange J. Reconstruction of an atrophic maxilla: comparison of two methods. Br J Oral Maxillofac Surg. 2011;49:198–202. Pelo S, Gasp...

Discussion : Evaluation of patients undergoing pla...

The prostheses supported by zygomatic implants have a special design due to the location and a more palatal emergence profile of the implants in position when compared to conventional implants. This situation can hinder the tongue position and hygiene of the prosthesis and interfere with function. Some studies conducted an assessment of the level of patient satisfaction on the prosthesis sup...

Discussion : Evaluation of patients undergoing pla...

Nakai et al. performed this exam 6 months following the placement of 15 zygomatic implants in nine patients and found an absence of signs and symptoms of sinusitis. Maló et al. evaluated the association between zygomatic implants and maxillary sinusitis using sinusoscopy on 14 patients and found no cases of infection or inflammation of the mucosa surrounding the implants, demonstrating that...

Discussion : Evaluation of patients undergoing pla...

Becktor et al. report that patients with oral-sinus communication may develop suppuration with or without sinusitis. In such cases, treatment consists of the administration of antibiotics and/or the repositioning of the soft tissue and maintenance of a stable zygomatic implant, with no reports of the recurrence of sinusitis. Brånemark found fistula in five patients both before and aft...

Discussion : Evaluation of patients undergoing pla...

Becktor et al. report that patients with oral-sinus communication may develop suppuration with or without sinusitis. In such cases, treatment consists of the administration of antibiotics and/or the repositioning of the soft tissue and maintenance of a stable zygomatic implant, with no reports of the recurrence of sinusitis. Brånemark found fistula in five patients both before and aft...

Discussion : Evaluation of patients undergoing pla...

Other studies have reported the presence of problems with oral tissue in the region of the zygomatic implants, including infection and swelling, usually associated with loss of implant apical osseointegration. Hirsch et al. have reported the presence of hyperplasia, mucositis, and infection in eight patients in a total of ten throughout the monitoring period. Although certain criteria to ev...

Discussion : Evaluation of patients undergoing pla...

Our study demonstrated the absence of pain as well as of pus or bleeding on probing and palpation for both zygomatic and conventional implants, with good bone level for conventional implants. No periimplant radiolucency was noted around the conventional implants and in the apical portion of the zygomatic implants. These findings are similar to the studies of Stiévenart and Malevez, Peñarro...

Discussion : Evaluation of patients undergoing pla...

As described by Hirsch et al., Aparicio et al., and Farzad et al., this criteria was assessed by periapical radiographs obtained by the parallelism technique combined with panoramic radiographs for conventional implants and CT scans for zygomatic implants. The bone loss was defined as a vertical change of bone level measured from the most inferior line of implant exposure. All previous studi...

Discussion : Evaluation of patients undergoing pla...

Discussion The morbidity caused by bone graft harvesting and the delay in the final treatment due to the time necessary for bone incorporation triggered the development of techniques without grafting as an option for the treatment of patients with edentulous jaws. Brånemark in 1998 developed a novel technique for placing implants in the zygomatic bone to treat severely atrophic maxilla wit...

Results : Evaluation of patients undergoing placem...

  Evaluation of the maxillary sinus health Among the 14 patients submitted to zygomatic implants, only three reported having had nasal obstruction in the weeks preceding the evaluation. One of these patients had a cold, and the other two reported having self-medicated with antihistamines 1 week prior to the evaluation, with the subsequent disappearance of nasal obstruction. Only one patient re...

Results : Evaluation of patients undergoing placem...

Results Of the 17 operated patients, 14 were included in the study and 2 were excluded for not having enough data in the chart and 1 for refusing to return for evaluation of sinus health, totalizing 27 zygomatic implants and 55 conventional implants in group I, without losing any implant, representing 100 % survival of implants placed. The minimum follow-up was 15 and the maximum was 53 month...

Methods : Evaluation of patients undergoing placem...

For patients with signs indicating maxillary sinusitis, a quality of life questionnaire was administered and video-assisted nasal fibroscopy was performed. The aim of the clinical exam was to investigate signs of sinusitis: (a) nasal obstruction, using a visual analog scale (VAS) ranging from 0 to 10 points, on which the patient marked his/her degree of obstruction, with the examiner’s subseque...

Methods : Evaluation of patients undergoing placem...

A ruler template with the respective magnifications was used, considering 25 to 0 % for panoramic and periapical radiographs, respectively. Additionally, the radiographic criteria recommended by Buser et al. were included to determine the success of the implants. These criteria consist of the absence of persistent radiolucency around the implant. The zygomatic implants were assessed only to verify...

Methods : Evaluation of patients undergoing placem...

All patients were rehabilitated with Conexão® implants system. The inclusion criteria for group I were patients with severe maxillary resorption, classified as classes IV and V of Cawood and Howell (1988), receiving zygomatic implants using Stella and Warner’s technique, performed by the Oral and Maxillofacial Surgery Department from the Rio Grande do Norte Federal University, and having full ...

Methods : Evaluation of patients undergoing placem...

The hypothesis of this study was to analyze if Stella and Warner’s technique have high survival rates and their rehabilitation have similar satisfaction when compared to total fixed prostheses with conventional implants. Radiographic evaluation Panoramic and periapical radiographs were obtained for conventional and zygomatic implants in group I (Figs. 2.a.b and 3). The purpose was to evaluate ...

Methods : Evaluation of patients undergoing placem...

Methods This retrospective cohort study was submitted and approved by the Hospital Research Ethics Committee, receiving the registration number 137/201. The sample consisted of 28 patients (21 females and 7 males), with age ranging from 46 to 63 years, and all of them have undergone either the placement of zygomatic implants using the Stella and Warner’s technique or conventional implants, ...

Background : Evaluation of patients undergoing pla...

Background The prosthodontic rehabilitation of patients with atrophic maxilla is a challenge for a clinician due to the severe compromise of masticatory function and speech with a significant quality of life impact. The poor bone volume found on these patients makes it difficult for conventional rehabilitation with fixed prosthesis and to insert dental implants. Different surgical techniques w...

Evaluation of patients undergoing placement of zyg...

Abstract Background This study aimed to evaluate patients undergoing placement of zygomatic implants by Stella and Warner’s technique, considering the survival rate of conventional and zygomatic implants, and assess the health of the maxillary sinuses and the level of patient satisfaction. Methods In this retrospective cohort study, 28 patients had received a combination of conventional an...

Table 7 Meta-regression—effect of surface and le...

Type III tests of fixed effects   Num Den     Effect DF DF F value P Surface 1 11 0.84 0.3787 Length 7 11 0.97 0.4951 Location 1 11 0.00 0.9868

Table 6 Heterogeneity statistics

Q P   2.7008 0.7460   I 2 ci− ci+ 0.00 % 0.00 % 74.62 % τ 2 ci− ci+ 0.0000 0.0000 0.0069

Table 5 Meta-analysis implant data—pooled analys...

Authors Number Success ci− ci+ Weight (%) Polizzi et al. 38 0.921 0.810 0.990 12.71 Friberg et al. 13 1.000 0.872 1.000 4.46 Tawil and Younan 109 0.945 0.893 0.981 36.14 Khayat et al. 111 0.946 0.895 0.982 36.80 Deporter et al. 14 1.000 0.881 1.000 4.79 Schincaglia et al. 15 1.000 0.888 1.000 5.12   300 0.963 0.9...

Table 4 Implants used in the maxilla and mandible

Study Implant surface Implant type No. of implants in maxilla (no. failed) No. of implants in mandible (no. failed) % survived in maxilla % survived in mandible Khayat et al. 2001 Acid-etched, uncoated Zimmer (Screw vent, Paragon) 49 (2) 62 (4) 95.9 93.5 Deporter et al. 2001 Sintered porous Endopore (Innova Corp) 0 14 (0) – 100 Schincaglia et al. 2008 ...

Table 3 Wide machined implants

Study Implant surface Implant type Implant length No. of implants No. failed % survived Polizzi et al. 2000 Machined Brånemark (Nobel Biocare) 7 2 0 100 8.5 8 1 87.5 10 15 1 93.3 11.5 13 1 92.3 Friberg et al. 2000 Machined Brånemark (Nobel Biocare) 6 13 0 100 Tawil and Younan 2003 Machined Brånemark (Nobel Biocare) 6 16 0 ...

Table 2 Wide surface-treated Implants

Study Implant surface Implant type Implant length No. of implants No. failed % survived Khayat et al. 2001 Acid-etched, uncoated Zimmer (Screw vent, Paragon) 8 29 2 93.1 10 45 4 91.1 13 28 0 100 16 15 0 100 Deporter et al. 2001 Sintered porous Endopore (Innova Corp) 7 14 0 100 Schincaglia et al. 2008 Ti-unite Mark III WP (Nobel B...

Table 1 Wide-diameter implants

Implant diameter (mm) Implant lengths No. of implants (total) Implant type Implant surface Prospective clinical study Placement follow-up/mean (range) Implant survival (%) Age range (years) 4.7 8, 10, 13, 16 117 Zimmer (Screw vent, Paragon) Acid-etched, uncoated Khayat et al. 2001 Healing 3–6 months plus 17 months loading (11–21 months) 95 – 5.0 7 14 ...

Figure 3. Funnel plot

Figure 3. Funnel plot Figure 3. Funnel plot

Figure 2. Forest plot

  Figure 2. Forest plot

Figure 1. Study selection for wide-diameter implan...

  Figure 1. Study selection for wide-diameter implant articles

Conclusion : A meta-analysis on the effect of impl...

Conclusions This meta-analysis concluded that the location, length, and surface treatment of the wide-diameter implant do not significantly affect its survival. It is therefore suggested with caution that when the conditions of the implant site corresponds to the inclusion criteria used in our meta-analysis, choosing a wide implant in the posterior mandible or maxilla, where implant length may ...

Discussion : A meta-analysis on the effect of impl...

This suggests that the implant surface characteristics may have an impact on implant survival rate based on the implant diameter, and as the diameter of the implant is increased, as in the wide-diameter implant, this impact mConversely, Maló and Araújo Nobre reported significantly more failures for machined compared to surface-treated narrow (3.3-mm diameter) implants.ay not be stati...

Discussion : A meta-analysis on the effect of impl...

The present meta-analysis was limited to prospective clinical studies and utilized a rigorous inclusion and exclusion criteria. Studies included in the analysis were limited to cases in which implants placed in sites with adequate bone volume without grafting. Implants were placed in healed sites and loaded after at least 1–3 months of healing. All studies had at least 1-year follow-up. Pa...

Results : A meta-analysis on the effect of implant...

Results Of the six studies selected, three evaluated surface-treated implants and three machined implants (Table 1). The included studies all used similar criteria for implant survival, which was defined as the absence of mobility, pain, and radiolucent lesions. The implant survival was based on the percentage of implants evaluated, and the implant lengths in the studies range from 6 to 16 mm (Ta...

Materials and methods : A meta-analysis on the eff...

Screening and selection Two reviewers participated in selection of studies (MT and MP). At the initial phase of selection, abstracts and titles of articles were screened by one reviewer (MT) to exclude articles that clearly were not related to wide-diameter dental implants. The previously described inclusion and exclusion criteria were applied when including articles for full-text screening. When...

Materials and methods : A meta-analysis on the eff...

Materials and methods Focused question Does length of the wide-diameter implant influence its survival? Does the surface modification influence its survival compared to machined implant surfaces? Does the implant placement in the maxilla or the mandible influence its survival? Literature search and study design The database on PubMed, Web of Science, and Cochrane Central Register of Cont...

Review : A meta-analysis on the effect of implant ...

Review Introduction Endosseous implants were used reliably in the treatment of various degrees of edentulism. In restoring the edentulous ridge, the clinician could be faced with difficult bony situations. The wide-diameter implant could be used in these situations to improve primary stability by increasing the surface area available for osteointegration. Biomechanically, the wide-diameter imp...

A meta-analysis on the effect of implant character...

A meta-analysis on the effect of implant characteristics on the survival of the wide-diameter implant Abstract The purposes of the study are to study the implant survival of the wide-diameter implant and to analyze if the length, the implant surface, or the placement location has any effect on its survival. Electronic databases were searched from inception to Dec 2014. Studies included in the ...

Figure 2. Figure illustrating the proposed mucosal...

  Figure 2. Figure illustrating the proposed mucosal thickening index. A ≤1 mm, indicating no thickening; B >1 mm but ≤2 mm, indicating minimal thickening; C >2 mm but ≤5 mm, indicating moderate thickening; D >5 mm, indicating severe thickening

Table 2 Statistical results after inter-variable a...

Table 2 Statistical results after inter-variable adjustment showing the association between recorded parameters and sinus mucosal thickening; p values that showed statistically significant differences are italicized       Gender Respiratory diseases Cardio-vascular diseases Diabetes mellitus Smoking History of periodontal diseases Endodontic treatment History of orthodontic t...

Table 1 CBCT measurements of sinus mucosal thicken...

Table 1 CBCT measurements of sinus mucosal thickening Patient Anterior(E1-floor of the sinus) Middle(C1-floor of the sinus) Posterior(D1-floor of the sinus) Thickest(F-floor of the sinus) 1 3.06 0.32 0.76 4.59 2 0.34 0.21 0.20 0.34 3 0.39 0.54 1.38 1.66 4 4.15 3.79 0.61 6.36 5 5.64 1.33 3.73 8.42 6 7.34 0.77 0.86 7.66 7 1.9...

Figure 1. Figure illustrating the reference points...

  Figure 1. Figure illustrating the reference points of the CBCT measurements. A: most posterior point of the sinus wall; B: most anterior point of the sinus wall; C: mid-point between A and B; C1: measurement of mucosal thickening perpendicular to A–B line at point C; D: mid-point between A and C; D1: measurement of mucosal thickening perpendicular to A–B line at point D...

Reference : Dental implants and grafting success r...

Shahbazian M, Vandewoude C, Wyatt J, Jacobs R. Comparative assessment of panoramic radiography and CBCT imaging for radiodiagnostics in the posterior maxilla. Clin Oral Investig. 2014;18:293–300. Logan GM, Brocklebank LM. An audit of occipitomental radiographs. Dentomaxillofac Radiol. 1999;28:158–61. Pazera P, Bornstein MM, Pazera A, Sendi P, Katsaros C. Incidental maxillary sinus findings...

Reference : Dental implants and grafting success r...

Shanbhag S, Karnik P, Shirke P, Shanbhag V. Cone-beam computed tomographic analysis of sinus membrane thickness, ostium patency, and residual ridge heights in the posterior maxilla: implications for sinus floor elevation. Clin Oral Implants Res. 2014;25:755–60. Gardner DG. Pseudocysts and retention cysts of the maxillary sinus. Oral Surg Oral Med Oral Pathol. 1984;58:561–7. Chiapasco M, Pa...

Reference : Dental implants and grafting success r...

References Beretta M, Poli PP, Grossi GB, Pieroni S, Maiorana C. Long-term survival rate of implants placed in conjunction with 246 sinus floor elevation procedures: results of a 15-year retrospective study. J Dent. 2015;43:78–86. Del Fabbro M, Corbella S, Weinstein T, Ceresoli V, Taschieri S. Implant survival rates after osteotome-mediated maxillary sinus augmentation: a systematic revi...

Discussion : Dental implants and grafting success ...

This study presents new data on maxillary sinus mucosal thickening derived from a carefully defined data set; however, there were some limitations in the study. One limitation was the limited sample size. However, as discussed, our stringent case selection criteria yielded a more uniform data set for analyses. Other limitations were related to the actual measurements of the maxillary sinus. ...

Discussion : Dental implants and grafting success ...

Our study did not find a significant association between endodontically treated teeth and mucosal thickening. Though this finding is consistent with some previously published studies, other studies did report an association. These discrepant findings could be the result of different inclusion criteria in the study design. Since our study did not include any patients with radiographic signs o...

Discussion : Dental implants and grafting success ...

The current study demonstrated that sinus mucosal thickening does not correlate with implant survival. This result is consistent with a previously published report by Jungner et al. In their study, the presence of sinus thickening was not significantly associated with implant failure. Similarly, our study found a 100% implant survival rate for both patients with and without sinus mucosal thi...

Discussion : Dental implants and grafting success ...

Discussion CBCT imaging has been recognized as a more sensitive imaging modality for identifying sinus thickening and pathoses in the posterior maxilla compared to panoramic radiography. This could explain why the current study identified a higher prevalence of mucosal thickening compared to earlier studies. However, compared to other similar CBCT studies, the prevalence reporte...

Results : Dental implants and grafting success rem...

Results Twenty-nine CBCT images (11 females and 18 males) were included in this study. All the implants placed in these included cases survived, representing a 100% implant survival rate. With regards to measurements of mucosal thickening, the intra-examiner reproducibility revealed an exact intra-examiner correlation of 99%, with a p value of 0.40 for a t test for independen...

Methods : Dental implants and grafting success rem...

In order to standardize the measurements for each sinus, each scan was carefully oriented in the axial, coronal, and sagittal plane. In the axial plane, a horizontal line from the right and left zygoma was chosen as the standard. Orienting the hard palate horizontally was the standard in the coronal plane as well as in the sagittal plane. The specific teeth that were to be replaced by implants wer...

Methods : Dental implants and grafting success rem...

Given these specific inclusion and exclusion criteria and the specific purpose of this study, only 29 cases qualified for inclusion from an original screen of approximately 4000 cases. An initial search of our database resulted in a larger number of cases that would theoretically qualify; however, further investigation revealed the need to exclude a great number of cases. The reasons for exclusion...

Methods : Dental implants and grafting success rem...

Methods Study design Our study hypothesis was that mucosal thickening of more than 2 mm and up to 1/3 of the volume of the sinus would not alter the predictability for SFE and dental implant placement. The primary outcome was to determine the success rate of dental implant placement in augmented maxillary sinus areas with mucosal thickening. A secondary outcome was to evaluate the effect of g...

Background : Dental implants and grafting success ...

Background Despite the high survival rate of dental implants inserted in maxillary sinuses that have undergone sinus floor elevation (SFE) with bone grafting, complications still occur. Sinus membrane perforation is reported to be the most common complication. Postoperative maxillary sinusitis is less common (0–22%); nevertheless, it could potentially compromise the outcome of...

Dental implants and grafting success remain high

Dental implants and grafting success remain high despite large variations in maxillary sinus mucosal thickening Abstract Background Although mucosal thickening is the most common radiographic finding observed regarding sinus pathology, the knowledge regarding its clinical significance on the outcomes of dental implants and grafting in the maxillary sinuses is still limited. We hypothesized th...

Figure 5. Periapical X ray after 1 year of follow-...

  Figure 5. Periapical X ray after 1 year of follow-up, the bone was stable and no sign of peri-implantitis was shown

Figure 4. Follow-up after 1 year, no radiographic ...

  Figure 4. Follow-up after 1 year, no radiographic sign was appreciating and the osseointegration was satisfactory

Figure 3. Final restaurations: The parallelism of ...

  Figure 3. Final restaurations: The parallelism of the implants is achieved by carving the non-submerged part a occlusal view and b lingual view

Figure 2. Flapless surgical technique, atraumatic ...

  Figure 2. Flapless surgical technique, atraumatic surgical procedure for zirconium implants using the circular scalpel (a)–sharp, clean cut without bleeding (b)

Figure 1. Diagnostic radiographic exploration prev...

Figure 1. Diagnostic radiographic exploration previous to treatment

Discussion : Zirconia implants and peek restoratio...

To avoid exceeding the adaptive limits of the bone and maintain the proper stimulation of mechanical stress that will keep the bone vital, PEEK components seem a viable alternative to obtaining a similar modulus to that of cortical bone. In this way, bone could be stimulated, favouring remodelling without overload. It would concentrate the load by absorbing and distributing the same. Its cap...

Discussion : Zirconia implants and peek restoratio...

Discussion Intraoral conditions (saliva pH, acidic drinks, bacterial plaque, etc.) interact with metals, increasing corrosion, a phenomenon that also affects titanium implants. Amongst other reasons, this is whereby patients increasingly request the use of materials free of metallic alloys. In response to this growing demand, zirconia implants are considered an alternative, due to their low...

Case : Zirconia implants and peek restorations for...

Case presentation A patient who is a 45-year-old woman and non-smoker has no medical record of interest. The patient complained of pain in the right second upper molar. She said that she felt intense pain while chewing. The pain was accentuated with occlusion and while chewing, making normal functioning impossible. The patient mentioned the absence of piece 16, which had been extracted 8 years...

Background : Zirconia implants and peek restoratio...

Background In the field of implant dentistry, the most widely used implants over the past 40 years are those manufactured from titanium, which are still the most popular. The recent demands for materials without metal alloys in dentistry, together with the increased sensitivity and allergies of some patients, have promoted the development of new materials. An example of this is zirconia-based...

Zirconia implants and peek restorations for the re...

Abstract Background One of the disadvantages of the zirconia implants is the lack of elasticity, which is increased with the use of ceramic or zirconia crowns. The consequences that could result from this lack of elasticity have led to the search for new materials with improved mechanical properties. Case presentation A patient who is a 45-year-old woman, non-smoker and has no medical record...

Table 2 Descriptive statistics of the experimental...

BIC 3M™ ESPE™ MDIs Ankylos® Friadent (Dentsply) Median 58.5 57 Mean 57 56.5 Interquartile range 8 5.5 First quartile 53.25 53.75 Third quartile 61.25 59.25

Table 1 Comparison of % BIC in both groups

Sample 3M™ESPE™ MDIs Ankylos® 1. 67 54 2. 59 67 3. 54 45 4. 51 58 5. 47 57 6. 64 49 7. 50 54 8. 60 56 9. 56 60 10. 61 53 11. 62 59 12. 61 55 13. 59 59 14. 45 51 15. 58 59 16. 54 62 17. 66 62 18. 56 57  

Figure 6. Micro CT scan images of the MDIs and Ank...

  Figure 6. Micro CT scan images of the MDIs and Ankylos® embedded in rabbit bone 6 weeks post implantation

Figure 5. Histological section of standard implant...

Figure 5. Histological section of standard implant in rabbit tibia stained with methylene blue and basic fuchsin  

Figure 4. Histological section of mini dental impl...

  Figure 4. Histological section of mini dental implant in rabbit tibia stained with methylene blue and basic fuchsin

Figure 3. Histological sections being obtained wit...

Figure 3. Histological sections being obtained with Leica SP 1600 saw microtome

Figure 2. Leica SP 1600 saw microtome

Figure 2. Leica SP 1600 saw microtome

Figure 1. Radiograph showing implants in the rabbi...

  Figure 1. Radiograph showing implants in the rabbit tibia

Discussion : Osseointegration of standard and mini...

Our study is also in concordance with the results of a removal torque study by Simon et al. in immediately loaded “transitional endosseous implants” in humans. The percentage BIC for MDIs was similar to standard implants. The surface topography also affects the BIC, Wennerberg et al. measured and compared removal torque values on screw-shaped titanium implants with three surface types. ...

Discussion : Osseointegration of standard and mini...

Discussion The osseointegration potential of 3M™ESPE™ MDIs has not been studied. The MDI is a one-piece implant that simplifies the restorative phase resulting in a reduced cost for the patient. Titanium-aluminum-vanadium alloy (Ti 6Al-4V-ELI) is used for increased strength. The success of these implants led to its use in long-term fixed and removable dental prostheses. Conventional imp...

Results : Osseointegration of standard and mini de...

Results Clinical findings On the whole, postoperative wound healing in all the rabbits was good. None of them exhibited any signs of wound infection or exposure. A total of 36 specimens were retrieved for histological examination. Histological observations All of the implants in both groups showed osseointegration and displayed a good amount of bone contact length (Figs. 4 an...

Methods : Osseointegration of standard and mini de...

The built-in water cooling device prevents overheating of the object and removes saw dust from the cutting edge and thus prolongs the lift time of the saw blade. The most favorable feed rate was determined (Fig. 3). After trimming, the first undefined slice was removed from the saw blade. The desired section thickness was selected, considering the thickness of the saw blade and added to the desire...

Methods : Osseointegration of standard and mini de...

  Sample preparation for embedding The specimens were dehydrated in the ascending graded ethanol solution and kept in a pre-filtration solution for 3 h at room temperature and then in the filtration solution at 4 °C for 17 h. The specimens were then embedded in a light curing resin Technovit 9100 NEW (Kulzer & Co., Wehrheim, Germany) polymerization system based on methyl methacrylate, speci...

Methods : Osseointegration of standard and mini de...

The skin was sutured to a primary closer with the same suture material. Radiograph Plain X-ray images of all the rabbit tibia were taken after suturing to confirm the position of implants and to detect any injury/fracture of the bone (Fig. 1). Post surgical treatment After the surgical procedure, the animals were housed in a cage under the supervision of a veterinary doctor until they came out...

Methods : Osseointegration of standard and mini de...

After mobilizing the mucoperiosteal flap, the 3-mm center punch was used to register a guide for the twist drill. The twist drill was used to establish the axial alignment of the implant and to assist in the guidance of the depth drill. The depth drills were sequentially used to create osteotomy to the subcrestal axial depth of 0.5 mm. The conical reamer was used to develop the conical shape of t...

Methods : Osseointegration of standard and mini de...

Antiseptic skin preparation was done starting at the center of the surgical site and moved to the outside of the prepared area in a circular manner. Three scrubs with 2% chlorhexidine solution and three alternating rinses with alcohol were performed. The animal was draped and fixed with clamps on a sterile, impermeable covering to isolate the disinfected area. This was performed by the gloved and ...

Methods : Osseointegration of standard and mini de...

Methods Animal model Nine clinically healthy New Zealand white rabbits weighing 3.5 kg and more were used for the study, and the animals were housed in the central animal house facility. The head of tibia/femur of the animals were used for the implantation of samples. Rabbits’ tibiae and femur have been widely used as an animal model by various other authors to study osseointegration of dent...

Background : Osseointegration of standard and mini...

Considerable confusion exists in the literature regarding the best method to monitor the status of a dental implant. Various methods have been used to demonstrate the osseointegration of dental implants. A common and time-tested method to evaluate biological responses to an implant is to measure the extent of bone implant contact (BIC), referred to as histomorphometry at the light microscopic leve...

Background : Osseointegration of standard and mini...

Background The term “osseointegration” was first introduced to explain the phenomenon for stable fixation of titanium to bone by Brånemark et al. in the 1960s. Osseointegrated implants were introduced, a new era in oral rehabilitation began, and many studies were conducted. A success rate of over 90% has been reported. Further, a success rate of 81% in the maxillary bone and 91% in the man...

Osseointegration of standard and mini dental impla...

Abstract Background Mini dental implants (MDIs) are becoming increasingly popular for rehabilitation of edentulous patients because of their several advantages. However, there is a lack of evidence on the osseointegration potential of the MDIs. The objective of the study was to histomorphometrically evaluate and compare bone apposition on the surface of MDIs and standard implants in a rabbit m...

Table 2 Outcome success criteria

Implant success Clinically immobile when tested manually and/or with RFA (minimum ISQ = 65) Absence of peri-implant radiolucency present on an undistorted radiograph Absence of unresolved pain, discomfort, infection or neuropathy, or peri-implant soft tissue complications attributable to the implant Implant placement that does not preclude delivery of a prosthetic crown w...

Figure 3. Mean bone loss at 6 months and 1 year

Figure 3. Mean bone loss at 6 months and 1 year. Mean bone loss distribution charts at 6 months and 1 year present no statistically significant difference. p value at 6 months was 0.2981 and at 1 year 0.6613 Figure 3. Mean bone loss at 6 months and 1 year. Mean bone loss distribution charts at 6 months and 1 year present no statistically significant difference. p value at 6 month...

Figure 2. ISQ values at placement, 6 weeks, 6 mont...

  Figure 2. ISQ values at placement, 6 weeks, 6 months, and 1 year. Mean and standard deviation of ISQ values taken at placement, 6 weeks, 6 months, and 1 year is presented. No statistical significant difference was determined between ISQ values at all time points. (p 

Table 1 Patient selection criteria

Inclusion Male or female At least 18 years old Healthy enough to undergo routine implant surgery and subsequent dental treatment Partially edentulous requiring single dental implants in the maxilla Adequate volume of native or grafted bone to accommodate dental implants at least 8 mm long No active infections Physically, emotionally, and financially able to u...

Figure 1. Implant design

  Figure 1. Implant design. The OSPTX and OSP implants are manufactured from high-grade commercially pure titanium with surface roughness produced via a fluoride treatment process. The OSP implant is a screw-shaped self-tapping implant. The diameter used in this study was 4.0 mm. The implant length used in this study was 8 mm. The OSPTX implant has the same features as the OSP except the apex ...

Discussion : Comparative evaluation of the stabili...

Discussion Augmentation of the maxillary sinus prior to dental implant placement is routinely performed in order to help patients restore their maxillary posterior dentition. Unfortunately, not all patients are candidates for this procedure due to either health, personal, or financial concerns. An alternative treatment without the need for a sinus elevation procedure is the use of a shorter...

Results : Comparative evaluation of the stability ...

Results Overall implant survival rate was 93.3%. Two implants failed, one implant in group A (OSPTXSoft) and one in group B (OSPTXStd). Both implant failures occurred at the time of uncovery (at 6 weeks) and prior to loading of the implants and were attributed to lack of integration. With the exception of these two failed implants, there was 100% success for all remaining implants using the par...

Methods : Comparative evaluation of the stability ...

Methods Following proper approval by the LSUHSC Institution Review Board (LSUNO IRB#7438), 27 (30 implant sites) systemically healthy patients at least 18 years old were enrolled in the study and randomly divided into three groups as follows (inclusion and exclusion criteria are described in detail in Table 1): Group A received 10 OSPTX implants using the soft bone surgical protocol (OSPT...

Background : Comparative evaluation of the stabili...

To avoid invasive sinus augmentation procedures, implants have been designed in shorter lengths such as 8 mm. To further enhance short implant primary stability, a tapered design has been developed which has been proven to provide greater initial stability. Implant stability can be evaluated by different measures such as torque at the time of implant placement, resistance to reverse torque, and re...

Background : Comparative evaluation of the stabili...

Background Dental implants are now a widely accepted treatment option for the replacement of missing teeth. The therapeutic goal of dental implants is to support restorations that replace single or multiple missing teeth so as to provide patient comfort, function, and esthetics as well as assist in the ongoing maintenance of remaining intraoral and perioral structures. However, anatomic limitat...

Comparative evaluation of the stability of two dif...

Abstract Background The purpose of this study was to compare a parallel wall design implant to a tapered apex design implant when placed in the posterior maxilla using two different surgical protocols. Methods Twenty-seven patients (30 implants) were divided into three groups. All implants were 4 mm wide in diameter and 8 mm long. Group A received 10 tapered implants (OSPTX) (Astra Tech O...

Figure 15. Intra-oral radiograph showing the impla...

  Figure 15. Intra-oral radiograph showing the implant 12 months after placement

Figure 14. Clinical view showing optimal esthetics...

  Figure 14. Clinical view showing optimal esthetics around the screw-retained definitive all-ceramic crown

Figure 13. Situation after implant placement and r...

  Figure 13. Situation after implant placement and repair of the bony defect with a 1:1 mixture of Bio-Oss® and autologous bone  

Figure 12. The impacted canine has become visible

  Figure 12. The impacted canine has become visible after elevation of a full-thickness palatal flap and removing overlying bone

Figure 11. CBCT image showing the palatal location...

  Figure 11. CBCT image showing the palatal location of the impacted secondary canine

Figure 10. Clinical view showing the failing right...

  Figure 10. Clinical view showing the failing right primary canine

Figure 9. Intra-oral radiograph showing the implan...

  Figure 9. Intra-oral radiograph showing the implant 12 months after placement

Figure 8. The screw-retained definitive all-cerami...

  Figure 8. Clinical view showing optimal esthetics around the screw-retained definitive all-ceramic crown

Figure 7. Clinical view immediately after placemen...

  Figure 7. Clinical view immediately after placement of the provisional implant crown

Figure 6. Situation after implant placement and re...

  Figure 6. Situation after implant placement and restoration of the bony defect with a 1:1 mixture of Bio-Oss® and autologous bone

Figure 5. The implant is placed in the prepared so...

  Figure 5. The implant is placed in the prepared socket

Figure 4. The prepared implant socket and osseous ...

  Figure 4. The prepared implant socket and osseous defect resulting from removal of the buccally impacted secondary canine and the primary canine. Note that the upper part of the alveolar crest is intact

Figure 3. The impacted canine has become visible a...

  Figure 3. The impacted canine has become visible after elevation of a full-thickness buccal mucoperiosteal flap and removing overlying bone

Figure 2. CBCT image showing the buccal location o...

  Figure 2. CBCT image showing the buccal location of the impacted secondary canine

Figure 1. Clinical view showing the failing right ...

  Figure 1. Clinical view showing the failing right primary canine

Discussion : Immediate placement and provisionaliz...

Discussion This case report describes two approaches for immediate replacement of a failing primary canine and an impacted secondary canine, viz. one for impacted cuspids located at the buccal side of the maxilla and one for impacted cuspids located at the palatal side of the maxilla, by an immediately placed and provisionalized single implant. With both approaches, esthetically satisfying ...

Case presentation : Immediate placement and provis...

Case 2 A 45-year-old man consulted our department with an impacted right maxillary canine and a persistent primary canine with evident mobility and in need of removal (Fig. 10). The patient chose for a single implant treatment because he wanted to have a long lasting and fixed solution for the failing tooth. All general health prerequisites were met and intra-oral examination revealed a healthy, ...

Case presentation : Immediate placement and provis...

Next, an open tray impression was made at implant level using a custom acrylic resin impression tray (Lightplast base plates; Dreve Dentamid GmbH, Unna, Germany) and a polyether impression material (Impregum Penta; 3 M ESPE, St. Paul, USA). Finally, a healing abutment (NobelReplace; Nobel Biocare AB) was placed, and any remaining residual space between the implant and the buccal bone wall was fill...

Case presentation : Immediate placement and provis...

One day before surgery, the patient started taking antibiotics (amoxicillin 500 mg, three times daily for 7 days) and using a 0.2 % chlorhexidine mouthwash (Corsodyl; GlaxoSmithKline, Utrecht, the Netherlands) for oral disinfection. Following the administering of local anesthesia (Ultracaine D-S Forte; Aventis Pharma Deutschland GmbH, Frankfurt am Main, Germany), an incision was made on the palata...

Case presentation : Immediate placement and provis...

Case presentation Case 1 A 36-year-old woman consulted the Department of Oral and Maxillofacial Surgery of the University Medical Center Groningen, Groningen, the Netherlands, with a persisting upper right primary canine and impacted secondary canine (Fig. 1). The primary canine had to be removed because of fracture of the crown. The patient did not want to undergo orthodontic treatment, and a...

Background : Immediate placement and provisionaliz...

Background Maxillary canines are the second most impacted teeth (20 % of all impacted teeth); the prevalence in general population is approximately 2 %. Most impacted cuspids are located palatally, with a palatal/buccal ratio of 8:1. There are several known treatment options for impacted canines to align them into the dental arch. The most widely used option is orthodontic traction after surgi...

Immediate placement and provisionalization of an i...

Immediate placement and provisionalization of an implant after removal of an impacted maxillary canine: two case reports     Abstract Single immediate implant replacement is accompanied by excellent survival rates and a favorable esthetic outcome. The objective of this report was to describe a surgical approach for removal of a buccal or palatally located impacted secondary canine, com...

Figure 8. Distribution of the occlusal forces

  Figure 8. Distribution of the occlusal forces. Left column: model-T, right column: model-I, “Natural dentition” indicates the results in model-N under the load during occlusal adjustment

Figure 7. Load-displacement curve of the left cani...

  Figure 7. Load-displacement curve of the left canine

Figure 6. FE model with natural dentition (model-N...

  Figure 6. FE model with natural dentition (model-N). Tooth root is displayed with permeability

Figure 5. Schematic diagram for each phase of the ...

  Figure 5. Schematic diagram for each phase of the load-displacement curve after occlusal adjustment of implants. a: Before loading, only anterior natural teeth were in contact with opposing teeth. Occlusal forces were not yet exerted anywhere. b: When a slight load caused the displacement of the mandible upward by the distance corresponding to the gap, i.e., the quantity of occlusal adjust...

Figure 4. Occlusal adjustment was simulated by alt...

  Figure 4. Occlusal adjustment was simulated by altering the load-displacement curves of the springs

Figure 3. Load-displacement curves of the springs

  Figure 3. Load-displacement curves of the springs

Figure 2. Boundary conditions to verify the displa...

  Figure 2. Boundary conditions to verify the displaceability of teeth (a) and analyze the distribution of occlusal forces (b). Arrows: loads, triangles: restricted nodes, zigzags: springs

Figure 1. Finite element models (model-I and model...

  Figure 1. Finite element models (model-I and model-T). The tooth roots and the implant bodies are displayed with permeability

Table 2 Size of each gap

Occlusal adjustment (model) ___ ___ ___ ___ 4 5 6 7 Adj40N (model-T) 25.0 26.0 13.0 12.0 Adj200N (model-T) 30.0 37.0 23.5 24.0 Adj40N (model-I) 39.4 41.0 42.8 43.5 Adj200N (model-I) 70.9 75.4 79.9 81.6

Table 1 Material properties

Materials Modulus of elasticity (MPa) Poisson ratio Enamel 80,000 0.3 Dentin 17,600 0.25 Inplant (titanium) 117,000 0.32 Superstructure (gold alloy) 94,000 0.3 Cortical bone 14,000 0.3 Cancellous bone 7,900 0.3

Discussion : Effect of bite force in occlusal adju...

Since it was far larger than that of the teeth and implants (Fig. 3), the TMJs and ramus of the mandible were displaced upward and the most posterior implants became fulcrums of the rotation of the mandible. On the other hand, posterior implants were considered to be separated from opposing teeth and implants when the load was less than that exerted during occlusal adjustment. However, becau...

Discussion : Effect of bite force in occlusal adju...

Thus, the “occlusal adjustment” performed on the FE models in this study was not a clinical procedure itself but a procedure to set the models in the state of the ICP under various occlusal loads. This problem can be clarified by the definition of the ICP itself. Although load and deformation of the bone, joints, periodontal ligaments, and teeth in the ICP depend on the amount of the oc...

Discussion : Effect of bite force in occlusal adju...

Discussion FE models The FE models in this study were based on those reported by Kasai et al. The material properties of the soft tissues such as the PDL and the TMJ, which were mainly deformed in the analysis, were considered to be crucial, because the aim of this study was to investigate the distribution of occlusal forces on the teeth, implants, and TMJs. In Figs. 3 and ...

Results : Effect of bite force in occlusal adjustm...

Under Load200N, 20.3 % of the occlusal force was distributed at the molar site implants and 14.0 % of the occlusal force was distributed at the premolar site implants. The POF in the TMJ was larger than that in model-N. Under Load800N, the POF at the molar site implants was 36.3 %. However, almost no occlusal force occurred at the premolar site implants and anterior teeth. The POF in the TMJ wa...

Results : Effect of bite force in occlusal adjustm...

Results Displaceability of teeth The load-displacement curve of the left canine under vertical load indicated two-phase displacement as shown in Fig. 7. Model-T The results of model-T are shown in Fig. 8. Adj40N resulted in the concentration of approximately 25 % of the occlusal force at the most posteriorly located implant on each side. In other words, about half of the total occlusal force...

Methods : Effect of bite force in occlusal adjustm...

Loading conditions The loading conditions assumed intercuspal clenching. On the assumption that occlusal force was generated by the contractile force of four bilateral masticatory muscles, the masseter, temporalis, mesial, and lateral pterygoid muscles, the loading points and the directions of the loads were determined based on the report by Korioth and Hannam and anatomical findi...

Methods : Effect of bite force in occlusal adjustm...

Boundary conditions of the model and simulation of occlusal adjustment The boundary conditions used to verify the displaceability of teeth and analyze the distribution of occlusal forces are shown in Fig. 2a, b, respectively. In the former model, a vertical load was applied to the left canine with the restriction of nodes on the bottom of the mandible (Fig. 2a). FE analysis was pe...

Methods : Effect of bite force in occlusal adjustm...

Methods Finite element model Three-dimensional finite element (FE) models were based on those reported by Kasai et al. and consisted of a mandible, natural teeth with periodontal ligaments, and titanium implants with superstructures. All elements were homogenous and isotropic. In the models, eight implants replaced all of the premolars and molars (Fig. 1). The mass/volume and ...

Background : Effect of bite force in occlusal adju...

Background Dental implants have been widely used to restore or maintain occlusion, function, and esthetics and are particularly effective for partially edentulous jaws. However, the difference of the displaceability of the implants and natural teeth with periodontal ligaments (PDLs) may cause a problem in an arch that includes both implants and teeth. There is controversy about ...

Effect of bite force in occlusal adjustment of den...

Effect of bite force in occlusal adjustment of dental implants on the distribution of occlusal pressure: comparison among three bite forces in occlusal adjustment   Abstract Background The purpose of this study was to investigate the influence of occlusal forces (the contractile force of masticatory muscles) exerted during occlusal adjustment on the distribution of the forces among teeth, i...

Figure 5. Proportion of the occlusal contact area ...

  Figure 5. Proportion of the occlusal contact area and occlusal load of the whole molar region accounted for by the implant prosthesis and by the contralateral tooth

Figure 4. Comparison of the first molar-eliminated...

Figure 4. Comparison of the first molar-eliminated occlusal contact area and load between the implant side molar region and contralateral side molar region

Figure 3. Comparison of the occlusal contact area ...

Figure 3. Comparison of the occlusal contact area and occlusal load between the implant side molar region and contralateral side molar region

Figure 2. Comparison of occlusal contact area and ...

  Figure 2. Comparison of occlusal contact area and occlusal load between implant and contralateral tooth

Figure 1. Comparison of the occlusal contact area ...

Figure 1. Comparison of the occlusal contact area between Occluzer and BiteEye

Table 8 Two-way ANOVA of the proportion of occlusa...

Table 8 Two-way ANOVA of the proportion of occlusal load and contact area for implants and first molars based on molar area   Source Sum of square df Mean square F value P value Occlusal load              Occluzer Implant or natural tooth 585.390 1 585.390 9.870 0.014 MVC 53.901 3 53.901 1.768 0.220 Interaction 46.872 3 46.872 3.79...

Table 6 Two-way ANOVA of the occlusal contact area...

Table 6 Two-way ANOVA of the occlusal contact area of the implant side molar region and contralateral side molar region excluding the first molar     Source Sum of square df Mean square F value P value Occluzer Implant side and contralateral side 2.177 1 2.177 0.383 0.165 MVC 90.753 3 30.251 25.800 0.553 Interaction 9.011 3 3.004 2.209 0.113 ...

Table 5 Two-way ANOVA of occlusal load of the impl...

Table 5 Two-way ANOVA of occlusal load of the implant side molar region and contralateral side molar region Source Sum of square df Mean square F value P value Implant side and contralateral side 8578.099 1 8578.099 1.354 0.278 MVC 193,888.518 3 64,629.506 36.593 0.000 Interaction 30,575.358 3 4016.245 3.153 0.430

Table 4 Two-way ANOVA of the occlusal contact area...

Table 4 Two-way ANOVA of the occlusal contact area of the implant side molar region and contralateral side molar region     Source Sum of square df Mean square F value P value Occluzer Implant side and contralateral side 24.453 1 24.453 2.334 0.165 MVC 159.749 3 53.253 26.918 0.000 Interaction 16.135 3 5.378 3.786 0.024 BiteEye Implant side ...

Table 3 Two-way ANOVA of occlusal load of implant ...

Table 3 Two-way ANOVA of occlusal load of implant prosthesis and contralateral tooth   Source Sum of square df Mean square F value P value Implant or natural tooth 8732.252 1 8732.252 13.299 0.007 MVC 14,619.565 3 4872.855 16.724 0.001 Interaction 2200.789 3 733.596 8.442 0.001

Table 2 Two-way ANOVA of the occlusal contact area...

  Source Sum of square df Mean square F value P value Occluzer Implant or natural tooth 1941.060 1 1941.060 1.074 0.333 MVC 424.098 3 141.336 1.958 0.147 Interaction 262.581 3 87.527 1.345 0.283 BiteEye Implant or natural tooth 28.022 1 28.022 6.892 0.030 MVC 3.374 2 1.687 1.927 0.178 Interaction 0.916 2 0.458 0.827 0.4...

Table 1 Site of implants

No. Sex Age Implant system Implant site 1 F 35 Straumann Right 2 F 39 Brånemark Left 3 F 47 Brånemark Left 4 F 49 Brånemark Left 5 M 43 Straumann Right 6 M 46 Straumann Right 7 M 69 Straumann Right 8 M 48 Brånemark Left 9 M 67 Brånemark Right

Discussion : Occlusal status of implant superstruc...

Measurement of occlusal contact area of implant prosthesis Dental Prescale has a thickness of approximately 100 μm, whereas Blue Silicone has less thickness and is therefore likely to give more accurate measurements of the occlusal contact area. In addition, when the occlusal contact areas of implant prostheses and their contralateral teeth were compared, the occlusal contact area of the c...

Discussion : Occlusal status of implant superstruc...

Measurement of occlusal contact area of implant prosthesis Dental Prescale has a thickness of approximately 100 μm, whereas Blue Silicone has less thickness and is therefore likely to give more accurate measurements of the occlusal contact area. In addition, when the occlusal contact areas of implant prostheses and their contralateral teeth were compared, the occlusal conta...

Discussion : Occlusal status of implant superstruc...

  Measurement of occlusal load Occlusal load was measured with Dental Prescale and analyzed with Occluzer. The Dental Prescale system allows occlusal contact pressure to be measured quickly and easily across the dentition, and it is of enormous clinical utility because its accuracy and reproducibility in the molar region have been confirmed. The technique using this sequence and also the ...

Discussion : Occlusal status of implant superstruc...

  Discussion Subjects and dentition Males outnumbered females in the present study, but there have been no reports of differences in mean occlusal load between males and females in the 50–54 age group. While there have been reports that in healthy, dentulous subjects, the total occlusal force in the molar region on one side is approximately 400 N at maximum clenching st...

Results : Occlusal status of implant superstructur...

Comparison of proportion of occlusal contact area and occlusal load on the molar region accounted for by prosthetic implant and contralateral tooth With both BiteEye and Occluzer, the proportion of the occlusal contact area on the molar region overall accounted for by the prosthetic implant was less than the proportion accounted for by the contralateral natural tooth, and ANOVA showed this differ...

Results : Occlusal status of implant superstructur...

    Comparison of implant side and contralateral side molar regions Comparison of occlusal contact area in the molar region The occlusal contact area in the molar region on the implant and contralateral sides increased with clenching strength and, at clenching intensity of 60 % MVC or above, was less on the implant side molar region (Fig. 3). ANOVA results (Table 4) showed no...

Results : Occlusal status of implant superstructur...

  Comparison of occlusal contact areas evaluated using Occluzer and BiteEye Occlusal contact area values obtained with BiteEye and Occluzer at clenching intensities from 20 to 100 % MVC were compared (Fig. 1). At different clenching intensities, the contact area values of BiteEye with silicone thickness of 10 μm (BE 10 μm) were the most si...

Methods : Occlusal status of implant superstructur...

Analysis of the results from Occluzer and BiteEye The following calculations were performed: Comparison of Occluzer and BiteEye in the occlusal contact area Comparison of the occlusal contact area and occlusal load between the implant and same number of natural teeth on the contralateral side Comparison of the occlusal contact area and occlusal load between molar area...

Methods : Occlusal status of implant superstructur...

Measurement of occlusal contact area using BiteEye A material for checking accuracy of fit (Blue Silicone®; GC, Tokyo, Japan) was used to examine the occlusal contact in the intercuspal position. The occlusal contact area was measured once at each clenching strength (20, 40, and 60 % MVC) using visual feedback. Subject posture was the same as during Prescale measurement....

Methods : Occlusal status of implant superstructur...

Electromyograph attachment Masseter muscle activity was measured using an electromyograph (PowerLab; ADInstruments, Nagoya, Japan). Silver disk electrodes of 10 mm in diameter with bipolar leads (Duotrode; Morita Corp., Osaka, Japan) were adhered on both sides of the central part of the masseter muscle. The distance between electrodes was 21 mm, and the electrodes were pl...

Methods : Occlusal status of implant superstructur...

Methods Subjects and dentition Subjects were nine outpatients (5 male, 4 female) attending Showa University Dental Hospital, aged 35–69 years (mean age, 49 ± 12 years) (Table 1). All subjects were cases of single implants placed at the mandibular first molar deficit, on the day of implant prosthesis setting and occlusal adjustment. The criteria for subject selection were no inflammatory...

Background : Occlusal status of implant superstruc...

Background Implants maintain osseointegration with the inside of the bone over long periods of time, and mechanical factors are important for retaining function. Particularly, when natural teeth and implants are present together, differences in tissue displaceability when they are subjected to occlusal force may cause dynamic imbalance from strong to weak clenchi...

Occlusal status of implant superstructures at mand...

Abstract Background Occlusal contact on the implant superstructures is important for successful treatment. The purpose of this study was to investigate the occlusal contact of single implant superstructures at the mandibular first molar immediately after seating from weak to strong clenching. Methods Subjects were nine patients who had just been fitted with an implant prosthesis in the mandi...

Figure 9. a Mandibular implant-fixed prosthesis i...

  Figure 9. a Mandibular implant-fixed prosthesis inserted into the mouth.

Figure 8. Periapical radiographs of the implants

  Figure 8. Periapical radiographs of the implants. a Postoperative, 1 year. b Postoperative, 16 years

Figure 7. a Intraoral photograph. b Gold Dolder...

  Figure 7. a Intraoral photograph. b Gold Dolder bar and screws; marked wear of a prosthetic screw (arrow)

Figure 6. a Mandibular implant-supported overdent...

Figure 6. a Mandibular implant-supported overdenture inserted into the mouth. b Panoramic radiograph after insertion of the prosthesis

Figure 5. Preoperative intraoral photograph of imp...


Figure 3. Photomicrographs of the biopsy specimen

  Figure 3. Photomicrographs of the biopsy specimen showing the intermingling of (a), (b), and (c). a Moderately differentiated epidermoid tumor cells with a duct-like structure (hematoxylin and eosin [H&E], original magnification × 100). b Intermediate cells (H&E, original magnification × 100). c Clear cells (H&E, original magnification × 100)

Figure 4. Intraoperative photograph of resection o...

  Figure 4. a Intraoperative photograph of resection of the alveolar ridge and bilateral upper neck dissection. b Transplantation of a lateral tongue flap to cover the alveolar ridge defect. c Surgical specimen

Figure 2. Panoramic radiograph showing notable alv...

  Figure 2. Panoramic radiograph showing notable alveolar bone resorption in the left mandibular premolar region and slight resorption in the right mandibular canine region (arrows)

Figure 1. Intraoral photograph

Figure 1. Intraoral photograph showing diffuse tumor formation on the alveolar gingiva (arrows)  

Conclusion : Dental implant treatment in a young w...

We inserted an implant-supported overdenture on a gold bar retainer splinting four implants. However, the patient was not satisfied with this prosthesis because of the mucosal pain and discomfort that developed over time. In such cases, prosthetic loading of atrophic mucosa is often not well tolerated. As such, we proposed replacement with an implant-fixed prosthesis. Initially, the patient ...

Conclusion : Dental implant treatment in a young w...

Conclusions Prosthetic rehabilitation of edentulous patients after surgical management of oral cancer is difficult and therefore often avoided. However, adequate prosthetic rehabilitation is a pivotal factor for patients to regain oral function. In terms of the masticatory rehabilitation of these patients, the application of a removable prosthesis unsupported by implants may be difficult or...

Case presentation : Dental implant treatment in a ...

However, she was not satisfied with the prosthesis; she experienced denture discomfort and developed a decubital ulcer in the tongue flap area, and she gradually ceased use of the denture. The patient was followed for more than 10 years on a regular basis to examine recurrence or metastasis of the gingival carcinoma. Mild erythema and swelling of the mandibular and implant-surrounding mucosa secon...

Case presentation : Dental implant treatment in a ...

Case presentation A 16-year-old female patient developed slight tenderness of the gingiva in the left mandibular premolar region, and her dentist referred her to our clinic in April 1992. Oral examination showed erythematous granular swellings that bled easily on the alveolar gingiva involving the area extending from the right second premolar to the left second molar (Fig. 1). The lesion showed...

Background : Dental implant treatment in a young w...

Background Surgical treatment of oral cancer may lead to significant disability, including facial deformity, loss of hard and soft tissue, and impaired function of speech, swallowing, and mastication. Bone resection because of surgical treatment of a large mandibular tumor can cause long-term defects. Rehabilitation with a removable prosthesis can be difficult or impossible due to the distorted...

Dental implant treatment in a young woman

Dental implant treatment in a young woman after marginal mandibulectomy for treatment of mandibular gingival carcinoma: a case report Abstract Dental implants play an important role in postoperative rehabilitation after surgical treatment of oral cancer through the provision of prosthetic tooth replacement. Two major implant prosthesis designs are available: fixed implant-supported prostheses ...

Figure 6. SEM picture of implant with external hex...

  Figure 6. SEM picture of implant with external hexagonal connection

Figure 5. SEM picture of CAMLOG implant after tors...

Figure 5. SEM picture of CAMLOG implant after torsion test Figure 5. SEM picture of CAMLOG implant after torsion test

Figure 4. The mean value of torsional yield streng...

  Figure 4. The mean value of torsional yield strength

Figure 3. The mean value of maximum fracture torqu...

  Figure 3. The mean value of maximum fracture torque strength

Figure 1. Torsion testing device

Figure 1. Torsion testing device

Discussion : The fracture strength by a torsion te...

For comparison between the mechanical strength of CP-Ti screw implants with internal tube-in-tube implant-abutment connections and that of external hexagonal-type connections, all abutments and CP-Ti implants with external hexagonal-type connections were heavily damaged or destroyed in all phases of loading. A typical fracture curve for CP-Ti implants with external connections is shown. The propor...

Discussion : The fracture strength by a torsion te...

Discussion During the physiological function of chewing, or the non-physiological function of bruxism, compressive, bending, and torsional stresses are generated in teeth or prosthetics. These stress will cause the abutment screw loosening or fracture, fracture of the abutment, fracture of the implant, and the implant/abutment connection. The extent of the damage is influenced by the design o...

Methods : The fracture strength by a torsion test ...

Methods Thirty titanium screw implants of five different diameters (3.3, 3.8, 4.3, 5.0, and 6.0 mm) with tube-in-tube implant-abutment connections (CAMLOG Biotechnologies, Wimsheim, Germany) were used as test specimens. Implants of each size were connected to abutments, and abutment screws were tightened to 20 N · cm using a digital torque meter (Hios HDM-5; Hios Inc, Chiba...

Background : The fracture strength by a torsion te...

Background A single-tooth osseointegrated implant is composed of an implant body, an abutment, an abutment screw, and an artificial crown. The implant and abutment are typically connected by an abutment screw. The degree of mechanical integrity at the implant-abutment interface depends on screw preload, abutment connection design, the fitness of all components, and dynamic loading conditions. F...

The fracture strength by a torsion test at the imp...

Abstract Background Fractured connections between implants and implant abutments or abutment screws are frequently encountered in a clinical setting. The purpose of this study was to investigate fracture strength using a torsion test at the interface between the implant and the abutment. Methods Thirty screw-type implant with diameters of 3.3, 3.8, 4.3, 5.0, and 6.0 mm were submitted to a t...

Figure 21. A dental class I occlusion was establis...

  Figure 21. A dental class I occlusion was established only on the right side (lateral aspect)

Figure 20. The left side could not be restored to ...

  Figure 20. The left side could not be restored to an ideal class I relationship from the original class II due to the pontic prosthesis

Figure 19. A full-mouth frontal aspect

  Figure 19. A full-mouth frontal aspect

Figure 18. OPT after prosthodontic finalization

  Figure 18. OPT after prosthodontic finalization

Figure 17. Implants were used for implant-retained...

  Figure 17. Implants were used for implant-retained prostheses (abutment-cemented crowns), and a three-unit fixed partial denture pontic (crowns 25–27) was placed  

Figure 16. After orthodontic treatment was complet...

  Figure 16. After orthodontic treatment was completed, the prosthodontic phase took place

Figure 15. All implants received immediate healing...

  Figure 15. All implants received immediate healing screws

Figure 14. Implants placement after site preparati...

  Figure 14. Implants placement after site preparation  

Figure 13. Implant site preparation: OP5, IM2, OT4...

  Figure 13. Implant site preparation: OP5, IM2, OT4, and IM3 (correctly in sequence)

Figure 12. The total width flap was sutured

  Figure 12. The total width flap was sutured

Figure 11. A mesiobuccal root surface exposure of ...

  Figure 11. A mesiobuccal root surface exposure of element 16 required bone regeneration through Bio Oss and bone chip application

Figure 10. A triangular-shaped corticotomy was per...

  Figure 10. A triangular-shaped corticotomy was performed with inserts OT7 0.55 mm and OT7 special 0.35 mm to accelerate orthodontic tooth movements

Figure 9. A microsurgical corticotomy was mandator...

  Figure 9. A microsurgical corticotomy was mandatory to assist orthodontic tipping and intrusion of elements 16 and 17  

Figure 8. Orthodontic bracket placement: left side...

  Figure 8. Orthodontic bracket placement: left side view  

Figure 7. Ortodontic bracket placement: right side...

    Figure 7. Ortodontic bracket placement: right side view

Figure 6. Orthodontic bracket placement: frontal v...

  Figure 6. Orthodontic bracket placement: frontal view

Figure 5. The panoramic radiography and cephalomet...

    Figure 5. The panoramic radiography and cephalometric analysis revealed a partially edentulous mandible

Figure 4. The panoramic radiography and cephalomet...

  Figure 4. The panoramic radiography and cephalometric analysis revealed a partially edentulous mandible

Figure 3. Some metal ceramic crowns in the upper l...

Figure 3. Some metal ceramic crowns in the upper left maxillary arch with a very poor esthetic appearance

Figure 2. Initial lateral intraoral aspect

Figure 2. Initial lateral intraoral aspect

Figure 1. Initial frontal intraoral aspect

Figure 1. Initial frontal intraoral aspect

Discussion : A piezo surgery with corticotomies an...

A number of reports have indicated that orthodontic treatment can improve the periodontal situation in patients with pathologic migration by providing good function and improved esthetics after realignment. It is generally recommended that orthodontic treatment should be preceded by periodontal therapy. In fact, orthodontic treatment when there is an inflammation/periodontal...

Discussion : A piezo surgery with corticotomies an...

Discussion The management of an anterior deep bite requires adequate treatment planning, especially if the clinical condition is associated with posterior DVO (vertical occlusion dimension) reduction due to multiple missing teeth. A multidisciplinary planning approach, including orthodontics, oral and periodontic surgery, and restorative dentistry, has an important role in t...

A piezo surgery with corticotomies and implant pla...

This was a preliminary stage before the first surgical corticotomy (performed with a piezo device). A microsurgical corticotomy was mandatory to assist orthodontic tipping and intrusion of elements 16 and 17. This surgical procedure was performed by a piezo approach (Fig. 9). A total width flap was elevated to make the cortical subapical and longitudinal bone cut possible. The ...

A piezo surgery with corticotomies and implant pla...

Case presentation Diagnosis and etiology A young female patient was referred to our dental clinic to resolve a malocclusion disorder due to missing teeth. She was unsatisfied with the functional aspect of her dentition. She had a second upper right molar very damaged by caries (17) (Figs. 1 and 2); it was also extruded due to missing antagonist teeth (I and II l...

A piezo surgery with corticotomies and implant pla...

A piezo surgery with corticotomies and implant placement as part of a multidisciplinary approach to treat malocclusion disorder in an adult patient: clinical report Abstract This clinical report illustrates a multidisciplinary approach for the rehabilitation of a young adult patient affected by a bilateral edentulous space and an anterior deep bite. The patient required orthodontics and surgic...

Figure 3. Erythroid, granulocytic, monocytic and l...

Figure 3. Erythroid, granulocytic, monocytic and lymphocytic series are illustrated, as well as megakaryocytes (hematoxylin and eosin, original magnification ×400)

Figure 2. Normal hematopoietic cells, fat cells an...

Figure 2. Normal hematopoietic cells, fat cells and bone trabeculae (hematoxylin and eosin, original magnification ×200)

Figure 1. The periapical radiograph revealed the p...

  Figure 1. The periapical radiograph revealed the presence of an extensive and poorly circumscribed osteoporotic area around the proximal implant

Focal osteoporotic bone marrow defect involving de...

Only few cases of the focal osteoporotic bone marrow defect associated with dental implants has been described in the English literature. Sençimen et al. (2011) reported a clinical case in which the focal osteoporotic bone marrow defect occurred 2 years postoperatively apical to a dental implant in posterior mandible region and the diagnosis was established based on the combination of clini...

Focal osteoporotic bone marrow defect involving de...

  Case presentation An 84-year-old white woman was referred to private dental clinic for an implant rehabilitation treatment. Intraoral examination revealed healthy mucosa and there was not any sign of infection. Her past medical history was unremarkable. The radiography of the molar region showed with a quite ill-defined radiolucent area presenting irregular borders associated to dental impl...

Focal osteoporotic bone marrow defect involving de...

Abstract In oral implantology, the most serious complications occur intraoperatively or within a short period. We describe an unusual case of focal osteoporotic bone marrow defect involving dental implant in the posterior mandibular region of the adult woman. Despite the fact that this condition requires no treatment, it could lead to the displacement of the dental implant. Additionally, th...

Figure 5. Torque-time curves of the MK3 and MK4

  Figure 5. Torque-time curves of the MK3 and MK4. a Insertion torque. b Removal torque

Figure 4. Torque-time curves of the TE. a Insertio...

Figure 4. Torque-time curves of the TE. a Insertion torque. b Removal torque

Figure 3. Torque-time curves of the BL. a Inserti...

  Figure 3. Torque-time curves of the BL. a Insertion torque. b Removal torque  

Figure 2. Torque-time curves of the ST. a Insert...

  Figure 2. Torque-time curves of the ST. a Insertion torque. b Removal torque

Figure 1. Compressed longitudinally to one third f...

Figure 1. Compressed longitudinally to one third for characteristics of implant design. ST Straumann standard implant, MK3 Nobel Biocare MKIII, BL Straumann bone level implant, TE Straumann tapered effect implant, MK4 Nobel Biocare MKIV. Outer surface of implant (solid line). Inner surface of implant (dotted line) Figure 1. Compressed longitudinally to one third for characteristics of implant d...

Table 3 Torque rise rate of the each area (N ·...

  Initial area Parallel area Tapered area Platform area ST6 1.42 ± 0.43 0.31 ± 0.14 – – ST8 3.57 ± 1.62 0.35 ± 0.09 – – ST10 2.49 ± 0.81 0.45 ± 0.05 – – BL8 2.16 ± 0.21 0.50 ± 0.08 2.32 ± 0.52 – BL10 1.96 ± 0.49 0.35+0.04 2.45+0.23 – BL12 1.82 ± 0.27 0.33 ±...

Table 2 Insertion torque value and removal torque ...

Code Insertion torque Removal torque Effective thread length (ETL) (N · cm) (N · cm) (×π mm) ST6 6.19 ± 0.716 5.95 ± 0.718 11.53 ST8 8.06 ± 1.038 9.09 ± 1.093 15.11 ST10 13.13 ± 1.763 12.37 ± 1.746 21.48 BL8 17.67 ± 1.290 16.67 ± 2.140 20.88 BL10 23.56 ± 1.628 21.99 ± 1.530 31....

Table 1 The type of the implant used for experimen...

System Length Pitch Lead Code Manufacturer (mm) (mm) (mm) Standard RN 6, 8, 10 1.2 1.2 ST Straumann Bone Level RC 8, 10, 12 0.8 0.8 BL Straumann Tapered Effect RN 10 0.8 0.8 TE Straumann Brånemark MKIII 10 0.6 1.2 MK3 Nobel Biocare Brånemark MKIV 10 0.6 1.2 MK4 Nobel Biocare

Reference : Effect of implant design on primary (...

Abbreviations BL: Bone Level RC IT: insertion torque value MK3: Brånemark MKIII MK4: Brånemark MKIV RT: removal torque value ST: Standard RN TE: Tapered Effect RN References Friberg B, Sennerby L, Roos J, Johansson P, Strid CG, Lekholm U. Evaluation of bone density using cutting resistance measurements and microradiography. An...

Discussion : Effect of implant design on primary ...

Influence of cortical bone The reason why a simulation test for only cancellous bone without cortical bone was performed in the present study has already been described. It was reported that bone density and the ratio of cortical bone and cancellous bone have influence on the primary stability of an implant and that higher primary stability is achieved with thread, even at the slightest lev...

Discussion : Effect of implant design on primary ...

Although the removal torque curves measured in the present study had similar shapes to one another, they were divided into two groups upon detailed observation, comprising a group of ST with parallel only, and a group of BL, TE, MK3, and MK4 having tapers and platforms. Since the thread contacts the artificial bone sequentially at the time of insertion, the torque curves showed the character...

Discussion : Effect of implant design on primary ...

This indicates that the friction at the time of rotating and pressing is greater than that at the time of rotating and cutting the bones with a tap and is a reasonable result. In the parallel area, the torque curve was a line with a moderate gradient, and the torque rise rate obtained from the gradient of the line was 0.36 N · cm/s. From this, it is estimated that the torque increase w...

Discussion : Effect of implant design on primary ...

Discussion Insertion torque curve In 2000, O’Sullivan reported torque curves for a prosthetic implant for the first time, and evaluated the characteristics of the tapered type by torque curves obtained by inserting five kinds of implants into the maxillary bone of unembalmed human cadavers. In a subsequent review, Meredith cited six kinds of torque curves when the final osteotomy diamete...

Results : Effect of implant design on primary (2)

For the TE, the lower part of the implant was parallel and the lateral surface and axial surface had the same taper in the cervical region. TE10 in Fig. 4a showed a torque curve with a similar form to BL10 in Fig. 3 and had three kinds of areas. The torque curves for MK3 and MK4 in Fig. 4a had an area in which the torque finally rose suddenly after reaching its critical point and became moderate...

Results : Effect of implant design on primary (1)

Results Insertion torque The insertion torque curve was divided into four regions. The first was the region where the torque rose suddenly immediately after insertion, which was seen in all implant bodies (shown as ① in the figure, and hereinafter called the initial area). The second was the region where the torque rose linearly with a moderate gradient, which was seen in all implant bodie...

Methods : Effect of implant design on primary stab...

Methods Implants The type of implant used for the experiments and the characteristics of its design are shown in Table 1 and Fig. 1, respectively. Figure 1 shows that the implant is compressed longitudinally to one third. The outer surface of the implant is indicated with a solid line, and the inner surface of the implant is indicated with a dotted line. Preparation of an implant socket in ...

Background : Effect of implant design on primary s...

Background Primary stability following implant placement is an essential condition for osseointegration. The primary stability is affected by the implant design, including surface-modifying or implant cavity-forming techniques, as well as by the bone quantity and bone density of the patient. In recent years, the interest of implant manufacturers and clinicians has shifted to the acquisition of ...

Effect of implant design on primary stability usin...

Abstract Background Primary stability following implant placement is essential for osseointegration and is affected by both implant design and bone density. The aim of this study was to compare the relationships between torque-time curves and implant designs in a poor bone quality model. Methods Nine implant designs, with five implants in each category, were compared. A total of 90 implants ...

Figure 4. Sublingual artery originating from an an...

  Figure 4. Sublingual artery originating from an anastomotic branch of the lingual and submental arteries: h submental artery, i hypoglossal artery, j lingual artery, and k anastomosis of the lingual and submental arteries

Figure 3. Submental artery as the source of the su...

  Figure 3. Submental artery as the source of the sublingual artery entering the MMLF: e submental artery, f inferior border of the mandible, and g facial artery  

Figure 2. Lingual artery as the origin of the subl...

  Figure 2. Lingual artery as the origin of the sublingual artery entering the MMLF: a external carotid artery, b lingual artery, c hypoglossal nerve, d right and left sublingual arteries originating from the ipsilateral lingual arteries and e inferior border of the mandible

Figure 1. Distribution of cadavers according to so...

Figure 1. Distribution of cadavers according to source of artery entering the MMLF (n = 34) Figure 1. Distribution of cadavers according to source of artery entering the MMLF (n = 34)

Discussion : Arterial blood supply variation in th...

The sublingual and submental arteries normally anastomose through their muscular mylohyoid branches. Loukas et al. only identified anastomotic patterns between sublingual and submental arteries in 40 % of the dissected cadavers, with no case where the two terminate as a single sublingual artery. We found three (8.9 %) cases of an anastomotic branch of the submental and lingual artery formi...

Discussion : Arterial blood supply variation in th...

The MMLF is a consistent structure through which the sublingual artery enters the mandible. Perforation of the lingual plate by an implant drill poses a high risk of trauma to this vessel especially when the sublingual fossa is very pronounced because this vessel courses closely to the gland and fossa. When this artery is of a significant size, it is possible for 420 mL of blood to escape in...

Results : Arterial blood supply variation in the a...

Results A total of 34 human cadavers were dissected in this study of which 30 (88.2 %) were males and 4 (11.8 %) were females (male/female, 15:2) aged between 25 and 40 years. The linear distance between the MMLF and the inferior border of the mandible ranged from 11.03 to 19.62 mm (mean = 15.58 mm ± 2.12 SD). The mesio-buccal thickness of the mandible at the level of the MMLF ra...

Methods : Arterial blood supply variation in the a...

Methods This was a cadaveric dissection study involving 34 human adult cadavers of indigenous Kenyan descent carried out at the Department of Human Anatomy, University of Nairobi. Majority of these cadavers are unclaimed bodies in the city of Nairobi, whose demographics are hardly known. Approval to conduct the study was obtained from the Kenyatta National Hospital/University of Nairobi Ethics,...

Background : Arterial blood supply variation in th...

Background The inter-foraminal region of the human mandible is a common elective area for several dental surgery procedures due to its favourable anatomic conditions. Some of the procedures done in this region include insertion of endosseous dental implants, bone harvesting from the chin, genioplasty in orthognathic surgery and placement of screws during plating in management of facial fracture...

Arterial blood supply variation in the anterior mi...

Abstract Background Inter-foraminal implant placement poses a risk to the sublingual artery as it enters the mandibular midline lingual foramen. Lack of consensus on the source of this artery poses a dilemma to surgeons during management of haemorrhagic episodes. Determination of the exact source of this artery is therefore pivotal. Methods This was a cross-sectional descriptive study involv...

Figure 9. Do you have any requests for dentists wh...

Figure 9. Do you have any requests for dentists who practice implant treatment?

Figure 8. What are the frequently received repair ...

Figure 8. What are the frequently received repair requests for IODs?

Figure 7. Creative steps to prevent veneer fractur...

  Figure 7. Creative steps to prevent veneer fracture and chipping in the molar region

Figure 6. the frequently received repair requests ...

Figure 6. the frequently received repair requests involving implant fixed prostheses

Figure 5. The main fabrication challenges faced

Figure 5. The main fabrication challenges faced

Figure 4. The proportions of attachment types used...

Figure 4. The proportions of attachment types used with IODs

Figure 3. Types of implant fixed prostheses are us...

Figure 3. Types of implant fixed prostheses are used in the posterior region

Figure 2. Types of materials used to make implant ...

Figure 2. Types of materials used to make implant prostheses in the anterior region

Figure 1. The proportions of abutments used with c...

Figure 1. The proportions of abutments used with cement-retained prostheses    

Conclusions: Current status of implant prosthetics...

  This survey served to clarify the current status of implant prosthodontics, issues, and considerations in their fabrication, and the status of prosthetic complications and preventive initiatives, all from a laboratory perspective. Concerning implant treatment, it was concluded that dentists either play the leading role or work in collaboration with technicians, inc...

Result & discussion: Current status of implant pro...

While the literature includes reports of frequent IOD-related prosthetic complications such as attachment-related compromised retention, detachment or fracturing of denture teeth, relining, and attachment damage, this survey showed a somewhat different trend. It can be inferred that these results differ from actual complication trends because they constitute responses to cases sent to ...

Result & discussion: Current status of implant pro...

The questionnaire revealed several creative steps, based on laboratory considerations, being taken to prevent veneer chipping and fractures, a frequent and problematic prosthetic complication (Q12) (Figure 7). Technicians were taking into account metal (including zirconia) coping designs (36.3%), covering only the distal-most part of the molar region with metal (24%), using veneering composi...

Result & discussion: Current status of implant pro...

Looking at repair requests (i.e., complications) involving the superstructures of fixed implant prostheses (Q11) (Figure 6), facing damage and chipping accounted for more than half of all requests (54.5%). Generally speaking, there are many reports that indicate a high incidence of complications related to fixed prostheses involving abutment screw loosening, detachment of cement-retained cro...

Result & discussion: Current status of implant pro...

This number was lower than in any of the other nine countries, and future changes in IOD use in Japan are a topic that remains interesting. 4. Prosthetic complications (Table 4) According to Papaspyridakos et al., indicators such as implant level (the relationship between the implant and bone) and the state of soft tissue around the implant are the most frequently used indices of implant s...

Result & discussion: Current status of implant pro...

There is also a greater possibility of direct (in-mouth) repair of failed veneering materials and greater shock-absorbing potential relative to occlusal force in comparison with porcelain. The trend to adhere resin materials instead of porcelain, from Brånemark and colleagues’ recommendations for acrylic resin as an occlusal surface material in the early 1980s, also cannot be ignored. All...

Result & discussion: Current status of implant pro...

There is a low risk of facing damage and chipping for prostheses in the anterior region. Nonetheless, the questionnaire revealed the unexpected result that indirect composite facing crowns accounted for 21.3% of the total. This may be because there are many indirect composite resins (Estenia, Ceramage, etc.) available in Japan, and crowns and bridges in the anterior region (natural abutment ...

Result & discussion: Current status of implant pro...

Our questionnaire indicated a distribution of 61.4% cement-retained versus 38.6% screw-retained prostheses (Q3), suggesting that cement retention is used more frequently in Japan. Unfortunately, the fabrication-oriented focus of this survey prevented clarification of the types of cement used for cement retention and the breakdown between provisional and definitive cement. Next, ...

Result & discussion: Current status of implant pro...

Dentists play a leading role in 39.3% of the time in implant treatment planning and prosthetic design, and dental technicians are consulted concerning cases and part usage 34.7% of the time, suggesting the approach to implants is driven by prosthetic considerations (by dentists) to some degree. However, because dental technicians indicated that they take the initiative 15% of the time, it is...

Result & discussion: Current status of implant pro...

Results and discussion Out of 120 surveys sent, 74 technicians responded, resulting in a response rate of 61.6%. A summary of the responses is provided in Tables 1, 2, 3, dan 4 dan Gambar 1, 2, 3, 4, 5, 6, 7, 8, dan 9. Because implant treatment (implant prostheses) requires a significant amount of specialized, high-precision laboratory procedures, this area of dental care exhibits slight...

Table 4 Prosthetic complications

Question   Values Q9. What are the main issues generally encountered? Compatibility precision issues 29.6% Aesthetic issues 33.2% Occlusal issues 37.2% Q10. What are the main fabrication challenges faced? Poor implant location and orientation 42.4% Inadequate consideration of occlusion 17.0% Defects and inaccuracies in impression and bite registrat...

Table 3 Implant overdentures (IODs)

Question   Values Q7. The design of the implant overdenture: Decision made according to instructions of dentist 43.2% Work is left to technicians 19.3% Decided upon through consultation with each other 37.5% Q8. What are the proportions of attachment types used with IODs? Bar and clip 35.6% Magnet 30.2% Ball and socket 19.0% Locator 5.2% ...

Table 2 Implant fixed prostheses

Question   Values Q3. The percentages of implant fixed prostheses: Cement-retained 61.4% Screw-retained 38.6% Q4. What are the proportions of abutments used with cement-retained prostheses? CAD/CAM (titanium) 19.7% CAD/CAM (zirconia) 12.1% Custom abutments (UCLA-type abutment + gold alloy) 33.2% Two-piece-type titanium (prepable type) 28.3% ...

Table 1 Conditions characterizing implant laborato...

Question   Values Q1. The years of experience working as a dental technician, and the number of dentists from whom job orders are received.   Mean (SD) 17.0 (6.8) years 36.5(12.4)/Lab. Q2. Who takes the leading role in treatment planning and prosthetic design (initiative with regard to prostheses)? Dentists mainly exercise initiative 39.3% Technicians mai...

Methods : Current status of implant prosthetics in...

Methods This cross-sectional questionnaire survey was performed among the certified dental technicians of JSOI from September to December in 2011. Selected were 120 out of 285 certified dental technicians of JSOI using a random number table and mailing each questionnaire directly to the participant. To facilitate coverage of a broad range of topics, the survey classified content into the follow...

Background : Current status of implant prosthetics...

However, because understanding the status of these complications is based on the results of surveys targeting dentists, information is needed on the situation as seen from the standpoint of implant technicians, to clarify the causes of these complications and the techniques for dealing with them. Issues including inadequate communication between dental technicians and dentists and insufficient ins...

Background : Current status of implant prosthetics...

Background Currently, dental implant treatment is evaluated on the basis not only of restoring masticatory function, but also a variety of other factors, including the implant and superstructure survival rate and psychological impacts. Numerous factors must be taken into account, to offer highly predictable implant treatment, and there is no doubt that prosthetic-related factors such as the typ...

Current status of implant prosthetics in Japan

Abstract Background There are many implant cases in which dental technicians take initiative with regard to the design of implant prostheses, and to a certain extent, this area of care is one in which dentists do not necessarily play the leading role. Moreover, inadequate communication between dental technicians and dentists and insufficient instructions for technicians has been highlighte...

Table 2 Specialized scope of published articles wi...

  Dental Orthopedic Medical Environment Basic Titanium toxicity 82 102 150 252 643 Titanium alloy toxicity 42 30 35 5 37 Titanium implant toxicity 37 56 22 3 74 Titanium implant corrosion 145 63 22 7 220 Titanium allergy 22 26 20 2 15 Yellow nail syndrome – – 250 – 6 Total 328 277 499 269 995

Table 1 Number of articles representing each titan...

  1991–1995 1996–2000 2001–2005 2006–2010 2011–2015 2016–2018 Titanium toxicity 30 58 81 216 432 412 Titanium alloy toxicity 12 17 30 18 40 32 Titanium implant toxicity 8 20 30 26 53 55 Titanium implant corrosion 20 48 59 88 122 120 Titanium allergy 2 5 5 21 22 30 Yellow nail syndrome 22 30 31 39 61 73 ...

Conclusion : General review of titanium toxicity

Conclusion Titanium is used in many fields in addition to being used in dental implants. As the use of titanium increases, concerns over safety are increasing as well. In recent years, studies with regard to titanium toxicity have been on the rise. Although they have mainly been focused on environmental and basic fields, studies are now expanding into the medical field. Thus, there is a need fo...

Discussion : General review of titanium toxicity (...

Alternative methods of implant materials are under investigation for the risk of titanium. Typically, these include zirconia and polyetheretherketone (PEEK) dental implants. These materials are considered to be alternatives to the hypersensitivity of titanium and are aimed at improving esthetics. Currently, zirconia is a clinically applied material for dental implants. There have been many s...

Discussion : General review of titanium toxicity (...

The next issue involves looking at the potential threats of titanium. Titanium is currently used in a wide range of fields. As such, there are many studies with regard to environment safety in the field and basic science. Such titanium is primarily used as titanium oxide nanoparticles. Animal experiments, especially in rodents, are being conducted to study the effects of titanium oxide nanop...

Discussion : General review of titanium toxicity (...

Titanium is known to yield fewer allergic reactions than other metals such as nickel and palladium. However, as mentioned in the "Results" section, titanium allergy symptoms have been reported in some cases. These symptoms can occur systemically with inflammation of the mouth, erythema, etc. Therefore, any history or suspicion of a titanium allergy would be considered prior to dental implan...

Discussion : General review of titanium toxicity (...

The absorbed titanium can accumulate in other organs in the body as shown in the animal and cultured cell experiments. In addition, Feng et al. reported that nanoparticles can pass through the blood-brain barrier (BBB) and may be toxic to the central nervous system (CNS). The testing methods still have limitation and further studies need to be performed, but the neurotoxic nanoparticles incl...

Discussion : General review of titanium toxicity (...

This is defined as a tribosystem which has three interrelated components: tribology (friction, wear, and lubrication), corrosion (material and environmental factors), and biochemistry (interactions between cells and protein). The wear and corrosion in the contacting surface of implant fixture and implant abutment can cause the failure of dental implant system, and the wear debris and metalli...

Discussion : General review of titanium toxicity (...

Discussion Titanium is presently used in a variety of applications including dental implants, orthopedic prostheses, industrial cosmetics, drugs, confections, and paints. Due to its extensive usage, issues related to stability need to be discussed. Titanium dental implants possess many advantages and are now widely used with high rates of success. However, we need to look at the aforementio...

Results : General review of titanium toxicity (13)

There are numerous reports showing the association between titanium and yellow nail syndrome in addition to the above reports. In 2015, Decker et al. reported a case of a 67-year-old female patient who had lost her claws 18 months prior and had changes in bronchitis, sinusitis, and nails within the last 5 years. Inhaled corticosteroids were used for initial continuous cough symptoms but were no...

Results : General review of titanium toxicity (12)

At least 10 of 20 patients were reported to show an improvement in symptoms after 6 months of continuous vitamin E1 administration at 200 IU/day; however, there was a continuous debate regarding the medication details. Efforts to elucidate the pathogenesis of yellow nail syndrome are currently underway. In 2001, D’Alessandro et al. reported that the protein content of pleural effusions was...

Results : General review of titanium toxicity (11)

Titanium-related diseases It has been reported that systemic disease can occur due to titanium. According to a study by Berglund and Carlmark in 2011, titanium can be attributed to the cause of “yellow nail syndrome.” In 30 patients with yellow nail syndrome, energy-dispersive X-ray fluorescence (EDXRF) was used to measure the titanium content in the nails of patients; the titanium content w...

Results : General review of titanium toxicity (10)

All metal prostheses except the implant screw and abutment were removed, and the eczema reaction was reduced to 30%; the symptoms still remained. The removal of the titanium implant screw and abutment in 2014 led to a full recovery. In Korea, allergy condition has also been reported after the installation of titanium implants. In 2012, a 70-year-old woman exhibited a stomatitis that appeared to be...

Results : General review of titanium toxicity (9)

They are the releasing due to the friction between implant and bone surface during installation, the wear during debridement at maintenance visits, and the corrosion. Fretwurst et al. reported the metal particle in peri-implant soft tissue along with M1 macrophages and the increasing in titanium concentration with lymphocytes detection. In association with the metal particle releasing, the damage ...

Results : General review of titanium toxicity (8)

Recently, there are more studies working on the linking of titanium implants and implant complication or failure. Wachi et al. reported that Ti ions may be involved in the deteriorating effects of peri-implant mucositis, which can develop into peri-implantitis accompanied by alveolar bone resorption. Olmedo et al. reported two cases of reactive lesions of peri-implant mucosa associated with titani...

Results : General review of titanium toxicity (7)

Maritini et al. compared implantation of titanium powder plasma-spray-coated titanium screws (TPS-Ti) and fluorohydroxyapatite-coated titanium screws (FHA-Ti). Authors reported the evidence of titanium dispersion inside the medullary spaces when TPS-Ti was implanted, which was the result of friction occurring at the implant surface-host bone interface, leading to loss of integration in the coating...

Results : General review of titanium toxicity (7)

In the presence of both H2O2 and albumin, there was a very much higher rate of metal release from Ti6Al4V compared to the presence of albumin and H2O2 alone. Furthermore, in a recent study, Zhang et al. continuously worked on the synergistic effect of albumin and H2O2 on corrosion of Ti6Al4V in physiological saline with electrochemical method and showed the time-dependent dissolution of Ti6Al4V. ...

Results : General review of titanium toxicity (6)

In 1993, Haynes et al. performed experiments using titanium-aluminum-vanadium (Ti-Al-V) and cobalt-chromium (Co-Cr) particles of similar size range and concentration similar to those found in failed hip prostheses. In the abdominal macrophage experiments of rats, Co-Cr yielded a high toxic response while Ti-Al-V increased the release of inflammation-inducing mediators such as prostaglandin E2, int...

Results : General review of titanium toxicity (5)

The interaction between TiO2-NP and inflammatory cytokines, including CXCL8, a clinically relevant pro-inflammatory chemokine, was also investigated by Batt et al.. The authors found that the TiO2-NP could preferentially adsorb CXCL8 (and IFN-γ), which leads to the disruption of neutrophil chemotaxis and modifies local inflammatory mediator concentration and might result in hampered inflammatory ...

Results : General review of titanium toxicity (4)

Recently, Kim et al. reported an in vitro experiment regarding the expression of mucin genes in human airway epithelial cells. The authors confirmed that TiO2-NP initiated the TLR4-dependent pathway, leading to the MUC5B overproduction, which relates to the inflammatory response in human airway. In Suarez-Lopez del Amo et al. experiment, the TiO2 particles derived following implantation were colle...

Results : General review of titanium toxicity (3)

Valentini et al. investigated the toxicity of TiO2-NP to the cortical neuron cultures and in the brain of rats, reported the clear impact of TiO2-NP on the neuronal cells and rat brain, and indicated the new evidences of TiO2-NP toxicity in CNS. While there have been reports of titanium toxicity in animal models, Fabian et al. and Warheit et al. reported that the risk of titanium toxicity was no...

Results : General review of titanium toxicity (2)

The toxicity of TiO2 (titanium dioxide) nanoparticles (TiO2-NP) in rodents has been reported. Many authors studied the serum biochemical parameters, pathology changes, and the biodistribution of TiO2-NP in the liver, kidneys, lung, spleen, and brain tissue by facilitating a variety of methods including blood biomarker assays, histopathological examination, etc. The dependence of experiment results...

Results : General review of titanium toxicity (1)

Results Extensive data was searched as mentioned in the research methods. According to the data analysis, the number of papers from 2011 to 2015 was the highest at 730; the research shows a trend of rapid increase in recent years with the large number of papers from 2016 to 2018. In the author’s field of specialization, 995 fields of basic science were the most studied; fields within environm...

Methods : General review of titanium toxicity

Methods Focus question “What is the general overview of the risks and stability associated with titanium materials?” Literature search This review was prepared using data collected from until November 2018 through a keyword online search using MEDLINE (PubMed), Embase, Cochrane Library, and Google Scholar. Additional data were gathered for the necessary detailed parts using keywords incl...

Background : General review of titanium toxicity

Background Titanium is one of the most widely used materials for dental implants due to its mechanical strength, biocompatibility, and a long history of use. Current titanium dental implants possess a high success rate; however, failures are still being reported. Cause of these implant failures can be poor oral hygiene, uncontrolled deposition of plaque, and calculus around the implant which ca...

General review of titanium toxicity

Abstract Background Titanium is a commonly used inert bio-implant material within the medical and dental fields. Although the use of titanium is thought to be safe with a high success rate, in some cases, there are rare reports of problems caused by titanium. In most of these problematic reports, only individual reports are dominant and comprehensive reporting has not been performed. This comp...

Results : Dental implants and diabetes mellitus (5...

While four studies conclude better implant survival and less peri-implant complications in the well-controlled group, the three others see no difference in implant success even in the poorly controlled patients. The study of Khandelwal treated exclusively patients with poor glycemic control (HbA1c 7.5–11.4 %) and had 98 % implant survival, after 4 months; therefore, he concluded that implant the...

Results : Dental implants and diabetes mellitus (4...

  Diabetes and bone augmentation We identified two prospective studies that evaluated “advanced” implant surgery covering sinus lift procedure and guided bone regeneration. The study of Erdogan consists of type II diabetics moderately and well-controlled (HbA1c 6–7.5 %) with a mean duration of disease of 7.5 years and a healthy control group. Augmentation of the maxilla was performed by g...

Results : Dental implants and diabetes mellitus (3...

The bleeding on probing is more often in the poorly controlled population, but the probing depth is not increased. Diabetes and implant survival Implant survival is an easily defined and measured endpoint for dental implant therapy. Nearly every study reports its implant survival rate. Our literature search identified 18 publications with these data. We divided them into two groups: the first on...

Results : Dental implants and diabetes mellitus (2...

We identified two prospective studies investigating the influence of type II diabetes on osseointegration. They are published by the same author but are independent studies from different years. In both studies, the patients included were stratified by HbA1c levels as well-controlled (HbA1c 6.1–8 %), moderately controlled (HbA1c 8.1–10 %), and poorly controlled (HbA1c ≥10 %). The healthy...

Materials & methods : Dental implants and diabetes...

  Materials and methods The substructure of the systematic review is based on the PRISMA statement. The focused question according to the PICO schema is: “Do diabetic patients with dental implants have a higher complication rate in comparison to healthy controls?” Search strategies The systematic literature search was performed by an independent scientist (Burkhard Kunzendorf). The follow...

Conclusions : Dental implants and diabetes mellitu...

Conclusions The literature included to this review is very heterogeneous concerning the investigated objects, methods, and conclusions. Diabetes is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period. When looking at the complications and side effects resulting from diabetes, it is important to know which type of diabetes the patient suffers from, if...

Results : Dental implants and diabetes mellitus (1...

Results Study selection There are no guidelines existing to the topic of dental implants and diabetes mellitus. A total of 327 potentially relevant titles and abstracts were found by the electronic search and additional evaluation of reference lists. During the first screening, 230 publications were excluded based on the title and keywords. Additionally, 24 titles were excluded based on abstract...

Introduction : Dental implants and diabetes mellit...

Introduction Today, dental implants are one of the restorative methods to replace missing teeth. Improvements in implant design, surface characteristics, and surgical protocols made implants a secure and highly predictable procedure with a mean survival rate of 94.6 % and a mean success rate of 89.7 % after more than 10 years. Implant survival is initially dependent on successful osseointegration...

Dental implants and diabetes mellitus—a systemat...

Abstract Dental implant surgery has developed to a widely used procedure for dental rehabilitation and is a secure and predictable procedure. Local and systemic risk factors can result in higher failure rates. Diabetes mellitus is a chronic disease that goes in with hyperglycemia and causes multifarious side effects. Diabetes as a relative contraindication for implant surgery is controversially...

Table 3 Articles excluded and reasons for exclusio...

Reason for exclusion Investigations Study design (case series or case report) Kim et al. (2017), Hatano et al. (2007) Different grafting technique (lateral sinus lift or transalveolar technique) Jensen et al. (1994), Winter et al. (2002), Toffler et al. (2004), Chappuis et al. (2009), Soltan et al. (2011), Xiao et al. (2011), Cricchio et al. (2011), Scala et al. (2012), Brus...

Table 2 Characteristics of the included investigat...

Author (year) Study design Follow-up (months) N of patients N of implants Smokers Length and diameter (mm) Implant system  Shihab 2017 Retrospective 60 35 70 NA 5–12 × 3.0–5.7 IDI FMD Nucleoss  Ghanem 2014 Retrospective 72 10 10 NA NA NA  Nooh 2013 Prospective 12 56 63 0 4 × 8 4.3 × 10 5 × 8 5 × 10 Nobel Biocare ...

Table 1 Clinical and radiographic complications re...

Clinical complications Radiographic complications Sinusitis Thickening of Schneiderian membrane Nasal bleeding, nasal obstruction, nasal secretion Bone reaction to the implants Headache and pain or tenderness in the region of the sinus Sinus pathology Decreased sense of smell  

Figure 4. Statistical analysis for different varia...

  Figure 4. Statistical analysis for different variables. a Weighted mean survival rate. b Implant survival rate according to degree of penetration. c Analysis of clinical complications. d Analysis of radiographic complications

Figure 3. Graphic representation of group 1 ≤ ...

  Figure 3. Graphic representation of group 1 ≤ 4 mm penetration and group 2 > 4 mm penetrations    

Figure 2. PRISMA flowchart of the screening proces...

  Figure 2. PRISMA flowchart of the screening process

Discussion : Influence of exposing dental implants...

The secondary outcome of this review was the analysis of the clinical and radiological complications related to the penetration of implants in the maxillary sinus. Clinical complication among the different authors ranges from 0 to 14.3%, with a weighted mean complication rate of 3.4%, without finding statistical difference according to the level of implant penetration. The most common clinic...

Figure 1. Graphic representation of implants intru...

  Figure 1. Graphic representation of implants intruding sinus perforating or not the Schneiderian membrane

Results : Influence of exposing dental implants in...

  Analysis of clinical complications Seven studies provide information on clinical complications with a global sample of 232 patients. Clinical complications among the different authors range from 0 to 14.3%, being the weighted mean complication rate 3.4% with an IC 95% [0 7.5] (Fig. 4c) Clinical complications analyzed in the studies were sinusitis, nasal bleeding, nasal obstruction, nasal sec...

Results : Influence of exposing dental implants in...

Results Study screening An initial screening yielded a total of 3551 publications of which 26 potentially relevant articles were selected after an evaluation of their titles and abstracts. Full text of these articles was obtained and evaluated thoroughly. Of these, eight articles (Table 2) fulfilled the inclusion criteria and subsequently were included in the qualitative analysis (Fig. 2). Re...

Materials & methods : Influence of exposing dental...

  Eligibility criteria Articles were included in this systematic review if they met the following inclusion criteria: human prospective or retrospective studies, reporting outcomes of implant placed perforating the sinus floor with implant burs, and without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material. The intrusion into the sinus cavity can occur du...

Materials & methods : Influence of exposing dental...

Materials and methods This systematic review and subsequent meta-analysis follow the guidelines of the PRISMA statement. Focus question The following focus question was developed: Is the intrusion of dental implants into the sinus cavity during implant drilling or implant placement, without regenerative procedure (lateral sinus lift or transalveolar technique) and graft material, has an effec...

Introduction ; Influence of exposing dental implan...

Introduction The edentulous posterior maxillary region often presents with unique challenging conditions in implant dentistry. Limited bone height secondary to pneumatization of the maxillary sinus and the resorption of the alveolar ridge preclude in many instances the installation of dental implants. To compensate for the lack of bone height, several treatment options have been proposed. The ...

Influence of exposing dental implants into the sin...

Influence of exposing dental implants into the sinus cavity on survival and complications rate: a systematic review   Abstract Background After tooth loss, the posterior maxilla is usually characterized by limited bone height secondary to pneumatization of the maxillary sinus and/or collapse of the alveolar ridge that preclude in many instances the installation of dental implants. In order ...

Figure 5 Postoperative orthopantomogram

  Figure 5 a Postoperative orthopantomogram. b Follow-up orthopantomogram. c Follow-up standard periapical radiogram (implants i42 and i44). d Follow-up standard periapical radiogram (implants i32 and i34)

Figure 4 a–h Prosthetic restauration—follow-u...

  Figure 4 a–h Prosthetic restauration—follow-up examination. Intraoral and perioral views of a rehabilitated female patient. (She asked explicitly only for implantological treatment in the mandible.)  

Figure 3. a Primary implant stability

  Figure 3. a Primary implant stability. The histogram visualises the distribution of the implant stability quotients (ISQ) for both jaws measured by resonance frequency analysis (Osstell AB, Göteborg, Sweden). b Secondary implant stability. The histogram shows the distribution of the implant stability quotients (ISQ) of osseointegrated implants. According to the measurement implant stabil...

Figure 2. Cumulative implant survival over the fol...

  Figure 2. Cumulative implant survival over the follow-up period. The Kaplan-Meyer diagram visualises the analysis of implant survival in the maxilla and in the mandible (log rank test, p = 0.173) over the follow-up period up to 37 months (Table 4)  

Figure 1. a Closed short expandable dental implan...

  Figure 1. a Closed short expandable dental implant (4.1 × 7 mm). The implant-abutment connection is characterised by an internal hexagon for rotation stability, combining the advantages of conical and parallel surfaces to reduce microgaps and micromovement. The microthread concept and platform switching concept are implemented in the implant shoulder to reduce periimplant bone strain. b...

Table 4 Clinical characteristics of the study coho...

Patient Sex Age (years) Implant position (FDI) Indication categorya Bone quality Prosthetic treatment Follow-up (months) Implant failure 1. T. I. F 80 Maxilla 15, 13, 11, 21, 25 (Σ = 5) IIa D4 Telescope 37 n = 1c 2. G. S. F 65 Mandible 34, 32, 42, 44 (Σ = 4) IIIb D1 Ball attachment 34 None 3. S. Sa. F 64 Maxilla 14, 12, 22, 24 (Σ = 4) ...

Table 3 Prosthetic treatment protocol

Type of prosthetic treatment Session Procedure Fixed denture (bridge) 1 Open impression 2 Abutment check, set-up • Titanium abutments • Non-precious metal framework, completely lined • Neighbouring crowns interlocked 3 Check and insertion of the suprastructure • Cementation (ImProv™, Dentegris, Duisburg, Germany) Combined fixed-removable dentur...

Table 2 Surgical treatment protocol

Surgical protocol Bone quality   D1 D2 D3 D4 1. Drilling sequence (splint) Last drill Last drill Second to last drill Second to last drill 2. Condensing preparation – – (Analogue to last drill) Analogue to last drill 3. Implant insertion (maximum torque ≤ 40 N cm) 4. Expansion (maximum torque ≤ 40 N cm) 5. Evaluation of primary ...

Table 1 Patient recruitment

Inclusion criteria Exclusion criteria 1. Adult patients, male and female 1. Comorbidity ASA category ≥ III 2. Partially/totally edentulous patients 2. Pregnancy, bruxism 3. Alveolar process atrophy Cawood et Howell category ≥ IV 3. Smoking ≥ 10 cigarettes/day 4. Minimum vertical bone height of 7–9 mm for placement of short implants (5–7-mm length)...

Discussion : Novel expandable short dental implant...

Based on an earlier animal histologic study, as well as a clinical up-to-40-month study, which referred to comparable apically expandable implants, authors did not report any periapical inflammatory complications. To eliminate the potential risk of deep intrabony microleakage, it is questionable whether equal biomechanical stability values can be achieved only by the macroth...

Discussion : Novel expandable short dental implant...

In relation to the results by McCullough and Klokkevold, who found that the macrothread design appears to play a positive role in implant stability in the early healing period, this can also be assumed for the employed implant system. Additionally, with regard to the results by Marković and co-authors, a critical stability drop down due to bone remodeling after bone condensing (impla...

Discussion : Novel expandable short dental implant...

The expansion procedure presents an additional bicortical anchorage in the oro-vestibular direction. In hard bone, this might be a disadvantage and lead to asymmetrical expansion. Manufacturers’ recommendations for hard bone should be strongly considered. Regarding resonance frequency analysis, the values are related to bone quality and quantity as well as the exposed impl...

Discussion : Novel expandable short dental implant...

Several investigators analysed the preferred indications of short dental implants in the posterior mandible or maxilla and outlined the cost efficiency compared to additional vertical augmentations. In the present trial, we used a new short implant in both jaws and nearly all possible indication categories were represented, which proves the broad versatility (Table 4). In our study, two imp...

Discussion : Novel expandable short dental implant...

Discussion Recent literature has shown that short implants have achieved growing acceptance in the field of oral implantology. Since the last years, concern has decreased about the length of endosseous implants; it should be noted that all extraoral screw implants are short implants. Nevertheless, there are local physiological and biomechanical differences regarding long-term stability. Th...

Results : Novel expandable short dental implants (...

Results The first results of this longitudinal study include data from 9 patients with an average age of 57 years (range from 44 to 80) in whom 30 implants were inserted (maxilla n = 15, mandible n = 15). All 30 implants in the 9 patients could be inserted without intraoperative problems. Based on intraoperative and radiological findings, the bone quality was assessed...

Material & methods : Novel expandable short dental...

Surgical and prosthetic protocol Planning of the implantological treatment followed usual clinical and radiological examination and, concerning the position and number of implants, the recommended categories from the German consensus conference. The drilling sequence, condensing preparation (where necessary) and manual implant insertion as well as expansion are described in detail...

Material & methods : Novel expandable short dental...

Material and methods Study population and measures The study was designed as a prospective monocentric longitudinal cohort study according to the STROBE criteria. The participants of this study were recruited at the university hospital of Martin Luther University Halle-Wittenberg, Department of Oral and Plastic Maxillofacial Surgery, implantological consultation from 2014 (June...

Introduction : Novel expandable short dental impla...

... the diameter of an implant has greater influence on primary stability than implant length. Based on in vitro analysis, they concluded additionally that especially in patients with poor bone quality, a variation of implant dimensions is expected to lead to a significant increase of primary stability. Furthermore, stress distribution on short implants is affected by the bone-to-...

Introduction : Novel expandable short dental impla...

Introduction Endosseous implants have been established over several decades. The evaluation of treatment results under biomechanical, physiological, psychological, social and economic aspects has been well documented. Furthermore, patient-based outcomes reveal a predictable gain in oral health-related quality of life. Especially in patients with limited vertical bone height, process of treatme...

Novel expandable short dental implants with reduce...

Novel expandable short dental implants in situations with reduced vertical bone height—technical note and first results   Abstract Purpose Short implants often have the disadvantage of reduced primary stability. The present study was conducted to evaluate the feasibility and safety of a new expandable short dental implant system intended to increase primary stability. Methods As a “pr...

Discussion : Occlusal overload with dental implant...

Discussion Treatment planning implant-prosthetic rehabilitation should be dependent on a biomechanical algorithm customized for each patient. Given the lack of a definitive load-bearing analysis for bone supporting implants, an empirical or intuitive dogma, based on a tooth model, has proliferated in the clinical amphitheater. This has led to a penchant for invasive and costly procedures ra...

Occlusal overload with dental implants: a review (...

With implants, the load is transferred directly from the implant to surrounding bone through the ankylosed root analog and adverse effects have not been found to be as pronounced during non-axial loading. However, there are thresholds of non-axial forces that have been shown to cause crestal bone loss around implants. Duyck et al. have shown that a transverse force of 14.7 N applied on a distan...

Occlusal overload with dental implants: a review (...

This has been explained by Frost. He has identified osteocytes as an important part of the cellular machinery of bone functional adaptation. When the strain stimulus surpasses the homeostatic regulatory mechanism threshold, but is below the bone fatigue failure, tissue level strains lead to fluid flow-mediated osteocyte and dendrite perturbation and release of anabolic factors. In turn, osteoblast...

Occlusal overload with dental implants: a review (...

Another reason is that without a periodontal ligament, implant occlusal loads are directly transferred to the bone leading to higher forces to the supporting structure surrounding implants and risk for bony microfracture (peri-implantitis), compared to natural teeth. In order to measure bite forces, the most widely accepted recording device is the strain gauge bite force transduce...

Occlusal overload with dental implants: a review (...

Another reason is that without a periodontal ligament, implant occlusal loads are directly transferred to the bone leading to higher forces to the supporting structure surrounding implants and risk for bony microfracture (peri-implantitis), compared to natural teeth. In order to measure bite forces, the most widely accepted recording device is the strain gauge bite force transduce...

Occlusal overload with dental implants: a review (...

Another reason is that without a periodontal ligament, implant occlusal loads are directly transferred to the bone leading to higher forces to the supporting structure surrounding implants and risk for bony microfracture (peri-implantitis), compared to natural teeth. In order to measure bite forces, the most widely accepted recording device is the strain gauge bite force transduce...

Occlusal overload with dental implants: a review (...

Of note, statistical mediating factors are implant length, diameter, and surface as well as bone quantity D vs. A (Bone quantity relates to the bone volume present. Division A is the height of the bone more than 10 mm. Division B is more than 10 mm in height, but the width at the crest is 2.5–5 mm. Division C is less than 10 mm in height and width atrophied to less than 2...

Occlusal overload with dental implants: a review (...

Similar findings were reported by Kozlovsky et al., who performed a split-mouth design on Beagle dogs, placing prosthetic abutments on implants, either in supra-occlusion or infraocclusion. They found no loss of osseointegration or marginal bone loss with non-inflamed, occlusally overloaded prostheses on dental implants. In fact, the authors demonstrated, in the absence of in...

Occlusal overload with dental implants: a review (...

On the other hand, fatigue microdamage resulting in resorption of the bone may be the product of mechanical stress above this threshold. If this gradient could be defined for implant restorations, it would clarify a topic in implant dentistry that has been fueled more by dogma, expert opinion, and inferences from concepts used for natural teeth. The purpose of this study is to revi...

Occlusal overload with dental implants: a review (...

Abstract Controversy persists as to the role of occlusal overload in peri-implantitis. Animal studies have not revealed the biological threshold for fatigue failure in the peri-implant bone. On the other hand, clinical studies have demonstrated a link between parafunction and implant failure, although variables such as intensity and frequency of loads, as well as bone density, have led to d...

Table 3 Quantitative analysis of CFU counts

Table 3 Quantitative analysis of CFU counts (× 105) from rough and machined surface implants after cleansing by each method   Rough surface Cont G US Air Rot Las Median 137.5 3.4 46.5 13.0 4.8 16.3 Min 73.0 0.3 6.8 0.5 0.6 3.0 Max 785.0 27.0 240.0 35.5 37.0 34.0 Machine surface Cont G US Air Rot Las Median 84.5 0.9 8.5 3.2 3.3 ...

Table 2 Qualitative evaluation by SEM analysis of ...

Table 2 Qualitative evaluation by SEM analysis of micro- and macrothread areas of machined surface implants   Machined surface (microthread) No effect Fair Good Excellent G       + US     +   Air     +   Rot       + Las   +     Machined surface (macrothread) No effect Fair Good Excellent G       + US...

Table 1 Qualitative evaluation by SEM analysis of ...

Table 1 Qualitative evaluation by SEM analysis of micro- and macrothread areas of rough surface implants   Rough surface (microthread) No effect Fair Good Excellent G     +   US   +     Air   +     Rot     +   Las +       Rough surface (macrothread) No effect Fair Good Excellent G     +   US     ...

Figure 6. Comparison of cleansability of each deco...

  Figure 6. Comparison of cleansability of each decontamination method on the different implant surfaces. Asterisk indicates p < 0.05

Figure 5. Quantitative analysis of CFU counts on i...

  Figure 5. Quantitative analysis of CFU counts on rough and machined surface implants after cleansing by each method. Asterisk represents vs Cont; a, vs G; b, vs US; c, vs Air; d, vs Rot; e, vs Las which indicates p < 0.05

Figure 4. SEM analysis of 4 areas. 1 Rough surface...

Figure 4. SEM analysis of 4 areas. 1 Rough surface—microthread area. 2 Rough surface—macrothread area. 3 Machined surface—microthread area. 4 Machined surface—macrothread area

Figure 3. Decontamination methods

  Figure 3. Decontamination methods. a Gauze soaked in saline applied using a sawing motion. b Ultrasonic scaler (SUPRASSON P-MAX, Satelec-Acteon group, Bordeaux, France, power setting: P5, tip: Implant Protect IP3L/R). c Air abrasives (AIR-FLOW MASTER PIEZON®, EMS, Nyon, Switzerland, power setting: water flow 100%, air pressure 75%, powder: AIR-FLOW® PERIO POWDER, nozzle: PERIO-FLOW®...

Figure 2. GC Aadva® implant; 3.3-mm diameter, 8-m...

Figure 2. GC Aadva® implant; 3.3-mm diameter, 8-mm length

Figure 1. Hard resin splint model carrying 6 impla...


Discussion : Evaluation of decontamination methods...

Surface characteristics Through SEM analysis and CFU counts, it was demonstrated that, except for the Er:YAG laser, decontamination of the machined surface implant was easier than that of the rough surface implant regardless of decontamination method. Gauze soaked in saline and the ultrasonic scaler demonstrated a statistically significant difference in CFU counts between the two surfaces. ...

Discussion : Evaluation of decontamination methods...

Our results are also in accordance with their results in terms of the high cleansability of the rotary metal instrument. In addition, the cotton pellet showed moderate cleansability among the tested methods, but the cleansing time for the cotton pellet (60 s) was shorter than that of the titanium brush with (120 s + 60 s)/without (120 s) photodynamic therapy. If adjusting the d...

Discussion : Evaluation of decontamination methods...

Charalampakis et al. examined the effectiveness of mechanical and chemical decontamination methods using titanium disks contaminated intraorally. They employed four decontamination methods: gauze in saline, chlorhexidine, delmopinol, and an essential oil mixture. The authors discovered there was no significant difference in CFU counts among the four methods. In the present study, our findin...

Discussion : Evaluation of decontamination methods...

However, the rotary stainless steel instrument created numerous shallow scratches, especially on machined surface implants. John et al. compared the supragingival plaque cleansability of a rotary titanium instrument to that of a stainless metal curette on contaminated titanium disks. The residual biofilm area left on implant treated with the rotary titanium instrument was significantl...

Discussion : Evaluation of decontamination methods...

However, the rotary stainless steel instrument created numerous shallow scratches, especially on machined surface implants. John et al. compared the supragingival plaque cleansability of a rotary titanium instrument to that of a stainless metal curette on contaminated titanium disks. The residual biofilm area left on implant treated with the rotary titanium instrument was significantl...

Discussion : Evaluation of decontamination methods...

Regarding the air abrasives, the cleansing effect in the SEM analysis was also as considerable as that achieved by the ultrasonic scaler in the present study, in contrast to the results of the aforementioned study. Louropoulou et al. also stated in their systematic review that an air-powder abrasive system with sodium bicarbonate powder could cleanse contaminated rough/smooth implant surface...

Discussion : Evaluation of decontamination methods...

The SEM analysis demonstrated that three different rough surface disks harbored complex and firmly attached biofilms after gauze scrubbing irrespective of which antiseptic or saline was used. However, the disks with a turned surface hosted fewer biofilm clusters after scrubbing. This finding is in line with our result showing the better cleansability of gauze soaked in saline on the m...

Discussion : Evaluation of decontamination methods...

Augthun et al. examined the cultivability of mouse fibroblasts after cleansing machined or plasma-splayed surface implants carried on acrylic plates that had been contaminated with supragingival plaque from individuals. A plastic hand scaler and an air-abrasive system with sodium bicarbonate powder were employed in their study. A similar number of viable fibroblasts were observed after clean...

Discussion : Evaluation of decontamination methods...

Discussion Study design This study was performed following an ex vivo design to overcome the drawbacks of previous studies. One particular difference in this study was the use of a commercially available screw-shaped implant. As the implant shape and design have rather complicated macro- and microstructures compared with titanium disks or different forms of titanium commonly used in experi...

Results : Evaluation of decontamination methods on...

Results Complications During the experiment, three participants experienced small ulcers caused by the implants carried on the splints; however, it did not affect their daily life. Additionally, there were no signs of gingival inflammation in any participant. SEM analysis (Fig 4, Tables 1 and 2) Rough surface implants G and Rot achieved relatively clean implant surfaces compared with Las in...

Materials & methods : Evaluation of decontaminatio...

This study protocol was approved by the ethical committee of Osaka University (H26.E-36). SEM analysis The SEM analysis was performed as previously described. The decontaminated implant samples were fixed with 2% glutaraldehyde-RPMI 1640 immediately for 1 h at room temperature and washed with distilled water. Then, the samples were dehydrated with 100% t-butyl alcohol and freeze-dried. Finall...

Materials & methods : Evaluation of decontaminatio...

At the end of the 4-day experimental period, the implants were carefully removed from the splints by breaking the resin caps that held them in place. Each implant was randomly assigned to a treatment method (Cont, control (no decontamination); G, gauze soaked in saline; US, ultrasonic scaler (SUPRASSON P-MAX, Satelec-Acteon Group, Bordeaux, France; power setting: P5, tip: Implant Protect IP3L/R); ...

Materials & methods : Evaluation of decontaminatio...

Materials and methods Study subjects Eleven participants, nine men and two women between 28 and 42 years of age (mean age 31.3 ± 4.6), were recruited as the study subjects. All participants provided informed consent verbally. Study information was disseminated to participants both verbally and in written form. The inclusion criteria were as follows: Generally healthy subjects Dent...

Background : Evaluation of decontamination methods...

Background Dental implants are now used broadly for recovering loss of masticatory function and esthetics. Although it has been revealed that dental implants can often survive long term, biological and mechanical complications may arise. Recent cross-sectional and retrospective studies noted a higher prevalence of peri-implantitis at the implant and subject level than previously considered. Add...

Evaluation of decontamination methods of oral biof...

Abstract Background To evaluate the effect of several representative decontamination methods of oral biofilms on different implant surfaces. Material and methods Eleven participants wore a hard resin splint carrying 6 rough (GC Aadva® implant; 3.3-mm diameter, 8-mm length) or machined (not commercially available) surface implants for 4 days to accumulate dental plaque naturally on the ti...

Figure 6. Bone debris at the contact interfaces.

    Figure 6. Bone debris at the contact interfaces. a Numbers of debris particles. b Number and size of debris particles. Each dot indicates a debris particle, and dashes indicate median particle sizes. Particle sizes: small, < 1000 μm2; medium, 1000–10000 μm2, and large, ≥ 10,000 μm2. c Particle size distribution

Figure 5. Microscopic analysis of contact interfac...

  Figure 5. Microscopic analysis of contact interfaces. Microscopic observations of the artificial bone-implant and number of debris particles. The small arrows in the panel indicate voids in the implant-bone interface

Figure 4. Torque kinetics

  Figure 4. Torque kinetics. Immediately after insertion terminated, the implant was removed using the same load and rotation speed. Torque kinetics were measured during implant insertion (top) and removal (bottom)

Figure 2. Insertion torque (IT), removal torque (R...

  Figure 2. Insertion torque (IT), removal torque (RT), and implant stability quotient (ISQ)  

Figure 1. Implant code 12S is similar to a commerc...

  Table 2. Implants. Implant code 12S is similar to a commercially available standard single-threaded implant with equal thread pitch and a 1.2-mm lead. The thread length of implant code 06D is doubled by adding the second thread (light blue). The thread length of implant code 06S is doubled by a 50% reduction in pitch and lead angles. Characteristics of each implant are summarized in Table 1....

Table 2 Insertion torque (IT), removal torque (RT)...

Code IT(N•cm) RT(N•cm) ISQ 12S 13.67 (1.88) 11.68 (1.06) 51.40 (2.95) 06D 20.19 (1.61) 17.45 (1.28) 53.77 (2.73) 06S 22.30 (1.78) 20.25 (2.47) 55.66(1.62)

Table 1 Dimensions of implants

Implant code Thread type Pitch (mm) Lead (mm) Lead angle (degree) Total thread length (mm) 12S Single-threaded 1.2 1.2 8.1 64 06D Double-threaded 0.6 1.2 8.1 129 06S Single-threaded 0.6 0.6 4.65 129

Discussion : Effects of implant thread design on p...

The question of placement speed warrants further consideration. Indeed, another advantage of double-threaded implants is placement speed. The implantation speed of 06D was twice that of 06S, and implantation was completed twice as fast. Nevertheless, while plastic bottles and emergency valves have double-threaded screws for faster opening and closing, the effect...

Discussion : Effects of implant thread design on p...

Here, the RT value of each implant was lower compared with their respective IT values, consistent with other reports. The IT and RT values of 06S were highest, followed by 06D and 12S. In contrast, the differences between RT and IT values were highest for 12S, followed by 06D, and in 06S. We reported that the RT decreased more than IT. Thus, 06S had the lowest rate of decline (IT...

Discussion : Effects of implant thread design on p...

In the artificial bone adjacent to 06D, there were more voids compared with those associated with 06S or 12S, which accounts for the increase in torque. The highest numbers and larger sizes of debris particles were associated with 06D, followed by 0S and 12S, indicating the potential for greater tissue damage. These results likely explain the lower (50%) torque value of 06S compared wi...

Discussion : Effects of implant thread design on p...

In the artificial bone adjacent to 06D, there were more voids compared with those associated with 06S or 12S, which accounts for the increase in torque. The highest numbers and larger sizes of debris particles were associated with 06D, followed by 0S and 12S, indicating the potential for greater tissue damage. These results likely explain the lower (50%) torque value of 06S compared wi...

Discussion : Effects of implant thread design on p...

Discussion We show here that increasing thread length and reducing pitch can increase primary implant stability without changing the size of an implant. Compared with the standard single-threaded implant with a 1.2-mm pitch/lead (12S), torque values and ISQ were significantly increased by doubling the thread length by adding the second thread (06D) or by reducing pitch/lead and lead angle o...

Results : Effects of implant thread design on prim...

Results The IT, RT, and ISQ values revealed significant differences among the implants (Table 2). The IT and RT values of 12S were not significantly different compared with published data (IT, 13.13 ± 1.763 N cm; RT, 12.37 ± 1.746 N cm) (Student t test, df = 9, t = 2.91, p < .017). Compared with 12S, the IT and RT values of 06D and 06S were significantly different (147% and 150%, a...

Methods : Effects of implant thread design on prim...

Implants Three types of grade-4 titanium cylindrical nonself-tapping implants (codes 12S, 06D, and 06S) were specially designed and manufactured (Suwa Co., Ltd., Fujiyoshida, Yamanashi, Japan) (Fig. 1 and Table 1). The code 12S single-threaded implant served as a reference. Codes 06D and 06S were designed to double the thread length compared to 12S. Code 06D was a double-threated implant with t...

Effects of implant thread design on primary stabil...

Unfortunately, the effects of double- or triple-threaded implants on primary stability are known for only a few procedures, such as finite element analysis. An excessive lead angle for these implants may jeopardize their ability to sustain axial load despite faster insertion. Further, when micromotion is compared among implants with different lead angles with the same thread pitch, single-threaded...

Effects of implant thread design on primary stabil...

Introduction Secure primary stability is positively associated with successful long-term implant integration to ensure a successful clinical outcome. Initial implant stability is defined as biomechanical stability upon insertion, which is influenced by factors such as bone quantity and quality, geometry of the implant, surgical technique, and insertion torque (IT). New bone develops around the ...

Effects of implant thread design on primary stabil...

Abstract Background Primary implant stability is essential for osseointegration. To increase stability without changing the implant size, the thread length must be extended by reducing pitch, using a double-threaded implant, or reducing pitch/lead and lead angle to half that of a single-threaded implant. Materials and methods We tested the stabilities of these configurations using artificial...

Figure 3. Comparison of standard and over-dimensio...

  Figure 3. Comparison of standard and over-dimensioned protocol. The figure displayed shows the comparison between standard and over-dimensioned protocol. a Displays the measurements obtained by RFA. The unit is ISQ with a range of 0 to 100 (minimum to maximum stability). b Displays the results obtained by the torque in and c by the torque out test. Although, there was no statistically s...

Figure 2. Over-dimensioned protocol

  Figure 2. Over-dimensioned protocol. The over-dimensioned protocol was conducted by a final drill of 1 mm narrower than the implant diameter. The final drill for implants of 3.3. mm was 3.2 mm and of implants measuring 3.75 mm, it was 3.65 mm. Within this study, an over-dimensioned protocol was defined as a final drill larger than recommended by the company, which is in this case 4 o...

Figure 1. Implant types and drilling protocol

  Figure 1. Standard protocol. This figure shows the implant types and drilling protocol used within this study. Standard protocol was conducted by a final drill of 2.80 mm for 3.3 mm implants, 3.20 mm for 3.75 mm implants, and 3.65 mm for 4.2 mm implants. Permissions for reproducing the figures were received from HI-TEC IMPLANTS LTD. Source: Product Catalogue 12th Edition [40]

Table 3 Comparison of implant diameter

  3.3 mm 3.75 mm 4.2 mm Mean (SD) CI Mean (SD) CI Mean (SD) CI ISQ 66.33 (4.59) 63.79–68.88 69.00 (5.98) 64.72–73.28 69.87 (8.88) 64.94–74.78 IT (Ncm) 102.65 (28.42) 86.91–118.39 90.97 (27.54) 71.27–110.67 78.19 (33.28) 59.76–96.62 TO (Ncm) 94.54 (29.09) 78.43–110.65 81.28 (28.89) 60.67–101.88 100.86 (36....

Table 4 Comparison of implant length

  8.0 mm 10.0 mm 11.5 mm 13.0 mm 16.0 mm Mean (SD) CI Mean (SD) CI Mean (SD) CI Mean (SD) CI Mean (SD) CI ISQ 65.5 (8.40) 58.48–72.52 73.17 (3.60) 69.39–76.95 67.11 (6.09) 62.43–71.79 66.15 (8.15) 59.43–73.07 70.67 (4.97) 66.84–74.49 IT (Ncm) 98.23 (18.56) 82.71–113.74 99.49 (43.73) 53.60–145.48 101.02 (36.80) 72.74–...

Table 2 Comparison of manual and machine-driven in...

  Insertion mode — manual insertion Insertion mode — machine-driven insertion   n Mean (SD) CI n Mean (SD) CI ISQ 45 68.33 (6.83) 66.14–70.51 45 70.25 (5.52) 68.38–72.12 IT (Ncm) 45 90.56 (31.27) 80.56–100.56 45 83.94 (31.81) 73.17–94.7 TO (Ncm) 45 93.59 (32.3) 83.27–103.92 45 89.80 (37.32) 77.18–102.43 ISQ impla...

Table 1 Comparison of standard and over-dimensione...

Drilling sequence — standard protocol Drilling sequence — over-dimensioned protocol   n Mean (SD) CI n Mean (SD) CI ISQ 45 68.33 (6.83) 66.14–70.51 30 68.5 (8.82) 65.08–71.92 IT (Ncm) 45 90.56 (31.27) 80.56–100.56 30 63.74 (48.61) 44.89–82.59 TO (Ncm) 45 93.59 (32.3) 83.27–103.92 30 58.35 (40.43) 42.67–74.02 ISQ im...

Discussion : Implant primary stability depending o...

Contrary to the research hypothesis, there was no difference in primary stability between manually and machine-driven inserted implants. To date, little is known about the influence of the insertion mode on the dental implant primary stability. Novsak et al. assumed a better primary stability in implants inserted manually and suspected that this behavior was related to a higher tac...

Discussion : Implant primary stability depending o...

However, caution is recommended when using under-dimensioned drilling protocols: although high insertion torques ensure a greater initial implant stability and prevent adverse micromotions under loading, the induced over-compression could jeopardize the healing process. In addition, high stress is known to alter angiogenesis and impair new vessel formations, to induce local hypoxia and n...

Discussion : Implant primary stability depending o...

Discussion This study was performed in order to investigate changes in primary stability within an experimental setup of different insertion protocols and insertion modes. In order to obtain a high level of diagnostic certainty, three different methods for measurement of primary stability were recorded. As a secondary outcome parameter, potential differences between implants of different le...

Results : Implant primary stability depending on p...

Results Drilling protocol: standard versus over-dimensioned No statistically significant difference in RFA could be measured (Cohen’s d = − 0.022, effect size r = 0.011, p = 0.260), whereas IT values were significantly higher in implants inserted via SP (90.56 ± 31.27 Ncm) in comparison with the ODP (63.74 ± 48.61 Ncm, p = 0.002; Cohen’s d = 0.656, effect size r = 0.312). T...

Methods : Implant primary stability depending on p...

Preparation protocol for oversized osteotomies (ODP) This protocol repeated the steps of the standard protocol but then added a larger final drill. For the 3.3-mm implants, the final drill size was 3.2 mm; for the 3.75-mm implants, the final drill size was 3.65 mm (Fig. 2). RFA To analyze the data, an Osstell® SmartPeg threaded transducer (implant diameter 3.3 and 3.75 mm: SmartPeg Type ...

Methods : Implant primary stability depending on p...

Methods Bone specimens Twenty mandibles from fresh porcine cadavers were obtained from a local slaughterhouse. The animals did not show any macroscopic signs of any pathologic bone conditions. After removal of the surrounding soft tissue, the surfaces of the bone samples were thoroughly cleaned. Each sample was checked macroscopically for irregularities and a minimum thickness of 20 mm at th...

Background : Implant primary stability depending o...

Analyzing those, a decrease in primary and an increase in secondary stability with a shorter healing period for implants became apparent. Kim et al. compared the effect of oversized drilling sockets regarding bone-to-implant contact and bone density after 4 and 8 weeks in an in vivo dog model. They used a final drill of 4.00 mm for implants with a diameter of 4 mm in the oversized group and a ...

Background : Implant primary stability depending o...

With increasing stiffness of the bone-implant interface, the vibration frequency of the sensor increases. While RFA is expressed in hertz, implant stability quotient (ISQ) is the scale used to quantify RFA values (range 1–100). Even though RFA has been reported to be a reliable, reproducible, and objective method to measure the stiffness of bone-implant-complex, it has also been reported that R...

Background : Implant primary stability depending o...

Background A reliable option for replacing teeth is the insertion of osseointegrated implants. Dental implant primary stability (DIS) has also been reported to be a fundamental prerequisite for long-term success of dental implants, even though osseointegration has also been achieved without a certain amount of primary stability. Primary stability has been defined as the ability to withstand axi...

Implant primary stability depending on protocol an...

Abstract Background Dental implant primary stability is thought to be a fundamental prerequisite for the long-term survival and success. The aim of this study was to analyze the influence of protocol and insertion mode on dental implant stability ex vivo. One hundred and twenty implants were inserted either manually or machine-driven into porcine mandibles by a standard or over-dimensioned pro...

Figure 5. The effect of grade 4 and grade 5 implan...

  Figure 5. The effect of grade 4 and grade 5 implant particles on human gingival fibroblast viability in vitro. Viability was determined using an MTT metabolic activity assay. Cells were exposed to either a dissolution products (ions and nanoparticles) or b culture medium containing suspended implant particles throughout the duration of the culture period. Cells were exposed to various con...

Figure 4. Titanium (Ti) and vanadium (V) content i...

  Figure 4. Titanium (Ti) and vanadium (V) content in Dulbecco’s Modified Eagle Medium (DMEM). a, b Dissolution products (media filtered through 0.2 μm PTFE membrane following initial soaking of the particles for 3 days) and c, d DMEM sampled during cell culture studies where cells were cultured with the particles over a period of 10 days (particles removed prior to ICP measurem...

Figure 3. Titanium (Ti) and vanadium (V) release f...

  Figure 3. Titanium (Ti) and vanadium (V) release from the particles in simulated body fluid (SBF). Experimental duration was 10 days. Results presented as mean ± standard deviation, n = 3

Figure 2. EDX spectra of particles produced by the...

  Figure 2. EDX spectra of particles produced by the mock implantoplasty procedure (SEM images in Fig. 1). a, b Particles from grade 4 commercially pure titanium implant, a angular microparticles and b small spheres. c, d particles from grade 5 titanium alloy, c angular microparticles and d small spheres (grade 5)    

Figure 1. Representative photo of implants and SEM...

  Figure 1. Representative photo of implants and SEM images of particles produced by mock implantoplasty procedure. a–c Straumann 021.4512, bone level, diameter 4.1 mm, regular CrossFit®, SLA® 12 mm Roxolid® (commercially pure grade 4 titanium). d–f Biohorizons PBR 50105, RBT 5.0 × 10.5 mm, 5.7 Platform (grade 5 titanium alloy). Arrows indicate titanium oxide spheres. Scale ba...

Discussion : Particle release from implantoplasty ...

Further, the effect of implant particles on other cell types within the oral and systemic environments should not be overlooked. Although the health hazards of FPs and NPs are relatively less well established, literature in the fields of toxicology does indicate a glimpse of possible toxicity that should compel clinicians to carefully weigh the possible adverse human health effec...

Discussion : Particle release from implantoplasty ...

This is due to the lack of vanadium and possibly larger particle size. Here, G5 particles are. Although a range of particle size of G5 was measured in this study, a portion of the particles generated from the mock implatoplasty process in the current study is comparable to that reported by Pioletti et al.. The internalisation of G5 particles, especially sub-micron particles, and the su...

Discussion : Particle release from implantoplasty ...

There was no distinct difference in the amount of titanium ions released from G4 and G5 particles. Direct exposure to G5 implant particles in culture did result in significantly reduced cell viability at all-time points, from 3 to 10 days of culture, while G4 implant particles demonstrated no adverse effect on cell viability (Fig. 5b). The cytotoxic effects of vanadium are well docum...

Discussion : Particle release from implantoplasty ...

Discussion Unalloyed titanium, often referred to as commercially pure grade 4 titanium (CpTi), usually contains some trace elements of carbon, oxygen, nitrogen and iron (American Society for Testing and Materials international standards). These trace elements improve the mechanical properties of CpTi and are found in higher amounts from grade 1 to 4 CpTi. Many dental implants are made from ...

Results : Particle release from implantoplasty of ...

Results Particles released from implants following the mock implantoplasty procedure were collected, and microparticle size of particles produced from the grade 4 (G4) and grade 5 (G5) implants was 77.4 ± 9.1 μm (modal number 66.3 μm) and 48.4 ± 6.4 μm respectively (modal number 43.1 μm). DLS analysis showed nano-sized particles were also present: hydrodynamic diameters were 125.4...

Materials & methods : Particle release from implan...

The media were filtered through 0.2 μm PTFE membrane syringe filters following incubation to remove the particles before use in cell culture. Group 2 (particle): Sterilised grade 4 and 5 Ti particles were suspended in DMEM at concentrations of 0.75, 1.5 and 3 mg ml−1 and used for cell culture without filtering. Basal DMEM and DMEM containing unprocessed grade 4 and 5 implants were used a...

Materials & methods : Particle release from implan...

Ion release from titanium particles Simulated body fluid (SBF) was chosen as the dissolution test solution as we were interested in what happens when the particles become embedded in the soft/hard tissue rather than their interaction with saliva. SBF was prepared using the Kokubo method. Seven hundred millilitres of deionised (DI) water in a 1-L polypropylene beaker was warmed to 37 °C in a wa...

Materials & methods : Particle release from implan...

Materials and methods Materials Reagents and solvents were purchased from Sigma-Aldrich (Dorset UK). Commercially pure grade 4 titanium implants (n = 3) were purchased from Straumann (Sussex UK, Model number 021.4512, bone-level implant diameter 4.1 mm, Regular CrossFit®, SLA® 12 mm Roxolid®) (Fig. 1a). Grade 5 Ti-6Al-4 V titanium alloy implants were purchased from Biohorizons (Berk...

Background : Particle release from implantoplasty ...

However, if previous records are available, then the diagnosis can be made with any increase in pocket depth with post remodelling bone loss of greater than 0.5 mm in the presence of bleeding and/or suppuration on gentle probing, A number of studies suggested this inflammatory disease is associated with anaerobic plaque bacteria. It has also been suggested peri-implantitis can also be related to...

Background : Particle release from implantoplasty ...

Background Dental implants offer a viable long-term treatment option for patients with missing teeth. The use of metallic dental implants has relatively high reliability and long-term success rates; however, it is not without complications and the need for ongoing maintenance persists. Particles are generated during the life span of an implant, and this can have significant physiological implic...

Particle release from implantoplasty of dental imp...

Abstract Background With increasing numbers of dental implants placed annually, complications such as peri-implantitis and the subsequent periprosthetic osteolysis are becoming a major concern. Implantoplasty, a commonly used treatment of peri-implantitis, aims to remove plaque from exposed implants and reduce future microbial adhesion and colonisation by mechanically modifying the implant sur...

Figure 6. Marginal bone loss (MBL) in SLA and MK-I...

  Figure 6. Marginal bone loss (MBL) in SLA and MK-III implants within the abnormal group. MBL is significantly larger in MK-III implants than SLA implants during the follow-up period.

Figure 5. Cancellous bone densities in SLA and MK-...

Figure 5. Cancellous bone densities in SLA and MK-III implants within the abnormal group. The cancellous bone density shows no significant difference between SLA and MK-III implants at baseline

Figure 4. Cancellous bone densities in the normal ...

Figure 4. Cancellous bone densities in the normal and abnormal groups of women are shown. Cancellous bone density is significantly higher in the normal group than in the abnormal group

Figure 3. The overview on BTM values are shown

Figure 3. The overview on BTM values are shown. The bone turnover markers measured are osteocalcin (OC), bone-specific alkaline phosphatase (BAP), pyridinoline cross-linked carboxyterminal telopeptide of type I collagen (ICTP), and crosslinked N-telopeptide of type I collagen (NTX)

Table 2 Age, sex, and follow-up period between the...

  Normal group Abnormal group P value r Age [years] 57.3 63.1 0.038* 0.49 Male (%) 7 (100) 0 (0) 0.0043* 0.66 Female (%) 2 (18) 9 (82) Follow-up period [months] 21.3 21.4 0.85    

Table 1 Each parameter of the 18 patients who fulf...

Case no. Gender Age [years] Bone turnover marker Position Implant Bone Density [HU] Follow-up period [m] Marginal bone loss [mm] OC BAP ICTP NTX 1 M 60.2 5.8 8.1 2.7 11.4 7┐ SLA 1112.63 10 -               6┐ SLA 815.75 10 - 2 M 51.3 4.9 9.9 3.0 12.0 6┐ SLA 746.00 6 0.32               5┐ SLA...

Figure 2. Measurement of marginal bone loss (MBL) ...

Figure 2. Measurement of marginal bone loss (MBL) on dental radiography. MBL is measured using Image J software (National Institutes of Health, Bethesda, MD, USA). The reference points for the measurements are the implant platform (the horizontal interface between the implant and the abutment), the implant tip, and the first bone-implant contact (FBIC). The length from the implant platform to th...

Figure 1. Measure the bone density at the implant ...

Figure 1. Measurements on computed tomography (CT) images. The imaging data are stored in Digital Imaging and Communications in Medicine format and loaded into an implant planning software program (Simplant®, Dentsply Implants, Leuven, Belgium). Buccopalatal or buccolingual cross-sectional CT slices are used to measure the bone density at the implant placement sites in Hounsfield units. The mea...

Discussion : Bone turnover markers to assess jawbo...

Many reports of the relationship between dental implants and osteoporosis have been published, but few have focused on bone quality. Bone quality is multifactorial and difficult to classify because it varies from patient to patient. The present study focused on BTM, which is one of the clinical indicators of bone quality. A prospective study confirmed that elevation of a BTM can predict frac...

Discussion : Bone turnover markers to assess jawbo...

The cancellous bone density in the abnormal BTM group was significantly lower than that in the normal BTM group. This suggests that cancellous bone with a high BTM was likely to actually be poor medullary bone. There were three patterns of low BMD: high values of bone formation markers only, high values of both bone formation and bone resorption markers, and high values of bone resorption ma...

Discussion : Bone turnover markers to assess jawbo...

Discussion Nine (82%) of the11 female patients in this study had at least one BTM measurement outside the normal range. The abnormal BTM values in these women were pronounced. No abnormal BTM valued were observed among the men. According to the Japanese Guidelines for the Prevention and Treatment of Osteoporosis, the diagnostic criteria for osteoporosis include the following: (1) fragility ...

Results : Bone turnover markers to assess jawbone ...

Results Eighteen patients (11 women, 7 men; mean age 60.2 years) fulfilled the inclusion criteria. There was no significant difference between men (57.3 ± 5.0 years) and women (63.1 ± 6.0 years). After measuring the BTMs and assessing bone density, 35 implants were placed (18 MK-III, 17 SLA). The mean follow-up duration was 21.4 months (Table 1), during which time follow-up observatio...

Materials and methods : Bone turnover markers to a...

Patient selection Patients treated at Hiroshima University Hospital were included in the study if they remained partially edentulous in the planning area for at least 3 months, if one or two splinting fixed prostheses in the mandible posterior area were planned, if they had never been treated for osteoporosis, and if they had no subjective or objective symptoms of osteoporosis, such as back pai...

Background : Bone turnover markers to assess jawbo...

Surgery Implants (SLA® (sandblasted and acid-etched, internal connection system), Straumann AG, Basel, Switzerland, or Branemark® System Mk-III (TiUnite, external connection system), Nobel Biocare, Gothenburg, Sweden) were used depending on the patient’s clinical characteristics. The operating surgeon was blinded to the bone analysis results and was unaware of the bone density...

Background : Bone turnover markers to assess jawbo...

Materials and methods Patient selection Patients treated at Hiroshima University Hospital were included in the study if they remained partially edentulous in the planning area for at least 3 months, if one or two splinting fixed prostheses in the mandible posterior area were planned, if they had never been treated for osteoporosis, and if they had no subjective or objective symptoms of osteo...

Background : Bone turnover markers to assess jawbo...

Background Dental implants have become an established prosthodontic treatment for missing teeth, with survival rates now exceeding 97%. The most popular current method of bone quality assessment is that developed by Lekholm and Zarb, who introduced a scale that ranges from 1–4 and is based on a radiographic assessment and the sensation of resistance experienced by the surgeon when preparing t...

Bone turnover markers to assess jawbone quality pr...

Abstract Background Bone quality is as important as bone mineral density in terms of bone strength. Bone turnover markers (BTMs) are clinical indicators of bone quality. In implant dentistry, bone quality is considered equivalent to bone density on radiographic assessments. The purpose of this study was to determine whether the BTM values are reflected in jawbone condition by evaluating the re...

Figure 6. Sample images of misdetected implants

  Figure 6. Sample images of misdetected implants. a Both implants could not be detected because of the shadow of the spina. b Left implant was detected correctly as MK III/IIIG, but the right implant was not detected because of an unclear image  

Figure 5. Average precision (AP) of each implant s...

  Figure 5. Average precision (AP) of each implant system in all images. MK III/MK III Groovy: MK III/IIIG, MK IV/Speedy Groovy: MK IV/SG, bone level: BL and Genesio Plus ST: Genesio

Figure 4. Ratio of implant systems detected correc...

  Figure 4. Ratio of implant systems detected correctly to all detected systems (True Positive ratio). MK III/MK III Groovy: MK III/IIIG, MK IV/Speedy Groovy: MK IV/SG, bone level: BL and Genesio Plus ST: Genesio

Figure 3. The total number of implant systems dete...

Figure 3. The total number of implant systems detected correctly (TPs) and those detected as other prostheses (FPs). MK III/MK III Groovy: MK III/IIIG, MK IV/Speedy Groovy: MK IV/SG, bone level: BL and Genesio Plus ST: Genesio

Figure 2. Total number of objects of each implant ...

    Figure 2. Total number of objects of each implant systemin all images. MK III/MK III Groovy: MK III/IIIG, MK IV/Speedy Groovy: MK IV/SG, bone level: BL and Genesio Plus ST: Genesio  

Figure 1: Sample image for calculating IoU (MK III...

  Figure 1. Sample image for calculating IoU (MK III implant). The light gray square indicates the ground-truth bounding box, and the dark gray square indicates the predicted bounding box. IoU value was calculated that the overlapped area of light gray and dark gray squares was divided by the united area of light gray and dark gray squares.

Conclusion : Identification of dental implants usi...

Conclusion Though there are several issues that still need to be addressed, implant systems can be identified from panoramic radiographic images using deep learning-based object detection. To increase the learning performance and apply this system in clinical practice, a higher quality and larger number of implant images and images of other implants will be needed in subsequent studies. ...

Results & Discussion : Identification of dental im...

To identify implant systems from radiographic images, dental radiography, panoramic radiography, and computed tomography were considered. In this system, it is thought that implant systems are identified by the shape of the collar, groove, and apex of the implant images, which are unique characteristics of each implant. Consequently, the quality of the training images is important so that these ...

Results & Discussion : Identification of dental im...

The second system employs nine questions about implant characteristics. The database returns candidate matching implants based on the answers to these questions, and dentists must match them with those of the patient. Both of these systems require dentists to check whether two images of an implant are the same to identify the implant system. In contrast, the system in this study is based on de...

Results & Discussion : Identification of dental im...

Results At least 240 instances of each implant system were detected in the panoramic radiographic images: the most common type was MK III/IIIG (1919 instances) and the least common was Genesio (240 instances; Fig. 2). The number of implants detected correctly (True Positive: TP), and those detected as other systems (false positive: FP) are shown in Fig. 3. The number of both TP and FP were the ...

Method : Identification of dental implants using d...

Methods Data collection Panoramic radiographs were obtained from patients who received implant treatment in the Department of Prosthodontics, Gerodontology and Oral Rehabilitation at Osaka University Dental Hospital after January 2000. Panoramic radiographs with unknown implants were excluded and totally 1282 images were used to annotate implants. All images were JPEG files that were resized t...

Background : Identification of dental implants usi...

Background Dental implants were developed in the 1980s, and they are now used for patients with missing teeth globally. Their effect on dental treatment is great, and various improvements in patients’ quality of life have been reported. Implant treatment is no longer unusual for either patients or dentists. However, because more than 30 years have passed since implants were introduced into cl...

Identification of dental implants using deep learn...

Abstract Background In some cases, a dentist cannot solve the difficulties a patient has with an implant because the implant system is unknown. Therefore, there is a need for a system for identifying the implant system of a patient from limited data that does not depend on the dentist’s knowledge and experience. The purpose of this study was to identify dental implant systems using a deep le...

Figure 6. Von Mises stress distribution on bone

  Figure 6. Figure 6. a–d Von Mises stress distribution on bone. From a to d: L-M, ZL-M, L-V, and ZL-V respectively. The stress concentration occurred in the cortical bone around the neck of the implant. Groups L-M and ZL-M were quite similar and reduced stress

Figure 5. a–d Von Mises stress distribution on a...

Figure 5. a–d Von Mises stress distribution on abutment. From a to d: L-M, ZL-M, L-V, and ZL-V respectively. Von Mises stresses were relatively similar and concentrated at the coronal part of the abutment in all groups Figure 5. a–d Von Mises stress distribution on abutment. From a to d: L-M, ZL-M, L-V, and ZL-V respectively. Von Mises stresses were relatively similar and concentrated ...

Figure 4. a–d Von Mises stress distribution on i...

Figure 4. a–d Von Mises stress distribution on implant. From a to d: L-M, ZL-M, L-V, and ZL-V respectively Figure 4. a–d Von Mises stress distribution on implant. From a to d: L-M, ZL-M, L-V, and ZL-V respectively

Figure 3. a–d Maximum principal stress distribut...

Figure 3. a–d Maximum principal stress distribution on crown restoration. From a to d: L-M, ZL-M, L-V, and ZL-V respectively Figure 3. a–d Maximum principal stress distribution on crown restoration. From a to d: L-M, ZL-M, L-V, and ZL-V respectively

Figure 2. The graph of the interaction of the mate...

Figure 2. The graph of the interaction of the materials and restoration design

Table 4 Descriptive statistical analysis of the gr...

Group N Mean (N) Standard deviation Minimum Maximum L-M 12 2891.88a 410.12 2079.74 3486.96 L-V 12 2077.37bc 356.59 1220.96 2493.39 ZL-M 12 1750.28c 314.96 1084.36 2163.95 ZL-V 12 2202.55b 503.14 1292.20 2912.81

Table 3 The properties of the materials used in FE...

Material Young’s modulus (GPa) Poisson ratio Reference E.max CAD 95 0.20 [1] Vita Suprinity 65 0.23 [2] Vita VM 11 65 0.23 * E.max Ceram 64 0.23 [4] Implant and abutment 114 0.34 [5] Cortical bone 13.7 0.3 [5] Spongious bone 1 0.3 [5]

Figure 1. Crown restoration design

Figure 1. Crown restoration design

Table 2 The materials in the groups

Groups N Materials L-M 12 IPS e-max CADIPS e.max CAD glaze L-V 12 IPS e-max CADe.max Ceram DentinIPS e.max Ceram Glaze ZL-M 12 Vita SuprinityVita Akzent Plus ZL-V 12 Vita SuprinityVM-11Vita Akzent Plus

Table 1 The materials used in the study

Material Chemical composition (%) Coefficient of thermal expansion (10−6 K−1) Flexural strength (MPa) Manufacturer IPS e.max CAD; lithium disilicate glass ceramic (LDS) SiO2 (57–80), Li2O (11–19), K2O (0–13), P2O5 (0–11), ZrO2 (0–8), ZnO (0–8), Al2O3 (0–5), MgO (0–5), coloring oxides (0–8) 10.2 360 Ivoclar Vivadent IPS e.max Ceram; low-fusing nan...

Conclusion : Comparison of CAD/CAM manufactured im...

Conclusions Within the limitation of the present study, it can be concluded that the restoration design affected the failure load of ceramics. Monolithic design had a statistically significant effect on the failure load of two different ceramics (LDS > ZLS). Veneer application had opposite effects on two different ceramics which increased the failure load of ZLS and reduced it for LDS witho...

Discussion : Comparison of CAD/CAM manufactured im...

Zheng et al. compared the stress distribution of the same veneering ceramic on different cores and concluded that the zirconia core was clearly different from other materials with higher tensile stresses at the veneer core interface because the increasing differences between the elasticity modulus of the core and the veneer transmitted higher stress concentrations to the cores. Con...

Discussion : Comparison of CAD/CAM manufactured im...

Veneer application provided additional strength to the ZLS crowns in contrast to the LDS crowns. The higher failure load of the veneered ZLS crowns (2202.55 N; group L-V 2077.37 N) may be associated with the higher flexural strength of the veneering porcelain VM-11 (100 MPa; emax Ceram 90 MPa). These veneered groups had a statistically significant difference from the monoli...

Discussion : Comparison of CAD/CAM manufactured im...

Similar results were presented in a study of Traini et al. as it was concluded that ZLS was comparable to that of existing zirconia-based ceramics and was suitable for oral function even in the posterior regions. In the literature, there have been few studies on this ceramic and a limited number of them include the failure load of the material. In one of these studi...

Discussion : Comparison of CAD/CAM manufactured im...

In literature, it has been stated that the failure load of LDS crowns was higher than veneered zirconia and could be comparable with metal ceramic systems. Doğan et al. evaluated the fracture strength of different CAD/CAM-manufactured crowns and concluded that the monolithic LDS crowns had the highest fracture resistance. Present study confirmed as monolithic LDS crowns demonstrated so satisfying...

Discussion : Comparison of CAD/CAM manufactured im...

Discussion Implant-supported restorations have been accepted as an alternative treatment for the rehabilitation of edentulous spaces. Despite the high success rates, implant failures are inevitable and classified as early or late implant failures. Late implant failures are observed after prosthetic restoration which is primarily related to biomechanical complications. Since occlusal loads are t...

Results : Comparison of CAD/CAM manufactured impla...

Results Descriptive analysis (mean, standard deviation (SD), minimum, maximum) of the groups is presented in Table 4. Group L-M exhibited the highest failure load values (2891.88 N ± 410.12 N), and the lowest values were observed in group ZL-M (1750.28 N ± 314.96 N). Two-way ANOVA indicated a statistically significant difference between materials and veneering technique (p = 0.00 < ...

Method : Comparison of CAD/CAM manufactured implan...

  Statistical analysis The statistical analysis was performed with SPSS 24.0 (SPSS Inc, Chicago, USA). The Kolmogorov–Smirnov normality test was used to evaluate whether the data distribution of the groups was normal. The homogeneity of the variances was analyzed by Levene’s test. Since test results indicated that data distribution of the groups was normal and the variances were homogenous,...

Method : Comparison of CAD/CAM manufactured implan...

All crowns were subjected to a combination firing that included crystallization and glaze firing according to each manufacturer’s guidelines in the ceramic furnace (Vita Vacumat 6000 M, Vita Zahnfabrik, Bad Sackingen, Germany). For veneered restorations, the design mode was changed to “split,” and the core was constructed in 0.6-mm thickness. In group L-V (n = 12), e.max ...

Method : Comparison of CAD/CAM manufactured implan...

Methods Preparation of test groups This study tested the current glass ceramic ZLS by comparing LDS with monolithic and conventional veneering techniques in implant-supported crowns: group L-M: lithium disilicate ceramic (monolithic), group L-V: lithium disilicate ceramic (conventional veneering), group ZL-M: zirconia-reinforced lithium silicate ceramic (monolithic), group ZL-V: zirconia-reinf...

Background : Comparison of CAD/CAM manufactured im...

Background Implants have been successfully used to replace missing teeth for many years. Notwithstanding the high success rates, complications such as screw loosening and/or fracture, prosthesis fracture, and even implant fracture are inevitable. The reasons of the complication may be related to decreased proprioception and low tactile sensitivity which makes implant-supported crowns more susc...

Comparison of CAD/CAM manufactured implant-support...

Abstract Background Present study compared the failure load of CAD/CAM-manufactured implant-supported crowns and the stress distribution on the prosthesis-implant-bone complex with different restoration techniques. Methods The materials were divided into four groups: group L-M: lithium disilicate ceramic (LDS, monolithic), group L-V: LDS ceramic (veneering), group ZL-M: zirconia-reinforced l...

Conclusion : Study of implants (6)

5 CONCLUSION This open cohort, retrospective study evaluated risk indicators associated with marginal bone loss (MBL) through the analysis of 4,591 dental implants, of various designs, placed in private practice and followed‐up for 5 to 10 years. Significant risk indicators for bone loss were found to include autoimmune disease, heavy smoking, bisphosphonate therapy, implant location, diamete...

Discussion : Study of implants (6)

In this study, prevalence of mucositis varied from nearly 50% of patients using a “strict” BOP threshold (IMI ≥1) (49.5%) compared with 18.2% if using the “relaxed” IMI threshold (IMI ≥2) (see supplementary Tables 3 and 4 in online Journal of Periodontology). As the implants used in the current study were either platform shift or 1‐stage design 3 mm and BOP+ but no co...

Discussion : Study of implants (5)

This is in support of systematic reviews of ridge augmentation that often show some loss of grafted bone volume and furthermore, it has been speculated that although the bone graft at time of placement may provide stable hard tissue, the basal bone may be the actual bone that is integrated to the implant. 4.1 Effect of threshold selection on reported prevalence of peri‐implantitis The choi...

Discussion : Study of implants (4)

However, the one‐stage tapered effect (TE) design was found to have increased initial MBL at base line (stage 2) (Figure 2C). For the TE design, the increased early MBL may be related to bone compression and a learning curve associated with placement of tapered implants. Two stage platform switch implants typically have bone loss of about 0.5 mm. For the bone level platform shift design, the...

Discussion : Study of implants (3)

The posterior mandible and posterior maxilla had equivalent crestal bone levels at the start but then the rate of MBL in the posterior maxilla was found to increase at a faster rate when compared with other locations (Figure 2A). This may be a result of crestal compression in lower density bone leading to MBL as described in finite element analysis. Indeed it was noted that about 6% of sites h...

Discussion : Study of implants (2)

This is a unique finding in the literature and may reflect altered remodeling potential of bone, or it may also be the effect of a few outlier cases where sudden MBL was noted in some but not all bisphosphonate cases. Conclusions drawn are limited however as the duration or dose of bisphosphonate therapy was not recorded in this study. Interestingly, diabetes (pooled type 1 and type 2) was not ...

Discussion : Study of implants (1)

DISCUSSION An analysis of risk indicators for changes in crestal bone level, as a measure of bone loss (MBL), surrounding dental implants has been reported in this study. Furthermore, the impact of the choice of thresholds in determining prevalence of mucositis and peri‐implantitis has been considered. Importantly, this private practice report includes conventional patients and sites as well ...

Result : Study of implants (3)

3.3.3 Implant design Pairwise comparisons for CBL at the start between the four implant design groups revealed a similarity between standard and standard plus implants as well as between bone level and tapered effect implants (Figure 2C). However, a significant difference (P value 

Result : Study of implants (2)

3.1 Risk indicators for bone loss (MBL) All potential factors and related correlations were evaluated. Table 1 shows only variables that related significantly to changes in CBL over time in a multivariate model. Figures 1 through 3 illustrate the results of Table 1. The “start” refers to baseline at 3 months). 3.2 Patient‐related risk indicators No significant effect on CBL was observ...

Result : Study of implants (1)

RESULTS The study cohort of 2,060 patients and 4,591 implants was followed for up to 133 months, with a mean of 32.2 ± 26.8 months. The number of implants for each time period was; n = 2,372 at 2 to 3 years, n = 1,178 at 4 to 5 years, and n = 560 at 6 to 10 years. There were 32 implant failures resulting in cumulative survival rates of 99.3%, 99.0%, and 98.4% at 3, 5, and 7 years, respectively, ...

Materials & methods : Study of implants (3)

Mucositis was determined using either the “strict” criteria, IMI ≥1, as an indication for mucositis or the “relaxed” criteria, IMI ≥2, as an indication of mucositis. We defined peri‐implantitis as the combination of mucositis and MBL ≥1.0 mm, at least 1 year after installation. 2.1 Statistical analysis CBL and MBL are scale variables and have been summarized by calculating the m...

Materials & methods : Study of implants (2)

Radiographs were taken and evaluated by the same examiner that placed the implants (DF). For each case the real implant length served as the calibration value to derive the Distance from Implant shoulder to the first Bone to implant contact (DIB). CBL was defined as DIB minus the neck length (NL) of an implant with the following standardization values to account for different implant neck designs...

Materials & methods : Study of implants (1)

MATERIALS AND METHODS A description of the study cohort presenting explanatory variables and univariate and multivariate implant survival analysis has been previously published. Details on recall and follow up are further described in a companion paper. In brief, this was a retrospective study consisting of 2,060 patients with an initial total of 4,591 implants. All implants were placed between...

Introduction : Study of implants: Analysis of risk...

INTRODUCTION Although dental implants have been reported to have fairly high survival rates of 95.7% at 5 years and 92.8% at 10‐years, it is also known that progressive marginal bone loss and peri‐implantitis remain a significant potential complication. The 2012 European academy of osseointegration (EAO) consensus report estimated the prevalence of peri‐implantitis to be at 10% of implants ...

Study of implants: Analysis of risk indicators for...

Retrospective cohort study of 4,591 dental implants: Analysis of risk indicators for bone loss and prevalence of peri‐implant mucositis and peri‐implantitis   Abstract Background Due to the risk of peri‐implantitis, following dental implant placement, this study aimed to evaluate risk indicators associated with marginal bone loss from a retrospective open cohort study of 4,591 denta...

Table 5. Differences between 5 years and 10 years ...

  At 5 years of function At 10 years of function   Patient level Implant level Patient level Implant level   n % n % n % n % Failure 15 3.16% 31 1.56% 24 5.05% 47 2.36%   Δ 5‐ to 10‐year failure       1.89%   0.80%   Peri‐implantitis 40 8.42% 61 3.19% 76 16% 186 9.72%   Δ 5‐ to 10‐year peri‐impla...

Figure 1. Peri‐implantitis over the study period...

Figure 1. Peri‐implantitis over the study period of 10 years at patient and implant level

Table 4. Survival and success rate at implant and ...

  Rehab. solution Patient level Implant level Survival rate Total 91.8% 96.1%   Fixed full‐arch bridge   90.5%   Implant‐supported overdenture   82.9%   Fixed partial denture   99.2%   Single‐tooth replacement   99.6% Peri‐implantitis rate Total 24.4% 12.9%   Fixed full‐arch bridge   14.3%   Implant‐...

Table 3. Life table analysis and cumulative surviv...

  Cumulative survival rate Cumulative success rate Time of functional loading (Years) Patient level Implant level Patient level Implant level 1 to 2 100% 100% 98.7% 99.5% 2 to 3 99.2% 99.7% 97.2% 98.8% 3 to 4 98.5% 99.4% 95.5% 97.9% 4 to 5 97.7% 98.9% 93.5% 96.7% 5 to 6 96.6% 98.4% 91.3% 95.3% 6 to 7 95.5% 97.9% 88.5% 93.6...

Table 2. Baseline information (1,991 implants)

Demographic variables Implants (%) Age ≥61 years 315 (15.8) ≤60 years 1,676 (84.2) Sex Male 904 (45.4) Female 1087 (54.6) Systemic disorders11 under medical supervision. With 173 (8.7) Without 1,818 (91.3) Smoking habits22 ≤20 cigarettes. With 146 (7.3) Without 1,845 (92.7)   Anatomic variables ...

Table 1. Patient and implant distribution among gr...

      Total   Patients Implants Clinical condition Men Women n % Rehab. solution n % n % Totally edentulous 40 50 90 19 Fixed full‐arch bridge 32 6.74 348 17.48           Implant‐supported overdenture 58 12.21 211 10.60 Partially edentulous 73 82 155 33 Fixed partial denture 155 32.63 732 36.77 Mono‐edentul...

Conclusion : A study on peri‐implant complicatio...

CONCLUSIONS Peri‐implantitis began to appear more frequently after the fifth year of functional loading, with a peak of incidence observed after the seventh year, especially between the seventh and eighth years. The incidence of peri‐implantitis increased when the data were analyzed from the fifth year to 10 years of function. Consequently, studies that consider a follow‐up period

Discussion : A study on peri‐implant complicatio...

The rate of peri‐implantitis observed in this study at 10 years, agreed with that described by Bragger et al. and Karoussis et al. in which peri‐implantitis occurred in 15.4% of the implants after a mean observation period of 10 years. Simonis et al. (2010) reported a prevalence of 16.9% of peri‐implantitis after an observation period of 10 to 16 years. The study of de Waal et al. desc...

Discussion : A study on peri‐implant complicatio...

During the interval between the sixth and seventh year of functional loading, a slightly higher rate of failures than that in the previous years was observed. The ratio between the rate of peri‐implant complications and the time of function was even more evident for peri‐implantitis, which showed a significant increase after the seventh year of functional loading, with a more evident increase...

Discussion : A study on peri‐implant complicatio...

The aim of this retrospective study was to assess the survival and success rates as well as the incidence of peri‐implantitis in patients with a history of periodontitis who followed an individual maintenance program and supportive periodontal and peri‐implant treatment (SPT), and with 1 to 10 years of implant functional loading. The results obtained in the present study show that peri‐impl...

Results : A study on peri‐implant complications ...

A total of 1,991 implants (475 patients) with 10 years of functional loading met the inclusion criteria and were included in this study: 90 patients were totally edentulous (559 implants), 155 patients were partially edentulous (732 implants), and 230 patients were mono‐edentulous (700 implants) (Tables 1 and 2). Table 3 shows the life table analysis and cumulative survival and success rate and...

Materials & methods : A study on peri‐implant co...

When a two‐stage technique was performed (i.e., sinus floor augmentation without implant insertion or staged‐approach GBR), a healing period of at least 6 months was observed before implant insertion. The implants were functionally loaded after 3 to 6 months of the implant placement. 2.3.3 Follow‐up After surgery, for a maintenance program, all patients followed an individual SPT. The ...

Materials & methods : A study on peri‐implant co...

Where a deficient posterior alveolar ridge and increased pneumatization of the maxillary sinus appeared, implants were inserted with simultaneous sinus floor augmentation (one‐step procedure) (osteotome technique, or lateral window technique) or after a previous sinus floor augmentation with bone grafting (two‐step procedure). Sites that exhibited localized horizontal bone...

Materials & methods : A study on peri‐implant co...

Successful tissue integration was examined using predefined criteria of success, as follows: Absence of persistent subjective complaints, such as pain, foreign body sensation and/or dysesthesia. Absence of implant mobility. Absence of continuous radiolucency around the implant. Implant prosthesis functional loading ≥1 year. Absence of exude or suppuration at acupressure o...

Materials & methods : A study on peri‐implant co...

2.2 Clinical parameters Periodical clinical examinations assessed before treatment and during follow‐up were recorded. Clinical parameters at baseline and after prosthesis positioning were used as a reference of development of peri‐implant disease. Based on the suggestion of Mombelli and Lang, and confirmed by the successive EWP consensus workshops published in 2008, 2011, and 2012, peri...

Materials & methods : A study on peri‐implant co...

This is a retrospective cohort study started from the analysis of clinical records of patients referring to private dental practices in central Italy (AP) treated between February 1998 and December 2002 by three different operators, and then included into a follow‐up program. We followed the Strengthening the Reporting of OBservational studies in Epidemiology (STROBE) guidelines for an accurate ...

Introduction : A study on peri‐implant complicat...

INTRODUCTION Implant‐prosthetic rehabilitation is a clinical procedure used to solve cases of partial or total edentulism. A functioning implant may be subject to plaque‐associated biological complications, such as mucositis and peri‐implantitis. Peri‐implant mucositis has been described as a reversible inflammatory lesion of the peri‐implant mucosa, whilst peri‐implantitis also desc...

A retrospective cohort study on peri‐implant com...

A retrospective cohort study on peri‐implant complications in implants up to 10 years of functional loading in periodontally compromised patients   Abstract Background Prevalence of peri‐implantitis is directly proportional to the time of functional loading. The aim of this retrospective study was to assess the survival and success rates as well as the incidence of peri‐implantitis ...

CONCLUSIONS : Comparison of 6‐mm and 11‐mm den...

CONCLUSIONS The present study found no significant difference between the clinical performance, including peri‐implant bone level changes and implant survival, of implants with 6 mm and 11 mm lengths, inserted in minimally resorbed edentulous spaces in the posterior maxilla and mandible, during a 5‐year follow‐up period. AUTHOR CONTRIBUTIONS Felix L. Guljé: Conceptualization (eq...

DISCUSSION : Comparison of 6‐mm and 11‐mm dent...

No analysis was performed if there was a possible difference in outcomes between the different centers. One reason is that the number of patients was not equally divided between the centers, making exploration for significant differences hardly reasonable. Next to this, randomization was performed using a block randomization sequence to provide equal distribution of subjects treate...

DISCUSSION : Comparison of 6‐mm and 11‐mm dent...

In the publication of Thoma et al. (2018), it was mentioned that there was 2% peri‐implantitis in the 6‐mm group and 0% in the longer‐implant group. Guljé et al. (2019) observed no peri‐implantitis in either groups. These numbers are low and very much alike the present study, although it should be noted that these studies used a slightly different definition of peri‐impl...

DISCUSSION : Comparison of 6‐mm and 11‐mm dent...

Thoma et al. (2018) reported a mean marginal bone level change of −0.12 ± 0.54 in the 6‐mm group and −0.18 ± 0.96 in the group with longer implants, without a significant difference between the groups. Guljé et al. (2019) reported a mean marginal bone level change of −0.12 ± 0.36 mm and −0.14 ± 0.63 mm in the 6‐mm group and the 11‐mm group, respectively, without ...

DISCUSSION : Comparison of 6‐mm and 11‐mm dent...

DISCUSSION Both 6‐mm short implants and 11‐mm conventional length implants performed well to support a fixed denture prosthesis in the posterior region of maxilla and mandible. A high implant survival rate, limited peri‐implant bone change, healthy peri‐implant soft tissues and limited biological and technical complications were noticed during the 5‐year functional period. There was a ...

Table 4. Number of technical complications at impl...

Table 4. Number of technical complications at implant level and patient level (between brackets) during 5 years of follow‐up   6‐mm group n implants = 97 (npatients = 46) 11‐mm group n implants = 86 (npatients = 39) Fracture of provisional restoration 3 (3) 3 (3) Fracture of definitive restoration 0 (0) 0 (0) Fracture of veneering 0 (0)...

Table 3. Clinical measures of implants

Table 3. Clinical measures of implants with plaque (in percentages), implants with bleeding on probing (in percentages) and mean (±SD) probing depth at implant level (in mm) at T0 (placement and loading of provisional restoration) and at T60 (5‐year follow‐up after loading of provisional restoration), and p‐value of differences between the groups at both evaluation periods     ...

Table 2. Mean value (in mm), standard deviation (S...

Table 2. Mean value (in mm), standard deviation (SD), and frequency distribution in (number and percentages) of marginal bone change between loading and 5 years in function   6‐mm group (n = 94) 11‐mm group (n = 80) mean bone change (SD) +0.01 (0.45) −0.12 (0.93) bone loss>−2.0 down 1 (1.1%) 6 (7.5%) bone loss>−2.0 up to and including −1.5 1 (1.1...

Table 1. Baseline characteristics

Table 1. Baseline characteristics of the 6‐mm group (49 participants with 108 implants) and the 11‐mm group (46 participants with 101 implants)   Group 6‐mm Group 11‐mm Mean age in years 55 ± 9, range 26–69 54 ± 10, range 34–70 Gender (number male/female) 21/28 27/19 Received a 2‐implant restoration 39 37 Received a 3‐implant restorati...

Results : Comparison of 6‐mm and 11‐mm dental ...

Forty‐nine patients were randomized to receive 6‐mm implants (test group) and 46 patients to receive 11‐mm implants (control group). The baseline characteristic of the patients is depicted in Table 1. A flow‐diagram from enrollment to 5‐year follow‐up can be found in Figure 3. A total of 209 implants were inserted: 108 implants in the 6‐mm group and 101 implants in the 11‐mm group....

Material & methods : Comparison of 6‐mm and 11...

2.4 Statistical analysis The number of patients required per group was calculated after assuming a two‐sided hypothesis to be rejected if the p‐value was below 5% and with a power of 80%. Primary outcome was mean peri‐implant bone level change, measured per implant, and a mean difference of 0.5 mm (standard deviation 0.8 mm) was chosen as a meaningful level of difference to be detected. ...

Material & methods : Comparison of 6‐mm and 11...

2.3 Outcome Evaluated parameters were: Implant failure (noted at any time throughout the 5‐year follow‐up period); Presence of plaque, probing depth (PPD) and bleeding on probing (BoP) was measured on four sites (mesial, distal, buccal, and lingual) around the implant (measured at time of provisional restoration, at time of definitive restoration and at annual follow‐up visits); Ra...

Material & methods : Comparison of 6‐mm and 11...

2.2 Surgical and prosthetic procedures To be included in the study, participants had to have an edentulous space during at least 4 months, spanning 2–3 teeth in the posterior maxilla or mandible and presence of natural teeth, partial prosthesis and/or implants in the opposite jaw in contact with the planned bridge. Patients also had to be able to receive an 11 mm long and 4 mm wide dental im...

Figure 2b. Five‐year follow‐up photograph of p...

Figure 2b. Five‐year follow‐up photograph of patient with two 11‐mm implants

Figure 2a. Five‐year follow‐up radiograph of p...

Figure 2a. Five‐year follow‐up radiograph of patient with two 11‐mm implants

Figure 2. Five‐year follow‐up of patient with ...

Figure 2. Five‐year follow‐up radiograph (a) and clinical photograph (b) of patient with two 11‐mm implants

Figure 1b. Five‐year follow‐up clinical photog...

Figure 1b. Five year follow‐up clinical photograph of patient with two 6 mm implants

Figure 1a: Five‐year follow‐up radiograph of p...

Figure 1a. Five‐year follow‐up radiograph of patient with two 6‐mm implants

Figure 1: patient with two 6‐mm implants

Figure 1. Five‐year follow‐up radiograph (a) and clinical photograph (b) of patient with two 6‐mm implants Figure 1. Five‐year follow‐up radiograph (a) and clinical photograph (b) of patient with two 6‐mm implants

Material & methods : Comparison of 6‐mm and 11...

2 MATERIAL AND METHODS 2.1 Study design The study outline has been described before in the 1‐year report of Guljé et al. (2013) and the 3‐year report of Zadeh et al. (2018). Inclusion/exclusion criteria, treatment and evaluation procedures are described in detail in these publications. The present report has been prepared in accordance with guidelines outlined in the CONSORT statement for...

Comparison of 6‐mm and 11‐mm dental implants i...

Comparison of 6‐mm and 11‐mm dental implants in the posterior region supporting fixed dental prostheses: 5‐year results of an open multicenter randomized controlled trial First published: 06 October 2020 | https://doi.org/10.1111/clr.13674 Abstract Objective The aim of this multicenter, randomized controlled trial was to compare the clinical and radiographic outcomes of 6‐mm or 11...

Definisi kasus & pertimbangan diagnosa : Penyakit ...

Bagaimana kita mendefinisikan kasus peri‐implantitis dalam keadaan pendidikan dan praktek sehari-hari? Diagnosa peri‐implantitis membutuhkan: keberadaan pendarahan dan/ atau penanahan dengan probing lembut. Peningkatan kedalaman probing bila dibandingkan dengan pemeriksaan sebelumnya. Keberadaan penyusutan tulang di luar perubahan tingkat tulang kresta yang diperoleh dari pemodelan ula...

Definisi kasus & pertimbangan diagnostik : Penyaki...

Definisi kasus dan karakteristik peri-implant saras, mukositis peri-implant, dan peri-implantitis berikut harus dilihat dalam konteks beberapa faktor pembaur tersembunyi. Diketahui bahwa tidak ada implant generik dan bahwa ada banyak desain implant dengan karakteristik permukaan, protokol bedah dan pembebanan yang berbeda. Tingkat pemodelan ulang fisiologi pasca pemasangan implant dapat berbeda...

Kekurangan jaringan lunak & jaringan keras : Penya...

Apa faktor utama yang berkaitan dengan kekurangan jaringan lunak & jaringan keras pada tempat yang akan dipasangi implant? Proses penyembuhan pasca kehilangan gigi marakke penyusutan matra proses alveolar / punggungan alveolar yang menggambarkan kekurangan jaringan lunak dan jaringan keras. Kekurangan yang lebih besar dapat terjadi di tempat yang terpapar faktor-faktor berikut: hilangnya duku...

Peri-implantitis : Penyakit dan ketentuan peri‐i...

What is peri‐implantitis? Peri-implantitis adalah kondisi patologi yang berhubungan dengan plak atau gadhel, yang terjadi pada jaringan di sekeliling implant gigi, ditandai dengan peradangan pada mukosa peri-implant, dan selanjutnya diikuti dengan kehilangan tulang pendukung progresif. Apa buktinya gadhel / biofilm merupakan faktor etiologi utama untuk terjadinya peri‐implantitis? ...

Mukositis peri‐implant : Penyakit & ketentuan pe...

Apa ciri klinis mukositis peri-implant? Ciri klinis utama mukositis peri-implant adalah perdarahan kala probing lembut. Eritema, bengkak, dan / atau nanah juga bisa muncul. Apakah mukositis peri‐implant bisa ada tanpa tanda-tanda klinis peradangan? Tanda-tanda klinis peradangan dibutuhkan untuk diagnosa mukositis peri-implant. Bagaimana kedalaman probing berkaitan dengan pengenal...

Peri-implant saras : Penyakit dan ketentuan peri...

Peri-implant saras : Penyakit dan ketentuan peri‐implant Apa ciri klinis tempat peri-implant yang saras? Tempat kedudukan peri-implat yang saras dicirikan dengan erithema, pendarahan kala  probing, pembengkakan dan nanah. Apa perbedaan klinis utama antara peri implant yang saras dan jaringan periodontal? Dalam keadaan saras, tidak ada perbedaan yang nampak antara jaringan peri‐imp...

Pendahuluan : Penyakit dan ketentuan peri‐implan...

Tujuan Workgroup 4 adalah untuk menyajikan penggolongan tentang penyakit dan ketentuan peri-implant. Lima karya tulis posisi yang menjelaskan ciri peri-implant saras, mukositis peri-implant, peri-implantitis, kekurangan jaringan lunak, kekurangan jaringan keras, penentuan kasus, dan pertimbangan diagnostik disiapkan sebelum lokakarya. Dalam menyiapkan laporan konsensus mengenai kr...

Penyakit peri-implant dan ketentuan-ketentuannya

Laporan konsensus kelompok kerja 4 tahun 2017 Lokakarya Buana Tentang Penggolangan Penyakit Periodontal dan Peri-implant Beserta Ketentuan-Ketentuannya Abstrak Penggolongan untuk penyakit peri-implant dan ketentuannya disajikan dalam lokakarya tersebut. Pertanyaan berfokus pada ciri peri‐implant yang saras, mukositis peri‐implant, peri‐implantitis, dan di sini diwedhar pula kekurangan ja...

Perbedaan utama antara peri-implant saras & jaring...

Perbedaan utama antara peri-implant saras & jaringan periodontal Perangkat implant tidak punya struktur pilah yang dipunyai oleh gigi seperti sementum akar, ligamen periodontal, dan tulang bundel (proper tulang alveolar). Bundel serat dento-alveolar dan dento-gingiva menghubungkan jaringan lunak dengan gigi (sementum akar), sementara tidak ada bundel serat yang terlihat pada jaringan peri-imp...

Jaringan tulang di sekeliling implant

Jaringan tulang di punggungan edentula Dalam suatu penelitian yang melibatkan sebagian subyek yang tidak bergigi, biopsi jaringan keras diambil sampelnya dari rahang atas dan rahang bawah dengan menggunakan bor trephine. Jaringan tulang ditemukan mencakup campuran sebagian besar tulang lamelar (46%) dan sumsum tulang (23%) dengan lebih sedikit jumlah jaringan fibrosa (12%) dan osteoid (4%). Su...

Mukosa berkeratin : peri-implant saras

Mukosa berkeratin Mukosa keratin adalah sebutan yang digunakan untuk menggambarkan mukosa pengunyahan yang terdapat di banyak tempat kedudukan implant tetapi tidak selalu terdapat di semua tempat kedudukan implant. Mukosa keratin memanjang dari tepi mukosa peri-implant ke mukosa lapisan (oral) yang dapat digerakkan. Mukosa keratin terdiri dari lamina propria (jaringan ikat fibrosa yang mengandung...

Pengukuran tulang : kesarasan peri-implant

Pengukuran tulang (bone sounding) Bone sounding atau transmucosal sounding (TS) adalah pengukuran yang digunakan untuk menentukan ketinggian seluruh cuff (manset) jaringan lunak  pada berbagai kelompok gigi dan implant. Matra mukosa peri-implan dan gingiva pada letak gigi yang berdekatan dipelajari dengan pengukuran klinis yang dilakukan terutama pada subjek edentulous sebagian yang telah dirawa...

Jaringan peri-implant dalam kesarasan klinis : kes...

Jaringan peri-implant dalam kesarasan klinis Gingiva dan mukosa peri‐implant dan perlekatannya (segel) secara konsisten ditantang oleh lingkungan mulut, termasuk paparan mikroorganisme dalam biofilm yang ada pada gigi dan permukaan implant. Pada mukosa (dan gingiva) peri-implant normal secara klinis, tanggapan inang yang terus-menerus meliputi kejadian vaskular dan seluler. Dengan demikian, str...

Dimensi mukosa peri-implant : peri-implant saras

Penelitian pada sato Dimensi mukosa peri-implant, yang sering disebut lebar atau matra biologis, diperiksa dalam biopsi terutama diperoleh dari studi pada pada waung. Pengukuran semacam itu mengungkapkan bahwa lebar jaringan lunak tertentu bisa dibutuhkan untuk menutup tulang peri-implant. Penelitian ini mengacu pada panjang epitel (dari margin mukosa peri-implant ke bagian apikal dari epitel per...

Morfogenesis pelekatan mukosa : kesarasan peri-imp...

Pembentukan pelekatan mukosa dipelajari pakai model waung. Perangkat implant one-piece dipasang di rahang waung pada bagian yang yang tidak ada giginya. Penyembuhan dipantau dengan menggunakan pemeriksaan biopsi pakai mikroskop cahaya dengan interval yang berbeda selama periode 3 bulan. Pada fase purwa luka antara implant dan jaringan ikat yang dipotong, bekuan / koagulum fibrin terbentuk. Ini ...

Mukosa peri‐implant: kesarasan peri-implant

Mukosa peri-implant Sebagian besar info tentang fitur struktural mukosa peri-implant sinangkan dari penelitian sato menggunakan model waung. Dalam penelitian tersebut, implant dipasang di punggungan yang tidak bergigi (alternatif, soket segar bekas gigi yang baru dicabut), bagian tulang luar yang ditutupi dengan mukosa pengunyahan. Ini juga menunjukkan bahwa mukosa peri‐implant yang sembuh pada...

Pendahuluan: kesarasan peri‐implant

Pendahuluan: kesarasan peri‐implant Jaringan peri‐implant adalah jaringan yang terbentu di sekeliling implant gigi yang ter-osseointegrasi. Jaringan tersebut dibagi menjadi kompartemen jaringan lunak dan jaringan keras. Kompartemen jaringan lunak ditandai dengan “mukosa peri-implant” dan terbentuk selama proses penyembuhan luka pasca pemasangan implant / abutment. Kompartemen jaringan k...

Kesarasan peri-implant

Abstrak Tujuan Tujuan penelitian adalah untuk menemukan ciri klinis dan ciri histologi jaringan peri-implant dalam keadaan saras dan menggambarkan antarmuka mukosa-implant. Nilai penting Pengertian tentang ciri jaringan peri-implant yang saras memudahkan pengenalan penyakit (yaitu, berangkat dari keadaan saras). Temuan Mukosa peri-implan yang saras, pada tataran mikroskopis, terd...

TABEL 1. t p50, SD, minimum (min) dan maximum (max...

  n p50 Mean SD Min. Max. Titanium             CD3 7 928 2,483 2,395 34 6,215 CD20 7 179 477 634 2 1,663 CD68 7 431 489 435 5 1,032 CD138 7 2,663 4,612 7,985 11 22,340 Ceramic             CD3 8 2,915 3,755 2,241 2,324 8,980 CD20 8 533 1,165 1,212 340 3,283 CD68 ...

Gambar 3. Biopsi diambil dari jaringan di seliling...

Gambar 3. Biopsi diambil dari jaringan disekeliling implant keramik & titanium menunjukkan kesamaan sebaran numerik populasi sel (CD3, CD20, CD68, CD138). Jumlah sel setiap antibody dalam peri‐implantitis di sekeliling implant keramik (biru) dan implant titanium (hijau)

Gambar 2. Biopsi diambil dari jaringan peri‐impl...

Gambar 2. Gambar 2. Biopsi diambil dari jaringan peri‐implantitis di seputar implant titanium dan implant keramik. Penodaan dilakukan pakai hematoxylin dan immunostaining terhadap CD3, CD20, CD68, dan CD138. Perbesaran ×5 dan ×40 berturut-turut.

Gambar 1. Analisis histomorfometrik yang dilakukan...

  Gambar 1. Analisis histomorfometrik dilakukan pada 20 ROI terpilih acak. ROI tersusun atas ukuran 500 × 800 µm dengan perbesaran ×15.5. Gambar ROI diambil dan sel-sel positif pada ROI dihitung pakai ImageJ. Weton ditinjauoleh seorang peneliti histologi terlatih (JM)  

Wedharan : Susunan imunohistologi jaringan yang te...

Selain itu, tanggapan inang dan salingpengaruh antara garis keturunan makrofag limfosit dan makrofag monosit serta pengaruh partikel nano dan partikel mikro pada biofilm mikroba dan pelepasan sitokin dalam peradangan peri-implant tidak dijelaskan dan penelitian di masa depan dapat menjelaskan lebih banyak dalam pawedharan etiologi. Dalam penelitian ini, dilakukan perbandingan histologi pertama le...

Wedharan : Susunan imunohistologi jaringan yang di...

Karena keragaman sebaran macam sel pada tataran pasien sudah konangan, weton penelitian kala ini dapat menyarankan tanggapan kekebalan yang terkait dengan parameter untuk pasien tertentu seperti susunan biofilm implant / mikrobiome oral, ciri permukaan implant yang berbeda, fitur anatomi yang berbeda seperti mutu tulang dan keadaan jaringan lunak, jalur etiologi yang berbeda dan / atau gabungan ja...

Wedharan : Susunan imunohistologi jaringan yang di...

Wedharan Susunan seluler jaringan dengan peri-implantitis di seputar implant berbasis zirkonia belum pernah dijelajahi sebelumnya. Salingpengaruh pilah antara sel-sel radang dalam jaringan dengan peri-implantitis dan dampaknya pada kerusakan osseous peri-implant sehubungan dengan bahan implant masih belum diketahui. Studi perintis ini menunjukkan bahwa ada penampilan histologi serupa lesi peri-im...

Weton : Komposisi imunohistologi jaringan yang dip...

Biopsi jaringan peri-implant diambil dari 15 pasien (berusia 34 hingga 88 tahun, enam laki-laki / sembilan perempuan) dengan peri-implantitis parah (delapan implant keramik, tujuh implant titanium) (lihat Tabel S1 dalam Jurnal Periodontologi online). Keberadaan makrofag, Limfosit-B, Limfosit-T, dan sel plasma diidentifikasi dalam semua sampel. Mikrograf yang menggambarkan lesi peri-implantitis unt...

Bahan & metode : Komposisi imunohistologi jaringan...

2.4 Analisis imunohistokimia Irisan-irisan biopsi dilepas lilinnya dan diinkubasi dalam larutan pengambilan antigen DIVA pada suhu 60°C semalam. Irisan tersebut diinkubasi dengan antibodi primer selama 30 menit diikuti dengan inkubasi dengan Envision HRP berlabel polimer selama 30 menit. Sel positif terdeteksi menggunakan substrat DAB. Antibodi yang dipilih adalah CD3 1:200 (limfosit-T), CD20 ...

Bahan & metode : Komposisi imunohistologi jaringan...

Penelitian ini disetujui oleh komite etik Pusat Medis Universitas Freiburg, Jerman (Ethik‑Kommission Albert‑Ludwigs‑Universität, Freiburg) No 337/04. Penelitian dilakukan seturut Deklarasi Helsinki tahun 1964, sebagaimana direvisi pada tahun 2013 dan dengan pedoman EQUATOR (Enhancing the QUAlity and Transparency Of health Research). Sebelum nglelarik, pasien menerima warta tentang tujuan p...

Pendahuluan : Komposisi imunohistologis jaringan y...

Implant oral memperbesar pilihan perawatan untuk mengganti gigi yang hilang dan sudah terbukti jadi, seperti yang ditunjukkan dalam tinjauan sistematik dengan tindak lanjut jangka panjang. Meskipun tingkat kelangsungan hidup tampak mitayani, peri-implantitis di sekitar implant gigi adalah tantangan dalam praktik sehari-hari, dengan kelumrahan sekitar 20%. Tingkat kelumrahan peri-implantitis sangat...

Komposisi imunohistologi peri‐implantitis yang t...

Latar belakang Tujuan penelitian perintis ini adalah klasifikasi hisologis jaringan lunak peri-implant yang meradang di sekitar implant keramik dibandingkan dengan implant titanium. Metode Jaringan peri-implant diambil dari 15 pasien (berusia 34 hingga 88 tahun, tujuh laki-laki / delapan perempuan) yang menderita peri-implantitis parah (delapan implant keramik, tujuh implant titanium). Sampel j...

Parameter pemasangan & tatalaksana implant gigi (2...

PEMASANGAN IMPLANT Pertimbangan prostetik untuk para pasien yang membutuhkan pemasangan implant harus meliputi peninjauan: Jumlah dan letak gigi yang hilang Jarak interarch (inter-lengkung) Jumlah, macam, dan letak implant yang akan dipasang Skema oklusal yang ada dan yang diusulkan Rancangan pemugaran yang direncanakan Teknik bedah didasarkan pada peninjauan pra-rawat dan macam implant...

Parameter pemasangan & tatalaksana implant gigi (1...

Akademi Periodontologi Amerika telah mengembangkan parameter pemasangan dan penatalaksanaan implant gigi berikut ini. Implant gigi adalah salah satu bentuk penggantian gigi yang telah diakui dan karenanya harus disajikan sebagai alternatif untuk penggantian gigi yang copot. Rencana perawatan yang komprehensif harus dikembangkan dengan berkonsultasi dengan semua pihak yang terlibat. Pasien harus di...

Case definitions & diagnostic considerations : Per...

How do we define a case of peri‐implantitis in day‐to‐day clinical practice and teaching situations? Diagnosis of peri‐implantitis requires: Presence of bleeding and/or suppuration on gentle probing. Increased probing depth compared to previous examinations. Presence of bone loss beyond crestal bone level changes resulting from initial bone remodeling. In the a...

Case definitions & diagnostic considerations : Per...

The following case definitions and characteristics of peri‐implant health, peri‐implant mucositis, and peri‐implantitis should be viewed within context of several potential confounding factors. It is known that there is no generic implant and that there are numerous implant designs with different surface characteristics, surgical and loading protocols. The degree of physiological remodeli...

Hard‐ & soft-tissue deficiencies : Peri‐implan...

What are the main factors associated with hard‐ and soft‐tissue deficiencies at potential implant sites? The healing process following tooth loss leads to diminished dimensions of the alveolar process/ridge representing hard‐ and soft‐tissue deficiencies. Larger deficiencies may occur at sites exposed to the following factors: loss of periodontal support, endodontic in...

Peri-implantitis : Peri‐implant diseases and con...

  What is peri‐implantitis? Peri‐implantitis is a plaque‐associated pathological condition occurring in tissues around dental implants, characterized by inflammation in the peri‐implant mucosa and subsequent progressive loss of supporting bone. What is the evidence for plaque/biofilm as a principal etiological factor for peri‐implantitis? There is evidence ...

Peri‐implant mucositis : Peri‐implant diseases...

What are the clinical characteristics of peri‐implant mucositis? The main clinical characteristic of peri‐implant mucositis is bleeding on gentle probing. Erythema, swelling and/or suppuration may also be present. Does peri‐implant mucositis exist in the absence of clinical signs of inflammation? Clinical signs of inflammation are necessary for a diagnosis of peri...

Peri-implant health : Peri‐implant diseases and ...

What are the clinical characteristics of a healthy peri‐implant site? In health, the peri‐implant site is characterized by absence of erythema, bleeding on probing, swelling and suppuration. What are the main clinical differences between healthy peri‐implant and periodontal tissues? In health, there are no visual differences between peri‐implant and periodontal t...

Introduction : Peri‐implant diseases and conditi...

The objective of Workgroup 4 was to present a classification on peri‐implant diseases and conditions. Five position papers describing the characteristics of peri‐implant health, peri‐implant mucositis, peri‐implantitis, soft and hard tissue deficiencies and case definitions and diagnostic considerations were prepared prior to the workshop. In preparing this consensus report regarding...

Peri‐implant diseases and conditions

Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri‐Implant Diseases and Conditions Abstract A classification for peri‐implant diseases and conditions was presented. Focused questions on the characteristics of peri‐implant health, peri‐implant mucositis, peri‐implantitis, and soft‐ and hard‐tissue deficiencies were addressed. ...

Major differences between healthy peri-implant & p...

The implant device lacks tooth characteristic structures such as root cementum, periodontal ligament, and bundle bone (alveolar bone proper). The dento‐alveolar and the dento‐gingival fiber bundles connect the soft tissues with the tooth (root cementum), while no such fiber bundles are apparent in the peri‐implant tissues. At periodontally healthy sites, the margin of the gingiva follow...

Bone tissue around implants

Bone tissue in the edentulous ridge In a study involving partially edentulous subjects, hard tissue biopsies were sampled from the maxilla and the mandible with the use of trephine drills. The bone tissue was found to include a blend of mainly lamellar bone (46%) and bone marrow (23%) with less amounts of fibrous (12%) and osteoid (4%) tissue. Bone marrow was the dominant tissu...

Keratinized mucosa : peri-implant health

KERATINIZED MUCOSA (KM) Keratinized mucosa is a term used to describe the masticatory mucosa that is present at many, but not all, implant sites. Keratinized mucosa extends from the margin of the peri‐implant mucosa to the movable lining (oral) mucosa. Keratinized mucosa is comprised of a lamina propria (fibrous connective tissue that contains fibroblasts and equal amounts of ty...

Bone sounding : peri-implant health

BONE SOUNDING Bone sounding or transmucosal sounding (TS) is a measurement that is used to determine the height of the entire soft tissue cuff at various groups of teeth and implants. The dimensions of the peri‐implant mucosa and the gingiva at adjacent tooth sites was studied by clinical measurements performed mainly in partially edentulous subjects who had been treated with im...

Peri-implant tissues in clinical health : peri-imp...

PERI‐IMPLANT TISSUES IN CLINICAL HEALTH The gingiva and the peri‐implant mucosa and their adhesion (seal) are consistently challenged by the oral environment, including the steady exposure to microorganisms in the biofilm present on the tooth and implant surfaces. In the clinically normal peri‐implant mucosa (and gingiva), the continuous host response includes both vascular ...

Dimension of the peri-implant mucosa : peri-implan...

Animal studies The dimension of the peri‐implant mucosa, often called the biological width or dimension, was examined in biopsies mainly obtained from studies in dogs. Such measurements disclosed that a certain width of soft tissue may be required to cover the peri‐implant bone. The studies referred to the length of the epithelium (from the peri‐implant mucosa margin to the...

Morphogenesis of the mucosal adhesion : peri-impla...

The formation of the mucosal adhesion was studied in a dog model. One‐piece implant devices were placed in the edentulous mandible of dogs, and healing was monitored using light microscopic examination of biopsies sampled at different intervals during a 3‐month period. In the initial phase of the wound between the implant and cut connective tissue, a fibrin clot/coagulum formed that was inf...

Peri‐implant mucosa: peri-implant health

PERI‐IMPLANT MUCOSA Most information regarding the structural features of the peri‐implant mucosa is derived from animal studies using dog models. In such studies implants were placed in the edentulous ridge (alternatively, the fresh extraction socket), the outer osseous part of which was covered with masticatory mucosa. It was also shown that the healed peri‐implant mucosa on the buccal a...

Introduction: Peri‐implant health

Peri‐implant tissues are those that occur around osseointegrated dental implants. They are divided into soft and hard tissue compartments. The soft tissue compartment is denoted “peri‐implant mucosa” and is formed during the wound healing process that follows implant/abutment placement. The hard tissue compartment forms a contact relationship to the implant surface to secure implant stab...

Peri‐implant health

Abstract Objective The aim is to define clinical and histologic characteristics of peri‐implant tissues in health and describe the mucosa–implant interface. Importance An understanding of the characteristics of healthy peri‐implant tissues facilitates the recognition of disease (i.e., departure from health). Findings The healthy peri‐implant mucosa is, at the microscopic ...

TABLE 1. t p50, SD, minimum (min) and maximum (max...

  n p50 Mean SD Min. Max. Titanium             CD3 7 928 2,483 2,395 34 6,215 CD20 7 179 477 634 2 1,663 CD68 7 431 489 435 5 1,032 CD138 7 2,663 4,612 7,985 11 22,340 Ceramic             CD3 8 2,915 3,755 2,241 2,324 8,980 CD20 8 533 1,165 1,212 340 3,283 CD68 8 519 529 25...

Gambar 4. Plot tumpuk (stacked plot) menunjukkan r...

Gambar 4. Plot tumpuk (stacked plot) menunjukkan respon kekebalan spesifik pasien. Sebaran persentase sel diwarnai dengan CD3, CD20, CD68, dan CD138 untuk setiap pasien (pasien 1 sampai 15)

Figure 4. Stacked plot demonstrated a patient‐sp...

Figure 4. Stacked plot demonstrated a patient‐specific immune response. Percentage distribution of cells stained with CD3, CD20, CD68, and CD138 for each patient (patients 1 to 15)

Figure 3. Biopsies derived from tissue around cera...

Figure 3. Biopsies derived from tissue around ceramic and titanium implants demonstrated the same numerical distribution of cell population (CD3, CD20, CD68, CD138). Cell count of each antibody in peri‐implantitis around ceramic (blue) and titanium (green) implants

Figure 2. Biopsies retrieved from peri‐implantit...

Figure 2. Biopsies retrieved from peri‐implantitis tissue around titanium and ceramic implants. Figure 2. Biopsies retrieved from peri‐implantitis tissue around titanium and ceramic implants. Staining was performed using hematoxylin and immunostaining against CD3, CD20, CD68, and CD138. Magnification ×5 and ×40, respectively.  

Figure 1. Histomorphometric analysis performed in ...

Figure 1. Histomorphometric analysis was performed in 20 randomly selected ROIs (Region of Interests). Figure 1. Histomorphometric analysis was performed in 20 randomly selected ROIs (Region of Interests). The ROIs comprised a size of 500 × 800 µm at magnification of ×15.5. Pictures of the ROIs were taken and positive cells in the ROIs were counted using ImageJ. The results were evaluated by...

Discussion : Immunohistological composition of per...

Furthermore, the host‐response and interaction between lymphocyte‐ and monocyte‐macrophage lineage as well as the influence of nano‐ and microparticles on the microbial biofilm and cytokine release in peri‐implant inflammation is not elucidated and future studies could shed more light on the etiological discussion. Within this study, the first histological comparison of human peri‐imp...

Discussion : Immunohistological composition of per...

Since variations regarding cell‐type distribution on the patient level were detected, the present results may suggest an immune response associated with patient‐specific parameters like implant biofilm/oral microbiome composition, different implant surface characteristics, different anatomical features like bone quality and soft tissue condition, different and/or combined etiology pathways and...

Discussion : Immunohistological composition of per...

The cellular composition of tissue with peri‐implantitis around zirconia‐based implants has never been explored before. The specific interaction of inflammatory cells in tissue with peri‐implantitis and their impact on peri‐implant osseous breakdown with regard to the implant material is still unknown. The present pilot study demonstrated that there is a similar histological appearance of ...

Results : Immunohistological composition of peri...

Biopsies of the peri‐implant tissue were retrieved from 15 patients (aged 34 to 88 years, six males/nine females) with severe peri‐implantitis (eight ceramic implants, seven titanium implants) (see Table S1 in online Journal of Periodontology). The presence of macrophages, B‐Lymphocytes, T‐Lymphocytes, and plasma cells was identified in all samples. Micrographs illustratin...

Materials & methods : Immunohistological compositi...

2.4 Immunohistochemical analysis Sections were de‐waxed and incubated in DIVA antigen retrieval solution at 60°C overnight. The sections were incubated with a primary antibody for 30 minutes followed by incubation with Envision HRP labeled polymer for 30 minutes. Positive cells were detected using DAB substrate. The chosen antibodies were CD3 1:200 (T‐l...

Materials & methods : Immunohistological compositi...

The study was approved by the ethics committee of the University Medical Center Freiburg, Germany (Ethik‐Kommission Albert‐Ludwigs‐Universität, Freiburg) No 337/04. This study was performed in accordance with the Helsinki Declaration of 1964, as revised in 2013 and with EQUATOR (Enhancing the QUAlity and Transparency Of health Research) guidelines. Before en...

Introduction : Immunohistological composition of p...

Oral implants enlarge the treatment options to replace missing teeth and have been proven to be successful as shown in systematic reviews with long‐term follow‐up. Although survival rates appear convincing, peri‐implantitis around dental implants is a challenge in daily practice, with a prevalence around 20%. The prevalence rate of peri‐implantitis is highly variable and seems to be affec...

Immunohistological composition of peri‐implantit...

Background Aim of the pilot study was the histologic classification of the inflamed peri‐implant soft tissue around ceramic implants (CI) in comparison with titanium implants (TI). Methods Peri‐implant tissue were retrieved from 15 patients (aged 34 to 88 years, seven males/eight females) with severe peri‐implantitis (eight CI, seven TI). The peri‐implant soft tissue samples were retrie...

Parameter on Placement and Management of the Denta...

IMPLANT PLACEMENT Prosthetic considerations for patients requiring implant placement should include evaluation of: Number and location of missing teeth; Interarch distance; Number, type, and location of implants to be placed; Existing and proposed occlusal scheme; Design of planned restoration. The surgical technique is based on the pretreatment evaluation and on the type of implant to ...

Parameter on Placement and Management of the Denta...

The American Academy of Periodontology has developed the following parameter on the placement and management of dental implants. Dental implants are a recognized form of tooth replacement and as such should be presented as an alternative for the replacement of missing teeth. A comprehensive treatment plan should be developed in consultation with all parties involved. Patients should be informed ab...

Model mukositis peri-implant eksperimental vs lesi...

Penelitian pada manusia Penelitian-penelitian eksperimental pada manusia telah mengevaluasi respons terhadap penumpukan biofilm 3 minggu, sesuai dengan kerangka kala penelitian gingivitis eksperimental oleh Löe et al., di mana reversibilitas lesi radang di seputar gigi ditunjukkan setelah reinstitusi kontrol biofilm setelah 3 minggu. Ada penelitian yang melaporkan biopsi manusia dari jaringan pe...

Tabel 2. Bukti untuk faktor sebagai indikator risi...

Indikator risiko Publiskasi Ringkasan Rasio  ganjil (95% CI), analisis multivariat Signifikansi Keberadaan biofilm plak Roos‐Jansaker et al. 218 subyek, 9 tahun sampai 14 tahun tindak lanjut, analisis multivariat  1.9 (1.2 –2.9) P = 0.004 Skor plak: buruk = skor plak median  1 < x < 2 Ferreira et al. 212 subyek semua non‐smokers, 6 bulan sampai 5 tah...

Persamaan & perbedaan antara indikator / faktor ri...

Persamaan & perbedaan antara indikator / faktor risiko untuk penyakit periodontal vs mukositis peri-implant Tinjauan sistematis terbaru merinkes indikator risiko potensial untuk mukositis peri-implant dan mengidentifikasi penumpukan biofilm dan merokok sebagai indikator risiko. Selain itu, penelitian lintas bagian menunjukkan bahwa skor plak merupakan indikator risiko mukositis peri-implant den...

Indikator / faktor risiko untuk mukositis peri-imp...

Desain prostesis yang didukung implant Aksesibilitas untuk penghapusan biofilm di sekeliling prostesis yang didukung implant memainkan peran penting dalam upaya pencegahan dan penatalaksanaan penyakit peri‐implant. Implant dengan margin restorasi supramukosa metokke penurunan kedalaman probing yang jauh lebih besar setelah perawatan mukositis peri-implant dibandingkan implant dengan margin rest...

Indikator / faktor risiko untuk mukositis peri-imp...

Pada pasien edentula sebagian, mukositis peri-implant pra-ada yang disertai dengan kurangnya kepatuhan pada SIT punya hubungan dengan tingkat kejadian peri-implantitis yang lebih tinggi selama periode tindak lanjut 5 tahun. Weton penelitian itu metokke tingkat kejadian peri-implantitis 5 tahun sebesar 18.0% pada kelompok pasien dengan SIT dan 43.9% dalam kelompok tanpa SIT. Analisis regresi logi...

Indikator / faktor risiko untuk mukositis peri-imp...

Kebersihan mulut Weton penelitian klinis penampang telah dengan jelas menunjukkan bahwa penumpukan biofilm berkaitan dengan adanya mukositis peri-implant di seputar implant gigi yang ter-osseointegrata. Ferreira et al melaporkan tentang 212 pasien yang dirawat dengan tiga sistem implant yang berbeda dan didiagnosis dengan mukositis peri-implant. Semua implant telah berfungsi untuk jangka wayah mu...

Indikator / faktor risiko untuk mukositis peri-imp...

Pada Lokakarya Buana sebelumnya tentang Periodontologi, definisi faktor risiko disetujui sebagai "faktor lingkungan, perilaku, atau biologis yang dikonfirmasi oleh urutan temporal, biasanya dalam studi longitudinal, yang jika ada, secara langsung meningkatkan peluang penyakit terjadi dan, jika tidak ada atau dihapus mengurangi peluang itu." Untuk mengidentifikasi faktor risiko yang sebenarnya, but...

Model mukositis peri-implant eksperimental vs lesi...

Penelitian eksperimental pada manusia dan sato telah menunjukkan bahwa penumpukan biofilm de novo memicu lesi radang dalam mukosa peri-implant dengan migrasi leukosit melalui epitel penghalang dan pembentukan infiltrat radang dengan peningkatan proporsi sel T dan sel B di dalam jaringan ikat yang berada dekat dengan epitel penghalang. Model sato Model mukositis peri-implant eksperimental telah...

Mukositis peri-implant yang dipicu biofilm bisakah...

Meskipun hubungan daruna-daruni antara akumulasi biofilm eksperimental dan pengembangan mukositis peri-implant eksperimental diklaim dalam dua penelitian yang disebutkan sebelumnya, kasus untuk hubungan daruna-daruni yang sebenarnya akan diperosa oleh bukti reversibilitas untuk tingkat pra-eksperimental kesarasan mukosa. Dalam penelitian oleh Salvi et al, GI di situs implant turun secara signifik...

Perubahan dari mukosa peri-implant saras jadi peri...

Mukosa peri-implant yang saras ditandai dengan adanya epitel oral yang meluas ke epitel penghalang non-keratin dengan lamina basal dan hemidesmosome yang menghadap ke permukaan implant atau abutmen. Dalam jaringan ikat yang berdekatan dengan penghalang epitel, ada infiltrat sel radang yang menyulihi pertahanan inang terhadap tantangan bakteri. Dalam kondisi mukosa peri-implant yang saras, epitel p...

Tabel 1. Persamaan & perbedaan antara gingivitis t...

    Gingivitis Mukositis peri‐implant Pengertian Peradangan gingival tanpa susut perlekatan periodontal Peradangan mukosa peri‐implant tanpa penyusutan tulang peri-implant berkelanjutan Tanda klinis Kemerahan, bengkak, dan perdarahan dengan probing lembut Kemerahan, bengkak, perdarahan dengan probing lembut, dan nanah Peradangan eksperimental pada manusia P...

Pengertian : Mukositis peri‐implant

Mukosa peri-implan telah didefinisikan dalam lokakarya sebelumnya sebagai lesi inflamasi mukosa yang mengelilingi implant endosseous tanpa kehilangan tulang peri-implant pendukung. Kriteria penting untuk pengertian mukositis peri-implant adalah peradangan pada mukosa peri-implant dan tidak adanya keropos tulang peri-implant marjinal yang berkelanjutan. Tanda klinis peradangan adalah pendarahan pad...

Bahan & metode : Mukositis peri‐implant

Pencarian literatur MEDLINE (PubMed) dan The Cochrane Library hingga dan termasuk 31 Juli 2016, dilakukan menggunakan strategi pencarian (peri-implant[All Fields] AND ("mucositis"[MeSH Terms] OR "mucositis"[All Fields])) OR (periimplant[All Fields] AND mucositis[All Fields]), memunculkan 224 karya kawidyan. Penelitian prospektif, retrospektif, dan lintas bidang dan karya tinjauan yang berfokus pad...

Pendahuluan : Peri‐implant mucositis

Penyakit peri-implant, termasuk peri-implant mucositis dan peri-implantitis, pertama kali didefinisikan dan dijelaskan pada Lokakarya Eropa Pertama tentang Periodontologi di Ittingen pada tahun 1993. Setelah itu, ada banyak lokakarya yang medhar definisi, kelumrahan, dan pengobatan penyakit ini. penyakit. Mucositis peri-implan dianggap sebagai prekursor peri-implantitis. Tujuan dari tinjauan narat...

Mukositis peri-implant

Tujuan Tinjauan naratif ini disiapkan untuk Lokakarya Buana 2017 Akademi Periodontologi Amerika dan Federasi Periodontologi Eropa untuk menanggapi pertanyaan-pertanyaan kunci terkait dengan kondisi klinis mukositis peri-implant, termasuk: definisi mukositis peri-implant, perubahan kesarasan peri-implant jadi lesi mukositis peri-implant yang diinduksi oleh biofilm, reversibilitas mukositis ...

Gambar 1. Peri-implant mucositis vs peri-implantit...

Gambar 1. Peri-implant mucositis vs peri-implantitis vs peri-implant health

Table 2. Evidence for factors as risk indicators f...

Risk indicator Publication Summary Odds ratio (95% CI), multivariate analysis Significance Plaque biofilm presence Roos‐Jansaker et al. 218 subjects, 9‐ to 14‐year follow‐up, multivariate analysis 1.9 (1.2 –2.9) P = 0.004 Plaque score: poor = median plaque score > 1 and 

Similarities & differences between risk indicators...

SIMILARITIES AND DIFFERENCES BETWEEN RISK INDICATORS/FACTORS FOR PERIODONTAL DISEASES VERSUS PERI‐IMPLANT MUCOSITIS A recent systematic review summarized potential risk indicators for peri‐implant mucositis and identified biofilm accumulation and smoking as risk indicators. In addition, a cross‐sectional study showed that plaque score was a risk indicator for peri‐implant mucositis in a...

Risk indicators / factors for peri-implant mucosit...

Design of implant‐supported prostheses Accessibility for biofilm removal around implant‐supported prostheses plays an important role in the prevention and management of peri‐implant diseases. Implants with supramucosal restoration margins yielded significantly greater reductions in probing depths following treatment of peri‐implant mucositis compared with those with submucosal restoration...

Risk indicators / factors for peri-implant mucosit...

In partially edentulous patients, pre‐existing peri‐implant mucositis in conjunction with lack of adherence to SIT was associated with a higher incidence of peri‐implantitis during a 5‐year follow‐up period. The outcomes of that study yielded a 5‐year incidence of peri‐implantitis of 18.0% in the group of patients with SIT and of 43.9% in the group without SIT, respectively. The ...

Risk indicators / factors for peri-implant mucosit...

Oral hygiene Outcomes of cross‐sectional clinical studies have clearly indicated that biofilm accumulation is associated with the presence of peri‐implant mucositis around osseointegrated dental implants. Ferreira et al. reported on 212 patients treated with three different implant systems and diagnosed with peri‐implant mucositis. All implants had been in function for a period ranging f...

Risk indicators / factors for peri-implant mucosit...

At a previous World Workshop on Periodontology the definition of a risk factor was agreed as, “an environmental, behavioral or biologic factor confirmed by temporal sequence, usually in longitudinal studies, which if present, directly increases the probability of a disease occurring and, if absent or removed reduces that probability.” To identify a true risk factor, prospective studies are req...

Experimental peri-implant mucositis models vs long...

Experimental studies in humans and animals have demonstrated that de novo biofilm accumulation results in an inflammatory lesion within the peri‐implant mucosa with migration of leukocytes through the barrier epithelium and the establishment of an inflammatory infiltrate with an increased proportion of T‐ and B‐cells in the connective tissue adjacent to the barrier epithelium. Animal mod...

Is biofilm-induced peri-implant mucositis a revers...

Although a cause–effect relationship between experimental biofilm accumulation and the development of experimental peri‐implant mucositis was claimed in the two studies mentioned previously, the case for a true cause–effect relationship would be strengthened by the proof of reversibility to pre‐experimental levels of mucosal health. In the study by Salvi et al., the GI at implant sites dr...

Conversion from healthy peri-implant mucosa to per...

Healthy peri‐implant mucosa is characterized by the presence of an oral epithelium extending into a non‐keratinized barrier epithelium with basal lamina and hemidesmosomes facing the implant or abutment surface. In the connective tissue adjacent to the epithelial barrier, inflammatory cell infiltrates representing the host's defense against the bacterial challenge are present. In healthy peri...

Table 1. Similarities and differences between biof...

  Gingivitis Peri‐implant mucositis Definition Gingival inflammation without periodontal attachment loss Peri‐implant mucosal inflammation in absence of continuous marginal peri‐implant bone loss Clinical signs Redness, swelling, and bleeding on gentle probing Redness, swelling, bleeding on gentle probing, and suppuration Experimental inflammation in humans I...

Definition : Peri‐implant mucositis

Peri‐implant mucositis has been defined in previous workshops as an inflammatory lesion of the mucosa surrounding an endosseous implant without loss of supporting peri‐implant bone. The important criteria for the definition of peri‐implant mucositis are inflammation in the peri‐implant mucosa and the absence of continuing marginal peri‐implant bone loss. The clinical sign of inflammation...

Materials & methods : Peri‐implant mucositis

A literature search of MEDLINE (PubMed) and The Cochrane Library up to and including July 31, 2016, was carried out using the search strategy (peri‐implant[All Fields] AND (“mucositis”[MeSH Terms] OR “mucositis”[All Fields])) OR (periimplant[All Fields] AND mucositis[All Fields]), resulting in 224 papers. Prospective, retrospective, and cross‐sectional studies and review papers focused...

Pendahuluan : Peri‐implant mucositis

Peri‐implant diseases, including peri‐implant mucositis and peri‐implantitis, were first defined and described at the First European Workshop on Periodontology in Ittingen in 1993. Following this, there have been numerous workshops addressing the definition, prevalence, and treatment of these diseases. Peri‐implant mucositis is considered to be the precursor of peri‐implantitis. The ob...

Peri‐implant mucositis

Objectives This narrative review was prepared for the 2017 World Workshop of the American Academy of Periodontology and European Federation of Periodontology to address key questions related to the clinical condition of peri‐implant mucositis, including: 1) the definition of peri‐implant mucositis, 2) conversion of peri‐implant health to the biofilm‐induced peri‐implant mucositis lesi...

Graft jaringan ikat (2)

Sebaliknya, ketika merawat dehisens jaringan lunak peri-implant, penggunaan CTG sangat dianjurkan, terlepas dari lebar atau ketebalan mukosa berkeratin. Sementara itu, pengganti graft autogen sering digunakan untuk meningkatkan ketebalan jaringan dan meminimalkan resesi mukosa pasca operasi selama penempatan implant segera atau pada pembukaan implant. Beberapa pendekatan pengambilan graft, sepert...

Wedharan: supraerupsi sebagai pertimbangan untuk r...

Tingkat rata-rata supraerupsi adalah 0.14 mm / bulan di semua subjek dan 0.22 mm / bulan dalam masa 6 bulan setelah ekstraksi. Ketebalan enamel pada permukaan oklusal gigi biasanya 1.0-1.5 mm. Temuan ini menunjukkan bahwa jumlah supraerupsi tidak dapat disesuaikan hanya dengan enameloplasty ketika gigi oposisi hilang selama lebih dari 1 tahun. Penempatan implant konvensional membutuhkan periode ...

Wedharan: supraerupsi sebagai pertimbangan untuk r...

Tingkat rata-rata supraerupsi adalah 0.14 mm / bulan pada semua subjek dan 0.22 mm / bulan dalam masa 6 bulan setelah ekstraksi. Ketebalan enamel pada permukaan oklusal gigi biasanya 1.0-1.5 mm. Temuan-temuan ini menunjukkan bahwa jumlah supraerupsi tidak dapat disesuaikan hanya dengan enameloplasty ketika gigi oposisi hilang selama lebih dari 1 tahun. Penempatan implant konvensional membutuhkan p...

Wedharan: supraerupsi sebagai pertimbangan untuk r...

Usia, kehilangan perlekatan, dan lengkungan telah dilaporkan dalam hubungannya dengan supraerupsi. Penelitian ini mengungkapkan bahwa kelumrahan supraerupsi dipengaruhi oleh macam kelamin, usia, dan jarak dari CEJ ke ABC. Perempuan punya tingkat kelumrahan supraerupsi yang lebih tinggi bila dibandingkan dengan laki-laki. Namun, jumlah dan tingkat supraerupsi cenderung lebih tinggi pada pria, meski...

Wedharan: supraerupsi sebagai pertimbangan untuk r...

  Wedharan Hilangnya gigi posterior bisa marakken perubahan posisi gigi oposisi seperti rotasi, kemiringan, dan supraerupsi. Beberapa penelitian telah menyelidiki prevalensi atau tingkat supraerupsi, tetapi tidak ada penelitian sebelumnya telah mengevaluasi tingkat supraerupsi. Penelitian ini mengukur perubahan di lokasi vertikal geraham kedua rahang atas sebelum dan sesudah mengekstraksi gigi ...

Weton: supraerupsi sebagai pertimbangan untuk rest...

Weton Penelitian ini mengevaluasi supraerupsi molar kedua rahang atas setelah ekstraksi gigi oposisi pada 65 pasien (30 wanita dan 35 pria). Usia rata-rata pasien adalah 53,88 tahun (rentang 22-77 tahun). Periode rata-rata dari radiograf pertama ke radiograf purna adalah 7.21 bulan (rentang 1.5-45 bulan) dan sebagian besar pasien (57 dari 65 pasien) menerima pemulihan implant dalam masa 12 bulan....

Analisis statistik: Supraerupsi sebagai pertimbang...

Data dievaluasi menggunakan SPSS versi 23 (IBM Corp., Armonk, NY, USA). Untuk analisis statistik, peserta dibagi menjadi pasangan kelompok menurut macam kelamin (30 wanita dan 35 pria), usia (48 subyek berusia < 60 tahun dan 17 subyek berusia ≥ 60 tahun), dan jarak dari CEJ ke ABC (< 2 mm dalam 32 subyek dan ≥ 2 mm dalam 33 subyek). Prevalensi supraerupsi dievaluasi pada setiap kelompok, dan ...

Material & method: Supraerupsi sebagai pertimbanga...

Study design Penelitian ini mengevaluasi supraerupsi dari molar kedua rahang atas setelah ekstraksi gigi yang berlawanan. Pasien yang menjalani penempatan implant di lokasi molar kedua mandibula antara September 2008 dan September 2016 dan memiliki radiograf panorama sebelum ekstraksi molar kedua mandibula dan ketika pemasangan prostesis implant pada molar kedua mandibula disertakan. Data dikum...

Pendahuluan : Supraerupsi sebagai pertimbangan unt...

Supraerupsi gigi oposisi merupakan suatu tantangan ketika memulihkan gigi yang hilang. Gigi terus erupsi perlahan selama hidup bahkan setelah bidang oklusal telah didekati, dan tingkat erupsi dapat meningkat jika kontak dengan gigi oposisi hilang. Hilangnya gigi posterior dapat mendatangkan perubahan 3 dimensi dalam posisi gigi yang berlawanan, seperti supraerupsi, rotasi, dan tipping. Tidak semua...

Abstrak: Supraerupsi sebagai pertimbangan untuk re...

Tujuan Tujuan penelitian ini adalah untuk membandingkan prevalensi, jumlah, dan tingkat supraerupsi molar kedua maksila berdasarkan macam kelamin, usia, dan lelarah periodontitis. Metode Data dikumpulkan secara retrospektif dari grafik dan radiograf panorama dari 65 pasien yang direncanakan untuk menjalani penempatan implant di lokasi molar kedua mandibula. Jumlah supraeruption dari molar ked...

Modifikasi implant berbasis obat

Strategi-strategi pelapisan permukaan implant yang baru guna meningkatkan oseointegrasi implant melibatkan pengembangan kemampuan implant dibebani obat agar bisa secara lokal efektif menyasar gangguan tulang di seputar implant gigi. Umpamanya, agen anti resorptif (contohnya, bisfosfonat) dan agen anabolik (contohnya, strontium ranelate dan statins) bisa meningkatkan oseointegrasi implant dalam tul...

Kapasitas implant menanggung beban

Kapasitas implant menanggung beban dipengaruhi oleh beberapa faktor, termasuk jumlah implant, ukuran implant, angulasi dan tatanan posisi implant, dan kualitas antarmuka tulang-implant. Jumlah implant gigi yang dipakai akan memengaruhi kapasitas menanggung beban. Pada dasawarsa 1980an dan purwa 1990an, banyak kuadran posterior rahang atas direstorasi dengan satu atau dua implant, dan pada beberap...

Pemakai implant gigi hati-hati makan ini

Implant gigi serupa gigi sejati tapi bukan gigi asli atau gigi sejati. Dengan implant gigi, pasien makan makanan seakan-akan tidak pakai gigi palsu. Kemampuan kunyah pasien kembali kira-kira 90% dari kemampuan semula ketika gigi sejati masih ada. Pemakai implant gigi dapat makan makanan apapun yang bisa dipotong pakai garpu biasa. Segera setelah prosedur Setelah prosedur implant gigi selesai, Dr...

Zirconium

Struktur atom zircon Nomor atom (jumlah proton dalam nukleus): 40. Simbol atom (pada tabel periodik elemen): Zr. Berat atom (rerata massa atom): 91.22 Kepadatan: 3.77 ons per inchi kubik (6.52 gram per cm kubik) Fase pada suhu kamar: Solid Titik leleh: 3,362 grad Fahrenheit (1,850 grad Celsius) Titik didih: 7,952 F (4,400 C) Jumlah isotop natural (atom dari elemen yang sama dengan juml...

Table : Partially limiting design

  author (y) material used for fabrication of the template radiographic marker used imaging system used conversion process indication/ advantages Engelman et al9 auto polymerizing acrylic resin metal bearings panoramic radiography remove lingual surface, leaving only facial surface of the teeth in the proposed implant site inexpensive, easy, improved visibility, external irr...

Conclusion : Types of Implant Surgical Guides in D...

Conclusion Although the completely limiting design is considered a far superior design concept, most clinicians still adopt the partially limiting design due to its cost-effectiveness and credibility in the field. In addition, it has been observed that most clinicians use surgical guide templates that are based on cross-sectional imaging to facilitate accurate planning and guidance during the sur...

CAD / CAM-based Surgical Guide : Types of Implant ...

CAD/CAM-based Surgical Guide CAD/CAM technology uses data from computerized tomography scan (CT)33 to plan implant rehabilitation. The CT images are converted into data that are recognized by a CT imaging and planning software. This software then transfers this presurgical plan to the surgery site using stereolithographic drill guides.34 CAD/CAM-based surgical guides offer many advantages. For e...

Completely Limiting Design : Types of Implant Surg...

Completely Limiting Design Completely limiting design restricts all of the instruments used for the osteotomy in a buccolingual and mesiodistal plane. Moreover, the addition of drill stops limits the depth of the preparation, and thus, the positioning of the prosthetic table of the implant. As the surgical guides become more restrictive, less of the decision-making and subsequent surgical executi...

Partially Limiting Design : Types of Implant Surgi...

In such designs, the first drill used for the osteotomy is directed using the surgical guide, and the remainder of the osteotomy and implant placement is then finished freehand by the surgeon.6 Techniques based on this design concept involve fabrication of a radiographic template, which is then converted into a surgical guide template following radiographic evaluation. Various authors have propos...

Nonlimiting Design : Types of Implant Surgical Gui...

Nonlimiting Design Nonlimiting designs only provide an indication to the surgeon as to where the proposed prosthesis is in relation to the selected implant site.6 This design indicates the ideal location of the implants without any emphasis on the angulation of the drill, thus allowing too much flexibility in the final positioning of the implant. Blustein et al7  and Engelman et al8 described...

Types of Implant Surgical Guides in Dentistry: A R...

Various techniques have been proposed for the fabrication of surgical guide templates in implant dentistry. The objective of this paper is to review the associated literature and recent advancements in this field, based on design concept. An electronic and hand search of the literature revealed 3 categories, namely, nonlimiting, partially limiting, and completely limiting design. Most clinicians s...

Simpulan: Implant gigi PEEK

Simpulan Laporan pustaka tentang implant gigi yang dibuat dari PEEK menunjukkan bahwa PEEK pada dasarnya dioseointegrasikan sebagai bahan biokompatibel in vivo. Penelitian lebih lanjut diperlukan untuk menemukan cara guna meningkatkan perilaku biomekanis untuk mencapai sebaran stress yang lebih homogen ke tulang sekitar yang belum pernah dapat dibuktikan dengan percobaan. Penelitian jangka panjan...

Tabel 4. Perbedaan rerata kedalaman penyisipan imp...

Tabel 4. Perbedaan rerata kedalaman penyisipan implant antara implant terbenam dan implant non-terbenam dari  Tabel 3    Implant non-terbenam, rerata kedalaman penyisipan implant dari Tabel 3, mm Implant terbenam, rerata kedalaman penyisipan dari Tabel 3, mm Perbedaan rerata kedalaman penyisipan implant, mm* Zirkonia -2.15 -2.62 +0.47 Zirkonia berlapis -2.56 -2.25 ...

Tabel 3. Rerata nilai BL terkait implant dan BL te...

Tabel 3. Rerata nilai level tulang terkait implant dan terkait tulang (Koch et al) dan rerata kedalaman penyisipan implant   Rerata BL terkait tulang, mm Rerata BL terkait implant, mm Rerata kedalaman penyisipan implant, mm Non-tenggelam       Zirkonia -0.53 -1.62 -2.15 Zirkonia berlapis -0.59 -1.97 -2.56 Titanium -0.37 -1.65 -2.02 ...

Wedharan: Implant gigi PEEK

Wedharan Menunjuk ke analisis element terbatas 3 dimensi pada implant titanium dan implant CFR-PEEK (Tabel 1), para pengarang penelitian ini menyimpulkan bahwa karena konsentrasi stresnya yang lebih tinggi, implant CFR-PEEK tidak dapat direkomendasikan.11 Tingkat deformasi ini barangkali bisa dikecilkan dengan pengerasan bagian dalam implant, contohnya, dengan sekrup koneksi penyangga yang meman...

Tabel 2. Gambaran lumrah 2 penelitian binatang in ...

Tabel 2. Gambaran lumrah 2 penelitian binatang in vivo Pengarang Cook dan Rust-Dawicki Tahun terbit 1995 Jumlah sato 4 (anjing mongrel) Jumlah implant 40 Jumlah implant / sato 10 Tempat implantasi Femur Masa penyembuhan 4 minggu (n = 2); 8 minggu (n = 2) Rancangan implant Silindris Metode penyembuhan Terbenam/ tanpa beban Bahan implant ...

Tabel 1: Gambaran lumrah dari studi elemen hingga ...

Pengarang Sarot et al Tahun terbit 2009 Situs implantasi Model virtual 3 dimensi rahang bawah berdasarkan CT scan pilihan dengan total 212 irisan transversal dengan panjang 0.25 mm, yang terdiri dari tulang medullar yang dicakup dengan lapisan tulang kortikal 1.0 mm, dirancang dengan perangkat lunak Ansys DesignModeler v11 (ANSYS Inc, Canonsburg, PA) Per...

Weton: Implant gigi PEEK

Weton Pencarian metuken 5 artikel. Tiga di antaranya disertakan dalam tinjauan.11, 34, 35 Dua artikel dikecualikan karena tidak melaporkan tentang implant gigi PEEK.36, 37 Dari artikel yang disertakan, 2 artikel melaporkan penelitian pada sato34, 35 dan 1 artikel melaporkan tentang penelitian elemen terbatas in vitro.11 Tujuan dari penelitian elemen terbatas 3 dimensi ini adalah untuk membandin...

Bahan & metode: Implant gigi PEEK

Bahan dan metode Pencarian literatur Artikel-artikel untuk tinjauan sekarang ini ditemukan pakai mesin pencari PubMed dan pencarian untuk referensi dikutip dalam artikel-artikel ini. Semua artikel yang dipublikasikan sampai Desember 2010 telah ditinjau. Kata sebutan untuk pencarian berikut ini dipakai secara bersama-sama: "dental implant PEEK" (implant gigi PEEK).   Kriteria ikutserta Hanya ...

Pendahuluan: Implant gigi PEEK

Pendahuluan Implant gigi meningkatkan mutu hidup bagi banyak pasien penderita gigi copot.1 Bahan pilihan untuk implant endosseous oral adalah titanium murni. Bahan ini diperkenalkan pada purna dasawarsa 1960-an oleh Branemark.2 Meskipun implant yang didasarkan pada titanium dan paduan titanium, seperti Ti -6Al-7Nb dan Ti- 6Al-4V,3,4 punya dasar bukti, terbukti bahwa penggunaannya bisa berkorelasi...

Abstrak: Implant gigi PEEK

Andreas Schwitalla, DDS ; Wolf-Dieter Müller, PhD J Oral Implantol (2013) 39 (6): 743–749. https://doi.org/10.1563/AAID-JOI-D-11-00002   Abstrak Pemasangan implant gigi yang mengandung titanium dapat dikaitkan dengan berbagai komplikasi (contohnya, hipersensitif terhadap titanium). Artikel ini bertujuan mengevaluasi apakah ada penelitian yang melaporkan PEEK sebagai bahan alternatif untuk...

Conclusion: PEEK Dental Implants

Conclusion Literature reporting on dental implants made from PEEK demonstrate that PEEK is basically osseointegrated as biocompatible material in vivo. Further investigations are necessary to find ways to improve the biomechanical behavior to achieve a more homogenous stress distribution to the surrounding bone, which has not yet been experimentally proven. Long-term investigation...

Table 4. Differences in the mean insertion depths

Table 4. Differences in the mean insertion depths between submerged and nonsubmerged implants from Table 3    Nonsubmerged implants, mean insertion depths from Table 3, mm Submerged implants, mean insertion depths from Table 3, mm Differences in the Mean Insertion Depths, mm* Zirconia -2.15 -2.62 +0.47 Coated zirconia -2.56 -2.25 -0.31 Titanium ...

Table 3. Mean values of bone-related and implant-r...

Table 3. Mean values of bone-related and implant-related bone level (BL) (Koch et al) and the mean insertion depths   Mean bone-related BL, mm Mean implant-related BL, mm Mean insertion depth, mm Nonsubmerged       Zirconia -0.53 -1.62 -2.15 Coated zirconia -0.59 -1.97 -2.56 Titanium -0.37 -1.65 -2.02 PEEK -1.3 -0.44 -1.74 Submerged ...

Discussion: PEEK Dental Implants

Discussion Referring to a 3-dimensional finite element analysis of a CFR-PEEK and a titanium implant (Table 1), the authors concluded that due to its higher stress concentrations, the CFR-PEEK implant could not be recommended.11 This deformation rate could probably be diminished by an inner stiffening of the implant, for example, by an abutment connection bolt which extends to the apical region ...

Table 2. Overview of 2 in vivo animal investigatio...

Table 2. Overview of 2 in vivo animal investigations Author Cook and Rust-Dawicki Year of publication 1995 Number of animals 4 (mongrel dogs) Number of implants 40 Number of implants/ animal 10 Implantation site Femur Healing period 4 weeks (n = 2); 8 weeks (n = 2) Implant design Cylindrical Healing method Submerged/ unloaded Implant mat...

Table 1: Overview of an in vitro 3-dimensional fin...

Author Sarot et al Year of publication 2009 Implantation site Virtual 3-dimensional model of a lower jawa of region 35, based on a randomly chosen computerized tomography scan with a total of 212 transversal slices wit 0.25 mm in length, consisting of medullar bone covered by a 1.0-mm thick layer of cortical bone, designed with the software Ansys DesignModeler v11 (ANSYS Inc...

Result: PEEK Dental Implants

Results The search yielded 5 articles, of which 3 were included in the review.11, 34, 35 Two articles were excluded, because they did not report on dental implants of PEEK.36, 37 Of the included articles, 2 reported on animal investigations34, 35 and 1 on an in vitro finite element study.11 The aim of the 3-dimensional finite element study was to compare the stress distribution to the peri-impl...

Material & methods: PEEK Dental Implants

Materials and Methods Literature search The articles for the current review were found using the PubMed search engine and searching for references cited within these articles. All articles published until December 2010 were reviewed. The following search terms were used together: “dental implant PEEK.” Inclusion criteria Only articles about dental implants from PEEK or modified PEEK publis...

Introduction: PEEK Dental Implants

Introduction Dental implants increase the quality of life for many patients with tooth loss.1 The material of choice for oral endosseous implants is pure titanium, introduced at the end of the 1960s by Branemark.2 Although implants based on titanium and titanium alloys, such as Ti-6Al-7Nb and Ti- 6Al-4V,3, 4 are well evidence-based, it was demonstrated that their use can be correl...

Abstract: PEEK Dental Implants

Andreas Schwitalla, DDS ; Wolf-Dieter Müller, PhD J Oral Implantol (2013) 39 (6): 743–749. https://doi.org/10.1563/AAID-JOI-D-11-00002   Abstract The insertion of dental implants containing titanium can be associated with various complications (eg, hypersensitivity to titanium). The aim of this article is to evaluate whether there are existing studies reporting on PEEK as an alternative m...

Tabel 2: zirkonia berpermukaan halus

Tabel 2 Evaluasi Uji Torsi Pelepasan (RTQ) berdasarkan karakteristik permukaan implant investigator karakteristik permukaan implant weton RTQ Gahlert, 2007 Zirkonia berpermukaan halus 25.9 N/cm Gahlert, 2007 Zirkonia sandblast 40.5 N/cm Gahlert, 2007 Titanium SLA 105.2 N/cm Sennerby, 2005 Zirkonia berpermukaan halus Significantly lower RTQ values ...

Table 2: Zirconia dental implants

Table 2 Removal torque testing (RTQ) evaluation according to surface characteristic of implants investigator surface characteristics of implants results of RTQ Gahlert, 2007 Machined zirkonia 25.9 N/cm Gahlert, 2007 Sandblasted zirconie 40.5 N/cm Gahlert, 2007 SLA titanium 105.2 N/cm Sennerby, 2005 Machined zirconia Significantly lower RTQ values ...

Tabel 1 : implant gigi zirkonia

Tabel 1 Penelitian-penelitian in vitro yang memeriksa kontak tulang-implant berbagai implant yang berbeda investigator macam implant period tindak lanjut kontak tulang implant Akagawa, 1993 Zirkonia non-beban 3 bulan 81.9 Akagawa, 1993 Zirkonia dengan beban 3 bulan 69.8 Dubruille, 1999 Titanium 10 bulan 54 Dubruille, 1999 Alumina 10 bul...

Table 1 : zirconia dental implants

Table 1 In vitro studies examining bone-implant contact of different implants investigator type of implant follow-up period bone-implant contact Akagawa, 1993 Nonloaded zirconia 3 mo 81.9 Akagawa, 1993 Loaded zirconia 3 mo 69.8 Dubruille, 1999 Titanium 10 mo 54 Dubruille, 1999 Alumina 10 mo 68 Dubruille, 1999 Zirconia 10 mo 64.6 Scarano, ...

Simpulan: implant gigi zirkonia

5. Analisis tekanan Satu penelitian mengevaluasi analisis tekanan. Kohal et al mengamati pola sebaran tekanan dari implant zirkonia (ReImplant). Weton pengamatan menunjukkan bahwa sebaran tekanan itu rendah, tersebar dengan baik, dan sebaran tekanannya serupa bila dibandingkan dengan implant titanium. Pola ini bisa dicirikan sebagai pola yang menguntungkan atau tidak merusak. Nilai tekanan di...

Conclusion: zirconia dental implants

5. Stress analysis One study evaluated stress analysis. Kohal et al observed the stress distribution patterns of zirconia implants (ReImplant), which were found to have low, well distributed, and similar stress distribution compared with titanium implants. These patterns could be characterized as favorable or nondestructive. Stress values were found to be similar for both models for all regi...

Kekuatan: implant gigi zirkonia

4. Kekuatan Minamizato et al menyelidiki kekuatan kompresif implant gigi zirkonia tipe bilah dengan lorong yang dibor pakai proses laser. Mereka menemukan bahwa spesimen dengan lorong menunjukkan kekuatan kompresif yang rendah (237 kg/mm2) dibandingkan spesimen tanpa lorong (371.5 kg/mm2). Mereka menyimpulkan bahwa bilah zirkonia punya kekuatan yang cukup dalam oklusi. Kohal...

Strength: Zirconia dental implants

4. Strength Minamizato et al investigated the compressive strength of the blade type of zirconia dental implants with tunnels drilled by laser process, and found that specimens with tunnels showed lower compressive strength (237 kg/mm2) than specimens without tunnels (371.5 kg/mm2). They concluded that zirconia blades had adequate strength in occlusion. Kohal et al evaluated the frac...

RTQ (uji torsi pelepasan): implant gigi zirkonia

3. RTQ (test torsi pelepasan) Sennerby et al., mengamati respons jaringan tulang terhadap implant zirkonia berpermukaan halus dan implant yang berpermukaan termodifikasi. Untuk mendapat permukaan berpori, implant zirkonia dilapisi dengan 2 macam bubur yang berbeda, masing-masing mengandung bubuk zirkonia dan bekas pori, yang memberikan struktur permukaan yang berbeda. Implant zirkonia tanpa lapis...

RTQ (removal torque testing): zirconia dental impl...

3. RTQ (removal torque testing) Sennerby et al observed bone tissue responses to machined and surface-modified zirconia implants. To achieve a porous surface, the zirconia implants were coated with 2 different slurries containing zirconia powder and a pore-former, which gave different surface structures. Noncoated zirconia implants were used as controls. In addition, titanium i...

Analisis permukaan : implant gigi zirkonia

2. Surface analyses Analisis permukaan dilakukan dalam 4 penelitian. Dalam penelitian pertama, Yang et al meneliti zirkonia dengan 4% CeO2 dan zirkonia dengan 3% lapisan Y2O3, yang diendapkan pada implant titanium dan implant CoCrMo menggunakan teknik semprotan plasma. Properti adesif, morfologis, dan struktur pada lapisan yang disemprot plasma dievaluasi. Rata-rata kekasaran permukaan zirkonia d...

Surface analyses : zirconia dental implants

2. Surface analyses Surface analyses were performed in 4 studies. In the first study, Yang et al investigated zirconia with 4% CeO2 and zirconia with 3% Y2O3 coatings, which were deposited on titanium and CoCrMo implants using the plasma spraying technique. Adhesive, morphologic, and structural properties of the plasma-sprayed coatings were evaluated. The average surface roug...

Oseointegrasi, analisis histologi, dan BIC : impla...

1. Oseointegrasi, analisis histologis, dan BIC Eighteen articles discussed osseous healing, histologic analyses, and BIC of zirconia dental implants. Seven of these articles evaluated zirconia as a coating material, evaluated zirconia dental implants. Delapan belas artikel medhar penyembuhan osseus, analisis histologis, dan BIC dari implant gigi zirkonia. Tujuh di antara artikel ini mengevaluasi...

Osseointegration, histologic analyses, and BIC : z...

1. Osseointegration, histologic analyses, and BIC Eighteen articles discussed osseous healing, histologic analyses, and BIC of zirconia dental implants. Seven of these articles evaluated zirconia as a coating material, evaluated zirconia dental implants. Zirconia as a Coating Material Cranin et al investigated the osseointegration of vitallium implants with the addit...

Weton: Implant gigi zirkonia

Weton Pencarian PubMed metuken 108 artikel. Jumlah total karangan yang memenuhi kriteria untuk tinjauan ini ada 37. Dari jumlah ini, 30 di antaranya adalah penelitian laboratorium, 3 penelitian klinis, 2 laporan kasus, dan 2 artikel ulasan. Sebagian besar penelitian dilakukan secara in vitro (1,2,11,18,20-45). Oseointegrasi dan BIC diselidiki dalam 18 artikel (2,18,20-35), analisis permukaan dal...

Results: Zirconia dental implants

Results The PubMed search resulted in 108 articles. The total number of papers that met the inclusion criteria for this review was 37. Of these, 30 were laboratory studies, 3 were clinical studies, 2 were case reports, and 2 were review articles. Most of the studies were conducted in vitro (1,2,11,18,20-45). Osseointegration and bone-implant contact (BIC) were investigated in 18 articles...

Bahan & metode : implant gigi zirkonia

Tinjauan ini mulai dengan pencarian di PubMed dari 1975 sampai 2009. Pencarian dilakukan pakai kata kunci: zirconia, zirconium dioxide, dental, dan implant. Jika bisa, seluruh teks artikel diambil. Jika tidak bisa mengambil seluruh teks, maka dikumpulkan abstrak elektronik yang tersedia. Jadi, kriteria inklusi untuk artikel adalah sebagai berikut:  Artikel berkaitan dengan implant gigi zirkoni...

Materials & methods : Zirconia Dental Implants

This review started with a PubMed search from 1975 to 2009. The search was conducted using the following key words: zirconia or zirconium dioxide, dental, and implant. The full text of articles was obtained where possible. If it was not possible to obtain a full text, the electronically available abstracts were collected. Thus, the inclusion criteria for articles were as follows: Articles ...

Pendahuluan : Implant gigi Zirconia

Rehabilitasi pasien ompong lengkap dan pasien ompong sebagian pakai implant gigi adalah modalitas perawatan yang diterima secara widyan dan didokumentasikan dengan baik. Kala ini, titanium dan paduan titanium adalah bahan yang paling sering digunakan dalam pembuatan implant dan telah menjadi standar emas untuk penggantian gigi dalam implantologi gigi. Bahan-bahan ini telah mencapai penggunaan arus...

Introduction : Zirconia Dental Implants

The rehabilitation of completely and partially edentulous patients with dental implants is a scientifically accepted and well documented treatment modality. Currently, titanium and titanium alloys are the materials most often used in implant manufacturing and have become a gold standard for tooth replacement in dental implantology. These materials have attained mainstream use because of their ex...

Implant gigi zirconia: Tinjauan literatur

Abstrak Titanium dan paduan titanium banyak digunakan untuk pembuatan implant gigi. Karena potensi imunologi dan pangintenan implant titanium mengganggu estetika, teknologi implant baru sedang dikembangkan. Namun, teknologi baru ini harus mempertahankan karakteristik yang memberi implant titanium tingkat kesuksesan yang tinggi. Implant zirkonia dimasukkan ke dalam implantologi gigi sebagai altern...

Zirconia Dental Implants: A Literature Review

Abstract Titanium and titanium alloys are widely used for fabrication of dental implants. Because of potential immunologic and possible esthetic compromises with titanium implants, novel implant technologies are being developed. However, these novel technologies must maintain the characteristics that provide titanium implants with their high success rates. Zirconia implants were introduced ...

Wedharan: Implant pendek dalam rehabilitasi rahang...

Wedharan Laporan ini menunjukkan bahwa implan pendek dapat mencapai weton klinis dan radiografis yang optimal pada tindak lanjut 1 tahun ketika digunakan untuk restorasi tunggal atau ketika terhubung dengan implant lain guna mengganti lebih dari satu gigi. Tidak ada perbedaan weton antara restorasi rahang bawah dan restorasi rahang atas meskipun volume tulang dengan kuantitas yang lebih tinggi di...

Discussion: Short implants in maxillary and mandib...

The present report showed that short implants may achieve optimal clinical and radiographic outcomes at the 1-year follow-up when used for single restoration or when connected with other implants in substituting for more than one tooth. There was no difference in outcomes between mandibular and maxillary restorations even though a higher quantity of bone volume was required in mandibular restora...

Weton: Implant pendek dalam rehabilitasi rahang at...

Weton Sebaran panjang dan diameter implant ditampilkan dalam Tabel 1. Tabel 2 merinkes posisi implant dan ciri prostetik. Rerata tinggi tulang sisa adalah 6.21 ± 1.05 mm di rahang atas dan 10.73 ± 1.63 mm di rahang bawah. Perbedaan di antara 2 rahang itu signifikan (P < 0.05). Tidak ada komplikasi bedah atau pasca bedah yang dilaporkan. Tabel 2. Posisi implant dan ciri prostetik; implant ante...

Results: Short implants in maxillary and mandibula...

Implant length and diameter distribution are shown in Table 1. Table 2 summarizes implant positions and prosthetic characteristics. Mean residual bone height was 6.21 ± 1.05 mm in the upper jaw and 10.73 ± 1.63 mm in the mandible, and it was significantly different between the 2 jaws (P < .05). No surgical or postsurgical complications were reported. Table 2. Implant positions and prostheti...

Analisis data: Implant pendek dalam rehabilitas ra...

Dalam laporan sementara ini, data 1 tahun mengenai resorpsi tulang dinilai. Tingkat kelangsungan hidup implant dan tingkat sukses dievaluasi dengan membandingkan implant rahang atas dan rahang bawah, implant belat dan implant tunggal, dan implant dengan panjang yang berbeda. Tes Student t digunakan untuk membandingkan resorpsi tulang antara implant rahang bawah dan implant rahang atas serta antara...

Data analysis: Short implants in maxillary and man...

In this ad interim report, 1-year data regarding bone resorption were assessed. Implant survival and success rates were evaluated by comparing maxillary and mandibular implants, splinted and single implants, and implants of different lengths. A Student t test was used to compare bone resorption between mandibular and maxillary implants and splinted and single implants. Analysis of variance was u...

Evaluasi klinis dan radiologis: Implant pendek dal...

Evaluasi klinis dilakukan setiap 6 bulan sekali untuk 2 tahun pertama. Selanjutnya, evaluasi klinis dilakukan setahun sekali. Tingkat kelangsungan hidup implant dan tingkat sukses dievaluasi dan direkam. Komplikasi bedah, prostetik, dan klinis direkam. Kesuksesan prostetik dievaluasi sebagai berikut: prostesis berfungsi, tidak bergerak, dan tidak nyeri, bahkan bila satu implant atau lebih akan lep...

Clinical and radiological evaluation: Short implan...

Clinical evaluation was performed every 6 months for the first 2 years then yearly. Survival and success rates were evaluated and recorded, following the definitions and parameters described elsewhere. Any surgical, prosthetic, or clinical complication was recorded. Prosthetic success was evaluated as follows: prosthesis in function, without mobility and pain, even if in the face of the loss of o...

Prosedur bedah dan prostetik: Implant pendek dalam...

Profilaksis antibiotik dengan amoksisilin 2 g diberikan kepada semua pasien 1 jam sebelum operasi pada semua pasien. Semua implant ditempatkan di tempat yang disembuhkan dan soket tulang disiapkan menggunakan teknik atraumatik standar dengan urutan pengeboran bersesuaian dengan peningkatan diameter pada panjang yang telah ditentukan. Situs implant selalu disiapkan kurang dari seharusnya, dengan ...

Surgical and prosthetic procedure: Short Implants ...

Antibiotic prophylaxis with amoxicillin 2 g was administered to all patients 1 hour before surgery in all patients. All implants were placed in healed sites and the bone socket was prepared using a standard atraumatic technique with a sequence of drills of increasing diameter at the decided length. The implant site was always underprepared, taking in consideration the bone density. All implants ...

Bahan & metode: Implant pendek dalam rehabilitasi ...

Penelitian kohort tunggal prospektif ini dirancang dan dilakukan mengikuti prinsip-prinsip  the World Medical Association Helsinki Declaration 1975 untuk riset biomedis yang melibatkan subyek manusia, seperti yang direvisi pada tahun 2000. Persetujuan etika untuk penelitian ini telah diperoleh dari Parepatan Peninjau IRCCS Istituto Ortopedico Galeazzi. Semua pasien diberi informasi tentang tuj...

Materials & methods: Short implants in maxillary a...

This prospective single-cohort study was designed and conducted following the principles of the World Medical Association Helsinki Declaration of 1975 for biomedical research involving human subjects, as revised in 2000. Ethical approval for the study was obtained by the review board of the IRCCS Istituto Ortopedico Galeazzi. All patients were informed about the study aims and design and gave w...

Pendahuluan: Implant pendek dalam rehabilitas raha...

Pendahuluan Rehabilitasi implant di derah posterior rahang atas dan rahang bawah bisa jadi rehabilitasi yang rumit dalam kasus susut volume tulang dampak resorpsi tulang setelah cabut gigi atau kondisi anatomi tertentu. Faktanya, susut tinggi tulang dapat mencegah pemasangan implant panjang (> 10 mm) karena risiko melibatkan struktur anatomi, seperti sinus maksilaris atau...

Introduction: Short implants in maxillary and mand...

Introduction Implant rehabilitation in the posterior regions of the maxilla and mandible can be complicated in cases of reduced bone volume due to bone resorption after teeth extraction or to particular anatomic conditions. In fact, reduced bone height can prevent long implants (>10 mm long) from being placed because of the risk of involving anatomic structures, such as ...

Abstrak: Implan pendek dalam rehabilitasi rahang a...

Short Implants in Maxillary and Mandibular Rehabilitations: Interim Results (6 to 42 Months) of a Prospective Study  J Oral Implantol (2015) 41 (1): 50–55. https://doi.org/10.1563/AAID-JOI-D-12-00206   Penelitian kohort tunggal ini bertujuan untuk mengevaluasi kelangsungan hidup klinis dan keberhasilan rehabilitasi parsial yang didukung oleh implant yang p...

Abstract: Short implants in maxillary and mandibul...

Short Implants in Maxillary and Mandibular Rehabilitations: Interim Results (6 to 42 Months) of a Prospective Study  J Oral Implantol (2015) 41 (1): 50–55. https://doi.org/10.1563/AAID-JOI-D-12-00206 The aim of this single-cohort study was to evaluate clinical survival and success of partial rehabilitation supported by reduced-length implants in maxilla and ...

Berapa harga implant gigi 2020 lengkap dari mula s...

Harga implant gigi dan harga perawatan implant gigi untuk tahun 2020 relatif serupa seperti tahun 2018 & 2019. Penanaman dan perawatan implant gigi lengkap dari mula hingga tuntas masih berkisar antara Rp 12 juta sampai Rp 21 juta, bergantung pada beberapa pertimbangan sebagai berikut: Merek pasak implant, abutment (penyangga), dan crown (mahkota) yang Anda pilih. Biasanya, har...

Simpulan: tatalaksana sekrup penyangga implant yan...

Simpulan Sekrup penyangga (abutment) yang pecah pada mahkota gigi yang didukung oleh implant endosseous merupakan komplikasi yang tidak menyenangkan. Pecahan yang tertahan dalam piranti dapat diambil dengan bor festooned berlubang # 557 berkecepatan lambat yang disetel dengan torsi terbalik. Begitu fragmen dilonggarkan dan maju pada arah koronal, bor #33 1/3 yang diputar searah jarum jam di...

Wedharan: tatalaksana sekrup penyangga implant yan...

Wedharan Komplikasi lumrah dari prostetik implant adalah komplikasi dengan komponennya. Sekrup penyangga menghubungkan bagian abutment ke piranti dan dapat patah karena beban fungsional oklusal. Ketika menyiapkan perawatan pasien penderita fraktur sekrup penyangga, dokter harus mengambil radiografi untuk memastikan kualitas dukungan tulang pendukung implant. Lubang sekrup piranti harus disiram...

Pendahuluan: tatalaksana sekrup penyangga implant ...

Pendahuluan Implant gigi telah menjadi modalitas pemaju kehidupan bagi pasien ompong sebagian dan ompong total. Implant bisa sukses mendukung mahkota tunggal yang disemen atau ditahan dengan sekrup. Namun, modalitas ini bukan tanpa komplikasi: Sekrup penyangga bisa patah ketika prostesis berada di bawah pembebanan siklik fungsional. Sekrup penyangga bisa saja kelebihan beban dan patah, meninggalk...

Conclusion: management of a fractured implant abut...

Conclusions A fractured abutment screw of a crown supported by an endosseous implant is an unhappy complication. The fragment retained in the fixture can be retrieved with a festooned #557 latch slow-speed burr set in reverse torque. Once the fragment is loosened and advanced coronally, a clockwise-turning #33 1/3 burr is touched to the fragment side to completely remove it. Care is taken n...

Discussion: management of a fractured implant abut...

Discussion A common complication of implant prosthetics is with components. The abutment screw connects the abutment to the fixture and can fracture under occlusal functional load. In preparation for treatment of a patient presenting with an abutment screw fracture, a radiograph should be taken to ensure osseous support quality of the supporting implant. The fixture screw hole should be flush...

Introduction : management of a fractured implant a...

Introduction Dental implants have been a life-enhancing modality for partially and completely edentulous patients. Implants can successfully support a cemented or screw-retained single crown. However, this modality is not without complications: A fractured abutment screw may occur when the prosthesis is under functional cyclic loading. The abutment screw may be overloaded and fracture, leaving th...

Implant gigi apa selalu lebih baik daripada gigi p...

Selalu? Kalau disebut "selalu", tidak selalu karena pasien tidak selalu perlu implant gigi atau, jika pun pasien perlu, tidak selalu semua orang bisa menerima perawatan implant gigi. Ada kriteria perawatan implant gigi yang perlu dipenuhi untuk menerima implant gigi. Tidak selalu orang bisa memenuhi kriteria-kriteria tersebut. Kita ambil contoh pasien yang sebetulnya perlu perawatan implant gigi ...

Aneka prosedur implant gigi

1. Implant satu tahap (One-stage implant) Implant dipasang dengan menyembulkan bagian atasnya di permukaan gusi. Prosedur ini tidak perlu operasi kedua untuk menyembulkan implant gigi karena implant sudah terlihat di permukaan gusi. Implant dua tahap (Two-stage implant) Implant ditanam di dalam gusi kemudian bekas operasi ditutup sampai implant jadi. Setelah itu, operasi kedua dilakukan unt...

Perawatan implant gigi tuntas sehari, mungkinkah?

Ya, mungkin, asalkan tidak ada infeksi dalam mulut pasien dan kondisi jiwa-raga pasien benar-benar prima. Walaupun begitu, pasien perlu tahu bahwa implant gigi sehari terpasang tidak sama artinya dengan implant gigi sehari jadi. Apa bedanya? Implant gigi sehari terpasang berarti implant gigi terpasang di tempatnya dengan ditahan oleh benang jahit. Kemudian di atas daerah operasi itu dipasang cro...

Gigi implant - gigi palsu paling mirip gigi asli

Para pakar di bidang kedokteran gigi telah mengembangkan teknik modern gigi palsu mirip gigi sejati untuk mengganti gigi ompong. Teknik tersebut melibatkan penggunakan satu set gigi implant lengkap. Gigi implant disebut juga gigi palsu implant atau gigi palsu tanam karena macem gigi palsu ini bukan hanya ditumpangkan pada gusi, tapi juga ditanam ke dalam gusi. Penanaman gigi palsu tanam ke dalam ...

Implant gigi terutama untuk mengatasi ompong

Perawatan implant gigi sudah sering diterapkan sebagai prosedur prostodentik yang paling penting. Prosedur tersebut punya prediktabilitas jangka panjang untuk merestorasi fungsi mulut, mempertahankan oklusi, dan memperbaiki kualitas hidup pasien. Dari segi klinis, implant gigi terutama diterapkan untuk memperbaiki ompong yang memanjang pada arah distal di rahang bawah. Namun, penempatan implant g...

Mengganti geraham bawah dengan implant gigi

Masazumi Yoshitani, Yoshiyuki Takayama, dan Atsuro Yokoyama meneliti tentang nilai penting mengganti gigi geraham rahang bawah yang sudah hilang dengan implant gigi. Penelitian yang dilakukan adalah studi teoritis dengan analisis elemen terbatas non-linier. Hasil penelitian mereka diterbitkan dalam International Journal of Implant Dentistry tanggal 27 Februari 2018. Penelitian tersebut dilatarbel...

Dampak positif implant gigi apa saja?

Implant gigi punya dampak positif dalam berbagai bidang kehidupan pasien. Bidang kesarasan Bidang komunikasi Bidang estetika Bidang psikologis Bidang kehidupan sosial Bidang rumah tangga Di bidang kesarasan, implant gigi membuat pasien pemakai implant gigi mengunyah makanan jadi lebih baik. Hal ini berpengaruh pada pencernaan pasien. Makanan yang dikunyah halus lebih mudah dilumat...

Berapa harga termurah pasang implant gigi?

KIsaran Rp 8 juta.  Harga tersebut belum termasuk abutment/ connector, crown, pemasangan abutment dan crown, perawatan tambahan bila terjadi komplikasi, bone graft jika diperlukan, operasi reentry, dan layanan-layanan lain. Harga kisaran Rp 8 juta meliputi pasak implant gigi (akar gigi tiruan) dan pemasangan implant gigi saja. Tapi, apa gunanya pasien pasang implant gigi saja jika implant terseb...

Efek rokok pada implant gigi

Tulisan berikut ini diambil dari penelitian yang dilakukan oleh Sun, et al tentang pengaruh merokok berat pada implant gigi yang dipasang pada rahang bawah posterior pasien pria. Penelitian diterbitkan dalam Journal of Oral Implantology edisi Desember 2016, Vol. 42, No. 6, pp. 477-483. Penelitian Sun, et al bertujuan untuk mengevaluasi stabilitas implant gigi dan respon jaringan peri-implant pa...

Betulkah gigi implant membuat bau mulut?

Tidak. Bau mulut bukan berasal dari gigi implant, tapi dari pembersihan daerah sekitar implant gigi kurang baik. Bau mulut berasal dari sisa-sisa makanan yang menyelip dan membusuk. Proses pembusukan dilakukan oleh bakteri dalam mulut. Selama sisa makanan yang membusuk itu belum dibersihkan, mulut terus bau. Cara untuk mengatasi bau mulut di sekitar gigi implant adalah menyikat gigi, lidah, dan ...

Berapa harga gigi implant semua?

Gigi implant lengkap untuk satu rahang hanya memerlukan antara 4 sampai 8 implant gigi. Jika Anda ingin memasang gigi implant lengkap untuk rahang atas bawah, maka perlu implant gigi antara 8 sampai 16 buah. Mengganti 32 gigi ompong tidak perlu memasang 32 implant gigi, cukup antara 8 sampai 16 buah saja. Gambarannya seperti pada foto tersebut di atas. Perkiraan harga untuk gigi implant lengkap/ ...

Makanan yang tidak boleh dimakan oleh orang yang m...

Semua makanan favorit boleh dimakan, kecuali makanan yang punya ciri berikut ini: Minuman & makanan yang terlalu panas di atas 47° C. Implan terbuat dari logam titanium yang punya sifat menghantarkan panas. Panas yang terlalu tinggi akan dihantarkan oleh implant ke tulang. Sel-sel tulang penopang implant cuma tahan hingga suhu 47° C. Di atas suhu ini, sel tulang mati. Jika sel mati, mak...

Klinik dental implant Jakarta ada di mana?

Klinik dental implant Jakarta berada di Jakarta Barat. Tepatnya di Jl. Pos Pengumben No. 40c & Jl. Palmerah Barat No. 108. Klinik Pos Pengumben Klinik Palmerah   Layanan umum: (+62)212253 9385 (Pos Pengumben) (+62)2153654792 (Palmerah) (+62)2153654792 (Palmerah) Layanan implant gigi: Telpon: +6281291668166, PIN BB: 2B953BCF, 232BAFD6, Email: klinikdoctordentist@gmail.co...

Bagaimana jika dokter membor terlalu dalam saat me...

Kami mengerti kecemasan Anda.  Sebetulnya, pemboran yang terlalu dalam tidak selalu merugikan, tergantung dari berapa milimeter yang disebut "terlalu dalam" itu. Kalau kelebihan 1 mm, tidak berpengaruh signifikan. Malah, dokter bisa menggunakan kelebihan 1 mm ini untuk mengatur kedalaman implant gigi. Terlalu dalam 2 mm tidak berpengaruh signikan jika tulang Anda tebal. Nantinya tulang akan meng...

Apa desain implant memengaruhi stabilitas primer i...

Tujuan penelitian ini adalah untuk menilai stabilitas implant gigi dalam hubungannya dengan desain implant memakai analisis frekuensi resonansi. Desain implant yang diteliti adalah kerucut vs semi kerucut dan pitch lebar vs pitch sempit. Duapuluh pasien dengan daerah premolar ompong bilateral di rahang atas dipilih untuk penelitian ini. Implant kerucut dengan pitch lebar (kelompok 1) dipasang dal...

Berapa harga implant gigi 2018?

Harga implant gigi dan harga perawatan implant gigi untuk tahun 2018 tidak banyak berubah dibandingkn harga serupa pada tahun 2016 & 2017. Penanaman dan perawatan implant gigi masih berkisar antara Rp 12 juta sampai Rp 21 juta, bergantung pada aneka faktor, antara lain: Merek implant, abutment, dan crown yang Anda pilih. Produk dengan merek-merek top seperti Strauman atau Biocare berharga leb...

Implant gigi expandable & pendek untuk gusi yang s...

Implant endosseous telah dimapankan selama beberapa dasawarsa. Evaluasi hasil-hasil perawatan implant di bawah aspek-aspek biomekanis, fisiologis, psikologis, sosial, dan ekonomis telah didokumentasikan dengan baik.1 Lebih dari itu, hasil-hasil berbasis pasien mengungkapkan keuntungan kualitas hidup terkait kesarasan mulut dan keuntungan itu mudah diprediksi.2 Proses perawatan implant gigi pada p...

Implant gigi expandable pendek

Implant gigi yang berukuran pendek sering punya kelemahan dalam prakara stabilitas primer yang lebih rendah dibandingkan implant panjang. Tantangan ini dipecahkan dengan implant pendek yang bisa mengembang seperti payung (lihat video). Penelitian yang dilakukan oleh Waldemar Reich et al. dari Universitas Martin Luther, Jerman, menunjukkan bahwa implant pendek inovasi baru ini meningkatkan stabilit...

Apakah tubuh manusia bisa menerima benda asing imp...

Bergantung pada bahan apa yang dipakai untuk membuat implant gigi itu. Tubuh manusia dapat menerima implant gigi yang dibuat dari titanium. Malah bukan hanya bisa menerima. Lebih dari itu, tulang tubuh manusia bisa menempel dan menyatu dengan titanium. Proses penyatuan ini dikenal dengan nama teknis "oseointegrasi", dari kata "oseo" yang berarti tulang dan kata "integrasi" yang berarti berpadu. Na...

Kenapa orang pasang implant gigi?

Motif orang pakai gigi palsu terutama agar bisa makan dengan lebih enak dan agar tidak kempot/ peot sehingga wajah jadi terlihat lebih muda bila dibandingkan bila ia kempot/ peot.  Motif orang pasang gigi implant sebetulnya tidak jauh berbeda dari orang-orang yang pasang gigi palsu konvensional, yaitu agar bisa makan lebih enak dan agar tidak kempot/ peot. Bedanya, makan pakai gigi implant lebih...

Apa crown gigi implant seawet implant gigi?

Barangkali tidak karena crown terus dipakai untuk mengunyah makanan setiap hari dan bergesekan dengan gigi oposisi di hadapannya, sehingga peluang untuk aus karena gesekan jadi lebih besar dibandingkan implant yang tidak terkena gesekan langsung. Gigi implant (implanted tooth) terdiri dari bagian crown, abutment atau connector,dan bagian pasak implan gigi (akar tiruan). Biasanya pasak implant gig...

2 gigi geraham saya sudah dicabut. Apa bisa pasang...

Bisa dong. Jangankan hanya pasang 2 sekaligus. Pasang  sekaligus 5, 8, atau seluruh gigi juga bisa sekaligus. Bukan cuma sekali kami menangani kasus seperti yang Anda alami. Pengalaman kami untuk kasus yang Anda sampaikan cukup banyak. Satu di antaranya, lihat pada foto di atas dan silakan diklik. Foto tersebut diambil dari seorang pasien kami yang juga 2 gerahamnya sudah copot. Implant gigi la...

Apa gigi implant dipasang pakai lem perekat gigi p...

Biasanya, apa yang dimaksud oleh pemasar, pengiklan, dan penjual dengan kata "gigi palsu permanen" itu gigi palsu tanam atau gigi implant. Walaupun penggunaan kata "permanen" tidak mutlak akurat tapi maksudnya begitu di luar konteks klinik atau rumah sakit. Dalam konteks professional implant gigi, kata yang lebih tepat untuk dipakai adalah gigi implan, implan gigi, gigi palsu tanam, atau yang seje...

Implant gigi meningkatkan hubungan sex

Implant gigi meningkatkan hubungan sex pada pasien penderita ompong. Demikian ringkasan simpulan dari penelitian yang dilakukan oleh Guido Heydecke, Mark Thomason, James P Lund, dan Jocelyne S Feine. Weton penelitian diterbitkan dalam Journal of Dentistry pada tanggal 7 Januari 2005 dengan judul "The impact of conventional and implant supported protheses on social and sexual activities in edentulo...

Apa tanam implant gigi perlu bius?

Ya. Operasi tanam ini pakai prosedur operasi. Karena itu pasien dibius sesuai prosedur. Pembiusan diperlukan agar pasien merasa lebih nyaman selama proses operasi tanam implan gigi. Tipe bius apa yang pasien terima sebetulnya bergantung pada tingkat kenyamanan pasien itu sendiri, di samping juga preferensi dokter dan jumlah implant gigi yang akan dipasang. Dokter akan mengecek efek bius setelah p...

Apakah implant gigi sakit?

Tidak. Operasi implant gigi tidak sakit karena pasien dibius lokal atau total kala operasi tanam gigi dilakukan. Perawatan implant gigi juga tidak sakit. Setelah implan gigi jadi, kira-kira 4 bulan setelah operasi implan dilakukan, implan gigi yang telah terpasang itu juga tidak sakit. Kenapa operasi implan gigi tidak terasa sakit? Karena dokter gigi implant lebih dulu menyuntik pasien dengan ob...

Kenapa gigi implant bisa populer?

Teknologi implant gigi relative baru dibandingkan teknologi gigi palsu macem lain. Meskipun begitu, popularitas gigi implan melesat cepat sekali. Hal ini terutama terlihat jelas di negara-negara maju dengan tingkat kesejahteraan yang lebih tinggi. Berikut beberapa faktor yang melatarbelakangi kenapa gigi implan bisa populer. 1. Terlihat mirip dengan gigi asli Crown gigi implant sangat mirip deng...

Apa beda gigi implant dan gigi palsu?

Gampangnya, gigi implant adalah gigi palsu yang ditanam ke tulang rahang, sehingga disebut pula gigi tanam atau gigi palsu tanam. Gigi implant punya akar gigi yang tertanam dalam tulang rahang, sedangkan gigi palsu biasa tidak punya bagian akar tiruan dan hanya diletakkan "menumpang" pada gusi. Gigi implan itu macem gigi palsu yang ditanam. Kelebihan gigi implant dibandingkan gigi palsu biasa ada...

Implant gigi itu apa?

Implant gigi adalah akar gigi buatan yang ditanam ke dalam tulang rahang, mirip dengan akar gigi yang sejati tertanam ke dalam tulang rahang. Gigi palsu kemudian dipasang di atas akar gigi buatan tersebut. Gigi palsu dan implan itu disebut pula gigi palsu tanam karena gigi palsu macem ini ditanamkan ke dalam rahang, bukan hanya nempel atau ditumpangkan di atasnya saja. Sedangkan akar giginya saja...

Apa beda gigi implant dan gigi palsu permanen?

Bedanya adalah bidangnya. Gigi implant dan implan gigi menyiratkan aspek teknik kedokteran gigi dan dipakai oleh dokter gigi dalam konteks lembaga kedokteran gigi seperti rumah sakit, klinik gigi, dan asosiasi dokter. Kata ini dipakai di bidang kedokteran. Dokter menggunakan kata "implan gigi" kepada pasien. Gambar gigi palsu permanen antara lain seperti pada gambar di atas. Nama "gigi palsu per...

Bagaimana tingkat komplikasi perawatan implant gig...

BEDA-BEDA. Tingkat komplikasi perawatan implan gigi diperingaruhi oleh implant yang dipakai dan tipe prostetik yang digunakan.  A. Implant dengan crown tunggal. Fraktur pada crown: keramik metal: 95,4 persen1 keramik saja: 95,4 persen1 tingkat kumulatif fraktur keramik atau fraktur veneer: 4.5 percent1 Peri-implantitis: 9,7 persen1 sampai dengan 56 persen2 Fraktur implan:...

Implan gigi depan atas

Implant gigi layak digunakan  untuk menggantikan gigi yang sudah copot di daerah rahang depan atas (maksila anterior). Ada beberapa kelebihan yang diberikan oleh gigi tiruan yang ditopang implant gigi bila dibandingkan dengan pemakaian crown dan sistem jembatan yang biasa atau gigi palsu lepasan, antara lain: tulang yang tersisa jadi terpelihara dan terjaga, membersihkan gigi implant lebih ...

Betulkah implant gigi mematikan?

TIDAK. Implant gigi modern ditemukan dan diterapkan dari sekitar taun 1965. Terhitung dari tahun tersebut sampai tahun tulisan ini dibuat (2018) atau selama lebih dari setengah abad, tidak ada satu pun pasien implant gigi meninggal jagat karena implan gigi. Implan gigi tidak terbukti mematikan dalam lebih dari setengah abad belakangan ini. Selama prosedur perawatan implant diikuti oleh dokter gig...

Membersihkan gigi implant ribet nggak?

TIDAK. Membersihkan implan gigi itu mirip kayak membersihkan gigi natural. Biasa saja. Pembersihannya meliputi: Sikat gigi. Pasien disarankan untuk menyikat gigi setiap kali habis makan. Menyikat gigi sekurang-kurangnya 2x sehari pada pagi hari dan malam hari sebelum tidur. Obat kumur. Gunakan obat kumur setelah menggosok gigi. Obat kumur berguna untuk membasmi bakteri yang masih tersisa da...

Benarkah semua dokter bisa memasang implant gigi?

TIDAK. Dokter yang diperbolehkan untuk menanam implan gigi adalah dokter gigi yang punya izin untuk melakukan operasi tanam implant gigi dan dokter spesialis bedah mulut. Tidak sembarang dokter boleh melakukan operasi tanam implant gigi. Dokter yang memasang implant gigi diharuskan punya izin atau lisensi melakukan operasi tanam implan gigi. Lisensi ini diperoleh usai mengikuti ujian dan pendidik...

Benarkah implant gigi gampang copot?

TIDAK. Tulang rahang menempel kuat pada titanium implan lebih kuat daripada lem super. Apalagi uliran implan mengunci implan ke tulang. Asalkan implan jadi dan dirawat dengan baik, implan bisa tahan belasan tahun sampai puluhan tahun. Proses berpadunya tulang dengan titanium disebut dengan nama "oseointegrasi". Lebih rinci tentang oseintegrasi bisa Anda baca dalam posting oseointegrasi. Sulit di...

Pasang implant gigi itu sakit apa tidak?

Seorang menunjukkan video tentang pemasangan implant gigi kepada saya. Saya baca, pengunggah video itu ingin menciptakan kesan seolah-olah pasien implan gigi merasa kesakitan yang teramat sangat kala proses pemasangan implant ke dalam gusi. Kata-kata yang biasanya dipakai seperti "Bayangkan betapa sakitnya" atau sejenisnya. Ada hoax samar dalam propaganda negatif itu. Seorang yang saya sebutkan d...

Berapa biaya implant gigi jika banyak gigi yang co...

Tanya Jika gigi banyak yang copot berapa biaya yang dikeluarkan untuk tanam gigi? Jawab Jawaban untuk pertanyaan tersebut bergantung pada sekurang-kurangnya 3 hal, yaitu: Banyak yang dimaksud itu berapa buah gigi? Apakah maksudnya 8 gigi atau lebih? Ataukah "hanya" 3? Ini perlu dipastikan lebih dulu karena banyak menurut seorang bisa berbeda dengan banyak menurut orang lain. Tentu saja harg...

Apa crown gigi punya efek samping/ risiko?

Perawatan crown gigi tergolong perawatan yang aman bagi pasien dan tidak membahayakan nyawa manusia. Perawatan ini punya potensi efek samping/ risiko yang rendah dan umumnya bisa diantisipasi. Berikut ini beberapa efek samping / risiko yang bisa terjadi dalam perawatan crown. Alergi Umumnya pasien tidak punya alergi terhadap bahan crown tapi ada sedikit pasien yang alergi dengan bahan-bahan...

Bahan dan metode evaluasi implant (2)

Standar ISO 10993 menunjukkan bahwa tipe penilaian bisa bebas dipilih untuk mengetes sitotoksisitas.Standar disajikan dalam empat kategori tipe penilaian, termasuk di antaranya penilaian morfologi sel dan pengukuran beberapa parameter sel. Standar yang sama juga menspesifikasi katalog bahan. Metode dan teknik yang diadopsi oleh laboratorium harus sederhana, dapat direproduksi, dan bisa diterapkan ...

Bahan dan metode evaluasi implant (1)

Standar pengetesan implant biomateri implant yang paling populer adalah ISO 10993 dalam bagian yang didedikasikan untuk tes in vitro (bagian ke-5). Bagian ini tidak menspesifikkan parameter yang paling penting untuk pengetesan sitotoksisitas, tapi hanya mendaftar karakteristik dan properti tertentu yang bisa dikejar selama alur evaluasi perilaku biomaterial in vitro. Hal tersebut memungkinkan labo...

Organisasi standar implant internasional

Beberapa organisasi berikut ini menjadi rujukan sehubungan dengan standar pengujian dan bagaimana cara menyiapkan sampel untuk pengujian implant in vitro, termasuk: Organization for Standardization (ISO) : Organisasi Standar Internasional Ente Nazionale Italiano di Unificazione (UNI) : Badan Standar Nasional Italia British Standards Institute (BSI) : Institut Standar Inggris Deutsches In...

Pengujian implant sebelum aplikasi

Pada umumnya, sistem sel yang terisolasi punya sensitivitas yang lebih tinggi kala kontak dengan bahan/ materi dari luar sistem natural dibandingkan dengan sistem jaringan tubuh. Hal ini termasuk bahan implan. Riset yang berhubungan dengan prakara ini dengan menerapkan beberapa metode yang praktis secara in vitro terus bertambah semakin banyak. Dengan adanya mekanisme penilaian toksisitas seluler...

Analisis antarmuka permukaan implant (2)

[Lanjutan] Lebih jauh, pada area jaringan tulang yang kurang dewasa, zona lapisan fibril kolagen termineralisasi ditemukan di antara tulang mineral dan lapisan padat elektron. Di samping itu, penggunaan TEM dengan voltase tinggi telah memampukan pelacakan kanalikulus yang mencapai permukaan implan. Untuk implant yang disemprot plasma dan replika implant plastik untuk implant yang disemprot dengan...

Analisis antarmuka permukaan implant (1)

Cukup sedikit analisis ultrastruktural tentang antarmuka implant tulang disajikan dalam literatur dibandingkan dengan total jumlah artikel yang menggunakan implant yang berjangkar pada tulang. Literatur yang paling banyak dipublikasikan mengevaluasi implant dengan permukaan dimesin atau permukaan halus yang serupa itu dengan menggunakan model replika implant plastik atau metode fraktur. Metode fr...

Ultrastruktural antarmuka implant - tulang

Dalam rangka dapat mengerti lebih jauh tentang mekanisme pengikatan yang terjadi antara jaringan tulang yang hidup dan permukaan implan, peneliti perlu memakai alat-alat analisis dengan resolusi yang cukup untuk analisis ultrastruktural. Hal ini secara khusus penting seiring dengan kemunculan teknologi permukaan implant yang berstruktur nano. Lagipula, bukan hanya aspek struktural saja yang perlu...

Respon jaringan terhadap modifikasi permukaan impl...

[Lanjutan] Performa implant gigi paling baik dievaluasi sehubungan dengan stabilitas implant ke dalam situs implan. Model ekspresi gen interfasial in vivo sukses dikombinasikan dengan analisis torsi pelepasan untuk menentukan kemungkinan hubungan antara peristiwa molekuler dan kekuatan torsi pada antarmuka. Peningkatan yang signifikan dan konstan pada torsi pelepasan didata untuk implant teroksid...

Respon jaringan terhadap modifikasi permukaan impl...

[Lanjutan] Paling cepat pada hari ketiga pasca penanaman implan, pengamat mendeteksi bahwa ekspresi puncak penanda osteogenik dan osteoklastik di permukaan implan. Pada kala yang sama, pengamat juga mendeteksi bahwa implant teroksidasi berkaitan dengan kenaikan tingkat ekspresi yang sangat tinggi dibandingkan implant dengan permukaan dimesin. Hal ini menunjukkan: Pemodelan ulang tulang di seki...

Respon jaringan terhadap modifikasi permukaan impl...

[Lanjutan] Pada permukaan implant tulang in vivo, perlekatan seluler dimediasi melalui lapisan yang karya protein. Sel-sel melekat pada lapisan itu menggunakan aneka reseptor permukaan, terutama membentuk keluarga integrin. Modulasi ekspresi integrin spesifik dapat mencerminkan perubahan-perubahan temporal dan konformasi spesifik dalam adsorpsi protein yang dipengaruhi oleh properti fisiko-kimia ...

Respon jaringan terhadap modifikasi permukaan impl...

[Lanjutan] Ekspresi kemokin, MCP-1, yang lebih tinggi di tulang terlihat pada implant dengan permukaan mesin dalam perbandingannya dengan implant oksidasi anoda. Ekspresi kemokin ini disertai dengan ekspresi sitokin TNF-α dan IL-1β yang juga lebih tinggi pada implant dengan permukaan mesin. Ekspresi sitokin TNF-α terjadi lebih tinggi pada 3 jam dan 1 hari setelah setelah implantasi. Ekspresi...

Respon jaringan terhadap modifikasi permukaan impl...

[Lanjutan] Kemajuan dalam teknologi riset terbaru memungkinkan para peneliti menerapkan teknik-teknik molekuler untuk menganalisis antarmuka antara jaringan hidup dan permukaan implan. Alat semacam itu dapat digunakan dengan tingkat presisi yang tinggi untuk menemukan mekanisme yang mengatur osseointegrasi termasuk kejadian inflamasi dini, sel induk mesenskim (MSCs) dan komunikasi sel dengan sel....

Respon jaringan terhadap modifikasi permukaan impl...

Oseointegrasi adalah hasil penyembuhan jaringan tulang yang menguntungkan di sekitar implant titanium. Ini adalah proses biologis di mana pembentukan jaringan tulang di sekitar implant membentuk penjangkaran langsung tanpa disertai pertumbuhan jaringan fibrosa pada antarmuka implant tulang (Branemark, Adell et al. 1969; Branemark, Hansson et al. 1977). Implan titanium banyak dipakai dan sukses b...

Permukaan disemprot plasma

Lapisan HA pertama kali diperkenalkan pada pertengahan dasawarsa 1980an untuk memperbaiki fiksasi antara tulang dan implan. Sejak kala itu, bahan ini telah banyak digunakan pada implant ortopedi dan gigi. Penyemprotan plasma komersial merupakan metode yang paling sering digunakan untuk pengendapan lapisan kalsium fosfat, seperti HA. Penyemprotan dilakukan ke bahan implant untuk meningkatkan bioa...

Metode persiapan lapisan CaP pada implant

Ada beberapa metode yang telah diperkenalkan untuk menyiapkan lapisan kalsium fosfat (CaP) pada implant gigi. Berikut metode-metode tersebut. Pengendapan semprotan plasma (spraying plasma deposition, deposisi SPD) Properti: 2D Tidak terdapat homogenitas kristalinitas Meningkatkan pertumbuhan tulang dan fiksasi yang kuat dan cepat secara in vivo dan klinis. Adhesi bakteri. Pen...

Lapisan kalsium fosfat pada implant titanium

Beberapa bahan permukaan reaktif telah menunjukkan kemampuan untuk membentuk ikatan kimia antar muka dengan jaringan sekitarnya melalui serangkaian reaksi biofisika dan biokimia sehingga memicu terjadinya 'fiksasi bioaktif' implan. Bahan bioaktif bisa biostabil (yaitu hidroksiapatit sintetis) atau bioresorbabel (yaitu kaca bioaktif dan keramik kaca). Beberapa keramik bioaktif seperti kaca bioakti...

Permukaan dilaser

Teknologi laser masih relatif baru. Teknologi laser di bidang implantologi dipakai untuk menghasilkan struktur 3 Dimensi pada level mikrometer dan nanometer. Metode laser dipilih untuk menghasilkan geometri permukaan yang kompleks. Teknik yang digunakan menghasilkan pulsa cahaya pendek dengan panjang gelombang tunggal sehingga menghasilkan energi yang terfokus pada satu titik. Metode ini berlangs...

Permukaan anodisi

Permukaan anodisi (TiUnite) adalah kristalin parsial dan titanium oksida yang diperkaya fosfat yang punya ciri berupa permukaan mikrostruktur dengan pori-pori terbuka pada kisaran mikrometer rendah (lihat gambar). Anodisasi atau oksidasi anodik, sebagaimana namanya, adalah proses elektrokimia yang dilakukan dalam elektrolit. Properti struktural dan kimia dapat disesuaikan dengan aneka ragam p...

Implan permukaan SLA

Implan-implan gigi yang tersedia secara komersil biasanya disembur dengan partikel lalu dietsa dengan asam. Kombinasi dua metode ini (metod SLA) dipakai untuk memperoleh kekasaran permukaan ganda dan untuk menghilangkan partikel-partikel yang menempel pada permukaan implant dari proses penyemburan partikel (sandblasting). Etsa asam mengurangi puncak yang terlalu tinggi, menghasilkan lubang yang le...

Perlakuan etsa asam

  Kekasaran permukaan implant yang diperoleh dengan metode etsa asam bergantung pada bahan implan, struktur mikro permukaan, asam dan waktu perendaman. Permukaan diaangap kasar minimal jika telah mencapai nilai Sa antara 0,3 sampai 1,0 μm. Analisis terhadap lapisan permukaan telah dilakukan, tapi masih sedikit. Lapisan hibrida titanium bisa terbentuk karena keberadaan ion hidrogen pada asam...

Permukaan implant generasi pertama

Generasi pertama implant yang sukses berpadu dengan tulang punya permukaan yang relatif halus hasil dari pemrosesan dengan mesin (Branemark et al. 1969). Permukaan implant mesin hanya sedikit berubah dan dianggap tidak kasar (lihat gambar). Apabila dilihat tanpa bantuan mikroskop, permukaan implant macem pertama tersebut terlihat halus, kekasarannya tidak terlihat. Sejak kesuksesan implant moder...

Kekasaran permukaan implant titanium

Para peneliti di bidang implantologi telah mengidentifikasi kekasaran permukaan implant gigi sebagai parameter yang penting bagi implant dan kapasitas implant untuk dapat berjangkar pada jaringan tulang. Metode manufaktur implant gigi dengan aneka permukaan ada bermacam-macam. Metode-metode ini berguna untuk meningkatkan kekasaran permukaan implan. Moetode yang plaing umum dipakai dalam manufaktu...

Teknologi mikro dan nano dalam implantologi

Teknologi mikro dan nano berkembang pesat pada abad 21 Masehi. Teknologi ini punya peran besar dalam memajukan dengan cepat teknologi rekayasa permukaan implant dalam bidang kedokteran gigi implan. Kemajuan di bidang teknologi rekayasa permukaan menghasilkan properti permukaan yang makin rumit pada skala mikro maupun nano. Properti yang terlibat ada banyak, termasuk properti morfologi, kimia, stru...

Implan generasi kedua terbukti lebih cepat dan leb...

Titanium murni dan titanium yang dipadukan dengan logam lain telah lama menjadi bahan standar mapan untuk memproduksi implant gigi karena logam ini punya kombinasi kekuatan mekanik, stabilitas kimia, dan biokompatibilitas yang menguntungkan. Paduan implant titanium dengan tulang yang berada di sekitarnya sangat penting untuk mencapai kesuksesan regenerasi dan penyembuhan tulang pasca operasi impla...

Penanaman implant dengan teknik lateralisasi saraf...

Lateralisasi saraf alveolar inferior adalah teknik baru. Dalam literatur implantologi, teknik tersebut adalah  teknik lateralisasi total bisa dipakai dalam bidang prostesis gigi, misalnya untuk menangani perkara ompong rahang bawah posterior ketika tulang alveolar mengalami penyusutan dan prostesis menekan saraf di daerah foramen. Teknik lateralisasi saraf alveolar inferior bisa pula dipakai dal...

Garis besar prosedur implant

Implan gigi memberi lebih banyak keuntungan dibandingkan gigi palsu lepasan atau gigi palsu cekat. Implan tidak tergelincir dan juga tidak berpotensi membatasi makanan yang dimakan oleh pasien, kecuali makanan yang terlalu keras, terlalu panas, dan terlalu asam. Jika cocok dengan pasien, implant adalah metode yang paling mampu mengembalikan fungsi gigi yang hilang ke kondisi yang mirip dengan asl...

Implan gigi mempertahankan kesehatan gigi di sekit...

Implan gigi adalah pengganti gigi akar gigi yang hilang dan pengganti akar tersebut ditanam dengan cara bedah. Implan ditanam dalam tulang rahang dan bertindak sebagai jangkar untuk gigi pengganti yang dikenal sebagai mahkota atau set lengkap gigi pengganti. Implan gigi telah menjadi pilihan perawatan yang bisa diprediksi untuk memulihkan gigi yang hilang. Tujuan bedah implant gigi adalah untuk m...

Reposisi saraf alveolar inferior dalam operasi imp...

Pemasangan implant gigi pada rahang bawah posterior dengan resorpsi yang parah bisa menimbulkan kerusakan pada saraf alveolar inferior. Teknik reposisi saraf telah dipakai untuk menciptakan peluang agar pemasangan implant gigi dengan panjang yang memadai bisa sukses dalam kasus semacam ini. Dalam kasus punggungan mandibula posterior atrofi, teknik reposisi saraf alveolar inferior jadi alternatif ...

Saraf alveolar inferior penting dalam perawatan im...

Anatomi jalur saraf alveolar inferior sangat penting bagi dokter gigi, dokter saraf, radiolog, dan patolog guna membantu diagnosis, penanganan, perencanaan bedah, dan penerapan anestesia lokal. Demikian disampaikan oleh Polland et al. dalam penelitiannya pada tahun 2001.  Kerusakan saraf alveolar inferior menghasilkan dampak yang negatif pada kualitas sensibilitas fasial dan kemampuan pasien unt...

Apa beda implant gigi dengan gigi palsu permanen?

Bedanya, implant gigi atau gigi palsu tanam adalah bahasa kedokteran gigi, sedangkan gigi palsu permanen adalah bahasa pemasaran. Modus perawatan dan benda yang dimaksud oleh dokter dan oleh marketer itu sama, yaitu menanamkan akar gigi palsu ke dalam tulang rahang, kemudian mahkota gigi palsu dipasang di atas akar palsu tersebut. Apakah implant gigi betul-betul permanen? Permanen dalam arti apa...

EYD bidang kedokteran gigi implant

Ejaan yang benar: implan  implant Ejaan yang salah emplam impla implam implaan impland impelan inplan inplant inpland inpla inpelan impan inpan implat inpat inflan imflan imvlan imvlant inflant infland imvland infand invand implans Ejaan yang benar: titanium  Ejaan yang salah: titanoum titanum tatinium tittanium ...

Implan dengan kekasaran nano

Memasuki abad 21 Masehi, para pakar implan gigi mengintensifkan penelitian tentang permukaan implant dengan tingkat kekasaran nano meter. Ada peluang bahwa permukaan berukuran nano akan meningkatkan perawatan implan. Hasil dari penelitian di bidang implantologi gigi menunjukkan lapisan kerja TiO2 dengan skala submikro/ nano dengan ukuran pori lateral 20-160 nm bisa dihasilkan dengan cepat pada ...

Permukaan implant dengan perlakuan fluorida (2)

[Lanjutan] Ada hubungan antara respon seluler dan konsentrasi ion F. Untuk konsentrasi dari 25 sampai 200 ngF-/mL, yaitu sampai ambang toksisitas, ada peningkatan linier kalsium intraseluler. Jika konsentrasi naik dari 500 hingga 1000 ngF-/mL, kalsium intraseluler turun hingga level yang lebih rendah daripada konsentrasi dalam kisaran 100 ngF-/mL. Efek selular tersebut terjadi untuk paparan ion fl...

Permukaan implant dengan perlakuan fluorida (1)

Kita semua telah mengetahui bahwa ion fluorida punya kapasitas yang meningkatkan pembentukan tulang. Kapasitas ini berfungsi meningkatkan kalsifikasi tulang. Salah satu karakteristik fluorida adalah watak bifase (fase ganda). Fluorida menghasilkan efek yang menguntungkan bila dipakai dalam konsentrasi rendah, tapi fluorida punya efek beracun bila dipakai dalam konsentrasi tinggi. Dalam dosis t...

Semburan partikel pada permukaan implant gigi

Partikel yang dipakai untuk menyembur implan antara lain silikon oksida (silika), aluminium oksida (alumina), titanium oksida (rutil), hidroksiapatit, dan kalsium fosfat. Permukaan implant akan mengalami deformasi mikro plastis ketika partikel-partikel tersebut menghantam permukaan implan. Proses penyemburan dengan partikel dikenal dengan nama "sandblasting" dalam bahasa Inggris. Proses ini mel...

Permukaan implant dengan perlakuan etsa asam

Permukaan implan gigi bisa dibuat agar punya kekasaran mikro dengan menggunakan metode etsa asam. Metode etsa asam menghasilkan aneka morfologi kekasaran yang dangkal bergantung pada kondisi perlakuan yang meliputi: persentase komposisi kimia jenis asam yang dipakai waktu etsa suhu Etsa asam memungkinkan manusia untuk mengkontrol kekasaran permukaan implan, jumlah, ukuran, dan distrib...

Implan laser & plasma (2)

[Lanjutan] Perlakuan permukaan implant menggunakan semprotan plasma dan laser menghasilkan pengerutan makro. Hal ini membuat implant plasma dan laser jadi tidak lagi dipakai pada abad 21 Masehi sekarang ini.  Karakteristik permukaan implant diharapkan menunjukkan pengaruh biologis selama pemasangan implan dan selama berinteraksi dengan sel-sel. Permukaan implant diharapkan memodifikasi mekanis...

Implan laser & plasma (1)

Ada dua perlakuan permukaan alternatif yang meliputi ablasi laser dan penyemprotan dengan plasma (plasma spraying). Setelah dua perlakuan tersebut, permukaan implant akan mempunyai tingkat kekasaran yang tinggi. Tingkat kekasaran yang dihasilkan dengan teknik ini tergolong dalam tingkat kekasaran makro.  Kekasaran makro berpengaruh pada stabilitas implant dan fiksasi mekanis pembentukan tulang. ...

Perlakuan permukaan implant (3)

Penelitian-penelitian yang telah dilakukan di bidang implantologi juga berhasil menunjukkan sejumlah variabel, kombinasi parameter yang punya keterkaitan dengan perlakuan permukaan implan, dan faktor-faktor tertentu punya pengaruh yang signifikan pada proses pemaduan implant dengan tulang. Faktor-faktor tertentu yang dimaksud meliputi: materi implan bentuk implan permukaan implan kuant...

Perlakuan permukaan implant (2)

[Lanjutan] Kekasaran permukaan implan gigi bisa dianalisis dari tiga sisi, yaitu: kekasaran makroskopik kekasaran mikroskopik kekasaran nano Setiap ukuran kekasaran menyediakan kontak dengan sel yang berbeda dan molekul biologi yang berbeda. Masing-masing kekasaran tersebut bertanggungjawab untuk intensitas dan tipe ikatan biologis. Peningkatan luas permukaan implant diharapkan mening...

Perlakuan permukaan implant (1)

Penelitian-penelitian di bidang implantologi telah banyak mengembangkan pendekatan modifikasi permukaan implant untuk semua kelas implant gigi. Tujuan dari penelitian pengembangan implant itu adalah untuk memodulasi respon biologi dan meningkatan oseointegrasi dan stabilitas primer implant pada dudukannya di tulang rahang. Penelitian permukaan implant biasanya multi disiplin, seperti Sains Mater...

Pengaruh permukaan implant pada pemaduan implant d...

[Lanjutan] Selama insersi implan dan segera setelah permukaan implan bersentuhan dengan darah, protein yang berasal dari darah menutupi permukaan implan. Titanium yang bersentuhan dengan lingkungan fisiologis mengabsorbsi molekul-molekul dari plasma serta mengabsorbsi faktor I, faktor III, Ig G dan C1g. Beberapa detik setelah itu, permukaan implant dilekati dengan polimorfonuklir granulosit dan...

Pengaruh permukaan implant pada pemaduan implant d...

Implan dibuat dari biomateri. Biomateri yang paling umum dipakai untuk membuat implan gigi adalah titanium. Meskipun titanium telah banyak dipakai sebagai bahan implan, beberapa pakar masih bertanya-tanya tentang bagaimana prosedur yang paling tepat untuk menghasilkan respon biologi yang paling baik. Ketika menganalisis pentingnya permukaan implant untuk terjadinya oseointegrasi, kita hendakny...

Apakah tulang rahang tipis bisa implant?

Tergantung setipis apa rahang Anda dan apakah tulang rahang tipis itu masih bisa diperbesar dengan prosedur augmentasi tulang atau tidak. Apabila tipisnya hanya sedikit tipis, mungkin masih ada diameter implant standar yang bisa masuk ke rahang Anda. Diameter implant standar itu tidak cuma satu macam. Kisarannya cukup lebar. Dokter akan memeriksa apakah tulang rahang Anda masih memungkinkan un...

Pengaruh tulang pada kesuksesan implant gigi

Implan itu kenal cocok. Tantangan perawatan implant bukan hanya operasi implan. Sebelum operasi implan, tantangan cukup besar telah tersaji yaitu menentukan implant mana yang paling cocok dengan kondisi pasien. Karena tidak ada pasien yang sama persis, maka tidak ada rumus eksak a la matematika yang bisa dipakai. Pemilihan implant mana yang cocok bagi pasien antara lain ditentukan oleh finishi...

Keterbasahan implant

Keterbasahan permukaan implan gigi memengaruhi derajat kontak implant dengan lingkungan fisiologis. Permukaan implant yang sangat hidrofilia terlihat lebih menguntungkan daripada permukaan yang hidrofobia bila menimbang interaksi implant dengan cairan biologis, sel, dan jaringan dalam tubuh manusia.  Pelembaban sepenuhnya dan distribusi cairan pada permukaan implant mengindikasikan energi permuk...

Pengaruh permukaan implant pada stabilitas primer ...

[Lanjutan] Penelitian Santos et al. (2009) menganalisis pengaruh permukaan implan gigi pada stabilitas primer. Hasil penelitian timnya menunjukkan bahwa torsi maksimal untuk menyisipkan implant ke posisinya bergantung pada faktor koefisien friksi antara permukaan implant dan dinding lubang dudukan implan, desain implan, geometri ulir implan, dan perlakuan permukaan implan. Untuk permukaan finishi...

Pengaruh permukaan implant pada stabilitas primer ...

Javed dan Romanos (2010) mengevaluasi peran stabilitas primer untuk kesuksesan pemberian beban langsung pada implant yang baru dipasang. Analisis ini penting karena prasyarat fundamental kesuksesan implant adalah stabilitas primer yang substansial pada waktu penyisipan implant dan setelah pemberian beban pada implan. Hal ini bisa dianggap sebagai prinsip pemersatu di balik kebutuhan akan kec...

Diagnosis & penanganan kesehatan implant gigi (2)

B. Scaling and root planing (Pengikisan dan pengetaman akar gigi) [Lanjutan] Prosedur Scaling and root planing lebih dikenal dengan nama "skeling" saja alih-alih terjemahannya. Prosedur skeling memerlukan penggunaan kuret berbahan plastik dan pasta pemoles yang halus untuk pemeliharaan kesarasan implan.   Pemeliharaan implant secara profesional harus mencakup penghapusan deposit lunak dan depos...

Penilaian kesehatan implant (4)

9. Oklusi [Lanjutan] Skema oklusal hendaknya memberi dukungan posterior yang memadai pada dimensi vertikal oklusal yang tepat. Panduan eksentrik hendaknya dipakai untuk memastikan efek yang berpotensi merusak dari parafungsi oklusal yang menyimpang agar terdistribusi secara optimal. Jika terjadi komplikasi teknis, maka komplikasi-komplikasi tersebut harus dirawat dengan tepat sesuai kondisi ka...

Diagnosis & penanganan kesehatan implant gigi (1)

Diagnosis Kesarasan Apabila tanda-tanda klinis inflamasi tidak terdeteksi, maka pasien implant diklasifikasi saras. Mukositis implan Mukositis adalah lesi inflamasi lokal dalam jaringan lunak tanpa penyusutan tulang progresif, terpisah 0,2 – 2 mm kawah yang terjadi segera setelah memasang abutment di sekitar implant yang telah sukses berpadu dengan tulang. Mukositis bisa diidentifikasi se...

Penilaian kesehatan implant (2)

[Lanjutan] 3. Kedalaman Probing Klinis Probing adalah parameter penting yang handal untuk pemantauan longitudinal jaringan lunak peri-implan. Prosedur untuk probing yang aman di sekitar restorasi implant telah ditegakkan. Prosedur tersebut tidak mengganggu integritas implant dalam mulut. Apabila memungkinkan, tindakan probing periodontal bisa dilakukan dari bagian tengah permukaan fikstur pada...

Penilaian kesehatan implant (1)

Penilaian kesarasan implant oleh dokter gigi implant meliputi sekurang-kurangnya prakara berikut ini. Pembaruan sejarah medis dan sejarah gigi Dokter melakukan penilaian kesarasan implant dalam mulut pasien dimulai dari memperbarui sejarah medis dan sejarah gigi pasien. Hal ini dilakukan untuk memastikan bahwa dokter mengetahui semua kondisi dan terapi yang menyertai. Di samping itu, pembaru...

Pasien sakit ginjal menerima implant gigi, bisakah...

Bisa jika kondisi ginjal Anda terkontrol dengan baik dan tergantung seberapa parah penyakit ginjal yang Anda derita juga. Ada baiknya Anda lebih dulu konsultasi dengan dokter yang menangani ginjal Anda. Meskipun begitu, Anda perlu sadar bahwa kriteria penerima implant adalah kondisi tubuhnya saras tanpa penyakit sistemik. Penyakit ginjal adalah penyakit sistemik. Efek dari kriteria kesarasan ya...

Indeks plak untuk implant gigi

Berikut ini tabel indeks plak yang umum dipakai untuk mengevaluasi plak pada implant gigi. Tabel 1 Indeks plak yang umum dipakai untuk evaluasi implant gigi O'Leary dan rekan1 % skor = jumlah permukaan gigi yang ada plaknya/ jumlah permukaan gigi yang ada x 100 Lindquist dan rekan2 0 = tidak ada plak yang terlihat 1 = akumulasi plak lokal 2 = akumulasi plak umum ...

Penilaian kesehatan implant (3)

5. Nanah [Lanjutan] Dalam laporan kasus, nanah berkaitan dengan gangguan kesarasan jaringan peri-implan. Nanah menunjukkan adanya infeksi peri-implantitis pada jaringan peri-implan. Tapi, spesifisitas dan sensitivitas nanah sebagai penanda untuk peri-implantitis tahap mula atau tahap lanjut belum dipastikan. 6. Stabilitas margin jaringan lunak Probing peri-implan hendaknya mencakup penentuan l...

Perawatan implant gigi perlu tindak lanjut

Prosedur pemasangan implan gigi yang sukses adalah permulaan dari langkah tindak lanjut implan. Pasien yang terapi implannya sukses masih perlu menerima perawatan pendukung secara berkelanjutan, sistematis, dan individual. Perawatan ini terutama ditujukan untuk merawat jaringan peri-implan. Pasien penderita edentia parsial atau periodontitis kronis yang sudah ada sebelum perawatan implant punya ...

Berapa kisaran harga implant gigi murah di Jakarta...

Apakah implan gigi yang Anda maksud itu benda yang bernama implant giginya saja?  (Lihat gambar di atas) Ataukah maksud Anda implan gigi komplet termasuk mahkota dan abutment sudah termasuk pemasangan beserta layanan-layanan lain yang diperlukan? Kalau maksud Anda hanya benda implan gigi saja, kisaran harganya ada yang 3 juta dan 5 juta. Harga di atas itu juga ada. Tapi, apakah guna benda im...

Kekasaran permukaan implant faktor sukses implant ...

Nilai rata-rata ± simpangan baku kekasaran permukaan silinder titanium parameters adalah sebagai berikut: Pemrosesan mesin Ra (µm): 0.65+0.11  Rq (µm): 0.81+0.17  Rz (µm): 6.09+0.37  Rmax (µm): 7.76 + 1.37 Rpkx (µm): 21.6+0.41 A1 (µm²): 24.71 + 5.42 A2 (µm²): 70.66+16.20 Asam Ra (µm): 0.51+0.10 Rq (µm): 0.71+0.07 Rz (µm): 5.09+0...

Implan gigi emas, mungkinkah?

Mungkin banget! Gigi implan terdiri dari akar gigi buatan, abutment, dan mahkota. Akar gigi buatan terbuat dari titanium. Pasak akar tersebut ditanam dalam tulang rahang. Di bagian atasnya diberi abutment untuk menghubungkan akar buatan dan mahkota gigi. Pada bagian paling atas, dipasang mahkota gigi. Mahkota gigi bisa dibuat dari aneka bahan. Untuk kebutuhan implant gigi, bahan yang banyak di...

Kekasaran permukaan implant faktor sukses implant ...

(Lanjutan) Definisi parameter kekasaran permukaan  yang utama adalah sebagai berikut ini: Ra (kekasaran rata-rata): Ra adalah nilai rata-rata amplitudo sehubungan dengan garis referensi. Parameter ini mengkuantifikasi jarak vertikal rata-rata antara lima puncak tertinggi dan lima lembah besar.Rq atau Rms (kekasaran rerata akar kuadrat): Rq adalah akar kuadrat dari kuadrat amplitudo sehubung...

Kekasaran permukaan implant faktor sukses implant ...

(Lanjutan) Kekasaran permukaan implant dicirikan dengan tonjolan kecil-kecil (puncak) dan lubang kecil-kecil (lembah) pada permukaan implant dalam hubungannya dengan bidang datar yang jadi referensi (bidang referensi). Parameter-parameter yang dipakai untuk mengkuantifikasi kekasaran ini ditentukan dalam dua dimensi (2D) atau tiga dimensi (3D). Aksara R dipakai untuk parameter-parameter yang berk...

Kekasaran permukaan implant faktor sukses implant ...

(Lanjutan) Bentuk umum permukaan implant itu tidak beraturan. Bentuk tidak beraturan bisa dari kekasaran dan bentuk permukaan yang bergelombang. Bentuk sering dihasilkan dari error pada  jalur pemandu mesin dan deformasi karena pola stres yang mengenai komponen.Karena tipe dasar geometri permukaan dihasilkan oleh faktor yang berbeda-beda dan cenderung punya hubungan yang berbeda dengan perfo...

Kekasaran permukaan implant faktor sukses implant ...

Albrektsson et al. pada tahun 1981 pertama kali menunjukkan pentingnya topografi permukaan implant untuk kesuksesan osteointegrasi implant gigi. Penelitian-penelitian yang lebih baru menegaskan saran Albrektsson bahwa kekasaran permukaan implant memengaruhi osteointegrasi dan stabilitas mekanik implant gigi. Beberapa mekanisme yang terlibat dalam proses osteointegrasi bergantung pada morfologi...

Risiko dan Penanganan Komplikasi Implan Gigi

Implan gigi adalah teknologi baru yang paling tepat untuk mengganti gigi yang hilang. Alasannya, gigi implant punya fungsi dan tampilan yang mirip gigi natural, tampak kokoh, dan tidak merusak gigi sekitar. Meski demikian, pemasangan implan gigi mengandung risiko komplikasi yang dapat menyebabkan kegagalan, seperti yang ditemukan dalam beberapa kasus pemasangan implant gigi. Risiko tersebut melipu...

Tipe implant gigi (2)

Pada mulanya, prostesis terdiri dari tujuh bagian, yaitu: implan, perantara, sekrup tengah, tiruan, sekrup prostesis, baut abutment dan prostesis. Namun, pengalaman klinis telah menunjukkan bahwa semakin banyak jumlah komponen, semakin sedikit peluang sukses.Saat ini, prostesis yang disemen terdiri dari empat elemen: implan, abutment, fiksasi sekrup abutment, dan mahkota prostesis. Prostes...

Tipe implant gigi (1)

Tidak ada kesepakatan di antara peneliti mengenai kekasaran permukaan terbaik dan bentuk implant terbaik. Ada beberapa macem implan gigi yang tersedia di pasaran. Produsen yang sama memproduksi implan dengan berbagai bentuk dan permukaan. Bentuk geometris implant harus dipilih sedemikian rupa agar memberi wilayah kontak tulang-implan yang terbesar guna meningkatkan osteointegrasi dan men...

Produk implant gigi yang aman itu seperti apa?

Produk implan gigi merujuk ke bagian akar tiruan dari gigi implan. Umumnya bentuknya berulir menyerupai sekrup. Perawatan implant yang aman bukan hanya memerlukan dokter gigi implant yang punya latarbelakang pendidikan implant dan punya jam terbang implant yang tinggi, tapi juga produk implan gigi yang aman. Produk implant yang aman itu yang bagaimana?Standar internasional (ISO-10993)Implan perlu ...

Berapa lama proses implant gigi yang paling cepat?

15 menit untuk kasus yang paling mudah jika yang Anda maksud hanya operasi menanam pasak implant ke dalam tulang rahang saja.20 menit-30 menit untuk kasus umumnya dan 60 menit sampai 120 menit untuk kasus yang rumit. Tapi ini juga hanya operasi penyisipan implan gigi ke dalam tulang rahang saja. Tidak menghitung tahap skrining, tahap perencanaan, masa penyembuhan, dan sebagainya.Jika proses imp...

Apa bisa gigi implant untuk gusi yang sudah menipi...

Tergantung seberapa tipis.Kalau tipisnya gusi dikarnakan resesi tulang dan masih memungkinkan untuk diperbesar dengan bone graft, implan gigi masih memungkinkan untuk dipasangan asalkan bone graft jadi. Prosedur bone graft atau cangkok tulang memberi Anda peluang untuk memperbesar tulang Anda. Jika perawatan ini sukses, tulang akan jadi lebih besar sehingga cukup untuk menopang implan. Bone gra...

Setelah gigi rusak dicabut, kapan bisa pasang impl...

Bisa langsung dipasang implan gigi kala itu juga di lubang bekas gigi yang dicabut. Alternatif lainnya, Anda bisa menunggu 2 minggu sampai 3 bulan setelah gigi dicabut atau menunggu sampai sekitar 8 - 10  bulan setelah gigi dicabut agar bekas gigi dicabut sembuh, baru kemudian menerima pemasangan implant gigi. A. Langsung pasang implan begitu gigi selesai dicabutKelebihanMengurangi waktu pera...

Mungkinkah implant gigi bisa lepas?

Implan gigi tidak mungkin lepas jika tulang rahang penopang implan gigi masih utuh dan masih terkunci pada tulang dengan penguncian bioaktif dan penguncian mekanis. Implan gigi mungkin lepas jika ketentuan tersebut di atas tidak terpenuhi. Kondisi yang mungkin terjadi:Tulang rahang penopang implant mengalami penyusutanImplan kokoh tertanam dan bisa dipakai karena tersedia jumlah tulang berkual...

Implan gigi harga 3 juta, ada kah?

Ada dong, tapi pasak implant giginya saja, belum termasuk abutment, mahkota (crown), pemasangan, penanganan komplikasi (jika terjadi), dan layanan-layanan lain.  Perlu Anda tahu, umumnya implan gigi itu benda yang bentuknya mirip seperti sekrup. Begini nih: Ada aneka desain implant gigi, antara lain, desain implant silinder. Desain silinder pun masih macam-macam. Nah, inilah yang disebut...

Kesuksesan implant perlu lapisan oksida titanium (...

Meneliti pengaruh titanium oksida pada osteointegrasi itu tidak mudah. Tantangan terutama dari penelitian ini adalah bagaimana caranya mengisolasi variabel-variabel yang mencirikan permukaan, kemudian menganalisis variabel-variabel itu satu per satu. Sebagai contoh, dalam suatu penelitian perlu untuk mengubah jenis lapisan oksida (struktur kristal) tertentu saja sambil mempertahankan kek...

Kesuksesan implant perlu lapisan titanium oksida (...

Titanium digunakan secara luas dalam pembuatan implan gigi sejak permulaan dasawarsa 1970-an. Walaupun begitu, para pakar implant masih belum menjelaskan sepenuhnya tentang bagaimana sebetulnya mekanisme yang terlibat dalam respon biologis yang membuat implant bisa bersatu padu dengan tulang.Titanium punya karakteristik membentuk lapisan oksida titanium yang sangat tipis pada permukaannya...

Berapa lama proses implant gigi?

Pasang implan gigi cuma perlu waktu 20 menit untuk kasus yang mudah. Lalu, kenapa ada yang bilang perlu waktu 3-4 bulan? Apanya yang lama? Karena menghitung proses dari pertama kali Anda datang untuk konsultasi sampai tuntasnya seluruh rangkaian proses-proses perawatan Proses skrining dan perencanaan berlangsung sekitar 1 hari, satu kali pertemuan. Ini kunjungan pertama Anda ke klinik sambil meny...

Prosedur implant pembebanan langsung

Di antara beberapa prosedur implan, ada prosedur yang memungkinkan penanaman implan dan pemasangan prostesis dilakukan sekali jalan. Prosedur ini disebut prosedur pembebanan langsung (immediate loading dental implant procedure). Tidak semua pasien implant cocok menerima prosedur ini. Lagipula, risiko lebih tinggi dan peluang sukses tidak setinggi prosedur yang lebih umum karena pembeban langsung ...

Kenapa implant tidak boleh bergerak?

Banyak peneliti telah menginvestigasi berbagai aspek pemaduan tulang dengan implan, suatu proses yang dikenal dengan nama "oseointegrasi". Banyak hasil yang telah diperoleh. Walaupun begitu, para peneliti masih punya keraguan tentang mekanisme mikro aktual yang terlibat dalam proses penyatuan titanium implant dengan tulang, terutama tentang perlu-tidaknya rangsangan mekanik untuk menginduksi ...

Bagaimana baiknya setelah operasi implant gigi?

Setelah operasi pemasangan implan gigi selesai dan Anda keluar dari ruang gigi, pastikan dulu pengaruh obat bius tidak menganggu konsentrasi Anda. Duduk beberapa menit di ruang tunggu sebelum pulang sampai Anda merasa pasti dengan prakara itu.Jangan menyetir mobil atau motor sendiri. Pengaruh obat bius mungkin masih tersisa dan bisa menggganggu refleks dan keseimbangan Anda kala menyetir mobil ...

Penguncian implant pada tulang

Dokter implant bisa menggunakan tes mencopot implan dengan torsi untuk melakukan penilaian klinis apakah ikatan kuat antara implan titanium dan tulang telah terbentuk dengan baik. Dalam analisis implan yang dicopot dari tulang hewan yang sebelumnya dipasangi implan, peneliti telah mengamati bahwa sejumlah besar tulang terlihat turut tercabut dan menempel dengan kuat pada permukaan i...

Respon tubuh terhadap biomateri implant gigi

Implan dibuat dari bahan yang punya kualitas bioaktif. Materi bioaktif tersebut mengikatkan implan ke jaringan tulang melalui jembatan kalsium dan fosfor. Adapun ikatan kimia antara implan titanium yang polos tanpa lapisan dengan jaringan tulang yang hidup terjadi melalui ikatan van der Waals dan ikatan hidrogen. Dua ikatan ini cukup lemah.Daya-daya van der Waals (polarisasi dan di...

Apakah implant gigi aman?

Implan gigi modern telah diterapkan pada manusia dari abad 20 hingga abad 21 sekarang. Kenyataannya, dalam rentang masa itu, tidak pernah kejadian pasien meninggal jagat karena implant gigi. Anda bisa memeriksa jurnal-jurnal kedokteran dari berbagai negara sedunia. Jurnal-jurnal ini umumnya tersedia gratis di internet. Laporan dari senden manapun di seluruh penjuru bumi juga tidak mencantumkan...

Pembentukan paduan implant gigi dengan tulang raha...

Bahan-bahan bioaktif (keramik kaca dan hidroksiapatit) menimbulkan reaksi-reaksi biologi yang spesifik di permukaan implant sehingga menghasilkan pembentukan paduan antara implan dan inang. Biomateri ini membentuk ikatan yang kuat dengan jaringan yang berdekatan. Bahan tersebut meningkatkan hubungan dengan jaringan tulang melalui jembatan kalsium dan fosfor. Titanium tidak cocok dengan ...

Interaksi jaringan dengan implant gigi

Implan gigi punya kemampuan untuk dapat menahan beban dalam mulut karena mengunci secara mekanis dan secara biologis ke dalam tulang rahang. Penguncian mekanik bukan bergantung pada bahan implan. Implan gigi tertambat dalam tulang seperti jangkar tertambat. Untuk implant gigi dengan bentuk seperti sekrup, beban aksial ditransmisikan ke tulang melalui ulirannya. Faktor-faktor yang memengaruhi...

Apa makanan yang aman dimakan setelah implant gigi...

Maksud Anda dengan "setelah implant gigi" itu apakah setelah operasi implan gigi atau setelah perawatan implan gigi selesai tuntas? 1. Setelah operasi implant gigiMakanan setelah operasi itu makanan cair/ lembek/ lunak. Intinya, makanan yang tidak bisa membuat implant bergerak andai makanan itu tanpa sengaja mengenai bagian bekas operasi. Pasien diinstruksikan agar makanan jangan sampai menge...

Berapa umur untuk memasang gigi implant?

Umur minimal pasang implant gigiImplan hanya bisa ditanam pada rahang yang telah berkembang penuh. Anak-anak tidak bisa menerima perawatan ini karena rahang anak-anak sedang berkembang sehingga makin lama makin besar. Rahang yang telah berkembang penuh tidak lagi bisa membesar. Perkembangannya sudah mentok, sudah maksimal. Rahang mencapai perkembangan maksimal pada kisaran umur antara 17 tahun hi...

Titanium & Vanadium pas untuk implant gigi

(Lanjutan) Tes in vivo dilakukan untuk mengevaluasi ketahanan korosi dan gangguan antara toksisitas, pembajakan (jaringan non-vaskular dan ketebalan jaringan yang kontak dengan implan, ketiadaan sel patologis) dan inersia (jaringan tervaskularisasi dan jaringan ikat longgar).Ada hubungan antara reaksi beracun dari bahan dan tingkat korosi yang tinggi. Co, Cu, Ni dan V menimbulkan peningkatan de...

Biokompatibilitas biomateri implant gigi

Konsep modern tentang biokompatibilitas bukan hanya melibatkan kompatibilitas materi dengan jaringan saja, tetapi juga kemampuannya untuk melakukan fungsi spesifik. Respon terhadap materi tertentu bisa berbeda pada lokasi yang berbeda. Oleh karena itu, biokompatibilitas didefinisikan hanya untuk penerapan tertentu di lokasi tertentu.Sebagai contoh, biomaterial yang dipakai dalam lensa intraok...

Waktu tanam dan penyembuhan implant gigi

Protokol klinis konvensional yang diusulkan oleh Brånemark untuk penempatan implan gigi melibatkan dua fase. Fase yang pertama adalah penanaman implan di lubang yang telah disiapkan pada tulang rahang. Protokol ini merekomendasikan periode penyembuhan reorganisasi jaringan.Waktu tunggu terjadinya penyembuhan bergantung pada kualitas tulang dan daerah pemasangan implan. Brånemark memberi kisa...

Tanam implant gigi

Implan gigi ditanam ke dalam tulang rahang untuk mengganti akar gigi asli agar memungkinkan pemasangan prostesis gigi. Implan menduduki posisi penting dalam abad 21 Masehi melalui karya Profesor Per Ingvar Brånemark yang meneliti mikrosirkulasi dalam jaringan tulang.Brånemark menggunakan benda optik baja tahan karat untuk menyelidiki anatomi dan fisiologi jaringan yang ceder...

Pertimbangan neurovaskular dalam implant gigi: Pen...

(Lanjutan) Penempatan implan gigi pada rahang bawah bagian belakang yang mengalami resorpsi parah dapat menyebabkan kerusakan pada saraf alveolar inferior. Teknik reposisi saraf digunakan untuk menciptakan peluang agar memungkinkan penyisipan implan gigi dengan panjang yang memadai dalam kasus-kasus tersebut. Dalam kasus dengan punggung rahang bawah belakang atrofi, teknik reposisi s...

Pertimbangan neurovaskular dalam implant gigi: Pen...

Anatomi jalur intra-tulang untuk saraf alveolar inferior sangat penting bagi dokter gigi, dokter spesialis saraf, radiolog, dan patolog untuk membantu mendiagnosis, merawat, merencanaan operasi, dan menerapkan anestesi lokal. Kerusakan saraf alveolar inferior berpengaruh negatif pada kualitas kepekaan wajah dan kemampuan pasien untuk mengubah pola perubahan kegiatan saraf menj...

Panas memengaruhi kesuksesan implant gigi

Kesuksesan implant gigi dalam bidang kedokteran gigi implan diketahui bergantung pada beberapa parameter yang bisa ditingkatkan dengan mempertimbangkan kriteria biologis dan mekanis. Untuk menjelaskan mekanisme mikro yang terlibat dalam proses osteointegrasi, kita perlu mengetahui tentang konsep-konsep biologi, fisiologi, anatomi, bedah, dan jaringan regenerasi. Osteointegrasi tel...

Implan berdiameter kecil

Penelitian-penelitian yang telah dilakukan di bidang kedokteran gigi pada masa lalu telah membahas beban oklusal fungsi implant gigi. Dengan demikian, implant dianjurkan berdiameter besar. Namun, ada pertimbangan lain yang mungkin perlu dipikirkan masak-masak karena memengaruhi keawetan implan. Parameter utamanya adalah pergeseran implan, beban oklusal yang berlebihan, dan lingkar perkutan.Ada...

Rehabilitasi prostetik implant gigi depan rahang a...

Setelah implant berpadu dengan tulang, tahap selanjutnya adalah rehabilitasi prostetik. Restorasi yang tidak tepat bisa menyia-nyiakan rencana pra-rawat yang baik dan pelaksanaan operasi pemasangan implant yang sukses. Jika implan gigi dipendam dalam gusi, maka proses restorasi dimulai setelah membuka jaringan lunak yang menutupi implan. Pada rahang atas bagian depan, membuka jaringan lunak pe...

Pelaksanaan pemasangan implant gigi depan rahang a...

Implan gigi perlu dipasang melalui operasi dengan cara yang benar. Hal ini perlu untuk memperoleh hasil estetik yang ideal. Hanya melalui perencanaan perawatan yang tepat saja maka posisi yang benar bisa diperoleh dan jumlah implant yang tepat bisa diketahui.Sebelum pemasangan implan gigi melalui operasi, dokter gigi implant perlu memastikan ketersediaan jaringan keras dan jaringan lunak dalam k...

Rencana pemasangan implant gigi depan rahang atas ...

(Lanjutan) CT scan juga bisa menunjukkan status plat tulang bukal di daerah edentula. Informasi ini penting sekali dan memengaruhi banyak langkah-langkah selanjutnya guna memperoleh hasil-hasil perawatan yang estetis. Jika pelat tulang bukal tidak ada, maka bone graft diperlukan sebelum pemasangan implant gigi. Graft tulang yang sukses akan menyediakan dukungan tulang yang diperlukan untuk stabili...

Rencana pemasangan implant gigi depan rahang atas ...

Langkah pertama dalam perencanaan perawatan untuk kasus implan gigi adalah menentukan hasil final yang diinginkan, khususnya hasil prostetik. Setelah hasil prostetik tervisualisasi dengan jelas, dokter kemudian bisa mengambil langkah-langkah purwa yang tepat untuk memenuhi kebutuhan pasien.Pendekatan ini sangat penting dalam zona estetik rahang atas bagian depan. Perencanaan melibatkan percakapa...

Tanam implant gigi depan rahang atas

Implan gigi layak digunakan sebagai pilihan perawatan untuk mengganti gigi depan rahang atas yang telah copot. Ada banyak manfaat implan bila dibandingkan dengan prostetik macem lain, antara lain:Tulang yang tersisa jadi terpeliharaKebersihan mulut lebih mudah dijagaLebih awetGigi di sisi kanan dan kiri tidak diotak-atikDalam rangka untuk memperoleh hasil perawatan implan gigi yang estetis dan ...

Implan gigi sebagai solusi final

Apabila gigi depan pasien sudah copot dan ingin diganti dengan gigi palsu, dokter gigi dan pasien perlu bersama-sama mengambil keputusan tentang metode peggantian gigi tersebut. Pilihan umum yang tersedia meliputi:Gigi palsu parsial cekat konvensionalKelebihan gigi palsu parsial cekat meliputi setidaknya 3 prakara berikut ini:Prosedur perawatan mapanHasil estetika mudah diprediksiSolusi praktis d...

Pertimbangan penanaman implant gigi multipel (3)

(Lanjutan) Membuat ulang papilla interdental di antara dua implant yang berdekatan itu tugas yang tidak mudah. Dari sisi restoratif, dokter mengubah posisi poin kontak untuk menciptakan ilusi papilla. Spikula tulang tipis yang ada di antara implant bisa cukup untuk mempertahankan papilla selama beberapa tahun pertama setelah layanan perawatan restorasi. Namun, sampai kala ini belum pernah ad...

Pertimbangan penanaman implant gigi multipel (2)

(Lanjutan) Apabila implant dipasang 3 mm atau lebih, penyusutan tulang lateral dari implant di dekatnya tidak bertumpang tindih dengan minimnya penyusutan tulang kresta. Karena itu bisa disimpulkan, membuat atau memelihara papilla di antara dua implant yang berdekatan itu lebih sulit daripada membuat atau memelihara papilla di antara gigi natural dan implan. Apabila ada dua implant yang dipasang s...

Pertimbangan penanaman implant gigi multipel (1)

Pasien dengan ruang ompong tahap lanjut punya tingkat kesulitan anatomis dan estetis yang lebih tinggi. Akibatnya, pasien tersebut akan lebih sulit untuk memperoleh kepastian hasil estetis.Setelah 2 gigi yang berdekatan dicabut dan luka bekas cabutan sembuh, selanjutnya resorpsi pada arah apikal dan fasio-lingual menghasilkan segmen ompong yang datar. Pertimbangan diagnostik yang sama perlu dipi...

Penempatan implant pada arah fasio-lingual

Lebar tulang kresta perlu diperiksa untuk mengetahui ada-tidaknya atropi tulang. Penempatan implant berbeda-beda bergantung pada mekanisme retensi restorasi final (implan yang ditahan dengan sekrup dan implant yang ditahan dengan semen). Defisiensi lebar kresta alveolar ada kemungkinan memerlukan augmentasi agar implant bisa diposisikan pada arah fasio-lingual. Dalam kasus implant yang dipasang p...

Penempatan implant pada arah mesio-distal

Penempatan posisi implant pada arah mesiodistal yang kurang pas bisa pula menimbulkan efek besar pada pembentukan dukungan papilla interproksimal serta pada tulang kresta pada gigi-gigi di sekitar implant itu.Implan hendaknya dipasang pada jarak antara 1,5 mm sampai 2 mm dari gigi sebelahnya. Terlalu dekat dengan gigi sebelah bisa menyebabkan resorpsi tulang kresta alveolar interproksimal. Dampa...

Penempatan implant pada arah apiko-koronal (2)

(Lanjutan) Ada juga situasi di mana ada kelebihan ketinggian jaringan dan prakara ini memerlukan perhatian juga. Pada macem pasien ini, prosedur scallop tulang diperlukan agar baru implant bisa ditempatkan pada posisi subgingiva. Cara yang paling efisien untuk memeriksa prakara ini adalah dengan menggunakan surgical guide (pemandu bedah) yang menegaskan margin gingiva.Kesalahan sedikit saja pada...

Penempatan implant pada arah apiko-koronal (1)

Aspek yang paling kritis dari penanaman implan gigi adalah posisi apiko-koronal. Kekurangan jaringan dalam dimensi ini bisa dihasilkan dari beberapa faktor. Tipe jaringan ini perlu ditangani secara khusus selama perencanaan perawatan. Karena grafting jaringan lunak dan jaringan keras itu rumit, maka pasien-pasien yang memerlukan prosedur ini dimasukkan dalam grup berisiko tinggi.Penyusutan tula...

Posisi implant

Pemasangan implant estetis didorong oleh filosofil restoratif dan biologis. Secara estetis, implant hendaknya dipasang untuk memenuhi paramter-parameter kontur agar restorasi memuaskan pasien dan dokter. Secara biologis, implant hendaknya dipasang agar memungkinkan pemeliharaan arsitektur jaringan lunak dan jaringan keras. Jika gigi yang ingin diganti belum copot, ada beberapa prakara yang perlu...

Struktur anatomi penentu pasca implant

Ada dua struktur anatomi yang penting dan yang menentukan prediktabilitas jaringan lunak setelah penanaman implant gigi. Struktur yang pertama adalah ketinggian dan ketebalan dinding tulang fasial dan struktur yang kedua adalah ketinggian tulang kresta alveolar pada daerah interproksimal.Ketinggian dan ketebalan dinding tulang fasialPrediktor penting untuk mengetahui level gingiva adalah posisi ...

Anatomi tulang daerah implant

Untuk bisa memperoleh kesuksesan restorasi implan gigi yang estetis, tulang di mana implant dipasang harus punya tiga konfigurasi dimensi yang memungkinkan penanaman implant dalam posisi restoratif yang ideal.Kadang dokter bertemu dengan pasien yang anatomi tulangnya tidak memadai untuk diberi perawatan implan. Dalam situasi semacam ini, dokter perlu menjelaskan kepada pasien bahwa pasien bukan h...

Posisi akar gigi di sebelah lokasi implant

Salah satu bagian dari pekerjaan mendiagnosis pasien yang membutuhkan implan gigi adalah radiografi peri-apikal. Hal ini perlu dilakukan karena posisi akar dari gigi kiri dan kanan lokasi kerapkali menghalangi penanaman implan gigi. Banyak di antara para pasien ini bisa memperoleh keuntungan dari ortodontik untuk memposisikan ulang gigi malposisi. Posisi akar gigi yang miring menghalangi penanam...

Merencanakan perawatan implant di daerah estetis (...

LanjutanBranemark et al. telah menguraikan tentang teknik-teknik bedah untuk menanam implant silindir yang bentuknya seperti akar gigi. Teknik Branemark telah terbukti selama puluhan tahun sebagai teknik yang dapat diprediksi untuk menanam gigi palsu ke dalam tulang rahang. Pada masa sekarang, dokter bisa meresepkan penanaman implan gigi dengan pengetahuan yang memadai dan dengan rasa percaya d...

Merencanakan perawatan implant di daerah estetis (...

Kesuksesan untuk mendapatkan pemasangan implant yang estetis bergantung pada seberapa banyak jaringan yang telah hilang sebelum implan dipasang. Semakin banyak tulang dan jaringan lunak yang hilang sebelum implant dipasangn, maka semakin tinggi tingkat kesulitan yang dihadapi dokter gigi untuk mencapai hasil estetis yang diharapkan oleh pasien dan dokter. Menanam implant tunggal punya kemungkin...

Sitokin mempercepat penyembuhan pasca implant

Autograft adalah solusi emas standar pada masa kini untuk memperbaiki kerusakan tulang dengan ukuran yang kritis. Namun ada kendala yang sulit diatasi dari autograf, yaitu keterbatasan ketersediaan jaringan donor yang cocok. Kendala ini menyebabkan penggunaan autograft jadi terbatas. Masalah lainnya, autograft perlu bedah kedua untuk mengambil jaringan graft. Bedah kedua ini punya potensi untuk ...

Tes biokompatibilitas materi implant

Tes biokompatibilitas implant pada pokoknya mengikuti standar ISO 10993 dan FDA. ISO 10993 sudah diperbarui berkali-kali. Yang paling baru kala ini adalah 10993:55. Implan yang mengikuti ISO 10993 dan lolos FDA punya biokompatibilitas yang tinggi dan relatif lebih aman ditanamkan dalam tubuh manusia.ISO 10993 ISO singkatan dari The International Organization for Standardization (Organisasi St...

Penentu sukses oseointegrasi implant gigi (3)

Lanjutan 10. Karakteristik permukaan implanKualitas permukaan menentukan reaksi jaringan terhadap implan. Ada tiga kategori properti permukaan implan:Properti mekanisProperti mekanis permukaan implant berkaitan dengan potensi tekanan pada permukaan yang bisa menghasilkan peningkatan kecepatan korosi dan aus yang berhubungan dengan tingkat kekerasan materi implan. Aus berkaitan dengan kekuatan mat...

Penentu sukses oseointegrasi implant gigi (2)

Lanjutan 6. Teknik bedahKerusakan minimal pada jaringan pada kala bedah adalah prakara yang penting untuk oseointegrasi. Hal ini dipengaruhi oleh kecepatan pengeboran dan pendinginan. Jika penerapan teknik bedah terlalu kasar, maka panas akibat gesekan akan menyebabkan peningkatan suhu di daerah operasi. Jika sudah mencapai suhu 47 °C selama 1 menit, maka jaringan tulang akan mengalami ne...

Penyembuhan luka bedah di sekitar implant gigi

Akar buatan ditanam ke dalam tulang rahang sekali untuk seterusnya untuk menopang gigi palsu. Penanaman ini menggunakan bedah. Gusi dibuka, tulang dibor, akar buatan ditanamkan ke dalamnya, dan kemudian luka bedah ditutup kembali. Selanjutnya, dokter dan pasien sama-sama menunggu, berdoa, dan berharap agar implan jadi. Banyak pemasangan implan gigi yang sukses. Berita kesuksesan menyebar sehingga...

Kenali infeksi implant sedini mungkin

Implan copot adalah tahap lanjut dari infeksi pada jaringan di sekitar implan. Implan bisa dicegah agar tidak copot. Caranya, kenali infeksi sedini mungkin. Infeksi yang berhubungan dengan implant bisa terjadi pada 3 poin waktu, yaitu:0- 2 minggu setelah operasi implant gigiInfeksi pada titik waktu ini bisa terjadi karena operasi kurang steril. Sehingga, bakteri, virus, dan debris masuk ke dala...

Pelindung gigi pasca implant apakah perlu?

Apakah Anda perlu pelindung gigi (mouthguard) atau tidak itu bergantung pada kondisi dan kebiasaan Anda. Pasien implant yang memerlukan pelindung gigi adalah pasien implan dengan ciri sebagai berikut:Bruxism (kerot)Kerot menyebabkan gigi implant bergesekan dengan gigi oposisi. Arah gesekan ke samping, sedangkan implant itu lemah terhadap gaya dari samping. Jika ini berlangsung terus-menerus da...

Kenapa ada perawatan implant murah dan mahal?

Karena ada perbedaan komponen perawatan implant antara satu dengan yang lain. Ibaratnya, harga mobil Formula 1 berbeda dari harga mobil odong-odong karena beda komponen. Seperti yang kita ketahui, harga pasaran perawatan implant punya rentang yang lebar antara Rp 7 juta hingga Rp 50 juta. Faktanya, sekalipun ada perawatan implant harga Rp 7 juta, perawatan implant harga Rp 50 juta tetap ada pasie...

Fondasi implant gigi

Sederhananya, perawatan implan gigi itu menanamkan gigi palsu ke tulang rahang di bawah gusi. Artinya, Anda perlu tulang rahang dengan ukuran dan kepadatan yang cukup agar bisa ditanami gigi palsu. Tulang yang terlalu tipis atau yang kurang padat tidak cukup untuk menanamkan akar gigi palsu itu. Singkatnya, fondasi dari implan adalah tulang.Apakah tulang Anda cukup?Ini pertanyaan yang perlu dij...

Apa beda implant gigi dan tanam gigi?

Anda mungkin pernah mendengar kata "implan gigi" kala mengikuti seminar atau kala berkonsultasi dengan dokter gigi. Pada kesempatan lain, Anda bertemu dengan marketer yang menawarkan layanan tanam gigi. Pernakah Anda bertanya-tanya apa sebetulnya perbedaan antara implan gigi dan tanam gigi?Tidak ada perbedaan berarti antara implan gigi dan tanam gigi. Keduanya sama-sama diterjemahkan dari kata b...

Mikroba dan implant gigi

Implan berada dalam keadaan steril sebelum kemasan implant dibuka. Kemasan yang rusak menandakan kontaminasi pada implan. Sebelum membuka kemasan implan, pastikan dulu kemasan tertutup rapat sempurna. Setelah kemasan dibuka, implant terpapar berbagai mikroorganisme dari udara terbuka. Oleh sebab itu, sebelum implant dibuka, siapkan wadah berisi antibiotik untuk merendam implan, Kemasan implan...

FGF-2 dalam perawatan implant

Stabilitas implan merupakan syarat dasar untuk kesuksesan implant gigi. Stabilitas implant terdiri dari stabilitas primer dan stabilitas sekunder. Stabilitas primer terutama berasal dari penguncian mekanis antara permukaan implant dan tulang kortikal yang ada di sekitar implan. Stabilitas sekunder bukan hanya berasal dari koneksi struktural, tapi juga koneksi fungsional antara tulang dan implant y...

Peran osteoblas dalam implant gigi

Peran osteoblast tidak dapat diabaikan dalam perawatan implant gigi. Tanpa osteoblas, implant yang ditanam tidak akan berpadu dengan tulang karena osteoblas bertanggung jawab atas pembentukan tulang. Pembentukan tulang dipengaruhi oleh massa osteoblas. Penurunan massa osteoblas bisa dihasilkan dari defisiensi diferensiasi osteoblas, penurunan proliferasi, dan peningkatan kematian sel. Osteo...

Peran darah untuk kesuksesan implant gigi

Para pakar implant telah melakukan penelitian mekanis dan histologis berkenaan dengan respon tulang terhadap trauma. Mereka sangat berminat mengamati proses biologi molekuler yang berlangsung dalam perawatan implan. Termasuk dalam minat mereka ini adalah peran penting darah dalam menentukan kesuksesan implant gigi.Respon tubuh pasien implant dipengaruhi oleh kehadiran implan, karakteristik, stabi...

Reoseointegrasi untuk menangani implant gagal

Implan gigi yang mengalami kegagalan purwa atau pun kegagalan purna menunjukkan fenomena penyusutan tulang (bone loss). Apabila kondisi ini dibiarkan, maka penyusutan tulang terus berlanjut sampai tulang penyangga implant betul-betul tak tersisa. Akibatnya, implant copot dan implant baru tidak bisa dipasang di tempat itu karena tulang untuk menaruh implant sudah tidak ada lagi. Maka, tujuan sederh...

Stabilitas prostetik-implant: sekrup atau semen

Perkembangan teknologi implan gigi telah berhasil meningkatkan stabilitas biomekanis antarmuka abutmen-implan. Hal ini, pada gilirannya, sangat meningkatkan stabilitas mekanis restorasi. Juga, prakara ini pada umumnya meningkatkan respon dari jaringan lunak dan jaringan keras di sekitar implant terhadap implan. Stabilitas biomekanis implant dipengaruhi oleh sejumlah hal, antara lain: koefisien fri...

Hepatitis C & implant gigi

Tanya Saya sakit hepatitis C dan ingin memasang implant gigi. Apakah bisa? Saya dengar-dengar katanya bisa. Bagaimana yang sebenarnya? Jawab Implan gigi bisa dipasang pada pasien hepatitis C meskipun kasus ini tergolong kasus yang rumit. Jawaban singkatnya, bisa tapi lebih rumit dan lebih berisiko bagi Anda. Karena tingkat kerumitannya dan risikonya, Anda disarankan untuk hanya ditangani oleh...

Tips meredakan pendarahan pasca-operasi implant

Operasi pemasangan implant memerlukan irisan pada gusi. Irisan ini normalnya mengeluarkan darah dalam jumlah yang tidak terlalu banyak. Jika pasien dalam keadaan saras tanpa menderita penyakit, misal diabetes mellitus, darah yang keluar wajarnya tidak banyak dan jumlah itu akan semakin berkurang irisan ditutup kembali dengan penjahitan. Darah yang tidak berhenti keluar 24 jam hingga 48 jam setel...

Kelemahan implant gigi

Pasien perlu informasi yang benar dan lengkap mengenai perawatan implan, baik itu informasi yang menunjukkan kekuatan implan maupun kelemahan implan. Sebagaimana semua prakara di jagat ini yang punya kekuatan dan kelemahan, implant juga punya kekuatan dan kelemahan. Kekuatan implant ada banyak sekali, sedangkan kelemahannya ada sedikit, sebagaimana yang akan kita bahas di bawah ini.Dengan memberi...

Pemeliharaan implant gigi

Setiap 6 bulan sekali, pasien disarankan untuk kontrol ke dokter gigi implan. Selain dalam rangka untuk deteksi dini dan memastikan keamanan implan, kontrol 6 bulan sekali juga berguna untuk pemeliharaan implan. Hal ini meliputi instrumentasi dan debridema implan. Ada beberapa tahap yang diperlukan untuk melakukan pemeliharaan implan.Tahap pemeliharaan implan1. Pemeriksaan radiografiPasien datang ...

Implan gigi dalam peradaban kuno

Selama ribuan tahun yang lalu, manusia sudah punya gigi. Implikasinya, perkara gigi pada manusia juga sudah berlangsung selama ribuan tahun. Ide implant kuno tidak  dapat dilepaskan dari fenomena masalah yang terjadi pada gigi. Gigi yang tanggal mendorong para dukun, yaitu dokter ala peradaban kuno, untuk berpikir keras bagaimana cara mengganti gigi ompong.Dukun-dukun dalam peradaban kuno me...

5 Ramalan dunia implant gigi masa datang

Perkembangan ilmu pengetahuan dan teknologi implant dan implan gigi berlangsung sangat cepat, terutama semenjak dasawarsa 1980an ketika implan gigi modern pertama terbukti sukses dan mampu bertahan berfungsi selama 20 tahun. Berbagai kreasi dan inovasi di bidang implantologi gigi pun bermunculan. Hasilnya, hanya dalam waktu 3 dasawarsa, implan dengan kecanggihan teknologi yang menopangnya menjadi...

Pemandu bedah implant gigi

Pemandu implant atau implant guide (biasa disebut "guide") adalah piranti yang dipakai oleh dokter gigi implant untuk memandu agar implan punya posisi dan sudut dengan akurasi yang lebih tinggi daripada bila tanpa menggunakan piranti ini. Dokter dengan jam terbang operasi yang tinggi terkadang ada yang hanya menggunakan guide mental dalam bayangan di kepalanya. Entah yang berupa fisik atau yang s...

Perawatan saluran akar atau implant gigi?

Suatu penelitian oleh Hannahan et al. mengevaluasi tingkat kesuksesan gigi yang dirawat dengan perawatan saluran akar (perawatan endodontik) atau gigi yang dicabut lalu diganti dengan implan. Penelitian tersebut dilakukan pada 129 implant selama rata-rata 36 bulan dan 143 gigi yang dirawat endodontik selama rata-rata 22 bulan. Hasil penelitian menunjukkan bahwa tingkat kesuksesan di antara ked...

Apa implant titanium sekuat dalam film X-men?

Tanya Apa implant titanium sekuat dalam film X-men? Implan titanium di tangan karakter Wolverine dalam film X-men Jawab Titanium lebih keras daripada baja tapi lebih ringan daripada aluminium. Penggunaannya sebagai senjata telah dikenal sejam jaman dulu kala. Menurut cerita tradisional yang diwariskan turun-temurun dalam kawula Jawa, ada tombak dan keris yang dibuat dari titanium ya...

Makanan - minuman panas & implant titanium

Tanya Saya baru saja memasang implant titanium. Baru saja saya membaca tulisan kalau panas mematikan sel tulang penopang implan. Saya jadi bertanya-tanya, apa saya boleh makan atau minum yang panas-panas? Minuman kesukaan saya kopi panas dan makanan favorit saya bakso. Keduanya nikmat sekali kalau dinikmati kala masih panas. Jadi bagaimana ya? Jawab Penelitian yang dilakukan oleh Eriksson & A...

Cara melepas implant gigi

Ada beberapa kondisi yang membuat beberapa orang pasien jadi punya alasan melepas implan, misalnya menganut kepercayaan baru yang melarang pemakaian implan. Apabila prakara ini terjadi, maka dokter bisa mengabulkan keinginan pasien untuk melepaskan implan bila pasien menghendakinya demikian setelah mendengarkan dan mempertimbangkan pertimbangan medis dari dokter. Implan terpasang kokoh pada tu...

7 Alasan melepas implant gigi

Setelah implant terpasang, ada setidaknya 7 alasan bagi pasien untuk melepas implan, yaitu: Oseointegrasi gagalPada purna masa penyembuhan, sekitar 4 bulan setelah operasi pemasangan implan, dokter memeriksa apakah implan jadi. Jika tidak, maka dokter akan melepas implant tersebut dan menawarkan pengulangan prosedur atau opsi alternatif.Alergi logam atau keracunan titaniumAda pasien-pasien tert...

Panas bisa menggagalkan implant gigi

Panas tinggi yang timbul dari tindakan mengebor tulang (osteotomi) menyebabkan kematian sel-sel tulang. Akibatnya, jaringan tulang tidak merespon implant dan kondisi ini pasti menghasilkan kegagalan implan. Panas setinggi 47 °C atau lebih bisa menghasilkan kematian sel-sel tulang atau osteonekrosis (Eriksson & Albrektsson, 1983). Artinya, kesuksesan atau kegagalan implant ditentukan oleh kema...

7 Alasan tak perlu cemas dengan implant gigi

Sekurang-kurangnya ada 7 alasan kenapa Anda tidak perlu cemas dengan operasi pemasangan implant gigi. Mau tahu apa 7 alasan tersebut? Simak uraian berikut ini.7 Alasan Yang Perlu Anda Tahu1. Aman dan tidak mematikanImplan gigi modern mulai diterapkan pada manusia pada tahun 1965. Sejak tahun tersebut sampai sekarang, operasi implan gigi tidak pernah satu kalipun menyebabkan pasien meninggal dunia...

Detektor logam bandara & implant gigi

Tanya Apakah detektor logam di pos pengamanan bandara, mall, dsj bisa mendeteksi implant gigi? Apakah implant membunyikan alarm detektor logam? Jawab Tergantung sensitivitas piranti tersebut dan setelannya. Terkadang alarm menyala dan terkadang tidak. Sampai sekarang, pasien implant kami tidak mengalami perkara di pos pemeriksaan bandar udara.Cara kerja detektor logamUmumnya detektor log...

Permintaan implant gigi

Persistence Market Research mempublikasikan Laporan Pasar Baru dengan judul "Penelitian Pasar Global tentang Implan Gigi - Asia Pacific Menyaksikan Pertumbuhan Tercepat pada 2020". Pasar implan gigi global diperkirakan akan bernilai USD 7.879,5 juta in 2020 dengan CAGR 9,7% dari 2014 sampai 2020. CAGR atau Compound Annual Growth Rate adalah tingkat pertumbuhan tahunan rata-rata suatu inves...

7 Poin perlu diketahui sebelum implant gigi

1. Ada syarat selain ompongCalon pasien yang datang ke klinik terkadang ada yang mengira semua kondisi ompong bisa dirawat dengan implant gigi. Kenyataannya, ada syarat selain ompong yang perlu terpenuhi untuk menerima implan. Misal, kepadatan, lebar dan tinggi tulang cukup untuk menopang implan. Tentang syarat, indikasi, dan kontraindikasi implant sudah dibahas sebelumnya. Silakan disimak.2. Kes...

Apa semua orang yang ompong bisa dirawat implant?

Tanya Apa semua orang yang ompong bisa dirawat implan? Jawab Implan gigi memang terutama ditujukan pada pasien penderita ompong (edentula). Motif penciptaan implant adalah mengganti gigi yang tanggal dengan gigi implan. Tapi, pada kenyataanya, tidak semua penderita ompong bisa dirawat dengan implan gigi karena dokter mesti mempertimbangkan indikasi dan kontraindikasi perawatan implan.Pada kedat...

Perlakuan permukaan implant gigi

Perlakuan permukaan implan dimaksudkan untuk membentuk permukaan gigi agar jadi lebih kasar. Kekasaran permukaan implan berperan penting dalam memengaruhi nilai kontak tulang-implan (BIC) yang lebih tinggi. Nilai BIC yang tinggi menentukan kesuksesan oseointegrasi dan implan. Jadi, perlakuan permukaan implan mengambil bagian penting dalam meningkatkan peluang kesuksesan implan.Macam perlakuan p...

Terapi HBO dan implant gigi

Terapi HBO (Hyperbaric oxygen) adalah modalitas perawatan dimana pasien menghirup oksigen 100% sementara diberi paparan tekanan atmosfer yang semakin meningkat dan terkontrol. Terapi ini bisa meningkatkan proses penyembuhan natural tubuh manusia. Dengan terapi ini, oksigen yang normalnya hanya dihantarkan oleh darah juga dihantarkan oleh fluida sistem saraf sentral, limpa, fluida tubuh lannya, dan...

Kekasaran permukaan implant gigi

Kekasaran permukaan implan berperan penting dalam memperkokoh dan menyuksesan penjangkaran implant pada tulang. Kenapa?Respon jaringan terhadap implant sangat dipengaruhi oleh watak dan tekstur permukaan implan. Permukaan bertekstur mempunyai area yang lebih luas ketimbang permukaan rata. Permukaan yang lebih luas ini membuat area untuk berlangsungnya oseointegrasi jadi lebih luas. Permukaan impla...

Robot implant gigi masa datang

Salah satu faktor yang memengaruhi hasil dari operasi implan gigi adalah akurasi, termasuk akurasi anatomi, akurasi pengeboran tulang rahang, dan akurasi pemasangan implant ke dalam lubang tersebut. Robot implan diharapkan memberi tingkat akurasi presisi dan stabilitas yang lebih daripada manusia serta mempermudah dan mempercepat pekerjaan pemasangan implan.Alon Mozes dan Juan Salcedo mulai pene...

Pasien bisa mendeteksi dini masalah implant

Pasien bisa mendeteksi dini perkara implant yang dipakainya asalkan mau belajar tentang ciri-ciri dini perkara implan. Deteksi dini dan kecurigaan membantu pasien untuk mencegah komplikasi pada jaringan lunak dan keras penopang implan. Begitu kecurigaan muncul, jangan tunggu-tunggu, langsung saja hubungi dokter gigi implant kami. Jangan berharap perkara implant bisa diatasinya sendiri atau berh...

Permukaan implant gigi

Kesuksesan implan gigi bergantung pada kesuksesan oseointegrasi dan kesuksesan oseointegrasi bergantung pada kontak tulang-implan. Kesuksesan kontak tulang-implan (BIC) dipengaruhi oleh permukaan implan. Artinya, permukaan implant punya peran yang menentukan kesuksesan atau kegagalan implan. Perlakuan pada permukaan implanAcid-etched (Etsa asam)Etsa menggunakan asam kuat menghasilkan peningkata...

Kontak Implan-Tulang

DefinisiKontak implan-tulang atau bone-implant contact (BIC) adalah persentase tulang yang langsung kontak dengan permukaan implant (Locca, 2016). Persentase kontak implan-tulang bisa memengaruhi jumlah stres/ regangan pada antarmuka. Menurut Misch (2008), kepadatan tulang memengaruhi jumlah tulang yang kontak dengan permukaan implan. Hal ini bukan hanya terjadi pada bedah tahap pertama, tapi jug...

Tingkat kesuksesan implant 20 tahun setelah pemasa...

Bukan cuma pasien, dokter dan peneliti juga ingin tahu bagaimana tingkat kesuksesan dan tingkat sintasan implan gigi setelah 20 tahun. Sekalipun produsen implant mengklaim prakara yang serba positif, tapi kita toh tidak dapat percaya begitu saja pada klaim produsen. Sehingga, penelitian-penelitian ilmiah tentang implant pun berkembang mengenai topik ini.Penelitian Chappuis et al. (2013) adalah pen...

Bagaimana cara mengantisipasi risiko implant gigi?

Tanya Bagaimana cara mengantisipasi risiko implant gigi? Jawab Hidup kita sehari-hari yang selalu mengandung risiko, seperti risiko jatuh kala jalan kaki, risiko kecelakaan kala menyetir kendaraan, dsb. Begitu pula, perawatan implan gigi mengandung risiko. Risiko dalam hidup keseharian kita bisa diantisipasi, begitu pula risiko implan gigi juga bisa diantisipasi.Ada beberapa cara mengantisipasi...

Malpraktik implant, mungkinkah terjadi?

Penelitian ilmiah telah mengeksplorasi jenis-jenis tuntutan hukum yang berkaitan dengan malpraktik di AS. Sebelum tahun 2005, Charles Sloin, pakar di bidang manajemen risiko gigi melakukan penelitian yang tak dipublikasikan pada lebih dari 1.200 klaim makpraktik gigi yang telah terselesaikan antara tanggal 1 Januari 1987 sampai 31 Desember 1995. Selanjutnya, pada tahun 2005, Asosiasi Gigi Amerika ...

Rekam medik implant gigi

Babbush et al. (2011) menyarankan rekam medik untuk pasien implan gigi hendaknya meliputi hal-hal berikut ini:1. Diskusi yang bermaknaDiskusi yang bermakna meliputi:Temuan obyektif dokter gigiKeluhan subyektif pasien terkait perawatan implanTemuan abnormalHasil tesTemuan positif yang penting bagi diagnosis implanSemua temuan yang penting untuk pengembangan rencana perawatanTemuan negatif atau temu...

Radiografi untuk implant gigi

Pemeriksaan radiografi, seperti misal foto rontgen, jadi bagian penting dalam perawatan implan gigi mulai dari tahap perencanaan hingga evaluasi perawatan jangka panjang untuk meningkatkan peluang sukses perawatan implan. Radiografi juga berguna untuk memastikan implant yang gagal, bukan hanya implant yang berhasil saja.Radiografi standar untuk gigi memungkinkan klinisi melakukan penilaian purwa ...

Alternatif untuk implant gigi

Alternatif untuk implan gigi itu ada, yaitu teknologi-teknologi yang sudah ada sebelum implant modern mengemuka. Teknologi alternatif bagi implant itu biasanya tidak senyaman atau tidak lebih baik ketimbang implan. Walau begitu, bila Anda tidak dapat menerima perawatan implan, maka teknologi tersebut masih diperlukan.Alternatif bagi implanBerikut ini adalah alternatif bagi implan. Alternatif-alter...

Gerakan implant gigi

Fiksasi tegar menandakan ketiadaan gerakan implan. Hal ini bisa diuji menggunakan daya vertikal dan daya horisontal kurang dari 500 gram.Dukungan abutmen implant paling dapat diprediksi dengan fiksasi tegar. Ketiadaan atau kekurangan mobilitas implant tidak selalu identik dengan kontak langsung antarmuka tulang-implan. Namun, fiksasi tegar biasanya berarti sekurang-kurangnya sebagian dari permuk...

4 Musuh Implan Gigi

Musuh implant gigi menyebabkan implant kalah dan akhirnya copot dari tempatnya. Pasien perlu mengenali musuh implan agar dapat membuat keputusan yang bijak tentang apa yang perlu dilakukannya.1. Gigitan yang terlalu kuat.Implan tidak punya saraf. Ini menyebabkan pasien tidak dapat merasakan apakah kekuatan gigit yang diberikannya terlalu besar atau tidak. Karena tidak dapat merasakan, akhirnya pas...

Apa pentingnya stabilitas implant?

Nilai penting stabilitas implanStabilitas implan memegang peranan yang sangat penting dalam menentukan kesuksesan atau kegagalan implant gigi. Implan yang tidak stabil ditandai dengan gerakan implan. Implan yang bergerak menyebabkan infeksi pada jaringan di sekitar implan. Infeksi mengundang reaksi dari sistem kekebalan tubuh pasien dengan hasil purna berupa kapsul fibrosa dan menyebabkan proses ...

Andai implant gagal, apa yang akan terjadi?

Tanya Bagaimana jika implant gagal? Apa yang akan terjadi? Jawab Prosedur implan gigi jarang gagal. Tingkat kegagalan implan hanya 1,4% hingga 4,93%, singkatnya, kurang dari 10%. Pertanyaan Anda menyiratkan pertanyaan "Bagaimana jika yang 1,4% itu terjadi pada saya?" Baiklah, mari kita bahas, bagaimana jika yangn 1,4% tersebut terjadi pada Anda.Apabila implant menunjukkan gejala dini yang meng...

7 Fakta menarik tentang implant gigi

Berikut fakta-fakta menarik mengenai implan gigi.Teknologi maju dari peradaban kunoImplan gigi pertama kali digagas dan dipraktikan oleh peradaban bangsa Maya pada abad 6 Masehi. Dukun bangsa Maya menggunakan bahan baku kerang untuk membuat gigi implant dan menanamkannya ke dalam tulang rahang. Hasilnya, tulang rahang berpadu dengan implant dari bahan kerang itu. Sumbangsih peradaban bangsa M...

Jika implant gigi gagal, apa tetap bayar?

Tanya Jika implan gigi gagal, apakah saya tetap harus bayar? Kan saya tidak dapat apa-apa. Harusnya ga bayar dong. Jawab Perlu kita sadari bersama, setelah implant dengan kualitas memadai dipilih dan dokter gigi implant mengikuti prosedur implan gigi dan mengerahkan teknik terbaiknya untuk memasang implant tersebut, maka implan gigi gagal atau sukses bergantung pada respon tubuh pasien pada...

Implan gigi pada masa hamil

Tanya Apakah saya bisa pasang implan gigi kala sedang hamil? Jawab Kehamilan bukan kontraindikasi mutlak pemasangan implant gigi. Walau begitu, kami menyarankan untuk menunda pemasangan implant setelah bayi Anda lahir. Alasan kami adalah sebagai berikut:Bedah/ operasiPemasangan implan gigi memerlukan operasi, sedangkan ibu yang sedang hamil sebaiknya tidak menjalani pembedahan, termasuk pembe...

Implan gigi: Mitos vs Kenyataan

Internet berisi banyak sekali informasi mengenai implant gigi. Sayangnya, banyak di antara informasi itu hanya mitos. Ada banyak motif kenapa orang membuat mitos. Di sini kita tidak akan membahas motif pembuatan mitos. Yang kita bahas sekarang adalah mitos-mitos tentang implan gigi dan bagaimana kenyataan yang sebenarnya.Mitos 1: Implan gigi bikin mulut jadi bau.Kenyataannya, bau pada gigi impla...

Implan gigi harga murah Rp 3 - 5 juta. Betulkah ad...

Tanya Saya mendapat pariwara implan gigi harga murah Rp 3 juta. Iklan yang satunya lagi harga Rp 5 juta. Terus ada yang menawari Rp 7 juta. Kenapa harga di klinik doctor+dentist bisa pada kisaran 12 belas juta? Apa tidak bisa lebih murah lagi? Jawab  Ada tapi cuma pasak implant-nya saja. Belum termasuk abutment, crown, operasi, rontgen, perawatan, dsb. Kalau hanya pasak implant saja, bisa lih...

Garansi implant gigi

Tanya Apakah ada garansi untuk implan gigi yang dipasang di klinik doctor+dentist? Jawab Ada beberapa pertimbangan untuk menjawab pertanyaan Anda.Pertama, keawetan implan gigi ditentukan oleh pasien. Implan gigi bukan layanan pasang sekali dan untuk seterusnya. Daya tahan implant dipengaruhi oleh gaya hidup dan kebiasaan pasien. Misal, pasien yang merokok punya kemungkinan yang lebih tingg...

Skala kesehatan implant James - Misch

Skala kesarasan implan disarankan oleh James dan kemudian dikembangkan oleh Misch (2008). Karena itu, skala kesarasan implant ini selanjutnya dikenal dengan nama "Skala Kesarasan Implan James-Misch".Skala kesarasan implan tersebut membagi keadaan implant menjadi 4 grup sebagai berikut: Grup I Ciri: Tidak teramati ada rasa sakit dengan palpasi, perkusi, dan fungsi. Tidak terasa emp...

Stabilitas implant gigi

Stabilitas implan adalah indikasi oseointegrasi yang sifatnya tidak langsung. Jika implant tidak stabil, maka akan terjadi infeksi yang memicu reaksi penolakan tubuh terhadap implant dan proses oseointegrasi tidak akan terjadi. Dengan mengetahui stabilitas implan, maka oseointegrasi juga bisa diketahui. Stabilitas implant adalah ukuran imobilitas klinis implan. Begitu yang diusulkan oleh Cochran ...

Implan gigi vs terapi radiasi

Implan gigi yang telah sukses tertanam dan berpadu kokoh dengan tulang rahang sebaiknya jangan sampai terkena paparan sinar radiasi, misalnya radiasi dari terapi radiasi. Menurut penelitian yang dilakukan oleh Teramoto et al. (2016), sel-sel tulang yang terkena paparan sinar radiasi bisa mati karena terkena sinar radiasi tersebut. Hal ini diistilahkan osteoradionekrosis, artinya, kematian sel tu...

Osteoporosis dan implant gigi

Penyakit tulang yang paling umum ditemui oleh dokter gigi implant adalah osteoporosis. Penyakit yang berkaitan dengan umur ini dicirikan dengan penurunan massa tulang, kondisi arsitektur mikro yang semakin merosot, dan kerentanan terhadap fraktur. Kondisi umum terjadi pada perempuan pasca-menopaus. Perubahan-perubahan yang dikarnakan oleh osteoporotis pada rahang manusia serupa pada tulang-tula...

Implan nanotube temuan Dr. Cortino Sukotjo

Pengantar implant nanotubeImplan gigi bisa sangat membantu meningkatkan kualitas hidup manusia yang memerlukannya. Tapi ada 2 tantangan yang dihadapi oleh dokter gigi implan, yaitu: risiko infeksi dan, akibatnya, lepas dari tempatnya terpasang. Pertanyaannya, bagaimana cara untuk mengatasi 2 prakara ini?Infeksi dikarnakan oleh mikroorganisme, seperti bakteri, dalam mulut yang jumlahnya sangat bany...

Analisis frekuensi resonansi (RFA) & stabilitas im...

Analisis Frekuensi Resonansi atau Resonance frequency analysis (RFA) adalah metode yang dipakai untuk menentukan stabilitas dan tingkat oseointegrasi dalam implant (Bilbao et al. (2009) dan Veltri et al. (2009)). Stabilitas implan ditunjukan dengan nilai ISQ (Implant Stability Quotient). Semakin tinggi nilai ISQ, semakin tinggi pula stabilitas implan. Teknik ini diperlukan guna mengetahui stabili...

Penentu penjangkaran implant gigi

Berapa lama implan gigi dapat bertahan dan berfungsi dalam mulut pasien bergantung pada penjangkaran implan dalam tulang rahang, baik penjangkaran mekanis maupun penjangkaran bioaktif. Penjangkaran tersebut ditentukan oleh 6 faktor yang saling mendukung satu sama lain. Karena itu, semua faktor itu perlu ada. Faktor penjangkaran implanFaktor-faktor yang dimaksud meliputi:1. Biokompatibilitas imp...

Apa gigi implant bisa berlubang?

Tanya Apa gigi implant bisa berlubang? Jawab Tidak, gigi implant tidak bisa membusuk sehingga tidak bisa berlubang. Alasannya, mahkota yang dipasang di atas implant itu dibuat dari bahan-bahan yang tidak bisa dilubangi oleh kuman-kuman mulut. Bahan implant antara lain berupa titanium, zirkonia, stainless steel, dsb. Tentang bahan yang digunakan untuk membuat implant dan mahkota implant su...

Evaluasi kepuasan pasien implant gigi

Kepuasan pasien implant merupakan prakara yang sangat penting bagi kami, dokter gigi implan. Sampai-sampai, kepuasan subyektif pasien menjadi salah satu kriteria sukses implan. Cukup banyak penelitian yang mengevaluasi kesuksesan implan. Berikut akan kita bahas beberapa di antaranya.Penelitian Allen et al. (2001), Bakke, Holm, Gotfredsen (2002), dan Boerrigter et al. (2002) mengusulkan bahwa pasie...

Respon jaringan tulang pada implant gigi

Respon jaringan tulang pada implan gigi yang ada di dekatnya itu penting untuk kesuksesan implan. Jika jaringan tulang tidak merespon, maka implant akan gagal. Mari kita bahas.Osteogenesis jarakProses penyembuhan tulang secara bertahap ke arah dalam dari tepi osteotomi ke arah implan. Tulang tidak tumbuh langsung ke arah permukaan tulang.Pada osteogenesis jarak, osteosit pada tepian tulang yang d...

Obat depresi berkaitan dengan kegagalan implant

Penelitian terbaru di bidang implan gigi oleh Universitas McGill menemukan bahwa prosedur implant bisa menghasilkan kegagalan pada pasien yang mengkonsumsi obat-obatan anti-depresan, seperti Celexa, Paxil, Lexapro, Prozac, and Zoloft. Para peneliti dari universitas tersebut menyarankan, SSRI (Selective Serotonin Reuptake Inhibitors) dapat mengurangi pembentukan tulang. Ini bisa menyebabkan kompli...

MED - teknologi stimulator implant gigi

Biasanya, dokter gigi implant dan pasien menunggu waktu lebih kurang 4 bulan sampai tulang berpadu dengan implant dan cukup kokoh untuk menerima beban. Banyak peneliti berupaya mempercepat proses ini. Mereka pada umumnya mengotak-atik permukaan implan. Hasilnya, sejumlah penelitian memang bisa mempercepat proses ini tapi tidak signifikan.Perusahaan Magdent berinovasi untuk mempercepat proses denga...

Pemenang penghargaan EAO bidang implant gigi

Asosiasi Oseointegrasi Eropa atau The Europea Association for Osseointegration (EAO) mengumumkan pemenang penghargaan ilmiah di bidang ini. Penghargaan diberikan pada tanggal 1 Oktober 2016 dalam Kongres EAO tahunan oleh Björn Klinge, sekarang sudah jadi mantan presiden EAO digantikan oleh Alberto Sicilia.Pemenang penghargaanAdapun pemenang penghargaan tersebut adalah sebagai berikut:Penghargaan ...

Mekanisme oseointegrasi pada implant gigi

Mekanisme oseointegrasi pada implan gigi terdiri dari 4 fase sebagai berikut: 1. Fase hemostasisPada fase yang pertama ini, pendarahan yang timbul dari operasi pemasangan implant berhenti. Ketika pendarahan telah berhenti, kolagen yang terjadi secara natural akan menyembuhkan permukaan daerah implant dan menutup pembuluh darah yang pecah. Selanjutnya platelet akan memfasilitasi jaringan serat d...

Antisipasi faktor eksogen kegagalan implant awal

Faktor eksogen penyebab kegagalan implant awal ada 2, yaitu: faktor yang berkaitan dengan operator dan faktor yang berkaitan dengan biomaterial.1. Faktor kegagalan implant terkait operatorSejumlah penelitian implan gigi oleh Listgarten (1997), Morris, Manz, dan Tarolli (1997), Lambert, Morris, dan Ochi (1997), Preiskel dan Tsolka (1995), dan Truhlar, Morris, Ochi, dan Winkler (1994) menyarankan ...

Indeks estetika mahkota implant gigi

Carl E. Misch (2015) dalam bukunya "Prostetik Implan Gigi" menguraikan tentang indeks estetika mahkota implant sebagai piranti yang obyektif untuk menilai estetika mahkota tunggal yang didukung oleh implant dan jaringan lunak di sekitarnya. Estetika ini dapat dinilai dengan metode subyektif dan obyektif. Metode subyektif menggunakan kuisioner yang diselesaikan oleh pasien. Metode obyektif mengguna...

Kriteria sukses implant gigi

Kriteria sukses implan gigi didefinisikan oleh para pakar implan gigi sebagai berikut.1. Kriteria sukses Schnitman dan Schulman :Kriteria sukses implan gigi menurut Schnitman dan Schulman meliputi:Mobilitas kurang dari 1 mm ke arah mana punRadiolusens yang diamati dengan radiologi bergradasiPenyusutan atau penciutan tulang tidak lebih besar daripada sepertiga tinggi vertikal tulang.Inflamasi gi...

Benarkah implant zirkonia lebih baik daripada tita...

Menurut iklan, implant zirkonium diwartakan lebih baik daripada pariwara titanium. Tapi, apakah kenyataannya memang demikian? Apakah kenyataannya implant zirkonium memang lebih baik daripada implant titanium? Mari kita buktikan. Jumlah penelitianPenelitian tentang efektivitas implan titanium tersedia sangat banyak, jauh lebih banyak daripada implant zirkonia. Konsekuensinya, dokter gigi implant...

Implan gigi aman

TanyaApakah implan gigi aman?JawabImplan gigi dan prosedur pemasangan dan perawatannya sudah terbukti aman sejak pemasangan pertama tahun 1965 sampai tahun 2016 ini. Tingkat kesuksesan perawatan dapat dinaikkan sampai mencapai hingga 97% dan tingkat kegagalan juga bisa ditekan hingga kurang dari 10%. Untuk mencapai tingkat yang sangat bagus ini, perlu perencanaan yang baik dan pengalaman dokter...

Bahan implant gigi

Tanya Bahan implan gigi itu apa ya? JawabGigi implant terdiri dari bagian implan, abutment, dan mahkota.Mahkota (crown)Mahkota dibuat dari titanium, paduan logam titanium, zirkonium, atau keramik. Mahkota dari titanium murni punya watak yang paling keras dan paling kuat, tapi dari sisi estetika, mahkota titanium tidak menyerupai gigi asli, terkecuali diberi lapisan keramik yang dibuat mirip g...

Penyebab peri-implantitis

Peri-implantitis adalah penyakit yang tidak bisa pulih dengan sendirinya. Sekali merusak, maka bekas kerusakannya akan tetap ada. Karena itu, penyakit ini sebaiknya dicegah. Untuk bisa mencegah, Anda perlu tahu penyebabnya.Etiologi peri-implantitisEtiologi atau penyebab peri-implantitis antara lain sebagai berikut:InfeksiPlak yang dibentuk oleh bakteri atau produk turunannya  adalah penyebab infe...

Definisi peri-implantitis

Mengganti gigi ompong dengan gigi implant sudah jadi tren dalam kedokteran gigi modern di negara-negara maju. Prosedur peri-implantitis memberi hasil yang dapat diprediksi tapi sekaligus menimbulkan penyakit baru, yaitu: peri-implantitis. Dibandingkan implant yang sukses dan saras, pasien yang terkena penyakit ini relatif sedikit dan dapat ditangani dengan baik asalkan tidak terlambat. Karena itu...

Implan sistem Branemark

Bukti klinis tentang efektivitas oseointegrasi dalam sistem Branemark telah merevolusi ilmu kedokteran gigi implan. Bukti tersebut membuat implant sebagai pengganti gigi ompong jadi alternatif perawatan yang telah menuai banyak sukses untuk merawat berbagai kasus gigi ompong. Implan dengan penjangkaran yang melibatkan oseointegras menunjukkan hasil-hasil yang bisa direproduksi, tahan lama, bisa di...

Kegagalan implant gigi

Perawatan implan gigi adalah perawatan yang dianggap paling bagus dari sisi estetika dan fungsi bila dibandingkan dengan gigi palsu biasa. Tapi, perawatan ini tidak selalu sukses. Ada dua macem kegagalan dalam perawatan implan, yaitu kegagalan implan yang terjadi di purwa dan di akhir. Setiap macem kegagalan ini punya karakteristiknya masing-masing. Untuk meminimalkan kegagalan ini, kita perlu s...

Risiko implant gigi yang terlalu murah

Siapa pasien implant tidak mau implan gigi murah? Semua pasien dengan indikasi dan kontraindikasi yang sesuai mungkin akan senang mencobanya. Lebih lagi pasien yang telah berusaha keras namun mengalami kendala dalam upayanya memperoleh layanan implan gigi gratis. Tentang cara mendapat implant yang murah banget sudah pernah kita bahas. Kita pernah membahas implan gratis, murah banget, dan murah....

Efek kortikosteroid pada implant gigi

Tanya Apakah kortikosteroid punya efek pada implant gigi? Apa efek yang telah diketahui? Jawab Penelitian Fujimoto et al. (1998) dan Keller et al. (2004) menyarankan bahwa pemberian kortikosteroid memengaruhi oseointegrasi dan kontak tulang tapi pengaruh tersebut tidak kuat. Terbukti, kontak tulang pada kelompok penerima kortikosteroid dalam percobaan Keller et al. secara signifikan lebih s...

Tahap oseointegrasi pada implant gigi

Penentu implant jadi atau gagal adalah proses penyatuan atau integrasi tulang dengan implan. Proses ini dikenal dengan sebutan oseointegrasi (osseointegration) atau pemaduan tulang.Proses oseointegrasi terdiri dari beberapa tahap. Setiap tahap oseointegrasi ini perlu berjalan dengan baik agar implan jadi dan implant terpasang kokoh pada gigi.Tahap-tahap oseointegrasi meliputi:Tahap 1: kalus any...

Apa implant titanium bisa berkarat?

Tanya Apa implan titanium bisa berkarat??? Jawab Implan titanium sangat jarang sekali dan sangat ulit sekali berkarat, terutama implant titanium yang telah lolos uji kualifikasi FDA. Titanium menunjukkan watak resisten karat yang sangat baik bila dibandingkan dengan bahan-bahan implant logam lainnya. Walau begitu, titanium punya sangat kecil sekali kemungkinan untuk berinteraksi dengan jari...

Asam merusak implant gigi?

Tanya Apakah minuman dan makanan asam seperti es jeruk, jus lemon, dsj, merusak implant gigi? Jawab Tergantung pada nilai pH dalam makanan atau minuman asam itu dan kualitas implant yang Anda pakai.Implan titanium punya lapisan titanium dioksida (TiO2) di bagian luar implan. Lapisan ini memisahkan implant titanium dari udara luas. Sehingga, lapisan tersebut dapat berfungsi mencegah korosi terj...

Zirkonia: Implan bebas logam

Tanya Apa ada implant bebas logam? Jawab Ada implan bebas logam. Implan semacam ini dibuat dari keramik zirkonia sehingga bisa dipakai untuk perawatan implant pada pasien yang alergi logam.Teknologi implant Zirkonia masih sangat baru, baru ditemukan dan diperkenalkan ke kawula tahun 2005. Penelitian-penelitian mengenai implan ini masih dalam tahap yang sangat dini. Sebagian besar di antara pe...

Penjangkaran implant secara mekanik & bioaktif

Ada 2 macem penjangkaran implant pada tulang rahang, yaitu penjangkaran mekanik dan penjangkaran bioaktif.A. Penjangkaran implant secara mekanikPenjangkaran mekanik didasarkan pada kontak langsung antara tulang dan bentuk potongan logam pada implant di mana tulang mengkait implan. Bentuk potongan logam yang paling banyak dipakai adalah bentuk ulir seperti ulir sekrup, lubang-lubang di sisi implan,...

Segel biologis implant gigi

Sel-sel epitel dan jaringan ikat berperan penting membentuk segel biologis bagi implant gigi. Peran ini sangat penting sekali dalam kedokteran gigi implan.Kita tahu bahwa berbagai macem implan gigi pasti punya bagian mahkota atau super struktur yang didukung oleh pasak. Pasak ini pasti mealui submukosa (lamina propria) dan epitelium skuamosa agar bisa muncul dalam rongga mulut.Bagian permukosa ini...

Saran setelah implant gigi

Setelah implant gigi terpasang pada tulang rahang Anda, Anda perlu mengetahui apa saja yang perlu Anda lakukan dan jangan Anda lakukan. Gunanya, untuk menurunkan peluang kegagalan implan.Makanan lunakSetelah implant gigi dipasang pada lubang yang telah disiapkan, luka operasi dijahit. Jika terkena makanan keras, luka itu dapat terbuka dan berdarah lagi. Juga, implant dapat bergerak bila terkena m...

Cara dapat implant gigi murah banget

Anda mungkin telah mencoba cara dapat implan gigi gratis dan mungkin mengalami kesulitan dengan cara itu. Kenyataannya, apa-apa yang gratis itu memang tidak selalu mudah untuk mendapatkannya. Kalau begitu, coba cara dapat perawatan implan gigi murah banget ini. Siapa tahu Anda lebih sukses dengan cara ini. 1. Negara dengan biaya hidup lebih murah Klinik kami menangani sejumlah pasien dari negar...

Antibiotika sebelum implant gigi

Tanya Apakah pemberian antibiotik sebelum implan gigi dipasang mencegah kegagalan implan? JawabYang lebih tepat, pemberian antibiotika sebelum implan gigi dipasang bisa menurunkan peluang kegagalan implan. "Menurunkan peluang" lebih tepat dibandingkan "mencegah" karena bukti menunjukkan, implant masih punya kemungkinan gagal walaupun pasien telah menerima antibiotika sebelum operasi implan. ...

Anestesi lokal implant gigi

Anastesi lokal pertama kali digunakan di bidang kedokteran gigi oleh Dr. William Halsted pada tanggal 26 November 1884.Mekanisme Aksi Anestesi LokalAnestesi lokal memblokir rasa sakit dengan mengganggu pembentukan impuls penyebab rasa sakit di sepanjang serabut syaraf perifer. Hal ini dicapai dengan mengurangi permeabilitas membran sel syaraf terhadap ion-ion Natrium.Faktor Yang MemengaruhiAda be...

Implan gigi mini

Sesuai namanya, implant gigi mini berukuran mini, lebih kecil daripada ukuran implant standar. Lebar implant standar berukuran antara 3,4 sampai 5,8 mm, sedangkan lebar implant mini berukuran antara 1,8 sampai 3,3 mm. Panjang implant mini antara 10 sampai 15 mm.  Implant tradisional vs implant mini Mulanya dulu, implan gigi mini diperkenalkan sebagai piranti sem...

Perbaikan tulang di daerah implant

Kondisi Yang BerpengaruhPada pokoknya, tulang bisa bereaksi terhadap nekrosis dengan 3 cara yang berbeda, yaitu:Membentuk jaringan fibrosa.Tulang mati tetap sebagai sequester tanpa ada perbaikan.Penyembuhan dan pembentukan tulang baru atau oseointegrasi.Perbaikan tulang pada korteks implant nekrotik bergantung pada:Ketersediaan sel yang memadaiFaktor pertama yang berpengaruh langsung pada perbaik...

Proses oseointegrasi pada implant gigi

Proses integrasi atau penyatuan tulang dengan implant diistilahkan oseointegrasi. Pada proses ini, sel-sel tulang tumbuh menjalar ke arah implant dan melekat padanya. Setelah sel-sel tulang mengeras, maka tulang memegang implant dengan kokoh.Proses oseointegrasi tersebut teramati setelah implant disisipkan ke dalam lubang yang telah disiapkan. Proses ini dapat dibandingkan dengan proses penyembuha...

Berapa tingkat kegagalan implant gigi?

Tanya Berapa tingkat kegagalan implant gigi?Jawab: Tingkat kegagalan implan gigi dipengaruhi oleh banyak hal, antara lain:  kontraindikasi implanindikasi implan syarat pasang implandokter gigi implant berpengalamanpantangan implanprediktor kegagalan implan Bila hal-hal tersebut di atas diperhatikan, maka tingkat kegagalan implan dapat turun. Menurut Moy et al. (2005), tingkat k...

Cara dapat implant gigi gratis

Pemasangan dan perawatan implan gigi identik dengan harga yang kurang murah. Beraneka faktor menyebabkan harga implant sulit untuk ditekan. Walau begitu, ada cara untuk mendapat perawatan ini gratis. Mau tahu gimana caranya?Penyedia implan gigi gratisKeluarga.Jika Anda punya anak, cucu, keponakan, orangtua, bibi, paman, atau kerabat dekat lain yang jadi dokter gigi implan, Anda cukup beruntung....

Makan lunak setelah implant gigi

Tanya:Berapa lama masa makan makanan lunak setelah operasi pasang implant gigi?Jawab: Lama waktu Anda makan makanan lunak bergantung pada macem operasi pasang implant yang Anda jalani. Jika operasi Anda memendam implant dalam gusi, maka masa makan makanan lunak berlangsung antara 7-14 hari setelah implant gigi. Setelah itu, Anda bisa makan makanan normal. Hindari dulu makanan keras (daging). Bi...

Selisih waktu cabut gigi & implant gigi

Tanya:Berapa lama selisih waktu yang diperlukan antara cabut gigi dan pasang implant gigi? Bisakah implant dipasang langsung setelah gigi dicabut?Jawab:Implan bisa saja langsung dipasang di lubang bekas gigi yang baru dicabut asalkan tidak ada infeksi, tulang mencukupi, syarat implan terpenuhi, dan pertimbangan indikasi dan kontraindikasi memadai. Tapi, ada risiko dari tindakan ini.Pertama, tulan...

Bone graft & implant gigi pada rahang menciut

Tanya:Tulang rahang saya sudah menciut. Apa masih bisa dipasangi implan?Jawab:Ada teknologi bone graft (cangkok tulang). Dengan teknologi masa kini, pasien yang mengalami penciutan tulang rahang masih punya kemungkinan untuk menerima implan. Hal itu tergantung pada seberapa parah penciutan yang terjadi, kualitas tulang, tebal tulang, dsb.Dokter akan memeriksa foto rontgen panoramik, foto 3D, atau...

Cara memilih dokter gigi implant

Banyak sekali dokter gigi implant menawarkan layanan pemasangan implan. Saking banyaknya, Anda sampai bingung, betulkan mereka semua dokter gigi implan? Siapa di antara mereka yang paling pas bagi Anda? Betulkah mereka benar-benar pakar di bidang implant gigi? Berikut ini tips mudah untuk memilah dan memilih pakar implant gigi.Rekomendasi Dokter Gigi Implan PilihanDokter gigi implant adalah or...

Penyebab infeksi pada implant gigi beserta antisip...

Penyebab infeksi pada implant gigiAda beberapa kemungkinan yang berpotensi jadi penyebab infeksi pada jaringan di sekitar implant gigi. Berikut beberapa di antaranya yang telah diketahui kedokteran gigi modern:Mahkota (crown) terlalu besar.Mahkota yang terlalu besar akan mempertinggi risiko bergesekan dengan jaringan lunak di sekitarnya kala sedang digunakan untuk mengunyah. Lama-kelamaan, jaring...

Jumlah implant gigi maksimal

Tanya:Apa bisa pasang implan gigi lebih dari 5?Jawab:Jumlah implan gigi maksimal yang bisa dipasang pada mulut setiap pasien itu berbeda-berbeda-beda bergantung pada kasusnya karena kondisi setiap pasien itu unik. Tidak ada pasien yang sama persis.Jika memang betul-betul diperlukan, jumlah implan gigi maksimal yang bisa dipasang adalah 28 buah. Tapi, kenyataannya, belum pernah terjadi ada orang...

Gigi implant & makanan keras

Tanya:Apakah gigi implant kuat untuk makanan keras?Jawab:Gigi implant kuat untuk menggigit dan mengunyah makanan keras, seperti jagung, pop corn, kacang, dan daging. Tapi jangan menggunakannya untuk menggigit benda yang sangat keras, seperti membuka tutup botol, membuka kemasan makanan, menggigit atau mengunyah daging yang terlalu keras. Makanan lain yang sangat keras dan terlalu keras juga bisa...

Indikasi Implan Gigi

Indikasi implan gigi umumIndikasi umum untuk perawatan implan gigi meliputi hal-hal berikut ini:Punya motivasi cukup.Pasien perlu punya cukup motivasi agar perawatan implant bisa sukses.Bersikap kooperatif.Kerjasama antara pasien dan dokter adalah salah satu kunci sukses perawatan ini.Restorasi estetika gigi.Restorasi fungsi gigi yang sudah copotFungsi yang direstorasi termasuk fungsi mengunyah ...

Meninggal dunia karena implant gigi????

Implan gigi titanium tidak dilaporkan menyebabkan pasien meninggal jagat dalam jurnal-jurnal ilmiah dengan kredibilitas tinggi. Silakan cari penelitian-penelitian internasional tentang implan gigi modern sejak diterapkan pertama tahun 1965 hingga sekarang (2016). Setengah abad telah berlalu. Mata para peneliti terus-menerus menatap pada bahaya, risiko, dan efek samping metode perawatan modern in...

Operasi pasang implant gigi

Salah satu bagian terpenting dari perawatan ompong dengan implan gigi adalah operasi pasang implant gigi. Tahap PembiusanTahap purwa operasi adalah memberi pasien obat bius. Pada tahap ini, dokter akan memberi obat bius lokal di sekitar lokasi penanaman fikstur gigi ini. Bila bius lokal tidak mempan, dokter akan menggunakan bius total, tapi jarang terjadi. Umumnya pasien sudah cukup dengan b...

Implan gigi sehari jadi

Tanya:Apakah ada macem implan gigi yang langsung pasang sehari jadi? Saya tidak punya waktu menunggu sampai berbulan-bulan karena kesibukan kerja.Jawab:Ada macem implan gigi yang sehari selesai, tapi tidak ada implan gigi yang sehari jadi.Implan gigi: jadi vs selesaiApa beda antara "implan selesai" dan "implan jadi"?Perawatan disebut "selesai" kalau pelaksanaan prosedur sudah sampai tahap akhir. ...

Kelemahan implant gigi

Kita sekarang membahas kelemahan implan gigi sebagai penyeimbang bahasan sebelumnya tentang kelebihannya. Kita tahu bahwa alam mengatur agar segala sesuatu punya kelebihan dan kelemahan. Karena itu rasanya tidak fair kalau kita hanya membahas kelebihan tanpa membahas kelemahan implan. Setelah mengetahui kelemahannya, pasien diharapkan dapat realistik dalam membuat harapan dan bijak dalam penggun...

Jenis dan Klasifikasi Implan Gigi

1. Klasifikasi Berdasarkan Desain ImplanEndostealRamus frame.Fikstur ini bentuknya seperti huruf u. Radiologi menunjukkan implan gigi ramus frame Pasien dengan rahang yang telah menciut masih dapat diimplan dengan implant macem ramus frame.Root form.Fikstur dibuat menyerupai akar gigi asli. Implan berbentuk akar gigiBlade form.Fikstur berbentuk lempengan tipis seperti bilah dan dipasang dengan ca...

Kontraindikasi Implan Gigi

Kontraindikasi implan gigi umumnya relatif dan hanya sedikit saja yang mutlak. Berikut ini kontraindikasi yang telah diketahui:Kontraindikasi Umum AbsolutUsia terlalu muda di bawah 16 tahun.Bisfosfonat. Penggunaan bisfosfonat (obat anti-resorpsi) dipertimbangkan sebagai kontraindikasi implan gigi yang mutlak. Sebabnya, obat ini punya kemungkinan untuk mengakibatkan osteonekrosis pada rahang. P...

Implan gigi cocoknya untuk siapa?

Tanya:Implan gigi cocoknya untuk siapa?Jawab: Implan gigi cocok untuk orang dengan gigi ompong sekurang-kurangnya 1 buah.Punya tipe tulang padat (tulang tipe 1 dan 2). Untuk memastikan prakara ini, dokter gigi akan mengambil foto rontgen panoramik wajah Anda. Tipe tulang padat punya peluang sukses lebih tinggi ketimbang tipe tulang rapuh.Sedang tidak menderita penyakit periodontal. Keberad...

8 Bahaya & Efek Samping Implan Gigi & Antisipasiny...

Implan gigi adalah teknologi terbaru dan termodern untuk merawat pasien penderita ompong. Tingkat keberhasilannya pun sangat tinggi, yaitu 97%. Walau begitu, pasien masih punya peluang 3% untuk mengalami kegagalan, bahaya & efek samping operasi.Apa saja potensi itu dan bagaimana mengantisipasinya? Simak paparan berikut iniBahaya & Efek Samping Implan GigiOperasiImplan gigi ditanam melalui oper...

Mulai berapakah harga implant gigi termurah?

TanyaMulai berapakah harga implan gigi termurah?JawabGigi implant terdiri dari 3 butir barang, yaitu akar tiruan yang disebut implan, abutmen, dan mahkota atau crown.  Gigi implant dan bagian-bagiannyaPerhatikan, benda yang disebut implant itu hanya benda yang berbentuk kerucut pada gambar di atas. Benda ini juga disebut dengan nama akar buatan atau akar gigi buatan. Harga akar tiruan itu saja b...

Jenis Implan Gigi Paling Umum

Tanya:Jenis implan mana yang paling umum dipakai di klinik doctor✚dentist?Jawab:Jenis implant gigi mana yang mesti dipakai itu bergantung pada kasus dan keadaan pasien alih-alih berdasarkan selera dokter gigi implan. Jenis implant gigi yang tepat mengikuti kasus dan kondisi pasien. Kebetulan sebagian besar kasus yang ditangani oleh klinik kami memerlukan implant macem seperti berikut: ...

Apa penyebab infeksi pada gigi yang sudah diimplan...

Tanya:Apa penyebab infeksi pada gigi yang sudah diimplan?Jawab:Infeksi terjadi ketika mikroorganisme atau kuman masuk ke dalam jaringan tubuh manusia, dalam prakara ini adalah gusi dan tulang penopang fikstur, sehingga menyebabkan penyakit. Ada beberapa jalan bagi kuman untuk masuk ke jaringan.Penyebab infeksiImplan longgar.Implan longgar menghasilkan celah antara implant dan jaringan gusi di s...

Persiapan pasang implant gigi

Pasien perlu tahu pentingya persiapan sebelum dilakukan operasi pasang implant gigi. Pasien juga perlu tahu bahwa penerima manfaat dari persiapan yang baik adalah dirinya sendiri, bukan orang lain dan bukan dokter. Semakin baik persiapan yang dilakukannya, makin besar pula manfaat yang dapat dikecapnya.Persiapan pasang implant gigiPakaianKenakan pakaian yang longgar dan nyaman. Lengan baju sebaik...

Harga implant gigi depan

Tanya: Gigi depan saya pecah dan akhirnya dicabut. Tadinya gigi saya bagus, tapi sekarang jadi jelek. Kalau dipasang implan, harga implan gigi depan berapa ya? Jawab: Yang Anda maksud itu harga implan gigi saja, harga implan gigi beserta abutment dan mahkota (crown), atau harga implan gigi beserta abutment dan mahkota lengkap dengan pemasangannya? Perlu Anda ketahui, gigi implant terdiri...

Gigi implant goyang

Ada beberapa penyebab gigi implant goyang, antara lain, kegagalan oseointegrasi, yaitu: jaringan tulang yang berada di sekitar implan gigi tidak memegang atau tidak mencengkeram implant gigi. Apabila jadi, maka jaringan tulang di sekitar implan gigi seharusnya memegang atau mencengkeram implan gigi sehingga implant kokoh tertanam dalam rahang tanpa goyang.Penyebab gigi implant goyang1. Lapisan pe...

Beda gigi palsu permanen & implant gigi/ tanam gig...

Tanya:Apa beda gigi palsu permanen dan implant gigi/ tanam gigi?Jawab:Bedanya, sebutan "gigi palsu permanen" digunakan oleh pemasar, penjual, dan perusahaan, sedangkan "implan gigi" digunakan oleh profesional kesarasan gigi seperti dokter dan perawat. Bisa dikatakan, "gigi palsu permanen" itu istilah dagang, sedangkan "implan gigi" itu istilah kedokteran.Ilmu kedokteran dan profesional kesarasa...

Rahasia awet muda dengan implant gigi

"Benarkah implah gigi membuat orang terlihat tampil awet muda?"Pertanyaan tersebut umum diajukan pasien sehubungan dengan klaim ilmu kedokteran gigi implant tentang manfaat implan gigi untuk menjaga wajah agar awet muda. Lebih lanjut, pasien penasaran juga menanyakan bagaimana penjelasan tentang hubungan antara implant dengan tampilan awet muda. Pertanyaan demikian wajar-wajar saja. Siapa ora...

Implan gigi: Before & After

Foto-foto berikut ini diambil dari layanan perawatan lengkap implan gigi yang telah kami lakukan dengan sukses di klinik gigi & implan gigi doctor✚dentist Jakarta.

Berapa biaya pemasangan implant gigi saja?

Tanya:Berapa biaya pemasangan implan gigi saja?Jawab:Biaya pemasangan implan gigi saja berkisar lebih kurang Rp 8 juta. Biaya ini sudah termasuk harga implant saja. Namun, perlu Anda ketahui, kami selalu memberi perawatan implan gigi lengkap dari purwa sampai akhir, bukan hanya pemasangan implant saja.Paket perawatan lengkap mencakup implan, layanan pemasangan implan, mahkota atau crown, abutm...

Apa larangan setelah pasang gigi implant?

Tanya:Apa larangan setelah pasang gigi implan?Jawab: Rokok. Rokok menyebabkan sel-sel penyangga implant mati sehingga implant copot. Proses ini bisa berlangsung cepat dan bisa pula berlangsung lambat namun pasti terjadi. Plak dan karang gigi dari sisa makanan. Plak dan karang gigi menyebabkan implan gigi berbau busuk. Selain itu, plak dan karang gigi dapat mengakibatkan infeksi yang men...

Berapa lama waktu menunggu implant gigi jadi?

Tanya:Berapa lama waktu menunggu implan gigi jadi?Jawab:Lama waktu menunggu implan gigi jadi bergantung pada kondisi tubuh masing-masing pasien. Karena kondisi tubuh pasien yang satu berbeda dengan kondisi tubuh pasien yang lain, maka lama waktu menunggu juga berbeda-beda.  Dari waktu pemasangan implant gigi sampai implan gigi jadi, yaitu tulang memegang implant gigi, perlu waktu 3-4 bulan pada u...

Bagaimana jika tubuh menolak implant gigi?

Tanya:Apakah tubuh dapat menolak implant gigi? Bagaimana jika tubuh menolak implant gigi? Apa yang harus dilakukan?Jawab:Bahan implan gigi dibuat dari titanium atau zirkonia. Kedua bahan ini telah dikenal diterima oleh tubuh manusia. Kasus penolakan oleh tubuh jarang terjadi. Bila terjadi, maka dokter terpaksa mencopot lagi implan gigi yang telah terpasang itu untuk mencegah dampak yang lebih buru...

Apa yang akan terjadi setelah pemasangan implant g...

Tanya:Apa yang akan terjadi setelah pemasangan implan gigi selesai?Jawab:Setelah pemasangan implan gigi selesai, maka sudah tidak ada lagi luka terbuka. Semua luka operasi telah dijahit bila operasi berlangsung lancar tanpa pendarahan. Pendarahan ini berisiko terjadi pada pasien yang menderita penyakit seperti diabetes atau hemorage tapi tak diberitahukan pada dokter atau bila sudah diberitahukan ...

Kenapa gigi implant saya bau?

Tanya:Kenapa gigi implant saya bau?Jawab:Karena ada sisa-sisa makanan yang terselip dan membusuk. Tempat sisa makanan terselip itu tidak terjangkau oleh sikat gigi sehingga masih tersisa kala Anda menggosok gigi. Setelah menyikat gigi hingga bersih, lengkapi dengan membersihkan celah-celah gigi menggunakan dental floss atau benang gigi. Kelebihan dari benang gigi adalah dapat membersihkan sisa m...

Apakah gigi ompong 3 bisa diimplant?

Tanya:Apakah gigi ompong 3 bisa diimplan?Jawab:Gigi ompong berapapun bisa. Satu bisa, dua bisa, tiga bisa. Bahkan gigi ompong semua juga bisa diimplan. Yang terpenting, indikasi jelas dan Anda memenuhi syarat perawatan implant gigi, khususnya syarat tentang kondisi tulang pendukung gigi. Bila tiga gigi ompong berderet, maka, tergantung indikasi, bisa dipasang 2 implant dengan 3 mahkota (crown)...

Apakah implant gigi aman?

Tanya:Apakah implan gigi aman?Jawab:Asalkan implant ditanam untuk indikasi yang tepat, Anda memenuhi syarat perawatan implan, kontraindikasi sesuai, dan dilakukan oleh dokter gigi implant dengan pengalaman memasang lebih dari 50 implan dan memenuhi syarat untuk pemasangan implant seperti di klinik gigi & implant doctor✚dentist Jakarta, maka implan gigi aman. "Aman" dalam konteks operasi bukan m...

Apakah usia 50 tahun bisa implant gigi?

Tanya:Apakah usia di atas 50 tahun bisa melakukan pemasangan implant gigi? Apa resikonya?Jawab:Implan gigi pada umur Anda tidak berbahaya asalkan Anda memenuhi syarat perawatan implant gigi, khususnya syarat tulang penyangga gigi. Selain itu, perawatan implant juga menurun risikonya bila dilakukan oleh dokter gigi yang telah berpengalaman dan telah memenuhi syarat untuk pemasangan implan gigi s...

Apakah implant gigi total berbahaya?

Tanya:Apakah implan gigi total berbahaya? Mohon penjelasannya.Jawab:Implan gigi seluruh mulut tidak berbahaya selama Anda memenuhi syarat perawatan implant gigi dan perawatan implant dilakukan oleh dokter gigi yang juga telah memenuhi syarat untuk pemasangan implan gigi seperti di klinik gigi & implan gigi doctor✚dentist Jakarta. Hanya saja perlu Anda ketahui bahwa terkadang tidak perlu memasan...

Tempat pasang implant gigi di Jakarta

Tanya: Di mana tempat pasang implan gigi yang relatif murah dan bagus di Jakarta? Jawab: Di klinik doctor✚dentist Jakarta. Klinik gigi & implan gigi ini menyediakan perawatan lengkap implan gigi yang relatif murah dan bagus. Pembayaran bisa dicicil menggunakan kartu kredit. Harga perawatan lengkap sudah termasuk implan gigi, abutmen, dan mahkota (crown) beserta pemasangan dan peraw...

Apa itu implant gigi?

Tanya: Apa itu implant gigi? Jawab: Implan gigi adalah akar gigi tiruan yang ditanamkan ke dalam tulang rahang untuk mengganti gigi sejati yang telah tanggal dan memulihkan fungsi pengunyahan, fungsi bicara, dan fungsi estetika pada diri pasien. Akar gigi tersebut digunakan untuk menopang 1 atau lebih mahkota gigi tiruan, tergantung dari berapa banyak gigi tanggal berderet yang ingin And...

Apakah implant gigi bersifat permanen?

Tanya: Apakah implan gigi bersifat permanen? Jawab: Yang diketahui ilmu pengetahuan kala ini, daya tahan implan gigi terlama adalah sekitar 40 tahun. Tapi, ada pula pasien yang baru beberapa bulan atau beberapa tahun sudah lepas implant giginya karena, misalnya, melanggar pantangan implant gigi. Daya tahan implan gigi tidak dapat dipastikan karena bergantung pada banyak faktor, seperti makanan...

Apa pemasangan implant gigi sakit?

Tanya: Apa pemasangan implan gigi sakit? Jawab: Tidak. Pemasangan implan gigi tidak sakit karena pasien dalam keadaan dibius kala implan gigi dipasang. Sebelum pemasangan implan gigi, dokter gigi akan membius pasien dulu dengan bius lokal atau bius umum, tergantung kasusnya. Pembiusan tersebut menyebabkan pasien jadi mati rasa sementara pada kala pembedahan berlangsung. Pengaruh biu...

Kredit perawatan implant gigi

Tanya: Dokter, apakah bisa saya membayar pemasangan implan gigi dengan cara kredit? Jawab: Ya, pembayaran perawatan implan gigi bisa secara kredit memakai kartu kredit. Bukan hanya perawatan implan gigi, tapi hampir semua perawatan kesarasan di klinik doctor✚dentist bisa dibayar dengan cara kredit menggunakan kartu kredit. Kartu kredit dari umumnya bank diterima asalkan berlogo visa atau m...

Kriteria/ syarat menerima implant gigi

Sekalipun permintaan terhadap perawatan implan gigi cukup tinggi, namun perlu disadari bahwa tidak semua pasien memenuhi syarat untuk menerima perawatan implant gigi. Syarat penerima implan gigi meliputi antara lain: Tulang pendukung implant memadai, yaitu tipe 1 dan tipe 2. Tulang tipe 1 dan 2 mempunyai peluang yang lebih tinggi bagi kesuksesan implant ketimbang tulang tipe 3 dan 4. Ti...

Perlu berapa implant untuk 3 gigi ompong?

Tanya: Dear drg. Andreas, Saya memiliki 3 gigi depan (atas) yang tanggal/ompong lebih dari 7 tahun. Berapa implan gigi yang saya perlukan untuk 3 gigi ompong tersebut? Dan berapa biayanya? Atas perhatiannya, terima kasih. Jawab: Jika bagian yang ompong itu berderet, maka bisa dipasang dua implant dengan 3 mahkota (crown). Tapi jika gigi yang ompong itu tidak berderet, maka Anda perlu 3 implant ...

Persiapan perawatan implant gigi

Tanya: Saya berminat untuk implant gigi. Apa yang harus saya siapkan dan lakukan? Jawab: Tahap persiapan perawatan implan gigi meliputi foto rontgen panoramic dan pemeriksaan kondisi fisik di daerah yang akan diimplan. Anda dapat melakukan foto rontgen panoramic di laboratorium yang paling dekat dengan rumah Anda. Anda juga bisa melakukannya di laboratorium Pramita atau senden yang menyediakan...

Apakah implant gigi akibatkan kebutaan?

Tanya: Apakah implan gigi akibatkan kebutaan? Jawab: Sampai kala ini jurnal-jurnal ilmiah belum ada yang melaporkan bahwa implan gigi dapat menyebabkan kebutaan. L0kasi implan gigi cukup jauh dari mata. Di antara mata dan rahang atas masih terdapat rongga sinus. Andai pun implan gigi di rahang atas gagal, maka paling banter masuk ke rongga sinus dan tidak mencapai rongga bola mata. Sampai tahun ...

Siapa bisa memasang implant gigi?

Tanya: Siapa bisa memasang implant gigi? Jawab: Untuk bisa memasang implan gigi, dokter gigi diwajibkan untuk menempuh pendidikan lanjutan (continuing education). Peserta pendidikan lanjutan di bidang implan gigi adalah dokter gigi. Peserta bisa dokter gigi umum dan tidak harus dokter gigi spesialis bedah mulut. Sampai hari ini, pendidikan ini tertutup bagi kalangan di luar profesi dokter gigi. ...

Tujuan utama implant gigi

Tujuan utama implan gigi adalah untuk merestorasi proses penggantian gigi yang tanggal semirip mungkin dengan gigi asli. Ada 3 bidang yang berkaitan dengan tujuan utama ini, yaitu: Pengunyahan/ mastikasi Keindahan/ estetika Pengucapan A. Pengunyahan/ mastikasi Di bidang pengunyahan, tujuan utama implan gigi adalah merehabilitasi proses pengunyahan semirip mungkin dengan gigi sejati sehin...

Risiko bahaya perawatan implant gigi

Setiap hari manusia berhadapan dengan risiko bahaya. Penyeberang jalan berisiko tertabrak kendaraan. Pejalan kaki berisiko tersandung. Naik sepeda motor berisiko jatuh. Naik pesawat terbang berisiko jatuh. Naik mobil berisiko tabrakan. Tinggal di rumah saja berisiko terkena reruntuhan rumah karena gempa. Perawatan implan gigi juga menghadapkan manusia pada risiko bahaya sebab perawatan ini meliba...

Dokter gigi spesialis implant, adakah?

Kedokteran implan gigi belum menjadi bidang spesialis dalam kedokteran gigi di Indonesia. Seperti yang telah kita ketahui bersama, kedokteran gigi baru memiliki 8 bidang spesialis yang meliputi: Spesialis kedokteran gigi anak (Sp. KGA) Spesialis bedah mulut (Sp. BM) Spesialis konservasi gigi (Sp. KG) Spesialis ortodontik (Sp. Ort) Spesialis prostodontik (Sp. Pros) Spesialis penyakit ...

Apa implant gigi bisa untuk lansia?

Tanya: Apa implan gigi bisa untuk lansia? Jawab: Ya, implan gigi bisa sukses dipasang pada pasien lansia asalkan kondisi tulang rahang masih memadai. Kenyataannya, lansia tertua yang pernah diberi perawatan lengkap implant gigi oleh klinik gigi & implan gigi doctor✚dentist Jakarta adalah seorang nenek yang berumur 80 tahun. Pemasangan ini berlangsung beberapa tahun yang lalu dan terbukti su...

Alergi pada bahan implant gigi

Perusahaan produsen implan gigi pada umumnya menggunakan bahan titanium dan zirkonium untuk membuat implant gigi. Kedua bahan ini aman bagi pasien yang tidak menderita alergi pada titanium atau zirkonium. Ion-ion dari implant yang masuk ke dalam tubuh manusia dapat memicu alergi pada titanium, zirkonium, atau logam. Karena itu, pasien sangat dianjurkan untuk menceritakan kepada dokter gigi menge...

Pengaruh rokok pada implant gigi

Penelitian ilmiah tentang pengaruh rokok terhadap implan gigi menunjukkan bahwa rokok berpengaruh buruk terhadap implant gigi. Tingkat kegagalan implan gigi pada perokok dan bukan perokok masing-masing sebesar 5,6% dan 3,5%. Penelitian tersebut dilakukan pada 7.680 implan gigi dalam rentang waktu 1999-2008. Dari total jumlah itu, 7.359 (95,8%) berhasil dan 321 (4,2%) gagal. Pernahkah Anda ber...

Impan gigi tahan berapa lama?

Sampai kala ini, rekor ketahanan implant gigi terlama dipegang oleh Gösta Larsson dan Sven Johansson. Gösta Larsson adalah pasien implan gigi modern yang pertama sedangkan Sven Johansson adalah yang kedua. Larsson menerima pemasangan implan gigi modern pada tahun 1965 oleh Prof. Per-Ingvar Brånemark. Implan tersebut masih berfungsi hingga dia meninggal jagat pada tahun 2006. Jadi, implant La...

Berapa lama pemasangan implant gigi?

Sampai kala ini, banyak pasien dalam negeri mengira pemasangan implan gigi perlu waktu lama. Penyebabnya, mereka mencampuradukkan antara pemasangan dan perawatan. Sebenarnya, pemasangan implan gigi berlangsung sebentar saja, lebih kurang 1 jam, tergantung kasusnya. Bila kasusnya mudah sekali, maka pemasangan dapat berlangsung 15-30 menit. Bila kasusnya sulit sekali, maka bisa makan waktu lebih da...

Pasang implant gigi tidak sakit

"Apakah pasang implan gigi itu sakit?" Ini pertanyaan yang umum diajukan orang yang ingin pasang implant gigi. Orang kadang keliru membayangkan proses pemasangan implan gigi itu menyakitkan. Penyebabnya, calon penerima implan melihat foto-foto implan gigi di internet sebelum memutuskan untuk menerima perawatan implan. Foto-foto ini biasanya menunjukkan logam titanium menancap pada gusi dan tu...

Implan gigi vs gigi palsu

1. Sistem Implan gigi Sistem implant gigi** Gigi palsu Gigi palsu 2. Metode bedah Implan gigi Akar gigi buatan yang independen ditanamkan ke dalam tulang rahang bawah Gigi palsu Cetakan periodontal disiapkan dan selanjutnya dibuat jadi bentuk gigi standar dan satu set gigi. 3. Akibat pada gigi di dekat bagian ompong Implan gigi Gigi lain tidak diusik. Gigi palsu - ...

Implan gigi vs sistem bridge

1. Sistem Implan gigi Sistem implant gigi** Bridge Sistem bridge** 2. Metode bedah Implan gigi Akar gigi buatan yang independen ditanamkan ke dalam tulang rahang bawah Bridge Gigi yang berada di sebelah kanan dan kiri bagian ompong diperkecil dengan mengikirnya. Bila gigi ompong hanya 1 buah, maka 3 gigi palsu dijadikan satu. Kemudian, gigi palsu di ujung kanan dan kiri dimasukkan ke d...

7 alasan memilih implant gigi

Sekurang-kurangnya ada 7 alasan untuk memilih implan gigi apabila kondisi tubuh Anda memenuhi syarat pemasangan implan. 1. Daya kunyah mendekati gigi asli** Daya kunyah gigi palsu besarnya 10% gigi asli, sedangkan daya kunyah gigi implant besarnya 70-90% gigi asli atau mendekati gigi asli. Implan yang sukses memungkinkan makan makanan keras tapi bukan makanan yang sangat keras dan terlalu...

Pantangan implant gigi

Pantangan implan gigi memengaruhi seberapa awet implant gigi Anda tetap tertanam di tempatnya. Apabila Anda melanggar pantangan ini, maka besar kemungkinan implan gigi akan: Gagal total apabila sedang dalam tahap pemasangan Berumur pendek dan implant terlepas apabila sudah terpasang Kegagalan implan gigi yang dikarnakan pelanggaran pantangan termasuk kegagalan yang dikarnakan oleh fakto...

Harga implant gigi relatif murah

Pada bagian sebelumnya, kita telah membahas kisaran harga paket perawatan implan gigi lengkap. Paket perawatan bukan hanya berisi implan gigi saja, namun juga mencakup abutmen, mahkota (crown), jasa pemasangan, dan jasa perawatan hingga selesai tuntas yang biasanya berlangsung antara 3-9 bulan, tergantung pada kondisi masing-masing pasien. Murah kan? Murah itu relatif. Dibandingkan uang yang diba...

Biaya & harga pasang + rawat implant gigi bagus & ...

Biaya & harga termurah untuk paket pasang+rawat lengkap implan gigi di Jakarta berkisar antara Rp 5 juta hingga Rp 9 juta. Kok bisa? Bukankah paket lengkap biasanya tidak murah? Bisa saja murah karena itu harga cicilan bila Anda membayar dengan cara kredit. Harga angsuran tersebut di atas bukan hanya harga implant saja, namun sudah mencakup abutment, mahkota (crown), pasang ketiganya, dan b...

Kelebihan implant gigi

Kelebihan implan gigi bila dibandingkan gigi palsu konvensional sangat banyak, lebih dari  20. Banyaknya keunggulan menjadikan implan gigi sebagai solusi nyaman untuk mengganti gigi pasien yang hilang. Lebih lagi, implan gigi bisa bertahan lebih dari 10 tahun atau malah seumur hidup bila dirawat dengan baik dan benar. Kelebihan implan gigi dibandingkan gigi palsu konvesional** Punya akar ...

Diabetes mellitus dan implant gigi

Implan gigi aman untuk rehabilitasi gigi pasien diabetes mellitus yang terkontrol dengan baik. Penelitian Naujokat, Kunzendorf, dan Wiltfang (2016: 9) di Jerman dan penelitian Dubey, Gupta, dan Singh (2013: 142) di India menunjukkan, implan gigi pada pasien diabetes ini tampak sama sukses dengan implan pada pasien normal. Di samping itu, tingkat sintasan implant pada pasien diabetes tidak ber...

Prediktor kegagalan implant gigi

Prediktor kegagalan implan gigi yang terutama meliputi faktor-faktor berikut ini: 1) Kualitas tulang yang buruk 2) Periodontik kronis 3) Penyakit sistemik 4) Merokok 5) Karies gigi 6) Infeksi 7) Usia lanjut 8) Lokasi pemasangan implant gigi 9) Implan gigi yang pendek 10) Pembebanan yang tidak di tengah 11) Jumlah implant yang tidak mencukupi 12) Kebiasaan yang fungsinya menyimpang 13)...

Mekanisme osseointegrasi dalam implant gigi

Implan gigi sistem Branemark berbentuk ulir sekrup dan dibuat dari titanium murni komersil (cp ti). Sistem ini dikembangkan sebagai hasil dari riset dasar dalam bidang biologi tulang yang dilakukan oleh Branemark selama dasawarsa 1950an hingga 1960an di Universitas Lund dan Gothenburg. Desain implant ini tidak mengalami modifikasi selama lebih dari seperempat abad penggunaan klinis.Mekanisme Ta...

Brånemark: bapak implant gigi modern

Per Ingvar Brånem, profesor di Institut Bioteknologi Terapan, Universitas Goteborg, Swedia, memasang titanium pada tulang kaki kelinci dan anjing pada tahun 1964. Dia mengamati logam ini berpadu dengan dan tidak dapat lepas dari tulang yang melekat padanya (Brånemark et al., 1964). Peristiwa ini jadi tonggak sejarah implan gigi modern dengan tingkat kesuksesan yang signifikan lebih tinggi ...

Keunggulan titanium untuk implant gigi

Implan gigi komersial pada umumnya menggunakan bahan CP Ti (Commercially Pure Titanium) atau titanium murni menurut standar komersial. Keunggulan titanium telah dibuktikan oleh banyak orang di berbagai penjuru dunia. Lebih dari 1000 ton titanium per tahun dalam berbagai bentuk telah diimplankan pada tubuh manusia. Keunggulan yang ada pada titanium menyebabkan logam ini meningkatkan peluang k...

Prediktor kesuksesan implant gigi

Kesuksesan implan gigi ditentukan oleh banyak faktor yang saling berhubungan satu sama lain. Menurut Parithimarkalaignan and Padmanabhan (2013), faktor yang dapat digunakan untuk meramalkan kesuksesan implan gigi meliputi: Biokompabilitas bahan implant gigi Sifat makroskopik dan mikroskopik permukaan dan rancangan implan gigi Status implant bed dalam konteks kesarasan dan morfologi (ku...

Bahan Implan Gigi

Bahan implan gigi sebelum era 1970an bermacam-macam, misal, kerang dan emas. Akibatnya, tingkat keberhasil implan gigi pada masa itu relatif rendah. Semejak dasawarsa 1970an, implan gigi berbahan Titanium. Dari 2005, implan berbahan Zirkonia mulai diperkenalkan ke pasar. Di antara kedua bahan itu, klinik doctor✚dentist punya pengalaman memasang implan titanium dengan mahkota zirkonia. Alasan...

Implan gigi: solusi nyaman untuk gigi tanggal

Pada purwa abad 21 Masehi ini, implan gigi jadi solusi yang nyaman untuk mengganti gigi tanggal dibandingkan abad-abad sebelumnya. Sebab, metode perawatan ini memberi peluang sukses hingga 97% apabila seluruh syarat terpenuhi.** Bukan hanya itu. Implan juga berfungsi untuk mempertahankan tulang penyangga gigi agar tidak menciut atau menyusut. Saat gigi copot, tulang pendukung gigi tersebut tida...

Antisipasi Risiko Implan Gigi

Antisipasi risiko implan gigi telah lama menjadi subyek penelitian pakar gigi implan. Penelitian tentang faktor-faktor keberhasilan dan kegagalan implan gigi menghasilkan sejumlah rekomendasi untuk mengantisipasi risiko implant gigi. Risiko implant gigi tidak perlu membuat kita cemas karena risiko tersebut relatif jarang terjadi. Selain itu, dokter gigi implant juga telah menyiapkan langkah-lan...

Implan gigi

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Sejarah implant gigi

Sejarah implan gigi jaman purbakala 2500 SM : Bangsa Mesir Purba menstabilkan gigi dengan kawat ligatur dari emas. 500 SM : Bangsa Etruria menggunakan kawat emas untuk mengembalikan fungsi oral manusia. Mereka juga menggunakan gigi tiruan dari tulang lembu sebagai gigi tiruan. Bangsa Fonesia, penduduk sejati Libanon, menggunakan kawat emas untuk menstabilkan gigi. 300 M: Bangsa Fonesia membua...

Pasang implant gigi bagus & murah

Implan gigi itu apa? Implan gigi adalah akar gigi buatan yang ditanam ke dalam tulang rahang untuk mengganti akar gigi asli yang sudah hilang saat gigi copot atau dicabut. Istilah lainnya adalah tanam gigi karena gigi palsu ditanamkan ke dalam tulang rahang pasien. Implan gigi tertanam pada tulang rahang. Pada perawatan implan gigi yang sukses, tulang-tulang di sekitar implant memegang...

Implant gigi harga murah Rp 3 - 5 juta apa betulan...

Saya mendapat pariwara implant gigi dengan harga murah hanya Rp 3 juta. Iklan yang satunya lagi menawarkan implant gigi harga Rp 5 juta. Terus ada yang menawari Rp 7 juta. Kenapa harga di klinik doctor+dentist bisa pada kisaran 12 belas juta? Apa tidak bisa lebih murah lagi? - Penanya - Coba cek pariwara apa pariwara itu cuma menawarkan pasak implant saja (belum termasuk abutment, crown, operasi,...

Kenali infeksi dekat implant gigi sedini mungkin

Infeksi pada jaringan di sekitar implant gigi bisa membuat implant gigi copot. Implan bisa dicegah agar tidak copot. Caranya, kenali infeksi sedini mungkin agar dapat ditangani sedini mungkin.  Infeksi yang berhubungan dengan implant bisa terjadi pada 3 poin waktu, yaitu: 0- 2 minggu setelah operasi implant gigiInfeksi pada titik waktu ini bisa terjadi karena operasi kurang steril. Sehingga...